locus-tag	class	description
H7X63_RS00010	COG0592	DNA-directed DNA polymerase activity
H7X63_RS00020	COG0187	DNA topoisomerase II activity
H7X63_RS00030	COG0586	Pfam SNARE associated Golgi protein
H7X63_RS00035	COG0488	(ABC) transporter
H7X63_RS00060	COG0596	Alpha beta hydrolase
H7X63_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H7X63_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7X63_RS00110	COG0733	neurotransmitter:sodium symporter activity
H7X63_RS00145	COG0583	DNA-binding transcription factor activity
H7X63_RS00150	COG2233	PERMEase
H7X63_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7X63_RS00200	COG2814	Major facilitator Superfamily
H7X63_RS00205	COG0656	L-ascorbic acid biosynthetic process
H7X63_RS00210	COG0583	DNA-binding transcription factor activity
H7X63_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7X63_RS00230	COG1064	alcohol dehydrogenase
H7X63_RS00235	COG2818	Glycosylase
H7X63_RS00250	COG1194	a g-specific adenine glycosylase
H7X63_RS00270	COG2983	Belongs to the UPF0260 family
H7X63_RS00275	COG2133	pyrroloquinoline quinone binding
H7X63_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7X63_RS00285	COG2116	formate transmembrane transporter activity
H7X63_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7X63_RS00310	COG1335	isochorismatase
H7X63_RS00315	COG0385	Bile acid
H7X63_RS00320	COG0534	Mate efflux family protein
H7X63_RS00325	COG1683	Conserved Protein
H7X63_RS00345	COG0625	glutathione transferase activity
H7X63_RS00355	COG1113	amino acid transport
H7X63_RS00365	COG0523	cobalamin synthesis protein
H7X63_RS00375	COG2188	Transcriptional regulator
H7X63_RS00405	COG0010	Belongs to the arginase family
H7X63_RS00415	COG0546	phosphoglycolate phosphatase activity
H7X63_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7X63_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7X63_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7X63_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7X63_RS00525	COG0534	Mate efflux family protein
H7X63_RS00530	COG0436	Aminotransferase
H7X63_RS00535	COG2733	membrane
H7X63_RS00550	COG2918	glutathione biosynthetic process
H7X63_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS00585	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H7X63_RS00595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7X63_RS00605	COG2233	PERMEase
H7X63_RS00610	COG2351	hydroxyisourate hydrolase activity
H7X63_RS00645	COG3706	GGDEF domain
H7X63_RS00660	COG1393	Belongs to the ArsC family
H7X63_RS00665	COG0708	Exodeoxyribonuclease III
H7X63_RS00685	COG0189	ligase activity
H7X63_RS00705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7X63_RS00715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7X63_RS00730	COG4942	peptidase
H7X63_RS00740	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7X63_RS00750	COG2119	membrane
H7X63_RS00755	COG4774	siderophore transport
H7X63_RS00760	COG0426	domain, Protein
H7X63_RS00760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7X63_RS00785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7X63_RS00805	COG1902	pentaerythritol trinitrate reductase activity
H7X63_RS00810	COG1519	Transferase
H7X63_RS00815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7X63_RS00820	COG0668	transmembrane transport
H7X63_RS00830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7X63_RS00835	COG1335	isochorismatase
H7X63_RS00840	COG1522	sequence-specific DNA binding
H7X63_RS00865	COG2198	Histidine kinase
H7X63_RS00865	COG0784	Response regulator, receiver
H7X63_RS00865	COG2205	protein histidine kinase activity
H7X63_RS00870	COG3162	membrane
H7X63_RS00875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7X63_RS00885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7X63_RS00905	COG1309	transcriptional regulator
H7X63_RS00925	COG0352	thiamine-phosphate diphosphorylase activity
H7X63_RS00925	COG0351	phosphomethylpyrimidine kinase
H7X63_RS00925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7X63_RS00935	COG2814	Major facilitator Superfamily
H7X63_RS00950	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7X63_RS00960	COG1113	amino acid transport
H7X63_RS00970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7X63_RS00975	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS00985	COG1335	isochorismatase
H7X63_RS01015	COG2814	Major facilitator Superfamily
H7X63_RS01020	COG0583	DNA-binding transcription factor activity
H7X63_RS01040	COG0667	Aldo Keto reductase
H7X63_RS01070	COG1733	regulation of RNA biosynthetic process
H7X63_RS01075	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7X63_RS01140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7X63_RS01155	COG2329	Antibiotic biosynthesis monooxygenase
H7X63_RS01185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7X63_RS01215	COG0427	acetyl-CoA hydrolase
H7X63_RS01240	COG0659	secondary active sulfate transmembrane transporter activity
H7X63_RS01245	COG4221	oxidoreductase activity
H7X63_RS01250	COG2873	o-acetylhomoserine
H7X63_RS01255	COG0488	(ABC) transporter
H7X63_RS01340	COG0833	amino acid
H7X63_RS01385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7X63_RS01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7X63_RS01405	COG2226	methyltransferase
H7X63_RS01455	COG0067	glutamate synthase
H7X63_RS01455	COG0070	glutamate synthase
H7X63_RS01455	COG0069	glutamate synthase activity
H7X63_RS01460	COG0493	'glutamate synthase
H7X63_RS01470	COG1704	LemA family
H7X63_RS01475	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7X63_RS01495	COG3307	-O-antigen
H7X63_RS01515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7X63_RS01530	COG0194	GDP metabolic process
H7X63_RS01580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7X63_RS01600	COG5380	lipid catabolic process
H7X63_RS01605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7X63_RS01630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7X63_RS01635	COG0277	FAD linked oxidase domain protein
H7X63_RS01645	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7X63_RS01650	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7X63_RS01665	COG1289	transmembrane transporter activity
H7X63_RS01675	COG0628	permease
H7X63_RS01680	COG1192	Involved in chromosome partitioning
H7X63_RS01710	COG0833	amino acid
H7X63_RS01715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7X63_RS01720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7X63_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS01770	COG0583	DNA-binding transcription factor activity
H7X63_RS01815	COG0517	IMP dehydrogenase activity
H7X63_RS01820	COG1983	PspC domain protein
H7X63_RS01830	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS01845	COG0408	coproporphyrinogen oxidase activity
H7X63_RS01865	COG0513	Belongs to the DEAD box helicase family
H7X63_RS01875	COG1127	ABC transporter
H7X63_RS01880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7X63_RS01890	COG2854	intermembrane phospholipid transfer
H7X63_RS01900	COG0598	Magnesium transport protein CorA
H7X63_RS01910	COG0494	nUDIX hydrolase
H7X63_RS01915	COG1040	competence protein
H7X63_RS01920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7X63_RS01940	COG1946	Acyl-CoA thioesterase
H7X63_RS01945	COG1301	dicarboxylic acid transport
H7X63_RS01960	COG1959	2 iron, 2 sulfur cluster binding
H7X63_RS01965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7X63_RS01965	COG1017	nitric oxide dioxygenase activity
H7X63_RS01970	COG0433	COG0433 Predicted ATPase
H7X63_RS01975	COG0626	cystathionine gamma-synthase activity
H7X63_RS02130	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS02135	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7X63_RS02165	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H7X63_RS02170	COG0339	signal peptide processing
H7X63_RS02175	COG0557	exoribonuclease II activity
H7X63_RS02220	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7X63_RS02225	COG2169	Transcriptional regulator
H7X63_RS02230	COG0697	spore germination
H7X63_RS02235	COG1295	ribonuclease BN
H7X63_RS02270	COG1702	phosphate starvation-inducible protein PhoH
H7X63_RS02280	COG1196	nuclear chromosome segregation
H7X63_RS02280	COG0741	lytic transglycosylase activity
H7X63_RS02280	COG0739	heme binding
H7X63_RS02310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7X63_RS02315	COG1183	phosphatidylcholine synthase activity
H7X63_RS02360	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS02365	COG1309	transcriptional regulator
H7X63_RS02380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7X63_RS02385	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS02405	COG2969	positive regulation of protein catabolic process
H7X63_RS02415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7X63_RS02430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7X63_RS02435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7X63_RS02455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7X63_RS02465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7X63_RS02470	COG1408	metallophosphoesterase
H7X63_RS02480	COG2199	diguanylate cyclase activity
H7X63_RS02540	COG1607	acyl-coa hydrolase
H7X63_RS02570	COG2350	Protein conserved in bacteria
H7X63_RS02580	COG0613	PHP domain protein
