locus-tag	class	description
HUF98_RS00010	COG0592	DNA-directed DNA polymerase activity
HUF98_RS00020	COG0187	DNA topoisomerase II activity
HUF98_RS00030	COG0586	Pfam SNARE associated Golgi protein
HUF98_RS00035	COG0488	(ABC) transporter
HUF98_RS00060	COG0596	Alpha beta hydrolase
HUF98_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUF98_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUF98_RS00100	COG0625	glutathione transferase activity
HUF98_RS00110	COG0733	neurotransmitter:sodium symporter activity
HUF98_RS00145	COG0583	DNA-binding transcription factor activity
HUF98_RS00150	COG2233	PERMEase
HUF98_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS00200	COG2814	Major facilitator Superfamily
HUF98_RS00205	COG0656	L-ascorbic acid biosynthetic process
HUF98_RS00210	COG0583	DNA-binding transcription factor activity
HUF98_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_RS00230	COG1064	alcohol dehydrogenase
HUF98_RS00235	COG2818	Glycosylase
HUF98_RS00250	COG1194	a g-specific adenine glycosylase
HUF98_RS00270	COG2983	Belongs to the UPF0260 family
HUF98_RS00275	COG2133	pyrroloquinoline quinone binding
HUF98_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUF98_RS00285	COG2116	formate transmembrane transporter activity
HUF98_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_RS00310	COG1335	isochorismatase
HUF98_RS00315	COG0385	Bile acid
HUF98_RS00320	COG0534	Mate efflux family protein
HUF98_RS00325	COG1683	Conserved Protein
HUF98_RS00345	COG0625	glutathione transferase activity
HUF98_RS00355	COG1113	amino acid transport
HUF98_RS00365	COG0523	cobalamin synthesis protein
HUF98_RS00375	COG2188	Transcriptional regulator
HUF98_RS00405	COG0010	Belongs to the arginase family
HUF98_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUF98_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUF98_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HUF98_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUF98_RS00485	COG0753	catalase activity
HUF98_RS00535	COG0534	Mate efflux family protein
HUF98_RS00540	COG0436	Aminotransferase
HUF98_RS00545	COG2733	membrane
HUF98_RS00560	COG2918	glutathione biosynthetic process
HUF98_RS00620	COG3150	esterase
HUF98_RS00630	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HUF98_RS00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_RS00655	COG2233	PERMEase
HUF98_RS00660	COG2351	hydroxyisourate hydrolase activity
HUF98_RS00695	COG3706	GGDEF domain
HUF98_RS00710	COG1393	Belongs to the ArsC family
HUF98_RS00715	COG0708	Exodeoxyribonuclease III
HUF98_RS00760	COG0189	ligase activity
HUF98_RS00780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUF98_RS00790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUF98_RS00805	COG4942	peptidase
HUF98_RS00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUF98_RS00825	COG2119	membrane
HUF98_RS00830	COG4774	siderophore transport
HUF98_RS00835	COG0426	domain, Protein
HUF98_RS00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_RS00860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUF98_RS00880	COG1902	pentaerythritol trinitrate reductase activity
HUF98_RS00885	COG1519	Transferase
HUF98_RS00890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUF98_RS00895	COG0668	transmembrane transport
HUF98_RS00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUF98_RS00910	COG1335	isochorismatase
HUF98_RS00915	COG1522	sequence-specific DNA binding
HUF98_RS00940	COG0784	Response regulator, receiver
HUF98_RS00940	COG2198	Histidine kinase
HUF98_RS00940	COG2205	protein histidine kinase activity
HUF98_RS00945	COG3162	membrane
HUF98_RS00950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUF98_RS00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUF98_RS00980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUF98_RS00985	COG1309	transcriptional regulator
HUF98_RS01005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUF98_RS01005	COG0352	thiamine-phosphate diphosphorylase activity
HUF98_RS01005	COG0351	phosphomethylpyrimidine kinase
HUF98_RS01015	COG2814	Major facilitator Superfamily
HUF98_RS01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HUF98_RS01040	COG1113	amino acid transport
HUF98_RS01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUF98_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS01065	COG1335	isochorismatase
HUF98_RS01110	COG2814	Major facilitator Superfamily
HUF98_RS01115	COG0583	DNA-binding transcription factor activity
HUF98_RS01165	COG0667	Aldo Keto reductase
HUF98_RS01195	COG1733	regulation of RNA biosynthetic process
HUF98_RS01200	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_RS01210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUF98_RS01265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUF98_RS01280	COG2329	Antibiotic biosynthesis monooxygenase
HUF98_RS01295	COG1132	(ABC) transporter
HUF98_RS01315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUF98_RS01345	COG0427	acetyl-CoA hydrolase
HUF98_RS01370	COG0659	secondary active sulfate transmembrane transporter activity
HUF98_RS01375	COG4221	oxidoreductase activity
HUF98_RS01385	COG0488	(ABC) transporter
HUF98_RS01450	COG0833	amino acid
HUF98_RS01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUF98_RS01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUF98_RS01515	COG2226	methyltransferase
HUF98_RS01565	COG0067	glutamate synthase
HUF98_RS01565	COG0070	glutamate synthase
HUF98_RS01565	COG0069	glutamate synthase activity
HUF98_RS01570	COG0493	'glutamate synthase
HUF98_RS01580	COG1704	LemA family
HUF98_RS01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUF98_RS01605	COG3307	-O-antigen
HUF98_RS01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUF98_RS01640	COG0194	GDP metabolic process
HUF98_RS01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUF98_RS01710	COG5380	lipid catabolic process
HUF98_RS01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUF98_RS01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUF98_RS01745	COG0277	FAD linked oxidase domain protein
HUF98_RS01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HUF98_RS01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_RS01775	COG1289	transmembrane transporter activity
HUF98_RS01785	COG0628	permease
HUF98_RS01790	COG1192	Involved in chromosome partitioning
HUF98_RS01830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUF98_RS01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUF98_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS01885	COG0583	DNA-binding transcription factor activity
HUF98_RS01930	COG0517	IMP dehydrogenase activity
HUF98_RS01935	COG1983	PspC domain protein
HUF98_RS01945	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS01960	COG0408	coproporphyrinogen oxidase activity
HUF98_RS01980	COG0513	Belongs to the DEAD box helicase family
HUF98_RS01990	COG1127	ABC transporter
HUF98_RS01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUF98_RS02005	COG2854	intermembrane phospholipid transfer
HUF98_RS02015	COG0598	Magnesium transport protein CorA
HUF98_RS02025	COG0494	nUDIX hydrolase
HUF98_RS02030	COG1040	competence protein
HUF98_RS02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUF98_RS02055	COG1946	Acyl-CoA thioesterase
HUF98_RS02060	COG1301	dicarboxylic acid transport
HUF98_RS02075	COG1959	2 iron, 2 sulfur cluster binding
HUF98_RS02080	COG1017	nitric oxide dioxygenase activity
HUF98_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_RS02090	COG0433	COG0433 Predicted ATPase
HUF98_RS02095	COG0626	cystathionine gamma-synthase activity
HUF98_RS02250	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HUF98_RS02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HUF98_RS02290	COG0339	signal peptide processing
HUF98_RS02295	COG0557	exoribonuclease II activity
HUF98_RS02340	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUF98_RS02345	COG2169	Transcriptional regulator
HUF98_RS02350	COG0697	spore germination
HUF98_RS02355	COG1295	ribonuclease BN
HUF98_RS02390	COG1702	phosphate starvation-inducible protein PhoH
HUF98_RS02400	COG0739	heme binding
HUF98_RS02400	COG0741	lytic transglycosylase activity
HUF98_RS02400	COG1196	nuclear chromosome segregation
HUF98_RS02430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUF98_RS02435	COG1183	phosphatidylcholine synthase activity
HUF98_RS02480	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS02485	COG1309	transcriptional regulator
HUF98_RS02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUF98_RS02505	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS02525	COG2969	positive regulation of protein catabolic process
HUF98_RS02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUF98_RS02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUF98_RS02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUF98_RS02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUF98_RS02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUF98_RS02590	COG1408	metallophosphoesterase
HUF98_RS02600	COG2199	diguanylate cyclase activity
HUF98_RS02660	COG1607	acyl-coa hydrolase
HUF98_RS02690	COG2350	Protein conserved in bacteria
HUF98_RS02700	COG0613	PHP domain protein
HUF98_RS02705	COG3781	membrane
HUF98_RS02715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUF98_RS02720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUF98_RS02730	COG1862	Preprotein translocase
