locus-tag	class	description
AXA63_RS00010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AXA63_RS00075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXA63_RS00080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXA63_RS00080	COG2169	Transcriptional regulator
AXA63_RS00110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXA63_RS00120	COG0497	DNA recombination
AXA63_RS00135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXA63_RS00145	COG0237	dephospho-CoA kinase activity
AXA63_RS00195	COG0195	Participates in both transcription termination and antitermination
AXA63_RS00210	COG1320	monovalent cation:proton antiporter activity
AXA63_RS00215	COG2212	antiporter activity
AXA63_RS00220	COG1863	multisubunit Na H antiporter MnhE subunit
AXA63_RS00225	COG0651	ATP synthesis coupled electron transport
AXA63_RS00230	COG1006	Multisubunit Na H antiporter MnhC subunit
AXA63_RS00235	COG2111	Na H antiporter
AXA63_RS00235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXA63_RS00250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AXA63_RS00255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA63_RS00270	COG2226	methyltransferase
AXA63_RS00290	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AXA63_RS00295	COG1074	ATP-dependent DNA helicase activity
AXA63_RS00300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXA63_RS00305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXA63_RS00320	COG0598	Magnesium transport protein CorA
AXA63_RS00325	COG0789	Transcriptional regulator
AXA63_RS00330	COG0484	heat shock protein binding
AXA63_RS00340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AXA63_RS00345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXA63_RS00345	COG0475	glutathione-regulated potassium exporter activity
AXA63_RS00350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXA63_RS00370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA63_RS00380	COG4535	Mg2 and Co2 transporter CorC
AXA63_RS00385	COG0425	Belongs to the sulfur carrier protein TusA family
AXA63_RS00390	COG0644	oxidoreductase
AXA63_RS00390	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AXA63_RS00400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AXA63_RS00415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXA63_RS00420	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AXA63_RS00455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXA63_RS00475	COG0534	Mate efflux family protein
AXA63_RS00485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXA63_RS00490	COG4221	oxidoreductase activity
AXA63_RS00495	COG0583	DNA-binding transcription factor activity
AXA63_RS00510	COG0318	PFAM AMP-dependent synthetase and ligase
AXA63_RS00515	COG1530	ribonuclease E activity
AXA63_RS00525	COG0546	phosphoglycolate phosphatase activity
AXA63_RS00530	COG2378	regulation of single-species biofilm formation
AXA63_RS00535	COG0625	glutathione transferase activity
AXA63_RS00545	COG0583	DNA-binding transcription factor activity
AXA63_RS00610	COG0473	3-isopropylmalate dehydrogenase activity
AXA63_RS00665	COG1301	dicarboxylic acid transport
AXA63_RS00675	COG1560	Kdo2-lipid A biosynthetic process
AXA63_RS00680	COG1280	lysine exporter protein (LysE YggA)
AXA63_RS00685	COG0488	(ABC) transporter
AXA63_RS00690	COG2900	Belongs to the SlyX family
AXA63_RS00700	COG1733	regulation of RNA biosynthetic process
AXA63_RS00725	COG0210	DNA helicase
AXA63_RS00730	COG0724	RNA recognition motif
AXA63_RS00750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXA63_RS00750	COG4651	solute:proton antiporter activity
AXA63_RS00775	COG0788	formyltetrahydrofolate deformylase activity
AXA63_RS00875	COG2813	Specifically methylates the guanine in position
AXA63_RS00875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXA63_RS00885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXA63_RS00895	COG4774	siderophore transport
AXA63_RS00905	COG0740	serine-type endopeptidase activity
AXA63_RS00925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXA63_RS00925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXA63_RS00930	COG0857	belongs to the CobB CobQ family
AXA63_RS00930	COG0280	phosphate acetyltransferase
AXA63_RS00935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXA63_RS00945	COG0800	Aldolase
AXA63_RS00955	COG3265	gluconokinase activity
AXA63_RS00960	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS00970	COG2267	carboxylic ester hydrolase activity
AXA63_RS00985	COG0793	Belongs to the peptidase S41A family
AXA63_RS01020	COG1426	Protein conserved in bacteria
AXA63_RS01065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXA63_RS01075	COG0318	PFAM AMP-dependent synthetase and ligase
AXA63_RS01090	COG2986	histidine ammonia-lyase
AXA63_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS01135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXA63_RS01155	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXA63_RS01165	COG1162	GTPase activity
AXA63_RS01170	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AXA63_RS01185	COG1538	Outer membrane efflux protein
AXA63_RS01190	COG1136	(ABC) transporter
AXA63_RS01190	COG0577	efflux transmembrane transporter activity
AXA63_RS01195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA63_RS01220	COG0028	Belongs to the TPP enzyme family
AXA63_RS01225	COG0440	acetolactate synthase activity
AXA63_RS01255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXA63_RS01270	COG0084	hydrolase, TatD family'
AXA63_RS01285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXA63_RS01290	COG0583	DNA-binding transcription factor activity
AXA63_RS01300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXA63_RS01305	COG2814	Major facilitator Superfamily
AXA63_RS01315	COG0697	spore germination
AXA63_RS01345	COG3622	Belongs to the hyi family
AXA63_RS01350	COG2084	Dehydrogenase
AXA63_RS01355	COG1024	Enoyl-CoA hydratase
AXA63_RS01360	COG5002	protein histidine kinase activity
AXA63_RS01360	COG2205	protein histidine kinase activity
AXA63_RS01360	COG0784	Response regulator, receiver
AXA63_RS01380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXA63_RS01390	COG3956	TIGRFAM MazG family protein
AXA63_RS01395	COG1555	photosystem II stabilization
AXA63_RS01400	COG0617	tRNA 3'-terminal CCA addition
AXA63_RS01405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXA63_RS01425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA63_RS01430	COG3028	Belongs to the UPF0307 family
AXA63_RS01435	COG0318	PFAM AMP-dependent synthetase and ligase
AXA63_RS01450	COG0625	glutathione transferase activity
AXA63_RS01455	COG1238	metal cluster binding
AXA63_RS01495	COG0072	phenylalanine-tRNA ligase activity
AXA63_RS01520	COG0248	Ppx GppA phosphatase
AXA63_RS01530	COG0037	tRNA processing
AXA63_RS01570	COG1764	response to oxidative stress
AXA63_RS01575	COG1846	Transcriptional regulator
AXA63_RS01585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXA63_RS01645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXA63_RS01650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXA63_RS01655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXA63_RS01665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXA63_RS01715	COG1214	PFAM Peptidase M22, glycoprotease
AXA63_RS01740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXA63_RS01745	COG0561	phosphatase activity
AXA63_RS01755	COG2132	Multicopper oxidase
AXA63_RS01760	COG3667	copper resistance
AXA63_RS01775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXA63_RS01780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AXA63_RS01785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AXA63_RS01815	COG1063	alcohol dehydrogenase
AXA63_RS01820	COG0583	DNA-binding transcription factor activity
AXA63_RS01825	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS01830	COG2814	Major facilitator Superfamily
AXA63_RS01835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXA63_RS01845	COG1053	succinate dehydrogenase
AXA63_RS01850	COG0583	DNA-binding transcription factor activity
AXA63_RS01865	COG0583	DNA-binding transcription factor activity
AXA63_RS01905	COG3739	integral membrane protein
AXA63_RS01945	COG0583	DNA-binding transcription factor activity
AXA63_RS01960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXA63_RS01985	COG1061	Type III restriction enzyme res subunit
AXA63_RS01995	COG1192	Involved in chromosome partitioning
AXA63_RS02000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXA63_RS02010	COG1061	Type III restriction enzyme res subunit
AXA63_RS02035	COG1061	Type III restriction enzyme res subunit
AXA63_RS02045	COG1192	Involved in chromosome partitioning
AXA63_RS02050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXA63_RS02060	COG1061	Type III restriction enzyme res subunit
AXA63_RS02095	COG0384	phenazine biosynthesis protein PhzF
AXA63_RS02115	COG4993	Dehydrogenase
AXA63_RS02185	COG2205	protein histidine kinase activity
AXA63_RS02195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXA63_RS02215	COG0745	RESPONSE REGULATOR receiver
AXA63_RS02255	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXA63_RS02285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXA63_RS02290	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXA63_RS02310	COG0583	DNA-binding transcription factor activity
AXA63_RS02330	COG0668	transmembrane transport
AXA63_RS02340	COG2081	HI0933 family
