locus-tag	class	description
LRO55_RS00010	COG0592	DNA-directed DNA polymerase activity
LRO55_RS00020	COG0187	DNA topoisomerase II activity
LRO55_RS00035	COG0488	(ABC) transporter
LRO55_RS00060	COG0596	Alpha beta hydrolase
LRO55_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LRO55_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LRO55_RS00120	COG0733	neurotransmitter:sodium symporter activity
LRO55_RS00130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LRO55_RS00160	COG2233	PERMEase
LRO55_RS00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS00210	COG2814	Major facilitator Superfamily
LRO55_RS00215	COG0656	L-ascorbic acid biosynthetic process
LRO55_RS00220	COG0583	DNA-binding transcription factor activity
LRO55_RS00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRO55_RS00240	COG1064	alcohol dehydrogenase
LRO55_RS00245	COG2818	Glycosylase
LRO55_RS00260	COG1194	a g-specific adenine glycosylase
LRO55_RS00280	COG2983	Belongs to the UPF0260 family
LRO55_RS00285	COG2133	pyrroloquinoline quinone binding
LRO55_RS00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LRO55_RS00295	COG2116	formate transmembrane transporter activity
LRO55_RS00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRO55_RS00320	COG1335	isochorismatase
LRO55_RS00325	COG0385	Bile acid
LRO55_RS00330	COG0534	Mate efflux family protein
LRO55_RS00335	COG1683	Conserved Protein
LRO55_RS00350	COG0346	lactoylglutathione lyase activity
LRO55_RS00355	COG0625	glutathione transferase activity
LRO55_RS00365	COG1113	amino acid transport
LRO55_RS00375	COG0523	cobalamin synthesis protein
LRO55_RS00385	COG2188	Transcriptional regulator
LRO55_RS00415	COG0010	Belongs to the arginase family
LRO55_RS00425	COG0546	phosphoglycolate phosphatase activity
LRO55_RS00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LRO55_RS00435	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS00445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LRO55_RS00455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LRO55_RS00460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LRO55_RS00525	COG1910	domain protein
LRO55_RS00560	COG0534	Mate efflux family protein
LRO55_RS00565	COG0436	Aminotransferase
LRO55_RS00570	COG2733	membrane
LRO55_RS00585	COG2918	glutathione biosynthetic process
LRO55_RS00600	COG3179	chitinase
LRO55_RS00620	COG3150	esterase
LRO55_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LRO55_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRO55_RS00650	COG2233	PERMEase
LRO55_RS00655	COG2351	hydroxyisourate hydrolase activity
LRO55_RS00690	COG3706	GGDEF domain
LRO55_RS00705	COG1393	Belongs to the ArsC family
LRO55_RS00710	COG0708	Exodeoxyribonuclease III
LRO55_RS00730	COG0189	ligase activity
LRO55_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LRO55_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LRO55_RS00775	COG4942	peptidase
LRO55_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
LRO55_RS00795	COG2119	membrane
LRO55_RS00800	COG4774	siderophore transport
LRO55_RS00825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LRO55_RS00850	COG1902	pentaerythritol trinitrate reductase activity
LRO55_RS00855	COG1519	Transferase
LRO55_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LRO55_RS00865	COG0668	transmembrane transport
LRO55_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LRO55_RS00880	COG1335	isochorismatase
LRO55_RS00885	COG1522	sequence-specific DNA binding
LRO55_RS00910	COG0784	Response regulator, receiver
LRO55_RS00910	COG2198	Histidine kinase
LRO55_RS00910	COG2205	protein histidine kinase activity
LRO55_RS00915	COG3162	membrane
LRO55_RS00920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LRO55_RS00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LRO55_RS00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LRO55_RS00950	COG1309	transcriptional regulator
LRO55_RS00970	COG0300	oxidoreductase activity
LRO55_RS00975	COG0789	Transcriptional regulator
LRO55_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
LRO55_RS00980	COG0351	phosphomethylpyrimidine kinase
LRO55_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LRO55_RS00990	COG2814	Major facilitator Superfamily
LRO55_RS00995	COG0629	single-stranded DNA binding
LRO55_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LRO55_RS01015	COG1113	amino acid transport
LRO55_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LRO55_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS01040	COG1335	isochorismatase
LRO55_RS01080	COG2814	Major facilitator Superfamily
LRO55_RS01085	COG0583	DNA-binding transcription factor activity
LRO55_RS01125	COG0667	Aldo Keto reductase
LRO55_RS01145	COG1129	ABC transporter
LRO55_RS01160	COG1733	regulation of RNA biosynthetic process
LRO55_RS01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRO55_RS01180	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LRO55_RS01185	COG2207	Transcriptional regulator
LRO55_RS01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LRO55_RS01260	COG2329	Antibiotic biosynthesis monooxygenase
LRO55_RS01265	COG0697	spore germination
LRO55_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LRO55_RS01325	COG0427	acetyl-CoA hydrolase
LRO55_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
LRO55_RS01355	COG4221	oxidoreductase activity
LRO55_RS01360	COG2873	o-acetylhomoserine
LRO55_RS01365	COG0488	(ABC) transporter
LRO55_RS01430	COG0833	amino acid
LRO55_RS01475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LRO55_RS01480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LRO55_RS01495	COG2226	methyltransferase
LRO55_RS01545	COG0070	glutamate synthase
LRO55_RS01545	COG0067	glutamate synthase
LRO55_RS01545	COG0069	glutamate synthase activity
LRO55_RS01550	COG0493	'glutamate synthase
LRO55_RS01560	COG1704	LemA family
LRO55_RS01565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LRO55_RS01575	COG4969	Belongs to the N-Me-Phe pilin family
LRO55_RS01585	COG3307	-O-antigen
LRO55_RS01605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LRO55_RS01620	COG0194	GDP metabolic process
LRO55_RS01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LRO55_RS01695	COG5380	lipid catabolic process
LRO55_RS01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LRO55_RS01715	COG5006	permease, DMT superfamily
LRO55_RS01720	COG5006	permease, DMT superfamily
LRO55_RS01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LRO55_RS01730	COG0277	FAD linked oxidase domain protein
LRO55_RS01745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LRO55_RS01750	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRO55_RS01770	COG1289	transmembrane transporter activity
LRO55_RS01780	COG0628	permease
LRO55_RS01785	COG1192	Involved in chromosome partitioning
LRO55_RS01815	COG0833	amino acid
LRO55_RS01820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LRO55_RS01825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LRO55_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS01875	COG0583	DNA-binding transcription factor activity
LRO55_RS01880	COG1794	racemase activity, acting on amino acids and derivatives
LRO55_RS01885	COG0583	DNA-binding transcription factor activity
LRO55_RS01910	COG0752	glycyl-tRNA synthetase alpha subunit
LRO55_RS01930	COG0517	IMP dehydrogenase activity
LRO55_RS01930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LRO55_RS01930	COG0617	tRNA 3'-terminal CCA addition
LRO55_RS01935	COG1983	PspC domain protein
LRO55_RS01945	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS01960	COG0408	coproporphyrinogen oxidase activity
LRO55_RS01980	COG0513	Belongs to the DEAD box helicase family
LRO55_RS01990	COG1127	ABC transporter
LRO55_RS01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LRO55_RS02015	COG0598	Magnesium transport protein CorA
LRO55_RS02025	COG0494	nUDIX hydrolase
LRO55_RS02030	COG1040	competence protein
LRO55_RS02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LRO55_RS02050	COG2937	Belongs to the GPAT DAPAT family
LRO55_RS02055	COG1946	Acyl-CoA thioesterase
LRO55_RS02060	COG1301	dicarboxylic acid transport
LRO55_RS02075	COG1959	2 iron, 2 sulfur cluster binding
LRO55_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRO55_RS02080	COG1017	nitric oxide dioxygenase activity
LRO55_RS02085	COG0433	COG0433 Predicted ATPase
LRO55_RS02090	COG0626	cystathionine gamma-synthase activity
LRO55_RS02105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LRO55_RS02110	COG0088	Forms part of the polypeptide exit tunnel
LRO55_RS02130	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LRO55_RS02170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LRO55_RS02245	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS02250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LRO55_RS02280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LRO55_RS02285	COG0339	signal peptide processing
LRO55_RS02290	COG0557	exoribonuclease II activity
LRO55_RS02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
LRO55_RS02340	COG1295	ribonuclease BN
LRO55_RS02375	COG1702	phosphate starvation-inducible protein PhoH
LRO55_RS02385	COG0739	heme binding
LRO55_RS02385	COG0741	lytic transglycosylase activity
LRO55_RS02385	COG1196	nuclear chromosome segregation
LRO55_RS02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LRO55_RS02420	COG1183	phosphatidylcholine synthase activity
LRO55_RS02470	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LRO55_RS02485	COG1309	transcriptional regulator
LRO55_RS02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LRO55_RS02505	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS02525	COG2969	positive regulation of protein catabolic process