HUF98_RS02765	COG2205	protein histidine kinase activity
HUF98_RS02770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUF98_RS02790	COG0726	polysaccharide deacetylase
HUF98_RS02795	COG0463	Glycosyl transferase, family 2
HUF98_RS02800	COG0438	transferase activity, transferring glycosyl groups
HUF98_RS02815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUF98_RS02865	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS02870	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS02880	COG2205	protein histidine kinase activity
HUF98_RS02885	COG0745	RESPONSE REGULATOR receiver
HUF98_RS02890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HUF98_RS02905	COG0584	glycerophosphoryl diester phosphodiesterase
HUF98_RS02910	COG2096	Adenosyltransferase
HUF98_RS02915	COG4206	TonB-dependent receptor
HUF98_RS02960	COG0285	dihydrofolate synthase activity
HUF98_RS02980	COG0450	alkyl hydroperoxide reductase
HUF98_RS02995	COG0477	Major facilitator Superfamily
HUF98_RS03000	COG1272	protein, Hemolysin III
HUF98_RS03030	COG0183	Belongs to the thiolase family
HUF98_RS03035	COG2207	Transcriptional regulator
HUF98_RS03055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_RS03075	COG0183	Belongs to the thiolase family
HUF98_RS03085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUF98_RS03085	COG2885	chlorophyll binding
HUF98_RS03095	COG1690	Belongs to the RtcB family
HUF98_RS03100	COG0833	amino acid
HUF98_RS03110	COG2233	PERMEase
HUF98_RS03115	COG1217	gtp-binding protein TYPA
HUF98_RS03140	COG2094	Belongs to the DNA glycosylase MPG family
HUF98_RS03145	COG4772	TonB-dependent receptor
HUF98_RS03150	COG1902	pentaerythritol trinitrate reductase activity
HUF98_RS03165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUF98_RS03170	COG0354	folic acid binding
HUF98_RS03180	COG3189	MarR family transcriptional regulator
HUF98_RS03185	COG2824	Alkylphosphonate utilization operon protein PhnA
HUF98_RS03190	COG3422	double-strand break repair
HUF98_RS03230	COG0840	transmembrane signaling receptor activity
HUF98_RS03250	COG5510	response to toxic substance
HUF98_RS03260	COG2832	Protein of unknown function (DUF454)
HUF98_RS03265	COG1376	ErfK ybiS ycfS ynhG family protein
HUF98_RS03305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUF98_RS03315	COG1289	transmembrane transporter activity
HUF98_RS03320	COG2814	Major facilitator Superfamily
HUF98_RS03340	COG1115	amino acid carrier protein
HUF98_RS03345	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUF98_RS03350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUF98_RS03355	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HUF98_RS03360	COG3590	peptidase
HUF98_RS03385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUF98_RS03395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUF98_RS03400	COG1077	Cell shape determining protein MreB Mrl
HUF98_RS03405	COG1792	Involved in formation and maintenance of cell shape
HUF98_RS03410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HUF98_RS03415	COG0424	maF-like protein
HUF98_RS03420	COG1530	ribonuclease E activity
HUF98_RS03430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_RS03440	COG0560	Phosphoserine phosphatase
HUF98_RS03450	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_RS03475	COG2207	Transcriptional regulator
HUF98_RS03535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUF98_RS03740	COG0582	viral genome integration into host DNA
HUF98_RS03750	COG1113	amino acid transport
HUF98_RS03755	COG2828	Protein conserved in bacteria
HUF98_RS03760	COG0142	geranyltranstransferase activity
HUF98_RS03765	COG2315	Protein conserved in bacteria
HUF98_RS03780	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUF98_RS03800	COG2194	sulfuric ester hydrolase activity
HUF98_RS03805	COG0745	RESPONSE REGULATOR receiver
HUF98_RS03810	COG0642	Histidine kinase
HUF98_RS03820	COG0004	ammonium transporteR
HUF98_RS03825	COG0583	DNA-binding transcription factor activity
HUF98_RS03850	COG0525	valine-tRNA ligase activity
HUF98_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS03870	COG0393	Putative heavy-metal-binding
HUF98_RS03875	COG0393	Putative heavy-metal-binding
HUF98_RS03880	COG1538	Outer membrane efflux protein
HUF98_RS03890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS03895	COG0671	phosphoesterase, PA-phosphatase related
HUF98_RS03925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HUF98_RS03940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUF98_RS03940	COG1648	precorrin-2 dehydrogenase activity
HUF98_RS03945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUF98_RS03950	COG1733	regulation of RNA biosynthetic process
HUF98_RS03960	COG0531	amino acid
HUF98_RS03975	COG0321	lipoyl(octanoyl) transferase activity
HUF98_RS03980	COG2921	Belongs to the UPF0250 family
HUF98_RS04020	COG2009	succinate dehydrogenase
HUF98_RS04025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HUF98_RS04030	COG1053	succinate dehydrogenase
HUF98_RS04035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUF98_RS04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUF98_RS04080	COG2354	Protein conserved in bacteria
HUF98_RS04085	COG2321	neutral zinc metallopeptidase
HUF98_RS04105	COG2843	Capsule synthesis protein
HUF98_RS04120	COG0589	response to stress
HUF98_RS04130	COG0251	oxidation-reduction process
HUF98_RS04150	COG0505	Belongs to the CarA family
HUF98_RS04180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUF98_RS04185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUF98_RS04245	COG0477	Major facilitator Superfamily
HUF98_RS04250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUF98_RS04265	COG1597	lipid kinase activity
HUF98_RS04270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUF98_RS04290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_RS04295	COG0584	glycerophosphoryl diester phosphodiesterase
HUF98_RS04315	COG0741	lytic transglycosylase activity
HUF98_RS04335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUF98_RS04350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_RS04375	COG3811	Belongs to the UPF0386 family
HUF98_RS04400	COG0778	Nitroreductase
HUF98_RS04415	COG1929	Belongs to the glycerate kinase type-1 family
HUF98_RS04420	COG0243	molybdopterin cofactor binding
HUF98_RS04425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUF98_RS04430	COG3339	Conserved Protein
HUF98_RS04440	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HUF98_RS04455	COG1115	amino acid carrier protein
HUF98_RS04460	COG1113	amino acid transport
HUF98_RS04470	COG0019	diaminopimelate decarboxylase activity
HUF98_RS04480	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS04485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUF98_RS04515	COG0463	Glycosyl transferase, family 2
HUF98_RS04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS04570	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUF98_RS04575	COG1136	(ABC) transporter
HUF98_RS04580	COG0658	competence protein
HUF98_RS04580	COG2333	competence protein COMEC
HUF98_RS04590	COG0616	signal peptide processing
HUF98_RS04590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUF98_RS04595	COG0596	Alpha beta hydrolase
HUF98_RS04600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUF98_RS04610	COG0628	permease
HUF98_RS04645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUF98_RS04665	COG0823	Involved in the tonB-independent uptake of proteins
HUF98_RS04685	COG0824	Thioesterase
HUF98_RS04690	COG1473	amidohydrolase
HUF98_RS04710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUF98_RS04710	COG0047	phosphoribosylformylglycinamidine synthase activity
HUF98_RS04715	COG2814	Major facilitator Superfamily
HUF98_RS04725	COG1024	Enoyl-CoA hydratase
HUF98_RS04730	COG1056	cytidyltransferase-related domain
HUF98_RS04730	COG1051	belongs to the nudix hydrolase family
HUF98_RS04740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUF98_RS04755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUF98_RS04770	COG4625	pathogenesis
HUF98_RS04775	COG0583	DNA-binding transcription factor activity
HUF98_RS04780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUF98_RS04785	COG4208	sulfate ABC transporter
HUF98_RS04790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUF98_RS04800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HUF98_RS04805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUF98_RS04810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUF98_RS04830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUF98_RS04840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUF98_RS04850	COG0681	Belongs to the peptidase S26 family
HUF98_RS04865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUF98_RS04875	COG1381	Involved in DNA repair and RecF pathway recombination
HUF98_RS04880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUF98_RS04890	COG4221	oxidoreductase activity
HUF98_RS04920	COG0436	Aminotransferase
HUF98_RS04940	COG0556	nucleotide-excision repair
HUF98_RS04995	COG2070	2-Nitropropane dioxygenase
HUF98_RS05025	COG1215	transferase activity, transferring glycosyl groups
HUF98_RS05040	COG0415	Belongs to the DNA photolyase family
HUF98_RS05050	COG1252	NADH dehydrogenase
HUF98_RS05055	COG1686	Belongs to the peptidase S11 family