AXA63_RS02345	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AXA63_RS02375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA63_RS02375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXA63_RS02385	COG0489	protein tyrosine kinase activity
AXA63_RS02435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXA63_RS02445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXA63_RS02460	COG0730	response to heat
AXA63_RS02470	COG1196	nuclear chromosome segregation
AXA63_RS02490	COG2223	nitrite transmembrane transporter activity
AXA63_RS02495	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AXA63_RS02500	COG1877	trehalose-phosphatase activity
AXA63_RS02505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXA63_RS02505	COG2226	methyltransferase
AXA63_RS02505	COG0596	Alpha beta hydrolase
AXA63_RS02520	COG4106	trans-aconitate 2-methyltransferase activity
AXA63_RS02535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXA63_RS02540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AXA63_RS02545	COG0009	L-threonylcarbamoyladenylate synthase
AXA63_RS02550	COG3101	peptidyl-lysine hydroxylation
AXA63_RS02555	COG1399	metal-binding, possibly nucleic acid-binding protein
AXA63_RS02580	COG1652	LysM domain
AXA63_RS02585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXA63_RS02585	COG0352	thiamine-phosphate diphosphorylase activity
AXA63_RS02585	COG0351	phosphomethylpyrimidine kinase
AXA63_RS02595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXA63_RS02625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXA63_RS02655	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AXA63_RS02670	COG0358	DNA primase activity
AXA63_RS02680	COG0564	pseudouridine synthase activity
AXA63_RS02705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXA63_RS02725	COG0583	DNA-binding transcription factor activity
AXA63_RS02730	COG0473	3-isopropylmalate dehydrogenase activity
AXA63_RS02740	COG0657	acetylesterase activity
AXA63_RS02750	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS02770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AXA63_RS02770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXA63_RS02785	COG1981	membrane
AXA63_RS02830	COG0456	acetyltransferase
AXA63_RS02840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXA63_RS02845	COG0492	ferredoxin-NADP+ reductase activity
AXA63_RS02850	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXA63_RS02850	COG1674	ftsk spoiiie
AXA63_RS02855	COG1280	lysine exporter protein (LysE YggA)
AXA63_RS02880	COG2894	cell division
AXA63_RS02895	COG0204	Acyl-transferase
AXA63_RS02900	COG2885	chlorophyll binding
AXA63_RS02905	COG0210	DNA helicase
AXA63_RS02915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXA63_RS02930	COG0121	glutamine amidotransferase
AXA63_RS02950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXA63_RS02955	COG0735	belongs to the Fur family
AXA63_RS02980	COG0420	3'-5' exonuclease activity
AXA63_RS03000	COG1090	epimerase
AXA63_RS03015	COG2050	protein possibly involved in aromatic compounds catabolism
AXA63_RS03025	COG2814	Major facilitator Superfamily
AXA63_RS03030	COG0405	Gamma-glutamyltransferase
AXA63_RS03055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXA63_RS03165	COG1484	DNA-dependent DNA replication
AXA63_RS03210	COG3755	Protein conserved in bacteria
AXA63_RS03355	COG2026	Addiction module toxin, RelE StbE family
AXA63_RS03395	COG0592	DNA-directed DNA polymerase activity
AXA63_RS03475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXA63_RS03530	COG0477	Major facilitator Superfamily
AXA63_RS03535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXA63_RS03545	COG1595	DNA-templated transcription, initiation
AXA63_RS03600	COG0531	amino acid
AXA63_RS03605	COG2040	homocysteine
AXA63_RS03630	COG1309	transcriptional regulator
AXA63_RS03635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXA63_RS03640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXA63_RS03650	COG1607	acyl-coa hydrolase
AXA63_RS03660	COG0523	cobalamin synthesis protein
AXA63_RS03670	COG4681	YaeQ
AXA63_RS03680	COG0726	polysaccharide deacetylase
AXA63_RS03680	COG1649	PFAM Uncharacterised BCR, COG1649
AXA63_RS03685	COG1215	transferase activity, transferring glycosyl groups
AXA63_RS03695	COG1024	Enoyl-CoA hydratase
AXA63_RS03710	COG1414	Transcriptional regulator
AXA63_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS03740	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA63_RS03745	COG2271	Major facilitator Superfamily
AXA63_RS03755	COG2267	carboxylic ester hydrolase activity
AXA63_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS03775	COG0028	Belongs to the TPP enzyme family
AXA63_RS03785	COG0477	Major facilitator Superfamily
AXA63_RS03790	COG0242	peptide deformylase activity
AXA63_RS03795	COG2066	Belongs to the glutaminase family
AXA63_RS03800	COG2207	Transcriptional regulator
AXA63_RS03805	COG2223	nitrite transmembrane transporter activity
AXA63_RS03820	COG0583	DNA-binding transcription factor activity
AXA63_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS03830	COG2271	Major facilitator Superfamily
AXA63_RS03835	COG3959	Transketolase, thiamine diphosphate binding domain
AXA63_RS03840	COG3958	Transketolase
AXA63_RS03850	COG0306	phosphate transporter
AXA63_RS03870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXA63_RS03915	COG4181	ATPase activity
AXA63_RS03920	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AXA63_RS03945	COG0583	DNA-binding transcription factor activity
AXA63_RS03955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXA63_RS03960	COG1773	rubredoxin
AXA63_RS04005	COG2851	Citrate transporter
AXA63_RS04015	COG1253	flavin adenine dinucleotide binding
AXA63_RS04065	COG0830	nickel cation binding
AXA63_RS04080	COG0742	ribosomal rna small subunit methyltransferase
AXA63_RS04085	COG0768	penicillin binding
AXA63_RS04105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXA63_RS04110	COG2878	Part of a membrane complex involved in electron transport
AXA63_RS04115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXA63_RS04125	COG3384	dioxygenase
AXA63_RS04150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXA63_RS04475	COG0739	heme binding
AXA63_RS04520	COG2194	sulfuric ester hydrolase activity
AXA63_RS04555	COG0006	proline dipeptidase activity
AXA63_RS04560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA63_RS04565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA63_RS04585	COG1279	arginine transmembrane transporter activity
AXA63_RS04590	COG0583	DNA-binding transcription factor activity
AXA63_RS04630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXA63_RS04635	COG1388	LysM domain
AXA63_RS04635	COG0741	lytic transglycosylase activity
AXA63_RS04635	COG0741	lytic transglycosylase activity
AXA63_RS04635	COG1388	LysM domain
AXA63_RS04645	COG4174	ABC transporter (Permease)
AXA63_RS04650	COG4239	(ABC) transporter, permease
AXA63_RS04655	COG4172	Belongs to the ABC transporter superfamily
AXA63_RS04675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXA63_RS04685	COG3706	GGDEF domain
AXA63_RS04685	COG4251	negative regulation of phosphorylation
AXA63_RS04685	COG2203	Gaf domain
AXA63_RS04685	COG5001	Diguanylate cyclase
AXA63_RS04695	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA63_RS04695	COG1902	pentaerythritol trinitrate reductase activity
AXA63_RS04710	COG4269	membrane
AXA63_RS04735	COG3209	COG3209 Rhs family protein
AXA63_RS04780	COG1113	amino acid transport
AXA63_RS04790	COG0531	amino acid
AXA63_RS04810	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS04830	COG1113	amino acid transport
AXA63_RS04855	COG2072	flavoprotein involved in K transport
AXA63_RS04860	COG0300	oxidoreductase activity
AXA63_RS04870	COG1309	transcriptional regulator
AXA63_RS04875	COG1741	Belongs to the pirin family
AXA63_RS04890	COG2072	flavoprotein involved in K transport
AXA63_RS04900	COG2252	PERMEase
AXA63_RS04905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AXA63_RS04910	COG3038	cytochrome b561
AXA63_RS04920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXA63_RS04930	COG0527	aspartate kinase activity
AXA63_RS04940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXA63_RS04950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXA63_RS04965	COG0667	Aldo Keto reductase
AXA63_RS04985	COG1765	OsmC-like protein
AXA63_RS05000	COG0542	response to heat
AXA63_RS05035	COG2885	chlorophyll binding
AXA63_RS05045	COG0625	glutathione transferase activity
AXA63_RS05050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXA63_RS05070	COG3634	alkyl hydroperoxide reductase activity
AXA63_RS05080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXA63_RS05090	COG0450	alkyl hydroperoxide reductase
AXA63_RS05095	COG1643	Atp-dependent helicase
AXA63_RS05110	COG2814	Major facilitator Superfamily
AXA63_RS05115	COG3135	benzoate transporter
AXA63_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS05125	COG0543	2 iron, 2 sulfur cluster binding
AXA63_RS05125	COG0633	Ferredoxin
AXA63_RS05130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXA63_RS05135	COG4638	Rieske (2fe-2S)
AXA63_RS05140	COG0583	DNA-binding transcription factor activity
AXA63_RS05190	COG1570	exodeoxyribonuclease VII activity
AXA63_RS05225	COG1280	lysine exporter protein (LysE YggA)
AXA63_RS05230	COG1278	Cold shock
AXA63_RS05260	COG2814	Major facilitator Superfamily
AXA63_RS05300	COG0517	IMP dehydrogenase activity
AXA63_RS05300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AXA63_RS05305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXA63_RS05315	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AXA63_RS05320	COG1137	ATPase activity
