locus-tag	class	description
CDG60_RS00015	COG0488	(ABC) transporter
CDG60_RS00020	COG3173	Aminoglycoside phosphotransferase
CDG60_RS00030	COG2801	Transposase and inactivated derivatives
CDG60_RS00190	COG0741	lytic transglycosylase activity
CDG60_RS00190	COG1196	nuclear chromosome segregation
CDG60_RS00190	COG0739	heme binding
CDG60_RS00250	COG1192	Involved in chromosome partitioning
CDG60_RS00310	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS00330	COG0673	inositol 2-dehydrogenase activity
CDG60_RS00335	COG1324	tolerance protein
CDG60_RS00365	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS00385	COG1525	nuclease
CDG60_RS00410	COG0739	heme binding
CDG60_RS00410	COG0741	lytic transglycosylase activity
CDG60_RS00410	COG1196	nuclear chromosome segregation
CDG60_RS00435	COG1475	DNA binding
CDG60_RS00440	COG1192	Involved in chromosome partitioning
CDG60_RS00475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG60_RS00490	COG1570	exodeoxyribonuclease VII activity
CDG60_RS00510	COG3657	addiction module killer protein
CDG60_RS00515	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG60_RS00525	COG2801	Transposase and inactivated derivatives
CDG60_RS00545	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS00555	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS00605	COG2801	Transposase and inactivated derivatives
CDG60_RS00615	COG0745	RESPONSE REGULATOR receiver
CDG60_RS00620	COG5002	protein histidine kinase activity
CDG60_RS00630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG60_RS00650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDG60_RS00725	COG1660	Displays ATPase and GTPase activities
CDG60_RS00745	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG60_RS00750	COG0592	DNA-directed DNA polymerase activity
CDG60_RS00760	COG0187	DNA topoisomerase II activity
CDG60_RS00770	COG0488	(ABC) transporter
CDG60_RS00795	COG0316	Belongs to the HesB IscA family
CDG60_RS00800	COG0596	Alpha beta hydrolase
CDG60_RS00805	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG60_RS00810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG60_RS00815	COG4521	taurine ABC transporter
CDG60_RS00820	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDG60_RS00825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG60_RS00830	COG2175	clavaminate synthase activity
CDG60_RS00840	COG0737	Belongs to the 5'-nucleotidase family
CDG60_RS00875	COG2814	Major facilitator Superfamily
CDG60_RS00900	COG1047	Peptidyl-prolyl cis-trans
CDG60_RS00905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDG60_RS00910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG60_RS00915	COG0196	riboflavin kinase activity
CDG60_RS00930	COG1309	transcriptional regulator
CDG60_RS00935	COG1116	anion transmembrane transporter activity
CDG60_RS00940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG60_RS00945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG60_RS00950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG60_RS00955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG60_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS00985	COG0546	phosphoglycolate phosphatase activity
CDG60_RS00990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG60_RS01005	COG1017	nitric oxide dioxygenase activity
CDG60_RS01005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG60_RS01015	COG1309	transcriptional regulator
CDG60_RS01065	COG1596	polysaccharide export
CDG60_RS01070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDG60_RS01115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG60_RS01125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG60_RS01135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG60_RS01150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG60_RS01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG60_RS01200	COG0768	penicillin binding
CDG60_RS01205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDG60_RS01210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDG60_RS01215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG60_RS01215	COG4451	ribulose bisphosphate carboxylase, small
CDG60_RS01220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG60_RS01230	COG0735	belongs to the Fur family
CDG60_RS01235	COG0215	cysteine-tRNA ligase activity
CDG60_RS01250	COG0523	cobalamin synthesis protein
CDG60_RS01280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDG60_RS01310	COG1294	oxidase, subunit
CDG60_RS01315	COG1271	oxidase subunit
CDG60_RS01340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG60_RS01350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDG60_RS01380	COG0271	Belongs to the BolA IbaG family
CDG60_RS01390	COG1192	Involved in chromosome partitioning
CDG60_RS01405	COG0586	Pfam SNARE associated Golgi protein
CDG60_RS01410	COG2259	Doxx family
CDG60_RS01415	COG0519	Catalyzes the synthesis of GMP from XMP
CDG60_RS01415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG60_RS01420	COG1715	Restriction endonuclease
CDG60_RS01455	COG2267	carboxylic ester hydrolase activity
CDG60_RS01465	COG0697	spore germination
CDG60_RS01480	COG0281	malic enzyme
CDG60_RS01500	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS01515	COG2837	iron assimilation
CDG60_RS01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG60_RS01535	COG1121	(ABC) transporter
CDG60_RS01585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG60_RS01620	COG2072	flavoprotein involved in K transport
CDG60_RS01625	COG4221	oxidoreductase activity
CDG60_RS01640	COG0386	Belongs to the glutathione peroxidase family
CDG60_RS01655	COG1309	transcriptional regulator
CDG60_RS01660	COG0697	spore germination
CDG60_RS01670	COG0758	DNA mediated transformation
CDG60_RS01705	COG1309	transcriptional regulator
CDG60_RS01760	COG2814	Major facilitator Superfamily
CDG60_RS01800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG60_RS01805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDG60_RS01835	COG1253	flavin adenine dinucleotide binding
CDG60_RS01860	COG2860	membrane
CDG60_RS01865	COG0477	Major facilitator Superfamily
CDG60_RS01885	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_RS01900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG60_RS01925	COG0606	chelatase, subunit chli
CDG60_RS01935	COG0347	Belongs to the P(II) protein family
CDG60_RS01940	COG0004	ammonium transporteR
CDG60_RS01950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG60_RS01950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG60_RS01965	COG0586	Pfam SNARE associated Golgi protein
CDG60_RS01990	COG0795	lipopolysaccharide-transporting ATPase activity
CDG60_RS01995	COG0795	lipopolysaccharide-transporting ATPase activity
CDG60_RS02000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDG60_RS02005	COG0793	Belongs to the peptidase S41A family
CDG60_RS02020	COG2197	response regulator
CDG60_RS02025	COG1686	Belongs to the peptidase S11 family
CDG60_RS02030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG60_RS02040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG60_RS02045	COG4974	Belongs to the 'phage' integrase family
CDG60_RS02070	COG0772	Belongs to the SEDS family
CDG60_RS02080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG60_RS02085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDG60_RS02090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDG60_RS02095	COG0494	nUDIX hydrolase
CDG60_RS02100	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDG60_RS02110	COG1538	Outer membrane efflux protein
CDG60_RS02130	COG3275	phosphorelay sensor kinase activity
CDG60_RS02140	COG0181	hydroxymethylbilane synthase activity
CDG60_RS02230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDG60_RS02245	COG0081	regulation of translation
CDG60_RS02250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDG60_RS02260	COG0085	RNA polymerase activity
CDG60_RS02285	COG2056	Na+-H+ antiporter family
CDG60_RS02305	COG0326	Molecular chaperone. Has ATPase activity
CDG60_RS02330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG60_RS02355	COG0183	Belongs to the thiolase family
CDG60_RS02410	COG1132	(ABC) transporter
CDG60_RS02420	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG60_RS02430	COG1289	transmembrane transporter activity
CDG60_RS02450	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDG60_RS02460	COG0497	DNA recombination
CDG60_RS02470	COG3123	guanosine phosphorylase activity
CDG60_RS02475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG60_RS02485	COG0237	dephospho-CoA kinase activity
