locus-tag class description FPL17_RS00035 ENOG4107YZX Universal stress protein FPL17_RS00060 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FPL17_RS00065 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FPL17_RS00080 ENOG4105HBR Rna-binding protein FPL17_RS00090 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FPL17_RS00095 ENOG4105EEI dihydropteroate synthase FPL17_RS00105 ENOG4105CP2 von willebrand factor, type a FPL17_RS00120 ENOG4107U2T alpha beta FPL17_RS00135 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FPL17_RS00140 ENOG4105DIJ Phosphoethanolamine transferase FPL17_RS00145 ENOG4105BZS acriflavin resistance protein FPL17_RS00150 ENOG4105CJW magnesium transporter FPL17_RS00160 ENOG4105D0M Protease HtpX homolog FPL17_RS00165 ENOG4105E4C Lytic transglycosylase catalytic FPL17_RS00180 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) FPL17_RS00185 ENOG4108RRZ Transcription elongation factor GreB FPL17_RS00195 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) FPL17_RS00245 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FPL17_RS00250 ENOG4105C4R Atp-dependent dna helicase FPL17_RS00275 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FPL17_RS00315 ENOG4105CKI cobalamin synthesis protein FPL17_RS00320 ENOG4108VWS Yaeq family FPL17_RS00335 ENOG4107BJW polysaccharide deacetylase FPL17_RS00340 ENOG4105CND Glycosyl transferase, family 2 FPL17_RS00380 ENOG410830R acetyltransferase FPL17_RS00390 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FPL17_RS00395 ENOG4105E98 transcriptional regulator DeoR family FPL17_RS00400 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FPL17_RS00410 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) FPL17_RS00415 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FPL17_RS00435 ENOG41080IJ Diacylglycerol kinase FPL17_RS00445 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FPL17_RS00455 ENOG4105E6M Sulphatase-modifying factor protein FPL17_RS00460 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FPL17_RS00475 ENOG4105D05 Receptor FPL17_RS00490 ENOG4108V9Q carbonic anhydrase FPL17_RS00500 ENOG4108UJV acyl-CoA thioesterase i FPL17_RS00505 ENOG4108I0Y (ABC) transporter FPL17_RS00510 ENOG4105CV6 ABC transporter, permease FPL17_RS00515 ENOG4107ZXI Rhomboid family FPL17_RS00530 ENOG4105EA8 2-Nitropropane dioxygenase FPL17_RS00555 ENOG4107R8N Glycosyl transferase, family 2 FPL17_RS00570 ENOG4105CVP deoxyribo-dipyrimidine photolyase FPL17_RS00575 ENOG4108YZY peptidylprolyl cis-trans isomerase FPL17_RS00580 ENOG4105CEP NADH dehydrogenase FPL17_RS00585 ENOG4105DZ1 carboxypeptidase FPL17_RS00595 ENOG4105VT2 5-hydroxyisourate hydrolase FPL17_RS00615 ENOG4105E9K Isocitrate dehydrogenase FPL17_RS00625 ENOG4108R99 pseudouridine synthase FPL17_RS00650 ENOG4105JAB phenazine biosynthesis protein, phzf family FPL17_RS00670 ENOG4105I7R Adenylate cyclase FPL17_RS00680 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FPL17_RS00695 ENOG4105D3G Pseudouridine synthase FPL17_RS00700 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FPL17_RS00705 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction FPL17_RS00715 ENOG4105EJ2 Transcriptional regulator FPL17_RS00735 ENOG4105MKU Transcriptional regulator FPL17_RS00745 ENOG4105GAV receptor FPL17_RS00750 ENOG4105GAV receptor FPL17_RS00760 ENOG4108JPW Aminotransferase FPL17_RS00765 ENOG4105DY8 decarboxylase FPL17_RS00775 ENOG4105C26 Dehydrogenase FPL17_RS00780 ENOG4105F7P transcriptional regulator AsnC family FPL17_RS00785 ENOG4107RA9 decarboxylase FPL17_RS00790 ENOG4105C85 amino acid FPL17_RS00805 ENOG4105CVA phosphate FPL17_RS00810 ENOG4105C8U phosphate abc transporter FPL17_RS00820 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FPL17_RS00825 ENOG4105ERU peptidase FPL17_RS00850 ENOG4106H78 methyltransferase FPL17_RS00855 ENOG4105CJN penicillin-binding protein FPL17_RS00880 ENOG4105CSM endonuclease III FPL17_RS00885 ENOG4108R3D Electron transport complex FPL17_RS00890 ENOG4105D82 Glutamate dehydrogenase FPL17_RS00900 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FPL17_RS00915 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FPL17_RS00935 ENOG4108821 RND type efflux pump FPL17_RS00965 ENOG4107RAQ aminopeptidase FPL17_RS00970 ENOG4105D0A hydroxylase FPL17_RS00975 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FPL17_RS00995 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FPL17_RS01010 ENOG4105W4M Transport-associated protein FPL17_RS01035 ENOG4108JDX DNA polymerase iii, epsilon subunit FPL17_RS01040 ENOG4105E9H Lytic Murein transglycosylase FPL17_RS01045 ENOG4105E43 Extracellular solute-binding protein, family 5 FPL17_RS01050 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FPL17_RS01055 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FPL17_RS01060 ENOG4108JQ5 ABC transporter FPL17_RS01080 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) FPL17_RS01105 ENOG4105NX3 Membrane FPL17_RS01125 ENOG4105EUJ GTP cyclohydrolase i FPL17_RS01160 ENOG4108ETY sodium dicarboxylate symporter FPL17_RS01165 ENOG4105DDQ anthranilate synthase FPL17_RS01170 ENOG4105C5F glutamine synthetase FPL17_RS01180 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) FPL17_RS01245 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FPL17_RS01255 ENOG4105DTR rard protein FPL17_RS01295 ENOG4107QS8 (LipO)protein FPL17_RS01300 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FPL17_RS01305 ENOG4105C5Q Transcriptional regulator FPL17_RS01315 ENOG4107QZF nitrite reductase NADPH large subunit FPL17_RS01320 ENOG4105VCQ rubredoxin FPL17_RS01330 ENOG4105CRK lysyL-tRNA synthetase FPL17_RS01340 ENOG4108MRJ FPL17_RS01345 ENOG4105C11 sulfate adenylyltransferase), subunit 2 FPL17_RS01350 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FPL17_RS01370 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FPL17_RS01375 ENOG4105C37 (CBS) domain FPL17_RS01385 ENOG4107RET Isocitrate lyase FPL17_RS01390 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FPL17_RS01395 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FPL17_RS01400 ENOG4107QNR UPF0135 protein FPL17_RS01405 ENOG4105C0H protease FPL17_RS01435 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FPL17_RS01440 ENOG4105CE9 30S ribosomal protein S2 FPL17_RS01475 ENOG4105C2X Arabinose 5-phosphate isomerase FPL17_RS01480 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase FPL17_RS01490 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FPL17_RS01495 ENOG4108IUZ ABC transporter FPL17_RS01500 ENOG4105DFG type I secretion outer membrane protein FPL17_RS01505 ENOG4108JJA ABC, transporter FPL17_RS01530 ENOG4108VQJ O-methyltransferase FPL17_RS01540 ENOG4108Z4U Ferredoxin FPL17_RS01550 ENOG4105EE5 Membrane protein terC FPL17_RS01560 ENOG4108WAV Transcriptional regulator FPL17_RS01565 ENOG4105C5A transporter FPL17_RS01585 ENOG4108JIK carboxylase FPL17_RS01595 ENOG4105X58 receptor FPL17_RS01610 ENOG4105CR8 Transcriptional regulator FPL17_RS01620 ENOG4105F04 LysR family Transcriptional regulator FPL17_RS01640 ENOG4105KT5 UmuD protein FPL17_RS01650 ENOG4105CF7 AraC family transcriptional regulator FPL17_RS01655 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS01660 ENOG4105CF7 AraC family transcriptional regulator FPL17_RS01665 ENOG4105ENX hydrolase FPL17_RS01670 ENOG4105ENX hydrolase FPL17_RS01675 ENOG4105EMU Dehydrogenase FPL17_RS01685 ENOG4105HEI LysR family (Transcriptional regulator FPL17_RS01715 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FPL17_RS01720 ENOG4105ERG peptidase m48, ste24p FPL17_RS01735 ENOG4105KTH gatB Yqey FPL17_RS01740 ENOG4105VCC 30S ribosomal protein S21 FPL17_RS01760 ENOG4108UZ3 Transporter FPL17_RS01795 ENOG4105D9P serine threonine protein kinase FPL17_RS01830 ENOG4105F04 LysR family Transcriptional regulator FPL17_RS01840 ENOG4105C85 amino acid FPL17_RS01845 ENOG4105CS6 Rhs element vgr protein FPL17_RS01870 ENOG4107QTF adenylosuccinate lyase FPL17_RS01915 ENOG4108Z0R Transferase FPL17_RS01920 ENOG4105DZ1 carboxypeptidase FPL17_RS01945 ENOG4108K5P (LipO)protein FPL17_RS01950 ENOG4105EJC lysr family transcriptional regulator FPL17_RS01955 ENOG4105DAN ATP-dependent protease FPL17_RS01970 ENOG4105DHU Bile acid FPL17_RS01990 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FPL17_RS01995 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FPL17_RS02000 ENOG4105D22 carbon starvation protein FPL17_RS02005 ENOG4105VCD cytoplasmic protein FPL17_RS02010 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FPL17_RS02020 ENOG4105F8C transglutaminase domain-containing protein FPL17_RS02030 ENOG4105HEI LysR family (Transcriptional regulator FPL17_RS02040 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS02060 ENOG4105C2I pirin domain protein FPL17_RS02075 ENOG4105EGI Transcriptional regulator FPL17_RS02080 ENOG4108Q5Y Membrane FPL17_RS02085 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS02125 ENOG4105CYM Glutathione S-transferase FPL17_RS02130 ENOG4105CMU LysR family (Transcriptional regulator FPL17_RS02135 ENOG4105VAW lrga family FPL17_RS02140 ENOG41067MG lrgb family FPL17_RS02150 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FPL17_RS02155 ENOG4105C85 amino acid FPL17_RS02220 ENOG4108VAU general secretion pathway protein G FPL17_RS02235 ENOG4107QHF type ii secretion system protein e FPL17_RS02260 ENOG4105E4G Type IV pilus FPL17_RS02290 ENOG4105EAD ABC transporter FPL17_RS02295 ENOG4108HW4 amino acid AbC transporter FPL17_RS02305 ENOG4107RP9 extracellular solute-binding protein, family 3 FPL17_RS02310 ENOG4105CT1 (ABC) transporter FPL17_RS02325 ENOG4107YPT transcriptional regulator FPL17_RS02330 ENOG4105EQ0 Major Facilitator superfamily FPL17_RS02350 ENOG4105EU0 Major facilitator Superfamily FPL17_RS02355 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) FPL17_RS02360 ENOG4105T0Z