H7X63_RS02585	COG3781	membrane
H7X63_RS02595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7X63_RS02600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7X63_RS02610	COG1862	Preprotein translocase
H7X63_RS02640	COG2205	protein histidine kinase activity
H7X63_RS02645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H7X63_RS02665	COG0726	polysaccharide deacetylase
H7X63_RS02670	COG0463	Glycosyl transferase, family 2
H7X63_RS02675	COG0438	transferase activity, transferring glycosyl groups
H7X63_RS02740	COG0625	glutathione transferase activity
H7X63_RS02745	COG0583	DNA-binding transcription factor activity
H7X63_RS02750	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS02755	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS02765	COG2205	protein histidine kinase activity
H7X63_RS02770	COG0745	RESPONSE REGULATOR receiver
H7X63_RS02775	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H7X63_RS02795	COG2096	Adenosyltransferase
H7X63_RS02845	COG0285	dihydrofolate synthase activity
H7X63_RS02865	COG0450	alkyl hydroperoxide reductase
H7X63_RS02880	COG0477	Major facilitator Superfamily
H7X63_RS02885	COG1272	protein, Hemolysin III
H7X63_RS02915	COG0183	Belongs to the thiolase family
H7X63_RS02920	COG2207	Transcriptional regulator
H7X63_RS02940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7X63_RS02960	COG0183	Belongs to the thiolase family
H7X63_RS02970	COG2885	chlorophyll binding
H7X63_RS02970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H7X63_RS02980	COG1690	Belongs to the RtcB family
H7X63_RS02985	COG0833	amino acid
H7X63_RS02995	COG2233	PERMEase
H7X63_RS03000	COG1217	gtp-binding protein TYPA
H7X63_RS03025	COG2094	Belongs to the DNA glycosylase MPG family
H7X63_RS03030	COG4772	TonB-dependent receptor
H7X63_RS03045	COG1902	pentaerythritol trinitrate reductase activity
H7X63_RS03060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7X63_RS03065	COG0354	folic acid binding
H7X63_RS03075	COG3189	MarR family transcriptional regulator
H7X63_RS03080	COG2824	Alkylphosphonate utilization operon protein PhnA
H7X63_RS03085	COG3422	double-strand break repair
H7X63_RS03125	COG0840	transmembrane signaling receptor activity
H7X63_RS03145	COG5510	response to toxic substance
H7X63_RS03155	COG2832	Protein of unknown function (DUF454)
H7X63_RS03160	COG1376	ErfK ybiS ycfS ynhG family protein
H7X63_RS03200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7X63_RS03210	COG1289	transmembrane transporter activity
H7X63_RS03215	COG2814	Major facilitator Superfamily
H7X63_RS03235	COG1115	amino acid carrier protein
H7X63_RS03240	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7X63_RS03245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7X63_RS03250	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H7X63_RS03290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7X63_RS03300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7X63_RS03305	COG1077	Cell shape determining protein MreB Mrl
H7X63_RS03310	COG1792	Involved in formation and maintenance of cell shape
H7X63_RS03315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7X63_RS03320	COG0424	maF-like protein
H7X63_RS03325	COG1530	ribonuclease E activity
H7X63_RS03335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7X63_RS03345	COG0560	Phosphoserine phosphatase
H7X63_RS03355	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7X63_RS03380	COG2207	Transcriptional regulator
H7X63_RS03400	COG1113	amino acid transport
H7X63_RS03405	COG2828	Protein conserved in bacteria
H7X63_RS03410	COG0142	geranyltranstransferase activity
H7X63_RS03415	COG2315	Protein conserved in bacteria
H7X63_RS03430	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7X63_RS03450	COG2194	sulfuric ester hydrolase activity
H7X63_RS03455	COG0745	RESPONSE REGULATOR receiver
H7X63_RS03460	COG0642	Histidine kinase
H7X63_RS03470	COG0004	ammonium transporteR
H7X63_RS03475	COG0583	DNA-binding transcription factor activity
H7X63_RS03495	COG0525	valine-tRNA ligase activity
H7X63_RS03505	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS03515	COG0393	Putative heavy-metal-binding
H7X63_RS03520	COG0393	Putative heavy-metal-binding
H7X63_RS03525	COG1538	Outer membrane efflux protein
H7X63_RS03535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7X63_RS03540	COG0671	phosphoesterase, PA-phosphatase related
H7X63_RS03570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7X63_RS03585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7X63_RS03585	COG1648	precorrin-2 dehydrogenase activity
H7X63_RS03590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7X63_RS03595	COG1733	regulation of RNA biosynthetic process
H7X63_RS03605	COG0531	amino acid
H7X63_RS03620	COG0321	lipoyl(octanoyl) transferase activity
H7X63_RS03625	COG2921	Belongs to the UPF0250 family
H7X63_RS03665	COG2009	succinate dehydrogenase
H7X63_RS03670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H7X63_RS03675	COG1053	succinate dehydrogenase
H7X63_RS03680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7X63_RS03705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7X63_RS03725	COG2354	Protein conserved in bacteria
H7X63_RS03730	COG2321	neutral zinc metallopeptidase
H7X63_RS03805	COG0589	response to stress
H7X63_RS03825	COG0505	Belongs to the CarA family
H7X63_RS03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7X63_RS03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7X63_RS03905	COG0477	Major facilitator Superfamily
H7X63_RS03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7X63_RS03925	COG1597	lipid kinase activity
H7X63_RS03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7X63_RS03960	COG0584	glycerophosphoryl diester phosphodiesterase
H7X63_RS03980	COG0741	lytic transglycosylase activity
H7X63_RS04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7X63_RS04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7X63_RS04040	COG0778	Nitroreductase
H7X63_RS04055	COG1929	Belongs to the glycerate kinase type-1 family
H7X63_RS04060	COG0243	molybdopterin cofactor binding
H7X63_RS04065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7X63_RS04070	COG3339	Conserved Protein
H7X63_RS04080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H7X63_RS04095	COG1113	amino acid transport
H7X63_RS04105	COG0019	diaminopimelate decarboxylase activity
H7X63_RS04115	COG1280	lysine exporter protein (LysE YggA)
H7X63_RS04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7X63_RS04150	COG0463	Glycosyl transferase, family 2
H7X63_RS04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7X63_RS04205	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7X63_RS04210	COG1136	(ABC) transporter
H7X63_RS04215	COG2333	competence protein COMEC
H7X63_RS04215	COG0658	competence protein
H7X63_RS04225	COG0616	signal peptide processing
H7X63_RS04225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H7X63_RS04230	COG0596	Alpha beta hydrolase
H7X63_RS04235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7X63_RS04245	COG0628	permease
H7X63_RS04280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7X63_RS04300	COG0823	Involved in the tonB-independent uptake of proteins
H7X63_RS04320	COG0824	Thioesterase
H7X63_RS04325	COG1473	amidohydrolase
H7X63_RS04345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7X63_RS04345	COG0047	phosphoribosylformylglycinamidine synthase activity
H7X63_RS04350	COG2814	Major facilitator Superfamily
H7X63_RS04360	COG1024	Enoyl-CoA hydratase
H7X63_RS04365	COG1051	belongs to the nudix hydrolase family
H7X63_RS04365	COG1056	cytidyltransferase-related domain
H7X63_RS04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7X63_RS04390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7X63_RS04405	COG4625	pathogenesis
H7X63_RS04410	COG0583	DNA-binding transcription factor activity
H7X63_RS04415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7X63_RS04420	COG4208	sulfate ABC transporter
H7X63_RS04425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H7X63_RS04435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7X63_RS04440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7X63_RS04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7X63_RS04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7X63_RS04480	COG0681	Belongs to the peptidase S26 family
H7X63_RS04495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7X63_RS04505	COG1381	Involved in DNA repair and RecF pathway recombination
H7X63_RS04510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7X63_RS04520	COG4221	oxidoreductase activity
H7X63_RS04550	COG0436	Aminotransferase
H7X63_RS04570	COG0556	nucleotide-excision repair
H7X63_RS04625	COG2070	2-Nitropropane dioxygenase
H7X63_RS04655	COG1215	transferase activity, transferring glycosyl groups
H7X63_RS04670	COG0415	Belongs to the DNA photolyase family
H7X63_RS04680	COG1252	NADH dehydrogenase
H7X63_RS04685	COG1686	Belongs to the peptidase S11 family
H7X63_RS04700	COG1187	pseudouridine synthase activity
H7X63_RS04725	COG0477	Major facilitator Superfamily
H7X63_RS04730	COG0583	DNA-binding transcription factor activity
H7X63_RS04735	COG1823	symporter activity
H7X63_RS04745	COG0612	Peptidase, M16
H7X63_RS04770	COG0352	thiamine-phosphate diphosphorylase activity