CDG60_RS02540	COG0195	Participates in both transcription termination and antitermination
CDG60_RS02550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG60_RS02555	COG1320	monovalent cation:proton antiporter activity
CDG60_RS02560	COG2212	antiporter activity
CDG60_RS02565	COG1863	multisubunit Na H antiporter MnhE subunit
CDG60_RS02570	COG0651	ATP synthesis coupled electron transport
CDG60_RS02575	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG60_RS02580	COG2111	Na H antiporter
CDG60_RS02580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG60_RS02595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG60_RS02620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG60_RS02630	COG2226	methyltransferase
CDG60_RS02650	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDG60_RS02655	COG1074	ATP-dependent DNA helicase activity
CDG60_RS02660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG60_RS02665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG60_RS02675	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG60_RS02680	COG0598	Magnesium transport protein CorA
CDG60_RS02715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDG60_RS02725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDG60_RS02755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDG60_RS02760	COG4535	Mg2 and Co2 transporter CorC
CDG60_RS02770	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CDG60_RS02770	COG0644	oxidoreductase
CDG60_RS02780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG60_RS02795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG60_RS02800	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDG60_RS02810	COG0493	'glutamate synthase
CDG60_RS02850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDG60_RS02880	COG0752	glycyl-tRNA synthetase alpha subunit
CDG60_RS02895	COG0517	IMP dehydrogenase activity
CDG60_RS02895	COG0617	tRNA 3'-terminal CCA addition
CDG60_RS02895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDG60_RS02900	COG1983	PspC domain protein
CDG60_RS02930	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_RS02935	COG1530	ribonuclease E activity
CDG60_RS02945	COG0564	pseudouridine synthase activity
CDG60_RS02950	COG0546	phosphoglycolate phosphatase activity
CDG60_RS02955	COG3971	2-oxopent-4-enoate hydratase activity
CDG60_RS02960	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDG60_RS02985	COG0583	DNA-binding transcription factor activity
CDG60_RS02990	COG4638	Rieske (2fe-2S)
CDG60_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS03010	COG3384	dioxygenase
CDG60_RS03015	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG60_RS03040	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CDG60_RS03075	COG2801	Transposase and inactivated derivatives
CDG60_RS03085	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS03125	COG0583	DNA-binding transcription factor activity
CDG60_RS03145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG60_RS03160	COG0473	3-isopropylmalate dehydrogenase activity
CDG60_RS03180	COG0101	tRNA pseudouridine synthase activity
CDG60_RS03220	COG1560	Kdo2-lipid A biosynthetic process
CDG60_RS03225	COG0488	(ABC) transporter
CDG60_RS03230	COG2900	Belongs to the SlyX family
CDG60_RS03240	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS03245	COG1733	regulation of RNA biosynthetic process
CDG60_RS03260	COG2816	NAD+ diphosphatase activity
CDG60_RS03280	COG1929	Belongs to the glycerate kinase type-1 family
CDG60_RS03285	COG0210	DNA helicase
CDG60_RS03290	COG0724	RNA recognition motif
CDG60_RS03310	COG4651	solute:proton antiporter activity
CDG60_RS03310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG60_RS03335	COG0788	formyltetrahydrofolate deformylase activity
CDG60_RS03365	COG1295	ribonuclease BN
CDG60_RS03395	COG0793	Belongs to the peptidase S41A family
CDG60_RS03405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG60_RS03420	COG0084	hydrolase, TatD family'
CDG60_RS03435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDG60_RS03440	COG4589	Belongs to the CDS family
CDG60_RS03460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG60_RS03575	COG0556	nucleotide-excision repair
CDG60_RS03595	COG2814	Major facilitator Superfamily
CDG60_RS03640	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS03655	COG0004	ammonium transporteR
CDG60_RS03665	COG3622	Belongs to the hyi family
CDG60_RS03670	COG2084	Dehydrogenase
CDG60_RS03675	COG1024	Enoyl-CoA hydratase
CDG60_RS03680	COG0784	Response regulator, receiver
CDG60_RS03680	COG2205	protein histidine kinase activity
CDG60_RS03680	COG5002	protein histidine kinase activity
CDG60_RS03700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG60_RS03720	COG1862	Preprotein translocase
CDG60_RS03730	COG1704	LemA family
CDG60_RS03740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDG60_RS03750	COG2205	protein histidine kinase activity
CDG60_RS03750	COG0784	Response regulator, receiver
CDG60_RS03755	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG60_RS03780	COG0438	transferase activity, transferring glycosyl groups
CDG60_RS03805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDG60_RS03830	COG1216	Glycosyl transferase, family 2
CDG60_RS03830	COG0463	Glycosyl transferase, family 2
CDG60_RS03850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG60_RS03900	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS03905	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS03920	COG2205	protein histidine kinase activity
CDG60_RS03925	COG0745	RESPONSE REGULATOR receiver
CDG60_RS03930	COG2315	Protein conserved in bacteria
CDG60_RS03970	COG2096	Adenosyltransferase
CDG60_RS03975	COG4206	TonB-dependent receptor
CDG60_RS04005	COG3083	sulfuric ester hydrolase activity
CDG60_RS04035	COG0285	dihydrofolate synthase activity
CDG60_RS04055	COG0450	alkyl hydroperoxide reductase
CDG60_RS04070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG60_RS04075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG60_RS04105	COG2199	diguanylate cyclase activity
CDG60_RS04170	COG2969	positive regulation of protein catabolic process
CDG60_RS04175	COG0625	glutathione transferase activity
CDG60_RS04180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG60_RS04185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG60_RS04190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDG60_RS04195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG60_RS04200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG60_RS04230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG60_RS04240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG60_RS04245	COG1408	metallophosphoesterase
CDG60_RS04255	COG0477	Major facilitator Superfamily
CDG60_RS04260	COG1272	protein, Hemolysin III
CDG60_RS04275	COG1011	Hydrolase
CDG60_RS04290	COG1522	sequence-specific DNA binding
CDG60_RS04295	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG60_RS04295	COG1024	Enoyl-CoA hydratase
CDG60_RS04300	COG0183	Belongs to the thiolase family
CDG60_RS04305	COG2207	Transcriptional regulator
CDG60_RS04310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG60_RS04325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG60_RS04355	COG0183	Belongs to the thiolase family
CDG60_RS04375	COG0494	nUDIX hydrolase
CDG60_RS04385	COG1214	PFAM Peptidase M22, glycoprotease
CDG60_RS04390	COG1968	undecaprenyl-diphosphatase activity
CDG60_RS04410	COG4269	membrane
CDG60_RS04420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDG60_RS04430	COG2132	Multicopper oxidase
CDG60_RS04455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG60_RS04470	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_RS04470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG60_RS04470	COG0351	phosphomethylpyrimidine kinase
CDG60_RS04495	COG0251	oxidation-reduction process
CDG60_RS04500	COG1113	amino acid transport
CDG60_RS04510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG60_RS04520	COG1981	membrane
CDG60_RS04535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDG60_RS04560	COG0456	acetyltransferase
CDG60_RS04570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG60_RS04575	COG0492	ferredoxin-NADP+ reductase activity
CDG60_RS04580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDG60_RS04580	COG1674	ftsk spoiiie
CDG60_RS04595	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDG60_RS04600	COG2894	cell division
