locus-tag	class	description
AC2117_RS00015	COG0592	DNA-directed DNA polymerase activity
AC2117_RS00025	COG0187	DNA topoisomerase II activity
AC2117_RS00040	COG0488	(ABC) transporter
AC2117_RS00065	COG0596	Alpha beta hydrolase
AC2117_RS00070	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AC2117_RS00075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AC2117_RS00120	COG0733	neurotransmitter:sodium symporter activity
AC2117_RS00160	COG2233	PERMEase
AC2117_RS00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC2117_RS00210	COG2814	Major facilitator Superfamily
AC2117_RS00215	COG0656	L-ascorbic acid biosynthetic process
AC2117_RS00220	COG0583	DNA-binding transcription factor activity
AC2117_RS00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC2117_RS00240	COG1064	alcohol dehydrogenase
AC2117_RS00245	COG2818	Glycosylase
AC2117_RS00260	COG1194	a g-specific adenine glycosylase
AC2117_RS00275	COG5487	UPF0391 membrane protein
AC2117_RS00280	COG2983	Belongs to the UPF0260 family
AC2117_RS00285	COG2133	pyrroloquinoline quinone binding
AC2117_RS00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC2117_RS00295	COG2116	formate transmembrane transporter activity
AC2117_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC2117_RS00315	COG1335	isochorismatase
AC2117_RS00320	COG0385	Bile acid
AC2117_RS00325	COG1683	Conserved Protein
AC2117_RS00340	COG0346	lactoylglutathione lyase activity
AC2117_RS00345	COG0625	glutathione transferase activity
AC2117_RS00355	COG1113	amino acid transport
AC2117_RS00365	COG0523	cobalamin synthesis protein
AC2117_RS00370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AC2117_RS00370	COG2755	lipolytic protein G-D-S-L family
AC2117_RS00375	COG2188	Transcriptional regulator
AC2117_RS00405	COG0010	Belongs to the arginase family
AC2117_RS00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AC2117_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC2117_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AC2117_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AC2117_RS00550	COG0534	Mate efflux family protein
AC2117_RS00555	COG0436	Aminotransferase
AC2117_RS00560	COG2733	membrane
AC2117_RS00575	COG2918	glutathione biosynthetic process
AC2117_RS00610	COG3150	esterase
AC2117_RS00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AC2117_RS00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC2117_RS00640	COG2233	PERMEase
AC2117_RS00645	COG2351	hydroxyisourate hydrolase activity
AC2117_RS00680	COG3706	GGDEF domain
AC2117_RS00695	COG1393	Belongs to the ArsC family
AC2117_RS00700	COG0708	Exodeoxyribonuclease III
AC2117_RS00735	COG0189	ligase activity
AC2117_RS00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AC2117_RS00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AC2117_RS00785	COG4942	peptidase
AC2117_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC2117_RS00805	COG2119	membrane
AC2117_RS00810	COG4774	siderophore transport
AC2117_RS00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AC2117_RS00860	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS00865	COG1519	Transferase
AC2117_RS00870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC2117_RS00875	COG0668	transmembrane transport
AC2117_RS00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC2117_RS00890	COG1335	isochorismatase
AC2117_RS00895	COG1522	sequence-specific DNA binding
AC2117_RS00920	COG2205	protein histidine kinase activity
AC2117_RS00920	COG2198	Histidine kinase
AC2117_RS00920	COG0784	Response regulator, receiver
AC2117_RS00925	COG3162	membrane
AC2117_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AC2117_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC2117_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AC2117_RS00960	COG1309	transcriptional regulator
AC2117_RS00985	COG0789	Transcriptional regulator
AC2117_RS00990	COG0351	phosphomethylpyrimidine kinase
AC2117_RS00990	COG0352	thiamine-phosphate diphosphorylase activity
AC2117_RS00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AC2117_RS01000	COG2814	Major facilitator Superfamily
AC2117_RS01005	COG0629	single-stranded DNA binding
AC2117_RS01055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AC2117_RS01065	COG1113	amino acid transport
AC2117_RS01075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AC2117_RS01080	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS01085	COG1335	isochorismatase
AC2117_RS01100	COG1335	isochorismatase
AC2117_RS01175	COG2814	Major facilitator Superfamily
AC2117_RS01180	COG0583	DNA-binding transcription factor activity
AC2117_RS01220	COG0667	Aldo Keto reductase
AC2117_RS01250	COG1733	regulation of RNA biosynthetic process
AC2117_RS01255	COG2249	NAD(P)H dehydrogenase (quinone) activity
AC2117_RS01320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AC2117_RS01345	COG1132	(ABC) transporter
AC2117_RS01365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AC2117_RS01395	COG0427	acetyl-CoA hydrolase
AC2117_RS01420	COG0659	secondary active sulfate transmembrane transporter activity
AC2117_RS01425	COG4221	oxidoreductase activity
AC2117_RS01430	COG2873	o-acetylhomoserine
AC2117_RS01435	COG0488	(ABC) transporter
AC2117_RS01495	COG0833	amino acid
AC2117_RS01540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC2117_RS01545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AC2117_RS01560	COG2226	methyltransferase
AC2117_RS01610	COG0070	glutamate synthase
AC2117_RS01610	COG0067	glutamate synthase
AC2117_RS01610	COG0069	glutamate synthase activity
AC2117_RS01615	COG0493	'glutamate synthase
AC2117_RS01625	COG1704	LemA family
AC2117_RS01630	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AC2117_RS01645	COG3307	-O-antigen
AC2117_RS01665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC2117_RS01680	COG0194	GDP metabolic process
AC2117_RS01730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AC2117_RS01750	COG5380	lipid catabolic process
AC2117_RS01755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AC2117_RS01770	COG5006	permease, DMT superfamily
AC2117_RS01775	COG5006	permease, DMT superfamily
AC2117_RS01780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC2117_RS01785	COG0277	FAD linked oxidase domain protein
AC2117_RS01800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AC2117_RS01825	COG1289	transmembrane transporter activity
AC2117_RS01835	COG0628	permease
AC2117_RS01840	COG1192	Involved in chromosome partitioning
AC2117_RS01870	COG0833	amino acid
AC2117_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AC2117_RS01880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC2117_RS01890	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS01930	COG0583	DNA-binding transcription factor activity
AC2117_RS01935	COG1794	racemase activity, acting on amino acids and derivatives
AC2117_RS01940	COG0583	DNA-binding transcription factor activity
AC2117_RS01965	COG0752	glycyl-tRNA synthetase alpha subunit
AC2117_RS01985	COG0517	IMP dehydrogenase activity
AC2117_RS01990	COG1983	PspC domain protein
AC2117_RS02000	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS02015	COG0408	coproporphyrinogen oxidase activity
AC2117_RS02035	COG0513	Belongs to the DEAD box helicase family
AC2117_RS02045	COG1127	ABC transporter
AC2117_RS02050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC2117_RS02070	COG0598	Magnesium transport protein CorA
AC2117_RS02080	COG0494	nUDIX hydrolase
AC2117_RS02085	COG1040	competence protein
AC2117_RS02090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AC2117_RS02105	COG2937	Belongs to the GPAT DAPAT family
AC2117_RS02110	COG1946	Acyl-CoA thioesterase
AC2117_RS02115	COG1301	dicarboxylic acid transport
AC2117_RS02130	COG1959	2 iron, 2 sulfur cluster binding
AC2117_RS02135	COG1017	nitric oxide dioxygenase activity
AC2117_RS02135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC2117_RS02140	COG0433	COG0433 Predicted ATPase
AC2117_RS02145	COG0626	cystathionine gamma-synthase activity
AC2117_RS02160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AC2117_RS02165	COG0088	Forms part of the polypeptide exit tunnel
AC2117_RS02185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AC2117_RS02300	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS02305	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AC2117_RS02335	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AC2117_RS02340	COG0339	signal peptide processing
AC2117_RS02345	COG0557	exoribonuclease II activity
AC2117_RS02390	COG0179	Fumarylacetoacetate (FAA) hydrolase
AC2117_RS02395	COG1295	ribonuclease BN
AC2117_RS02430	COG1702	phosphate starvation-inducible protein PhoH
AC2117_RS02440	COG0739	heme binding
AC2117_RS02440	COG0741	lytic transglycosylase activity
AC2117_RS02440	COG1196	nuclear chromosome segregation
AC2117_RS02470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AC2117_RS02475	COG1183	phosphatidylcholine synthase activity
AC2117_RS02525	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS02530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC2117_RS02550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AC2117_RS02555	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS02575	COG2969	positive regulation of protein catabolic process
AC2117_RS02580	COG0625	glutathione transferase activity
AC2117_RS02585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AC2117_RS02590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AC2117_RS02600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AC2117_RS02605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AC2117_RS02615	COG1346	cytolysis
AC2117_RS02625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AC2117_RS02635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC2117_RS02640	COG1408	metallophosphoesterase