H7X63_RS04805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7X63_RS04820	COG1309	transcriptional regulator
H7X63_RS04830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7X63_RS04835	COG0076	glutamate decarboxylase activity
H7X63_RS04845	COG1522	sequence-specific DNA binding
H7X63_RS04850	COG3961	Belongs to the TPP enzyme family
H7X63_RS04855	COG1113	amino acid transport
H7X63_RS04860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7X63_RS04865	COG0573	inorganic phosphate transmembrane transporter activity
H7X63_RS04875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7X63_RS04880	COG0616	signal peptide processing
H7X63_RS04890	COG3328	transposase activity
H7X63_RS04920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7X63_RS04925	COG1686	Belongs to the peptidase S11 family
H7X63_RS04950	COG0583	DNA-binding transcription factor activity
H7X63_RS04955	COG1067	ATP-dependent peptidase activity
H7X63_RS05000	COG1966	Carbon starvation protein
H7X63_RS05005	COG2879	small protein
H7X63_RS05035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7X63_RS05035	COG2508	Transcriptional regulator
H7X63_RS05055	COG1113	amino acid transport
H7X63_RS05060	COG0583	DNA-binding transcription factor activity
H7X63_RS05065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7X63_RS05070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7X63_RS05080	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS05085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7X63_RS05090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7X63_RS05090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H7X63_RS05125	COG2814	Major facilitator Superfamily
H7X63_RS05130	COG4948	Mandelate Racemase Muconate Lactonizing
H7X63_RS05140	COG1309	transcriptional regulator
H7X63_RS05160	COG1741	Belongs to the pirin family
H7X63_RS05170	COG2964	Protein conserved in bacteria
H7X63_RS05185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7X63_RS05190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7X63_RS05195	COG4605	iron ion homeostasis
H7X63_RS05200	COG4604	ABC transporter, ATP-binding protein
H7X63_RS05205	COG4607	ABC-type enterochelin transport system periplasmic component
H7X63_RS05210	COG4774	siderophore transport
H7X63_RS05220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7X63_RS05225	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7X63_RS05230	COG1535	isochorismatase
H7X63_RS05230	COG3433	isochorismatase activity
H7X63_RS05245	COG1132	(ABC) transporter
H7X63_RS05250	COG1132	(ABC) transporter
H7X63_RS05255	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7X63_RS05265	COG1169	isochorismate synthase
H7X63_RS05280	COG3739	integral membrane protein
H7X63_RS05305	COG0302	gtp cyclohydrolase
H7X63_RS05315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7X63_RS05345	COG0308	aminopeptidase N
H7X63_RS05350	COG0512	Glutamine amidotransferase of anthranilate synthase
H7X63_RS05545	COG5410	chromosome segregation
H7X63_RS05715	COG0582	viral genome integration into host DNA
H7X63_RS05730	COG0174	glutamine synthetase
H7X63_RS05740	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7X63_RS05775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7X63_RS05780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7X63_RS05785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7X63_RS05805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7X63_RS05810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7X63_RS05815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7X63_RS05830	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS05835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7X63_RS05840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7X63_RS05850	COG2223	nitrite transmembrane transporter activity
H7X63_RS05860	COG0024	Methionine aminopeptidase
H7X63_RS05865	COG0052	Belongs to the universal ribosomal protein uS2 family
H7X63_RS05880	COG2207	Transcriptional regulator
H7X63_RS05905	COG2951	lytic endotransglycosylase activity
H7X63_RS05910	COG0772	Belongs to the SEDS family
H7X63_RS05925	COG0842	Transport permease protein
H7X63_RS05930	COG1131	(ABC) transporter
H7X63_RS05975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7X63_RS05990	COG4215	(ABC) transporter
H7X63_RS05995	COG4160	amino acid transport
H7X63_RS06000	COG4598	ABC transporter
H7X63_RS06010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7X63_RS06015	COG0826	peptidase U32
H7X63_RS06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7X63_RS06035	COG1720	tRNA m6t6A37 methyltransferase activity
H7X63_RS06045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7X63_RS06060	COG0642	Histidine kinase
H7X63_RS06070	COG0494	nUDIX hydrolase
H7X63_RS06080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7X63_RS06085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7X63_RS06090	COG3139	Protein of unknown function (DUF1315)
H7X63_RS06095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7X63_RS06100	COG1301	dicarboxylic acid transport
H7X63_RS06105	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS06110	COG2819	hydrolase of the alpha beta superfamily
H7X63_RS06120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7X63_RS06130	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7X63_RS06135	COG1234	tRNA 3'-trailer cleavage
H7X63_RS06165	COG2363	Small membrane protein
H7X63_RS06185	COG0513	Belongs to the DEAD box helicase family
H7X63_RS06195	COG0778	Nitroreductase
H7X63_RS06225	COG1286	toxin biosynthetic process
H7X63_RS06250	COG4783	chaperone-mediated protein folding
H7X63_RS06255	COG1610	YqeY-like protein
H7X63_RS06355	COG3111	PFAM Bacterial OB fold (BOF) protein
H7X63_RS06380	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7X63_RS06385	COG0786	glutamate:sodium symporter activity
H7X63_RS06395	COG2186	Transcriptional regulator
H7X63_RS06445	COG0477	Major facilitator Superfamily
H7X63_RS06470	COG2985	domain, Protein
H7X63_RS06480	COG2995	paraquat-inducible protein a
H7X63_RS06485	COG3008	intermembrane lipid transfer
H7X63_RS06485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7X63_RS06505	COG0482	sulfurtransferase activity
H7X63_RS06520	COG0488	(ABC) transporter
H7X63_RS06525	COG3173	Aminoglycoside phosphotransferase
H7X63_RS06535	COG2433	Pfam Transposase IS66
H7X63_RS06575	COG1301	dicarboxylic acid transport
H7X63_RS06585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7X63_RS06590	COG2011	ABC-type metal ion transport system permease component
H7X63_RS06595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7X63_RS06600	COG1464	Belongs to the NlpA lipoprotein family
H7X63_RS06605	COG0151	Belongs to the GarS family
H7X63_RS06610	COG0138	bifunctional purine biosynthesis protein purh
H7X63_RS06615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H7X63_RS06645	COG2308	Evidence 4 Homologs of previously reported genes of
H7X63_RS06655	COG1305	Transglutaminase-like
H7X63_RS06665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7X63_RS06670	COG0305	Participates in initiation and elongation during chromosome replication
H7X63_RS06695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7X63_RS06705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7X63_RS06710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7X63_RS06735	COG1649	PFAM Uncharacterised BCR, COG1649
H7X63_RS06735	COG0726	polysaccharide deacetylase
H7X63_RS06740	COG1215	transferase activity, transferring glycosyl groups
H7X63_RS06745	COG3658	cytochrome
H7X63_RS06755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7X63_RS06770	COG0583	DNA-binding transcription factor activity
H7X63_RS06790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7X63_RS06795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7X63_RS06810	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS06815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7X63_RS06820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7X63_RS06845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H7X63_RS06850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H7X63_RS06860	COG2205	protein histidine kinase activity
H7X63_RS06865	COG0745	RESPONSE REGULATOR receiver
H7X63_RS06870	COG0174	glutamine synthetase
H7X63_RS06890	COG0729	surface antigen
H7X63_RS06915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7X63_RS06920	COG2814	Major facilitator Superfamily
H7X63_RS06935	COG0583	DNA-binding transcription factor activity
H7X63_RS06950	COG1187	pseudouridine synthase activity
H7X63_RS06970	COG0802	atpase or kinase
H7X63_RS06975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7X63_RS06985	COG1923	regulation of RNA biosynthetic process
H7X63_RS06990	COG0697	spore germination
H7X63_RS07005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7X63_RS07015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7X63_RS07020	COG0519	Catalyzes the synthesis of GMP from XMP
H7X63_RS07020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7X63_RS07025	COG4302	ethanolamine ammonia-lyase activity
H7X63_RS07030	COG4303	Ethanolamine ammonia lyase large subunit
H7X63_RS07035	COG0531	amino acid
H7X63_RS07055	COG1454	alcohol dehydrogenase