LRO55_RS02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LRO55_RS02540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LRO55_RS02545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LRO55_RS02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LRO55_RS02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LRO55_RS02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LRO55_RS02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LRO55_RS02590	COG1408	metallophosphoesterase
LRO55_RS02595	COG2885	chlorophyll binding
LRO55_RS02600	COG2199	diguanylate cyclase activity
LRO55_RS02665	COG1607	acyl-coa hydrolase
LRO55_RS02695	COG2350	Protein conserved in bacteria
LRO55_RS02705	COG0613	PHP domain protein
LRO55_RS02710	COG3781	membrane
LRO55_RS02720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LRO55_RS02725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LRO55_RS02735	COG1862	Preprotein translocase
LRO55_RS02790	COG4999	Histidine kinase
LRO55_RS02790	COG3437	response regulator, receiver
LRO55_RS02790	COG3850	Histidine kinase
LRO55_RS02790	COG2205	protein histidine kinase activity
LRO55_RS02795	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LRO55_RS02815	COG0726	polysaccharide deacetylase
LRO55_RS02820	COG0463	Glycosyl transferase, family 2
LRO55_RS02825	COG0438	transferase activity, transferring glycosyl groups
LRO55_RS02840	COG1215	transferase activity, transferring glycosyl groups
LRO55_RS02840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LRO55_RS02860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LRO55_RS02895	COG0625	glutathione transferase activity
LRO55_RS02900	COG0583	DNA-binding transcription factor activity
LRO55_RS02905	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS02910	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS02920	COG2205	protein histidine kinase activity
LRO55_RS02925	COG0745	RESPONSE REGULATOR receiver
LRO55_RS02935	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LRO55_RS02955	COG2096	Adenosyltransferase
LRO55_RS03005	COG0285	dihydrofolate synthase activity
LRO55_RS03030	COG0450	alkyl hydroperoxide reductase
LRO55_RS03045	COG0477	Major facilitator Superfamily
LRO55_RS03050	COG1272	protein, Hemolysin III
LRO55_RS03060	COG2153	protein acetylation
LRO55_RS03080	COG0183	Belongs to the thiolase family
LRO55_RS03085	COG2207	Transcriptional regulator
LRO55_RS03105	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRO55_RS03125	COG0183	Belongs to the thiolase family
LRO55_RS03135	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LRO55_RS03135	COG2885	chlorophyll binding
LRO55_RS03145	COG1690	Belongs to the RtcB family
LRO55_RS03150	COG0833	amino acid
LRO55_RS03160	COG2233	PERMEase
LRO55_RS03165	COG1217	gtp-binding protein TYPA
LRO55_RS03190	COG2094	Belongs to the DNA glycosylase MPG family
LRO55_RS03195	COG4772	TonB-dependent receptor
LRO55_RS03200	COG1902	pentaerythritol trinitrate reductase activity
LRO55_RS03215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LRO55_RS03220	COG0354	folic acid binding
LRO55_RS03240	COG2233	PERMEase
LRO55_RS03245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRO55_RS03250	COG0251	oxidation-reduction process
LRO55_RS03255	COG1335	isochorismatase
LRO55_RS03260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS03265	COG0778	Nitroreductase
LRO55_RS03270	COG0596	Alpha beta hydrolase
LRO55_RS03280	COG2824	Alkylphosphonate utilization operon protein PhnA
LRO55_RS03285	COG3422	double-strand break repair
LRO55_RS03325	COG0840	transmembrane signaling receptor activity
LRO55_RS03355	COG2832	Protein of unknown function (DUF454)
LRO55_RS03360	COG1376	ErfK ybiS ycfS ynhG family protein
LRO55_RS03400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LRO55_RS03410	COG1289	transmembrane transporter activity
LRO55_RS03415	COG2814	Major facilitator Superfamily
LRO55_RS03435	COG1115	amino acid carrier protein
LRO55_RS03440	COG1752	Esterase of the alpha-beta hydrolase superfamily
LRO55_RS03445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LRO55_RS03450	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LRO55_RS03480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LRO55_RS03490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LRO55_RS03495	COG1077	Cell shape determining protein MreB Mrl
LRO55_RS03500	COG1792	Involved in formation and maintenance of cell shape
LRO55_RS03505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LRO55_RS03510	COG0424	maF-like protein
LRO55_RS03515	COG1530	ribonuclease E activity
LRO55_RS03525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRO55_RS03545	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRO55_RS03570	COG2207	Transcriptional regulator
LRO55_RS03610	COG1113	amino acid transport
LRO55_RS03615	COG2828	Protein conserved in bacteria
LRO55_RS03620	COG0142	geranyltranstransferase activity
LRO55_RS03625	COG2315	Protein conserved in bacteria
LRO55_RS03640	COG1752	Esterase of the alpha-beta hydrolase superfamily
LRO55_RS03665	COG2194	sulfuric ester hydrolase activity
LRO55_RS03670	COG0745	RESPONSE REGULATOR receiver
LRO55_RS03675	COG0642	Histidine kinase
LRO55_RS03685	COG0004	ammonium transporteR
LRO55_RS03690	COG0583	DNA-binding transcription factor activity
LRO55_RS03710	COG0525	valine-tRNA ligase activity
LRO55_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS03725	COG2223	nitrite transmembrane transporter activity
LRO55_RS03730	COG0393	Putative heavy-metal-binding
LRO55_RS03735	COG0393	Putative heavy-metal-binding
LRO55_RS03740	COG1538	Outer membrane efflux protein
LRO55_RS03750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS03755	COG0671	phosphoesterase, PA-phosphatase related
LRO55_RS03780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LRO55_RS03795	COG1648	precorrin-2 dehydrogenase activity
LRO55_RS03795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LRO55_RS03800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LRO55_RS03835	COG0531	amino acid
LRO55_RS03850	COG0321	lipoyl(octanoyl) transferase activity
LRO55_RS03855	COG2921	Belongs to the UPF0250 family
LRO55_RS03890	COG2009	succinate dehydrogenase
LRO55_RS03895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LRO55_RS03900	COG1053	succinate dehydrogenase
LRO55_RS03905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LRO55_RS03930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LRO55_RS03960	COG2354	Protein conserved in bacteria
LRO55_RS03965	COG2321	neutral zinc metallopeptidase
LRO55_RS03985	COG2843	Capsule synthesis protein
LRO55_RS04000	COG0589	response to stress
LRO55_RS04020	COG0505	Belongs to the CarA family
LRO55_RS04050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LRO55_RS04055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LRO55_RS04105	COG0477	Major facilitator Superfamily
LRO55_RS04110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LRO55_RS04125	COG1597	lipid kinase activity
LRO55_RS04130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LRO55_RS04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRO55_RS04160	COG0584	glycerophosphoryl diester phosphodiesterase
LRO55_RS04180	COG0741	lytic transglycosylase activity
LRO55_RS04195	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LRO55_RS04200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LRO55_RS04220	COG0583	DNA-binding transcription factor activity
LRO55_RS04225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRO55_RS04240	COG0789	Transcriptional regulator
LRO55_RS04300	COG0778	Nitroreductase
LRO55_RS04315	COG1929	Belongs to the glycerate kinase type-1 family
LRO55_RS04345	COG1115	amino acid carrier protein
LRO55_RS04350	COG1113	amino acid transport
LRO55_RS04360	COG0019	diaminopimelate decarboxylase activity
LRO55_RS04370	COG1397	ADP-ribosylglycohydrolase
LRO55_RS04380	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS04385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LRO55_RS04410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRO55_RS04430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS04460	COG0697	spore germination
LRO55_RS04470	COG4591	ABC-type transport system involved in lipoprotein release permease component
LRO55_RS04475	COG1136	(ABC) transporter
LRO55_RS04480	COG0658	competence protein
LRO55_RS04480	COG2333	competence protein COMEC
LRO55_RS04490	COG0616	signal peptide processing
LRO55_RS04490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LRO55_RS04500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LRO55_RS04510	COG0628	permease
LRO55_RS04545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LRO55_RS04565	COG0823	Involved in the tonB-independent uptake of proteins
LRO55_RS04585	COG0824	Thioesterase
LRO55_RS04590	COG1473	amidohydrolase
LRO55_RS04610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LRO55_RS04610	COG0047	phosphoribosylformylglycinamidine synthase activity
LRO55_RS04615	COG2814	Major facilitator Superfamily
LRO55_RS04620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LRO55_RS04625	COG1024	Enoyl-CoA hydratase
LRO55_RS04630	COG1051	belongs to the nudix hydrolase family
LRO55_RS04630	COG1056	cytidyltransferase-related domain
LRO55_RS04645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LRO55_RS04660	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LRO55_RS04665	COG0602	queuosine metabolic process
LRO55_RS04675	COG4625	pathogenesis
LRO55_RS04680	COG0583	DNA-binding transcription factor activity
LRO55_RS04685	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LRO55_RS04690	COG4208	sulfate ABC transporter
LRO55_RS04695	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LRO55_RS04705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LRO55_RS04710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LRO55_RS04715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LRO55_RS04735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LRO55_RS04745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LRO55_RS04750	COG0481	GTPase activity