HUF98_RS05070	COG1187	pseudouridine synthase activity
HUF98_RS05095	COG0477	Major facilitator Superfamily
HUF98_RS05100	COG0583	DNA-binding transcription factor activity
HUF98_RS05105	COG1823	symporter activity
HUF98_RS05115	COG0612	Peptidase, M16
HUF98_RS05140	COG0352	thiamine-phosphate diphosphorylase activity
HUF98_RS05175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_RS05185	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_RS05200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUF98_RS05205	COG0076	glutamate decarboxylase activity
HUF98_RS05215	COG1522	sequence-specific DNA binding
HUF98_RS05220	COG3961	Belongs to the TPP enzyme family
HUF98_RS05225	COG1113	amino acid transport
HUF98_RS05230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUF98_RS05235	COG0573	inorganic phosphate transmembrane transporter activity
HUF98_RS05245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUF98_RS05250	COG0616	signal peptide processing
HUF98_RS05285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUF98_RS05290	COG1686	Belongs to the peptidase S11 family
HUF98_RS05315	COG0583	DNA-binding transcription factor activity
HUF98_RS05320	COG1067	ATP-dependent peptidase activity
HUF98_RS05325	COG2211	Major facilitator Superfamily
HUF98_RS05345	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUF98_RS05365	COG1966	Carbon starvation protein
HUF98_RS05370	COG2879	small protein
HUF98_RS05405	COG1741	Belongs to the pirin family
HUF98_RS05415	COG2964	Protein conserved in bacteria
HUF98_RS05430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_RS05435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUF98_RS05440	COG4605	iron ion homeostasis
HUF98_RS05445	COG4604	ABC transporter, ATP-binding protein
HUF98_RS05450	COG4607	ABC-type enterochelin transport system periplasmic component
HUF98_RS05455	COG4774	siderophore transport
HUF98_RS05465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_RS05470	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUF98_RS05475	COG1535	isochorismatase
HUF98_RS05475	COG3433	isochorismatase activity
HUF98_RS05485	COG1132	(ABC) transporter
HUF98_RS05490	COG1132	(ABC) transporter
HUF98_RS05495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HUF98_RS05505	COG1169	isochorismate synthase
HUF98_RS05520	COG3739	integral membrane protein
HUF98_RS05540	COG0302	gtp cyclohydrolase
HUF98_RS05550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUF98_RS05585	COG0512	Glutamine amidotransferase of anthranilate synthase
HUF98_RS05600	COG0174	glutamine synthetase
HUF98_RS05610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUF98_RS05645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUF98_RS05650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUF98_RS05655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUF98_RS05675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUF98_RS05680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUF98_RS05685	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUF98_RS05700	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS05705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUF98_RS05710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUF98_RS05720	COG2223	nitrite transmembrane transporter activity
HUF98_RS05730	COG0024	Methionine aminopeptidase
HUF98_RS05735	COG0052	Belongs to the universal ribosomal protein uS2 family
HUF98_RS05750	COG2207	Transcriptional regulator
HUF98_RS05775	COG2951	lytic endotransglycosylase activity
HUF98_RS05780	COG0772	Belongs to the SEDS family
HUF98_RS05795	COG0842	Transport permease protein
HUF98_RS05800	COG1131	(ABC) transporter
HUF98_RS05845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS05860	COG4215	(ABC) transporter
HUF98_RS05865	COG4160	amino acid transport
HUF98_RS05870	COG4598	ABC transporter
HUF98_RS05880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUF98_RS05885	COG0826	peptidase U32
HUF98_RS05890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_RS05905	COG1720	tRNA m6t6A37 methyltransferase activity
HUF98_RS05915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUF98_RS05930	COG0642	Histidine kinase
HUF98_RS05940	COG0494	nUDIX hydrolase
HUF98_RS05950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUF98_RS05955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUF98_RS05960	COG3139	Protein of unknown function (DUF1315)
HUF98_RS05965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUF98_RS05970	COG1301	dicarboxylic acid transport
HUF98_RS05975	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS05980	COG2819	hydrolase of the alpha beta superfamily
HUF98_RS05990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUF98_RS06000	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUF98_RS06005	COG1234	tRNA 3'-trailer cleavage
HUF98_RS06035	COG2363	Small membrane protein
HUF98_RS06060	COG0513	Belongs to the DEAD box helicase family
HUF98_RS06070	COG0778	Nitroreductase
HUF98_RS06100	COG1286	toxin biosynthetic process
HUF98_RS06125	COG4783	chaperone-mediated protein folding
HUF98_RS06130	COG1610	YqeY-like protein
HUF98_RS06160	COG0515	serine threonine protein kinase
HUF98_RS06160	COG2815	serine threonine protein kinase
HUF98_RS06230	COG3111	PFAM Bacterial OB fold (BOF) protein
HUF98_RS06255	COG3243	poly(R)-hydroxyalkanoic acid synthase
HUF98_RS06260	COG0786	glutamate:sodium symporter activity
HUF98_RS06270	COG2186	Transcriptional regulator
HUF98_RS06320	COG0477	Major facilitator Superfamily
HUF98_RS06345	COG2985	domain, Protein
HUF98_RS06355	COG2995	paraquat-inducible protein a
HUF98_RS06360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUF98_RS06360	COG3008	intermembrane lipid transfer
HUF98_RS06370	COG2351	hydroxyisourate hydrolase activity
HUF98_RS06410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUF98_RS06420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUF98_RS06425	COG0642	Histidine kinase
HUF98_RS06430	COG0745	RESPONSE REGULATOR receiver
HUF98_RS06450	COG1794	racemase activity, acting on amino acids and derivatives
HUF98_RS06480	COG1301	dicarboxylic acid transport
HUF98_RS06490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_RS06495	COG2011	ABC-type metal ion transport system permease component
HUF98_RS06500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUF98_RS06505	COG1464	Belongs to the NlpA lipoprotein family
HUF98_RS06510	COG0151	Belongs to the GarS family
HUF98_RS06515	COG0138	bifunctional purine biosynthesis protein purh
HUF98_RS06520	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HUF98_RS06550	COG2308	Evidence 4 Homologs of previously reported genes of
HUF98_RS06560	COG1305	Transglutaminase-like
HUF98_RS06570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUF98_RS06575	COG0305	Participates in initiation and elongation during chromosome replication
HUF98_RS06600	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUF98_RS06610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUF98_RS06615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUF98_RS06640	COG0726	polysaccharide deacetylase
HUF98_RS06640	COG1649	PFAM Uncharacterised BCR, COG1649
HUF98_RS06645	COG1215	transferase activity, transferring glycosyl groups
HUF98_RS06650	COG3658	cytochrome
HUF98_RS06660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUF98_RS06675	COG0583	DNA-binding transcription factor activity
HUF98_RS06705	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS06710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUF98_RS06715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_RS06740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUF98_RS06745	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUF98_RS06755	COG2205	protein histidine kinase activity
HUF98_RS06760	COG0745	RESPONSE REGULATOR receiver
HUF98_RS06765	COG0174	glutamine synthetase
HUF98_RS06785	COG0729	surface antigen
HUF98_RS06810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUF98_RS06815	COG2814	Major facilitator Superfamily
HUF98_RS06830	COG0583	DNA-binding transcription factor activity
HUF98_RS06845	COG1187	pseudouridine synthase activity
HUF98_RS06865	COG0802	atpase or kinase
HUF98_RS06870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUF98_RS06880	COG1923	regulation of RNA biosynthetic process
HUF98_RS06885	COG0697	spore germination
HUF98_RS06910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUF98_RS06915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUF98_RS06915	COG0519	Catalyzes the synthesis of GMP from XMP
HUF98_RS06920	COG4302	ethanolamine ammonia-lyase activity
HUF98_RS06925	COG4303	Ethanolamine ammonia lyase large subunit
HUF98_RS06930	COG0531	amino acid
HUF98_RS06950	COG1454	alcohol dehydrogenase
HUF98_RS06955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUF98_RS06980	COG0308	aminopeptidase N
HUF98_RS07020	COG1605	Chorismate mutase
HUF98_RS07050	COG0668	transmembrane transport
HUF98_RS07080	COG4773	Receptor
HUF98_RS07100	COG0488	(ABC) transporter
HUF98_RS07105	COG0589	response to stress
HUF98_RS07130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUF98_RS07140	COG3135	benzoate transporter
HUF98_RS07145	COG1522	sequence-specific DNA binding
HUF98_RS07155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUF98_RS07160	COG0583	DNA-binding transcription factor activity