H7X63_RS07060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7X63_RS07070	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H7X63_RS07090	COG0308	aminopeptidase N
H7X63_RS07120	COG1605	Chorismate mutase
H7X63_RS07135	COG1309	transcriptional regulator
H7X63_RS07145	COG0668	transmembrane transport
H7X63_RS07180	COG4773	Receptor
H7X63_RS07200	COG0488	(ABC) transporter
H7X63_RS07205	COG0589	response to stress
H7X63_RS07230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7X63_RS07240	COG3135	benzoate transporter
H7X63_RS07245	COG1522	sequence-specific DNA binding
H7X63_RS07255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7X63_RS07260	COG0583	DNA-binding transcription factor activity
H7X63_RS07270	COG0183	Belongs to the thiolase family
H7X63_RS07280	COG2030	dehydratase
H7X63_RS07285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7X63_RS07300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7X63_RS07310	COG0824	Thioesterase
H7X63_RS07315	COG1454	alcohol dehydrogenase
H7X63_RS07325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7X63_RS07345	COG0069	glutamate synthase activity
H7X63_RS07375	COG2814	Major facilitator Superfamily
H7X63_RS07390	COG0511	ligase activity, forming carbon-carbon bonds
H7X63_RS07410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7X63_RS07410	COG1116	anion transmembrane transporter activity
H7X63_RS07415	COG0745	RESPONSE REGULATOR receiver
H7X63_RS07425	COG2146	nitrite reductase [NAD(P)H] activity
H7X63_RS07425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7X63_RS07430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7X63_RS07435	COG0243	molybdopterin cofactor binding
H7X63_RS07445	COG0243	molybdopterin cofactor binding
H7X63_RS07450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7X63_RS07465	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7X63_RS07465	COG0315	cyclic pyranopterin monophosphate synthase activity
H7X63_RS07470	COG0303	'Molybdopterin
H7X63_RS07480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7X63_RS07485	COG0697	spore germination
H7X63_RS07505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H7X63_RS07510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7X63_RS07565	COG2204	response regulator
H7X63_RS07570	COG3852	Histidine kinase
H7X63_RS07590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7X63_RS07595	COG0575	Belongs to the CDS family
H7X63_RS07630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7X63_RS07645	COG2137	regulation of response to DNA damage stimulus
H7X63_RS07655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7X63_RS07660	COG1011	Hydrolase
H7X63_RS07685	COG1522	sequence-specific DNA binding
H7X63_RS07695	COG1113	amino acid transport
H7X63_RS07710	COG0659	secondary active sulfate transmembrane transporter activity
H7X63_RS07715	COG2135	peptidase activity
H7X63_RS07730	COG3300	MHYT domain
H7X63_RS07730	COG5001	Diguanylate cyclase
H7X63_RS07750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7X63_RS07750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7X63_RS07750	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H7X63_RS07755	COG1105	Belongs to the carbohydrate kinase PfkB family
H7X63_RS07760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7X63_RS07760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7X63_RS07790	COG0024	Methionine aminopeptidase
H7X63_RS07795	COG0583	DNA-binding transcription factor activity
H7X63_RS07805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7X63_RS07810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7X63_RS07815	COG0517	IMP dehydrogenase activity
H7X63_RS07815	COG0516	GMP reductase activity
H7X63_RS07840	COG0552	protein localization to endoplasmic reticulum
H7X63_RS07850	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H7X63_RS07865	COG4890	Cyd operon protein YbgT
H7X63_RS07870	COG1294	oxidase, subunit
H7X63_RS07885	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7X63_RS07895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7X63_RS07900	COG4774	siderophore transport
H7X63_RS07915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7X63_RS07920	COG0569	domain protein
H7X63_RS07925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7X63_RS07955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H7X63_RS07960	COG0542	response to heat
H7X63_RS07985	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7X63_RS07985	COG1902	pentaerythritol trinitrate reductase activity
H7X63_RS08030	COG2323	membrane
H7X63_RS08035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7X63_RS08045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7X63_RS08050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7X63_RS08055	COG0183	Belongs to the thiolase family
H7X63_RS08060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7X63_RS08065	COG0596	Alpha beta hydrolase
H7X63_RS08070	COG2271	Major facilitator Superfamily
H7X63_RS08075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7X63_RS08080	COG3485	protocatechuate 3,4-dioxygenase
H7X63_RS08085	COG3485	protocatechuate 3,4-dioxygenase
H7X63_RS08090	COG0710	3-dehydroquinate dehydratase activity
H7X63_RS08095	COG3420	alginic acid biosynthetic process
H7X63_RS08100	COG3659	wide pore channel activity
H7X63_RS08105	COG4993	Dehydrogenase
H7X63_RS08115	COG2391	methyltransferase activity
H7X63_RS08130	COG1414	Transcriptional regulator
H7X63_RS08135	COG0583	DNA-binding transcription factor activity
H7X63_RS08140	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS08165	COG2814	Major facilitator Superfamily
H7X63_RS08175	COG0154	amidase activity
H7X63_RS08195	COG4638	Rieske (2fe-2S)
H7X63_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS08215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7X63_RS08225	COG3733	amine oxidase
H7X63_RS08235	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS08255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7X63_RS08260	COG0183	Belongs to the thiolase family
H7X63_RS08265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7X63_RS08270	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7X63_RS08280	COG4829	muconolactone delta-isomerase
H7X63_RS08285	COG4948	Mandelate Racemase Muconate Lactonizing
H7X63_RS08290	COG0583	DNA-binding transcription factor activity
H7X63_RS08300	COG2186	Transcriptional regulator
H7X63_RS08320	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS08340	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS08350	COG3829	transcription factor binding
H7X63_RS08360	COG3162	membrane
H7X63_RS08375	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS08390	COG0753	catalase activity
H7X63_RS08410	COG1846	Transcriptional regulator
H7X63_RS08415	COG1902	pentaerythritol trinitrate reductase activity
H7X63_RS08415	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7X63_RS08425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7X63_RS08455	COG1309	transcriptional regulator
H7X63_RS08465	COG1335	isochorismatase
H7X63_RS08470	COG0583	DNA-binding transcription factor activity
H7X63_RS08480	COG0475	glutathione-regulated potassium exporter activity
H7X63_RS08480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7X63_RS08490	COG1473	amidohydrolase
H7X63_RS08500	COG2831	hemolysin activation secretion protein
H7X63_RS08505	COG3210	domain, Protein
H7X63_RS08535	COG2188	Transcriptional regulator
H7X63_RS08550	COG0583	DNA-binding transcription factor activity
H7X63_RS08580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7X63_RS08600	COG1566	PFAM secretion protein HlyD family protein
H7X63_RS08615	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS08620	COG0129	dihydroxy-acid dehydratase activity
H7X63_RS08630	COG0583	DNA-binding transcription factor activity
H7X63_RS08635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7X63_RS08645	COG2084	Dehydrogenase
H7X63_RS08650	COG2207	Transcriptional regulator
H7X63_RS08665	COG1064	alcohol dehydrogenase
H7X63_RS08675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7X63_RS08680	COG1120	ATPase activity
H7X63_RS08700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7X63_RS08815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H7X63_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS08880	COG2207	Transcriptional regulator
H7X63_RS08890	COG2205	protein histidine kinase activity
H7X63_RS08895	COG0745	RESPONSE REGULATOR receiver
H7X63_RS08900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7X63_RS08905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7X63_RS08910	COG1538	Outer membrane efflux protein
H7X63_RS08920	COG2072	flavoprotein involved in K transport
H7X63_RS08940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7X63_RS08960	COG3539	Fimbrial protein
H7X63_RS08990	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H7X63_RS09000	COG0753	catalase activity
H7X63_RS09015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7X63_RS09080	COG3433	isochorismatase activity
H7X63_RS09080	COG1535	isochorismatase
H7X63_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS09090	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H7X63_RS09095	COG4149	molybdate abc transporter
H7X63_RS09100	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7X63_RS09110	COG4638	Rieske (2fe-2S)