LRO55_RS04755	COG0681	Belongs to the peptidase S26 family
LRO55_RS04765	COG0571	ribonuclease III activity
LRO55_RS04770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LRO55_RS04785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LRO55_RS04795	COG4221	oxidoreductase activity
LRO55_RS04825	COG0443	Heat shock 70 kDa protein
LRO55_RS04835	COG0436	Aminotransferase
LRO55_RS04855	COG0556	nucleotide-excision repair
LRO55_RS04910	COG2070	2-Nitropropane dioxygenase
LRO55_RS04940	COG1215	transferase activity, transferring glycosyl groups
LRO55_RS04955	COG0415	Belongs to the DNA photolyase family
LRO55_RS04965	COG1252	NADH dehydrogenase
LRO55_RS04970	COG1686	Belongs to the peptidase S11 family
LRO55_RS04985	COG1187	pseudouridine synthase activity
LRO55_RS05050	COG0477	Major facilitator Superfamily
LRO55_RS05055	COG0583	DNA-binding transcription factor activity
LRO55_RS05060	COG1823	symporter activity
LRO55_RS05070	COG0612	Peptidase, M16
LRO55_RS05095	COG0352	thiamine-phosphate diphosphorylase activity
LRO55_RS05130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRO55_RS05155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LRO55_RS05160	COG0076	glutamate decarboxylase activity
LRO55_RS05170	COG1522	sequence-specific DNA binding
LRO55_RS05175	COG3961	Belongs to the TPP enzyme family
LRO55_RS05180	COG1113	amino acid transport
LRO55_RS05185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LRO55_RS05190	COG0573	inorganic phosphate transmembrane transporter activity
LRO55_RS05200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LRO55_RS05205	COG0616	signal peptide processing
LRO55_RS05240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LRO55_RS05245	COG1686	Belongs to the peptidase S11 family
LRO55_RS05265	COG1388	LysM domain
LRO55_RS05265	COG4942	peptidase
LRO55_RS05270	COG0583	DNA-binding transcription factor activity
LRO55_RS05275	COG1067	ATP-dependent peptidase activity
LRO55_RS05295	COG0254	rRNA binding
LRO55_RS05315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LRO55_RS05320	COG1966	Carbon starvation protein
LRO55_RS05325	COG2879	small protein
LRO55_RS05385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LRO55_RS05390	COG2423	ornithine cyclodeaminase activity
LRO55_RS05400	COG2964	Protein conserved in bacteria
LRO55_RS05410	COG1741	Belongs to the pirin family
LRO55_RS05425	COG3739	integral membrane protein
LRO55_RS05445	COG0302	gtp cyclohydrolase
LRO55_RS05455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LRO55_RS05490	COG0512	Glutamine amidotransferase of anthranilate synthase
LRO55_RS05510	COG0174	glutamine synthetase
LRO55_RS05520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LRO55_RS05555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LRO55_RS05560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LRO55_RS05565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LRO55_RS05575	COG0281	malic enzyme
LRO55_RS05575	COG0280	phosphate acetyltransferase
LRO55_RS05585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LRO55_RS05590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LRO55_RS05595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LRO55_RS05610	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS05615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LRO55_RS05620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LRO55_RS05630	COG2223	nitrite transmembrane transporter activity
LRO55_RS05640	COG0024	Methionine aminopeptidase
LRO55_RS05645	COG0052	Belongs to the universal ribosomal protein uS2 family
LRO55_RS05660	COG2207	Transcriptional regulator
LRO55_RS05685	COG2951	lytic endotransglycosylase activity
LRO55_RS05690	COG0772	Belongs to the SEDS family
LRO55_RS05705	COG0842	Transport permease protein
LRO55_RS05710	COG1131	(ABC) transporter
LRO55_RS05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS05775	COG4160	amino acid transport
LRO55_RS05780	COG4598	ABC transporter
LRO55_RS05790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRO55_RS05795	COG0384	phenazine biosynthesis protein PhzF
LRO55_RS05805	COG1720	tRNA m6t6A37 methyltransferase activity
LRO55_RS05815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LRO55_RS05830	COG0642	Histidine kinase
LRO55_RS05840	COG0494	nUDIX hydrolase
LRO55_RS05850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LRO55_RS05855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LRO55_RS05860	COG3139	Protein of unknown function (DUF1315)
LRO55_RS05870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LRO55_RS05875	COG1301	dicarboxylic acid transport
LRO55_RS05880	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS05890	COG2819	hydrolase of the alpha beta superfamily
LRO55_RS05900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LRO55_RS05910	COG2195	Cleaves the N-terminal amino acid of tripeptides
LRO55_RS05930	COG1690	Belongs to the RtcB family
LRO55_RS05935	COG1234	tRNA 3'-trailer cleavage
LRO55_RS05940	COG4650	regulator
LRO55_RS05970	COG2363	Small membrane protein
LRO55_RS05995	COG0513	Belongs to the DEAD box helicase family
LRO55_RS06005	COG0778	Nitroreductase
LRO55_RS06035	COG1286	toxin biosynthetic process
LRO55_RS06065	COG1610	YqeY-like protein
LRO55_RS06120	COG1278	Cold shock
LRO55_RS06145	COG0534	Mate efflux family protein
LRO55_RS06155	COG1309	transcriptional regulator
LRO55_RS06165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRO55_RS06170	COG4221	oxidoreductase activity
LRO55_RS06175	COG1733	regulation of RNA biosynthetic process
LRO55_RS06180	COG2085	NADP oxidoreductase coenzyme F420-dependent
LRO55_RS06210	COG3243	poly(R)-hydroxyalkanoic acid synthase
LRO55_RS06215	COG0786	glutamate:sodium symporter activity
LRO55_RS06220	COG0475	glutathione-regulated potassium exporter activity
LRO55_RS06220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LRO55_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS06235	COG0477	Major facilitator Superfamily
LRO55_RS06265	COG0583	DNA-binding transcription factor activity
LRO55_RS06275	COG2995	paraquat-inducible protein a
LRO55_RS06280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LRO55_RS06280	COG3008	intermembrane lipid transfer
LRO55_RS06290	COG2351	hydroxyisourate hydrolase activity
LRO55_RS06315	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LRO55_RS06320	COG1794	racemase activity, acting on amino acids and derivatives
LRO55_RS06330	COG2175	clavaminate synthase activity
LRO55_RS06335	COG3246	L-lysine catabolic process to acetate
LRO55_RS06355	COG2855	membrane
LRO55_RS06390	COG2814	Major facilitator Superfamily
LRO55_RS06405	COG0625	glutathione transferase activity
LRO55_RS06420	COG1301	dicarboxylic acid transport
LRO55_RS06435	COG2011	ABC-type metal ion transport system permease component
LRO55_RS06440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LRO55_RS06445	COG1464	Belongs to the NlpA lipoprotein family
LRO55_RS06450	COG0151	Belongs to the GarS family
LRO55_RS06455	COG0138	bifunctional purine biosynthesis protein purh
LRO55_RS06460	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LRO55_RS06490	COG2308	Evidence 4 Homologs of previously reported genes of
LRO55_RS06500	COG1305	Transglutaminase-like
LRO55_RS06510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LRO55_RS06515	COG0305	Participates in initiation and elongation during chromosome replication
LRO55_RS06540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LRO55_RS06550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LRO55_RS06580	COG0726	polysaccharide deacetylase
LRO55_RS06580	COG1649	PFAM Uncharacterised BCR, COG1649
LRO55_RS06585	COG1215	transferase activity, transferring glycosyl groups
LRO55_RS06590	COG3658	cytochrome
LRO55_RS06600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS06615	COG0583	DNA-binding transcription factor activity
LRO55_RS06635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS06640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRO55_RS06655	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS06660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRO55_RS06675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LRO55_RS06685	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LRO55_RS06690	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LRO55_RS06700	COG2205	protein histidine kinase activity
LRO55_RS06705	COG0745	RESPONSE REGULATOR receiver
LRO55_RS06710	COG0174	glutamine synthetase
LRO55_RS06730	COG0729	surface antigen
LRO55_RS06740	COG2706	6-phosphogluconolactonase activity
LRO55_RS06760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LRO55_RS06765	COG2814	Major facilitator Superfamily
LRO55_RS06780	COG0583	DNA-binding transcription factor activity
LRO55_RS06795	COG1187	pseudouridine synthase activity
LRO55_RS06815	COG0802	atpase or kinase
LRO55_RS06820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LRO55_RS06830	COG1923	regulation of RNA biosynthetic process
LRO55_RS06835	COG0697	spore germination
LRO55_RS06850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LRO55_RS06860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LRO55_RS06865	COG0519	Catalyzes the synthesis of GMP from XMP
LRO55_RS06865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LRO55_RS06870	COG4302	ethanolamine ammonia-lyase activity
LRO55_RS06875	COG4303	Ethanolamine ammonia lyase large subunit
LRO55_RS06880	COG0531	amino acid
LRO55_RS06900	COG1454	alcohol dehydrogenase
LRO55_RS06905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LRO55_RS06930	COG0308	aminopeptidase N
LRO55_RS06970	COG1605	Chorismate mutase