HUF98_RS07170	COG0183	Belongs to the thiolase family
HUF98_RS07180	COG2030	dehydratase
HUF98_RS07185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUF98_RS07200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUF98_RS07215	COG0824	Thioesterase
HUF98_RS07220	COG1454	alcohol dehydrogenase
HUF98_RS07230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUF98_RS07250	COG0069	glutamate synthase activity
HUF98_RS07540	COG1598	PFAM Uncharacterised protein family UPF0150
HUF98_RS07640	COG2814	Major facilitator Superfamily
HUF98_RS07655	COG0511	ligase activity, forming carbon-carbon bonds
HUF98_RS07675	COG1116	anion transmembrane transporter activity
HUF98_RS07675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUF98_RS07680	COG0745	RESPONSE REGULATOR receiver
HUF98_RS07690	COG2146	nitrite reductase [NAD(P)H] activity
HUF98_RS07690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_RS07695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_RS07700	COG0243	molybdopterin cofactor binding
HUF98_RS07710	COG0243	molybdopterin cofactor binding
HUF98_RS07715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUF98_RS07730	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUF98_RS07730	COG0315	cyclic pyranopterin monophosphate synthase activity
HUF98_RS07735	COG0303	'Molybdopterin
HUF98_RS07745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_RS07750	COG0697	spore germination
HUF98_RS07770	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HUF98_RS07775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUF98_RS07830	COG2204	response regulator
HUF98_RS07835	COG3852	Histidine kinase
HUF98_RS07860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUF98_RS07865	COG0575	Belongs to the CDS family
HUF98_RS07880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUF98_RS07900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUF98_RS07915	COG2137	regulation of response to DNA damage stimulus
HUF98_RS07925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUF98_RS07930	COG1011	Hydrolase
HUF98_RS07965	COG1522	sequence-specific DNA binding
HUF98_RS07975	COG1113	amino acid transport
HUF98_RS07995	COG0659	secondary active sulfate transmembrane transporter activity
HUF98_RS08000	COG2135	peptidase activity
HUF98_RS08015	COG3300	MHYT domain
HUF98_RS08015	COG5001	Diguanylate cyclase
HUF98_RS08140	COG2369	cell adhesion
HUF98_RS08145	COG4383	Mu-like prophage protein gp29
HUF98_RS08165	COG4373	Mu-like prophage FluMu protein gp28
HUF98_RS08225	COG0776	regulation of translation
HUF98_RS08285	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUF98_RS08285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUF98_RS08285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUF98_RS08290	COG1105	Belongs to the carbohydrate kinase PfkB family
HUF98_RS08295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUF98_RS08295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUF98_RS08325	COG0024	Methionine aminopeptidase
HUF98_RS08330	COG0583	DNA-binding transcription factor activity
HUF98_RS08340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUF98_RS08345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUF98_RS08350	COG0516	GMP reductase activity
HUF98_RS08350	COG0517	IMP dehydrogenase activity
HUF98_RS08380	COG0552	protein localization to endoplasmic reticulum
HUF98_RS08390	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HUF98_RS08405	COG4890	Cyd operon protein YbgT
HUF98_RS08410	COG1294	oxidase, subunit
HUF98_RS08425	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUF98_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUF98_RS08440	COG4774	siderophore transport
HUF98_RS08455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUF98_RS08460	COG0569	domain protein
HUF98_RS08465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUF98_RS08495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUF98_RS08500	COG0542	response to heat
HUF98_RS08525	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUF98_RS08525	COG1902	pentaerythritol trinitrate reductase activity
HUF98_RS08570	COG2323	membrane
HUF98_RS08575	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HUF98_RS08585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUF98_RS08590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUF98_RS08595	COG0183	Belongs to the thiolase family
HUF98_RS08600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUF98_RS08605	COG0596	Alpha beta hydrolase
HUF98_RS08610	COG2271	Major facilitator Superfamily
HUF98_RS08615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUF98_RS08620	COG3485	protocatechuate 3,4-dioxygenase
HUF98_RS08625	COG3485	protocatechuate 3,4-dioxygenase
HUF98_RS08630	COG0710	3-dehydroquinate dehydratase activity
HUF98_RS08635	COG3420	alginic acid biosynthetic process
HUF98_RS08640	COG3659	wide pore channel activity
HUF98_RS08645	COG4993	Dehydrogenase
HUF98_RS08655	COG2391	methyltransferase activity
HUF98_RS08670	COG1414	Transcriptional regulator
HUF98_RS08675	COG0583	DNA-binding transcription factor activity
HUF98_RS08680	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS08705	COG2814	Major facilitator Superfamily
HUF98_RS08715	COG0154	amidase activity
HUF98_RS08735	COG4638	Rieske (2fe-2S)
HUF98_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS08755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_RS08765	COG3733	amine oxidase
HUF98_RS08775	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS08785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUF98_RS08790	COG0183	Belongs to the thiolase family
HUF98_RS08795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUF98_RS08800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUF98_RS08810	COG4829	muconolactone delta-isomerase
HUF98_RS08815	COG4948	Mandelate Racemase Muconate Lactonizing
HUF98_RS08820	COG0583	DNA-binding transcription factor activity
HUF98_RS08830	COG2186	Transcriptional regulator
HUF98_RS08850	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS08865	COG1902	pentaerythritol trinitrate reductase activity
HUF98_RS08865	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUF98_RS08880	COG0789	Transcriptional regulator
HUF98_RS08905	COG1309	transcriptional regulator
HUF98_RS08910	COG0583	DNA-binding transcription factor activity
HUF98_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS08935	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS08945	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_RS09010	COG2188	Transcriptional regulator
HUF98_RS09025	COG0583	DNA-binding transcription factor activity
HUF98_RS09050	COG1566	PFAM secretion protein HlyD family protein
HUF98_RS09065	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS09070	COG0129	dihydroxy-acid dehydratase activity
HUF98_RS09080	COG0583	DNA-binding transcription factor activity
HUF98_RS09085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUF98_RS09095	COG2084	Dehydrogenase
HUF98_RS09100	COG2207	Transcriptional regulator
HUF98_RS09105	COG1064	alcohol dehydrogenase
HUF98_RS09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUF98_RS09120	COG1120	ATPase activity
HUF98_RS09140	COG0657	acetylesterase activity
HUF98_RS09155	COG1309	transcriptional regulator
HUF98_RS09165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUF98_RS09215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUF98_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS09275	COG2207	Transcriptional regulator
HUF98_RS09285	COG2205	protein histidine kinase activity
HUF98_RS09290	COG0745	RESPONSE REGULATOR receiver
HUF98_RS09295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS09300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUF98_RS09400	COG3539	Fimbrial protein
HUF98_RS09425	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUF98_RS09435	COG0753	catalase activity
HUF98_RS09450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUF98_RS09510	COG1535	isochorismatase
HUF98_RS09510	COG3433	isochorismatase activity
HUF98_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS09520	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HUF98_RS09525	COG4149	molybdate abc transporter
HUF98_RS09530	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUF98_RS09540	COG4638	Rieske (2fe-2S)
HUF98_RS09545	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HUF98_RS09550	COG0543	2 iron, 2 sulfur cluster binding
HUF98_RS09550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_RS09565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_RS09575	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS09590	COG2207	Transcriptional regulator
HUF98_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS09600	COG2610	gluconate transmembrane transporter activity
HUF98_RS09610	COG0583	DNA-binding transcription factor activity
HUF98_RS09625	COG2031	fatty acid transporter
HUF98_RS09630	COG0183	Belongs to the thiolase family
HUF98_RS09635	COG0583	DNA-binding transcription factor activity
HUF98_RS09640	COG0583	DNA-binding transcription factor activity
HUF98_RS09655	COG1027	Aspartate ammonia-lyase
HUF98_RS09665	COG0477	Major facilitator Superfamily
HUF98_RS09685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUF98_RS09690	COG4521	taurine ABC transporter
HUF98_RS09705	COG2188	Transcriptional regulator