Conserved Protein FPL17_RS02370 ENOG4105CR8 Transcriptional regulator FPL17_RS02385 ENOG4105E39 Enoyl-CoA hydratase FPL17_RS02390 ENOG4107QX3 carboxylase FPL17_RS02395 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS02400 ENOG4105R8C Transcriptional regulator FPL17_RS02405 ENOG4105CEY Amp-dependent synthetase and ligase FPL17_RS02425 ENOG4105D2S major facilitator superfamily FPL17_RS02430 ENOG4105EVZ LysR family transcriptional regulator FPL17_RS02435 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FPL17_RS02440 ENOG4105C26 Dehydrogenase FPL17_RS02450 ENOG4107AQZ Membrane FPL17_RS02465 ENOG4108JPW Aminotransferase FPL17_RS02470 ENOG4105C26 Dehydrogenase FPL17_RS02490 ENOG4105PDP Short chain dehydrogenase FPL17_RS02495 ENOG41069M3 Transcriptional regulator FPL17_RS02525 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase FPL17_RS02530 ENOG4105DJB Major Facilitator Superfamily FPL17_RS02545 ENOG4105CHR reductase FPL17_RS02560 ENOG4105C7K acetolactate synthase FPL17_RS02575 ENOG4105F95 Monooxygenase FPL17_RS02585 ENOG4105CPT Alpha beta hydrolase FPL17_RS02590 ENOG4105EMY transcriptional regulator FPL17_RS02600 ENOG4107Y2X deaminase FPL17_RS02605 ENOG4105DJ2 Major Facilitator Superfamily FPL17_RS02610 ENOG4105CS6 Rhs element vgr protein FPL17_RS02635 ENOG4105EJC lysr family transcriptional regulator FPL17_RS02640 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FPL17_RS02645 ENOG4105C94 Transporter FPL17_RS02655 ENOG4105DVW rieske (2Fe-2S) FPL17_RS02660 ENOG4105C26 Dehydrogenase FPL17_RS02665 ENOG4105E3J oxidoreductase FPL17_RS02670 ENOG4105CEB Aspartate aminotransferase FPL17_RS02680 ENOG4107HP6 Transcriptional regulator FPL17_RS02685 ENOG4107QP7 CoA-transferase subunit A FPL17_RS02690 ENOG4107QNJ CoA-transferase subunit B FPL17_RS02695 ENOG4105CHU acetyl-coa acetyltransferase FPL17_RS02700 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase FPL17_RS02705 ENOG4105F2Z 3-oxoadipate enol-lactonase FPL17_RS02710 ENOG4105D2S major facilitator superfamily FPL17_RS02715 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FPL17_RS02720 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta FPL17_RS02725 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha FPL17_RS02730 ENOG4105FF2 Type I DHQase FPL17_RS02735 ENOG4106JPM 3-dehydroshikimate dehydratase FPL17_RS02740 ENOG4105TW1 Carbohydrate-selective porin OprB FPL17_RS02745 ENOG4105DZG Dehydrogenase FPL17_RS02755 ENOG4105VT2 5-hydroxyisourate hydrolase FPL17_RS02760 ENOG4105C2W permease FPL17_RS02770 ENOG41061H0 Monooxygenase FPL17_RS02775 ENOG41073TP transcriptional regulator FPL17_RS02795 ENOG4107Z6I Thiamine biosynthesis protein FPL17_RS02800 ENOG4105D7T ABC transporter FPL17_RS02805 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FPL17_RS02815 ENOG4105NAE bifunctional deaminase-reductase domain protein FPL17_RS02825 ENOG4105SKE transcriptional Regulator LysR family FPL17_RS02835 ENOG4105CZE histidine utilization repressor FPL17_RS02840 ENOG41090B9 response to stress FPL17_RS02855 ENOG4105C85 amino acid FPL17_RS02865 ENOG41088SP formiminoglutamate hydrolase FPL17_RS02870 ENOG4105D82 Glutamate dehydrogenase FPL17_RS02875 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FPL17_RS02885 ENOG4108ZX5 transcriptional regulator FPL17_RS02890 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FPL17_RS02895 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FPL17_RS02900 ENOG4105C4M (Ubiquinol oxidase) subunit I FPL17_RS02910 ENOG4108ZX5 transcriptional regulator FPL17_RS02915 ENOG4108821 RND type efflux pump FPL17_RS02925 ENOG4108821 RND type efflux pump FPL17_RS02935 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FPL17_RS02940 ENOG4105EZR dyp-type peroxidase family protein FPL17_RS02970 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FPL17_RS02975 ENOG4105BZS acriflavin resistance protein FPL17_RS02980 ENOG4105C1P efflux transporter, rnd family, mfp subunit FPL17_RS02985 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FPL17_RS02995 ENOG4105GR3 Histidine kinase FPL17_RS03000 ENOG4105CPU Monooxygenase FPL17_RS03005 ENOG4105CPC Aldo Keto reductase FPL17_RS03025 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FPL17_RS03045 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FPL17_RS03055 ENOG4107SM7 Transcriptional regulator FPL17_RS03060 ENOG4105X1Q TOBE domain protein FPL17_RS03095 ENOG4105F95 Monooxygenase FPL17_RS03100 ENOG4105JQZ Methyltransferase FPL17_RS03105 ENOG4108K0D peptidase, M48 FPL17_RS03110 ENOG4107RYR Transcriptional regulator, Crp Fnr family FPL17_RS03115 ENOG4108UKZ OsmC family FPL17_RS03125 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FPL17_RS03150 ENOG4105CD3 dihydroorotase FPL17_RS03175 ENOG4105CS6 Rhs element vgr protein FPL17_RS03195 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FPL17_RS03205 ENOG4108K3A Glutathione S-transferase FPL17_RS03215 ENOG4108JU3 Alkyl hydroperoxide reductase FPL17_RS03235 ENOG4105EEF Alkane 1-monooxygenase FPL17_RS03245 ENOG4105D3R alkyl hydroperoxide reductase FPL17_RS03250 ENOG4105CQ7 ATP-dependent helicase FPL17_RS03260 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FPL17_RS03265 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) FPL17_RS03285 ENOG4105CVE Lytic murein transglycosylase FPL17_RS03290 ENOG4105CNI cell division protein FtsW FPL17_RS03305 ENOG4105E3A (ABC) transporter FPL17_RS03310 ENOG4105DA5 (ABC) transporter FPL17_RS03355 ENOG4105MRR Transcriptional regulator (By similarity) FPL17_RS03360 ENOG4108HW3 (ABC) transporter FPL17_RS03385 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FPL17_RS03390 ENOG4105CFP Peptidase U32 FPL17_RS03400 ENOG4108Z12 YiaAB two helix domain-containing protein FPL17_RS03410 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FPL17_RS03415 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FPL17_RS03445 ENOG4108MEJ flavin reductase domain protein FPL17_RS03455 ENOG4107IFA Lipase (EC 3.1.1.3) FPL17_RS03465 ENOG4105D06 uba thif-type nad fad binding protein FPL17_RS03475 ENOG4105KRF dihydroneopterin aldolase FPL17_RS03500 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) FPL17_RS03505 ENOG4105CFU surface antigen FPL17_RS03525 ENOG4107QIJ Aconitate hydratase 2 FPL17_RS03530 ENOG4105E6M Sulphatase-modifying factor protein FPL17_RS03545 ENOG4107QPK )-transporter FPL17_RS03550 ENOG4105EYW Ion transport protein FPL17_RS03555 ENOG4105DHS permease protein FPL17_RS03560 ENOG4105CM4 permease protein FPL17_RS03565 ENOG4108IPW abc transporter atp-binding protein FPL17_RS03575 ENOG4108R5S membrane FPL17_RS03580 ENOG4105F27 Major Facilitator FPL17_RS03605 ENOG4108T86 baseplate J family protein FPL17_RS03670 ENOG4105EFV Major head subunit FPL17_RS03690 ENOG4108QUU Morphogenesis Protein FPL17_RS03695 ENOG4105QIB mu-like prophage Flumu protein gp29 FPL17_RS03710 ENOG4105CF2 Mu-like prophage FluMu protein GP28 FPL17_RS03745 ENOG4105M7P phage repressor FPL17_RS03795 ENOG4105K70 DNA-binding protein FPL17_RS03845 ENOG4105WPN DNA integration recombination invertion protein FPL17_RS03850 ENOG4105DZ2 Transcriptional regulator FPL17_RS03870 ENOG4105DP0 ferredoxin-NADP reductase FPL17_RS03875 ENOG4108R96 Methyltransferase, YaeB family FPL17_RS03880 ENOG4107QHF type ii secretion system protein e FPL17_RS03890 ENOG4105XJC Two component transcriptional regulator (Winged helix family FPL17_RS03895 ENOG4105DHQ Histidine kinase FPL17_RS03905 ENOG4105M6F mutator MutT protein FPL17_RS03915 ENOG4105BZ4 penicillin-binding protein FPL17_RS03920 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FPL17_RS03925 ENOG4105VUT cytoplasmic protein FPL17_RS03930 ENOG4105CS6 Rhs element vgr protein FPL17_RS03955 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS03970 ENOG4105CQC Prephenate dehydratase FPL17_RS03975 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FPL17_RS03985 ENOG4105CIN aminoacyl-histidine dipeptidase FPL17_RS03990 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) FPL17_RS04010 ENOG4105E0Y RtcB Protein FPL17_RS04015 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FPL17_RS04020 ENOG4105CYB regulatoR FPL17_RS04065 ENOG4105M08 Membrane FPL17_RS04070 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FPL17_RS04080 ENOG4105VEQ Cold shock protein FPL17_RS04085 ENOG4105C1J atp-dependent rna helicase FPL17_RS04090 ENOG4105D2N Aldolase FPL17_RS04095 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FPL17_RS04100 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FPL17_RS04105 ENOG4105EHM Aminoglycoside phosphotransferase FPL17_RS04110 ENOG4108S0S Nucleotidyl transferase FPL17_RS04120 ENOG4107QJE Chromosome Partitioning Protein FPL17_RS04125 ENOG4105FA0 parb-like partition protein FPL17_RS04140 ENOG4105BZ1 (ABC) transporter FPL17_RS04145 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) FPL17_RS04155 ENOG4107QRG dna polymerase iii FPL17_RS04175 ENOG4105F8V Hydrolase, tatD family FPL17_RS04200 ENOG4108RTD type II secretion system protein K FPL17_RS04220 ENOG4108Z6B deaminase FPL17_RS04235 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FPL17_RS04240 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) FPL17_RS04270 ENOG4105DWU Membrane FPL17_RS04275 ENOG4108IG5 Transcriptional regulator FPL17_RS04280 ENOG4105C2C drug resistance transporter, Bcr CflA FPL17_RS04285 ENOG4107RN6 Monooxygenase FPL17_RS04295 ENOG4105D6Z AFG1 family ATPase FPL17_RS04335 ENOG4105CWM branched-chain amino acid transport system II carrier protein FPL17_RS04340 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FPL17_RS04345 ENOG4105CC0 LysR family Transcriptional regulator FPL17_RS04350 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FPL17_RS04360 ENOG4105M2J Glutaredoxin FPL17_RS04365 ENOG4105C8Y Acetylornithine aminotransferase FPL17_RS04370 ENOG41080XP Cbs domain FPL17_RS04395 