LRO55_RS06975	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS06995	COG2205	protein histidine kinase activity
LRO55_RS07060	COG1733	regulation of RNA biosynthetic process
LRO55_RS07080	COG0583	DNA-binding transcription factor activity
LRO55_RS07095	COG3111	PFAM Bacterial OB fold (BOF) protein
LRO55_RS07115	COG0488	(ABC) transporter
LRO55_RS07120	COG0589	response to stress
LRO55_RS07140	COG3135	benzoate transporter
LRO55_RS07145	COG1522	sequence-specific DNA binding
LRO55_RS07155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LRO55_RS07160	COG0583	DNA-binding transcription factor activity
LRO55_RS07170	COG0183	Belongs to the thiolase family
LRO55_RS07180	COG2030	dehydratase
LRO55_RS07210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LRO55_RS07220	COG0824	Thioesterase
LRO55_RS07225	COG1454	alcohol dehydrogenase
LRO55_RS07245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LRO55_RS07275	COG0069	glutamate synthase activity
LRO55_RS07305	COG2814	Major facilitator Superfamily
LRO55_RS07320	COG0511	ligase activity, forming carbon-carbon bonds
LRO55_RS07355	COG2814	Major facilitator Superfamily
LRO55_RS07365	COG4264	IucA IucC family
LRO55_RS07395	COG1116	anion transmembrane transporter activity
LRO55_RS07395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRO55_RS07410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRO55_RS07410	COG2146	nitrite reductase [NAD(P)H] activity
LRO55_RS07415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRO55_RS07420	COG0243	molybdopterin cofactor binding
LRO55_RS07430	COG0243	molybdopterin cofactor binding
LRO55_RS07450	COG0521	Mo-molybdopterin cofactor biosynthetic process
LRO55_RS07450	COG0315	cyclic pyranopterin monophosphate synthase activity
LRO55_RS07455	COG0303	'Molybdopterin
LRO55_RS07465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRO55_RS07470	COG0697	spore germination
LRO55_RS07495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LRO55_RS07515	COG1335	isochorismatase
LRO55_RS07555	COG2204	response regulator
LRO55_RS07560	COG3852	Histidine kinase
LRO55_RS07585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LRO55_RS07590	COG0575	Belongs to the CDS family
LRO55_RS07625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LRO55_RS07640	COG2137	regulation of response to DNA damage stimulus
LRO55_RS07650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LRO55_RS07655	COG1011	Hydrolase
LRO55_RS07670	COG1522	sequence-specific DNA binding
LRO55_RS07680	COG1113	amino acid transport
LRO55_RS07705	COG0659	secondary active sulfate transmembrane transporter activity
LRO55_RS07720	COG5001	Diguanylate cyclase
LRO55_RS07720	COG3300	MHYT domain
LRO55_RS07755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LRO55_RS07755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LRO55_RS07755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LRO55_RS07760	COG1105	Belongs to the carbohydrate kinase PfkB family
LRO55_RS07765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LRO55_RS07765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LRO55_RS07795	COG0024	Methionine aminopeptidase
LRO55_RS07800	COG0583	DNA-binding transcription factor activity
LRO55_RS07815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LRO55_RS07820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LRO55_RS07820	COG0517	IMP dehydrogenase activity
LRO55_RS07845	COG0552	protein localization to endoplasmic reticulum
LRO55_RS07855	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LRO55_RS07865	COG4890	Cyd operon protein YbgT
LRO55_RS07870	COG1294	oxidase, subunit
LRO55_RS07885	COG1585	Membrane protein implicated in regulation of membrane protease activity
LRO55_RS07895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LRO55_RS07900	COG4774	siderophore transport
LRO55_RS07915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LRO55_RS07920	COG0569	domain protein
LRO55_RS07925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LRO55_RS07955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LRO55_RS07960	COG0542	response to heat
LRO55_RS07970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LRO55_RS07985	COG1902	pentaerythritol trinitrate reductase activity
LRO55_RS07985	COG0446	pyridine nucleotide-disulphide oxidoreductase
LRO55_RS08025	COG0148	phosphopyruvate hydratase activity
LRO55_RS08030	COG2323	membrane
LRO55_RS08045	COG4773	Receptor
LRO55_RS08050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LRO55_RS08060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LRO55_RS08065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LRO55_RS08070	COG0183	Belongs to the thiolase family
LRO55_RS08075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LRO55_RS08080	COG0596	Alpha beta hydrolase
LRO55_RS08085	COG2271	Major facilitator Superfamily
LRO55_RS08090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LRO55_RS08095	COG3485	protocatechuate 3,4-dioxygenase
LRO55_RS08100	COG3485	protocatechuate 3,4-dioxygenase
LRO55_RS08105	COG0710	3-dehydroquinate dehydratase activity
LRO55_RS08110	COG3420	alginic acid biosynthetic process
LRO55_RS08115	COG3659	wide pore channel activity
LRO55_RS08120	COG4993	Dehydrogenase
LRO55_RS08130	COG2391	methyltransferase activity
LRO55_RS08145	COG1414	Transcriptional regulator
LRO55_RS08150	COG0583	DNA-binding transcription factor activity
LRO55_RS08155	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS08180	COG2814	Major facilitator Superfamily
LRO55_RS08190	COG0154	amidase activity
LRO55_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS08230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRO55_RS08240	COG3733	amine oxidase
LRO55_RS08250	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS08260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LRO55_RS08265	COG0183	Belongs to the thiolase family
LRO55_RS08270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LRO55_RS08275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LRO55_RS08285	COG4829	muconolactone delta-isomerase
LRO55_RS08290	COG4948	Mandelate Racemase Muconate Lactonizing
LRO55_RS08295	COG0583	DNA-binding transcription factor activity
LRO55_RS08305	COG2186	Transcriptional regulator
LRO55_RS08325	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS08355	COG1309	transcriptional regulator
LRO55_RS08375	COG0604	alcohol dehydrogenase
LRO55_RS08375	COG3321	synthase
LRO55_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS08405	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS08430	COG1902	pentaerythritol trinitrate reductase activity
LRO55_RS08440	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS08450	COG0300	oxidoreductase activity
LRO55_RS08460	COG1733	regulation of RNA biosynthetic process
LRO55_RS08465	COG0702	epimerase
LRO55_RS08480	COG4689	acetoacetate decarboxylase
LRO55_RS08490	COG1902	pentaerythritol trinitrate reductase activity
LRO55_RS08505	COG1309	transcriptional regulator
LRO55_RS08590	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
LRO55_RS08650	COG2188	Transcriptional regulator
LRO55_RS08690	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LRO55_RS08715	COG2207	Transcriptional regulator
LRO55_RS08720	COG1064	alcohol dehydrogenase
LRO55_RS08730	COG1073	alpha beta
LRO55_RS08735	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRO55_RS08740	COG2207	Transcriptional regulator
LRO55_RS08760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LRO55_RS08765	COG1120	ATPase activity
LRO55_RS08785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LRO55_RS08890	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LRO55_RS08910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS08940	COG2175	clavaminate synthase activity
LRO55_RS08955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS08960	COG0667	Aldo Keto reductase
LRO55_RS08975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LRO55_RS08980	COG2175	clavaminate synthase activity
LRO55_RS09015	COG4628	conserved protein (DUF2132)
LRO55_RS09020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS09055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS09060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRO55_RS09065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS09070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS09085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LRO55_RS09090	COG0805	protein transport
LRO55_RS09100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS09120	COG1132	(ABC) transporter
LRO55_RS09125	COG1132	(ABC) transporter
LRO55_RS09145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LRO55_RS09150	COG0601	transmembrane transport
LRO55_RS09155	COG0747	negative chemotaxis
LRO55_RS09180	COG3539	Fimbrial protein
LRO55_RS09205	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LRO55_RS09215	COG0753	catalase activity
LRO55_RS09235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LRO55_RS09245	COG2205	protein histidine kinase activity
LRO55_RS09250	COG0745	RESPONSE REGULATOR receiver
LRO55_RS09255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS09260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRO55_RS09315	COG4771	TonB-dependent receptor
LRO55_RS09320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRO55_RS09325	COG3433	isochorismatase activity
LRO55_RS09325	COG1535	isochorismatase
LRO55_RS09335	COG1021	2,3-dihydroxybenzoate-AMP ligase
LRO55_RS09340	COG1169	isochorismate synthase
LRO55_RS09345	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS09355	COG3251	PFAM MbtH domain protein
LRO55_RS09360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRO55_RS09385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LRO55_RS09390	COG4149	molybdate abc transporter
LRO55_RS09395	COG0725	ABC transporter, periplasmic molybdate-binding protein