HUF98_RS09715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUF98_RS09720	COG1733	regulation of RNA biosynthetic process
HUF98_RS09725	COG2207	Transcriptional regulator
HUF98_RS09725	COG3708	Transcriptional regulator
HUF98_RS09740	COG0730	response to heat
HUF98_RS09755	COG3453	Protein conserved in bacteria
HUF98_RS09755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_RS09765	COG3781	membrane
HUF98_RS09770	COG1063	alcohol dehydrogenase
HUF98_RS09780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUF98_RS09785	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUF98_RS09790	COG0022	dehydrogenase e1 component
HUF98_RS09795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUF98_RS09800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUF98_RS09815	COG3706	GGDEF domain
HUF98_RS09830	COG0133	tryptophan synthase activity
HUF98_RS09840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUF98_RS09875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUF98_RS09900	COG2226	methyltransferase
HUF98_RS09955	COG0842	Transport permease protein
HUF98_RS09960	COG0842	Transport permease protein
HUF98_RS09965	COG1131	(ABC) transporter
HUF98_RS09980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUF98_RS09985	COG4773	Receptor
HUF98_RS10005	COG0730	response to heat
HUF98_RS10010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUF98_RS10025	COG0406	alpha-ribazole phosphatase activity
HUF98_RS10030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUF98_RS10045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUF98_RS10075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUF98_RS10085	COG4264	IucA IucC family
HUF98_RS10090	COG4264	IucA IucC family
HUF98_RS10110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUF98_RS10125	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS10130	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS10135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUF98_RS10140	COG2207	Transcriptional regulator
HUF98_RS10145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUF98_RS10150	COG0776	regulation of translation
HUF98_RS10175	COG0822	iron-sulfur transferase activity
HUF98_RS10180	COG0316	Belongs to the HesB IscA family
HUF98_RS10210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUF98_RS10230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUF98_RS10235	COG0702	epimerase
HUF98_RS10270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUF98_RS10280	COG0339	signal peptide processing
HUF98_RS10290	COG4166	transmembrane transport
HUF98_RS10325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUF98_RS10330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUF98_RS10360	COG0776	regulation of translation
HUF98_RS10425	COG0084	hydrolase, TatD family'
HUF98_RS10445	COG1663	tetraacyldisaccharide 4'-kinase activity
HUF98_RS10450	COG1132	(ABC) transporter
HUF98_RS10460	COG0811	peptide transport
HUF98_RS10465	COG1475	DNA binding
HUF98_RS10470	COG1192	Involved in chromosome partitioning
HUF98_RS10480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUF98_RS10495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUF98_RS10500	COG0191	fructose-bisphosphate aldolase activity
HUF98_RS10520	COG0424	maF-like protein
HUF98_RS10525	COG2850	peptidyl-arginine hydroxylation
HUF98_RS10535	COG0640	Transcriptional regulator
HUF98_RS10545	COG3619	membrane
HUF98_RS10550	COG3122	Protein conserved in bacteria
HUF98_RS10555	COG1132	(ABC) transporter
HUF98_RS10575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUF98_RS10580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUF98_RS10590	COG0506	proline dehydrogenase activity
HUF98_RS10590	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUF98_RS10590	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUF98_RS10595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUF98_RS10610	COG3698	Phosphodiester glycosidase
HUF98_RS10620	COG2353	YceI-like domain
HUF98_RS10630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUF98_RS10675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUF98_RS10675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUF98_RS10700	COG3539	Fimbrial protein
HUF98_RS10705	COG3121	Chaperone
HUF98_RS10735	COG0697	spore germination
HUF98_RS10745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUF98_RS10755	COG0583	DNA-binding transcription factor activity
HUF98_RS10790	COG1522	sequence-specific DNA binding
HUF98_RS10800	COG1126	abc transporter atp-binding protein
HUF98_RS10805	COG0765	amino acid transport
HUF98_RS10810	COG0765	amino acid transport
HUF98_RS10840	COG1464	Belongs to the NlpA lipoprotein family
HUF98_RS10850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUF98_RS10855	COG2011	ABC-type metal ion transport system permease component
HUF98_RS10860	COG0012	GTP binding
HUF98_RS10885	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HUF98_RS10925	COG0386	Belongs to the glutathione peroxidase family
HUF98_RS10935	COG0436	Aminotransferase
HUF98_RS10940	COG1301	dicarboxylic acid transport
HUF98_RS10975	COG3634	alkyl hydroperoxide reductase activity
HUF98_RS10990	COG0583	DNA-binding transcription factor activity
HUF98_RS10995	COG0798	PFAM Bile acid sodium symporter
HUF98_RS11000	COG0640	Transcriptional regulator
HUF98_RS11015	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUF98_RS11025	COG0583	DNA-binding transcription factor activity
HUF98_RS11035	COG1953	Uracil, thiamine, allantoin
HUF98_RS11045	COG2175	clavaminate synthase activity
HUF98_RS11050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUF98_RS11055	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUF98_RS11060	COG4521	taurine ABC transporter
HUF98_RS11070	COG0477	Major facilitator Superfamily
HUF98_RS11090	COG1271	oxidase subunit
HUF98_RS11095	COG1294	oxidase, subunit
HUF98_RS11105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_RS11125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUF98_RS11145	COG3052	prosthetic group binding
HUF98_RS11150	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HUF98_RS11160	COG0583	DNA-binding transcription factor activity
HUF98_RS11170	COG2814	Major facilitator Superfamily
HUF98_RS11190	COG1346	cytolysis
HUF98_RS11200	COG0583	DNA-binding transcription factor activity
HUF98_RS11205	COG0625	glutathione transferase activity
HUF98_RS11210	COG0625	glutathione transferase activity
HUF98_RS11215	COG0583	DNA-binding transcription factor activity
HUF98_RS11230	COG1045	serine acetyltransferase
HUF98_RS11235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUF98_RS11240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUF98_RS11250	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUF98_RS11265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUF98_RS11270	COG1126	abc transporter atp-binding protein
HUF98_RS11275	COG0765	amino acid transport
HUF98_RS11280	COG0765	amino acid transport
HUF98_RS11300	COG0784	Response regulator, receiver
HUF98_RS11300	COG2205	protein histidine kinase activity
HUF98_RS11320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUF98_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS11395	COG0583	DNA-binding transcription factor activity
HUF98_RS11415	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_RS11420	COG1309	transcriptional regulator
HUF98_RS11425	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS11430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUF98_RS11435	COG1024	Enoyl-CoA hydratase
HUF98_RS11440	COG4770	biotin carboxylase activity
HUF98_RS11450	COG0583	DNA-binding transcription factor activity
HUF98_RS11465	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS11475	COG2814	Major facilitator Superfamily
HUF98_RS11485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUF98_RS11490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUF98_RS11495	COG2814	Major facilitator Superfamily
HUF98_RS11500	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS11505	COG1024	Enoyl-CoA hydratase
HUF98_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS11515	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUF98_RS11520	COG0183	Belongs to the thiolase family
HUF98_RS11535	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS11540	COG2192	nodulation
HUF98_RS11555	COG1024	Enoyl-CoA hydratase
HUF98_RS11570	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS11575	COG2814	Major facilitator Superfamily
HUF98_RS11580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUF98_RS11585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HUF98_RS11600	COG3842	ATPase activity
HUF98_RS11605	COG1840	ABC-type Fe3 transport system, periplasmic component
HUF98_RS11615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_RS11630	COG0583	DNA-binding transcription factor activity
HUF98_RS11635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUF98_RS11640	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS11650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUF98_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS11665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUF98_RS11670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_RS11675	COG2267	carboxylic ester hydrolase activity
HUF98_RS11695	COG3038	cytochrome b561
HUF98_RS11700	COG0753	catalase activity
HUF98_RS11705	COG2271	Major facilitator Superfamily