AXA63_RS05325	COG1538	Outer membrane efflux protein
AXA63_RS05355	COG4122	O-methyltransferase activity
AXA63_RS05365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXA63_RS05380	COG1522	sequence-specific DNA binding
AXA63_RS05385	COG5006	permease, DMT superfamily
AXA63_RS05395	COG1560	Kdo2-lipid A biosynthetic process
AXA63_RS05405	COG2814	Major facilitator Superfamily
AXA63_RS05425	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXA63_RS05470	COG0583	DNA-binding transcription factor activity
AXA63_RS05475	COG1914	H( )-stimulated, divalent metal cation uptake system
AXA63_RS05495	COG4770	biotin carboxylase activity
AXA63_RS05500	COG0038	chloride channel
AXA63_RS05525	COG1309	transcriptional regulator
AXA63_RS05535	COG1063	alcohol dehydrogenase
AXA63_RS05550	COG0439	Biotin carboxylase
AXA63_RS05555	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXA63_RS05560	COG1733	regulation of RNA biosynthetic process
AXA63_RS05575	COG0864	Transcriptional regulator
AXA63_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA63_RS05590	COG1116	anion transmembrane transporter activity
AXA63_RS05615	COG0789	Transcriptional regulator
AXA63_RS05625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXA63_RS05645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA63_RS05655	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA63_RS05670	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS05675	COG0531	amino acid
AXA63_RS05680	COG1760	l-serine dehydratase
AXA63_RS05685	COG2030	dehydratase
AXA63_RS05685	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS05690	COG3396	Phenylacetate-CoA oxygenase
AXA63_RS05695	COG3460	Phenylacetate-CoA oxygenase
AXA63_RS05700	COG3396	Phenylacetate-CoA oxygenase
AXA63_RS05705	COG2151	metal-sulfur cluster biosynthetic enzyme
AXA63_RS05710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXA63_RS05715	COG1024	Enoyl-CoA hydratase
AXA63_RS05720	COG1024	Enoyl-CoA hydratase
AXA63_RS05725	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXA63_RS05730	COG0183	Belongs to the thiolase family
AXA63_RS05735	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AXA63_RS05740	COG3327	negative regulation of DNA-templated transcription, initiation
AXA63_RS05750	COG2050	protein possibly involved in aromatic compounds catabolism
AXA63_RS05785	COG0753	catalase activity
AXA63_RS05790	COG3038	cytochrome b561
AXA63_RS05810	COG2267	carboxylic ester hydrolase activity
AXA63_RS05815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXA63_RS05820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXA63_RS05825	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS05830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXA63_RS05840	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS05845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXA63_RS05850	COG0583	DNA-binding transcription factor activity
AXA63_RS05860	COG1414	Transcriptional regulator
AXA63_RS05865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA63_RS05875	COG1840	ABC-type Fe3 transport system, periplasmic component
AXA63_RS05880	COG3842	ATPase activity
AXA63_RS05895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXA63_RS05900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXA63_RS05905	COG2814	Major facilitator Superfamily
AXA63_RS05910	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS05925	COG1024	Enoyl-CoA hydratase
AXA63_RS05935	COG2814	Major facilitator Superfamily
AXA63_RS05945	COG0183	Belongs to the thiolase family
AXA63_RS05950	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXA63_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS05960	COG1024	Enoyl-CoA hydratase
AXA63_RS05965	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS05970	COG2814	Major facilitator Superfamily
AXA63_RS05975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXA63_RS05980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXA63_RS05990	COG2814	Major facilitator Superfamily
AXA63_RS06000	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS06015	COG0583	DNA-binding transcription factor activity
AXA63_RS06025	COG4770	biotin carboxylase activity
AXA63_RS06030	COG1024	Enoyl-CoA hydratase
AXA63_RS06035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXA63_RS06040	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS06045	COG1309	transcriptional regulator
AXA63_RS06050	COG0318	PFAM AMP-dependent synthetase and ligase
AXA63_RS06070	COG0583	DNA-binding transcription factor activity
AXA63_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS06140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXA63_RS06160	COG0784	Response regulator, receiver
AXA63_RS06160	COG2205	protein histidine kinase activity
AXA63_RS06175	COG0765	amino acid transport
AXA63_RS06180	COG0765	amino acid transport
AXA63_RS06185	COG1126	abc transporter atp-binding protein
AXA63_RS06190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA63_RS06195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXA63_RS06205	COG1280	lysine exporter protein (LysE YggA)
AXA63_RS06210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXA63_RS06215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXA63_RS06220	COG1045	serine acetyltransferase
AXA63_RS06235	COG0583	DNA-binding transcription factor activity
AXA63_RS06240	COG0625	glutathione transferase activity
AXA63_RS06245	COG0625	glutathione transferase activity
AXA63_RS06250	COG0583	DNA-binding transcription factor activity
AXA63_RS06260	COG1346	cytolysis
AXA63_RS06280	COG2814	Major facilitator Superfamily
AXA63_RS06290	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AXA63_RS06295	COG3052	prosthetic group binding
AXA63_RS06315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXA63_RS06335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXA63_RS06345	COG1294	oxidase, subunit
AXA63_RS06350	COG1271	oxidase subunit
AXA63_RS06370	COG0477	Major facilitator Superfamily
AXA63_RS06380	COG4521	taurine ABC transporter
AXA63_RS06385	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXA63_RS06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXA63_RS06395	COG2175	clavaminate synthase activity
AXA63_RS06405	COG1953	Uracil, thiamine, allantoin
AXA63_RS06415	COG0583	DNA-binding transcription factor activity
AXA63_RS06425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXA63_RS06440	COG0640	Transcriptional regulator
AXA63_RS06445	COG0798	PFAM Bile acid sodium symporter
AXA63_RS06450	COG0583	DNA-binding transcription factor activity
AXA63_RS06465	COG3634	alkyl hydroperoxide reductase activity
AXA63_RS06505	COG0436	Aminotransferase
AXA63_RS06515	COG0386	Belongs to the glutathione peroxidase family
AXA63_RS06555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXA63_RS06580	COG0012	GTP binding
AXA63_RS06585	COG2011	ABC-type metal ion transport system permease component
AXA63_RS06590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXA63_RS06600	COG1464	Belongs to the NlpA lipoprotein family
AXA63_RS06630	COG0765	amino acid transport
AXA63_RS06635	COG0765	amino acid transport
AXA63_RS06640	COG1126	abc transporter atp-binding protein
AXA63_RS06650	COG1522	sequence-specific DNA binding
AXA63_RS06675	COG1309	transcriptional regulator
AXA63_RS06705	COG0583	DNA-binding transcription factor activity
AXA63_RS06715	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXA63_RS06725	COG0697	spore germination
AXA63_RS06750	COG3121	Chaperone
AXA63_RS06755	COG3539	Fimbrial protein
AXA63_RS06780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXA63_RS06780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXA63_RS06825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXA63_RS06835	COG2353	YceI-like domain
AXA63_RS06845	COG3698	Phosphodiester glycosidase
AXA63_RS06860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXA63_RS06865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXA63_RS06865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXA63_RS06865	COG0506	proline dehydrogenase activity
AXA63_RS06875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXA63_RS06880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXA63_RS06900	COG1132	(ABC) transporter
AXA63_RS06905	COG3122	Protein conserved in bacteria
AXA63_RS06910	COG3619	membrane
AXA63_RS06920	COG0640	Transcriptional regulator
AXA63_RS06930	COG2850	peptidyl-arginine hydroxylation
AXA63_RS06935	COG0424	maF-like protein
AXA63_RS06955	COG0191	fructose-bisphosphate aldolase activity
AXA63_RS06960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXA63_RS06975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXA63_RS06985	COG1192	Involved in chromosome partitioning
AXA63_RS06990	COG1475	DNA binding
AXA63_RS06995	COG0811	peptide transport
AXA63_RS07005	COG1132	(ABC) transporter
AXA63_RS07010	COG1663	tetraacyldisaccharide 4'-kinase activity
AXA63_RS07030	COG0084	hydrolase, TatD family'
AXA63_RS07095	COG0776	regulation of translation
AXA63_RS07125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXA63_RS07130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXA63_RS07175	COG0339	signal peptide processing
AXA63_RS07185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXA63_RS07220	COG0702	epimerase
AXA63_RS07225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXA63_RS07245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXA63_RS07275	COG0316	Belongs to the HesB IscA family
AXA63_RS07280	COG0822	iron-sulfur transferase activity