LRO55_RS09405	COG4638	Rieske (2fe-2S)
LRO55_RS09410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LRO55_RS09415	COG0543	2 iron, 2 sulfur cluster binding
LRO55_RS09415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRO55_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS09460	COG2207	Transcriptional regulator
LRO55_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS09470	COG2610	gluconate transmembrane transporter activity
LRO55_RS09545	COG0583	DNA-binding transcription factor activity
LRO55_RS09560	COG2031	fatty acid transporter
LRO55_RS09565	COG0183	Belongs to the thiolase family
LRO55_RS09570	COG0583	DNA-binding transcription factor activity
LRO55_RS09575	COG0583	DNA-binding transcription factor activity
LRO55_RS09590	COG1027	Aspartate ammonia-lyase
LRO55_RS09600	COG0477	Major facilitator Superfamily
LRO55_RS09625	COG4521	taurine ABC transporter
LRO55_RS09640	COG2188	Transcriptional regulator
LRO55_RS09650	COG3708	Transcriptional regulator
LRO55_RS09650	COG2207	Transcriptional regulator
LRO55_RS09680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRO55_RS09680	COG3453	Protein conserved in bacteria
LRO55_RS09700	COG1063	alcohol dehydrogenase
LRO55_RS09710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LRO55_RS09715	COG0508	dehydrogenase complex catalyzes the overall conversion of
LRO55_RS09720	COG0022	dehydrogenase e1 component
LRO55_RS09725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LRO55_RS09730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LRO55_RS09745	COG3706	GGDEF domain
LRO55_RS09765	COG0133	tryptophan synthase activity
LRO55_RS09775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LRO55_RS09805	COG0583	DNA-binding transcription factor activity
LRO55_RS09810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LRO55_RS09820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LRO55_RS09880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LRO55_RS09885	COG4773	Receptor
LRO55_RS09905	COG0730	response to heat
LRO55_RS09910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LRO55_RS09925	COG0406	alpha-ribazole phosphatase activity
LRO55_RS09945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LRO55_RS09950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LRO55_RS09965	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS09970	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS09975	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRO55_RS09980	COG2207	Transcriptional regulator
LRO55_RS09985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LRO55_RS09990	COG0776	regulation of translation
LRO55_RS10015	COG0822	iron-sulfur transferase activity
LRO55_RS10020	COG0316	Belongs to the HesB IscA family
LRO55_RS10050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LRO55_RS10070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LRO55_RS10075	COG0702	epimerase
LRO55_RS10105	COG4172	Belongs to the ABC transporter superfamily
LRO55_RS10115	COG0601	transmembrane transport
LRO55_RS10120	COG0339	signal peptide processing
LRO55_RS10125	COG4166	transmembrane transport
LRO55_RS10140	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LRO55_RS10165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LRO55_RS10170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LRO55_RS10185	COG2431	L-lysine efflux transmembrane transporter activity
LRO55_RS10200	COG0776	regulation of translation
LRO55_RS10265	COG0084	hydrolase, TatD family'
LRO55_RS10285	COG1663	tetraacyldisaccharide 4'-kinase activity
LRO55_RS10290	COG1132	(ABC) transporter
LRO55_RS10300	COG0811	peptide transport
LRO55_RS10305	COG1475	DNA binding
LRO55_RS10310	COG1192	Involved in chromosome partitioning
LRO55_RS10320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LRO55_RS10335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LRO55_RS10340	COG0191	fructose-bisphosphate aldolase activity
LRO55_RS10360	COG0424	maF-like protein
LRO55_RS10365	COG2850	peptidyl-arginine hydroxylation
LRO55_RS10375	COG0640	Transcriptional regulator
LRO55_RS10385	COG3619	membrane
LRO55_RS10390	COG3122	Protein conserved in bacteria
LRO55_RS10395	COG1132	(ABC) transporter
LRO55_RS10415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LRO55_RS10420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LRO55_RS10430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LRO55_RS10430	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LRO55_RS10430	COG0506	proline dehydrogenase activity
LRO55_RS10435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LRO55_RS10450	COG3698	Phosphodiester glycosidase
LRO55_RS10460	COG2353	YceI-like domain
LRO55_RS10470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LRO55_RS10515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LRO55_RS10515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LRO55_RS10540	COG3539	Fimbrial protein
LRO55_RS10545	COG3121	Chaperone
LRO55_RS10575	COG0583	DNA-binding transcription factor activity
LRO55_RS10580	COG0697	spore germination
LRO55_RS10590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LRO55_RS10600	COG0583	DNA-binding transcription factor activity
LRO55_RS10615	COG1309	transcriptional regulator
LRO55_RS10630	COG1522	sequence-specific DNA binding
LRO55_RS10640	COG1126	abc transporter atp-binding protein
LRO55_RS10645	COG0765	amino acid transport
LRO55_RS10650	COG0765	amino acid transport
LRO55_RS10655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LRO55_RS10680	COG1464	Belongs to the NlpA lipoprotein family
LRO55_RS10690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LRO55_RS10695	COG2011	ABC-type metal ion transport system permease component
LRO55_RS10700	COG0012	GTP binding
LRO55_RS10725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LRO55_RS10760	COG1917	Cupin 2, conserved barrel domain protein
LRO55_RS10760	COG2207	Transcriptional regulator
LRO55_RS10765	COG0386	Belongs to the glutathione peroxidase family
LRO55_RS10775	COG0436	Aminotransferase
LRO55_RS10780	COG1301	dicarboxylic acid transport
LRO55_RS10815	COG3634	alkyl hydroperoxide reductase activity
LRO55_RS10830	COG0583	DNA-binding transcription factor activity
LRO55_RS10835	COG0431	NADPH-dependent FMN reductase
LRO55_RS10840	COG0798	PFAM Bile acid sodium symporter
LRO55_RS10850	COG0640	Transcriptional regulator
LRO55_RS10865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LRO55_RS10875	COG0583	DNA-binding transcription factor activity
LRO55_RS10885	COG1953	Uracil, thiamine, allantoin
LRO55_RS10895	COG2175	clavaminate synthase activity
LRO55_RS10900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS10905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LRO55_RS10910	COG4521	taurine ABC transporter
LRO55_RS10920	COG0477	Major facilitator Superfamily
LRO55_RS10940	COG1271	oxidase subunit
LRO55_RS10945	COG1294	oxidase, subunit
LRO55_RS10955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRO55_RS10975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LRO55_RS10995	COG3052	prosthetic group binding
LRO55_RS11000	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LRO55_RS11010	COG2814	Major facilitator Superfamily
LRO55_RS11030	COG1346	cytolysis
LRO55_RS11040	COG0583	DNA-binding transcription factor activity
LRO55_RS11045	COG0625	glutathione transferase activity
LRO55_RS11050	COG0625	glutathione transferase activity
LRO55_RS11075	COG1045	serine acetyltransferase
LRO55_RS11080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LRO55_RS11085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LRO55_RS11095	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS11100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LRO55_RS11115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LRO55_RS11120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LRO55_RS11130	COG0765	amino acid transport
LRO55_RS11135	COG0765	amino acid transport
LRO55_RS11145	COG2388	GCN5-related N-acetyl-transferase
LRO55_RS11195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LRO55_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS11260	COG0583	DNA-binding transcription factor activity
LRO55_RS11270	COG2814	Major facilitator Superfamily
LRO55_RS11285	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS11290	COG1309	transcriptional regulator
LRO55_RS11295	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS11300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LRO55_RS11305	COG1024	Enoyl-CoA hydratase
LRO55_RS11310	COG4770	biotin carboxylase activity
LRO55_RS11320	COG0583	DNA-binding transcription factor activity
LRO55_RS11335	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS11345	COG2814	Major facilitator Superfamily
LRO55_RS11355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LRO55_RS11360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LRO55_RS11365	COG2814	Major facilitator Superfamily
LRO55_RS11370	COG2814	Major facilitator Superfamily
LRO55_RS11375	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS11380	COG1024	Enoyl-CoA hydratase
LRO55_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS11390	COG1250	3-hydroxyacyl-CoA dehydrogenase
LRO55_RS11395	COG0183	Belongs to the thiolase family
LRO55_RS11410	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS11415	COG2192	nodulation
LRO55_RS11430	COG1024	Enoyl-CoA hydratase
LRO55_RS11440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LRO55_RS11445	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS11450	COG2814	Major facilitator Superfamily
LRO55_RS11455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRO55_RS11460	COG1414	Transcriptional regulator
LRO55_RS11510	COG1760	l-serine dehydratase
LRO55_RS11525	COG0789	Transcriptional regulator