AC2117_RS02650	COG2199	diguanylate cyclase activity
AC2117_RS02695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC2117_RS02720	COG1607	acyl-coa hydrolase
AC2117_RS02750	COG2350	Protein conserved in bacteria
AC2117_RS02760	COG0613	PHP domain protein
AC2117_RS02765	COG3781	membrane
AC2117_RS02775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AC2117_RS02790	COG1862	Preprotein translocase
AC2117_RS02815	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AC2117_RS02835	COG0726	polysaccharide deacetylase
AC2117_RS02840	COG0463	Glycosyl transferase, family 2
AC2117_RS02845	COG0438	transferase activity, transferring glycosyl groups
AC2117_RS02870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AC2117_RS02910	COG0625	glutathione transferase activity
AC2117_RS02915	COG0583	DNA-binding transcription factor activity
AC2117_RS02920	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS02925	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS02935	COG2205	protein histidine kinase activity
AC2117_RS02940	COG0745	RESPONSE REGULATOR receiver
AC2117_RS02950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AC2117_RS02970	COG2096	Adenosyltransferase
AC2117_RS02975	COG4206	TonB-dependent receptor
AC2117_RS03020	COG0285	dihydrofolate synthase activity
AC2117_RS03045	COG0450	alkyl hydroperoxide reductase
AC2117_RS03060	COG0477	Major facilitator Superfamily
AC2117_RS03065	COG1272	protein, Hemolysin III
AC2117_RS03075	COG2153	protein acetylation
AC2117_RS03095	COG0183	Belongs to the thiolase family
AC2117_RS03100	COG2207	Transcriptional regulator
AC2117_RS03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC2117_RS03135	COG0183	Belongs to the thiolase family
AC2117_RS03145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AC2117_RS03145	COG2885	chlorophyll binding
AC2117_RS03150	COG1690	Belongs to the RtcB family
AC2117_RS03155	COG0833	amino acid
AC2117_RS03165	COG2233	PERMEase
AC2117_RS03170	COG1217	gtp-binding protein TYPA
AC2117_RS03185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC2117_RS03195	COG2094	Belongs to the DNA glycosylase MPG family
AC2117_RS03200	COG4772	TonB-dependent receptor
AC2117_RS03205	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS03210	COG0679	Auxin Efflux Carrier
AC2117_RS03220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC2117_RS03225	COG0354	folic acid binding
AC2117_RS03245	COG2233	PERMEase
AC2117_RS03250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC2117_RS03255	COG0251	oxidation-reduction process
AC2117_RS03260	COG1335	isochorismatase
AC2117_RS03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC2117_RS03270	COG0778	Nitroreductase
AC2117_RS03275	COG0596	Alpha beta hydrolase
AC2117_RS03280	COG3189	MarR family transcriptional regulator
AC2117_RS03285	COG2824	Alkylphosphonate utilization operon protein PhnA
AC2117_RS03290	COG3422	double-strand break repair
AC2117_RS03330	COG0840	transmembrane signaling receptor activity
AC2117_RS03360	COG2832	Protein of unknown function (DUF454)
AC2117_RS03405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AC2117_RS03415	COG1289	transmembrane transporter activity
AC2117_RS03420	COG2814	Major facilitator Superfamily
AC2117_RS03445	COG1115	amino acid carrier protein
AC2117_RS03450	COG1752	Esterase of the alpha-beta hydrolase superfamily
AC2117_RS03455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AC2117_RS03460	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AC2117_RS03495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AC2117_RS03505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AC2117_RS03510	COG1077	Cell shape determining protein MreB Mrl
AC2117_RS03515	COG1792	Involved in formation and maintenance of cell shape
AC2117_RS03520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AC2117_RS03525	COG0424	maF-like protein
AC2117_RS03530	COG1530	ribonuclease E activity
AC2117_RS03540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC2117_RS03560	COG2249	NAD(P)H dehydrogenase (quinone) activity
AC2117_RS03640	COG1113	amino acid transport
AC2117_RS03650	COG0142	geranyltranstransferase activity
AC2117_RS03655	COG2315	Protein conserved in bacteria
AC2117_RS03670	COG1752	Esterase of the alpha-beta hydrolase superfamily
AC2117_RS03695	COG2194	sulfuric ester hydrolase activity
AC2117_RS03700	COG0745	RESPONSE REGULATOR receiver
AC2117_RS03705	COG0642	Histidine kinase
AC2117_RS03715	COG0004	ammonium transporteR
AC2117_RS03720	COG0583	DNA-binding transcription factor activity
AC2117_RS03740	COG0525	valine-tRNA ligase activity
AC2117_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS03760	COG0393	Putative heavy-metal-binding
AC2117_RS03765	COG0393	Putative heavy-metal-binding
AC2117_RS03770	COG1538	Outer membrane efflux protein
AC2117_RS03780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC2117_RS03785	COG0671	phosphoesterase, PA-phosphatase related
AC2117_RS03810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AC2117_RS03825	COG1648	precorrin-2 dehydrogenase activity
AC2117_RS03825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AC2117_RS03830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AC2117_RS03855	COG1733	regulation of RNA biosynthetic process
AC2117_RS03865	COG0531	amino acid
AC2117_RS03880	COG0321	lipoyl(octanoyl) transferase activity
AC2117_RS03885	COG2921	Belongs to the UPF0250 family
AC2117_RS03925	COG2009	succinate dehydrogenase
AC2117_RS03930	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AC2117_RS03935	COG1053	succinate dehydrogenase
AC2117_RS03940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AC2117_RS03965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC2117_RS03985	COG2354	Protein conserved in bacteria
AC2117_RS03990	COG2321	neutral zinc metallopeptidase
AC2117_RS04010	COG2843	Capsule synthesis protein
AC2117_RS04025	COG0589	response to stress
AC2117_RS04045	COG0505	Belongs to the CarA family
AC2117_RS04075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC2117_RS04080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AC2117_RS04120	COG2264	protein methyltransferase activity
AC2117_RS04130	COG0477	Major facilitator Superfamily
AC2117_RS04135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AC2117_RS04150	COG1597	lipid kinase activity
AC2117_RS04155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AC2117_RS04180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC2117_RS04185	COG0584	glycerophosphoryl diester phosphodiesterase
AC2117_RS04205	COG0741	lytic transglycosylase activity
AC2117_RS04225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC2117_RS04310	COG0778	Nitroreductase
AC2117_RS04315	COG1929	Belongs to the glycerate kinase type-1 family
AC2117_RS04325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AC2117_RS04355	COG1115	amino acid carrier protein
AC2117_RS04360	COG1113	amino acid transport
AC2117_RS04370	COG0019	diaminopimelate decarboxylase activity
AC2117_RS04385	COG1280	lysine exporter protein (LysE YggA)
AC2117_RS04390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AC2117_RS04420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC2117_RS04445	COG0697	spore germination
AC2117_RS04455	COG4591	ABC-type transport system involved in lipoprotein release permease component
AC2117_RS04460	COG1136	(ABC) transporter
AC2117_RS04465	COG0658	competence protein
AC2117_RS04465	COG2333	competence protein COMEC
AC2117_RS04475	COG0616	signal peptide processing
AC2117_RS04475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AC2117_RS04485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AC2117_RS04495	COG0628	permease
AC2117_RS04535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC2117_RS04555	COG0823	Involved in the tonB-independent uptake of proteins
AC2117_RS04575	COG0824	Thioesterase
AC2117_RS04595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AC2117_RS04595	COG0047	phosphoribosylformylglycinamidine synthase activity
AC2117_RS04600	COG2814	Major facilitator Superfamily
AC2117_RS04605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AC2117_RS04610	COG1024	Enoyl-CoA hydratase
AC2117_RS04615	COG1056	cytidyltransferase-related domain
AC2117_RS04615	COG1051	belongs to the nudix hydrolase family
AC2117_RS04630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC2117_RS04645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AC2117_RS04660	COG4625	pathogenesis
AC2117_RS04665	COG0583	DNA-binding transcription factor activity
AC2117_RS04670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AC2117_RS04675	COG4208	sulfate ABC transporter
AC2117_RS04680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AC2117_RS04690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AC2117_RS04695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC2117_RS04700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AC2117_RS04720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC2117_RS04730	COG0481	GTPase activity
AC2117_RS04735	COG0681	Belongs to the peptidase S26 family
AC2117_RS04745	COG0571	ribonuclease III activity
AC2117_RS04750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AC2117_RS04765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AC2117_RS04775	COG4221	oxidoreductase activity
AC2117_RS04805	COG0436	Aminotransferase
AC2117_RS04830	COG0556	nucleotide-excision repair
AC2117_RS04885	COG2070	2-Nitropropane dioxygenase
AC2117_RS04915	COG1215	transferase activity, transferring glycosyl groups
AC2117_RS04930	COG0415	Belongs to the DNA photolyase family
AC2117_RS04940	COG1252	NADH dehydrogenase
AC2117_RS04945	COG1686	Belongs to the peptidase S11 family
AC2117_RS04960	COG1187	pseudouridine synthase activity
AC2117_RS04970	COG0477	Major facilitator Superfamily
AC2117_RS04975	COG0583	DNA-binding transcription factor activity