H7X63_RS09115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7X63_RS09120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7X63_RS09120	COG0543	2 iron, 2 sulfur cluster binding
H7X63_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS09160	COG2207	Transcriptional regulator
H7X63_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS09175	COG2610	gluconate transmembrane transporter activity
H7X63_RS09185	COG0583	DNA-binding transcription factor activity
H7X63_RS09195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7X63_RS09200	COG2031	fatty acid transporter
H7X63_RS09205	COG0183	Belongs to the thiolase family
H7X63_RS09210	COG0583	DNA-binding transcription factor activity
H7X63_RS09215	COG0583	DNA-binding transcription factor activity
H7X63_RS09230	COG1027	Aspartate ammonia-lyase
H7X63_RS09240	COG0477	Major facilitator Superfamily
H7X63_RS09260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7X63_RS09265	COG4521	taurine ABC transporter
H7X63_RS09280	COG2188	Transcriptional regulator
H7X63_RS09290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7X63_RS09295	COG1733	regulation of RNA biosynthetic process
H7X63_RS09300	COG2207	Transcriptional regulator
H7X63_RS09300	COG3708	Transcriptional regulator
H7X63_RS09315	COG0730	response to heat
H7X63_RS09325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7X63_RS09325	COG3453	Protein conserved in bacteria
H7X63_RS09335	COG3781	membrane
H7X63_RS09340	COG1063	alcohol dehydrogenase
H7X63_RS09350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7X63_RS09355	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7X63_RS09360	COG0022	dehydrogenase e1 component
H7X63_RS09365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7X63_RS09370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7X63_RS09385	COG3706	GGDEF domain
H7X63_RS09400	COG0133	tryptophan synthase activity
H7X63_RS09410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7X63_RS09445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7X63_RS09470	COG2226	methyltransferase
H7X63_RS09530	COG0842	Transport permease protein
H7X63_RS09535	COG0842	Transport permease protein
H7X63_RS09540	COG1131	(ABC) transporter
H7X63_RS09555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7X63_RS09560	COG4773	Receptor
H7X63_RS09580	COG0730	response to heat
H7X63_RS09585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7X63_RS09605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H7X63_RS09620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7X63_RS09660	COG4264	IucA IucC family
H7X63_RS09665	COG4264	IucA IucC family
H7X63_RS09685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7X63_RS09700	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS09705	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS09710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7X63_RS09715	COG2207	Transcriptional regulator
H7X63_RS09720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7X63_RS09725	COG0776	regulation of translation
H7X63_RS09750	COG0822	iron-sulfur transferase activity
H7X63_RS09755	COG0316	Belongs to the HesB IscA family
H7X63_RS09785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7X63_RS09805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7X63_RS09810	COG0702	epimerase
H7X63_RS09845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7X63_RS09855	COG0339	signal peptide processing
H7X63_RS09905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7X63_RS09910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7X63_RS09940	COG0776	regulation of translation
H7X63_RS10005	COG0084	hydrolase, TatD family'
H7X63_RS10025	COG1663	tetraacyldisaccharide 4'-kinase activity
H7X63_RS10030	COG1132	(ABC) transporter
H7X63_RS10040	COG0811	peptide transport
H7X63_RS10045	COG1475	DNA binding
H7X63_RS10050	COG1192	Involved in chromosome partitioning
H7X63_RS10060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7X63_RS10075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7X63_RS10080	COG0191	fructose-bisphosphate aldolase activity
H7X63_RS10100	COG0424	maF-like protein
H7X63_RS10105	COG2850	peptidyl-arginine hydroxylation
H7X63_RS10115	COG0640	Transcriptional regulator
H7X63_RS10125	COG3619	membrane
H7X63_RS10130	COG3122	Protein conserved in bacteria
H7X63_RS10135	COG1132	(ABC) transporter
H7X63_RS10155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7X63_RS10160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7X63_RS10170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7X63_RS10170	COG0506	proline dehydrogenase activity
H7X63_RS10170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7X63_RS10175	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7X63_RS10190	COG3698	Phosphodiester glycosidase
H7X63_RS10200	COG2353	YceI-like domain
H7X63_RS10210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7X63_RS10255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7X63_RS10255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7X63_RS10280	COG3539	Fimbrial protein
H7X63_RS10285	COG3121	Chaperone
H7X63_RS10310	COG0697	spore germination
H7X63_RS10320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7X63_RS10330	COG0583	DNA-binding transcription factor activity
H7X63_RS10350	COG1309	transcriptional regulator
H7X63_RS10365	COG1522	sequence-specific DNA binding
H7X63_RS10375	COG1126	abc transporter atp-binding protein
H7X63_RS10380	COG0765	amino acid transport
H7X63_RS10385	COG0765	amino acid transport
H7X63_RS10415	COG1464	Belongs to the NlpA lipoprotein family
H7X63_RS10425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7X63_RS10430	COG2011	ABC-type metal ion transport system permease component
H7X63_RS10435	COG0012	GTP binding
H7X63_RS10460	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7X63_RS10500	COG0386	Belongs to the glutathione peroxidase family
H7X63_RS10510	COG0436	Aminotransferase
H7X63_RS10550	COG3634	alkyl hydroperoxide reductase activity
H7X63_RS10565	COG0583	DNA-binding transcription factor activity
H7X63_RS10570	COG0798	PFAM Bile acid sodium symporter
H7X63_RS10575	COG0640	Transcriptional regulator
H7X63_RS10590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7X63_RS10600	COG0583	DNA-binding transcription factor activity
H7X63_RS10610	COG1953	Uracil, thiamine, allantoin
H7X63_RS10620	COG2175	clavaminate synthase activity
H7X63_RS10625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7X63_RS10630	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7X63_RS10635	COG4521	taurine ABC transporter
H7X63_RS10645	COG0477	Major facilitator Superfamily
H7X63_RS10665	COG1271	oxidase subunit
H7X63_RS10670	COG1294	oxidase, subunit
H7X63_RS10680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7X63_RS10700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7X63_RS10720	COG3052	prosthetic group binding
H7X63_RS10725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H7X63_RS10735	COG2814	Major facilitator Superfamily
H7X63_RS10765	COG1346	cytolysis
H7X63_RS10775	COG0583	DNA-binding transcription factor activity
H7X63_RS10780	COG0625	glutathione transferase activity
H7X63_RS10785	COG0625	glutathione transferase activity
H7X63_RS10790	COG0583	DNA-binding transcription factor activity
H7X63_RS10805	COG1045	serine acetyltransferase
H7X63_RS10810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7X63_RS10815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7X63_RS10825	COG1280	lysine exporter protein (LysE YggA)
H7X63_RS10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7X63_RS10845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7X63_RS10850	COG1126	abc transporter atp-binding protein
H7X63_RS10855	COG0765	amino acid transport
H7X63_RS10860	COG0765	amino acid transport
H7X63_RS10880	COG2205	protein histidine kinase activity
H7X63_RS10880	COG0784	Response regulator, receiver
H7X63_RS10900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7X63_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS10970	COG0583	DNA-binding transcription factor activity
H7X63_RS10990	COG0318	PFAM AMP-dependent synthetase and ligase
H7X63_RS10995	COG1309	transcriptional regulator
H7X63_RS11000	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS11005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7X63_RS11010	COG1024	Enoyl-CoA hydratase
H7X63_RS11015	COG4770	biotin carboxylase activity
H7X63_RS11025	COG0583	DNA-binding transcription factor activity
H7X63_RS11040	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS11050	COG2814	Major facilitator Superfamily
H7X63_RS11060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7X63_RS11065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7X63_RS11070	COG2814	Major facilitator Superfamily
H7X63_RS11075	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS11080	COG1024	Enoyl-CoA hydratase
H7X63_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS11090	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7X63_RS11095	COG0183	Belongs to the thiolase family
H7X63_RS11105	COG2814	Major facilitator Superfamily
H7X63_RS11115	COG1024	Enoyl-CoA hydratase
H7X63_RS11130	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS11135	COG2814	Major facilitator Superfamily