LRO55_RS11535	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LRO55_RS11540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRO55_RS11555	COG2807	transmembrane transport
LRO55_RS11560	COG0590	tRNA wobble adenosine to inosine editing
LRO55_RS11615	COG2885	chlorophyll binding
LRO55_RS11715	COG0583	DNA-binding transcription factor activity
LRO55_RS11720	COG0477	Major facilitator Superfamily
LRO55_RS11735	COG1116	anion transmembrane transporter activity
LRO55_RS11740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LRO55_RS11750	COG0864	Transcriptional regulator
LRO55_RS11765	COG1733	regulation of RNA biosynthetic process
LRO55_RS11770	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRO55_RS11775	COG0439	Biotin carboxylase
LRO55_RS11790	COG1250	3-hydroxyacyl-CoA dehydrogenase
LRO55_RS11840	COG0038	chloride channel
LRO55_RS11845	COG4770	biotin carboxylase activity
LRO55_RS11865	COG1914	H( )-stimulated, divalent metal cation uptake system
LRO55_RS11915	COG1309	transcriptional regulator
LRO55_RS11930	COG1309	transcriptional regulator
LRO55_RS11945	COG0657	acetylesterase activity
LRO55_RS11955	COG2259	Doxx family
LRO55_RS11970	COG3712	iron ion homeostasis
LRO55_RS12040	COG4521	taurine ABC transporter
LRO55_RS12045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS12050	COG1116	anion transmembrane transporter activity
LRO55_RS12055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LRO55_RS12070	COG1522	sequence-specific DNA binding
LRO55_RS12125	COG0531	amino acid
LRO55_RS12130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LRO55_RS12145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LRO55_RS12175	COG2050	protein possibly involved in aromatic compounds catabolism
LRO55_RS12185	COG3327	negative regulation of DNA-templated transcription, initiation
LRO55_RS12190	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LRO55_RS12195	COG0183	Belongs to the thiolase family
LRO55_RS12200	COG1250	3-hydroxyacyl-CoA dehydrogenase
LRO55_RS12205	COG1024	Enoyl-CoA hydratase
LRO55_RS12210	COG1024	Enoyl-CoA hydratase
LRO55_RS12215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRO55_RS12220	COG2151	metal-sulfur cluster biosynthetic enzyme
LRO55_RS12225	COG3396	Phenylacetate-CoA oxygenase
LRO55_RS12230	COG3460	Phenylacetate-CoA oxygenase
LRO55_RS12235	COG3396	Phenylacetate-CoA oxygenase
LRO55_RS12240	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS12240	COG2030	dehydratase
LRO55_RS12265	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LRO55_RS12280	COG4122	O-methyltransferase activity
LRO55_RS12310	COG1538	Outer membrane efflux protein
LRO55_RS12320	COG1137	ATPase activity
LRO55_RS12325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LRO55_RS12335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LRO55_RS12385	COG2814	Major facilitator Superfamily
LRO55_RS12415	COG0668	transmembrane transport
LRO55_RS12470	COG2226	methyltransferase
LRO55_RS12495	COG1278	Cold shock
LRO55_RS12500	COG1560	Kdo2-lipid A biosynthetic process
LRO55_RS12505	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS12540	COG1570	exodeoxyribonuclease VII activity
LRO55_RS12590	COG0583	DNA-binding transcription factor activity
LRO55_RS12600	COG4638	Rieske (2fe-2S)
LRO55_RS12610	COG0543	2 iron, 2 sulfur cluster binding
LRO55_RS12610	COG0633	Ferredoxin
LRO55_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS12620	COG3135	benzoate transporter
LRO55_RS12625	COG2814	Major facilitator Superfamily
LRO55_RS12640	COG1643	Atp-dependent helicase
LRO55_RS12645	COG0450	alkyl hydroperoxide reductase
LRO55_RS12655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRO55_RS12675	COG3634	alkyl hydroperoxide reductase activity
LRO55_RS12695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LRO55_RS12705	COG0625	glutathione transferase activity
LRO55_RS12715	COG2885	chlorophyll binding
LRO55_RS12750	COG0542	response to heat
LRO55_RS12765	COG1765	OsmC-like protein
LRO55_RS12780	COG0667	Aldo Keto reductase
LRO55_RS12795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LRO55_RS12810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LRO55_RS12820	COG0527	aspartate kinase activity
LRO55_RS12830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LRO55_RS12840	COG3038	cytochrome b561
LRO55_RS12845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LRO55_RS12850	COG2252	PERMEase
LRO55_RS12860	COG1741	Belongs to the pirin family
LRO55_RS12865	COG1309	transcriptional regulator
LRO55_RS12875	COG0300	oxidoreductase activity
LRO55_RS12880	COG2072	flavoprotein involved in K transport
LRO55_RS12885	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LRO55_RS12915	COG1944	ATP diphosphatase activity
LRO55_RS12935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LRO55_RS12950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRO55_RS12965	COG2814	Major facilitator Superfamily
LRO55_RS12970	COG1024	Enoyl-CoA hydratase
LRO55_RS12975	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS12985	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS13010	COG2186	Transcriptional regulator
LRO55_RS13015	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS13025	COG4948	Mandelate Racemase Muconate Lactonizing
LRO55_RS13030	COG2271	Major facilitator Superfamily
LRO55_RS13035	COG2721	sulfolactate sulfo-lyase activity
LRO55_RS13040	COG0697	spore germination
LRO55_RS13090	COG1113	amino acid transport
LRO55_RS13110	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS13130	COG0531	amino acid
LRO55_RS13140	COG1113	amino acid transport
LRO55_RS13170	COG1309	transcriptional regulator
LRO55_RS13180	COG4269	membrane
LRO55_RS13240	COG1902	pentaerythritol trinitrate reductase activity
LRO55_RS13240	COG0446	pyridine nucleotide-disulphide oxidoreductase
LRO55_RS13255	COG2203	Gaf domain
LRO55_RS13255	COG5001	Diguanylate cyclase
LRO55_RS13255	COG4251	negative regulation of phosphorylation
LRO55_RS13255	COG3706	GGDEF domain
LRO55_RS13265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LRO55_RS13300	COG4172	Belongs to the ABC transporter superfamily
LRO55_RS13305	COG4239	(ABC) transporter, permease
LRO55_RS13310	COG4174	ABC transporter (Permease)
LRO55_RS13320	COG1388	LysM domain
LRO55_RS13320	COG0741	lytic transglycosylase activity
LRO55_RS13320	COG1388	LysM domain
LRO55_RS13320	COG0741	lytic transglycosylase activity
LRO55_RS13365	COG0583	DNA-binding transcription factor activity
LRO55_RS13380	COG0789	Transcriptional regulator
LRO55_RS13390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRO55_RS13395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRO55_RS13400	COG0006	proline dipeptidase activity
LRO55_RS13440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LRO55_RS13455	COG3384	dioxygenase
LRO55_RS13465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LRO55_RS13470	COG2878	Part of a membrane complex involved in electron transport
LRO55_RS13475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LRO55_RS13500	COG0768	penicillin binding
LRO55_RS13505	COG0742	ribosomal rna small subunit methyltransferase
LRO55_RS13520	COG0830	nickel cation binding
LRO55_RS13530	COG0804	urea catabolic process
LRO55_RS13555	COG3015	lipoprotein NlpE involved in copper resistance
LRO55_RS13570	COG1253	flavin adenine dinucleotide binding
LRO55_RS13575	COG2851	Citrate transporter
LRO55_RS13625	COG1773	rubredoxin
LRO55_RS13630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRO55_RS13640	COG0583	DNA-binding transcription factor activity
LRO55_RS13670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LRO55_RS13675	COG4181	ATPase activity
LRO55_RS13720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LRO55_RS13740	COG0306	phosphate transporter
LRO55_RS13760	COG3958	Transketolase
LRO55_RS13765	COG3959	Transketolase, thiamine diphosphate binding domain
LRO55_RS13770	COG2271	Major facilitator Superfamily
LRO55_RS13775	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS13780	COG0583	DNA-binding transcription factor activity
LRO55_RS13795	COG2223	nitrite transmembrane transporter activity
LRO55_RS13805	COG2066	Belongs to the glutaminase family
LRO55_RS13810	COG0242	peptide deformylase activity
LRO55_RS13815	COG0477	Major facilitator Superfamily
LRO55_RS13825	COG0028	Belongs to the TPP enzyme family
LRO55_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS13845	COG2267	carboxylic ester hydrolase activity
LRO55_RS13855	COG2271	Major facilitator Superfamily
LRO55_RS13870	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS13890	COG1414	Transcriptional regulator
LRO55_RS13910	COG1024	Enoyl-CoA hydratase
LRO55_RS13920	COG1309	transcriptional regulator
LRO55_RS13930	COG1215	transferase activity, transferring glycosyl groups
LRO55_RS13935	COG0726	polysaccharide deacetylase
LRO55_RS13935	COG1649	PFAM Uncharacterised BCR, COG1649
LRO55_RS13945	COG4681	YaeQ
LRO55_RS13955	COG0523	cobalamin synthesis protein
LRO55_RS13965	COG1607	acyl-coa hydrolase
LRO55_RS13975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LRO55_RS13980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LRO55_RS13985	COG1309	transcriptional regulator
LRO55_RS14010	COG2040	homocysteine
LRO55_RS14015	COG0531	amino acid
LRO55_RS14040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS14060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRO55_RS14065	COG0477	Major facilitator Superfamily
LRO55_RS14135	COG0405	Gamma-glutamyltransferase
LRO55_RS14140	COG2814	Major facilitator Superfamily
LRO55_RS14145	COG1566	PFAM secretion protein HlyD family protein
LRO55_RS14150	COG2050	protein possibly involved in aromatic compounds catabolism
LRO55_RS14165	COG1090	epimerase
LRO55_RS14185	COG0420	3'-5' exonuclease activity
LRO55_RS14210	COG0735	belongs to the Fur family