AC2117_RS04980	COG1823	symporter activity
AC2117_RS04990	COG0612	Peptidase, M16
AC2117_RS05015	COG0352	thiamine-phosphate diphosphorylase activity
AC2117_RS05050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC2117_RS05075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AC2117_RS05080	COG0076	glutamate decarboxylase activity
AC2117_RS05090	COG1522	sequence-specific DNA binding
AC2117_RS05095	COG3961	Belongs to the TPP enzyme family
AC2117_RS05100	COG1113	amino acid transport
AC2117_RS05105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AC2117_RS05110	COG0573	inorganic phosphate transmembrane transporter activity
AC2117_RS05120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AC2117_RS05125	COG0616	signal peptide processing
AC2117_RS05165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AC2117_RS05170	COG1686	Belongs to the peptidase S11 family
AC2117_RS05190	COG1388	LysM domain
AC2117_RS05190	COG4942	peptidase
AC2117_RS05195	COG0583	DNA-binding transcription factor activity
AC2117_RS05200	COG1067	ATP-dependent peptidase activity
AC2117_RS05220	COG0254	rRNA binding
AC2117_RS05240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC2117_RS05245	COG1966	Carbon starvation protein
AC2117_RS05250	COG2879	small protein
AC2117_RS05280	COG2801	Transposase and inactivated derivatives
AC2117_RS05295	COG2423	ornithine cyclodeaminase activity
AC2117_RS05305	COG2964	Protein conserved in bacteria
AC2117_RS05315	COG1741	Belongs to the pirin family
AC2117_RS05335	COG3739	integral membrane protein
AC2117_RS05355	COG0302	gtp cyclohydrolase
AC2117_RS05375	COG0512	Glutamine amidotransferase of anthranilate synthase
AC2117_RS05395	COG0174	glutamine synthetase
AC2117_RS05405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AC2117_RS05440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AC2117_RS05445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AC2117_RS05450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC2117_RS05460	COG0280	phosphate acetyltransferase
AC2117_RS05460	COG0281	malic enzyme
AC2117_RS05470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC2117_RS05475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AC2117_RS05480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AC2117_RS05495	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS05500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AC2117_RS05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC2117_RS05515	COG2223	nitrite transmembrane transporter activity
AC2117_RS05525	COG0024	Methionine aminopeptidase
AC2117_RS05530	COG0052	Belongs to the universal ribosomal protein uS2 family
AC2117_RS05545	COG2207	Transcriptional regulator
AC2117_RS05570	COG2951	lytic endotransglycosylase activity
AC2117_RS05575	COG0772	Belongs to the SEDS family
AC2117_RS05590	COG0842	Transport permease protein
AC2117_RS05595	COG1131	(ABC) transporter
AC2117_RS05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC2117_RS05660	COG4160	amino acid transport
AC2117_RS05665	COG4598	ABC transporter
AC2117_RS05675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC2117_RS05680	COG0384	phenazine biosynthesis protein PhzF
AC2117_RS05690	COG1720	tRNA m6t6A37 methyltransferase activity
AC2117_RS05700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC2117_RS05715	COG0642	Histidine kinase
AC2117_RS05725	COG0494	nUDIX hydrolase
AC2117_RS05735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC2117_RS05740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AC2117_RS05745	COG3139	Protein of unknown function (DUF1315)
AC2117_RS05755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AC2117_RS05765	COG1301	dicarboxylic acid transport
AC2117_RS05770	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS05780	COG2819	hydrolase of the alpha beta superfamily
AC2117_RS05790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AC2117_RS05800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC2117_RS05805	COG2195	Cleaves the N-terminal amino acid of tripeptides
AC2117_RS05810	COG1234	tRNA 3'-trailer cleavage
AC2117_RS05840	COG2363	Small membrane protein
AC2117_RS05860	COG0513	Belongs to the DEAD box helicase family
AC2117_RS05870	COG0778	Nitroreductase
AC2117_RS05900	COG1286	toxin biosynthetic process
AC2117_RS05925	COG4783	chaperone-mediated protein folding
AC2117_RS05930	COG1610	YqeY-like protein
AC2117_RS05960	COG0515	serine threonine protein kinase
AC2117_RS05960	COG2815	serine threonine protein kinase
AC2117_RS05985	COG1278	Cold shock
AC2117_RS06010	COG0534	Mate efflux family protein
AC2117_RS06030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC2117_RS06035	COG4221	oxidoreductase activity
AC2117_RS06040	COG1733	regulation of RNA biosynthetic process
AC2117_RS06045	COG2085	NADP oxidoreductase coenzyme F420-dependent
AC2117_RS06060	COG1309	transcriptional regulator
AC2117_RS06075	COG3243	poly(R)-hydroxyalkanoic acid synthase
AC2117_RS06080	COG0786	glutamate:sodium symporter activity
AC2117_RS06085	COG0475	glutathione-regulated potassium exporter activity
AC2117_RS06085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC2117_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS06125	COG2995	paraquat-inducible protein a
AC2117_RS06130	COG3008	intermembrane lipid transfer
AC2117_RS06130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC2117_RS06140	COG2351	hydroxyisourate hydrolase activity
AC2117_RS06180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC2117_RS06190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC2117_RS06195	COG0642	Histidine kinase
AC2117_RS06200	COG0745	RESPONSE REGULATOR receiver
AC2117_RS06225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AC2117_RS06230	COG1794	racemase activity, acting on amino acids and derivatives
AC2117_RS06240	COG2175	clavaminate synthase activity
AC2117_RS06245	COG3246	L-lysine catabolic process to acetate
AC2117_RS06265	COG2855	membrane
AC2117_RS06315	COG1301	dicarboxylic acid transport
AC2117_RS06330	COG2011	ABC-type metal ion transport system permease component
AC2117_RS06335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AC2117_RS06340	COG1464	Belongs to the NlpA lipoprotein family
AC2117_RS06350	COG0151	Belongs to the GarS family
AC2117_RS06355	COG0138	bifunctional purine biosynthesis protein purh
AC2117_RS06360	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AC2117_RS06390	COG2308	Evidence 4 Homologs of previously reported genes of
AC2117_RS06400	COG1305	Transglutaminase-like
AC2117_RS06410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AC2117_RS06415	COG0305	Participates in initiation and elongation during chromosome replication
AC2117_RS06440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AC2117_RS06450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AC2117_RS06455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AC2117_RS06480	COG1649	PFAM Uncharacterised BCR, COG1649
AC2117_RS06480	COG0726	polysaccharide deacetylase
AC2117_RS06485	COG1215	transferase activity, transferring glycosyl groups
AC2117_RS06490	COG3658	cytochrome
AC2117_RS06500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC2117_RS06520	COG0583	DNA-binding transcription factor activity
AC2117_RS06535	COG2890	protein-(glutamine-N5) methyltransferase activity
AC2117_RS06540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC2117_RS06545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AC2117_RS06560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC2117_RS06575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AC2117_RS06585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AC2117_RS06590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AC2117_RS06600	COG2205	protein histidine kinase activity
AC2117_RS06605	COG0745	RESPONSE REGULATOR receiver
AC2117_RS06610	COG0174	glutamine synthetase
AC2117_RS06630	COG0729	surface antigen
AC2117_RS06640	COG2706	6-phosphogluconolactonase activity
AC2117_RS06675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC2117_RS06680	COG2814	Major facilitator Superfamily
AC2117_RS06690	COG0583	DNA-binding transcription factor activity
AC2117_RS06705	COG1187	pseudouridine synthase activity
AC2117_RS06725	COG0802	atpase or kinase
AC2117_RS06730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AC2117_RS06740	COG1923	regulation of RNA biosynthetic process
AC2117_RS06745	COG0697	spore germination
AC2117_RS06760	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC2117_RS06770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC2117_RS06775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC2117_RS06775	COG0519	Catalyzes the synthesis of GMP from XMP
AC2117_RS06780	COG4302	ethanolamine ammonia-lyase activity
AC2117_RS06785	COG4303	Ethanolamine ammonia lyase large subunit
AC2117_RS06790	COG0531	amino acid
AC2117_RS06810	COG1454	alcohol dehydrogenase
AC2117_RS06815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AC2117_RS06825	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AC2117_RS06845	COG0308	aminopeptidase N
AC2117_RS06885	COG1605	Chorismate mutase
AC2117_RS06900	COG2801	Transposase and inactivated derivatives
AC2117_RS06915	COG4772	TonB-dependent receptor
AC2117_RS06920	COG4774	siderophore transport
AC2117_RS06980	COG1733	regulation of RNA biosynthetic process
AC2117_RS07005	COG0583	DNA-binding transcription factor activity
AC2117_RS07020	COG3111	PFAM Bacterial OB fold (BOF) protein
AC2117_RS07040	COG0488	(ABC) transporter
AC2117_RS07045	COG0589	response to stress
AC2117_RS07065	COG3135	benzoate transporter
AC2117_RS07070	COG1522	sequence-specific DNA binding
AC2117_RS07080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AC2117_RS07085	COG0583	DNA-binding transcription factor activity