CDG60_RS04615	COG0204	Acyl-transferase
CDG60_RS04620	COG2885	chlorophyll binding
CDG60_RS04625	COG0210	DNA helicase
CDG60_RS04630	COG0756	dUTP diphosphatase activity
CDG60_RS04635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG60_RS04640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG60_RS04650	COG0121	glutamine amidotransferase
CDG60_RS04670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG60_RS04675	COG0735	belongs to the Fur family
CDG60_RS04715	COG0420	3'-5' exonuclease activity
CDG60_RS04750	COG0564	pseudouridine synthase activity
CDG60_RS04755	COG0456	acetyltransferase
CDG60_RS04770	COG3189	MarR family transcriptional regulator
CDG60_RS04775	COG2824	Alkylphosphonate utilization operon protein PhnA
CDG60_RS04785	COG3422	double-strand break repair
CDG60_RS04810	COG5342	invasion associated locus B
CDG60_RS04830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDG60_RS04855	COG0730	response to heat
CDG60_RS04865	COG1196	nuclear chromosome segregation
CDG60_RS04875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG60_RS04900	COG2193	ferroxidase activity
CDG60_RS04905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG60_RS04910	COG2267	carboxylic ester hydrolase activity
CDG60_RS04925	COG4106	trans-aconitate 2-methyltransferase activity
CDG60_RS04950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG60_RS04955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG60_RS04970	COG0009	L-threonylcarbamoyladenylate synthase
CDG60_RS04975	COG3101	peptidyl-lysine hydroxylation
CDG60_RS04980	COG1399	metal-binding, possibly nucleic acid-binding protein
CDG60_RS04995	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS05005	COG1652	LysM domain
CDG60_RS05065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG60_RS05080	COG0745	RESPONSE REGULATOR receiver
CDG60_RS05085	COG2205	protein histidine kinase activity
CDG60_RS05090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG60_RS05105	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG60_RS05130	COG0745	RESPONSE REGULATOR receiver
CDG60_RS05150	COG0004	ammonium transporteR
CDG60_RS05160	COG1126	abc transporter atp-binding protein
CDG60_RS05165	COG0765	amino acid transport
CDG60_RS05170	COG0765	amino acid transport
CDG60_RS05185	COG2852	Protein conserved in bacteria
CDG60_RS05210	COG0525	valine-tRNA ligase activity
CDG60_RS05220	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS05235	COG0393	Putative heavy-metal-binding
CDG60_RS05250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG60_RS05255	COG0671	phosphoesterase, PA-phosphatase related
CDG60_RS05270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDG60_RS05280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDG60_RS05295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDG60_RS05300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG60_RS05300	COG1648	precorrin-2 dehydrogenase activity
CDG60_RS05305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG60_RS05315	COG0531	amino acid
CDG60_RS05335	COG0321	lipoyl(octanoyl) transferase activity
CDG60_RS05345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDG60_RS05365	COG0586	Pfam SNARE associated Golgi protein
CDG60_RS05385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG60_RS05415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDG60_RS05445	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDG60_RS05460	COG0358	DNA primase activity
CDG60_RS05470	COG0564	pseudouridine synthase activity
CDG60_RS05505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDG60_RS05510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG60_RS05545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG60_RS05545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG60_RS05580	COG2009	succinate dehydrogenase
CDG60_RS05585	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDG60_RS05590	COG1053	succinate dehydrogenase
CDG60_RS05595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG60_RS05610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG60_RS05620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDG60_RS05625	COG2268	Band 7 protein
CDG60_RS05630	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG60_RS05640	COG2354	Protein conserved in bacteria
CDG60_RS05645	COG2321	neutral zinc metallopeptidase
CDG60_RS05700	COG0457	Tetratricopeptide repeat
CDG60_RS05725	COG0110	maltose O-acetyltransferase activity
CDG60_RS05730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDG60_RS05740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDG60_RS05745	COG0505	Belongs to the CarA family
CDG60_RS05765	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDG60_RS05770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG60_RS05775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG60_RS05820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDG60_RS05835	COG0477	Major facilitator Superfamily
CDG60_RS05850	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CDG60_RS05855	COG1597	lipid kinase activity
CDG60_RS05870	COG0459	protein refolding
CDG60_RS05875	COG5295	Hep Hag repeat protein
CDG60_RS05890	COG0584	glycerophosphoryl diester phosphodiesterase
CDG60_RS05895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG60_RS05900	COG2239	Acts as a magnesium transporter
CDG60_RS05915	COG0501	Belongs to the peptidase M48B family
CDG60_RS05920	COG0741	lytic transglycosylase activity
CDG60_RS05920	COG0739	heme binding
CDG60_RS05920	COG1196	nuclear chromosome segregation
CDG60_RS05925	COG0037	tRNA processing
CDG60_RS05940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG60_RS05975	COG0006	proline dipeptidase activity
CDG60_RS05985	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CDG60_RS06000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG60_RS06005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG60_RS06045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG60_RS06050	COG0741	lytic transglycosylase activity
CDG60_RS06050	COG1388	LysM domain
CDG60_RS06060	COG4174	ABC transporter (Permease)
CDG60_RS06065	COG4239	(ABC) transporter, permease
CDG60_RS06070	COG4172	Belongs to the ABC transporter superfamily
CDG60_RS06095	COG0281	malic enzyme
CDG60_RS06095	COG0280	phosphate acetyltransferase
CDG60_RS06100	COG3300	MHYT domain
CDG60_RS06100	COG5001	Diguanylate cyclase
CDG60_RS06105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG60_RS06115	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG60_RS06155	COG0582	viral genome integration into host DNA
CDG60_RS06210	COG0833	amino acid
CDG60_RS06220	COG0833	amino acid
CDG60_RS06225	COG4771	TonB-dependent receptor
CDG60_RS06235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG60_RS06240	COG0418	dihydroorotase activity
CDG60_RS06245	COG3706	GGDEF domain
CDG60_RS06250	COG5001	Diguanylate cyclase
CDG60_RS06250	COG3706	GGDEF domain
CDG60_RS06250	COG2203	Gaf domain
CDG60_RS06250	COG4251	negative regulation of phosphorylation
CDG60_RS06260	COG0583	DNA-binding transcription factor activity
CDG60_RS06265	COG0697	spore germination
CDG60_RS06280	COG2186	Transcriptional regulator
CDG60_RS06290	COG0277	FAD linked oxidase domain protein
CDG60_RS06300	COG1902	pentaerythritol trinitrate reductase activity
CDG60_RS06300	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG60_RS06335	COG4206	TonB-dependent receptor
CDG60_RS06335	COG1629	transport
CDG60_RS06350	COG1785	Belongs to the alkaline phosphatase family
CDG60_RS06355	COG1785	Belongs to the alkaline phosphatase family
CDG60_RS06430	COG0235	Class ii aldolase
CDG60_RS06445	COG1115	amino acid carrier protein
CDG60_RS06450	COG1113	amino acid transport
CDG60_RS06460	COG0019	diaminopimelate decarboxylase activity
CDG60_RS06470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDG60_RS06520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG60_RS06540	COG1671	Belongs to the UPF0178 family
CDG60_RS06555	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDG60_RS06560	COG1136	(ABC) transporter
CDG60_RS06565	COG0658	competence protein
CDG60_RS06565	COG2333	competence protein COMEC
CDG60_RS06585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDG60_RS06590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDG60_RS06595	COG0628	permease
CDG60_RS06600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG60_RS06630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG60_RS06650	COG0823	Involved in the tonB-independent uptake of proteins
CDG60_RS06670	COG0824	Thioesterase