LRO55_RS14215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LRO55_RS14220	COG2914	Belongs to the UPF0125 (RnfH) family
LRO55_RS14235	COG0121	glutamine amidotransferase
LRO55_RS14250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LRO55_RS14260	COG0210	DNA helicase
LRO55_RS14265	COG2885	chlorophyll binding
LRO55_RS14270	COG0204	Acyl-transferase
LRO55_RS14305	COG1280	lysine exporter protein (LysE YggA)
LRO55_RS14310	COG1674	ftsk spoiiie
LRO55_RS14315	COG0492	ferredoxin-NADP+ reductase activity
LRO55_RS14325	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LRO55_RS14335	COG0456	acetyltransferase
LRO55_RS14350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LRO55_RS14355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LRO55_RS14360	COG0049	tRNA binding
LRO55_RS14365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LRO55_RS14380	COG1981	membrane
LRO55_RS14390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LRO55_RS14390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LRO55_RS14420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LRO55_RS14460	COG0358	DNA primase activity
LRO55_RS14475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LRO55_RS14505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LRO55_RS14535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LRO55_RS14545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LRO55_RS14545	COG0351	phosphomethylpyrimidine kinase
LRO55_RS14545	COG0352	thiamine-phosphate diphosphorylase activity
LRO55_RS14550	COG1652	LysM domain
LRO55_RS14560	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS14575	COG1399	metal-binding, possibly nucleic acid-binding protein
LRO55_RS14580	COG3101	peptidyl-lysine hydroxylation
LRO55_RS14585	COG0009	L-threonylcarbamoyladenylate synthase
LRO55_RS14590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LRO55_RS14595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LRO55_RS14610	COG4106	trans-aconitate 2-methyltransferase activity
LRO55_RS14625	COG2226	methyltransferase
LRO55_RS14625	COG0596	Alpha beta hydrolase
LRO55_RS14625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LRO55_RS14635	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LRO55_RS14640	COG2223	nitrite transmembrane transporter activity
LRO55_RS14660	COG1196	nuclear chromosome segregation
LRO55_RS14670	COG0730	response to heat
LRO55_RS14685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LRO55_RS14740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LRO55_RS14745	COG0489	protein tyrosine kinase activity
LRO55_RS14760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LRO55_RS14760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LRO55_RS14795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LRO55_RS14800	COG2081	HI0933 family
LRO55_RS14810	COG0668	transmembrane transport
LRO55_RS14825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRO55_RS14830	COG0583	DNA-binding transcription factor activity
LRO55_RS14855	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LRO55_RS14860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LRO55_RS14875	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LRO55_RS14890	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LRO55_RS14915	COG2199	diguanylate cyclase activity
LRO55_RS14930	COG0745	RESPONSE REGULATOR receiver
LRO55_RS14950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LRO55_RS14955	COG3781	membrane
LRO55_RS14960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LRO55_RS14985	COG0303	'Molybdopterin
LRO55_RS14990	COG0521	Mo-molybdopterin cofactor biosynthetic process
LRO55_RS14990	COG0315	cyclic pyranopterin monophosphate synthase activity
LRO55_RS14995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LRO55_RS15005	COG1294	oxidase, subunit
LRO55_RS15010	COG1271	oxidase subunit
LRO55_RS15020	COG0583	DNA-binding transcription factor activity
LRO55_RS15025	COG0251	oxidation-reduction process
LRO55_RS15040	COG0583	DNA-binding transcription factor activity
LRO55_RS15045	COG3403	YqcI/YcgG family
LRO55_RS15065	COG1309	transcriptional regulator
LRO55_RS15085	COG0546	phosphoglycolate phosphatase activity
LRO55_RS15090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRO55_RS15095	COG1309	transcriptional regulator
LRO55_RS15100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRO55_RS15115	COG0583	DNA-binding transcription factor activity
LRO55_RS15145	COG0583	DNA-binding transcription factor activity
LRO55_RS15160	COG0583	DNA-binding transcription factor activity
LRO55_RS15165	COG1053	succinate dehydrogenase
LRO55_RS15180	COG1309	transcriptional regulator
LRO55_RS15190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LRO55_RS15195	COG2814	Major facilitator Superfamily
LRO55_RS15200	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS15205	COG0583	DNA-binding transcription factor activity
LRO55_RS15210	COG1063	alcohol dehydrogenase
LRO55_RS15240	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LRO55_RS15245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LRO55_RS15265	COG3667	copper resistance
LRO55_RS15270	COG2132	Multicopper oxidase
LRO55_RS15280	COG0561	phosphatase activity
LRO55_RS15285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LRO55_RS15310	COG1214	PFAM Peptidase M22, glycoprotease
LRO55_RS15320	COG0494	nUDIX hydrolase
LRO55_RS15355	COG1134	teichoic acid transport
LRO55_RS15355	COG1388	LysM domain
LRO55_RS15370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LRO55_RS15375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LRO55_RS15380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LRO55_RS15440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LRO55_RS15450	COG1846	Transcriptional regulator
LRO55_RS15455	COG1764	response to oxidative stress
LRO55_RS15480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LRO55_RS15480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LRO55_RS15495	COG0037	tRNA processing
LRO55_RS15505	COG0248	Ppx GppA phosphatase
LRO55_RS15535	COG0072	phenylalanine-tRNA ligase activity
LRO55_RS15565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LRO55_RS15575	COG1238	metal cluster binding
LRO55_RS15580	COG0625	glutathione transferase activity
LRO55_RS15585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LRO55_RS15595	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS15600	COG3028	Belongs to the UPF0307 family
LRO55_RS15605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LRO55_RS15625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LRO55_RS15630	COG0617	tRNA 3'-terminal CCA addition
LRO55_RS15635	COG1555	photosystem II stabilization
LRO55_RS15640	COG3956	TIGRFAM MazG family protein
LRO55_RS15650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LRO55_RS15665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LRO55_RS15670	COG5002	protein histidine kinase activity
LRO55_RS15670	COG0784	Response regulator, receiver
LRO55_RS15670	COG2205	protein histidine kinase activity
LRO55_RS15675	COG1024	Enoyl-CoA hydratase
LRO55_RS15680	COG2084	Dehydrogenase
LRO55_RS15685	COG3622	Belongs to the hyi family
LRO55_RS15715	COG0697	spore germination
LRO55_RS15725	COG2814	Major facilitator Superfamily
LRO55_RS15730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LRO55_RS15745	COG0583	DNA-binding transcription factor activity
LRO55_RS15755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LRO55_RS15765	COG0084	hydrolase, TatD family'
LRO55_RS15780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LRO55_RS15805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LRO55_RS15810	COG0440	acetolactate synthase activity
LRO55_RS15815	COG0028	Belongs to the TPP enzyme family
LRO55_RS15835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRO55_RS15840	COG1136	(ABC) transporter
LRO55_RS15840	COG0577	efflux transmembrane transporter activity
LRO55_RS15870	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LRO55_RS15875	COG1162	GTPase activity
LRO55_RS15885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LRO55_RS15905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LRO55_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS15950	COG2986	histidine ammonia-lyase
LRO55_RS15965	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS15975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LRO55_RS16000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LRO55_RS16020	COG1426	Protein conserved in bacteria
LRO55_RS16040	COG2975	iron-sulfur cluster assembly
LRO55_RS16055	COG0793	Belongs to the peptidase S41A family
LRO55_RS16070	COG2267	carboxylic ester hydrolase activity
LRO55_RS16080	COG1012	belongs to the aldehyde dehydrogenase family
LRO55_RS16085	COG3265	gluconokinase activity
LRO55_RS16095	COG0800	Aldolase
LRO55_RS16110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LRO55_RS16115	COG0280	phosphate acetyltransferase
LRO55_RS16115	COG0857	belongs to the CobB CobQ family
LRO55_RS16120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LRO55_RS16120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LRO55_RS16140	COG0740	serine-type endopeptidase activity
LRO55_RS16150	COG4774	siderophore transport
LRO55_RS16160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LRO55_RS16170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LRO55_RS16170	COG2813	Specifically methylates the guanine in position
LRO55_RS16270	COG0788	formyltetrahydrofolate deformylase activity
LRO55_RS16295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LRO55_RS16295	COG4651	solute:proton antiporter activity
LRO55_RS16315	COG0724	RNA recognition motif
LRO55_RS16320	COG0210	DNA helicase
LRO55_RS16345	COG1733	regulation of RNA biosynthetic process
LRO55_RS16350	COG0604	alcohol dehydrogenase
LRO55_RS16355	COG2900	Belongs to the SlyX family