AC2117_RS07095	COG0183	Belongs to the thiolase family
AC2117_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS07105	COG2030	dehydratase
AC2117_RS07135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AC2117_RS07145	COG0824	Thioesterase
AC2117_RS07150	COG1454	alcohol dehydrogenase
AC2117_RS07175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AC2117_RS07205	COG0069	glutamate synthase activity
AC2117_RS07245	COG1309	transcriptional regulator
AC2117_RS07250	COG2814	Major facilitator Superfamily
AC2117_RS07265	COG0511	ligase activity, forming carbon-carbon bonds
AC2117_RS07290	COG4264	IucA IucC family
AC2117_RS07300	COG4264	IucA IucC family
AC2117_RS07305	COG2423	ornithine cyclodeaminase activity
AC2117_RS07310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AC2117_RS07320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AC2117_RS07320	COG1116	anion transmembrane transporter activity
AC2117_RS07335	COG2146	nitrite reductase [NAD(P)H] activity
AC2117_RS07335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC2117_RS07340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC2117_RS07345	COG0243	molybdopterin cofactor binding
AC2117_RS07355	COG0243	molybdopterin cofactor binding
AC2117_RS07375	COG0521	Mo-molybdopterin cofactor biosynthetic process
AC2117_RS07375	COG0315	cyclic pyranopterin monophosphate synthase activity
AC2117_RS07380	COG0303	'Molybdopterin
AC2117_RS07390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC2117_RS07395	COG0697	spore germination
AC2117_RS07420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AC2117_RS07440	COG1335	isochorismatase
AC2117_RS07480	COG2204	response regulator
AC2117_RS07485	COG3852	Histidine kinase
AC2117_RS07510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AC2117_RS07515	COG0575	Belongs to the CDS family
AC2117_RS07550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC2117_RS07565	COG2137	regulation of response to DNA damage stimulus
AC2117_RS07575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AC2117_RS07580	COG1011	Hydrolase
AC2117_RS07645	COG0270	DNA (cytosine-5-)-methyltransferase activity
AC2117_RS07655	COG1484	DNA-dependent DNA replication
AC2117_RS07715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC2117_RS07735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC2117_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS07745	COG3118	belongs to the thioredoxin family
AC2117_RS07750	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS07760	COG1294	oxidase, subunit
AC2117_RS07765	COG1271	oxidase subunit
AC2117_RS07945	COG3550	peptidyl-serine autophosphorylation
AC2117_RS08150	COG1522	sequence-specific DNA binding
AC2117_RS08160	COG1113	amino acid transport
AC2117_RS08180	COG0659	secondary active sulfate transmembrane transporter activity
AC2117_RS08200	COG5001	Diguanylate cyclase
AC2117_RS08200	COG3300	MHYT domain
AC2117_RS08215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC2117_RS08215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC2117_RS08215	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AC2117_RS08220	COG1105	Belongs to the carbohydrate kinase PfkB family
AC2117_RS08225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC2117_RS08225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AC2117_RS08255	COG0024	Methionine aminopeptidase
AC2117_RS08260	COG0583	DNA-binding transcription factor activity
AC2117_RS08275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC2117_RS08280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AC2117_RS08280	COG0517	IMP dehydrogenase activity
AC2117_RS08305	COG0552	protein localization to endoplasmic reticulum
AC2117_RS08330	COG4890	Cyd operon protein YbgT
AC2117_RS08335	COG1294	oxidase, subunit
AC2117_RS08350	COG1585	Membrane protein implicated in regulation of membrane protease activity
AC2117_RS08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC2117_RS08380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AC2117_RS08385	COG0569	domain protein
AC2117_RS08390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AC2117_RS08420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AC2117_RS08425	COG0542	response to heat
AC2117_RS08435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AC2117_RS08450	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC2117_RS08450	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS08490	COG0148	phosphopyruvate hydratase activity
AC2117_RS08495	COG2323	membrane
AC2117_RS08510	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AC2117_RS08520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AC2117_RS08525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AC2117_RS08530	COG0183	Belongs to the thiolase family
AC2117_RS08535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AC2117_RS08540	COG0596	Alpha beta hydrolase
AC2117_RS08545	COG2271	Major facilitator Superfamily
AC2117_RS08550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC2117_RS08555	COG3485	protocatechuate 3,4-dioxygenase
AC2117_RS08560	COG3485	protocatechuate 3,4-dioxygenase
AC2117_RS08565	COG0710	3-dehydroquinate dehydratase activity
AC2117_RS08570	COG3420	alginic acid biosynthetic process
AC2117_RS08575	COG3659	wide pore channel activity
AC2117_RS08580	COG4993	Dehydrogenase
AC2117_RS08605	COG1414	Transcriptional regulator
AC2117_RS08610	COG0583	DNA-binding transcription factor activity
AC2117_RS08615	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS08640	COG2814	Major facilitator Superfamily
AC2117_RS08650	COG0154	amidase activity
AC2117_RS08680	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS08690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC2117_RS08700	COG3733	amine oxidase
AC2117_RS08710	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS08720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC2117_RS08725	COG0183	Belongs to the thiolase family
AC2117_RS08730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AC2117_RS08735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AC2117_RS08745	COG4829	muconolactone delta-isomerase
AC2117_RS08750	COG4948	Mandelate Racemase Muconate Lactonizing
AC2117_RS08755	COG0583	DNA-binding transcription factor activity
AC2117_RS08765	COG2186	Transcriptional regulator
AC2117_RS08785	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS08810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AC2117_RS08845	COG1309	transcriptional regulator
AC2117_RS08860	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS08865	COG0129	dihydroxy-acid dehydratase activity
AC2117_RS08875	COG0583	DNA-binding transcription factor activity
AC2117_RS08880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC2117_RS08890	COG2084	Dehydrogenase
AC2117_RS08895	COG0604	alcohol dehydrogenase
AC2117_RS08895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC2117_RS08895	COG3321	synthase
AC2117_RS08895	COG4221	oxidoreductase activity
AC2117_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS08920	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS08930	COG1733	regulation of RNA biosynthetic process
AC2117_RS08995	COG1566	PFAM secretion protein HlyD family protein
AC2117_RS09020	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AC2117_RS09030	COG1278	Cold shock
AC2117_RS09040	COG0583	DNA-binding transcription factor activity
AC2117_RS09045	COG2207	Transcriptional regulator
AC2117_RS09050	COG1064	alcohol dehydrogenase
AC2117_RS09065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC2117_RS09070	COG1120	ATPase activity
AC2117_RS09100	COG4221	oxidoreductase activity
AC2117_RS09105	COG0702	epimerase
AC2117_RS09110	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS09115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC2117_RS09120	COG1280	lysine exporter protein (LysE YggA)
AC2117_RS09130	COG1301	dicarboxylic acid transport
AC2117_RS09140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC2117_RS09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AC2117_RS09250	COG0477	Major facilitator Superfamily
AC2117_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS09260	COG0371	Dehydrogenase
AC2117_RS09270	COG0583	DNA-binding transcription factor activity
AC2117_RS09275	COG4628	conserved protein (DUF2132)
AC2117_RS09290	COG3539	Fimbrial protein
AC2117_RS09315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AC2117_RS09325	COG0753	catalase activity
AC2117_RS09355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AC2117_RS09360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC2117_RS09420	COG4771	TonB-dependent receptor
AC2117_RS09425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC2117_RS09430	COG3433	isochorismatase activity
AC2117_RS09430	COG1535	isochorismatase
AC2117_RS09435	COG1021	2,3-dihydroxybenzoate-AMP ligase
AC2117_RS09440	COG1169	isochorismate synthase
AC2117_RS09445	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS09455	COG3251	PFAM MbtH domain protein
AC2117_RS09460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC2117_RS09490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AC2117_RS09495	COG4149	molybdate abc transporter
AC2117_RS09500	COG0725	ABC transporter, periplasmic molybdate-binding protein
AC2117_RS09510	COG4638	Rieske (2fe-2S)
AC2117_RS09515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AC2117_RS09520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC2117_RS09520	COG0543	2 iron, 2 sulfur cluster binding
AC2117_RS09535	COG2207	Transcriptional regulator
AC2117_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS09545	COG2610	gluconate transmembrane transporter activity
AC2117_RS09560	COG0583	DNA-binding transcription factor activity
AC2117_RS09575	COG2031	fatty acid transporter
AC2117_RS09580	COG0183	Belongs to the thiolase family