HUF98_RS11710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUF98_RS11715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUF98_RS11730	COG2207	Transcriptional regulator
HUF98_RS11745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUF98_RS11775	COG2050	protein possibly involved in aromatic compounds catabolism
HUF98_RS11785	COG3327	negative regulation of DNA-templated transcription, initiation
HUF98_RS11795	COG0183	Belongs to the thiolase family
HUF98_RS11800	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUF98_RS11805	COG1024	Enoyl-CoA hydratase
HUF98_RS11810	COG1024	Enoyl-CoA hydratase
HUF98_RS11815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_RS11820	COG2151	metal-sulfur cluster biosynthetic enzyme
HUF98_RS11825	COG3396	Phenylacetate-CoA oxygenase
HUF98_RS11830	COG3460	Phenylacetate-CoA oxygenase
HUF98_RS11835	COG3396	Phenylacetate-CoA oxygenase
HUF98_RS11840	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS11840	COG2030	dehydratase
HUF98_RS11845	COG1760	l-serine dehydratase
HUF98_RS11850	COG0531	amino acid
HUF98_RS11855	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS11880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUF98_RS11900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_RS11910	COG0789	Transcriptional regulator
HUF98_RS11920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUF98_RS11935	COG2807	transmembrane transport
HUF98_RS11940	COG0590	tRNA wobble adenosine to inosine editing
HUF98_RS12100	COG1116	anion transmembrane transporter activity
HUF98_RS12105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUF98_RS12115	COG0864	Transcriptional regulator
HUF98_RS12125	COG1733	regulation of RNA biosynthetic process
HUF98_RS12130	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_RS12135	COG0439	Biotin carboxylase
HUF98_RS12150	COG1063	alcohol dehydrogenase
HUF98_RS12160	COG1309	transcriptional regulator
HUF98_RS12170	COG0038	chloride channel
HUF98_RS12175	COG4770	biotin carboxylase activity
HUF98_RS12195	COG1914	H( )-stimulated, divalent metal cation uptake system
HUF98_RS12200	COG0583	DNA-binding transcription factor activity
HUF98_RS12230	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUF98_RS12255	COG3293	Transposase
HUF98_RS12270	COG1560	Kdo2-lipid A biosynthetic process
HUF98_RS12280	COG5006	permease, DMT superfamily
HUF98_RS12285	COG1522	sequence-specific DNA binding
HUF98_RS12300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HUF98_RS12310	COG4122	O-methyltransferase activity
HUF98_RS12340	COG1538	Outer membrane efflux protein
HUF98_RS12345	COG1137	ATPase activity
HUF98_RS12350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HUF98_RS12360	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUF98_RS12365	COG0517	IMP dehydrogenase activity
HUF98_RS12365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUF98_RS12400	COG2814	Major facilitator Superfamily
HUF98_RS12435	COG1278	Cold shock
HUF98_RS12440	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS12470	COG1570	exodeoxyribonuclease VII activity
HUF98_RS12520	COG0583	DNA-binding transcription factor activity
HUF98_RS12530	COG4638	Rieske (2fe-2S)
HUF98_RS12540	COG0543	2 iron, 2 sulfur cluster binding
HUF98_RS12540	COG0633	Ferredoxin
HUF98_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS12550	COG3135	benzoate transporter
HUF98_RS12555	COG2814	Major facilitator Superfamily
HUF98_RS12570	COG1643	Atp-dependent helicase
HUF98_RS12575	COG0450	alkyl hydroperoxide reductase
HUF98_RS12585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUF98_RS12595	COG3634	alkyl hydroperoxide reductase activity
HUF98_RS12615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUF98_RS12620	COG0625	glutathione transferase activity
HUF98_RS12630	COG2885	chlorophyll binding
HUF98_RS12665	COG0542	response to heat
HUF98_RS12680	COG1765	OsmC-like protein
HUF98_RS12705	COG0667	Aldo Keto reductase
HUF98_RS12720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUF98_RS12730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUF98_RS12740	COG0527	aspartate kinase activity
HUF98_RS12750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUF98_RS12760	COG3038	cytochrome b561
HUF98_RS12765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUF98_RS12770	COG2252	PERMEase
HUF98_RS12780	COG2072	flavoprotein involved in K transport
HUF98_RS12795	COG1741	Belongs to the pirin family
HUF98_RS12800	COG1309	transcriptional regulator
HUF98_RS12810	COG0300	oxidoreductase activity
HUF98_RS12815	COG2072	flavoprotein involved in K transport
HUF98_RS12820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUF98_RS12865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUF98_RS12880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_RS12900	COG1024	Enoyl-CoA hydratase
HUF98_RS12905	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS12915	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS12940	COG0697	spore germination
HUF98_RS12985	COG1113	amino acid transport
HUF98_RS13005	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS13025	COG0531	amino acid
HUF98_RS13035	COG1113	amino acid transport
HUF98_RS13075	COG4269	membrane
HUF98_RS13090	COG1309	transcriptional regulator
HUF98_RS13095	COG3328	transposase activity
HUF98_RS13120	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUF98_RS13150	COG3152	Membrane
HUF98_RS13200	COG0582	viral genome integration into host DNA
HUF98_RS13210	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUF98_RS13210	COG1902	pentaerythritol trinitrate reductase activity
HUF98_RS13220	COG2203	Gaf domain
HUF98_RS13220	COG3706	GGDEF domain
HUF98_RS13220	COG5001	Diguanylate cyclase
HUF98_RS13220	COG4251	negative regulation of phosphorylation
HUF98_RS13230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUF98_RS13260	COG4172	Belongs to the ABC transporter superfamily
HUF98_RS13265	COG4239	(ABC) transporter, permease
HUF98_RS13270	COG4174	ABC transporter (Permease)
HUF98_RS13280	COG1388	LysM domain
HUF98_RS13280	COG1388	LysM domain
HUF98_RS13280	COG0741	lytic transglycosylase activity
HUF98_RS13280	COG0741	lytic transglycosylase activity
HUF98_RS13285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUF98_RS13325	COG0583	DNA-binding transcription factor activity
HUF98_RS13330	COG1279	arginine transmembrane transporter activity
HUF98_RS13350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_RS13355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_RS13360	COG0006	proline dipeptidase activity
HUF98_RS13395	COG2194	sulfuric ester hydrolase activity
HUF98_RS13680	COG3620	sequence-specific DNA binding
HUF98_RS13745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUF98_RS13765	COG3384	dioxygenase
HUF98_RS13775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUF98_RS13780	COG2878	Part of a membrane complex involved in electron transport
HUF98_RS13785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUF98_RS13810	COG0768	penicillin binding
HUF98_RS13815	COG0742	ribosomal rna small subunit methyltransferase
HUF98_RS13830	COG0830	nickel cation binding
HUF98_RS13840	COG0804	urea catabolic process
HUF98_RS13885	COG1253	flavin adenine dinucleotide binding
HUF98_RS13890	COG2851	Citrate transporter
HUF98_RS13940	COG1773	rubredoxin
HUF98_RS13945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_RS13955	COG0583	DNA-binding transcription factor activity
HUF98_RS13985	COG4181	ATPase activity
HUF98_RS14010	COG4771	TonB-dependent receptor
HUF98_RS14030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUF98_RS14050	COG0306	phosphate transporter
HUF98_RS14075	COG2223	nitrite transmembrane transporter activity
HUF98_RS14080	COG2207	Transcriptional regulator
HUF98_RS14085	COG2066	Belongs to the glutaminase family
HUF98_RS14095	COG0477	Major facilitator Superfamily
HUF98_RS14105	COG0028	Belongs to the TPP enzyme family
HUF98_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS14125	COG2267	carboxylic ester hydrolase activity
HUF98_RS14135	COG2271	Major facilitator Superfamily
HUF98_RS14170	COG1414	Transcriptional regulator
HUF98_RS14185	COG1024	Enoyl-CoA hydratase
HUF98_RS14195	COG1215	transferase activity, transferring glycosyl groups
HUF98_RS14200	COG1649	PFAM Uncharacterised BCR, COG1649
HUF98_RS14200	COG0726	polysaccharide deacetylase
HUF98_RS14210	COG4681	YaeQ
HUF98_RS14220	COG0523	cobalamin synthesis protein
HUF98_RS14230	COG1607	acyl-coa hydrolase
HUF98_RS14240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUF98_RS14245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUF98_RS14250	COG1309	transcriptional regulator
HUF98_RS14275	COG2040	homocysteine
HUF98_RS14280	COG0531	amino acid
HUF98_RS14305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_RS14310	COG0477	Major facilitator Superfamily
HUF98_RS14350	COG0405	Gamma-glutamyltransferase
HUF98_RS14355	COG2814	Major facilitator Superfamily
HUF98_RS14365	COG2050	protein possibly involved in aromatic compounds catabolism
HUF98_RS14380	COG1090	epimerase
HUF98_RS14400	COG0420	3'-5' exonuclease activity
HUF98_RS14425	COG0735	belongs to the Fur family
HUF98_RS14430	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUF98_RS14450	COG0121	glutamine amidotransferase
HUF98_RS14465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUF98_RS14475	COG0210	DNA helicase