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FPL17_RS04445 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FPL17_RS04450 ENOG4105C4M (Ubiquinol oxidase) subunit I FPL17_RS04485 ENOG4105HDD phospholipase FPL17_RS04495 ENOG4105CZN Potassium uptake protein FPL17_RS04510 ENOG4105C7B Threonine dehydratase FPL17_RS04545 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FPL17_RS04550 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FPL17_RS04560 ENOG4105C5H ABC transporter FPL17_RS04565 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FPL17_RS04570 ENOG4108MXF Alpha Beta Hydrolase FPL17_RS04580 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS04615 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FPL17_RS04620 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FPL17_RS04660 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) FPL17_RS04675 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FPL17_RS04695 ENOG4107RZC phospholipase d FPL17_RS04710 ENOG4105F4R Transcriptional regulator mode FPL17_RS04725 ENOG4105DRR Transcriptional regulator, GntR family FPL17_RS04735 ENOG4105CF7 AraC family transcriptional regulator FPL17_RS04750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FPL17_RS04755 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FPL17_RS04805 ENOG4108IPJ Membrane FPL17_RS04810 ENOG41080UQ Transcriptional regulator FPL17_RS04815 ENOG4105DDY UPF0142 protein ycaO FPL17_RS04825 ENOG4108ZIT Ferredoxin, 2FE-2S FPL17_RS04845 ENOG4107RN6 Monooxygenase FPL17_RS04855 ENOG4108UAJ Transcriptional regulator FPL17_RS04870 ENOG4105GR3 Histidine kinase FPL17_RS04875 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FPL17_RS04890 ENOG4105E18 UPF0276 protein FPL17_RS04900 ENOG4108WQI RNA Polymerase FPL17_RS04925 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FPL17_RS04935 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) FPL17_RS04940 ENOG4105DHQ Histidine kinase FPL17_RS04945 ENOG4105ETX regulatoR FPL17_RS04975 ENOG4105EG6 Saccharopine dehydrogenase FPL17_RS04990 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS05005 ENOG4107SWG transcriptional regulator MERR family FPL17_RS05015 ENOG4107U5X Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FPL17_RS05025 ENOG4108SF5 RNA Polymerase FPL17_RS05035 ENOG4107ENK receptor FPL17_RS05045 ENOG4108R0G Tetratricopeptide repeat protein FPL17_RS05055 ENOG4108YNN Heme oxygenase FPL17_RS05075 ENOG4108SC4 )-transporter FPL17_RS05085 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FPL17_RS05090 ENOG4105C4M (Ubiquinol oxidase) subunit I FPL17_RS05100 ENOG4105D1S lipid A biosynthesis FPL17_RS05115 ENOG4108KB2 LysR family Transcriptional regulator FPL17_RS05120 ENOG4105CHR reductase FPL17_RS05135 ENOG4105CPN adenine deaminase FPL17_RS05190 ENOG4108IND Tetr family transcriptional regulator FPL17_RS05210 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FPL17_RS05215 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) FPL17_RS05230 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase FPL17_RS05250 ENOG4108K70 Transcriptional regulator FPL17_RS05280 ENOG4105EBR Carboxylesterase FPL17_RS05290 ENOG4105DJ2 Major Facilitator Superfamily FPL17_RS05310 ENOG4105ETT transcriptional Regulator, LysR family FPL17_RS05315 ENOG4105CHR reductase FPL17_RS05355 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FPL17_RS05375 ENOG4105IKQ hydratase FPL17_RS05380 ENOG4105DIV Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity) FPL17_RS05405 ENOG4105VYA Uncharacterized conserved protein (DUF2132) FPL17_RS05410 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase FPL17_RS05415 ENOG4105E8V Alpha Beta Hydrolase Fold protein FPL17_RS05420 ENOG41077RS Phosphatase FPL17_RS05435 ENOG4108HPI phosphatidate Cytidylyltransferase FPL17_RS05440 ENOG4108UQN AraC family transcriptional regulator FPL17_RS05445 ENOG4108UZX fmn reductase FPL17_RS05460 ENOG4108YNN Heme oxygenase FPL17_RS05470 ENOG4108SF5 RNA Polymerase FPL17_RS05480 ENOG4105HSS phospholipase C FPL17_RS05490 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria FPL17_RS05500 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FPL17_RS05505 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FPL17_RS05530 ENOG4105DMQ Methyltransferase FPL17_RS05540 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FPL17_RS05550 ENOG4105C28 cystathionine FPL17_RS05600 ENOG4105KPY Small multidrug resistance protein FPL17_RS05610 ENOG4105KUS lysozyme FPL17_RS05620 ENOG4105K59 histidine triad (HIT) protein FPL17_RS05645 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FPL17_RS05675 ENOG4107TSN permease FPL17_RS05680 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FPL17_RS05700 ENOG4105D05 Receptor FPL17_RS05730 ENOG4108YZT Adenosylcobinamide kinase FPL17_RS05740 ENOG4107VXZ Hydrolase FPL17_RS05745 ENOG4105D2S major facilitator superfamily FPL17_RS05775 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FPL17_RS05785 ENOG4105DJU Siderophore biosynthesis protein FPL17_RS05790 ENOG4105DUU IucA IucC family protein FPL17_RS05810 ENOG4108Z66 YbaK ebsC protein FPL17_RS05825 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase FPL17_RS05830 ENOG4107HP6 Transcriptional regulator FPL17_RS05835 ENOG4105C26 Dehydrogenase FPL17_RS05855 ENOG4105CUB amino acid FPL17_RS05870 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FPL17_RS05875 ENOG4105DZS Phenylacetate-CoA ligase FPL17_RS05880 ENOG4105CHU acetyl-coa acetyltransferase FPL17_RS05885 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FPL17_RS05890 ENOG4108UKI Enoyl-CoA hydratase FPL17_RS05895 ENOG4105E39 Enoyl-CoA hydratase FPL17_RS05905 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FPL17_RS05910 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FPL17_RS05915 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FPL17_RS05920 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FPL17_RS05925 ENOG4105DXM phenylacetic acid degradation protein FPL17_RS05935 ENOG4105DNH Major Facilitator FPL17_RS05945 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS05950 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS05955 ENOG4105DC8 reductase FPL17_RS05960 ENOG4105EEF Alkane 1-monooxygenase FPL17_RS05965 ENOG4105E7U AraC family transcriptional regulator FPL17_RS05970 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FPL17_RS05980 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FPL17_RS05990 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FPL17_RS06005 ENOG4105KNE Phosphatidate cytidylyltransferase FPL17_RS06010 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FPL17_RS06020 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FPL17_RS06030 ENOG4105CUX Signal transduction histidine kinase FPL17_RS06035 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FPL17_RS06055 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FPL17_RS06085 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) FPL17_RS06105 ENOG4105T38 integral membrane protein FPL17_RS06110 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FPL17_RS06120 ENOG4105CVM Molybdenum cofactor synthesis domain protein FPL17_RS06125 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FPL17_RS06140 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FPL17_RS06145 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FPL17_RS06185 ENOG4107VMU Membrane FPL17_RS06225 ENOG4105BZC d-serine deaminase FPL17_RS06245 ENOG4105HMI Membrane FPL17_RS06260 ENOG4105F27 Major Facilitator FPL17_RS06270 ENOG4105E2B Taurine dioxygenase FPL17_RS06275 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FPL17_RS06280 ENOG4105EGI Transcriptional regulator FPL17_RS06285 ENOG4105CBP Major Facilitator FPL17_RS06305 ENOG4108IFG nitrite reductase, (NAD(P)H) FPL17_RS06310 ENOG4107QZF nitrite reductase NADPH large subunit FPL17_RS06315 ENOG4107RNU major facilitator superfamily MFS_1 FPL17_RS06335 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FPL17_RS06340 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FPL17_RS06355 ENOG4105D8G Major Facilitator superfamily FPL17_RS06360 ENOG4105C85 amino acid FPL17_RS06370 ENOG4108RXX maleylacetoacetate isomerase FPL17_RS06395 ENOG4105CY2 Citrate transporter FPL17_RS06400 ENOG4105C0A alcohol dehydrogenase FPL17_RS06405 ENOG4105C26 Dehydrogenase FPL17_RS06415 ENOG4105CBC glutamate synthase FPL17_RS06470 ENOG4105VEQ Cold shock protein FPL17_RS06520 ENOG4105C0A alcohol dehydrogenase FPL17_RS06530 ENOG4107QMP dna polymerase iii subunits gamma and tau FPL17_RS06535 ENOG4105EZE Cupin 4 family protein FPL17_RS06555 ENOG41080HT Transcriptional regulator, arsr family FPL17_RS06575 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FPL17_RS06580 ENOG4105CUY Mechanosensitive ion channel FPL17_RS06635 ENOG4105D6U Sodium Glutamate Symporter FPL17_RS06655 ENOG4105BZ1 (ABC) transporter FPL17_RS06660 ENOG4108ZMQ domain protein FPL17_RS06665 ENOG4108ZX5 transcriptional regulator FPL17_RS06680 ENOG4108IJ0 Aspartate ammonia-lyase FPL17_RS06685 ENOG4105CK7 Sodium proline symporter FPL17_RS06690 ENOG4105EW9 transcriptional regulator AsnC family FPL17_RS06695 ENOG4105C26 Dehydrogenase FPL17_RS06705 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) FPL17_RS06730 ENOG41080VW acetyltransferase FPL17_RS06760 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FPL17_RS06765 ENOG4108YYC ycei family FPL17_RS06780 ENOG4105CV1 Transketolase (EC 2.2.1.1) FPL17_RS06805 ENOG4105UCG Domain of unknown function (DUF333) FPL17_RS06810 ENOG4105CJP fad dependent oxidoreductase FPL17_RS06815 ENOG4105VEQ Cold shock protein FPL17_RS06820 ENOG4105VEQ Cold shock protein FPL17_RS06845 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FPL17_RS06850 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FPL17_RS06870 ENOG4105X0I Fimbrial FPL17_RS06885 ENOG4106PIH fimbrial-like protein ydeQ FPL17_RS06940 