AC2117_RS09585	COG0583	DNA-binding transcription factor activity
AC2117_RS09590	COG0583	DNA-binding transcription factor activity
AC2117_RS09605	COG1027	Aspartate ammonia-lyase
AC2117_RS09615	COG0477	Major facilitator Superfamily
AC2117_RS09635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC2117_RS09640	COG4521	taurine ABC transporter
AC2117_RS09650	COG2081	HI0933 family
AC2117_RS09655	COG2188	Transcriptional regulator
AC2117_RS09665	COG3708	Transcriptional regulator
AC2117_RS09665	COG2207	Transcriptional regulator
AC2117_RS09680	COG0730	response to heat
AC2117_RS09700	COG3781	membrane
AC2117_RS09705	COG1063	alcohol dehydrogenase
AC2117_RS09715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC2117_RS09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC2117_RS09725	COG0022	dehydrogenase e1 component
AC2117_RS09730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AC2117_RS09735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AC2117_RS09750	COG3706	GGDEF domain
AC2117_RS09770	COG0133	tryptophan synthase activity
AC2117_RS09780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC2117_RS09815	COG0583	DNA-binding transcription factor activity
AC2117_RS09820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AC2117_RS09830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AC2117_RS09885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC2117_RS09890	COG4773	Receptor
AC2117_RS09910	COG0730	response to heat
AC2117_RS09915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AC2117_RS09965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC2117_RS09980	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS09985	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS09990	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC2117_RS09995	COG2207	Transcriptional regulator
AC2117_RS10000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC2117_RS10005	COG0776	regulation of translation
AC2117_RS10030	COG0822	iron-sulfur transferase activity
AC2117_RS10035	COG0316	Belongs to the HesB IscA family
AC2117_RS10065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AC2117_RS10085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AC2117_RS10090	COG0702	epimerase
AC2117_RS10120	COG4172	Belongs to the ABC transporter superfamily
AC2117_RS10130	COG0601	transmembrane transport
AC2117_RS10135	COG0339	signal peptide processing
AC2117_RS10140	COG4166	transmembrane transport
AC2117_RS10175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AC2117_RS10180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AC2117_RS10195	COG2431	L-lysine efflux transmembrane transporter activity
AC2117_RS10210	COG0776	regulation of translation
AC2117_RS10275	COG0084	hydrolase, TatD family'
AC2117_RS10295	COG1663	tetraacyldisaccharide 4'-kinase activity
AC2117_RS10300	COG1132	(ABC) transporter
AC2117_RS10310	COG0811	peptide transport
AC2117_RS10315	COG1475	DNA binding
AC2117_RS10320	COG1192	Involved in chromosome partitioning
AC2117_RS10330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AC2117_RS10345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC2117_RS10350	COG0191	fructose-bisphosphate aldolase activity
AC2117_RS10370	COG0424	maF-like protein
AC2117_RS10375	COG2850	peptidyl-arginine hydroxylation
AC2117_RS10385	COG0640	Transcriptional regulator
AC2117_RS10395	COG3619	membrane
AC2117_RS10400	COG3122	Protein conserved in bacteria
AC2117_RS10405	COG1132	(ABC) transporter
AC2117_RS10425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AC2117_RS10430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AC2117_RS10440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AC2117_RS10440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AC2117_RS10440	COG0506	proline dehydrogenase activity
AC2117_RS10445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AC2117_RS10460	COG3698	Phosphodiester glycosidase
AC2117_RS10470	COG2353	YceI-like domain
AC2117_RS10480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AC2117_RS10525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AC2117_RS10525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC2117_RS10550	COG3539	Fimbrial protein
AC2117_RS10555	COG3121	Chaperone
AC2117_RS10585	COG0583	DNA-binding transcription factor activity
AC2117_RS10590	COG0697	spore germination
AC2117_RS10600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AC2117_RS10610	COG0583	DNA-binding transcription factor activity
AC2117_RS10625	COG1309	transcriptional regulator
AC2117_RS10640	COG1522	sequence-specific DNA binding
AC2117_RS10650	COG1126	abc transporter atp-binding protein
AC2117_RS10655	COG0765	amino acid transport
AC2117_RS10660	COG0765	amino acid transport
AC2117_RS10690	COG1464	Belongs to the NlpA lipoprotein family
AC2117_RS10700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AC2117_RS10705	COG2011	ABC-type metal ion transport system permease component
AC2117_RS10710	COG0012	GTP binding
AC2117_RS10735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AC2117_RS10770	COG1917	Cupin 2, conserved barrel domain protein
AC2117_RS10770	COG2207	Transcriptional regulator
AC2117_RS10775	COG0386	Belongs to the glutathione peroxidase family
AC2117_RS10785	COG0436	Aminotransferase
AC2117_RS10790	COG1301	dicarboxylic acid transport
AC2117_RS10825	COG3634	alkyl hydroperoxide reductase activity
AC2117_RS10840	COG0583	DNA-binding transcription factor activity
AC2117_RS10845	COG0431	NADPH-dependent FMN reductase
AC2117_RS10850	COG0798	PFAM Bile acid sodium symporter
AC2117_RS10860	COG0640	Transcriptional regulator
AC2117_RS10875	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AC2117_RS10885	COG0583	DNA-binding transcription factor activity
AC2117_RS10890	COG2175	clavaminate synthase activity
AC2117_RS10895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC2117_RS10900	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AC2117_RS10905	COG4521	taurine ABC transporter
AC2117_RS10915	COG0477	Major facilitator Superfamily
AC2117_RS10940	COG1271	oxidase subunit
AC2117_RS10945	COG1294	oxidase, subunit
AC2117_RS10955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC2117_RS10975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AC2117_RS10995	COG3052	prosthetic group binding
AC2117_RS11000	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AC2117_RS11025	COG1346	cytolysis
AC2117_RS11035	COG0583	DNA-binding transcription factor activity
AC2117_RS11040	COG0625	glutathione transferase activity
AC2117_RS11045	COG0625	glutathione transferase activity
AC2117_RS11070	COG1045	serine acetyltransferase
AC2117_RS11075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC2117_RS11080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AC2117_RS11090	COG1280	lysine exporter protein (LysE YggA)
AC2117_RS11095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AC2117_RS11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC2117_RS11115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC2117_RS11125	COG0765	amino acid transport
AC2117_RS11130	COG0765	amino acid transport
AC2117_RS11140	COG2388	GCN5-related N-acetyl-transferase
AC2117_RS11190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC2117_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS11255	COG0583	DNA-binding transcription factor activity
AC2117_RS11270	COG2814	Major facilitator Superfamily
AC2117_RS11285	COG0318	PFAM AMP-dependent synthetase and ligase
AC2117_RS11290	COG1309	transcriptional regulator
AC2117_RS11295	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS11300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AC2117_RS11305	COG1024	Enoyl-CoA hydratase
AC2117_RS11310	COG4770	biotin carboxylase activity
AC2117_RS11320	COG0583	DNA-binding transcription factor activity
AC2117_RS11335	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS11345	COG2814	Major facilitator Superfamily
AC2117_RS11355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AC2117_RS11360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AC2117_RS11365	COG2814	Major facilitator Superfamily
AC2117_RS11370	COG2814	Major facilitator Superfamily
AC2117_RS11375	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS11380	COG1024	Enoyl-CoA hydratase
AC2117_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS11390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC2117_RS11395	COG0183	Belongs to the thiolase family
AC2117_RS11405	COG2814	Major facilitator Superfamily
AC2117_RS11415	COG1024	Enoyl-CoA hydratase
AC2117_RS11425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC2117_RS11430	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS11435	COG2814	Major facilitator Superfamily
AC2117_RS11440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC2117_RS11445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AC2117_RS11460	COG3842	ATPase activity
AC2117_RS11465	COG1840	ABC-type Fe3 transport system, periplasmic component
AC2117_RS11475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC2117_RS11480	COG1414	Transcriptional regulator
AC2117_RS11495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC2117_RS11500	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS11510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AC2117_RS11520	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS11525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC2117_RS11530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC2117_RS11535	COG2267	carboxylic ester hydrolase activity
AC2117_RS11585	COG1760	l-serine dehydratase
AC2117_RS11595	COG0789	Transcriptional regulator
AC2117_RS11605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC2117_RS11610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC2117_RS11765	COG0477	Major facilitator Superfamily