HUF98_RS14480	COG2885	chlorophyll binding
HUF98_RS14485	COG0204	Acyl-transferase
HUF98_RS14500	COG2894	cell division
HUF98_RS14515	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS14520	COG1674	ftsk spoiiie
HUF98_RS14520	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUF98_RS14525	COG0492	ferredoxin-NADP+ reductase activity
HUF98_RS14530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HUF98_RS14540	COG0456	acetyltransferase
HUF98_RS14585	COG1981	membrane
HUF98_RS14600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUF98_RS14600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUF98_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_RS14630	COG0657	acetylesterase activity
HUF98_RS14640	COG0473	3-isopropylmalate dehydrogenase activity
HUF98_RS14645	COG0583	DNA-binding transcription factor activity
HUF98_RS14665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUF98_RS14700	COG0358	DNA primase activity
HUF98_RS14715	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HUF98_RS14745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUF98_RS14775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUF98_RS14785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUF98_RS14785	COG0351	phosphomethylpyrimidine kinase
HUF98_RS14785	COG0352	thiamine-phosphate diphosphorylase activity
HUF98_RS14790	COG1652	LysM domain
HUF98_RS14815	COG1399	metal-binding, possibly nucleic acid-binding protein
HUF98_RS14820	COG3101	peptidyl-lysine hydroxylation
HUF98_RS14825	COG0009	L-threonylcarbamoyladenylate synthase
HUF98_RS14830	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUF98_RS14835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUF98_RS14850	COG4106	trans-aconitate 2-methyltransferase activity
HUF98_RS14865	COG0596	Alpha beta hydrolase
HUF98_RS14865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUF98_RS14865	COG2226	methyltransferase
HUF98_RS14870	COG1877	trehalose-phosphatase activity
HUF98_RS14875	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUF98_RS14880	COG2223	nitrite transmembrane transporter activity
HUF98_RS14900	COG1196	nuclear chromosome segregation
HUF98_RS14910	COG0730	response to heat
HUF98_RS14925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUF98_RS14935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUF98_RS14985	COG0489	protein tyrosine kinase activity
HUF98_RS14995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUF98_RS14995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUF98_RS15025	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUF98_RS15030	COG2081	HI0933 family
HUF98_RS15040	COG0668	transmembrane transport
HUF98_RS15060	COG0583	DNA-binding transcription factor activity
HUF98_RS15080	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUF98_RS15085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUF98_RS15115	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUF98_RS15155	COG0745	RESPONSE REGULATOR receiver
HUF98_RS15175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUF98_RS15185	COG0384	phenazine biosynthesis protein PhzF
HUF98_RS15220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_RS15235	COG0583	DNA-binding transcription factor activity
HUF98_RS15265	COG0583	DNA-binding transcription factor activity
HUF98_RS15280	COG0583	DNA-binding transcription factor activity
HUF98_RS15285	COG1053	succinate dehydrogenase
HUF98_RS15295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUF98_RS15300	COG2814	Major facilitator Superfamily
HUF98_RS15305	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS15310	COG0583	DNA-binding transcription factor activity
HUF98_RS15315	COG1063	alcohol dehydrogenase
HUF98_RS15345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUF98_RS15350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUF98_RS15355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUF98_RS15370	COG3667	copper resistance
HUF98_RS15375	COG2132	Multicopper oxidase
HUF98_RS15385	COG0561	phosphatase activity
HUF98_RS15390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUF98_RS15400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUF98_RS15415	COG1214	PFAM Peptidase M22, glycoprotease
HUF98_RS15465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUF98_RS15475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUF98_RS15480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUF98_RS15485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUF98_RS15545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUF98_RS15555	COG1846	Transcriptional regulator
HUF98_RS15560	COG1764	response to oxidative stress
HUF98_RS15600	COG0037	tRNA processing
HUF98_RS15610	COG0248	Ppx GppA phosphatase
HUF98_RS15640	COG0072	phenylalanine-tRNA ligase activity
HUF98_RS15685	COG1238	metal cluster binding
HUF98_RS15690	COG0625	glutathione transferase activity
HUF98_RS15705	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_RS15710	COG3028	Belongs to the UPF0307 family
HUF98_RS15715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUF98_RS15735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUF98_RS15740	COG0617	tRNA 3'-terminal CCA addition
HUF98_RS15745	COG1555	photosystem II stabilization
HUF98_RS15750	COG3956	TIGRFAM MazG family protein
HUF98_RS15760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUF98_RS15780	COG0784	Response regulator, receiver
HUF98_RS15780	COG2205	protein histidine kinase activity
HUF98_RS15780	COG5002	protein histidine kinase activity
HUF98_RS15785	COG1024	Enoyl-CoA hydratase
HUF98_RS15790	COG2084	Dehydrogenase
HUF98_RS15795	COG3622	Belongs to the hyi family
HUF98_RS15830	COG0697	spore germination
HUF98_RS15840	COG2814	Major facilitator Superfamily
HUF98_RS15860	COG2132	Multicopper oxidase
HUF98_RS15875	COG2205	protein histidine kinase activity
HUF98_RS15905	COG0488	(ABC) transporter
HUF98_RS15995	COG2826	transposase and inactivated derivatives, IS30 family
HUF98_RS16005	COG2826	transposase and inactivated derivatives, IS30 family
HUF98_RS16075	COG1132	(ABC) transporter
HUF98_RS16125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUF98_RS16150	COG3293	Transposase
HUF98_RS16195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS16205	COG1683	Conserved Protein
HUF98_RS16245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS16255	COG1683	Conserved Protein
HUF98_RS16295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS16305	COG1683	Conserved Protein
HUF98_RS16355	COG0583	DNA-binding transcription factor activity
HUF98_RS16370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUF98_RS16515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUF98_RS16525	COG0583	DNA-binding transcription factor activity
HUF98_RS16535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUF98_RS16545	COG0084	hydrolase, TatD family'
HUF98_RS16560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUF98_RS16590	COG0440	acetolactate synthase activity
HUF98_RS16595	COG0028	Belongs to the TPP enzyme family
HUF98_RS16620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_RS16625	COG1136	(ABC) transporter
HUF98_RS16625	COG0577	efflux transmembrane transporter activity
HUF98_RS16630	COG1538	Outer membrane efflux protein
HUF98_RS16645	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUF98_RS16650	COG1162	GTPase activity
HUF98_RS16660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUF98_RS16680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUF98_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS16725	COG2986	histidine ammonia-lyase
HUF98_RS16735	COG1216	Glycosyl transferase, family 2
HUF98_RS16740	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_RS16750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUF98_RS16795	COG1426	Protein conserved in bacteria
HUF98_RS16830	COG0793	Belongs to the peptidase S41A family
HUF98_RS16845	COG2267	carboxylic ester hydrolase activity
HUF98_RS16860	COG3265	gluconokinase activity
HUF98_RS16870	COG0800	Aldolase
HUF98_RS16880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUF98_RS16885	COG0857	belongs to the CobB CobQ family
HUF98_RS16885	COG0280	phosphate acetyltransferase
HUF98_RS16890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUF98_RS16890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUF98_RS16910	COG0740	serine-type endopeptidase activity
HUF98_RS16920	COG4774	siderophore transport
HUF98_RS16930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUF98_RS16940	COG2813	Specifically methylates the guanine in position
HUF98_RS16940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUF98_RS17040	COG0788	formyltetrahydrofolate deformylase activity
HUF98_RS17065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUF98_RS17065	COG4651	solute:proton antiporter activity
HUF98_RS17085	COG0724	RNA recognition motif
HUF98_RS17090	COG0210	DNA helicase
HUF98_RS17115	COG1733	regulation of RNA biosynthetic process
HUF98_RS17125	COG2900	Belongs to the SlyX family
HUF98_RS17130	COG0488	(ABC) transporter
HUF98_RS17135	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS17140	COG1560	Kdo2-lipid A biosynthetic process
HUF98_RS17150	COG1301	dicarboxylic acid transport
HUF98_RS17205	COG0473	3-isopropylmalate dehydrogenase activity
HUF98_RS17260	COG0583	DNA-binding transcription factor activity
HUF98_RS17270	COG0625	glutathione transferase activity