H7X63_RS11140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7X63_RS11145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7X63_RS11160	COG3842	ATPase activity
H7X63_RS11165	COG1840	ABC-type Fe3 transport system, periplasmic component
H7X63_RS11175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7X63_RS11180	COG1414	Transcriptional regulator
H7X63_RS11190	COG0583	DNA-binding transcription factor activity
H7X63_RS11195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7X63_RS11200	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS11210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7X63_RS11220	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS11225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7X63_RS11230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7X63_RS11235	COG2267	carboxylic ester hydrolase activity
H7X63_RS11255	COG3038	cytochrome b561
H7X63_RS11260	COG0753	catalase activity
H7X63_RS11290	COG2050	protein possibly involved in aromatic compounds catabolism
H7X63_RS11300	COG3327	negative regulation of DNA-templated transcription, initiation
H7X63_RS11305	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H7X63_RS11310	COG0183	Belongs to the thiolase family
H7X63_RS11315	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7X63_RS11320	COG1024	Enoyl-CoA hydratase
H7X63_RS11325	COG1024	Enoyl-CoA hydratase
H7X63_RS11330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7X63_RS11335	COG2151	metal-sulfur cluster biosynthetic enzyme
H7X63_RS11340	COG3396	Phenylacetate-CoA oxygenase
H7X63_RS11345	COG3460	Phenylacetate-CoA oxygenase
H7X63_RS11350	COG3396	Phenylacetate-CoA oxygenase
H7X63_RS11355	COG2030	dehydratase
H7X63_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS11360	COG1760	l-serine dehydratase
H7X63_RS11365	COG0531	amino acid
H7X63_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS11385	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7X63_RS11395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7X63_RS11415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7X63_RS11425	COG0789	Transcriptional regulator
H7X63_RS11440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7X63_RS11455	COG2807	transmembrane transport
H7X63_RS11460	COG0590	tRNA wobble adenosine to inosine editing
H7X63_RS11580	COG1116	anion transmembrane transporter activity
H7X63_RS11585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7X63_RS11595	COG0864	Transcriptional regulator
H7X63_RS11615	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7X63_RS11620	COG0439	Biotin carboxylase
H7X63_RS11635	COG1063	alcohol dehydrogenase
H7X63_RS11645	COG1309	transcriptional regulator
H7X63_RS11665	COG0038	chloride channel
H7X63_RS11670	COG4770	biotin carboxylase activity
H7X63_RS11690	COG1914	H( )-stimulated, divalent metal cation uptake system
H7X63_RS11695	COG0583	DNA-binding transcription factor activity
H7X63_RS11745	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7X63_RS11765	COG2814	Major facilitator Superfamily
H7X63_RS11775	COG1560	Kdo2-lipid A biosynthetic process
H7X63_RS11785	COG5006	permease, DMT superfamily
H7X63_RS11790	COG1522	sequence-specific DNA binding
H7X63_RS11805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H7X63_RS11815	COG4122	O-methyltransferase activity
H7X63_RS11845	COG1538	Outer membrane efflux protein
H7X63_RS11850	COG1137	ATPase activity
H7X63_RS11855	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H7X63_RS11865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7X63_RS11870	COG0517	IMP dehydrogenase activity
H7X63_RS11870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7X63_RS11905	COG2814	Major facilitator Superfamily
H7X63_RS11940	COG1278	Cold shock
H7X63_RS11945	COG1280	lysine exporter protein (LysE YggA)
H7X63_RS11975	COG1570	exodeoxyribonuclease VII activity
H7X63_RS12025	COG0583	DNA-binding transcription factor activity
H7X63_RS12030	COG4638	Rieske (2fe-2S)
H7X63_RS12035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7X63_RS12040	COG0633	Ferredoxin
H7X63_RS12040	COG0543	2 iron, 2 sulfur cluster binding
H7X63_RS12045	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS12050	COG3135	benzoate transporter
H7X63_RS12055	COG2814	Major facilitator Superfamily
H7X63_RS12070	COG1643	Atp-dependent helicase
H7X63_RS12075	COG0450	alkyl hydroperoxide reductase
H7X63_RS12085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7X63_RS12095	COG3634	alkyl hydroperoxide reductase activity
H7X63_RS12115	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7X63_RS12120	COG0625	glutathione transferase activity
H7X63_RS12130	COG2885	chlorophyll binding
H7X63_RS12165	COG0542	response to heat
H7X63_RS12180	COG1765	OsmC-like protein
H7X63_RS12195	COG0667	Aldo Keto reductase
H7X63_RS12210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7X63_RS12220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7X63_RS12230	COG0527	aspartate kinase activity
H7X63_RS12240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7X63_RS12250	COG3038	cytochrome b561
H7X63_RS12255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7X63_RS12260	COG2252	PERMEase
H7X63_RS12270	COG2072	flavoprotein involved in K transport
H7X63_RS12285	COG1741	Belongs to the pirin family
H7X63_RS12290	COG1309	transcriptional regulator
H7X63_RS12315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7X63_RS12355	COG1902	pentaerythritol trinitrate reductase activity
H7X63_RS12355	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7X63_RS12365	COG2203	Gaf domain
H7X63_RS12365	COG4251	negative regulation of phosphorylation
H7X63_RS12365	COG5001	Diguanylate cyclase
H7X63_RS12365	COG3706	GGDEF domain
H7X63_RS12375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7X63_RS12395	COG4172	Belongs to the ABC transporter superfamily
H7X63_RS12400	COG4239	(ABC) transporter, permease
H7X63_RS12405	COG4174	ABC transporter (Permease)
H7X63_RS12415	COG1388	LysM domain
H7X63_RS12415	COG0741	lytic transglycosylase activity
H7X63_RS12415	COG1388	LysM domain
H7X63_RS12415	COG0741	lytic transglycosylase activity
H7X63_RS12420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7X63_RS12460	COG0583	DNA-binding transcription factor activity
H7X63_RS12465	COG1279	arginine transmembrane transporter activity
H7X63_RS12485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7X63_RS12490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7X63_RS12495	COG0006	proline dipeptidase activity
H7X63_RS12530	COG2194	sulfuric ester hydrolase activity
H7X63_RS12575	COG0739	heme binding
H7X63_RS12900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7X63_RS12925	COG3384	dioxygenase
H7X63_RS12935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7X63_RS12940	COG2878	Part of a membrane complex involved in electron transport
H7X63_RS12945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7X63_RS12970	COG0768	penicillin binding
H7X63_RS12975	COG0742	ribosomal rna small subunit methyltransferase
H7X63_RS12990	COG0830	nickel cation binding
H7X63_RS13000	COG0804	urea catabolic process
H7X63_RS13040	COG1253	flavin adenine dinucleotide binding
H7X63_RS13045	COG2851	Citrate transporter
H7X63_RS13100	COG1773	rubredoxin
H7X63_RS13105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7X63_RS13115	COG0583	DNA-binding transcription factor activity
H7X63_RS13140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7X63_RS13145	COG4181	ATPase activity
H7X63_RS13190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7X63_RS13210	COG0306	phosphate transporter
H7X63_RS13220	COG3958	Transketolase
H7X63_RS13225	COG3959	Transketolase, thiamine diphosphate binding domain
H7X63_RS13230	COG2271	Major facilitator Superfamily
H7X63_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS13240	COG0583	DNA-binding transcription factor activity
H7X63_RS13255	COG2223	nitrite transmembrane transporter activity
H7X63_RS13260	COG2207	Transcriptional regulator
H7X63_RS13265	COG2066	Belongs to the glutaminase family
H7X63_RS13270	COG0242	peptide deformylase activity
H7X63_RS13275	COG0477	Major facilitator Superfamily
H7X63_RS13285	COG0028	Belongs to the TPP enzyme family
H7X63_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS13305	COG2267	carboxylic ester hydrolase activity
H7X63_RS13315	COG2271	Major facilitator Superfamily
H7X63_RS13320	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7X63_RS13330	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS13350	COG1414	Transcriptional regulator
H7X63_RS13365	COG1024	Enoyl-CoA hydratase
H7X63_RS13375	COG1215	transferase activity, transferring glycosyl groups
H7X63_RS13380	COG1649	PFAM Uncharacterised BCR, COG1649
H7X63_RS13380	COG0726	polysaccharide deacetylase
H7X63_RS13390	COG4681	YaeQ
H7X63_RS13400	COG0523	cobalamin synthesis protein
H7X63_RS13410	COG1607	acyl-coa hydrolase
H7X63_RS13420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7X63_RS13425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7X63_RS13430	COG1309	transcriptional regulator
H7X63_RS13455	COG2040	homocysteine
H7X63_RS13460	COG0531	amino acid
H7X63_RS13515	COG1595	DNA-templated transcription, initiation
H7X63_RS13525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7X63_RS13530	COG0477	Major facilitator Superfamily
H7X63_RS13550	COG0084	hydrolase, TatD family'