CDG60_RS06680	COG0583	DNA-binding transcription factor activity
CDG60_RS06685	COG0473	3-isopropylmalate dehydrogenase activity
CDG60_RS06720	COG1454	alcohol dehydrogenase
CDG60_RS06730	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_RS06740	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG60_RS06740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG60_RS06755	COG0583	DNA-binding transcription factor activity
CDG60_RS06770	COG1024	Enoyl-CoA hydratase
CDG60_RS06775	COG1051	belongs to the nudix hydrolase family
CDG60_RS06775	COG1056	cytidyltransferase-related domain
CDG60_RS06790	COG0583	DNA-binding transcription factor activity
CDG60_RS06800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG60_RS06810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDG60_RS06815	COG0602	queuosine metabolic process
CDG60_RS06835	COG0583	DNA-binding transcription factor activity
CDG60_RS06840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDG60_RS06845	COG4208	sulfate ABC transporter
CDG60_RS06860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG60_RS06865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDG60_RS06870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDG60_RS06885	COG2207	Transcriptional regulator
CDG60_RS06910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG60_RS06925	COG0681	Belongs to the peptidase S26 family
CDG60_RS06935	COG0571	ribonuclease III activity
CDG60_RS06940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG60_RS06950	COG1381	Involved in DNA repair and RecF pathway recombination
CDG60_RS06955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDG60_RS07000	COG0436	Aminotransferase
CDG60_RS07020	COG0556	nucleotide-excision repair
CDG60_RS07055	COG1733	regulation of RNA biosynthetic process
CDG60_RS07065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDG60_RS07075	COG0671	phosphoesterase, PA-phosphatase related
CDG60_RS07085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG60_RS07090	COG0076	glutamate decarboxylase activity
CDG60_RS07105	COG0573	inorganic phosphate transmembrane transporter activity
CDG60_RS07115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG60_RS07125	COG0616	signal peptide processing
CDG60_RS07150	COG2915	High frequency lysogenization protein hflD homolog
CDG60_RS07155	COG0482	sulfurtransferase activity
CDG60_RS07165	COG2819	hydrolase of the alpha beta superfamily
CDG60_RS07180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG60_RS07185	COG1686	Belongs to the peptidase S11 family
CDG60_RS07210	COG0583	DNA-binding transcription factor activity
CDG60_RS07215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG60_RS07220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG60_RS07225	COG1067	ATP-dependent peptidase activity
CDG60_RS07230	COG2211	Major facilitator Superfamily
CDG60_RS07260	COG1509	lysine 2,3-aminomutase activity
CDG60_RS07265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG60_RS07270	COG1966	Carbon starvation protein
CDG60_RS07275	COG2879	small protein
CDG60_RS07280	COG0714	Associated with various cellular activities
CDG60_RS07310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDG60_RS07315	COG1845	cytochrome c oxidase, subunit III
CDG60_RS07320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG60_RS07325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG60_RS07340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDG60_RS07355	COG4682	membrane
CDG60_RS07360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG60_RS07380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDG60_RS07385	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG60_RS07405	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS07410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG60_RS07425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDG60_RS07430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG60_RS07450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG60_RS07455	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDG60_RS07465	COG2205	protein histidine kinase activity
CDG60_RS07470	COG0745	RESPONSE REGULATOR receiver
CDG60_RS07480	COG0477	Major facilitator Superfamily
CDG60_RS07485	COG0729	surface antigen
CDG60_RS07515	COG0288	reversible hydration of carbon dioxide
CDG60_RS07595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG60_RS07610	COG1113	amino acid transport
CDG60_RS07635	COG0308	aminopeptidase N
CDG60_RS07645	COG0589	response to stress
CDG60_RS07650	COG0589	response to stress
CDG60_RS07665	COG3135	benzoate transporter
CDG60_RS07675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG60_RS07680	COG0583	DNA-binding transcription factor activity
CDG60_RS07700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG60_RS07705	COG3850	Histidine kinase
CDG60_RS07710	COG0659	secondary active sulfate transmembrane transporter activity
CDG60_RS07715	COG0625	glutathione transferase activity
CDG60_RS07730	COG2363	Small membrane protein
CDG60_RS07745	COG1278	Cold shock
CDG60_RS07750	COG0513	Belongs to the DEAD box helicase family
CDG60_RS07760	COG0778	Nitroreductase
CDG60_RS07815	COG4783	chaperone-mediated protein folding
CDG60_RS07830	COG1610	YqeY-like protein
CDG60_RS07845	COG0307	riboflavin synthase, alpha
CDG60_RS07900	COG0069	glutamate synthase activity
CDG60_RS07910	COG4585	Histidine kinase
CDG60_RS07915	COG2850	peptidyl-arginine hydroxylation
CDG60_RS07925	COG0424	maF-like protein
CDG60_RS07950	COG0697	spore germination
CDG60_RS07965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_RS07975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG60_RS07985	COG0583	DNA-binding transcription factor activity
CDG60_RS07990	COG0667	Aldo Keto reductase
CDG60_RS08020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG60_RS08025	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG60_RS08025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG60_RS08025	COG0506	proline dehydrogenase activity
CDG60_RS08040	COG1027	Aspartate ammonia-lyase
CDG60_RS08050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDG60_RS08060	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS08070	COG0583	DNA-binding transcription factor activity
CDG60_RS08085	COG1902	pentaerythritol trinitrate reductase activity
CDG60_RS08085	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG60_RS08100	COG2814	Major facilitator Superfamily
CDG60_RS08105	COG0656	L-ascorbic acid biosynthetic process
CDG60_RS08110	COG0583	DNA-binding transcription factor activity
CDG60_RS08130	COG0148	phosphopyruvate hydratase activity
CDG60_RS08145	COG0772	Belongs to the SEDS family
CDG60_RS08175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG60_RS08180	COG0730	response to heat
CDG60_RS08185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_RS08190	COG2207	Transcriptional regulator
CDG60_RS08195	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG60_RS08200	COG2910	NAD(P)H-binding
CDG60_RS08205	COG0583	DNA-binding transcription factor activity
CDG60_RS08215	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS08280	COG2431	L-lysine efflux transmembrane transporter activity
CDG60_RS08295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDG60_RS08305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG60_RS08315	COG1253	flavin adenine dinucleotide binding
CDG60_RS08330	COG4890	Cyd operon protein YbgT
CDG60_RS08335	COG1294	oxidase, subunit
CDG60_RS08350	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG60_RS08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG60_RS08370	COG1051	belongs to the nudix hydrolase family
CDG60_RS08395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG60_RS08400	COG0569	domain protein
CDG60_RS08415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG60_RS08420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDG60_RS08440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG60_RS08445	COG0542	response to heat
CDG60_RS08490	COG0372	Belongs to the citrate synthase family
CDG60_RS08545	COG1396	sequence-specific DNA binding
CDG60_RS08600	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS08610	COG1278	Cold shock
CDG60_RS08660	COG1802	Transcriptional regulator
CDG60_RS08660	COG4626	Terminase
CDG60_RS08665	COG4695	Portal protein
CDG60_RS08805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG60_RS08820	COG2323	membrane
CDG60_RS08835	COG0582	viral genome integration into host DNA