LRO55_RS16360	COG0488	(ABC) transporter
LRO55_RS16370	COG1560	Kdo2-lipid A biosynthetic process
LRO55_RS16380	COG1301	dicarboxylic acid transport
LRO55_RS16435	COG0473	3-isopropylmalate dehydrogenase activity
LRO55_RS16460	COG0583	DNA-binding transcription factor activity
LRO55_RS16505	COG0583	DNA-binding transcription factor activity
LRO55_RS16515	COG0625	glutathione transferase activity
LRO55_RS16520	COG2378	regulation of single-species biofilm formation
LRO55_RS16535	COG1530	ribonuclease E activity
LRO55_RS16540	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS16555	COG0583	DNA-binding transcription factor activity
LRO55_RS16560	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS16565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LRO55_RS16575	COG0534	Mate efflux family protein
LRO55_RS16590	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LRO55_RS16615	COG0493	'glutamate synthase
LRO55_RS16625	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LRO55_RS16630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRO55_RS16645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LRO55_RS16655	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LRO55_RS16655	COG0644	oxidoreductase
LRO55_RS16670	COG4535	Mg2 and Co2 transporter CorC
LRO55_RS16675	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LRO55_RS16680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LRO55_RS16705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LRO55_RS16715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LRO55_RS16725	COG0484	heat shock protein binding
LRO55_RS16730	COG0789	Transcriptional regulator
LRO55_RS16735	COG0598	Magnesium transport protein CorA
LRO55_RS16740	COG1185	polyribonucleotide nucleotidyltransferase activity
LRO55_RS16750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LRO55_RS16755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LRO55_RS16760	COG1074	ATP-dependent DNA helicase activity
LRO55_RS16765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LRO55_RS16785	COG2226	methyltransferase
LRO55_RS16810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LRO55_RS16825	COG2111	Na H antiporter
LRO55_RS16825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LRO55_RS16830	COG1006	Multisubunit Na H antiporter MnhC subunit
LRO55_RS16835	COG0651	ATP synthesis coupled electron transport
LRO55_RS16840	COG1863	multisubunit Na H antiporter MnhE subunit
LRO55_RS16845	COG2212	antiporter activity
LRO55_RS16850	COG1320	monovalent cation:proton antiporter activity
LRO55_RS16855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LRO55_RS16865	COG0195	Participates in both transcription termination and antitermination
LRO55_RS16920	COG0237	dephospho-CoA kinase activity
LRO55_RS16930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LRO55_RS16945	COG0497	DNA recombination
LRO55_RS16955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LRO55_RS16990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LRO55_RS16990	COG2169	Transcriptional regulator
LRO55_RS17000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LRO55_RS17070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LRO55_RS17085	COG0326	Molecular chaperone. Has ATPase activity
LRO55_RS17100	COG2056	Na+-H+ antiporter family
LRO55_RS17135	COG0222	ribosome binding
LRO55_RS17140	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LRO55_RS17170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LRO55_RS17200	COG0546	phosphoglycolate phosphatase activity
LRO55_RS17205	COG1716	ATPase activity
LRO55_RS17250	COG0181	hydroxymethylbilane synthase activity
LRO55_RS17260	COG3275	phosphorelay sensor kinase activity
LRO55_RS17280	COG1538	Outer membrane efflux protein
LRO55_RS17315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LRO55_RS17320	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LRO55_RS17325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LRO55_RS17330	COG0772	Belongs to the SEDS family
LRO55_RS17355	COG4974	Belongs to the 'phage' integrase family
LRO55_RS17360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LRO55_RS17370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LRO55_RS17380	COG2197	response regulator
LRO55_RS17395	COG0793	Belongs to the peptidase S41A family
LRO55_RS17400	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LRO55_RS17405	COG0795	lipopolysaccharide-transporting ATPase activity
LRO55_RS17445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LRO55_RS17445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LRO55_RS17455	COG0004	ammonium transporteR
LRO55_RS17460	COG0347	Belongs to the P(II) protein family
LRO55_RS17480	COG0494	nUDIX hydrolase
LRO55_RS17495	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LRO55_RS17535	COG0431	NADPH-dependent FMN reductase
LRO55_RS17545	COG0235	Class ii aldolase
LRO55_RS17550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRO55_RS17570	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LRO55_RS17585	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS17595	COG0477	Major facilitator Superfamily
LRO55_RS17600	COG2860	membrane
LRO55_RS17605	COG3012	SEC-C Motif Domain Protein
LRO55_RS17610	COG1253	flavin adenine dinucleotide binding
LRO55_RS17620	COG2814	Major facilitator Superfamily
LRO55_RS17630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LRO55_RS17655	COG0789	Transcriptional regulator
LRO55_RS17665	COG0655	NAD(P)H dehydrogenase (quinone) activity
LRO55_RS17680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LRO55_RS17750	COG0758	DNA mediated transformation
LRO55_RS17760	COG0697	spore germination
LRO55_RS17765	COG1309	transcriptional regulator
LRO55_RS17780	COG0386	Belongs to the glutathione peroxidase family
LRO55_RS17790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LRO55_RS17795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LRO55_RS17800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LRO55_RS17845	COG1121	(ABC) transporter
LRO55_RS17850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LRO55_RS17860	COG2837	iron assimilation
LRO55_RS17865	COG0281	malic enzyme
LRO55_RS17915	COG2084	Dehydrogenase
LRO55_RS17920	COG0519	Catalyzes the synthesis of GMP from XMP
LRO55_RS17920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LRO55_RS17925	COG4399	Belongs to the UPF0754 family
LRO55_RS17930	COG2259	Doxx family
LRO55_RS17935	COG0586	Pfam SNARE associated Golgi protein
LRO55_RS17950	COG1192	Involved in chromosome partitioning
LRO55_RS17960	COG0271	Belongs to the BolA IbaG family
LRO55_RS17995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRO55_RS18000	COG3321	synthase
LRO55_RS18000	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS18000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRO55_RS18000	COG0318	PFAM AMP-dependent synthetase and ligase
LRO55_RS18000	COG0300	oxidoreductase activity
LRO55_RS18005	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS18015	COG2197	response regulator
LRO55_RS18025	COG3916	Acyl-homoserine-lactone synthase
LRO55_RS18030	COG0477	Major facilitator Superfamily
LRO55_RS18035	COG1024	Enoyl-CoA hydratase
LRO55_RS18040	COG1024	Enoyl-CoA hydratase
LRO55_RS18045	COG1960	acyl-CoA dehydrogenase activity
LRO55_RS18050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LRO55_RS18070	COG1113	amino acid transport
LRO55_RS18075	COG1113	amino acid transport
LRO55_RS18080	COG0251	oxidation-reduction process
LRO55_RS18120	COG0564	pseudouridine synthase activity
LRO55_RS18225	COG1802	Transcriptional regulator
LRO55_RS18245	COG2186	Transcriptional regulator
LRO55_RS18260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LRO55_RS18275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LRO55_RS18285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LRO55_RS18295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LRO55_RS18350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LRO55_RS18355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LRO55_RS18360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LRO55_RS18390	COG0728	peptidoglycan biosynthetic process
LRO55_RS18395	COG3023	N-Acetylmuramoyl-L-alanine amidase
LRO55_RS18450	COG0546	phosphoglycolate phosphatase activity
LRO55_RS18455	COG1028	Short-chain dehydrogenase reductase Sdr
LRO55_RS18470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LRO55_RS18470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LRO55_RS18475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRO55_RS18480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRO55_RS18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRO55_RS18490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRO55_RS18495	COG1116	anion transmembrane transporter activity
LRO55_RS18500	COG1309	transcriptional regulator
LRO55_RS18505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LRO55_RS18515	COG0196	riboflavin kinase activity
LRO55_RS18520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LRO55_RS18530	COG1047	Peptidyl-prolyl cis-trans
LRO55_RS18570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LRO55_RS18575	COG0657	acetylesterase activity
LRO55_RS18595	COG0583	DNA-binding transcription factor activity
LRO55_RS18630	COG2951	lytic endotransglycosylase activity
LRO55_RS18635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LRO55_RS18650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LRO55_RS18660	COG0671	phosphoesterase, PA-phosphatase related
LRO55_RS18665	COG0861	Integral membrane protein TerC family
LRO55_RS18675	COG0754	glutathionylspermidine amidase activity
LRO55_RS18685	COG0402	S-adenosylhomocysteine deaminase activity
LRO55_RS18705	COG1230	cation diffusion facilitator family transporter
LRO55_RS18720	COG0706	membrane insertase activity