AC2117_RS11780	COG1116	anion transmembrane transporter activity
AC2117_RS11785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC2117_RS11795	COG0864	Transcriptional regulator
AC2117_RS11805	COG1733	regulation of RNA biosynthetic process
AC2117_RS11810	COG2249	NAD(P)H dehydrogenase (quinone) activity
AC2117_RS11815	COG0439	Biotin carboxylase
AC2117_RS11830	COG1063	alcohol dehydrogenase
AC2117_RS11835	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC2117_RS11865	COG0038	chloride channel
AC2117_RS11870	COG4770	biotin carboxylase activity
AC2117_RS11890	COG1914	H( )-stimulated, divalent metal cation uptake system
AC2117_RS11895	COG0583	DNA-binding transcription factor activity
AC2117_RS11905	COG1595	DNA-templated transcription, initiation
AC2117_RS11915	COG3220	belongs to the UPF0276 family
AC2117_RS11990	COG2814	Major facilitator Superfamily
AC2117_RS12000	COG0583	DNA-binding transcription factor activity
AC2117_RS12005	COG1309	transcriptional regulator
AC2117_RS12020	COG0657	acetylesterase activity
AC2117_RS12040	COG1595	DNA-templated transcription, initiation
AC2117_RS12045	COG3712	iron ion homeostasis
AC2117_RS12065	COG0402	S-adenosylhomocysteine deaminase activity
AC2117_RS12070	COG0583	DNA-binding transcription factor activity
AC2117_RS12100	COG2801	Transposase and inactivated derivatives
AC2117_RS12125	COG2050	protein possibly involved in aromatic compounds catabolism
AC2117_RS12135	COG3327	negative regulation of DNA-templated transcription, initiation
AC2117_RS12140	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AC2117_RS12145	COG0183	Belongs to the thiolase family
AC2117_RS12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC2117_RS12155	COG1024	Enoyl-CoA hydratase
AC2117_RS12160	COG1024	Enoyl-CoA hydratase
AC2117_RS12165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC2117_RS12170	COG2151	metal-sulfur cluster biosynthetic enzyme
AC2117_RS12175	COG3396	Phenylacetate-CoA oxygenase
AC2117_RS12180	COG3460	Phenylacetate-CoA oxygenase
AC2117_RS12185	COG3396	Phenylacetate-CoA oxygenase
AC2117_RS12190	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS12190	COG2030	dehydratase
AC2117_RS12205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AC2117_RS12220	COG4122	O-methyltransferase activity
AC2117_RS12250	COG1538	Outer membrane efflux protein
AC2117_RS12255	COG1137	ATPase activity
AC2117_RS12260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AC2117_RS12270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AC2117_RS12325	COG2814	Major facilitator Superfamily
AC2117_RS12355	COG0668	transmembrane transport
AC2117_RS12405	COG2226	methyltransferase
AC2117_RS12410	COG1011	Hydrolase
AC2117_RS12435	COG1278	Cold shock
AC2117_RS12440	COG1560	Kdo2-lipid A biosynthetic process
AC2117_RS12445	COG1280	lysine exporter protein (LysE YggA)
AC2117_RS12480	COG1570	exodeoxyribonuclease VII activity
AC2117_RS12525	COG0583	DNA-binding transcription factor activity
AC2117_RS12535	COG4638	Rieske (2fe-2S)
AC2117_RS12540	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AC2117_RS12545	COG0543	2 iron, 2 sulfur cluster binding
AC2117_RS12545	COG0633	Ferredoxin
AC2117_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS12555	COG3135	benzoate transporter
AC2117_RS12560	COG2814	Major facilitator Superfamily
AC2117_RS12575	COG1643	Atp-dependent helicase
AC2117_RS12580	COG0450	alkyl hydroperoxide reductase
AC2117_RS12600	COG3634	alkyl hydroperoxide reductase activity
AC2117_RS12620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AC2117_RS12625	COG0625	glutathione transferase activity
AC2117_RS12635	COG2885	chlorophyll binding
AC2117_RS12670	COG0542	response to heat
AC2117_RS12690	COG1765	OsmC-like protein
AC2117_RS12700	COG0667	Aldo Keto reductase
AC2117_RS12715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AC2117_RS12725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AC2117_RS12735	COG0527	aspartate kinase activity
AC2117_RS12745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AC2117_RS12755	COG3038	cytochrome b561
AC2117_RS12760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AC2117_RS12765	COG2252	PERMEase
AC2117_RS12775	COG1741	Belongs to the pirin family
AC2117_RS12780	COG1309	transcriptional regulator
AC2117_RS12795	COG2072	flavoprotein involved in K transport
AC2117_RS12800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AC2117_RS12830	COG1944	ATP diphosphatase activity
AC2117_RS12850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC2117_RS12865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC2117_RS12880	COG2814	Major facilitator Superfamily
AC2117_RS12885	COG1024	Enoyl-CoA hydratase
AC2117_RS12890	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS12900	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS12925	COG2186	Transcriptional regulator
AC2117_RS12930	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS12940	COG4948	Mandelate Racemase Muconate Lactonizing
AC2117_RS12945	COG2271	Major facilitator Superfamily
AC2117_RS12950	COG2721	sulfolactate sulfo-lyase activity
AC2117_RS12955	COG0697	spore germination
AC2117_RS12975	COG1113	amino acid transport
AC2117_RS12995	COG1012	belongs to the aldehyde dehydrogenase family
AC2117_RS13015	COG0531	amino acid
AC2117_RS13025	COG1113	amino acid transport
AC2117_RS13050	COG1309	transcriptional regulator
AC2117_RS13060	COG4269	membrane
AC2117_RS13080	COG1902	pentaerythritol trinitrate reductase activity
AC2117_RS13080	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC2117_RS13090	COG4251	negative regulation of phosphorylation
AC2117_RS13090	COG2203	Gaf domain
AC2117_RS13090	COG3706	GGDEF domain
AC2117_RS13090	COG5001	Diguanylate cyclase
AC2117_RS13100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC2117_RS13125	COG4172	Belongs to the ABC transporter superfamily
AC2117_RS13130	COG4239	(ABC) transporter, permease
AC2117_RS13135	COG4174	ABC transporter (Permease)
AC2117_RS13140	COG4166	transmembrane transport
AC2117_RS13145	COG0741	lytic transglycosylase activity
AC2117_RS13145	COG1388	LysM domain
AC2117_RS13145	COG0741	lytic transglycosylase activity
AC2117_RS13145	COG1388	LysM domain
AC2117_RS13185	COG0583	DNA-binding transcription factor activity
AC2117_RS13190	COG1279	arginine transmembrane transporter activity
AC2117_RS13200	COG0789	Transcriptional regulator
AC2117_RS13210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC2117_RS13215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC2117_RS13220	COG0006	proline dipeptidase activity
AC2117_RS13380	COG3566	protein conserved in bacteria
AC2117_RS13395	COG3567	Phage-associated protein, HI1409 family
AC2117_RS13400	COG5410	chromosome segregation
AC2117_RS13525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AC2117_RS13540	COG3384	dioxygenase
AC2117_RS13550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AC2117_RS13555	COG2878	Part of a membrane complex involved in electron transport
AC2117_RS13560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AC2117_RS13580	COG0768	penicillin binding
AC2117_RS13585	COG0742	ribosomal rna small subunit methyltransferase
AC2117_RS13600	COG0830	nickel cation binding
AC2117_RS13610	COG0804	urea catabolic process
AC2117_RS13635	COG3015	lipoprotein NlpE involved in copper resistance
AC2117_RS13650	COG1253	flavin adenine dinucleotide binding
AC2117_RS13655	COG2851	Citrate transporter
AC2117_RS13705	COG1773	rubredoxin
AC2117_RS13710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC2117_RS13720	COG0583	DNA-binding transcription factor activity
AC2117_RS13750	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AC2117_RS13755	COG4181	ATPase activity
AC2117_RS13800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC2117_RS13820	COG0306	phosphate transporter
AC2117_RS13840	COG3958	Transketolase
AC2117_RS13845	COG3959	Transketolase, thiamine diphosphate binding domain
AC2117_RS13850	COG2271	Major facilitator Superfamily
AC2117_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS13860	COG0583	DNA-binding transcription factor activity
AC2117_RS13880	COG2223	nitrite transmembrane transporter activity
AC2117_RS13890	COG2066	Belongs to the glutaminase family
AC2117_RS13895	COG0242	peptide deformylase activity
AC2117_RS13900	COG0477	Major facilitator Superfamily
AC2117_RS13910	COG0028	Belongs to the TPP enzyme family
AC2117_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS13930	COG2267	carboxylic ester hydrolase activity
AC2117_RS13940	COG2271	Major facilitator Superfamily
AC2117_RS13975	COG1414	Transcriptional regulator
AC2117_RS13995	COG1024	Enoyl-CoA hydratase
AC2117_RS14005	COG1309	transcriptional regulator
AC2117_RS14015	COG1215	transferase activity, transferring glycosyl groups
AC2117_RS14020	COG0726	polysaccharide deacetylase
AC2117_RS14020	COG1649	PFAM Uncharacterised BCR, COG1649
AC2117_RS14030	COG4681	YaeQ
AC2117_RS14040	COG0523	cobalamin synthesis protein
AC2117_RS14050	COG1607	acyl-coa hydrolase
AC2117_RS14060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC2117_RS14065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC2117_RS14070	COG1309	transcriptional regulator
AC2117_RS14095	COG2040	homocysteine
AC2117_RS14100	COG0531	amino acid
AC2117_RS14155	COG1595	DNA-templated transcription, initiation
AC2117_RS14165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC2117_RS14170	COG0477	Major facilitator Superfamily
AC2117_RS14180	COG2801	Transposase and inactivated derivatives
AC2117_RS14235	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AC2117_RS14235	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AC2117_RS14250	COG1401	restriction endodeoxyribonuclease activity
AC2117_RS14265	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AC2117_RS14275	COG0405	Gamma-glutamyltransferase