H7X63_RS13585	COG0629	single-stranded DNA binding
H7X63_RS13640	COG0582	viral genome integration into host DNA
H7X63_RS13775	COG2026	Addiction module toxin, RelE StbE family
H7X63_RS13970	COG1484	DNA-dependent DNA replication
H7X63_RS14060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7X63_RS14130	COG0405	Gamma-glutamyltransferase
H7X63_RS14135	COG2814	Major facilitator Superfamily
H7X63_RS14145	COG2050	protein possibly involved in aromatic compounds catabolism
H7X63_RS14160	COG1090	epimerase
H7X63_RS14180	COG0420	3'-5' exonuclease activity
H7X63_RS14205	COG0735	belongs to the Fur family
H7X63_RS14210	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7X63_RS14230	COG0121	glutamine amidotransferase
H7X63_RS14245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7X63_RS14255	COG0210	DNA helicase
H7X63_RS14260	COG2885	chlorophyll binding
H7X63_RS14265	COG0204	Acyl-transferase
H7X63_RS14280	COG2894	cell division
H7X63_RS14300	COG1280	lysine exporter protein (LysE YggA)
H7X63_RS14305	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7X63_RS14305	COG1674	ftsk spoiiie
H7X63_RS14310	COG0492	ferredoxin-NADP+ reductase activity
H7X63_RS14315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H7X63_RS14325	COG0456	acetyltransferase
H7X63_RS14370	COG1981	membrane
H7X63_RS14385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7X63_RS14385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7X63_RS14405	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS14415	COG0657	acetylesterase activity
H7X63_RS14425	COG0473	3-isopropylmalate dehydrogenase activity
H7X63_RS14430	COG0583	DNA-binding transcription factor activity
H7X63_RS14450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7X63_RS14475	COG0564	pseudouridine synthase activity
H7X63_RS14485	COG0358	DNA primase activity
H7X63_RS14500	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H7X63_RS14530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7X63_RS14560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7X63_RS14570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7X63_RS14570	COG0352	thiamine-phosphate diphosphorylase activity
H7X63_RS14570	COG0351	phosphomethylpyrimidine kinase
H7X63_RS14575	COG1652	LysM domain
H7X63_RS14600	COG1399	metal-binding, possibly nucleic acid-binding protein
H7X63_RS14605	COG3101	peptidyl-lysine hydroxylation
H7X63_RS14610	COG0009	L-threonylcarbamoyladenylate synthase
H7X63_RS14615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7X63_RS14620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7X63_RS14635	COG4106	trans-aconitate 2-methyltransferase activity
H7X63_RS14650	COG2226	methyltransferase
H7X63_RS14650	COG0596	Alpha beta hydrolase
H7X63_RS14650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7X63_RS14655	COG1877	trehalose-phosphatase activity
H7X63_RS14660	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H7X63_RS14665	COG2223	nitrite transmembrane transporter activity
H7X63_RS14685	COG1196	nuclear chromosome segregation
H7X63_RS14695	COG0730	response to heat
H7X63_RS14710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7X63_RS14720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7X63_RS14770	COG0489	protein tyrosine kinase activity
H7X63_RS14780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7X63_RS14780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7X63_RS14810	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H7X63_RS14815	COG2081	HI0933 family
H7X63_RS14825	COG0668	transmembrane transport
H7X63_RS14845	COG0583	DNA-binding transcription factor activity
H7X63_RS14865	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7X63_RS14870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7X63_RS14900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H7X63_RS14940	COG0745	RESPONSE REGULATOR receiver
H7X63_RS14960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7X63_RS14970	COG2205	protein histidine kinase activity
H7X63_RS15040	COG4993	Dehydrogenase
H7X63_RS15065	COG0384	phenazine biosynthesis protein PhzF
H7X63_RS15085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7X63_RS15100	COG0583	DNA-binding transcription factor activity
H7X63_RS15140	COG0583	DNA-binding transcription factor activity
H7X63_RS15155	COG0583	DNA-binding transcription factor activity
H7X63_RS15160	COG1053	succinate dehydrogenase
H7X63_RS15170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7X63_RS15175	COG2814	Major facilitator Superfamily
H7X63_RS15180	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS15185	COG0583	DNA-binding transcription factor activity
H7X63_RS15190	COG1063	alcohol dehydrogenase
H7X63_RS15220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7X63_RS15225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7X63_RS15230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7X63_RS15245	COG3667	copper resistance
H7X63_RS15250	COG2132	Multicopper oxidase
H7X63_RS15260	COG0561	phosphatase activity
H7X63_RS15265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7X63_RS15290	COG1214	PFAM Peptidase M22, glycoprotease
H7X63_RS15340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7X63_RS15350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7X63_RS15355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7X63_RS15360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7X63_RS15420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7X63_RS15430	COG1846	Transcriptional regulator
H7X63_RS15435	COG1764	response to oxidative stress
H7X63_RS15485	COG0037	tRNA processing
H7X63_RS15495	COG0248	Ppx GppA phosphatase
H7X63_RS15525	COG0072	phenylalanine-tRNA ligase activity
H7X63_RS15565	COG1238	metal cluster binding
H7X63_RS15570	COG0625	glutathione transferase activity
H7X63_RS15585	COG0318	PFAM AMP-dependent synthetase and ligase
H7X63_RS15590	COG3028	Belongs to the UPF0307 family
H7X63_RS15595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7X63_RS15615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7X63_RS15620	COG0617	tRNA 3'-terminal CCA addition
H7X63_RS15625	COG1555	photosystem II stabilization
H7X63_RS15630	COG3956	TIGRFAM MazG family protein
H7X63_RS15640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7X63_RS15660	COG0784	Response regulator, receiver
H7X63_RS15660	COG5002	protein histidine kinase activity
H7X63_RS15660	COG2205	protein histidine kinase activity
H7X63_RS15665	COG1024	Enoyl-CoA hydratase
H7X63_RS15670	COG2084	Dehydrogenase
H7X63_RS15675	COG3622	Belongs to the hyi family
H7X63_RS15705	COG0697	spore germination
H7X63_RS15715	COG2814	Major facilitator Superfamily
H7X63_RS15720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7X63_RS15730	COG0583	DNA-binding transcription factor activity
H7X63_RS15740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7X63_RS15755	COG0084	hydrolase, TatD family'
H7X63_RS15770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H7X63_RS15800	COG0440	acetolactate synthase activity
H7X63_RS15805	COG0028	Belongs to the TPP enzyme family
H7X63_RS15830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7X63_RS15835	COG1136	(ABC) transporter
H7X63_RS15835	COG0577	efflux transmembrane transporter activity
H7X63_RS15840	COG1538	Outer membrane efflux protein
H7X63_RS15855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H7X63_RS15860	COG1162	GTPase activity
H7X63_RS15870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7X63_RS15890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7X63_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS15935	COG2986	histidine ammonia-lyase
H7X63_RS15950	COG0318	PFAM AMP-dependent synthetase and ligase
H7X63_RS15960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7X63_RS16005	COG1426	Protein conserved in bacteria
H7X63_RS16040	COG0793	Belongs to the peptidase S41A family
H7X63_RS16055	COG2267	carboxylic ester hydrolase activity
H7X63_RS16065	COG1012	belongs to the aldehyde dehydrogenase family
H7X63_RS16070	COG3265	gluconokinase activity
H7X63_RS16080	COG0800	Aldolase
H7X63_RS16095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7X63_RS16100	COG0857	belongs to the CobB CobQ family
H7X63_RS16100	COG0280	phosphate acetyltransferase
H7X63_RS16105	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H7X63_RS16105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H7X63_RS16125	COG0740	serine-type endopeptidase activity
H7X63_RS16135	COG4774	siderophore transport
H7X63_RS16145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7X63_RS16155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7X63_RS16155	COG2813	Specifically methylates the guanine in position
H7X63_RS16255	COG0788	formyltetrahydrofolate deformylase activity
H7X63_RS16280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7X63_RS16280	COG4651	solute:proton antiporter activity
H7X63_RS16300	COG0724	RNA recognition motif
H7X63_RS16305	COG0210	DNA helicase
H7X63_RS16330	COG1733	regulation of RNA biosynthetic process
H7X63_RS16340	COG2900	Belongs to the SlyX family
H7X63_RS16345	COG0488	(ABC) transporter
H7X63_RS16350	COG1280	lysine exporter protein (LysE YggA)
H7X63_RS16355	COG1560	Kdo2-lipid A biosynthetic process
H7X63_RS16365	COG1301	dicarboxylic acid transport