HUF98_RS17275	COG2378	regulation of single-species biofilm formation
HUF98_RS17280	COG0546	phosphoglycolate phosphatase activity
HUF98_RS17290	COG1530	ribonuclease E activity
HUF98_RS17295	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_RS17310	COG0583	DNA-binding transcription factor activity
HUF98_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS17320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUF98_RS17330	COG0534	Mate efflux family protein
HUF98_RS17345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUF98_RS17375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUF98_RS17375	COG0493	'glutamate synthase
HUF98_RS17385	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HUF98_RS17390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_RS17405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUF98_RS17415	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HUF98_RS17415	COG0644	oxidoreductase
HUF98_RS17425	COG0425	Belongs to the sulfur carrier protein TusA family
HUF98_RS17430	COG4535	Mg2 and Co2 transporter CorC
HUF98_RS17440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUF98_RS17460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUF98_RS17465	COG0475	glutathione-regulated potassium exporter activity
HUF98_RS17465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUF98_RS17480	COG0484	heat shock protein binding
HUF98_RS17485	COG0789	Transcriptional regulator
HUF98_RS17490	COG0598	Magnesium transport protein CorA
HUF98_RS17505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUF98_RS17510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUF98_RS17515	COG1074	ATP-dependent DNA helicase activity
HUF98_RS17520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HUF98_RS17540	COG2226	methyltransferase
HUF98_RS17560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUF98_RS17575	COG2111	Na H antiporter
HUF98_RS17575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUF98_RS17580	COG1006	Multisubunit Na H antiporter MnhC subunit
HUF98_RS17585	COG0651	ATP synthesis coupled electron transport
HUF98_RS17590	COG1863	multisubunit Na H antiporter MnhE subunit
HUF98_RS17595	COG2212	antiporter activity
HUF98_RS17600	COG1320	monovalent cation:proton antiporter activity
HUF98_RS17615	COG0195	Participates in both transcription termination and antitermination
HUF98_RS17665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HUF98_RS17670	COG0237	dephospho-CoA kinase activity
HUF98_RS17680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUF98_RS17695	COG0497	DNA recombination
HUF98_RS17705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUF98_RS17735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUF98_RS17735	COG2169	Transcriptional regulator
HUF98_RS17740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUF98_RS17805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUF98_RS17820	COG0326	Molecular chaperone. Has ATPase activity
HUF98_RS17835	COG2056	Na+-H+ antiporter family
HUF98_RS17840	COG0596	Alpha beta hydrolase
HUF98_RS17935	COG0546	phosphoglycolate phosphatase activity
HUF98_RS17940	COG1716	ATPase activity
HUF98_RS17985	COG0181	hydroxymethylbilane synthase activity
HUF98_RS17995	COG3275	phosphorelay sensor kinase activity
HUF98_RS18015	COG1538	Outer membrane efflux protein
HUF98_RS18020	COG0697	spore germination
HUF98_RS18045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUF98_RS18050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUF98_RS18055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUF98_RS18060	COG0772	Belongs to the SEDS family
HUF98_RS18085	COG4974	Belongs to the 'phage' integrase family
HUF98_RS18090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUF98_RS18100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUF98_RS18110	COG2197	response regulator
HUF98_RS18125	COG0793	Belongs to the peptidase S41A family
HUF98_RS18130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUF98_RS18135	COG0795	lipopolysaccharide-transporting ATPase activity
HUF98_RS18175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUF98_RS18175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUF98_RS18185	COG0004	ammonium transporteR
HUF98_RS18190	COG0347	Belongs to the P(II) protein family
HUF98_RS18200	COG0606	chelatase, subunit chli
HUF98_RS18205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_RS18215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_RS18235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUF98_RS18250	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_RS18260	COG0477	Major facilitator Superfamily
HUF98_RS18265	COG2860	membrane
HUF98_RS18275	COG1253	flavin adenine dinucleotide binding
HUF98_RS18285	COG0477	Major facilitator Superfamily
HUF98_RS18295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUF98_RS18335	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUF98_RS18345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUF98_RS18415	COG0758	DNA mediated transformation
HUF98_RS18425	COG0697	spore germination
HUF98_RS18430	COG1309	transcriptional regulator
HUF98_RS18445	COG0386	Belongs to the glutathione peroxidase family
HUF98_RS18510	COG1121	(ABC) transporter
HUF98_RS18515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUF98_RS18520	COG1280	lysine exporter protein (LysE YggA)
HUF98_RS18525	COG2837	iron assimilation
HUF98_RS18530	COG0281	malic enzyme
HUF98_RS18575	COG0519	Catalyzes the synthesis of GMP from XMP
HUF98_RS18575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUF98_RS18580	COG4399	Belongs to the UPF0754 family
HUF98_RS18585	COG2259	Doxx family
HUF98_RS18590	COG0586	Pfam SNARE associated Golgi protein
HUF98_RS18605	COG1192	Involved in chromosome partitioning
HUF98_RS18615	COG0271	Belongs to the BolA IbaG family
HUF98_RS18635	COG2267	carboxylic ester hydrolase activity
HUF98_RS18655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUF98_RS18655	COG3321	synthase
HUF98_RS18655	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUF98_RS18655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUF98_RS18660	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS18680	COG3916	Acyl-homoserine-lactone synthase
HUF98_RS18685	COG0477	Major facilitator Superfamily
HUF98_RS18690	COG1024	Enoyl-CoA hydratase
HUF98_RS18695	COG1024	Enoyl-CoA hydratase
HUF98_RS18700	COG1960	acyl-CoA dehydrogenase activity
HUF98_RS18705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUF98_RS18725	COG1113	amino acid transport
HUF98_RS18730	COG1113	amino acid transport
HUF98_RS18735	COG0251	oxidation-reduction process
HUF98_RS18775	COG0564	pseudouridine synthase activity
HUF98_RS18855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUF98_RS18870	COG1802	Transcriptional regulator
HUF98_RS18880	COG1448	Aminotransferase
HUF98_RS18885	COG0277	FAD linked oxidase domain protein
HUF98_RS18895	COG2186	Transcriptional regulator
HUF98_RS18905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUF98_RS18910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUF98_RS18925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUF98_RS18930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUF98_RS18935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUF98_RS18985	COG2244	polysaccharide biosynthetic process
HUF98_RS18990	COG1083	cytidylyl-transferase
HUF98_RS18995	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUF98_RS19005	COG2089	acid synthase
HUF98_RS19010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUF98_RS19015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUF98_RS19025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUF98_RS19030	COG1596	polysaccharide export
HUF98_RS19055	COG0728	peptidoglycan biosynthetic process
HUF98_RS19060	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUF98_RS19115	COG0546	phosphoglycolate phosphatase activity
HUF98_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_RS19140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUF98_RS19145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUF98_RS19150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUF98_RS19155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUF98_RS19160	COG1116	anion transmembrane transporter activity
HUF98_RS19165	COG1309	transcriptional regulator
HUF98_RS19170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUF98_RS19180	COG0196	riboflavin kinase activity
HUF98_RS19185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUF98_RS19195	COG1047	Peptidyl-prolyl cis-trans
HUF98_RS19235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUF98_RS19240	COG0657	acetylesterase activity
HUF98_RS19260	COG0583	DNA-binding transcription factor activity
HUF98_RS19290	COG2951	lytic endotransglycosylase activity
HUF98_RS19295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUF98_RS19310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUF98_RS19320	COG0671	phosphoesterase, PA-phosphatase related
HUF98_RS19325	COG0861	Integral membrane protein TerC family
HUF98_RS19335	COG0754	glutathionylspermidine amidase activity
HUF98_RS19345	COG0402	S-adenosylhomocysteine deaminase activity
HUF98_RS19360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUF98_RS19380	COG0706	membrane insertase activity
HUF98_RS19430	COG4683	PFAM Phage derived protein Gp49-like (DUF891)