AC2117_RS14280	COG2814	Major facilitator Superfamily
AC2117_RS14285	COG1566	PFAM secretion protein HlyD family protein
AC2117_RS14290	COG2050	protein possibly involved in aromatic compounds catabolism
AC2117_RS14320	COG0420	3'-5' exonuclease activity
AC2117_RS14355	COG0735	belongs to the Fur family
AC2117_RS14360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC2117_RS14365	COG2914	Belongs to the UPF0125 (RnfH) family
AC2117_RS14385	COG0121	glutamine amidotransferase
AC2117_RS14400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC2117_RS14410	COG0210	DNA helicase
AC2117_RS14415	COG2885	chlorophyll binding
AC2117_RS14420	COG0204	Acyl-transferase
AC2117_RS14450	COG1280	lysine exporter protein (LysE YggA)
AC2117_RS14455	COG1674	ftsk spoiiie
AC2117_RS14460	COG0492	ferredoxin-NADP+ reductase activity
AC2117_RS14470	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AC2117_RS14480	COG0456	acetyltransferase
AC2117_RS14495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC2117_RS14500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AC2117_RS14505	COG0049	tRNA binding
AC2117_RS14510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AC2117_RS14525	COG1981	membrane
AC2117_RS14535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC2117_RS14535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AC2117_RS14565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC2117_RS14605	COG0358	DNA primase activity
AC2117_RS14620	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AC2117_RS14650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC2117_RS14680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AC2117_RS14690	COG0352	thiamine-phosphate diphosphorylase activity
AC2117_RS14690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AC2117_RS14690	COG0351	phosphomethylpyrimidine kinase
AC2117_RS14695	COG1652	LysM domain
AC2117_RS14720	COG1399	metal-binding, possibly nucleic acid-binding protein
AC2117_RS14725	COG3101	peptidyl-lysine hydroxylation
AC2117_RS14730	COG0009	L-threonylcarbamoyladenylate synthase
AC2117_RS14735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AC2117_RS14740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AC2117_RS14755	COG4106	trans-aconitate 2-methyltransferase activity
AC2117_RS14770	COG2226	methyltransferase
AC2117_RS14770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC2117_RS14770	COG0596	Alpha beta hydrolase
AC2117_RS14775	COG1877	trehalose-phosphatase activity
AC2117_RS14780	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AC2117_RS14785	COG2223	nitrite transmembrane transporter activity
AC2117_RS14805	COG1196	nuclear chromosome segregation
AC2117_RS14815	COG0730	response to heat
AC2117_RS14830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC2117_RS14840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC2117_RS14895	COG0489	protein tyrosine kinase activity
AC2117_RS14905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC2117_RS14905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC2117_RS14940	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AC2117_RS14945	COG2081	HI0933 family
AC2117_RS14950	COG0668	transmembrane transport
AC2117_RS14965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC2117_RS14970	COG0583	DNA-binding transcription factor activity
AC2117_RS14990	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC2117_RS14995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC2117_RS15010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC2117_RS15025	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC2117_RS15050	COG2199	diguanylate cyclase activity
AC2117_RS15065	COG0745	RESPONSE REGULATOR receiver
AC2117_RS15085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC2117_RS15135	COG0110	maltose O-acetyltransferase activity
AC2117_RS15195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC2117_RS15210	COG0583	DNA-binding transcription factor activity
AC2117_RS15270	COG0583	DNA-binding transcription factor activity
AC2117_RS15290	COG0583	DNA-binding transcription factor activity
AC2117_RS15295	COG1053	succinate dehydrogenase
AC2117_RS15310	COG1309	transcriptional regulator
AC2117_RS15315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC2117_RS15320	COG2814	Major facilitator Superfamily
AC2117_RS15325	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS15330	COG0583	DNA-binding transcription factor activity
AC2117_RS15335	COG1063	alcohol dehydrogenase
AC2117_RS15365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AC2117_RS15370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AC2117_RS15395	COG2132	Multicopper oxidase
AC2117_RS15405	COG0561	phosphatase activity
AC2117_RS15410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AC2117_RS15420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AC2117_RS15435	COG1214	PFAM Peptidase M22, glycoprotease
AC2117_RS15495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AC2117_RS15500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AC2117_RS15505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AC2117_RS15565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC2117_RS15575	COG1846	Transcriptional regulator
AC2117_RS15580	COG1764	response to oxidative stress
AC2117_RS15620	COG0037	tRNA processing
AC2117_RS15630	COG0248	Ppx GppA phosphatase
AC2117_RS15660	COG0072	phenylalanine-tRNA ligase activity
AC2117_RS15690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AC2117_RS15700	COG1238	metal cluster binding
AC2117_RS15705	COG0625	glutathione transferase activity
AC2117_RS15715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AC2117_RS15725	COG0318	PFAM AMP-dependent synthetase and ligase
AC2117_RS15730	COG3028	Belongs to the UPF0307 family
AC2117_RS15735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC2117_RS15755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC2117_RS15760	COG0617	tRNA 3'-terminal CCA addition
AC2117_RS15765	COG1555	photosystem II stabilization
AC2117_RS15770	COG3956	TIGRFAM MazG family protein
AC2117_RS15780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC2117_RS15800	COG0784	Response regulator, receiver
AC2117_RS15800	COG2205	protein histidine kinase activity
AC2117_RS15800	COG5002	protein histidine kinase activity
AC2117_RS15805	COG1024	Enoyl-CoA hydratase
AC2117_RS15810	COG2084	Dehydrogenase
AC2117_RS15815	COG3622	Belongs to the hyi family
AC2117_RS15845	COG0697	spore germination
AC2117_RS15855	COG2814	Major facilitator Superfamily
AC2117_RS15870	COG2304	oxidoreductase activity
AC2117_RS15910	COG1358	cellular component organization or biogenesis
AC2117_RS15930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC2117_RS15940	COG0583	DNA-binding transcription factor activity
AC2117_RS15950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AC2117_RS15960	COG0084	hydrolase, TatD family'
AC2117_RS15975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AC2117_RS16000	COG2801	Transposase and inactivated derivatives
AC2117_RS16010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AC2117_RS16015	COG0440	acetolactate synthase activity
AC2117_RS16020	COG0028	Belongs to the TPP enzyme family
AC2117_RS16050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC2117_RS16055	COG0577	efflux transmembrane transporter activity
AC2117_RS16055	COG1136	(ABC) transporter
AC2117_RS16075	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AC2117_RS16080	COG1162	GTPase activity
AC2117_RS16090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AC2117_RS16110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AC2117_RS16115	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS16155	COG2986	histidine ammonia-lyase
AC2117_RS16165	COG1216	Glycosyl transferase, family 2
AC2117_RS16170	COG0318	PFAM AMP-dependent synthetase and ligase
AC2117_RS16180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC2117_RS16205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC2117_RS16225	COG1426	Protein conserved in bacteria
AC2117_RS16260	COG0793	Belongs to the peptidase S41A family
AC2117_RS16280	COG2267	carboxylic ester hydrolase activity
AC2117_RS16290	COG3265	gluconokinase activity
AC2117_RS16300	COG0800	Aldolase
AC2117_RS16315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AC2117_RS16320	COG0280	phosphate acetyltransferase
AC2117_RS16320	COG0857	belongs to the CobB CobQ family
AC2117_RS16325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AC2117_RS16325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AC2117_RS16345	COG0740	serine-type endopeptidase activity
AC2117_RS16355	COG4774	siderophore transport
AC2117_RS16365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC2117_RS16375	COG2813	Specifically methylates the guanine in position
AC2117_RS16375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC2117_RS16475	COG0788	formyltetrahydrofolate deformylase activity
AC2117_RS16500	COG4651	solute:proton antiporter activity
AC2117_RS16500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC2117_RS16520	COG0724	RNA recognition motif
AC2117_RS16525	COG0210	DNA helicase
AC2117_RS16550	COG1733	regulation of RNA biosynthetic process
AC2117_RS16555	COG0604	alcohol dehydrogenase
AC2117_RS16560	COG2900	Belongs to the SlyX family
AC2117_RS16565	COG0488	(ABC) transporter
AC2117_RS16575	COG1560	Kdo2-lipid A biosynthetic process
AC2117_RS16585	COG1301	dicarboxylic acid transport
AC2117_RS16645	COG0473	3-isopropylmalate dehydrogenase activity
AC2117_RS16670	COG0583	DNA-binding transcription factor activity
AC2117_RS16710	COG0583	DNA-binding transcription factor activity
AC2117_RS16720	COG0625	glutathione transferase activity
AC2117_RS16725	COG2378	regulation of single-species biofilm formation
AC2117_RS16745	COG1530	ribonuclease E activity