AXA63_RS07305	COG0776	regulation of translation
AXA63_RS07310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXA63_RS07315	COG2207	Transcriptional regulator
AXA63_RS07320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA63_RS07325	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS07330	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS07345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXA63_RS07365	COG4264	IucA IucC family
AXA63_RS07370	COG4264	IucA IucC family
AXA63_RS07410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXA63_RS07425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AXA63_RS07445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXA63_RS07450	COG0730	response to heat
AXA63_RS07470	COG4773	Receptor
AXA63_RS07475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA63_RS07490	COG1131	(ABC) transporter
AXA63_RS07495	COG0842	Transport permease protein
AXA63_RS07500	COG0842	Transport permease protein
AXA63_RS07555	COG2226	methyltransferase
AXA63_RS07590	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXA63_RS07625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXA63_RS07635	COG0133	tryptophan synthase activity
AXA63_RS07650	COG3706	GGDEF domain
AXA63_RS07665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXA63_RS07670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXA63_RS07675	COG0022	dehydrogenase e1 component
AXA63_RS07680	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXA63_RS07685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXA63_RS07695	COG1063	alcohol dehydrogenase
AXA63_RS07700	COG3781	membrane
AXA63_RS07710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXA63_RS07710	COG3453	Protein conserved in bacteria
AXA63_RS07720	COG0730	response to heat
AXA63_RS07735	COG2207	Transcriptional regulator
AXA63_RS07735	COG3708	Transcriptional regulator
AXA63_RS07740	COG1733	regulation of RNA biosynthetic process
AXA63_RS07745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXA63_RS07755	COG2188	Transcriptional regulator
AXA63_RS07770	COG4521	taurine ABC transporter
AXA63_RS07775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXA63_RS07795	COG0477	Major facilitator Superfamily
AXA63_RS07805	COG1027	Aspartate ammonia-lyase
AXA63_RS07820	COG0583	DNA-binding transcription factor activity
AXA63_RS07825	COG0583	DNA-binding transcription factor activity
AXA63_RS07830	COG0183	Belongs to the thiolase family
AXA63_RS07835	COG2031	fatty acid transporter
AXA63_RS07840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXA63_RS07850	COG0583	DNA-binding transcription factor activity
AXA63_RS07860	COG2610	gluconate transmembrane transporter activity
AXA63_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS07880	COG2207	Transcriptional regulator
AXA63_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS07920	COG0543	2 iron, 2 sulfur cluster binding
AXA63_RS07920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXA63_RS07925	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXA63_RS07930	COG4638	Rieske (2fe-2S)
AXA63_RS07940	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXA63_RS07945	COG4149	molybdate abc transporter
AXA63_RS07950	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXA63_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS07960	COG1535	isochorismatase
AXA63_RS07960	COG3433	isochorismatase activity
AXA63_RS08020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXA63_RS08035	COG0753	catalase activity
AXA63_RS08045	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AXA63_RS08080	COG3539	Fimbrial protein
AXA63_RS08105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA63_RS08125	COG2072	flavoprotein involved in K transport
AXA63_RS08135	COG1538	Outer membrane efflux protein
AXA63_RS08140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXA63_RS08145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA63_RS08150	COG0745	RESPONSE REGULATOR receiver
AXA63_RS08155	COG2205	protein histidine kinase activity
AXA63_RS08165	COG2207	Transcriptional regulator
AXA63_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS08235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AXA63_RS08355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXA63_RS08375	COG1120	ATPase activity
AXA63_RS08380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA63_RS08390	COG1064	alcohol dehydrogenase
AXA63_RS08405	COG2207	Transcriptional regulator
AXA63_RS08410	COG2084	Dehydrogenase
AXA63_RS08420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXA63_RS08425	COG0583	DNA-binding transcription factor activity
AXA63_RS08435	COG0129	dihydroxy-acid dehydratase activity
AXA63_RS08440	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS08455	COG1566	PFAM secretion protein HlyD family protein
AXA63_RS08475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXA63_RS08505	COG0583	DNA-binding transcription factor activity
AXA63_RS08520	COG2188	Transcriptional regulator
AXA63_RS08550	COG3210	domain, Protein
AXA63_RS08555	COG2831	hemolysin activation secretion protein
AXA63_RS08575	COG1473	amidohydrolase
AXA63_RS08585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXA63_RS08585	COG0475	glutathione-regulated potassium exporter activity
AXA63_RS08595	COG0583	DNA-binding transcription factor activity
AXA63_RS08600	COG1335	isochorismatase
AXA63_RS08610	COG1309	transcriptional regulator
AXA63_RS08640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AXA63_RS08650	COG1902	pentaerythritol trinitrate reductase activity
AXA63_RS08650	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA63_RS08655	COG1846	Transcriptional regulator
AXA63_RS08690	COG0753	catalase activity
AXA63_RS08705	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS08720	COG3162	membrane
AXA63_RS08730	COG3829	transcription factor binding
AXA63_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS08740	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS08780	COG2186	Transcriptional regulator
AXA63_RS08790	COG0583	DNA-binding transcription factor activity
AXA63_RS08795	COG4948	Mandelate Racemase Muconate Lactonizing
AXA63_RS08800	COG4829	muconolactone delta-isomerase
AXA63_RS08810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXA63_RS08815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXA63_RS08820	COG0183	Belongs to the thiolase family
AXA63_RS08825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXA63_RS08835	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS08845	COG3733	amine oxidase
AXA63_RS08855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXA63_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS08875	COG4638	Rieske (2fe-2S)
AXA63_RS08895	COG0154	amidase activity
AXA63_RS08905	COG2814	Major facilitator Superfamily
AXA63_RS08930	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS08935	COG0583	DNA-binding transcription factor activity
AXA63_RS08940	COG1414	Transcriptional regulator
AXA63_RS08955	COG2391	methyltransferase activity
AXA63_RS08965	COG4993	Dehydrogenase
AXA63_RS08970	COG3659	wide pore channel activity
AXA63_RS08975	COG3420	alginic acid biosynthetic process
AXA63_RS08980	COG0710	3-dehydroquinate dehydratase activity
AXA63_RS08985	COG3485	protocatechuate 3,4-dioxygenase
AXA63_RS08990	COG3485	protocatechuate 3,4-dioxygenase
AXA63_RS08995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXA63_RS09000	COG2271	Major facilitator Superfamily
AXA63_RS09005	COG0596	Alpha beta hydrolase
AXA63_RS09010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXA63_RS09015	COG0183	Belongs to the thiolase family
AXA63_RS09020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXA63_RS09025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXA63_RS09035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AXA63_RS09040	COG2323	membrane
AXA63_RS09085	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXA63_RS09085	COG1902	pentaerythritol trinitrate reductase activity
AXA63_RS09110	COG0542	response to heat
AXA63_RS09115	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXA63_RS09145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXA63_RS09150	COG0569	domain protein
AXA63_RS09155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXA63_RS09170	COG4774	siderophore transport
AXA63_RS09175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXA63_RS09185	COG1585	Membrane protein implicated in regulation of membrane protease activity
AXA63_RS09210	COG1294	oxidase, subunit
AXA63_RS09215	COG4890	Cyd operon protein YbgT
AXA63_RS09230	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AXA63_RS09240	COG0552	protein localization to endoplasmic reticulum
AXA63_RS09265	COG0516	GMP reductase activity
AXA63_RS09265	COG0517	IMP dehydrogenase activity
AXA63_RS09270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXA63_RS09275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXA63_RS09285	COG0583	DNA-binding transcription factor activity
AXA63_RS09290	COG0024	Methionine aminopeptidase
AXA63_RS09320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXA63_RS09320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXA63_RS09325	COG1105	Belongs to the carbohydrate kinase PfkB family
AXA63_RS09330	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AXA63_RS09330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA63_RS09330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXA63_RS09350	COG3300	MHYT domain
AXA63_RS09350	COG5001	Diguanylate cyclase
AXA63_RS09375	COG2135	peptidase activity