CDG60_RS08840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG60_RS08860	COG2814	Major facilitator Superfamily
CDG60_RS08870	COG2199	diguanylate cyclase activity
CDG60_RS08880	COG0439	Biotin carboxylase
CDG60_RS08885	COG0511	ligase activity, forming carbon-carbon bonds
CDG60_RS08905	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDG60_RS08920	COG1346	cytolysis
CDG60_RS08930	COG0583	DNA-binding transcription factor activity
CDG60_RS08950	COG1840	ABC-type Fe3 transport system, periplasmic component
CDG60_RS08955	COG3842	ATPase activity
CDG60_RS08975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG60_RS08990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDG60_RS09000	COG0745	RESPONSE REGULATOR receiver
CDG60_RS09030	COG4206	TonB-dependent receptor
CDG60_RS09040	COG0596	Alpha beta hydrolase
CDG60_RS09045	COG4772	TonB-dependent receptor
CDG60_RS09125	COG0210	DNA helicase
CDG60_RS09130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG60_RS09175	COG0431	NADPH-dependent FMN reductase
CDG60_RS09180	COG1902	pentaerythritol trinitrate reductase activity
CDG60_RS09200	COG1741	Belongs to the pirin family
CDG60_RS09210	COG1944	ATP diphosphatase activity
CDG60_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS09240	COG0697	spore germination
CDG60_RS09250	COG0583	DNA-binding transcription factor activity
CDG60_RS09255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG60_RS09260	COG2937	Belongs to the GPAT DAPAT family
CDG60_RS09265	COG0640	Transcriptional regulator
CDG60_RS09285	COG3122	Protein conserved in bacteria
CDG60_RS09290	COG0668	transmembrane transport
CDG60_RS09295	COG1132	(ABC) transporter
CDG60_RS09300	COG2030	dehydratase
CDG60_RS09310	COG0509	glycine decarboxylation via glycine cleavage system
CDG60_RS09320	COG2814	Major facilitator Superfamily
CDG60_RS09330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG60_RS09335	COG1448	Aminotransferase
CDG60_RS09340	COG0488	(ABC) transporter
CDG60_RS09345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG60_RS09350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG60_RS09370	COG0697	spore germination
CDG60_RS09455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG60_RS09470	COG1294	oxidase, subunit
CDG60_RS09475	COG1271	oxidase subunit
CDG60_RS09520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG60_RS09560	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDG60_RS09730	COG5410	chromosome segregation
CDG60_RS09865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG60_RS09905	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CDG60_RS09915	COG0552	protein localization to endoplasmic reticulum
CDG60_RS09920	COG0612	Peptidase, M16
CDG60_RS09950	COG0516	GMP reductase activity
CDG60_RS09950	COG0517	IMP dehydrogenase activity
CDG60_RS09955	COG0133	tryptophan synthase activity
CDG60_RS09970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG60_RS09990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG60_RS10020	COG0537	adenosine 5'-monophosphoramidase activity
CDG60_RS10030	COG3753	Protein conserved in bacteria
CDG60_RS10045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG60_RS10075	COG0822	iron-sulfur transferase activity
CDG60_RS10080	COG0316	Belongs to the HesB IscA family
CDG60_RS10110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDG60_RS10125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG60_RS10130	COG0702	epimerase
CDG60_RS10135	COG0268	Binds directly to 16S ribosomal RNA
CDG60_RS10160	COG1011	Hydrolase
CDG60_RS10165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDG60_RS10170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDG60_RS10175	COG2137	regulation of response to DNA damage stimulus
CDG60_RS10190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_RS10195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG60_RS10200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_RS10210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG60_RS10225	COG0575	Belongs to the CDS family
CDG60_RS10230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG60_RS10250	COG3852	Histidine kinase
CDG60_RS10255	COG2204	response regulator
CDG60_RS10265	COG0583	DNA-binding transcription factor activity
CDG60_RS10270	COG0024	Methionine aminopeptidase
CDG60_RS10275	COG1114	Component of the transport system for branched-chain amino acids
CDG60_RS10285	COG0776	regulation of translation
CDG60_RS10315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDG60_RS10350	COG0084	hydrolase, TatD family'
CDG60_RS10370	COG1663	tetraacyldisaccharide 4'-kinase activity
CDG60_RS10375	COG1132	(ABC) transporter
CDG60_RS10385	COG0811	peptide transport
CDG60_RS10390	COG1475	DNA binding
CDG60_RS10395	COG1192	Involved in chromosome partitioning
CDG60_RS10405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDG60_RS10410	COG3178	'Phosphotransferase
CDG60_RS10420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG60_RS10425	COG1923	regulation of RNA biosynthetic process
CDG60_RS10435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDG60_RS10440	COG0802	atpase or kinase
CDG60_RS10460	COG1187	pseudouridine synthase activity
CDG60_RS10465	COG2707	UPF0756 membrane protein
CDG60_RS10490	COG0583	DNA-binding transcription factor activity
CDG60_RS10495	COG0786	glutamate:sodium symporter activity
CDG60_RS10500	COG2814	Major facilitator Superfamily
CDG60_RS10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG60_RS10510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG60_RS10520	COG1454	alcohol dehydrogenase
CDG60_RS10550	COG0583	DNA-binding transcription factor activity
CDG60_RS10570	COG1309	transcriptional regulator
CDG60_RS10575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG60_RS10575	COG0519	Catalyzes the synthesis of GMP from XMP
CDG60_RS10580	COG2353	YceI-like domain
CDG60_RS10600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDG60_RS10605	COG3706	GGDEF domain
CDG60_RS10610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG60_RS10655	COG1254	Belongs to the acylphosphatase family
CDG60_RS10660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDG60_RS10660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDG60_RS10665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDG60_RS10685	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_RS10700	COG1278	Cold shock
CDG60_RS10710	COG0204	Acyl-transferase
CDG60_RS10730	COG0012	GTP binding
CDG60_RS10750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDG60_RS10765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDG60_RS10780	COG0386	Belongs to the glutathione peroxidase family
CDG60_RS10785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG60_RS10790	COG0436	Aminotransferase
CDG60_RS10815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG60_RS10820	COG1454	alcohol dehydrogenase
CDG60_RS10825	COG0824	Thioesterase
CDG60_RS10835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDG60_RS10840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG60_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS10855	COG0183	Belongs to the thiolase family
CDG60_RS10880	COG2885	chlorophyll binding
CDG60_RS10890	COG0540	Belongs to the ATCase OTCase family
CDG60_RS10920	COG0542	response to heat
CDG60_RS10925	COG1045	serine acetyltransferase
CDG60_RS10935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG60_RS10940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDG60_RS10945	COG1765	OsmC-like protein
CDG60_RS10960	COG0667	Aldo Keto reductase
CDG60_RS10980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG60_RS11010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG60_RS11010	COG3008	intermembrane lipid transfer
CDG60_RS11015	COG2995	paraquat-inducible protein a
CDG60_RS11020	COG2995	paraquat-inducible protein a
CDG60_RS11030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDG60_RS11040	COG0183	Belongs to the thiolase family
CDG60_RS11050	COG0527	aspartate kinase activity
CDG60_RS11060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG60_RS11070	COG3038	cytochrome b561
CDG60_RS11080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG60_RS11085	COG2252	PERMEase
CDG60_RS11095	COG0360	Binds together with S18 to 16S ribosomal RNA
CDG60_RS11100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDG60_RS11135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG60_RS11145	COG1305	Transglutaminase-like
CDG60_RS11155	COG2308	Evidence 4 Homologs of previously reported genes of
CDG60_RS11165	COG2814	Major facilitator Superfamily