ENOG4107T8P acyl-Coa dehydrogenase FPL17_RS06955 ENOG4105D01 (LipO)protein FPL17_RS06960 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FPL17_RS06965 ENOG4108UMI ABC transporter, permease FPL17_RS06970 ENOG4105C3G gtp-binding protein FPL17_RS06985 ENOG4105IJJ transcriptional regulator, crp fnr family FPL17_RS07030 ENOG4105J0Q Transcriptional regulator FPL17_RS07055 ENOG4108V06 Glutathione peroxidase FPL17_RS07065 ENOG4105CHM Aminotransferase FPL17_RS07075 ENOG4105C0B DNA polymerase III (alpha subunit) FPL17_RS07100 ENOG4108JU3 Alkyl hydroperoxide reductase FPL17_RS07120 ENOG4108821 RND type efflux pump FPL17_RS07150 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FPL17_RS07185 ENOG41069NU Nitroreductase FPL17_RS07210 ENOG4108UHJ MAF-like protein FPL17_RS07245 ENOG4105CHR reductase FPL17_RS07250 ENOG4105CHU acetyl-coa acetyltransferase FPL17_RS07265 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) FPL17_RS07270 ENOG4105K4T epimerase FPL17_RS07275 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) FPL17_RS07300 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FPL17_RS07305 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FPL17_RS07310 ENOG4105VEJ Heat shock protein FPL17_RS07320 ENOG4105Y3E Modulates RecA activity (By similarity) FPL17_RS07335 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FPL17_RS07340 ENOG4105K70 DNA-binding protein FPL17_RS07355 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family FPL17_RS07365 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FPL17_RS07370 ENOG4108Z4V iron-sulfur cluster assembly FPL17_RS07385 ENOG4108ZIT Ferredoxin, 2FE-2S FPL17_RS07395 ENOG4108Z40 Transcriptional regulator FPL17_RS07400 ENOG4105F8J Adenylate Guanylate cyclase FPL17_RS07410 ENOG4108JA2 transcriptioN-repair coupling factor FPL17_RS07425 ENOG4105DUM transcriptional regulator, lysR family FPL17_RS07430 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FPL17_RS07435 ENOG4108NIW Leucine export protein LeuE FPL17_RS07440 ENOG4105DKK Benzoate FPL17_RS07445 ENOG4105CKD glutathione-regulated potassium-efflux system protein FPL17_RS07460 ENOG4105VK3 rdd domain containing protein FPL17_RS07470 ENOG4105CD8 aminopeptidase N FPL17_RS07500 ENOG4105F4I Transcriptional regulator FPL17_RS07510 ENOG4107QUV Domain protein FPL17_RS07530 ENOG4105CUB amino acid FPL17_RS07535 ENOG4105CPD ethanolamine ammonia-lyase FPL17_RS07545 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FPL17_RS07550 ENOG4105CX6 glutaminyL-tRNA synthetase FPL17_RS07560 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) FPL17_RS07565 ENOG4108RCM Nitroreductase FPL17_RS07570 ENOG4105DYS nad(p)h dehydrogenase (quinone) FPL17_RS07580 ENOG4108TZV Membrane FPL17_RS07595 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FPL17_RS07600 ENOG4105K8N protein family UPF0079, ATPase FPL17_RS07620 ENOG4105I08 Pseudouridine synthase FPL17_RS07630 ENOG4105DEN Luciferase family FPL17_RS07635 ENOG4105BZU Histidine kinase FPL17_RS07655 ENOG4105E2S oxidase) subunit II FPL17_RS07660 ENOG4105BZ9 Cytochrome C oxidase, subunit I FPL17_RS07665 ENOG4105CCU oxidase (Subunit III) FPL17_RS07670 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FPL17_RS07705 ENOG4105CDU Replicative dna helicase FPL17_RS07710 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FPL17_RS07750 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FPL17_RS07770 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FPL17_RS07780 ENOG4105CFH Aspartokinase FPL17_RS07790 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FPL17_RS07800 ENOG4105CPW cytochrome b561 FPL17_RS07805 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FPL17_RS07810 ENOG4105C7N Xanthine uracil vitamin C permease FPL17_RS07820 ENOG4105E0K tonB-dependent siderophore receptor FPL17_RS07835 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FPL17_RS07845 ENOG4105CJ2 (LipO)protein FPL17_RS07895 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FPL17_RS07900 ENOG4105DC1 bifunctional purine biosynthesis protein purh FPL17_RS07905 ENOG4105C12 Phosphoribosylglycinamide synthetase FPL17_RS07915 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FPL17_RS07920 ENOG4108UMI ABC transporter, permease FPL17_RS07935 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FPL17_RS07945 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) FPL17_RS07950 ENOG4105SYT Methylenetetrahydrofolate reductase FPL17_RS07955 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FPL17_RS07960 ENOG4105BZU Histidine kinase FPL17_RS07965 ENOG4105C6K Malic enzyme FPL17_RS07990 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase FPL17_RS07995 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FPL17_RS08000 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) FPL17_RS08010 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FPL17_RS08015 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FPL17_RS08025 ENOG4105C3F Signal peptidase i FPL17_RS08030 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FPL17_RS08050 ENOG4105C0H protease FPL17_RS08055 ENOG4108IYU L-aspartate oxidase FPL17_RS08065 ENOG4105HHA aminodeoxychorismate lyase FPL17_RS08070 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FPL17_RS08075 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FPL17_RS08085 ENOG4108I5D sulfate abc transporter FPL17_RS08095 ENOG4108IJ6 ABC transporter FPL17_RS08100 ENOG4107R11 Transcriptional regulator FPL17_RS08115 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FPL17_RS08120 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FPL17_RS08135 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FPL17_RS08155 ENOG4108UKI Enoyl-CoA hydratase FPL17_RS08160 ENOG4105BZW Glycerate kinase FPL17_RS08165 ENOG4105EGD dinuclear metal center protein, YbgI family FPL17_RS08175 ENOG4105C2C drug resistance transporter, Bcr CflA FPL17_RS08180 ENOG4108ETH Formylglycinamide ribotide synthetase FPL17_RS08205 ENOG4107YD3 Thioesterase FPL17_RS08210 ENOG4105E02 MotA TolQ exbB proton channel FPL17_RS08215 ENOG4105M8F Biopolymer transport protein exbD tolR FPL17_RS08225 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) FPL17_RS08230 ENOG4105KCK Peptidoglycan-associated lipoprotein FPL17_RS08280 ENOG4105C02 permease FPL17_RS08290 ENOG4108V3E phosphoribosylglycinamide formyltransferase FPL17_RS08300 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FPL17_RS08310 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FPL17_RS08315 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FPL17_RS08320 ENOG4105D60 lipoprotein releasing system transmembrane protein FPL17_RS08330 ENOG4108Q5Y Membrane FPL17_RS08335 ENOG4108UPT UPF0178 protein FPL17_RS08385 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) FPL17_RS08390 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FPL17_RS08400 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FPL17_RS08410 ENOG4105C10 Electron transfer flavoprotein FPL17_RS08415 ENOG4105BZJ Electron transfer flavoprotein FPL17_RS08420 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FPL17_RS08425 ENOG4108NIW Leucine export protein LeuE FPL17_RS08430 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) FPL17_RS08435 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FPL17_RS08445 ENOG4105C85 amino acid FPL17_RS08450 ENOG4105BZG amino acid carrier protein FPL17_RS08455 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FPL17_RS08465 ENOG4105CJ3 phosphate transporter FPL17_RS08470 ENOG4105C3R Methionine synthase FPL17_RS08480 ENOG4105WDY DNA (cytosine-5-)-methyltransferase FPL17_RS08485 ENOG4105CSV Glutaminase FPL17_RS08490 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FPL17_RS08535 ENOG4107R72 Ceramidase FPL17_RS08545 ENOG4105E2B Taurine dioxygenase FPL17_RS08550 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FPL17_RS08555 ENOG4108IY8 ABC, transporter FPL17_RS08560 ENOG4106FTQ Taurine ABC transporter, periplasmic FPL17_RS08570 ENOG4105D7W serine acetyltransferase FPL17_RS08575 ENOG4105ESN nucleotide-binding protein FPL17_RS08580 ENOG4105C9B Cysteine desulfurase FPL17_RS08585 ENOG4108NIW Leucine export protein LeuE FPL17_RS08590 ENOG4105EXG Transcriptional regulator FPL17_RS08595 ENOG4105FDP GntR family transcriptional regulator FPL17_RS08615 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FPL17_RS08640 ENOG4105PGM cation diffusion facilitator family transporter FPL17_RS08655 ENOG4105E0C molybdate abc transporter FPL17_RS08660 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FPL17_RS08680 ENOG4108ZG0 Ompa motb domain protein FPL17_RS08735 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FPL17_RS08765 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FPL17_RS08775 ENOG4105CEY Amp-dependent synthetase and ligase FPL17_RS08785 ENOG4105DY2 Paraquat-inducible protein b FPL17_RS08790 ENOG4105F1S paraquat-inducible protein a FPL17_RS08800 ENOG4108IQI permease FPL17_RS08810 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) FPL17_RS08815 ENOG4105C26 Dehydrogenase FPL17_RS08820 ENOG4105F4X arginine FPL17_RS08825 ENOG4105C8Y Acetylornithine aminotransferase FPL17_RS08830 ENOG4105D82 Glutamate dehydrogenase FPL17_RS08840 ENOG4107R1I NAD-dependent malic enzyme FPL17_RS08875 ENOG4107QPN acyl-Coa dehydrogenase FPL17_RS08880 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FPL17_RS08930 ENOG4105D05 Receptor FPL17_RS08935 ENOG4105EPF Outer membrane porin FPL17_RS08940 ENOG4108KB2 LysR family Transcriptional regulator FPL17_RS08945 ENOG4105DTQ mandelate racemase muconate lactonizing FPL17_RS08950 ENOG4105NN7 muconolactone delta-isomerase FPL17_RS08960 ENOG4107QP7 CoA-transferase subunit A FPL17_RS08965 ENOG4107QNJ CoA-transferase subunit B FPL17_RS08970 ENOG4105CHU acetyl-coa acetyltransferase FPL17_RS08975 ENOG4105F2Z 3-oxoadipate enol-lactonase