AXA63_RS09380	COG0659	secondary active sulfate transmembrane transporter activity
AXA63_RS09395	COG1113	amino acid transport
AXA63_RS09405	COG1522	sequence-specific DNA binding
AXA63_RS09430	COG1011	Hydrolase
AXA63_RS09435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXA63_RS09445	COG2137	regulation of response to DNA damage stimulus
AXA63_RS09460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA63_RS09495	COG0575	Belongs to the CDS family
AXA63_RS09500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXA63_RS09520	COG3852	Histidine kinase
AXA63_RS09525	COG2204	response regulator
AXA63_RS09580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXA63_RS09585	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AXA63_RS09605	COG0697	spore germination
AXA63_RS09610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXA63_RS09620	COG0303	'Molybdopterin
AXA63_RS09625	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXA63_RS09625	COG0315	cyclic pyranopterin monophosphate synthase activity
AXA63_RS09640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXA63_RS09645	COG0243	molybdopterin cofactor binding
AXA63_RS09655	COG0243	molybdopterin cofactor binding
AXA63_RS09660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXA63_RS09665	COG2146	nitrite reductase [NAD(P)H] activity
AXA63_RS09665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXA63_RS09675	COG0745	RESPONSE REGULATOR receiver
AXA63_RS09680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXA63_RS09680	COG1116	anion transmembrane transporter activity
AXA63_RS09695	COG0511	ligase activity, forming carbon-carbon bonds
AXA63_RS09710	COG2814	Major facilitator Superfamily
AXA63_RS09780	COG0739	heme binding
AXA63_RS09900	COG5410	chromosome segregation
AXA63_RS10060	COG0069	glutamate synthase activity
AXA63_RS10080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXA63_RS10090	COG1454	alcohol dehydrogenase
AXA63_RS10095	COG0824	Thioesterase
AXA63_RS10105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXA63_RS10120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXA63_RS10125	COG2030	dehydratase
AXA63_RS10135	COG0183	Belongs to the thiolase family
AXA63_RS10145	COG0583	DNA-binding transcription factor activity
AXA63_RS10150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXA63_RS10160	COG1522	sequence-specific DNA binding
AXA63_RS10165	COG3135	benzoate transporter
AXA63_RS10175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXA63_RS10195	COG0589	response to stress
AXA63_RS10200	COG0488	(ABC) transporter
AXA63_RS10220	COG4773	Receptor
AXA63_RS10260	COG0668	transmembrane transport
AXA63_RS10270	COG1309	transcriptional regulator
AXA63_RS10285	COG1605	Chorismate mutase
AXA63_RS10295	COG4221	oxidoreductase activity
AXA63_RS10305	COG0308	aminopeptidase N
AXA63_RS10325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AXA63_RS10335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXA63_RS10340	COG1454	alcohol dehydrogenase
AXA63_RS10360	COG0531	amino acid
AXA63_RS10365	COG4303	Ethanolamine ammonia lyase large subunit
AXA63_RS10370	COG4302	ethanolamine ammonia-lyase activity
AXA63_RS10375	COG0519	Catalyzes the synthesis of GMP from XMP
AXA63_RS10375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXA63_RS10380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXA63_RS10390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXA63_RS10405	COG0697	spore germination
AXA63_RS10410	COG1923	regulation of RNA biosynthetic process
AXA63_RS10420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXA63_RS10425	COG0802	atpase or kinase
AXA63_RS10445	COG1187	pseudouridine synthase activity
AXA63_RS10460	COG0583	DNA-binding transcription factor activity
AXA63_RS10520	COG3267	Type II secretory pathway component ExeA
AXA63_RS10520	COG3409	Peptidoglycan-binding domain 1 protein
AXA63_RS10545	COG0681	Belongs to the peptidase S26 family
AXA63_RS10580	COG4373	Mu-like prophage FluMu protein gp28
AXA63_RS10595	COG4383	Mu-like prophage protein gp29
AXA63_RS10600	COG2369	cell adhesion
AXA63_RS10605	COG5005	Phage virion morphogenesis
AXA63_RS10620	COG4397	Mu-like prophage major head subunit gpT
AXA63_RS10715	COG2814	Major facilitator Superfamily
AXA63_RS10720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXA63_RS10745	COG0729	surface antigen
AXA63_RS10765	COG0174	glutamine synthetase
AXA63_RS10770	COG0745	RESPONSE REGULATOR receiver
AXA63_RS10775	COG2205	protein histidine kinase activity
AXA63_RS10785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AXA63_RS10790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AXA63_RS10815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXA63_RS10820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXA63_RS10825	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS10840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXA63_RS10845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXA63_RS10865	COG0583	DNA-binding transcription factor activity
AXA63_RS10880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXA63_RS10895	COG1215	transferase activity, transferring glycosyl groups
AXA63_RS10900	COG1649	PFAM Uncharacterised BCR, COG1649
AXA63_RS10900	COG0726	polysaccharide deacetylase
AXA63_RS10925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXA63_RS10930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXA63_RS10940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXA63_RS10965	COG0305	Participates in initiation and elongation during chromosome replication
AXA63_RS10970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXA63_RS10980	COG1305	Transglutaminase-like
AXA63_RS10990	COG2308	Evidence 4 Homologs of previously reported genes of
AXA63_RS11020	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AXA63_RS11025	COG0138	bifunctional purine biosynthesis protein purh
AXA63_RS11030	COG0151	Belongs to the GarS family
AXA63_RS11035	COG1464	Belongs to the NlpA lipoprotein family
AXA63_RS11040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXA63_RS11045	COG2011	ABC-type metal ion transport system permease component
AXA63_RS11050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXA63_RS11060	COG1301	dicarboxylic acid transport
AXA63_RS11070	COG3173	Aminoglycoside phosphotransferase
AXA63_RS11075	COG0488	(ABC) transporter
AXA63_RS11140	COG3173	Aminoglycoside phosphotransferase
AXA63_RS11145	COG0488	(ABC) transporter
AXA63_RS11225	COG1794	racemase activity, acting on amino acids and derivatives
AXA63_RS11235	COG3008	intermembrane lipid transfer
AXA63_RS11235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXA63_RS11240	COG2995	paraquat-inducible protein a
AXA63_RS11250	COG2985	domain, Protein
AXA63_RS11275	COG0477	Major facilitator Superfamily
AXA63_RS11340	COG2186	Transcriptional regulator
AXA63_RS11350	COG0786	glutamate:sodium symporter activity
AXA63_RS11355	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXA63_RS11380	COG3111	PFAM Bacterial OB fold (BOF) protein
AXA63_RS11480	COG1610	YqeY-like protein
AXA63_RS11485	COG4783	chaperone-mediated protein folding
AXA63_RS11510	COG1286	toxin biosynthetic process
AXA63_RS11540	COG0778	Nitroreductase
AXA63_RS11550	COG0513	Belongs to the DEAD box helicase family
AXA63_RS11570	COG2363	Small membrane protein
AXA63_RS11600	COG1234	tRNA 3'-trailer cleavage
AXA63_RS11605	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXA63_RS11615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXA63_RS11625	COG2819	hydrolase of the alpha beta superfamily
AXA63_RS11630	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS11635	COG1301	dicarboxylic acid transport
AXA63_RS11640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXA63_RS11645	COG3139	Protein of unknown function (DUF1315)
AXA63_RS11650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AXA63_RS11655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXA63_RS11665	COG0494	nUDIX hydrolase
AXA63_RS11675	COG0642	Histidine kinase
AXA63_RS11690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXA63_RS11700	COG1720	tRNA m6t6A37 methyltransferase activity
AXA63_RS11715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXA63_RS11720	COG0826	peptidase U32
AXA63_RS11725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXA63_RS11735	COG4598	ABC transporter
AXA63_RS11740	COG4160	amino acid transport
AXA63_RS11745	COG4215	(ABC) transporter
AXA63_RS11760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA63_RS11805	COG1131	(ABC) transporter
AXA63_RS11810	COG0842	Transport permease protein
AXA63_RS11825	COG0772	Belongs to the SEDS family
AXA63_RS11830	COG2951	lytic endotransglycosylase activity
AXA63_RS11855	COG2207	Transcriptional regulator
AXA63_RS11870	COG0052	Belongs to the universal ribosomal protein uS2 family
AXA63_RS11875	COG0024	Methionine aminopeptidase
AXA63_RS11885	COG2223	nitrite transmembrane transporter activity
AXA63_RS11900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXA63_RS11905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXA63_RS11910	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS11925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXA63_RS11930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AXA63_RS11935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXA63_RS11955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXA63_RS11960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXA63_RS11965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXA63_RS12000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AXA63_RS12010	COG0174	glutamine synthetase