CDG60_RS11205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG60_RS11210	COG0138	bifunctional purine biosynthesis protein purh
CDG60_RS11215	COG0151	Belongs to the GarS family
CDG60_RS11235	COG1464	Belongs to the NlpA lipoprotein family
CDG60_RS11240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG60_RS11245	COG2011	ABC-type metal ion transport system permease component
CDG60_RS11285	COG2203	Gaf domain
CDG60_RS11285	COG2199	diguanylate cyclase activity
CDG60_RS11300	COG4638	Rieske (2fe-2S)
CDG60_RS11305	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDG60_RS11310	COG0543	2 iron, 2 sulfur cluster binding
CDG60_RS11310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG60_RS11330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS11355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDG60_RS11365	COG4122	O-methyltransferase activity
CDG60_RS11390	COG1132	(ABC) transporter
CDG60_RS11400	COG1137	ATPase activity
CDG60_RS11405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDG60_RS11415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDG60_RS11420	COG0517	IMP dehydrogenase activity
CDG60_RS11420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG60_RS11465	COG1203	CRISPR-associated helicase, Cas3
CDG60_RS11470	COG1518	maintenance of DNA repeat elements
CDG60_RS11495	COG0427	acetyl-CoA hydrolase
CDG60_RS11500	COG0183	Belongs to the thiolase family
CDG60_RS11505	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS11540	COG1643	Atp-dependent helicase
CDG60_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS11600	COG2391	methyltransferase activity
CDG60_RS11605	COG2070	2-Nitropropane dioxygenase
CDG60_RS11655	COG0564	pseudouridine synthase activity
CDG60_RS11675	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_RS11735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG60_RS11745	COG0612	Peptidase, M16
CDG60_RS11760	COG1823	symporter activity
CDG60_RS11765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_RS11790	COG0730	response to heat
CDG60_RS11795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_RS11820	COG1686	Belongs to the peptidase S11 family
CDG60_RS11825	COG1252	NADH dehydrogenase
CDG60_RS11840	COG0415	Belongs to the DNA photolyase family
CDG60_RS11855	COG3022	response to hydroperoxide
CDG60_RS11865	COG1301	dicarboxylic acid transport
CDG60_RS11870	COG4650	regulator
CDG60_RS11875	COG1690	Belongs to the RtcB family
CDG60_RS11890	COG0430	RNA-3'-phosphate cyclase activity
CDG60_RS11905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG60_RS11915	COG0693	protein deglycase activity
CDG60_RS11920	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS11925	COG1301	dicarboxylic acid transport
CDG60_RS11935	COG3139	Protein of unknown function (DUF1315)
CDG60_RS11940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG60_RS11945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG60_RS11955	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_RS11980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDG60_RS12000	COG1720	tRNA m6t6A37 methyltransferase activity
CDG60_RS12015	COG4993	Dehydrogenase
CDG60_RS12040	COG0798	PFAM Bile acid sodium symporter
CDG60_RS12050	COG0640	Transcriptional regulator
CDG60_RS12055	COG0826	peptidase U32
CDG60_RS12060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG60_RS12070	COG0583	DNA-binding transcription factor activity
CDG60_RS12075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDG60_RS12080	COG3634	alkyl hydroperoxide reductase activity
CDG60_RS12110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG60_RS12405	COG0582	viral genome integration into host DNA
CDG60_RS12415	COG1131	(ABC) transporter
CDG60_RS12420	COG0842	Transport permease protein
CDG60_RS12435	COG2951	lytic endotransglycosylase activity
CDG60_RS12480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDG60_RS12485	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG60_RS12540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG60_RS12545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG60_RS12560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDG60_RS12565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG60_RS12570	COG2885	chlorophyll binding
CDG60_RS12660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG60_RS12675	COG2234	aminopeptidase activity
CDG60_RS12680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDG60_RS12685	COG3384	dioxygenase
CDG60_RS12705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG60_RS12715	COG2878	Part of a membrane complex involved in electron transport
CDG60_RS12720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDG60_RS12745	COG0768	penicillin binding
CDG60_RS12750	COG0742	ribosomal rna small subunit methyltransferase
CDG60_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS12795	COG1253	flavin adenine dinucleotide binding
CDG60_RS12800	COG2851	Citrate transporter
CDG60_RS12830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG60_RS12835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG60_RS12840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG60_RS12910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG60_RS12955	COG0583	DNA-binding transcription factor activity
CDG60_RS12970	COG0174	glutamine synthetase
CDG60_RS12975	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG60_RS12980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG60_RS13005	COG0302	gtp cyclohydrolase
CDG60_RS13020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDG60_RS13050	COG3739	integral membrane protein
CDG60_RS13065	COG1741	Belongs to the pirin family
CDG60_RS13075	COG0019	diaminopimelate decarboxylase activity
CDG60_RS13085	COG3433	isochorismatase activity
CDG60_RS13085	COG1535	isochorismatase
CDG60_RS13090	COG1021	2,3-dihydroxybenzoate-AMP ligase
CDG60_RS13095	COG1169	isochorismate synthase
CDG60_RS13100	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS13115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDG60_RS13120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG60_RS13125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG60_RS13130	COG1120	ATPase activity
CDG60_RS13165	COG0175	sulfate reduction
CDG60_RS13190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDG60_RS13195	COG1773	rubredoxin
CDG60_RS13200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG60_RS13210	COG0583	DNA-binding transcription factor activity
CDG60_RS13230	COG0705	Rhomboid family
CDG60_RS13230	COG0457	Tetratricopeptide repeat
CDG60_RS13235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDG60_RS13240	COG4181	ATPase activity
CDG60_RS13265	COG0500	methyltransferase
CDG60_RS13270	COG4771	TonB-dependent receptor
CDG60_RS13290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDG60_RS13300	COG0306	phosphate transporter
CDG60_RS13315	COG2852	Protein conserved in bacteria
CDG60_RS13320	COG2223	nitrite transmembrane transporter activity
CDG60_RS13325	COG2207	Transcriptional regulator
CDG60_RS13330	COG0242	peptide deformylase activity
CDG60_RS13340	COG0477	Major facilitator Superfamily
CDG60_RS13360	COG1024	Enoyl-CoA hydratase
CDG60_RS13390	COG1215	transferase activity, transferring glycosyl groups
CDG60_RS13395	COG0726	polysaccharide deacetylase
CDG60_RS13395	COG1649	PFAM Uncharacterised BCR, COG1649
CDG60_RS13405	COG3706	GGDEF domain
CDG60_RS13405	COG4251	negative regulation of phosphorylation
CDG60_RS13405	COG5001	Diguanylate cyclase
CDG60_RS13405	COG2203	Gaf domain
CDG60_RS13415	COG4681	YaeQ
CDG60_RS13420	COG0523	cobalamin synthesis protein
CDG60_RS13450	COG2188	Transcriptional regulator
CDG60_RS13470	COG0583	DNA-binding transcription factor activity
CDG60_RS13475	COG2814	Major facilitator Superfamily
CDG60_RS13485	COG1607	acyl-coa hydrolase
CDG60_RS13495	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG60_RS13500	COG2059	Chromate
CDG60_RS13505	COG0786	glutamate:sodium symporter activity
CDG60_RS13520	COG2814	Major facilitator Superfamily
CDG60_RS13525	COG1289	transmembrane transporter activity
CDG60_RS13535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDG60_RS13595	COG2832	Protein of unknown function (DUF454)
CDG60_RS13610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG60_RS13620	COG0784	Response regulator, receiver
CDG60_RS13620	COG2198	Histidine kinase
CDG60_RS13620	COG0643	Histidine kinase
CDG60_RS13625	COG0840	transmembrane signaling receptor activity
CDG60_RS13660	COG0442	prolyl-tRNA aminoacylation