FPL17_RS08990 ENOG4105C26 Dehydrogenase FPL17_RS09005 ENOG4105F11 amine oxidase FPL17_RS09025 ENOG4105CHR reductase FPL17_RS09035 ENOG4105FUY alpha subunit FPL17_RS09050 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FPL17_RS09060 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FPL17_RS09075 ENOG4105JHE Major Facilitator Superfamily FPL17_RS09115 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FPL17_RS09140 ENOG4105CS6 Rhs element vgr protein FPL17_RS09145 ENOG4105CNM Receptor FPL17_RS09150 ENOG4108Z4X TRANSCRIPTIONal FPL17_RS09160 ENOG410624X efflux transporter, rnd family, mfp subunit FPL17_RS09165 ENOG4105BZS acriflavin resistance protein FPL17_RS09180 ENOG4105F95 Monooxygenase FPL17_RS09200 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS09205 ENOG4107GD3 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity) FPL17_RS09210 ENOG4105EMU Dehydrogenase FPL17_RS09215 ENOG4108ZX5 transcriptional regulator FPL17_RS09220 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FPL17_RS09225 ENOG4105FB2 class II Aldolase FPL17_RS09230 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FPL17_RS09260 ENOG4105C84 Histidine ammonia-lyase FPL17_RS09265 ENOG4105C94 Transporter FPL17_RS09295 ENOG4105EMU Dehydrogenase FPL17_RS09305 ENOG4106P55 Transcriptional regulator FPL17_RS09320 ENOG4106P55 Transcriptional regulator FPL17_RS09325 ENOG4107EFR Flavocytochrome c FPL17_RS09340 ENOG4105F95 Monooxygenase FPL17_RS09350 ENOG41062JF Transcriptional regulator FPL17_RS09360 ENOG4108UU4 oxidoreductase (Short chain dehydrogenase reductase family) FPL17_RS09375 ENOG4105MXB limonene-12-epoxide hydrolase FPL17_RS09450 ENOG4108JJB ABC transporter FPL17_RS09515 ENOG4105DFP Integrase FPL17_RS09525 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FPL17_RS09530 ENOG4105C0R drug resistance transporter emrb qaca subfamily FPL17_RS09535 ENOG4105CW7 secretion protein, HlyD family FPL17_RS09545 ENOG4105D2S major facilitator superfamily FPL17_RS09550 ENOG4105F57 Anthranilate dioxygenase reductase FPL17_RS09555 ENOG4108YS2 small subunit FPL17_RS09560 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit FPL17_RS09565 ENOG4108I0C methyltransferase FPL17_RS09570 ENOG4108VUY thioesterase Superfamily protein FPL17_RS09575 ENOG4105D52 delta-aminolevulinic acid dehydratase FPL17_RS09580 ENOG4105MWK D-amino acid dehydrogenase, small subunit FPL17_RS09585 ENOG4105ECP epimerase FPL17_RS09605 ENOG4105E9F Enoyl-CoA hydratase FPL17_RS09610 ENOG4107RH8 nuclease SbcCD subunit D FPL17_RS09615 ENOG4105EYH Exonuclease FPL17_RS09630 ENOG4105DFA alanine racemase domain protein FPL17_RS09635 ENOG4105CZX twitching motility protein FPL17_RS09640 ENOG4105CZX twitching motility protein FPL17_RS09645 ENOG41090R7 Ferric uptake FPL17_RS09670 ENOG4105E7A Glutamine amidotransferase FPL17_RS09690 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FPL17_RS09695 ENOG4105C4R Atp-dependent dna helicase FPL17_RS09700 ENOG4108ZG0 Ompa motb domain protein FPL17_RS09705 ENOG4106HNH Acyl-transferase FPL17_RS09715 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) FPL17_RS09720 ENOG4107QMS site-determining protein FPL17_RS09740 ENOG4105CNU cell division protein FtsK FPL17_RS09745 ENOG4105C3M thioredoxin reductase FPL17_RS09755 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) FPL17_RS09765 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FPL17_RS09785 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FPL17_RS09795 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FPL17_RS09810 ENOG4108YXA Membrane FPL17_RS09820 ENOG4105C4K Nad synthetase FPL17_RS09845 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FPL17_RS09865 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FPL17_RS09870 ENOG4105C34 Pseudouridine synthase FPL17_RS09875 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FPL17_RS09880 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FPL17_RS09900 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) FPL17_RS09930 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FPL17_RS09965 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FPL17_RS09970 ENOG4107XGZ Hydrolase FPL17_RS09975 ENOG4105DWF phosphomethylpyrimidine kinase FPL17_RS09980 ENOG4109066 lysm domain bon superfamily protein FPL17_RS09990 ENOG4105CHR reductase FPL17_RS09995 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FPL17_RS10000 ENOG4105VGS 50s ribosomal protein l32 FPL17_RS10005 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FPL17_RS10010 ENOG4108BPE -transporting atpase FPL17_RS10015 ENOG4107RTD sua5 ycio yrdc ywlc family protein FPL17_RS10035 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FPL17_RS10040 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FPL17_RS10045 ENOG4105FE9 pseudouridine synthase FPL17_RS10065 ENOG4105DGW oligopeptidase A FPL17_RS10075 ENOG4105DIB Oligopeptide-binding protein FPL17_RS10100 ENOG4105SG9 biopolymer transport protein, ExbD FPL17_RS10115 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FPL17_RS10120 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FPL17_RS10130 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FPL17_RS10140 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FPL17_RS10145 ENOG4108KB2 LysR family Transcriptional regulator FPL17_RS10150 ENOG4105FUY alpha subunit FPL17_RS10155 ENOG4108UKV benzoate 1,2-dioxygenase FPL17_RS10160 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein FPL17_RS10165 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase FPL17_RS10170 ENOG4105DKK Benzoate FPL17_RS10175 ENOG4105D2S major facilitator superfamily FPL17_RS10195 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FPL17_RS10205 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FPL17_RS10225 ENOG4105HF0 Membrane FPL17_RS10230 ENOG4108EKN Biotin protein ligase C terminal domain FPL17_RS10245 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FPL17_RS10255 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FPL17_RS10315 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FPL17_RS10320 ENOG4105D1F ATP-binding protein FPL17_RS10335 ENOG4108YYQ gCN5-related N-acetyltransferase FPL17_RS10350 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FPL17_RS10360 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FPL17_RS10370 ENOG4105F2W methyltransferase FPL17_RS10395 ENOG4105K6H D-cysteine desulfhydrase FPL17_RS10400 ENOG4105CBX hi0933 family FPL17_RS10425 ENOG4105DP0 ferredoxin-NADP reductase FPL17_RS10430 ENOG4105DUM transcriptional regulator, lysR family FPL17_RS10455 ENOG4105C8S subunit m FPL17_RS10460 ENOG4105D65 subunit l FPL17_RS10465 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FPL17_RS10470 ENOG4107UFS subunit j FPL17_RS10475 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FPL17_RS10485 ENOG4108IEH NADH dehydrogenase subunit g FPL17_RS10490 ENOG4107QIZ NADH dehydrogenase FPL17_RS10495 ENOG4105GKE subunit e FPL17_RS10500 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FPL17_RS10510 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FPL17_RS10515 ENOG4105BZU Histidine kinase FPL17_RS10535 ENOG4105JJR Histidine kinase FPL17_RS10540 ENOG4107EXC regulatoR FPL17_RS10545 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FPL17_RS10555 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FPL17_RS10560 ENOG4107QTH restriction modification system DNA specificity domain FPL17_RS10570 ENOG4108F3G Type I restriction-modification system, R subunit FPL17_RS10575 ENOG4105R8C Transcriptional regulator FPL17_RS10580 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) FPL17_RS10585 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FPL17_RS10605 ENOG4107SFI Major Facilitator superfamily FPL17_RS10615 ENOG4105C94 Transporter FPL17_RS10620 ENOG4105C94 Transporter FPL17_RS10625 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FPL17_RS10680 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FPL17_RS10685 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FPL17_RS10690 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FPL17_RS10715 ENOG4105E3B Multicopper oxidase FPL17_RS10725 ENOG4105DJV ribulose-phosphate 3-epimerase FPL17_RS10750 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FPL17_RS10755 ENOG41072GX Peptidase M22 Glycoprotease FPL17_RS10765 ENOG4105P8F nudix hydrolase FPL17_RS10815 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FPL17_RS10825 ENOG4108KPJ rna polymerase sigma factor FPL17_RS10830 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FPL17_RS10835 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FPL17_RS10905 ENOG4108ZHJ Organic hydroperoxide resistance protein FPL17_RS10910 ENOG4107QHF type ii secretion system protein e FPL17_RS10930 ENOG4105C2M dna polymerase I FPL17_RS10935 ENOG4105EXC Acyl-transferase FPL17_RS10940 ENOG4108VIA integral membrane protein FPL17_RS10945 ENOG4105II7 pyrroline-5-carboxylate reductase FPL17_RS10950 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FPL17_RS10960 ENOG4105C9X ppx gppa phosphatase FPL17_RS10970 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FPL17_RS10985 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FPL17_RS11015 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FPL17_RS11030 ENOG4105W39 Membrane FPL17_RS11045 ENOG4105CYM Glutathione S-transferase FPL17_RS11065 ENOG4105CEY Amp-dependent synthetase and ligase FPL17_RS11070 ENOG4105N42 UPF0307 protein FPL17_RS11095 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FPL17_RS11100 ENOG4105DJ0 Poly(A) Polymerase FPL17_RS11105 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FPL17_RS11110 ENOG4105DXN mazG family FPL17_RS11125 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FPL17_RS11140 ENOG4105C6T cysteine synthase FPL17_RS11145 ENOG4105BZU Histidine kinase FPL17_RS11155 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FPL17_RS11160 