AXA63_RS12025	COG0582	viral genome integration into host DNA
AXA63_RS12315	COG3620	sequence-specific DNA binding
AXA63_RS12380	COG0512	Glutamine amidotransferase of anthranilate synthase
AXA63_RS12385	COG0308	aminopeptidase N
AXA63_RS12415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXA63_RS12425	COG0302	gtp cyclohydrolase
AXA63_RS12455	COG3739	integral membrane protein
AXA63_RS12480	COG1169	isochorismate synthase
AXA63_RS12490	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AXA63_RS12495	COG1132	(ABC) transporter
AXA63_RS12500	COG1132	(ABC) transporter
AXA63_RS12515	COG3433	isochorismatase activity
AXA63_RS12515	COG1535	isochorismatase
AXA63_RS12520	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXA63_RS12525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA63_RS12535	COG4774	siderophore transport
AXA63_RS12540	COG4607	ABC-type enterochelin transport system periplasmic component
AXA63_RS12545	COG4604	ABC transporter, ATP-binding protein
AXA63_RS12550	COG4605	iron ion homeostasis
AXA63_RS12555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXA63_RS12560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA63_RS12575	COG2964	Protein conserved in bacteria
AXA63_RS12585	COG1741	Belongs to the pirin family
AXA63_RS12600	COG1309	transcriptional regulator
AXA63_RS12610	COG4948	Mandelate Racemase Muconate Lactonizing
AXA63_RS12615	COG2814	Major facilitator Superfamily
AXA63_RS12650	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AXA63_RS12650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXA63_RS12655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXA63_RS12660	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS12670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXA63_RS12675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXA63_RS12685	COG0583	DNA-binding transcription factor activity
AXA63_RS12690	COG1113	amino acid transport
AXA63_RS12710	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AXA63_RS12710	COG2508	Transcriptional regulator
AXA63_RS12740	COG2879	small protein
AXA63_RS12745	COG1966	Carbon starvation protein
AXA63_RS12790	COG1067	ATP-dependent peptidase activity
AXA63_RS12795	COG0583	DNA-binding transcription factor activity
AXA63_RS12820	COG1686	Belongs to the peptidase S11 family
AXA63_RS12825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXA63_RS12860	COG0616	signal peptide processing
AXA63_RS12865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXA63_RS12875	COG0573	inorganic phosphate transmembrane transporter activity
AXA63_RS12880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXA63_RS12885	COG1113	amino acid transport
AXA63_RS12890	COG3961	Belongs to the TPP enzyme family
AXA63_RS12895	COG1522	sequence-specific DNA binding
AXA63_RS12905	COG0076	glutamate decarboxylase activity
AXA63_RS12910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXA63_RS12920	COG1309	transcriptional regulator
AXA63_RS12935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXA63_RS12970	COG0352	thiamine-phosphate diphosphorylase activity
AXA63_RS12995	COG0612	Peptidase, M16
AXA63_RS13005	COG1823	symporter activity
AXA63_RS13010	COG0583	DNA-binding transcription factor activity
AXA63_RS13015	COG0477	Major facilitator Superfamily
AXA63_RS13035	COG1187	pseudouridine synthase activity
AXA63_RS13050	COG1686	Belongs to the peptidase S11 family
AXA63_RS13055	COG1252	NADH dehydrogenase
AXA63_RS13065	COG0415	Belongs to the DNA photolyase family
AXA63_RS13080	COG1215	transferase activity, transferring glycosyl groups
AXA63_RS13110	COG2070	2-Nitropropane dioxygenase
AXA63_RS13300	COG5410	chromosome segregation
AXA63_RS13495	COG0556	nucleotide-excision repair
AXA63_RS13515	COG0436	Aminotransferase
AXA63_RS13540	COG4221	oxidoreductase activity
AXA63_RS13550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXA63_RS13555	COG1381	Involved in DNA repair and RecF pathway recombination
AXA63_RS13565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXA63_RS13580	COG0681	Belongs to the peptidase S26 family
AXA63_RS13595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXA63_RS13615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXA63_RS13620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXA63_RS13625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXA63_RS13635	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXA63_RS13640	COG4208	sulfate ABC transporter
AXA63_RS13645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXA63_RS13650	COG0583	DNA-binding transcription factor activity
AXA63_RS13655	COG4625	pathogenesis
AXA63_RS13670	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXA63_RS13685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXA63_RS13695	COG1051	belongs to the nudix hydrolase family
AXA63_RS13695	COG1056	cytidyltransferase-related domain
AXA63_RS13700	COG1024	Enoyl-CoA hydratase
AXA63_RS13715	COG2814	Major facilitator Superfamily
AXA63_RS13720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXA63_RS13720	COG0047	phosphoribosylformylglycinamidine synthase activity
AXA63_RS13740	COG1473	amidohydrolase
AXA63_RS13745	COG0824	Thioesterase
AXA63_RS13765	COG0823	Involved in the tonB-independent uptake of proteins
AXA63_RS13785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXA63_RS13835	COG0628	permease
AXA63_RS13845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXA63_RS13850	COG0596	Alpha beta hydrolase
AXA63_RS13855	COG0616	signal peptide processing
AXA63_RS13855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXA63_RS13865	COG2333	competence protein COMEC
AXA63_RS13865	COG0658	competence protein
AXA63_RS13870	COG1136	(ABC) transporter
AXA63_RS13875	COG4591	ABC-type transport system involved in lipoprotein release permease component
AXA63_RS13905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA63_RS13925	COG0463	Glycosyl transferase, family 2
AXA63_RS13955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXA63_RS13960	COG1280	lysine exporter protein (LysE YggA)
AXA63_RS13970	COG0019	diaminopimelate decarboxylase activity
AXA63_RS13980	COG1113	amino acid transport
AXA63_RS13995	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AXA63_RS14005	COG3339	Conserved Protein
AXA63_RS14010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXA63_RS14015	COG0243	molybdopterin cofactor binding
AXA63_RS14020	COG1929	Belongs to the glycerate kinase type-1 family
AXA63_RS14035	COG0778	Nitroreductase
AXA63_RS14060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA63_RS14075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXA63_RS14095	COG0741	lytic transglycosylase activity
AXA63_RS14115	COG0584	glycerophosphoryl diester phosphodiesterase
AXA63_RS14145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXA63_RS14150	COG1597	lipid kinase activity
AXA63_RS14165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXA63_RS14170	COG0477	Major facilitator Superfamily
AXA63_RS14220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXA63_RS14225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXA63_RS14250	COG0505	Belongs to the CarA family
AXA63_RS14270	COG0589	response to stress
AXA63_RS14285	COG2843	Capsule synthesis protein
AXA63_RS14310	COG2321	neutral zinc metallopeptidase
AXA63_RS14315	COG2354	Protein conserved in bacteria
AXA63_RS14335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXA63_RS14350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXA63_RS14355	COG1053	succinate dehydrogenase
AXA63_RS14360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXA63_RS14365	COG2009	succinate dehydrogenase
AXA63_RS14405	COG2921	Belongs to the UPF0250 family
AXA63_RS14410	COG0321	lipoyl(octanoyl) transferase activity
AXA63_RS14425	COG0531	amino acid
AXA63_RS14435	COG1733	regulation of RNA biosynthetic process
AXA63_RS14440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXA63_RS14445	COG1648	precorrin-2 dehydrogenase activity
AXA63_RS14445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXA63_RS14460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXA63_RS14490	COG0671	phosphoesterase, PA-phosphatase related
AXA63_RS14495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA63_RS14505	COG1538	Outer membrane efflux protein
AXA63_RS14510	COG0393	Putative heavy-metal-binding
AXA63_RS14515	COG0393	Putative heavy-metal-binding
AXA63_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS14535	COG0525	valine-tRNA ligase activity
AXA63_RS14555	COG0583	DNA-binding transcription factor activity
AXA63_RS14560	COG0004	ammonium transporteR
AXA63_RS14570	COG0642	Histidine kinase
AXA63_RS14575	COG0745	RESPONSE REGULATOR receiver
AXA63_RS14580	COG2194	sulfuric ester hydrolase activity
AXA63_RS14600	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXA63_RS14615	COG2315	Protein conserved in bacteria
AXA63_RS14620	COG0142	geranyltranstransferase activity
AXA63_RS14625	COG2828	Protein conserved in bacteria
AXA63_RS14630	COG1113	amino acid transport
AXA63_RS14650	COG2207	Transcriptional regulator
AXA63_RS14675	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXA63_RS14685	COG0560	Phosphoserine phosphatase
AXA63_RS14695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXA63_RS14705	COG1530	ribonuclease E activity
AXA63_RS14710	COG0424	maF-like protein
AXA63_RS14715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AXA63_RS14720	COG1792	Involved in formation and maintenance of cell shape