AC2117_RS16750	COG0318	PFAM AMP-dependent synthetase and ligase
AC2117_RS16765	COG0583	DNA-binding transcription factor activity
AC2117_RS16770	COG4221	oxidoreductase activity
AC2117_RS16775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC2117_RS16785	COG0534	Mate efflux family protein
AC2117_RS16800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC2117_RS16830	COG0493	'glutamate synthase
AC2117_RS16830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC2117_RS16840	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AC2117_RS16845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC2117_RS16860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AC2117_RS16870	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AC2117_RS16870	COG0644	oxidoreductase
AC2117_RS16875	COG0425	Belongs to the sulfur carrier protein TusA family
AC2117_RS16880	COG4535	Mg2 and Co2 transporter CorC
AC2117_RS16890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC2117_RS16910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AC2117_RS16915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC2117_RS16915	COG0475	glutathione-regulated potassium exporter activity
AC2117_RS16920	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AC2117_RS16930	COG0484	heat shock protein binding
AC2117_RS16935	COG0789	Transcriptional regulator
AC2117_RS16940	COG0598	Magnesium transport protein CorA
AC2117_RS16945	COG1185	polyribonucleotide nucleotidyltransferase activity
AC2117_RS16955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AC2117_RS16960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AC2117_RS16965	COG1074	ATP-dependent DNA helicase activity
AC2117_RS16970	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AC2117_RS16990	COG2226	methyltransferase
AC2117_RS17000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC2117_RS17005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AC2117_RS17020	COG2111	Na H antiporter
AC2117_RS17020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC2117_RS17025	COG1006	Multisubunit Na H antiporter MnhC subunit
AC2117_RS17030	COG0651	ATP synthesis coupled electron transport
AC2117_RS17035	COG1863	multisubunit Na H antiporter MnhE subunit
AC2117_RS17040	COG2212	antiporter activity
AC2117_RS17045	COG1320	monovalent cation:proton antiporter activity
AC2117_RS17050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AC2117_RS17060	COG0195	Participates in both transcription termination and antitermination
AC2117_RS17105	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AC2117_RS17110	COG0237	dephospho-CoA kinase activity
AC2117_RS17120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC2117_RS17135	COG0497	DNA recombination
AC2117_RS17145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AC2117_RS17180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AC2117_RS17180	COG2169	Transcriptional regulator
AC2117_RS17185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC2117_RS17255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AC2117_RS17270	COG0326	Molecular chaperone. Has ATPase activity
AC2117_RS17285	COG2056	Na+-H+ antiporter family
AC2117_RS17290	COG0596	Alpha beta hydrolase
AC2117_RS17320	COG0222	ribosome binding
AC2117_RS17325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AC2117_RS17355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC2117_RS17385	COG0546	phosphoglycolate phosphatase activity
AC2117_RS17390	COG1716	ATPase activity
AC2117_RS17435	COG0181	hydroxymethylbilane synthase activity
AC2117_RS17445	COG3275	phosphorelay sensor kinase activity
AC2117_RS17465	COG1538	Outer membrane efflux protein
AC2117_RS17470	COG0697	spore germination
AC2117_RS17495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AC2117_RS17500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC2117_RS17505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC2117_RS17510	COG0772	Belongs to the SEDS family
AC2117_RS17535	COG4974	Belongs to the 'phage' integrase family
AC2117_RS17540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC2117_RS17550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AC2117_RS17560	COG2197	response regulator
AC2117_RS17575	COG0793	Belongs to the peptidase S41A family
AC2117_RS17580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AC2117_RS17585	COG0795	lipopolysaccharide-transporting ATPase activity
AC2117_RS17625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC2117_RS17625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC2117_RS17635	COG0004	ammonium transporteR
AC2117_RS17640	COG0347	Belongs to the P(II) protein family
AC2117_RS17650	COG0606	chelatase, subunit chli
AC2117_RS17655	COG0431	NADPH-dependent FMN reductase
AC2117_RS17670	COG0235	Class ii aldolase
AC2117_RS17675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC2117_RS17695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AC2117_RS17710	COG0318	PFAM AMP-dependent synthetase and ligase
AC2117_RS17720	COG0477	Major facilitator Superfamily
AC2117_RS17725	COG2860	membrane
AC2117_RS17730	COG3012	SEC-C Motif Domain Protein
AC2117_RS17735	COG1253	flavin adenine dinucleotide binding
AC2117_RS17745	COG2814	Major facilitator Superfamily
AC2117_RS17755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AC2117_RS17790	COG0655	NAD(P)H dehydrogenase (quinone) activity
AC2117_RS17805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AC2117_RS17840	COG1309	transcriptional regulator
AC2117_RS17875	COG0758	DNA mediated transformation
AC2117_RS17885	COG0697	spore germination
AC2117_RS17890	COG1309	transcriptional regulator
AC2117_RS17905	COG0386	Belongs to the glutathione peroxidase family
AC2117_RS17925	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AC2117_RS17975	COG1121	(ABC) transporter
AC2117_RS17980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AC2117_RS17990	COG2837	iron assimilation
AC2117_RS17995	COG0281	malic enzyme
AC2117_RS18040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC2117_RS18040	COG0519	Catalyzes the synthesis of GMP from XMP
AC2117_RS18045	COG4399	Belongs to the UPF0754 family
AC2117_RS18050	COG2259	Doxx family
AC2117_RS18055	COG0586	Pfam SNARE associated Golgi protein
AC2117_RS18070	COG1192	Involved in chromosome partitioning
AC2117_RS18080	COG0271	Belongs to the BolA IbaG family
AC2117_RS18100	COG2267	carboxylic ester hydrolase activity
AC2117_RS18120	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
AC2117_RS18120	COG0300	oxidoreductase activity
AC2117_RS18120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC2117_RS18120	COG3321	synthase
AC2117_RS18125	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS18135	COG2197	response regulator
AC2117_RS18145	COG3916	Acyl-homoserine-lactone synthase
AC2117_RS18150	COG0477	Major facilitator Superfamily
AC2117_RS18155	COG1024	Enoyl-CoA hydratase
AC2117_RS18160	COG1024	Enoyl-CoA hydratase
AC2117_RS18165	COG1960	acyl-CoA dehydrogenase activity
AC2117_RS18170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC2117_RS18190	COG1113	amino acid transport
AC2117_RS18195	COG1113	amino acid transport
AC2117_RS18200	COG0251	oxidation-reduction process
AC2117_RS18240	COG0564	pseudouridine synthase activity
AC2117_RS18290	COG2801	Transposase and inactivated derivatives
AC2117_RS18330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AC2117_RS18345	COG1802	Transcriptional regulator
AC2117_RS18350	COG1448	Aminotransferase
AC2117_RS18355	COG0277	FAD linked oxidase domain protein
AC2117_RS18365	COG2186	Transcriptional regulator
AC2117_RS18375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC2117_RS18380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AC2117_RS18395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AC2117_RS18405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AC2117_RS18415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AC2117_RS18455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC2117_RS18460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AC2117_RS18465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC2117_RS18470	COG1596	polysaccharide export
AC2117_RS18495	COG0728	peptidoglycan biosynthetic process
AC2117_RS18500	COG3023	N-Acetylmuramoyl-L-alanine amidase
AC2117_RS18555	COG0546	phosphoglycolate phosphatase activity
AC2117_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
AC2117_RS18575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AC2117_RS18575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AC2117_RS18580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AC2117_RS18585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AC2117_RS18590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC2117_RS18595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC2117_RS18600	COG1116	anion transmembrane transporter activity
AC2117_RS18605	COG1309	transcriptional regulator
AC2117_RS18610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AC2117_RS18620	COG0196	riboflavin kinase activity
AC2117_RS18625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AC2117_RS18635	COG1047	Peptidyl-prolyl cis-trans
AC2117_RS18675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AC2117_RS18680	COG0657	acetylesterase activity
AC2117_RS18730	COG2951	lytic endotransglycosylase activity
AC2117_RS18735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AC2117_RS18750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC2117_RS18760	COG0671	phosphoesterase, PA-phosphatase related
AC2117_RS18765	COG0861	Integral membrane protein TerC family
AC2117_RS18775	COG0402	S-adenosylhomocysteine deaminase activity
AC2117_RS18790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC2117_RS18795	COG1230	cation diffusion facilitator family transporter
AC2117_RS18810	COG0706	membrane insertase activity