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FPL17_RS11180 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FPL17_RS11185 ENOG4105W8H transhydrogenase (subunit alpha FPL17_RS11190 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FPL17_RS11210 ENOG4105BZU Histidine kinase FPL17_RS11215 ENOG4108WQH regulatoR FPL17_RS11220 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FPL17_RS11235 ENOG4105CUZ uba thif-type nad fad binding protein FPL17_RS11245 ENOG4107QM5 aconitate hydratase FPL17_RS11250 ENOG4105F8V Hydrolase, tatD family FPL17_RS11255 ENOG4108ZJ4 polysaccharide deacetylase FPL17_RS11265 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FPL17_RS11275 ENOG4105F04 LysR family Transcriptional regulator FPL17_RS11310 ENOG4105D6J arsenicaL-resistance protein FPL17_RS11315 ENOG4105KBH arsR family transcriptional regulator FPL17_RS11340 ENOG4105VZ8 Transcriptional regulator FPL17_RS11355 ENOG4105BZU Histidine kinase FPL17_RS11365 ENOG4108ZP8 Acetolactate synthase small subunit FPL17_RS11370 ENOG4105C7K acetolactate synthase FPL17_RS11390 ENOG4105JF9 DNA polymerase III, delta FPL17_RS11395 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FPL17_RS11400 ENOG4105DJY efflux transporter, rnd family, mfp subunit FPL17_RS11405 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FPL17_RS11410 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FPL17_RS11425 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FPL17_RS11435 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FPL17_RS11440 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FPL17_RS11450 ENOG4105VW4 glutaredoxin 3 FPL17_RS11475 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FPL17_RS11485 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FPL17_RS11495 ENOG4105FFC UPF0187 protein FPL17_RS11500 ENOG4105CPC Aldo Keto reductase FPL17_RS11505 ENOG4105EJC lysr family transcriptional regulator FPL17_RS11510 ENOG4105DB7 PHP domain protein FPL17_RS11540 ENOG4108VPT UPF0234 protein FPL17_RS11555 ENOG4108ZGC gaf domain protein FPL17_RS11560 ENOG4105NAU thioesterase Superfamily protein FPL17_RS11570 ENOG4107U2T alpha beta FPL17_RS11575 ENOG4107QPB Beta-lactamase domain protein FPL17_RS11615 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FPL17_RS11620 ENOG4105D6S protein involved in catabolism of external DNA FPL17_RS11640 ENOG4105D9Z Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FPL17_RS11650 ENOG4105E4C Lytic transglycosylase catalytic FPL17_RS11660 ENOG4105C9A Phoh family FPL17_RS11675 ENOG4105CNM Receptor FPL17_RS11700 ENOG4108XI2 Domain of unknown function (DUF1963) FPL17_RS11705 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) FPL17_RS11745 ENOG4105CIY formyltetrahydrofolate deformylase FPL17_RS11750 ENOG41062JF Transcriptional regulator FPL17_RS11755 ENOG4107RGH Aldehyde dehydrogenase FPL17_RS11760 ENOG4105KDC 50s ribosomal protein l28 FPL17_RS11765 ENOG4105W0E 50S ribosomal protein L33 FPL17_RS11770 ENOG4105CKD glutathione-regulated potassium-efflux system protein FPL17_RS11800 ENOG4105C4R Atp-dependent dna helicase FPL17_RS11815 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FPL17_RS11825 ENOG4105KVH Transcriptional regulator FPL17_RS11835 ENOG41069P5 Protein slyX homolog FPL17_RS11840 ENOG4105C5H ABC transporter FPL17_RS11845 ENOG4108UVJ appr-1-p processing domain protein FPL17_RS11850 ENOG4105D1S lipid A biosynthesis FPL17_RS11930 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FPL17_RS11945 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FPL17_RS11980 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FPL17_RS11985 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FPL17_RS11995 ENOG4105CH6 catalase FPL17_RS12000 ENOG4105KIR Thiol-disulfide oxidoreductase dcc FPL17_RS12015 ENOG4108W5M transcriptional regulator FPL17_RS12030 ENOG4107XGZ Hydrolase FPL17_RS12035 ENOG4105EI2 Pseudouridine synthase FPL17_RS12045 ENOG4105C03 ribonuclease FPL17_RS12050 ENOG4105J5T Amp-dependent synthetase and ligase FPL17_RS12065 ENOG4105CSA Coproporphyrinogen iii oxidase FPL17_RS12075 ENOG4107QI1 Mate efflux family protein FPL17_RS12115 ENOG4105EW6 flavin reductase domain protein, FMN-binding FPL17_RS12130 ENOG4105BZ8 glutamate synthase FPL17_RS12140 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) FPL17_RS12150 ENOG4105C5X domain protein FPL17_RS12165 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FPL17_RS12175 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FPL17_RS12180 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) FPL17_RS12185 ENOG4108JU5 Magnesium and cobalt efflux protein FPL17_RS12190 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FPL17_RS12195 ENOG4108Z7R Chaperone CsaA FPL17_RS12210 ENOG4108VAU general secretion pathway protein G FPL17_RS12215 ENOG4105D7Q type ii secretion system FPL17_RS12220 ENOG4105C25 Primosomal protein n' FPL17_RS12225 ENOG4105CKD glutathione-regulated potassium-efflux system protein FPL17_RS12230 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FPL17_RS12250 ENOG4107QUT magnesium and cobalt transport protein CorA FPL17_RS12255 ENOG4105CK2 sodium dicarboxylate symporter FPL17_RS12260 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FPL17_RS12265 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FPL17_RS12275 ENOG4107QYX exodeoxyribonuclease v alpha FPL17_RS12280 ENOG4107QKA exodeoxyribonuclease V beta FPL17_RS12285 ENOG4105DSY exodeoxyribonuclease V, gamma FPL17_RS12300 ENOG4105CSR polyphosphate kinase 2 FPL17_RS12310 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FPL17_RS12320 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) FPL17_RS12325 ENOG4105CPW cytochrome b561 FPL17_RS12330 ENOG41061H0 Monooxygenase FPL17_RS12335 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase FPL17_RS12345 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FPL17_RS12360 ENOG4105D65 subunit l FPL17_RS12365 ENOG4108ZE9 Monovalent cation H antiporter subunit C FPL17_RS12370 ENOG4107R4Z monovalent cation h antiporter subunit d FPL17_RS12375 ENOG4105SC1 monovalent cation H antiporter subunit E FPL17_RS12380 ENOG4105W4C monovalent cation H antiporter subunit F FPL17_RS12385 ENOG4105KJM monovalent cation h antiporter subunit g FPL17_RS12390 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FPL17_RS12400 ENOG4105CHV Transcription elongation factor NusA FPL17_RS12435 ENOG4107QHF type ii secretion system protein e FPL17_RS12450 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FPL17_RS12460 ENOG4105C2N RNA methyltransferase TrmH family group 3 FPL17_RS12465 ENOG4105NBK UPF0345 protein FPL17_RS12470 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FPL17_RS12480 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FPL17_RS12495 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) FPL17_RS12505 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FPL17_RS12550 ENOG4105MJ9 esterase FPL17_RS12565 ENOG4105BZ1 (ABC) transporter FPL17_RS12575 ENOG4107ZXU DSBA oxidoreductase FPL17_RS12595 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FPL17_RS12610 ENOG4105D3Y Na H antiporter FPL17_RS12645 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FPL17_RS12650 ENOG4108VZM 50s ribosomal protein L10 FPL17_RS12655 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) FPL17_RS12660 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FPL17_RS12665 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FPL17_RS12670 ENOG4105PM1 preprotein translocase subunit SecE FPL17_RS12710 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FPL17_RS12715 ENOG4105TV9 FHA Domain-Containing protein FPL17_RS12720 ENOG4105GVR general secretion pathway protein D FPL17_RS12735 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS FPL17_RS12760 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FPL17_RS12765 ENOG4108NEV two component transcriptional regulator, LytTR family FPL17_RS12770 ENOG4108HRK Histidine kinase FPL17_RS12785 ENOG4108UTW Plays a role in the regulation of phosphate uptake FPL17_RS12800 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FPL17_RS12805 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FPL17_RS12810 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FPL17_RS12815 ENOG4105CNI cell division protein FtsW FPL17_RS12835 ENOG4105CE1 Ferrous iron transport protein b FPL17_RS12845 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FPL17_RS12850 ENOG4105T95 Thiol disulfide interChange protein FPL17_RS12855 ENOG4105D6E homoserine dehydrogenase FPL17_RS12875 ENOG41061WM D-Alanyl-D-Alanine FPL17_RS12885 ENOG4107TUY Histidine kinase FPL17_RS12890 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FPL17_RS12895 ENOG4105CN1 protease FPL17_RS12900 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FPL17_RS12905 ENOG4108K5H permease YjgP YjgQ family protein FPL17_RS12910 ENOG4108M8S permease YjgP YjgQ family protein FPL17_RS12935 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FPL17_RS12945 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FPL17_RS12955 ENOG4105BZU Histidine kinase FPL17_RS12970 ENOG4105C0P Mg chelatase subunit ChlI FPL17_RS12995 ENOG4105F0N pyrophosphate phospho-hydrolase FPL17_RS13010 ENOG4105CEY Amp-dependent synthetase and ligase FPL17_RS13015 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FPL17_RS13020 ENOG4105EN6 Membrane FPL17_RS13025 ENOG4105K5B UPF0225 protein FPL17_RS13030 ENOG4105EE5 Membrane protein terC FPL17_RS13035 ENOG4108URH decarboxylase FPL17_RS13045 ENOG4105C0R drug resistance transporter emrb qaca subfamily FPL17_RS13060 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FPL17_RS13065 ENOG4105E3W Two component transcriptional regulator (Winged helix family FPL17_RS13070 ENOG4105EB3 Histidine kinase FPL17_RS13075 ENOG4105CT7 inner membrane cred