AXA63_RS14725	COG1077	Cell shape determining protein MreB Mrl
AXA63_RS14730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXA63_RS14740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXA63_RS14770	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AXA63_RS14775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXA63_RS14780	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXA63_RS14785	COG1115	amino acid carrier protein
AXA63_RS14800	COG2814	Major facilitator Superfamily
AXA63_RS14805	COG1289	transmembrane transporter activity
AXA63_RS14815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AXA63_RS14855	COG1376	ErfK ybiS ycfS ynhG family protein
AXA63_RS14860	COG2832	Protein of unknown function (DUF454)
AXA63_RS14870	COG5510	response to toxic substance
AXA63_RS14890	COG0840	transmembrane signaling receptor activity
AXA63_RS14930	COG3422	double-strand break repair
AXA63_RS14935	COG2824	Alkylphosphonate utilization operon protein PhnA
AXA63_RS14940	COG3189	MarR family transcriptional regulator
AXA63_RS14950	COG0354	folic acid binding
AXA63_RS14955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXA63_RS14965	COG0679	Auxin Efflux Carrier
AXA63_RS14970	COG1902	pentaerythritol trinitrate reductase activity
AXA63_RS14975	COG4772	TonB-dependent receptor
AXA63_RS14990	COG4772	TonB-dependent receptor
AXA63_RS14995	COG2094	Belongs to the DNA glycosylase MPG family
AXA63_RS15020	COG1217	gtp-binding protein TYPA
AXA63_RS15025	COG2233	PERMEase
AXA63_RS15035	COG0833	amino acid
AXA63_RS15040	COG1690	Belongs to the RtcB family
AXA63_RS15050	COG2885	chlorophyll binding
AXA63_RS15050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXA63_RS15060	COG0183	Belongs to the thiolase family
AXA63_RS15080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXA63_RS15100	COG2207	Transcriptional regulator
AXA63_RS15105	COG0183	Belongs to the thiolase family
AXA63_RS15135	COG1272	protein, Hemolysin III
AXA63_RS15140	COG0477	Major facilitator Superfamily
AXA63_RS15155	COG0450	alkyl hydroperoxide reductase
AXA63_RS15175	COG0285	dihydrofolate synthase activity
AXA63_RS15225	COG2096	Adenosyltransferase
AXA63_RS15245	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AXA63_RS15250	COG0745	RESPONSE REGULATOR receiver
AXA63_RS15255	COG2205	protein histidine kinase activity
AXA63_RS15265	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS15270	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS15275	COG0583	DNA-binding transcription factor activity
AXA63_RS15280	COG0625	glutathione transferase activity
AXA63_RS15345	COG0438	transferase activity, transferring glycosyl groups
AXA63_RS15350	COG0463	Glycosyl transferase, family 2
AXA63_RS15355	COG0726	polysaccharide deacetylase
AXA63_RS15375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXA63_RS15380	COG2205	protein histidine kinase activity
AXA63_RS15410	COG1862	Preprotein translocase
AXA63_RS15420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXA63_RS15425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXA63_RS15435	COG3781	membrane
AXA63_RS15440	COG0613	PHP domain protein
AXA63_RS15450	COG2350	Protein conserved in bacteria
AXA63_RS15480	COG1607	acyl-coa hydrolase
AXA63_RS15540	COG2199	diguanylate cyclase activity
AXA63_RS15550	COG1408	metallophosphoesterase
AXA63_RS15555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXA63_RS15565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXA63_RS15585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXA63_RS15590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXA63_RS15605	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXA63_RS15615	COG2969	positive regulation of protein catabolic process
AXA63_RS15635	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS15640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXA63_RS15655	COG1309	transcriptional regulator
AXA63_RS15660	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS15705	COG1183	phosphatidylcholine synthase activity
AXA63_RS15710	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXA63_RS15740	COG1196	nuclear chromosome segregation
AXA63_RS15740	COG0739	heme binding
AXA63_RS15740	COG0741	lytic transglycosylase activity
AXA63_RS15750	COG1702	phosphate starvation-inducible protein PhoH
AXA63_RS15785	COG1295	ribonuclease BN
AXA63_RS15790	COG0697	spore germination
AXA63_RS15795	COG2169	Transcriptional regulator
AXA63_RS15800	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXA63_RS15845	COG0557	exoribonuclease II activity
AXA63_RS15850	COG0339	signal peptide processing
AXA63_RS15855	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AXA63_RS15885	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AXA63_RS15890	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS16045	COG0626	cystathionine gamma-synthase activity
AXA63_RS16050	COG0433	COG0433 Predicted ATPase
AXA63_RS16055	COG1017	nitric oxide dioxygenase activity
AXA63_RS16055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXA63_RS16060	COG1959	2 iron, 2 sulfur cluster binding
AXA63_RS16075	COG1301	dicarboxylic acid transport
AXA63_RS16080	COG1946	Acyl-CoA thioesterase
AXA63_RS16100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXA63_RS16105	COG1040	competence protein
AXA63_RS16110	COG0494	nUDIX hydrolase
AXA63_RS16115	COG1611	Belongs to the LOG family
AXA63_RS16135	COG0598	Magnesium transport protein CorA
AXA63_RS16145	COG2854	intermembrane phospholipid transfer
AXA63_RS16155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXA63_RS16160	COG1127	ABC transporter
AXA63_RS16170	COG0513	Belongs to the DEAD box helicase family
AXA63_RS16190	COG0408	coproporphyrinogen oxidase activity
AXA63_RS16205	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS16215	COG1983	PspC domain protein
AXA63_RS16220	COG0517	IMP dehydrogenase activity
AXA63_RS16265	COG0583	DNA-binding transcription factor activity
AXA63_RS16305	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS16315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXA63_RS16320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXA63_RS16325	COG0833	amino acid
AXA63_RS16355	COG1192	Involved in chromosome partitioning
AXA63_RS16360	COG0628	permease
AXA63_RS16370	COG1289	transmembrane transporter activity
AXA63_RS16385	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXA63_RS16390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AXA63_RS16400	COG0277	FAD linked oxidase domain protein
AXA63_RS16405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXA63_RS16430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXA63_RS16435	COG5380	lipid catabolic process
AXA63_RS16455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXA63_RS16505	COG0194	GDP metabolic process
AXA63_RS16515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXA63_RS16535	COG3307	-O-antigen
AXA63_RS16555	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AXA63_RS16560	COG1704	LemA family
AXA63_RS16570	COG0493	'glutamate synthase
AXA63_RS16575	COG0067	glutamate synthase
AXA63_RS16575	COG0069	glutamate synthase activity
AXA63_RS16575	COG0070	glutamate synthase
AXA63_RS16625	COG2226	methyltransferase
AXA63_RS16640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXA63_RS16645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXA63_RS16690	COG0833	amino acid
AXA63_RS16770	COG0488	(ABC) transporter
AXA63_RS16775	COG2873	o-acetylhomoserine
AXA63_RS16780	COG4221	oxidoreductase activity
AXA63_RS16785	COG0659	secondary active sulfate transmembrane transporter activity
AXA63_RS16805	COG0427	acetyl-CoA hydrolase
AXA63_RS16835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXA63_RS16865	COG2329	Antibiotic biosynthesis monooxygenase
AXA63_RS16880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXA63_RS16945	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXA63_RS16950	COG1733	regulation of RNA biosynthetic process
AXA63_RS16980	COG0667	Aldo Keto reductase
AXA63_RS17000	COG0583	DNA-binding transcription factor activity
AXA63_RS17005	COG2814	Major facilitator Superfamily
AXA63_RS17035	COG1335	isochorismatase
AXA63_RS17045	COG1012	belongs to the aldehyde dehydrogenase family
AXA63_RS17050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXA63_RS17060	COG1113	amino acid transport
AXA63_RS17070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXA63_RS17085	COG2814	Major facilitator Superfamily
AXA63_RS17095	COG0351	phosphomethylpyrimidine kinase
AXA63_RS17095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXA63_RS17095	COG0352	thiamine-phosphate diphosphorylase activity
AXA63_RS17115	COG1309	transcriptional regulator
AXA63_RS17120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXA63_RS17140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXA63_RS17150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXA63_RS17155	COG3162	membrane
AXA63_RS17160	COG2205	protein histidine kinase activity
AXA63_RS17160	COG0784	Response regulator, receiver
AXA63_RS17160	COG2198	Histidine kinase
AXA63_RS17185	COG3328	transposase activity
AXA63_RS17190	COG1522	sequence-specific DNA binding
AXA63_RS17195	COG1335	isochorismatase
AXA63_RS17200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXA63_RS17210	COG0668	transmembrane transport
AXA63_RS17215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXA63_RS17220	COG1519	Transferase
AXA63_RS17225	COG1902	pentaerythritol trinitrate reductase activity