H7X63_RS16425	COG0473	3-isopropylmalate dehydrogenase activity
H7X63_RS16490	COG0583	DNA-binding transcription factor activity
H7X63_RS16500	COG0625	glutathione transferase activity
H7X63_RS16505	COG2378	regulation of single-species biofilm formation
H7X63_RS16510	COG0546	phosphoglycolate phosphatase activity
H7X63_RS16520	COG1530	ribonuclease E activity
H7X63_RS16525	COG0318	PFAM AMP-dependent synthetase and ligase
H7X63_RS16540	COG0583	DNA-binding transcription factor activity
H7X63_RS16545	COG4221	oxidoreductase activity
H7X63_RS16550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7X63_RS16610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7X63_RS16650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H7X63_RS16655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7X63_RS16670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7X63_RS16680	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H7X63_RS16680	COG0644	oxidoreductase
H7X63_RS16685	COG0425	Belongs to the sulfur carrier protein TusA family
H7X63_RS16690	COG4535	Mg2 and Co2 transporter CorC
H7X63_RS16700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7X63_RS16720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7X63_RS16725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7X63_RS16725	COG0475	glutathione-regulated potassium exporter activity
H7X63_RS16730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7X63_RS16740	COG0484	heat shock protein binding
H7X63_RS16745	COG0789	Transcriptional regulator
H7X63_RS16750	COG0598	Magnesium transport protein CorA
H7X63_RS16765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7X63_RS16770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7X63_RS16775	COG1074	ATP-dependent DNA helicase activity
H7X63_RS16780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H7X63_RS16800	COG2226	methyltransferase
H7X63_RS16815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7X63_RS16820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7X63_RS16835	COG2111	Na H antiporter
H7X63_RS16835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7X63_RS16840	COG1006	Multisubunit Na H antiporter MnhC subunit
H7X63_RS16845	COG0651	ATP synthesis coupled electron transport
H7X63_RS16850	COG1863	multisubunit Na H antiporter MnhE subunit
H7X63_RS16855	COG2212	antiporter activity
H7X63_RS16860	COG1320	monovalent cation:proton antiporter activity
H7X63_RS16875	COG0195	Participates in both transcription termination and antitermination
H7X63_RS16925	COG0237	dephospho-CoA kinase activity
H7X63_RS16935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7X63_RS16950	COG0497	DNA recombination
H7X63_RS16960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7X63_RS16990	COG2169	Transcriptional regulator
H7X63_RS16990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7X63_RS16995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7X63_RS17060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7X63_RS17075	COG0326	Molecular chaperone. Has ATPase activity
H7X63_RS17090	COG2056	Na+-H+ antiporter family
H7X63_RS17095	COG0596	Alpha beta hydrolase
H7X63_RS17190	COG0546	phosphoglycolate phosphatase activity
H7X63_RS17195	COG1716	ATPase activity
H7X63_RS17240	COG0181	hydroxymethylbilane synthase activity
H7X63_RS17250	COG3275	phosphorelay sensor kinase activity
H7X63_RS17270	COG1538	Outer membrane efflux protein
H7X63_RS17275	COG0697	spore germination
H7X63_RS17300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7X63_RS17305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7X63_RS17310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7X63_RS17315	COG0772	Belongs to the SEDS family
H7X63_RS17340	COG4974	Belongs to the 'phage' integrase family
H7X63_RS17345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7X63_RS17355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7X63_RS17365	COG2197	response regulator
H7X63_RS17380	COG0793	Belongs to the peptidase S41A family
H7X63_RS17385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7X63_RS17390	COG0795	lipopolysaccharide-transporting ATPase activity
H7X63_RS17430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7X63_RS17430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7X63_RS17440	COG0004	ammonium transporteR
H7X63_RS17445	COG0347	Belongs to the P(II) protein family
H7X63_RS17455	COG0606	chelatase, subunit chli
H7X63_RS17540	COG0659	secondary active sulfate transmembrane transporter activity
H7X63_RS17545	COG0589	response to stress
H7X63_RS17575	COG0606	chelatase, subunit chli
H7X63_RS17590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7X63_RS17605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7X63_RS17620	COG0318	PFAM AMP-dependent synthetase and ligase
H7X63_RS17630	COG0477	Major facilitator Superfamily
H7X63_RS17635	COG2860	membrane
H7X63_RS17645	COG1253	flavin adenine dinucleotide binding
H7X63_RS17665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7X63_RS17700	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7X63_RS17710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7X63_RS17745	COG1309	transcriptional regulator
H7X63_RS17780	COG0758	DNA mediated transformation
H7X63_RS17790	COG0697	spore germination
H7X63_RS17795	COG1309	transcriptional regulator
H7X63_RS17810	COG0386	Belongs to the glutathione peroxidase family
H7X63_RS17880	COG1121	(ABC) transporter
H7X63_RS17885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7X63_RS17890	COG1280	lysine exporter protein (LysE YggA)
H7X63_RS17895	COG2837	iron assimilation
H7X63_RS17900	COG0281	malic enzyme
H7X63_RS17950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7X63_RS17950	COG0519	Catalyzes the synthesis of GMP from XMP
H7X63_RS17955	COG4399	Belongs to the UPF0754 family
H7X63_RS17960	COG2259	Doxx family
H7X63_RS17965	COG0586	Pfam SNARE associated Golgi protein
H7X63_RS17980	COG1192	Involved in chromosome partitioning
H7X63_RS17990	COG0271	Belongs to the BolA IbaG family
H7X63_RS18015	COG3916	Acyl-homoserine-lactone synthase
H7X63_RS18020	COG0477	Major facilitator Superfamily
H7X63_RS18025	COG1024	Enoyl-CoA hydratase
H7X63_RS18030	COG1024	Enoyl-CoA hydratase
H7X63_RS18035	COG1960	acyl-CoA dehydrogenase activity
H7X63_RS18040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7X63_RS18060	COG1113	amino acid transport
H7X63_RS18065	COG1113	amino acid transport
H7X63_RS18070	COG0251	oxidation-reduction process
H7X63_RS18110	COG0564	pseudouridine synthase activity
H7X63_RS18160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7X63_RS18175	COG1802	Transcriptional regulator
H7X63_RS18185	COG1448	Aminotransferase
H7X63_RS18190	COG0277	FAD linked oxidase domain protein
H7X63_RS18200	COG2186	Transcriptional regulator
H7X63_RS18210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7X63_RS18215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7X63_RS18230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7X63_RS18235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7X63_RS18240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7X63_RS18285	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS18290	COG1083	cytidylyl-transferase
H7X63_RS18295	COG0673	inositol 2-dehydrogenase activity
H7X63_RS18300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7X63_RS18305	COG1045	serine acetyltransferase
H7X63_RS18310	COG2089	acid synthase
H7X63_RS18315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7X63_RS18320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7X63_RS18330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H7X63_RS18335	COG1596	polysaccharide export
H7X63_RS18360	COG0728	peptidoglycan biosynthetic process
H7X63_RS18365	COG3023	N-Acetylmuramoyl-L-alanine amidase
H7X63_RS18420	COG0546	phosphoglycolate phosphatase activity
H7X63_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
H7X63_RS18445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7X63_RS18450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7X63_RS18455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7X63_RS18460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7X63_RS18465	COG1116	anion transmembrane transporter activity
H7X63_RS18470	COG1309	transcriptional regulator
H7X63_RS18475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7X63_RS18485	COG0196	riboflavin kinase activity
H7X63_RS18490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7X63_RS18500	COG1047	Peptidyl-prolyl cis-trans
H7X63_RS18540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7X63_RS18545	COG0657	acetylesterase activity
H7X63_RS18595	COG2951	lytic endotransglycosylase activity
H7X63_RS18600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7X63_RS18615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7X63_RS18625	COG3328	transposase activity
H7X63_RS18630	COG0671	phosphoesterase, PA-phosphatase related
H7X63_RS18635	COG0861	Integral membrane protein TerC family
H7X63_RS18645	COG0754	glutathionylspermidine amidase activity
H7X63_RS18655	COG0402	S-adenosylhomocysteine deaminase activity
H7X63_RS18670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7X63_RS18675	COG1230	cation diffusion facilitator family transporter
H7X63_RS18690	COG0706	membrane insertase activity