family protein FPL17_RS13095 ENOG4105CCT upf0313 protein FPL17_RS13105 ENOG4105D94 Major Facilitator Superfamily FPL17_RS13115 ENOG4105W1Y Transcriptional regulator FPL17_RS13125 ENOG4105CS1 NAD(P)H quinone oxidoreductase FPL17_RS13145 ENOG4105C6T cysteine synthase FPL17_RS13180 ENOG4105C94 Transporter FPL17_RS13190 ENOG4107RGD Major Facilitator superfamily FPL17_RS13195 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS13200 ENOG4105ETT transcriptional Regulator, LysR family FPL17_RS13220 ENOG4107QN1 sodium solute FPL17_RS13225 ENOG41062QD Membrane FPL17_RS13230 ENOG4105BZU Histidine kinase FPL17_RS13255 ENOG4108WZM domain protein FPL17_RS13260 ENOG4105C79 DNA protecting protein DprA FPL17_RS13275 ENOG4108IND Tetr family transcriptional regulator FPL17_RS13280 ENOG4105F27 Major Facilitator FPL17_RS13285 ENOG4107RTG Major Facilitator superfamily FPL17_RS13295 ENOG4108V06 Glutathione peroxidase FPL17_RS13305 ENOG41090VV Protein of unknown function (DUF2846) FPL17_RS13310 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FPL17_RS13315 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FPL17_RS13325 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) FPL17_RS13340 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FPL17_RS13365 ENOG4105FDK ABC transporter FPL17_RS13370 ENOG4105FAV ABC, transporter FPL17_RS13375 ENOG410829K Lysine exporter protein (Lyse ygga) FPL17_RS13380 ENOG4105EZR dyp-type peroxidase family protein FPL17_RS13405 ENOG4105EUB pirin domain protein FPL17_RS13420 ENOG41090R7 Ferric uptake FPL17_RS13445 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FPL17_RS13455 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FPL17_RS13460 ENOG4106MP8 UPF0754 membrane protein FPL17_RS13465 ENOG4105H4F exported protein FPL17_RS13470 ENOG4108VBZ doxx family FPL17_RS13475 ENOG4105DQR SNARE associated Golgi FPL17_RS13490 ENOG4107QJE Chromosome Partitioning Protein FPL17_RS13500 ENOG4107PSF BolA-like protein FPL17_RS13520 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FPL17_RS13530 ENOG4105H3G oxidoreductase FPL17_RS13535 ENOG4105KME endoribonuclease L-psp FPL17_RS13555 ENOG4105C26 Dehydrogenase FPL17_RS13560 ENOG4105CSH Transporter FPL17_RS13570 ENOG4105E39 Enoyl-CoA hydratase FPL17_RS13575 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS13585 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FPL17_RS13590 ENOG4105C26 Dehydrogenase FPL17_RS13600 ENOG4105C85 amino acid FPL17_RS13615 ENOG4105EW9 transcriptional regulator AsnC family FPL17_RS13625 ENOG4108W0I acetyltransferase FPL17_RS13630 ENOG4105D3G Pseudouridine synthase FPL17_RS13665 ENOG4108I0Z Aconitate hydratase FPL17_RS13670 ENOG4105BZN citrate synthase FPL17_RS13675 ENOG4105CR4 methylisocitrate lyase FPL17_RS13680 ENOG4105DRR Transcriptional regulator, GntR family FPL17_RS13685 ENOG4105CGF Aromatic amino acid aminotransferase FPL17_RS13690 ENOG4105CXG d-lactate dehydrogenase FPL17_RS13700 ENOG41073TP transcriptional regulator FPL17_RS13705 ENOG4105DAA L-lactate FPL17_RS13710 ENOG4107QKV phosphomannomutase FPL17_RS13715 ENOG4105CMR udp-glucose 4-epimerase FPL17_RS13725 ENOG4105C6Y Udp-glucose 6-dehydrogenase FPL17_RS13730 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FPL17_RS13745 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FPL17_RS13750 ENOG4107WZ3 Transferase FPL17_RS13755 ENOG4105D3Q Sugar transferase FPL17_RS13765 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FPL17_RS13790 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FPL17_RS13795 ENOG4105J5G Transferase hexapeptide repeat containing protein FPL17_RS13800 ENOG4107R5Z Oxidoreductase domain protein FPL17_RS13805 ENOG4107QQG Dehydrogenase FPL17_RS13810 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FPL17_RS13815 ENOG4105DAY polysaccharide export protein FPL17_RS13825 ENOG4105D75 Capsular exopolysaccharide family FPL17_RS13830 ENOG4108V1T peptidylprolyl cis-trans isomerase FPL17_RS13835 ENOG4108V1T peptidylprolyl cis-trans isomerase FPL17_RS13840 ENOG4105CJR Integral membrane protein (MviN FPL17_RS13845 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FPL17_RS13850 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FPL17_RS13860 ENOG4105HSS phospholipase C FPL17_RS13885 ENOG41062JF Transcriptional regulator FPL17_RS13900 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FPL17_RS13905 ENOG4105UBK short-chain dehydrogenase reductase FPL17_RS13915 ENOG4107QZM n-acetylglutamate synthase FPL17_RS13920 ENOG4105GVF (ABC) transporter FPL17_RS13925 ENOG4105GVF (ABC) transporter FPL17_RS13930 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FPL17_RS13935 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FPL17_RS13940 ENOG4108VM9 ABC, transporter FPL17_RS13945 ENOG4108W9H Tetr family transcriptional regulator FPL17_RS13955 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FPL17_RS13965 ENOG4105DTN riboflavin biosynthesis protein ribF FPL17_RS13970 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FPL17_RS13980 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FPL17_RS13990 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FPL17_RS14025 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FPL17_RS14055 ENOG4105CFG Acts as a chaperone (By similarity) FPL17_RS14060 ENOG4107T8T UPF0173 metal-dependent hydrolase FPL17_RS14090 ENOG4105CVE Lytic murein transglycosylase FPL17_RS14095 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FPL17_RS14100 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FPL17_RS14110 ENOG4105DFU Cell wall formation (By similarity) FPL17_RS14135 ENOG4105DQS Transcriptional regulator FPL17_RS14145 ENOG4105DU1 integral membrane protein, terc FPL17_RS14160 ENOG4106032 Glutathionylspermidine synthase FPL17_RS14170 ENOG4107QUY Guanine deaminase FPL17_RS14175 ENOG4108UGV hypoxanthine phosphoribosyltransferase FPL17_RS14185 ENOG4105T95 Thiol disulfide interChange protein FPL17_RS14190 ENOG4105CZX twitching motility protein FPL17_RS14200 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FPL17_RS14215 ENOG4105VG0 50S ribosomal protein l34 FPL17_RS14225 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FPL17_RS14235 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FPL17_RS14245 ENOG4105DQR SNARE associated Golgi FPL17_RS14250 ENOG4105C5H ABC transporter FPL17_RS14255 ENOG4108821 RND type efflux pump FPL17_RS14260 ENOG4108821 RND type efflux pump FPL17_RS14265 ENOG4108821 RND type efflux pump FPL17_RS14270 ENOG4108821 RND type efflux pump FPL17_RS14280 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) FPL17_RS14285 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FPL17_RS14345 ENOG4105C8J )-transporter FPL17_RS14355 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FPL17_RS14385 ENOG4105C2W permease FPL17_RS14395 ENOG4105J7D transcriptional regulator FPL17_RS14400 ENOG4105DJY efflux transporter, rnd family, mfp subunit FPL17_RS14430 ENOG4105F27 Major Facilitator FPL17_RS14435 ENOG4105CV8 reductase FPL17_RS14440 ENOG4105HEI LysR family (Transcriptional regulator FPL17_RS14450 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FPL17_RS14455 ENOG4105DQ4 alcohol dehydrogenase FPL17_RS14460 ENOG4108R3E Dna-3-methyladenine glycosylase i FPL17_RS14475 ENOG4105CEN a g-specific adenine glycosylase FPL17_RS14495 ENOG4105D8V Glucose sorbosone dehydrogenase FPL17_RS14505 ENOG4105D1H recombination factor protein RarA FPL17_RS14525 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FPL17_RS14530 ENOG4105C8V SAICAR synthetase FPL17_RS14540 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FPL17_RS14545 ENOG4108RWI nicotinamidase FPL17_RS14560 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FPL17_RS14570 ENOG4108ZAI phosphatidylglycerophosphatase a FPL17_RS14575 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FPL17_RS14580 ENOG4107YIM Involved in the transcription termination process (By similarity) FPL17_RS14590 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FPL17_RS14600 ENOG4105EAC phosphoserine phosphatase FPL17_RS14635 ENOG4105KHC sulfurtransferase FPL17_RS14645 ENOG4105CR8 Transcriptional regulator FPL17_RS14655 ENOG4105JAB phenazine biosynthesis protein, phzf family FPL17_RS14660 ENOG4108KB2 LysR family Transcriptional regulator FPL17_RS14665 ENOG4105EJC lysr family transcriptional regulator FPL17_RS14680 ENOG4105BZU Histidine kinase FPL17_RS14685 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FPL17_RS14700 ENOG4107QJQ Mate efflux family protein FPL17_RS14705 ENOG4105CHM Aminotransferase FPL17_RS14710 ENOG4106BRA Membrane FPL17_RS14725 ENOG4105D9M gamma-glutamylcysteine synthetase FPL17_RS14740 ENOG4105K4H Nlp p60 protein FPL17_RS14760 ENOG4105IPS esterase FPL17_RS14765 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FPL17_RS14770 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein FPL17_RS14775 ENOG4105C32 Amino acid ABC transporter (Permease) FPL17_RS14785 ENOG4105C0Z ABC transporter FPL17_RS14790 ENOG4108IV0 ABC, transporter FPL17_RS14825 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FPL17_RS14850 ENOG4105KUZ arsenate reductase FPL17_RS14855 ENOG4105CGK Exodeoxyribonuclease III FPL17_RS14865 ENOG4105CPF Cell wall formation (By similarity) FPL17_RS14905 ENOG4108RG3 short-chain dehydrogenase reductase FPL17_RS14915 ENOG4105K56 Transcriptional regulator FPL17_RS14920 ENOG4108V06 Glutathione peroxidase FPL17_RS14925 ENOG4105D7Z glutathione synthase FPL17_RS14945 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FPL17_RS14950 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FPL17_RS14955 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FPL17_RS14975 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FPL17_RS14980 ENOG4107QSN dihydrolipoamide acetyltransferase FPL17_RS15005 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FPL17_RS15020 