AXA63_RS17245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXA63_RS17270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXA63_RS17270	COG0426	domain, Protein
AXA63_RS17275	COG4774	siderophore transport
AXA63_RS17280	COG2119	membrane
AXA63_RS17290	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXA63_RS17300	COG4942	peptidase
AXA63_RS17315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXA63_RS17325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXA63_RS17345	COG0189	ligase activity
AXA63_RS17365	COG0708	Exodeoxyribonuclease III
AXA63_RS17370	COG1393	Belongs to the ArsC family
AXA63_RS17385	COG3706	GGDEF domain
AXA63_RS17420	COG2351	hydroxyisourate hydrolase activity
AXA63_RS17425	COG2233	PERMEase
AXA63_RS17435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXA63_RS17445	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AXA63_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS17460	COG3150	esterase
AXA63_RS17480	COG0791	NLP P60 protein
AXA63_RS17480	COG1388	LysM domain
AXA63_RS17495	COG2918	glutathione biosynthetic process
AXA63_RS17510	COG2733	membrane
AXA63_RS17515	COG0436	Aminotransferase
AXA63_RS17520	COG0534	Mate efflux family protein
AXA63_RS17620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AXA63_RS17625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXA63_RS17635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXA63_RS17640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AXA63_RS17655	COG0010	Belongs to the arginase family
AXA63_RS17685	COG2188	Transcriptional regulator
AXA63_RS17695	COG0523	cobalamin synthesis protein
AXA63_RS17705	COG1113	amino acid transport
AXA63_RS17715	COG0625	glutathione transferase activity
AXA63_RS17735	COG1683	Conserved Protein
AXA63_RS17740	COG0534	Mate efflux family protein
AXA63_RS17745	COG0385	Bile acid
AXA63_RS17750	COG1335	isochorismatase
AXA63_RS17755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXA63_RS17775	COG2116	formate transmembrane transporter activity
AXA63_RS17780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXA63_RS17785	COG2133	pyrroloquinoline quinone binding
AXA63_RS17790	COG2983	Belongs to the UPF0260 family
AXA63_RS17810	COG1194	a g-specific adenine glycosylase
AXA63_RS17825	COG2818	Glycosylase
AXA63_RS17830	COG1064	alcohol dehydrogenase
AXA63_RS17835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXA63_RS17845	COG0583	DNA-binding transcription factor activity
AXA63_RS17850	COG0656	L-ascorbic acid biosynthetic process
AXA63_RS17855	COG2814	Major facilitator Superfamily
AXA63_RS17890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXA63_RS17905	COG2233	PERMEase
AXA63_RS17960	COG0733	neurotransmitter:sodium symporter activity
AXA63_RS18000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXA63_RS18005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXA63_RS18010	COG0596	Alpha beta hydrolase
AXA63_RS18035	COG0488	(ABC) transporter
AXA63_RS18040	COG0586	Pfam SNARE associated Golgi protein
AXA63_RS18050	COG0187	DNA topoisomerase II activity
AXA63_RS18060	COG0592	DNA-directed DNA polymerase activity
AXA63_RS18085	COG0706	membrane insertase activity
AXA63_RS18100	COG1230	cation diffusion facilitator family transporter
AXA63_RS18105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXA63_RS18125	COG0402	S-adenosylhomocysteine deaminase activity
AXA63_RS18135	COG0754	glutathionylspermidine amidase activity
AXA63_RS18145	COG0861	Integral membrane protein TerC family
AXA63_RS18150	COG0671	phosphoesterase, PA-phosphatase related
AXA63_RS18160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXA63_RS18175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXA63_RS18180	COG2951	lytic endotransglycosylase activity
AXA63_RS18210	COG0583	DNA-binding transcription factor activity
AXA63_RS18230	COG0657	acetylesterase activity
AXA63_RS18235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXA63_RS18275	COG1047	Peptidyl-prolyl cis-trans
AXA63_RS18285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXA63_RS18290	COG0196	riboflavin kinase activity
AXA63_RS18300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXA63_RS18305	COG1309	transcriptional regulator
AXA63_RS18310	COG1116	anion transmembrane transporter activity
AXA63_RS18315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXA63_RS18320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXA63_RS18325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXA63_RS18330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXA63_RS18350	COG1028	Short-chain dehydrogenase reductase Sdr
AXA63_RS18355	COG0546	phosphoglycolate phosphatase activity
AXA63_RS18410	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXA63_RS18415	COG0728	peptidoglycan biosynthetic process
AXA63_RS18440	COG1596	polysaccharide export
AXA63_RS18445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AXA63_RS18505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXA63_RS18510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXA63_RS18515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXA63_RS18530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXA63_RS18535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXA63_RS18545	COG2186	Transcriptional regulator
AXA63_RS18555	COG0277	FAD linked oxidase domain protein
AXA63_RS18560	COG1448	Aminotransferase
AXA63_RS18565	COG1802	Transcriptional regulator
AXA63_RS18580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXA63_RS18640	COG0564	pseudouridine synthase activity
AXA63_RS18680	COG0251	oxidation-reduction process
AXA63_RS18685	COG1113	amino acid transport
AXA63_RS18690	COG1113	amino acid transport
AXA63_RS18710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXA63_RS18715	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS18720	COG1024	Enoyl-CoA hydratase
AXA63_RS18725	COG1024	Enoyl-CoA hydratase
AXA63_RS18730	COG0477	Major facilitator Superfamily
AXA63_RS18735	COG3916	Acyl-homoserine-lactone synthase
AXA63_RS18745	COG2197	response regulator
AXA63_RS18760	COG1960	acyl-CoA dehydrogenase activity
AXA63_RS18765	COG3321	synthase
AXA63_RS18765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AXA63_RS18765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXA63_RS18765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXA63_RS18805	COG0271	Belongs to the BolA IbaG family
AXA63_RS18815	COG1192	Involved in chromosome partitioning
AXA63_RS18830	COG0586	Pfam SNARE associated Golgi protein
AXA63_RS18835	COG2259	Doxx family
AXA63_RS18840	COG4399	Belongs to the UPF0754 family
AXA63_RS18845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXA63_RS18845	COG0519	Catalyzes the synthesis of GMP from XMP
AXA63_RS18890	COG0281	malic enzyme
AXA63_RS18895	COG2837	iron assimilation
AXA63_RS18900	COG1280	lysine exporter protein (LysE YggA)
AXA63_RS18905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXA63_RS18910	COG1121	(ABC) transporter
AXA63_RS18975	COG0386	Belongs to the glutathione peroxidase family
AXA63_RS18990	COG1309	transcriptional regulator
AXA63_RS18995	COG0697	spore germination
AXA63_RS19005	COG0758	DNA mediated transformation
AXA63_RS19040	COG1309	transcriptional regulator
AXA63_RS19075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXA63_RS19085	COG0655	NAD(P)H dehydrogenase (quinone) activity
AXA63_RS19120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXA63_RS19140	COG1253	flavin adenine dinucleotide binding
AXA63_RS19150	COG2860	membrane
AXA63_RS19155	COG0477	Major facilitator Superfamily
AXA63_RS19165	COG0318	PFAM AMP-dependent synthetase and ligase
AXA63_RS19180	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXA63_RS19195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXA63_RS19205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXA63_RS19210	COG0606	chelatase, subunit chli
AXA63_RS19240	COG0589	response to stress
AXA63_RS19245	COG0659	secondary active sulfate transmembrane transporter activity
AXA63_RS19255	COG0606	chelatase, subunit chli
AXA63_RS19265	COG0347	Belongs to the P(II) protein family
AXA63_RS19270	COG0004	ammonium transporteR
AXA63_RS19280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXA63_RS19280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXA63_RS19320	COG0795	lipopolysaccharide-transporting ATPase activity
AXA63_RS19325	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AXA63_RS19330	COG0793	Belongs to the peptidase S41A family
AXA63_RS19345	COG2197	response regulator
AXA63_RS19355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXA63_RS19365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXA63_RS19370	COG4974	Belongs to the 'phage' integrase family
AXA63_RS19395	COG0772	Belongs to the SEDS family
AXA63_RS19400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXA63_RS19405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXA63_RS19410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXA63_RS19435	COG0697	spore germination
AXA63_RS19440	COG1538	Outer membrane efflux protein
AXA63_RS19460	COG3275	phosphorelay sensor kinase activity
AXA63_RS19470	COG0181	hydroxymethylbilane synthase activity
AXA63_RS19515	COG1716	ATPase activity
AXA63_RS19520	COG0546	phosphoglycolate phosphatase activity
AXA63_RS19615	COG0596	Alpha beta hydrolase
AXA63_RS19620	COG2056	Na+-H+ antiporter family
AXA63_RS19635	COG0326	Molecular chaperone. Has ATPase activity
AXA63_RS19850	COG0741	lytic transglycosylase activity
AXA63_RS19885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXA63_RS20055	COG1525	nuclease
AXA63_RS20125	COG1475	DNA binding