CDG60_RS13705	COG0489	protein tyrosine kinase activity
CDG60_RS13735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG60_RS13735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG60_RS13780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CDG60_RS13785	COG2081	HI0933 family
CDG60_RS13790	COG0668	transmembrane transport
CDG60_RS13805	COG0583	DNA-binding transcription factor activity
CDG60_RS13815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDG60_RS13825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_RS13830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG60_RS13835	COG0713	ATP synthesis coupled electron transport
CDG60_RS13845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_RS13860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDG60_RS13870	COG0649	NAD binding
CDG60_RS13870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_RS13880	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_RS13890	COG0142	geranyltranstransferase activity
CDG60_RS13895	COG2828	Protein conserved in bacteria
CDG60_RS13900	COG1113	amino acid transport
CDG60_RS13910	COG0582	viral genome integration into host DNA
CDG60_RS14000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG60_RS14005	COG1530	ribonuclease E activity
CDG60_RS14010	COG0424	maF-like protein
CDG60_RS14015	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CDG60_RS14020	COG1792	Involved in formation and maintenance of cell shape
CDG60_RS14025	COG1077	Cell shape determining protein MreB Mrl
CDG60_RS14030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG60_RS14040	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG60_RS14050	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS14075	COG0583	DNA-binding transcription factor activity
CDG60_RS14100	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDG60_RS14120	COG0270	DNA (cytosine-5-)-methyltransferase activity
CDG60_RS14140	COG0583	DNA-binding transcription factor activity
CDG60_RS14160	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_RS14170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG60_RS14180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_RS14200	COG0789	Transcriptional regulator
CDG60_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_RS14245	COG1454	alcohol dehydrogenase
CDG60_RS14250	COG0657	acetylesterase activity
CDG60_RS14265	COG2072	flavoprotein involved in K transport
CDG60_RS14270	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_RS14320	COG2871	sodium ion transport
CDG60_RS14330	COG3485	protocatechuate 3,4-dioxygenase
CDG60_RS14335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG60_RS14340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDG60_RS14345	COG0583	DNA-binding transcription factor activity
CDG60_RS14350	COG4948	Mandelate Racemase Muconate Lactonizing
CDG60_RS14355	COG4829	muconolactone delta-isomerase
CDG60_RS14360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG60_RS14365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG60_RS14370	COG0183	Belongs to the thiolase family
CDG60_RS14375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG60_RS14385	COG3177	Filamentation induced by cAMP protein fic
CDG60_RS14455	COG1802	Transcriptional regulator
CDG60_RS14460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG60_RS14465	COG3135	benzoate transporter
CDG60_RS14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG60_RS14480	COG0235	Class ii aldolase
CDG60_RS14485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG60_RS14500	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDG60_RS14510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG60_RS14580	COG0582	viral genome integration into host DNA
CDG60_RS14590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG60_RS14595	COG2814	Major facilitator Superfamily
CDG60_RS14600	COG1566	PFAM secretion protein HlyD family protein
CDG60_RS14605	COG2050	protein possibly involved in aromatic compounds catabolism
CDG60_RS14615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG60_RS14620	COG1090	epimerase
CDG60_RS14645	COG1487	ribonuclease activity
CDG60_RS14650	COG4456	Virulence-associated protein
CDG60_RS14670	COG0354	folic acid binding
CDG60_RS14690	COG1902	pentaerythritol trinitrate reductase activity
CDG60_RS14695	COG3659	wide pore channel activity
CDG60_RS14705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG60_RS14715	COG1970	mechanosensitive ion channel activity
CDG60_RS14725	COG1217	gtp-binding protein TYPA
CDG60_RS14730	COG2233	PERMEase
CDG60_RS14740	COG0833	amino acid
CDG60_RS14795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG60_RS14805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG60_RS14880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG60_RS14890	COG1764	response to oxidative stress
CDG60_RS14910	COG1196	nuclear chromosome segregation
CDG60_RS14910	COG3264	Mechanosensitive ion channel
CDG60_RS14940	COG0037	tRNA processing
CDG60_RS14975	COG0072	phenylalanine-tRNA ligase activity
CDG60_RS14980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDG60_RS15025	COG1238	metal cluster binding
CDG60_RS15035	COG0625	glutathione transferase activity
CDG60_RS15075	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_RS15090	COG1660	Displays ATPase and GTPase activities
CDG60_RS15105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDG60_RS15110	COG0617	tRNA 3'-terminal CCA addition
CDG60_RS15115	COG1555	photosystem II stabilization
CDG60_RS15120	COG3956	TIGRFAM MazG family protein
CDG60_RS15135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG60_RS15200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDG60_RS15210	COG0028	Belongs to the TPP enzyme family
CDG60_RS15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG60_RS15250	COG1136	(ABC) transporter
CDG60_RS15250	COG0577	efflux transmembrane transporter activity
CDG60_RS15255	COG1538	Outer membrane efflux protein
CDG60_RS15275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG60_RS15280	COG1162	GTPase activity
CDG60_RS15290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDG60_RS15310	COG3783	Cytochrome b(562)
CDG60_RS15315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDG60_RS15320	COG2003	Belongs to the UPF0758 family
CDG60_RS15325	COG3781	membrane
CDG60_RS15330	COG0613	PHP domain protein
CDG60_RS15340	COG2350	Protein conserved in bacteria
CDG60_RS15360	COG1666	GTP binding
CDG60_RS15375	COG1607	acyl-coa hydrolase
CDG60_RS15405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG60_RS15450	COG1183	phosphatidylcholine synthase activity
CDG60_RS15455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDG60_RS15490	COG0739	heme binding
CDG60_RS15490	COG0741	lytic transglycosylase activity
CDG60_RS15490	COG1196	nuclear chromosome segregation
CDG60_RS15495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDG60_RS15500	COG1702	phosphate starvation-inducible protein PhoH
CDG60_RS15540	COG2267	carboxylic ester hydrolase activity
CDG60_RS15550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDG60_RS15555	COG0857	belongs to the CobB CobQ family
CDG60_RS15555	COG0280	phosphate acetyltransferase
CDG60_RS15565	COG2226	methyltransferase
CDG60_RS15570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG60_RS15570	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG60_RS15590	COG0740	serine-type endopeptidase activity
CDG60_RS15600	COG4774	siderophore transport
CDG60_RS15605	COG4774	siderophore transport
CDG60_RS15620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG60_RS15630	COG2813	Specifically methylates the guanine in position
CDG60_RS15630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG60_RS15645	COG1063	alcohol dehydrogenase
CDG60_RS15710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDG60_RS15740	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG60_RS15775	COG0557	exoribonuclease II activity
CDG60_RS15790	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CDG60_RS15805	COG4753	response regulator
CDG60_RS15805	COG2207	Transcriptional regulator
CDG60_RS15810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG60_RS15815	COG0697	spore germination
CDG60_RS15845	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDG60_RS15850	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS15855	COG2072	flavoprotein involved in K transport
CDG60_RS15860	COG0203	ribosomal protein L17
CDG60_RS15865	COG0202	RNA polymerase activity
CDG60_RS15870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDG60_RS15905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG60_RS15915	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDG60_RS15920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG60_RS15930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDG60_RS15970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG60_RS15985	COG0088	Forms part of the polypeptide exit tunnel
CDG60_RS15995	COG0051	transcription antitermination factor activity, RNA binding
CDG60_RS16005	COG0626	cystathionine gamma-synthase activity
CDG60_RS16010	COG0433	COG0433 Predicted ATPase
CDG60_RS16045	COG1959	2 iron, 2 sulfur cluster binding
CDG60_RS16060	COG1301	dicarboxylic acid transport
CDG60_RS16065	COG1946	Acyl-CoA thioesterase
CDG60_RS16070	COG2937	Belongs to the GPAT DAPAT family
CDG60_RS16085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDG60_RS16095	COG1040	competence protein
CDG60_RS16100	COG0494	nUDIX hydrolase
CDG60_RS16110	COG0598	Magnesium transport protein CorA
CDG60_RS16125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG60_RS16130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG60_RS16135	COG1127	ABC transporter
CDG60_RS16140	COG0513	Belongs to the DEAD box helicase family
CDG60_RS16150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDG60_RS16155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG60_RS16160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG60_RS16170	COG0408	coproporphyrinogen oxidase activity
CDG60_RS16190	COG1960	acyl-CoA dehydrogenase activity
CDG60_RS16205	COG1215	transferase activity, transferring glycosyl groups
CDG60_RS16235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG60_RS16250	COG0534	Mate efflux family protein
CDG60_RS16260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG60_RS16265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG60_RS16285	COG2226	methyltransferase
CDG60_RS16300	COG1192	Involved in chromosome partitioning
CDG60_RS16305	COG0628	permease
CDG60_RS16315	COG1289	transmembrane transporter activity
CDG60_RS16320	COG2814	Major facilitator Superfamily
CDG60_RS16365	COG0277	FAD linked oxidase domain protein
CDG60_RS16375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG60_RS16380	COG5006	permease, DMT superfamily
CDG60_RS16400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG60_RS16405	COG5380	lipid catabolic process
CDG60_RS16410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDG60_RS16420	COG4969	Belongs to the N-Me-Phe pilin family
CDG60_RS16455	COG0335	large ribosomal subunit rRNA binding
CDG60_RS16465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG60_RS16470	COG0228	four-way junction DNA binding
CDG60_RS16545	COG0194	GDP metabolic process
CDG60_RS16550	COG1758	RNA polymerase activity
CDG60_RS16555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG60_RS16575	COG3307	-O-antigen
CDG60_RS16590	COG3307	-O-antigen
CDG60_RS16595	COG4969	Belongs to the N-Me-Phe pilin family
CDG60_RS16605	COG2161	toxin-antitoxin pair type II binding
CDG60_RS16615	COG2194	sulfuric ester hydrolase activity
CDG60_RS16705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDG60_RS16710	COG1704	LemA family
CDG60_RS16720	COG0493	'glutamate synthase
CDG60_RS16725	COG0069	glutamate synthase activity
CDG60_RS16725	COG0070	glutamate synthase
CDG60_RS16725	COG0067	glutamate synthase
CDG60_RS16775	COG2226	methyltransferase
CDG60_RS16780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDG60_RS16785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG60_RS16790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDG60_RS16800	COG3116	cell division
CDG60_RS16810	COG0456	acetyltransferase
CDG60_RS16815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG60_RS16835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG60_RS16885	COG0488	(ABC) transporter
CDG60_RS16890	COG2873	o-acetylhomoserine
CDG60_RS16895	COG4221	oxidoreductase activity
CDG60_RS16920	COG0427	acetyl-CoA hydrolase
CDG60_RS16975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG60_RS17000	COG1278	Cold shock
CDG60_RS17005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDG60_RS17040	COG3158	transport of potassium into the cell
CDG60_RS17065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG60_RS17075	COG1335	isochorismatase
CDG60_RS17120	COG2814	Major facilitator Superfamily
CDG60_RS17130	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_RS17130	COG0351	phosphomethylpyrimidine kinase
CDG60_RS17130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG60_RS17155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDG60_RS17175	COG2199	diguanylate cyclase activity
CDG60_RS17185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG60_RS17200	COG3162	membrane
CDG60_RS17205	COG0784	Response regulator, receiver
CDG60_RS17205	COG2205	protein histidine kinase activity
CDG60_RS17220	COG0431	NADPH-dependent FMN reductase
CDG60_RS17245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG60_RS17250	COG3152	Membrane
CDG60_RS17255	COG2755	lipolytic protein G-D-S-L family
CDG60_RS17255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDG60_RS17260	COG0668	transmembrane transport
CDG60_RS17265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG60_RS17270	COG1519	Transferase
CDG60_RS17280	COG1902	pentaerythritol trinitrate reductase activity
CDG60_RS17305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDG60_RS17335	COG0426	domain, Protein
CDG60_RS17335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_RS17340	COG2119	membrane
CDG60_RS17370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG60_RS17380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDG60_RS17390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG60_RS17400	COG0189	ligase activity
CDG60_RS17415	COG0708	Exodeoxyribonuclease III
CDG60_RS17435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDG60_RS17470	COG0456	acetyltransferase
CDG60_RS17495	COG3150	esterase
CDG60_RS17505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDG60_RS17510	COG2918	glutathione biosynthetic process
CDG60_RS17520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDG60_RS17530	COG2733	membrane
CDG60_RS17545	COG2801	Transposase and inactivated derivatives
CDG60_RS17565	COG0436	Aminotransferase
CDG60_RS17570	COG0534	Mate efflux family protein
CDG60_RS17605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDG60_RS17655	COG0385	Bile acid
CDG60_RS17660	COG1335	isochorismatase
CDG60_RS17665	COG2814	Major facilitator Superfamily
CDG60_RS17670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG60_RS17685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDG60_RS17690	COG5001	Diguanylate cyclase
CDG60_RS17695	COG1683	Conserved Protein
CDG60_RS17700	COG2983	Belongs to the UPF0260 family
CDG60_RS17705	COG5487	UPF0391 membrane protein
CDG60_RS17735	COG2818	Glycosylase
CDG60_RS17740	COG1064	alcohol dehydrogenase
CDG60_RS17745	COG0156	8-amino-7-oxononanoate synthase activity
CDG60_RS17770	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDG60_RS17790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG60_RS17800	COG2233	PERMEase
CDG60_RS17805	COG0583	DNA-binding transcription factor activity
CDG60_RS17815	COG0174	glutamine synthetase
CDG60_RS17850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDG60_RS17860	COG0733	neurotransmitter:sodium symporter activity
CDG60_RS17865	COG3738	Protein conserved in bacteria
CDG60_RS17870	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_RS17880	COG2814	Major facilitator Superfamily
CDG60_RS17920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG60_RS17930	COG0657	acetylesterase activity
CDG60_RS17955	COG0484	heat shock protein binding
CDG60_RS17985	COG2951	lytic endotransglycosylase activity
CDG60_RS17990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDG60_RS18005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG60_RS18020	COG2388	GCN5-related N-acetyl-transferase
CDG60_RS18025	COG2388	GCN5-related N-acetyl-transferase
CDG60_RS18035	COG0861	Integral membrane protein TerC family
CDG60_RS18050	COG0754	glutathionylspermidine amidase activity
CDG60_RS18065	COG0402	S-adenosylhomocysteine deaminase activity
CDG60_RS18080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG60_RS18085	COG3111	PFAM Bacterial OB fold (BOF) protein
CDG60_RS18095	COG0706	membrane insertase activity
CDG60_RS18100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDG60_RS18105	COG0594	ribonuclease P activity