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FPL17_RS15040 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FPL17_RS15045 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FPL17_RS15055 ENOG4105D64 Mechanosensitive ion channel FPL17_RS15065 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FPL17_RS15070 ENOG4108W2Y isochorismatase FPL17_RS15080 ENOG4105FBW Monooxygenase FPL17_RS15085 ENOG4108UZX fmn reductase FPL17_RS15100 ENOG4108HWY Beta-lactamase FPL17_RS15105 ENOG4105BZU Histidine kinase FPL17_RS15110 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FPL17_RS15115 ENOG4108WUH Transcriptional regulator, TetR family FPL17_RS15135 ENOG4105DWF phosphomethylpyrimidine kinase FPL17_RS15145 ENOG4107RDB Major Facilitator FPL17_RS15150 ENOG4108UUM single-stranded DNA-binding protein FPL17_RS15175 ENOG4105CHJ isochorismatase hydrolase FPL17_RS15180 ENOG4105EUB pirin domain protein FPL17_RS15210 ENOG4105CHR reductase FPL17_RS15330 ENOG4105DFH Transport of potassium into the cell (By similarity) FPL17_RS15345 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FPL17_RS15360 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) FPL17_RS15385 ENOG4107T8P acyl-Coa dehydrogenase FPL17_RS15405 ENOG4105CHH sulfate transporter FPL17_RS15430 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FPL17_RS15460 ENOG4105CYC Transferase FPL17_RS15465 ENOG4105E0F Histidine kinase FPL17_RS15470 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FPL17_RS15505 ENOG4105CBN LysR family transcriptional regulator FPL17_RS15510 ENOG4105D4T Citrate transporter FPL17_RS15520 ENOG4105CSH Transporter FPL17_RS15525 ENOG4105W1Y Transcriptional regulator FPL17_RS15530 ENOG4107P5I polyketide synthase FPL17_RS15535 ENOG4105PDP Short chain dehydrogenase FPL17_RS15545 ENOG4105C5H ABC transporter FPL17_RS15605 ENOG4108IQI permease FPL17_RS15630 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FPL17_RS15640 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FPL17_RS15645 ENOG4105CJN penicillin-binding protein FPL17_RS15650 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FPL17_RS15655 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FPL17_RS15665 ENOG4105DHI Methyltransferase FPL17_RS15670 ENOG4108JQC penicillin-binding protein 1A FPL17_RS15695 ENOG4105E4G Type IV pilus FPL17_RS15715 ENOG4105CBC glutamate synthase FPL17_RS15720 ENOG4105BZ8 glutamate synthase FPL17_RS15725 ENOG4105C57 major facilitator superfamily FPL17_RS15735 ENOG4108V0P LemA family FPL17_RS15740 ENOG4105HA9 of methanol dehydrogenase type FPL17_RS15770 ENOG4108YSG O-Antigen polymerase FPL17_RS15775 ENOG4108UQY Iron-storage protein FPL17_RS15780 ENOG4105W53 bacterioferritin-associated ferredoxin FPL17_RS15785 ENOG4105KME endoribonuclease L-psp FPL17_RS15790 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FPL17_RS15800 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FPL17_RS15805 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FPL17_RS15875 ENOG4105K5M 30s ribosomal protein S16 FPL17_RS15880 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FPL17_RS15890 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FPL17_RS15895 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FPL17_RS15915 ENOG4107AQZ Membrane FPL17_RS15920 ENOG4108JQ1 Dehydrogenase FPL17_RS15925 ENOG4105CQB FAD linked oxidase domain protein FPL17_RS15945 ENOG4105VRH Antibiotic biosynthesis monooxygenase FPL17_RS15950 ENOG4105NF4 modulator of drug activity FPL17_RS15965 ENOG4107QF7 multi-drug FPL17_RS15970 ENOG4105EM2 membrane FPL17_RS15975 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FPL17_RS15980 ENOG4105IPI Membrane FPL17_RS15985 ENOG4107SKI cobyrinic Acid a,c-diamide synthase FPL17_RS15995 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FPL17_RS16030 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FPL17_RS16075 ENOG4105W87 Cbs domain FPL17_RS16080 ENOG41067S9 phage shock protein C, PspC FPL17_RS16090 ENOG4105CSU acyl-Coa dehydrogenase FPL17_RS16105 ENOG4108TGR phosphatase FPL17_RS16110 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) FPL17_RS16135 ENOG4105C1J atp-dependent rna helicase FPL17_RS16140 ENOG4105DHJ ABC, transporter FPL17_RS16145 ENOG4105CY3 ABC transporter, permease FPL17_RS16150 ENOG4107PE3 Mammalian cell entry related domain protein FPL17_RS16155 ENOG4105E3I toluene tolerance FPL17_RS16170 ENOG4105D7N magnesium and cobalt transport protein CorA FPL17_RS16175 ENOG4108URH decarboxylase FPL17_RS16185 ENOG4105MJ2 Competence protein FPL17_RS16190 ENOG4105CB5 ATP-dependent DNA helicase recG FPL17_RS16205 ENOG4105E55 glycerol-3-phosphate acyltransferase FPL17_RS16210 ENOG4105C29 acyl-CoA thioesterase FPL17_RS16235 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FPL17_RS16240 ENOG4105D7A ATP-binding protein FPL17_RS16250 ENOG41089BK Glutamine amido-transferase FPL17_RS16260 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FPL17_RS16280 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FPL17_RS16285 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FPL17_RS16345 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FPL17_RS16360 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FPL17_RS16365 ENOG41067V7 50S ribosomal protein L36 FPL17_RS16375 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FPL17_RS16380 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FPL17_RS16390 ENOG4108ZT0 50S ribosomal protein l17 FPL17_RS16410 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS16450 ENOG4105EMK carboxylate amino acid amine transporter FPL17_RS16455 ENOG4108W3Q Transcriptional regulator FPL17_RS16475 ENOG4105DGW oligopeptidase A FPL17_RS16485 ENOG4105VSH 4-oxalocrotonate tautomerase FPL17_RS16490 ENOG4105CHR reductase FPL17_RS16495 ENOG4105HEI LysR family (Transcriptional regulator FPL17_RS16500 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FPL17_RS16550 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FPL17_RS16565 ENOG4107S2Z UPF0761 membrane protein FPL17_RS16570 ENOG4105CS1 NAD(P)H quinone oxidoreductase FPL17_RS16590 ENOG4105G6Z alkaline phosphatase FPL17_RS16645 ENOG4105DWV Homoserine O-trans-acetylase FPL17_RS16655 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FPL17_RS16665 ENOG4108ESX Receptor FPL17_RS16675 ENOG4107E2E PKHD-type hydroxylase FPL17_RS16680 ENOG4108ESX Receptor FPL17_RS16685 ENOG4105D05 Receptor FPL17_RS16695 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FPL17_RS16715 ENOG4107GFK fumarate FPL17_RS16725 ENOG4105DWP Membrane FPL17_RS16735 ENOG4108DNC Involved in acetate metabolism (By similarity) FPL17_RS16740 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FPL17_RS16765 ENOG4105CN1 protease FPL17_RS16795 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FPL17_RS16805 ENOG4107RZC phospholipase d FPL17_RS16815 ENOG4105UYK outer membrane protein a FPL17_RS16820 ENOG4108KHX Diguanylate cyclase FPL17_RS16875 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS16895 ENOG4108RZE Tetr family transcriptional regulator FPL17_RS16915 ENOG4107QX3 carboxylase FPL17_RS16920 ENOG4105C1G acyl-Coa dehydrogenase FPL17_RS16975 ENOG4105KB2 stringent starvation protein b FPL17_RS16980 ENOG4107MKT Stringent starvation protein a FPL17_RS16990 ENOG4108UJD 30S ribosomal protein S9 FPL17_RS16995 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FPL17_RS17005 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FPL17_RS17010 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FPL17_RS17015 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FPL17_RS17030 ENOG4105WVQ Fe-S assembly protein IscX FPL17_RS17070 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FPL17_RS17085 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FPL17_RS17090 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FPL17_RS17095 ENOG4105VIE preprotein translocase, subunit YajC FPL17_RS17210 ENOG41063XI Toxic component of a toxin-antitoxin (TA) module. A FPL17_RS17215 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FPL17_RS17225 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FPL17_RS17365 ENOG4105ED4 portal protein FPL17_RS17375 ENOG41068JE domain protein FPL17_RS17380 ENOG4105BZU Histidine kinase FPL17_RS17385 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) FPL17_RS17390 ENOG4105CM2 brancheD-chain amino acid aminotransferase FPL17_RS17405 ENOG4105C6Y Udp-glucose 6-dehydrogenase FPL17_RS17430 ENOG4107J0A lipopolysaccharide biosynthetic process FPL17_RS17440 ENOG4107J0A lipopolysaccharide biosynthetic process FPL17_RS17465 ENOG4105C9M aspartyl-trna synthetase FPL17_RS17480 ENOG4105KVH Transcriptional regulator FPL17_RS17520 ENOG4105CSU acyl-Coa dehydrogenase FPL17_RS17525 ENOG4105CSU acyl-Coa dehydrogenase FPL17_RS17535 ENOG4105EB3 Histidine kinase FPL17_RS17540 ENOG4105E3W Two component transcriptional regulator (Winged helix family FPL17_RS17550 ENOG4105CNG UPF0061 protein FPL17_RS17570 ENOG4108WBT adenosyltransferase FPL17_RS17585 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FPL17_RS17595 ENOG4107T31 5'-nucleotidase FPL17_RS17635 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FPL17_RS17660 ENOG4105D3R alkyl hydroperoxide reductase FPL17_RS17680 ENOG4105CSH Transporter FPL17_RS17685 ENOG4108UT2 hemolysin iii FPL17_RS17695 ENOG41082BV acetyltransferase FPL17_RS17720 ENOG4105CHU acetyl-coa acetyltransferase FPL17_RS17730 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FPL17_RS17740 ENOG4105I4A GCN5-related N-acetyltransferase FPL17_RS17745 ENOG4108R6W Transcriptional regulator, ARAC family FPL17_RS17750 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FPL17_RS17755 ENOG4105TW1 Carbohydrate-selective porin OprB FPL17_RS17760 ENOG4105DZG Dehydrogenase FPL17_RS17765 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FPL17_RS17775 ENOG410814C multidrug resistance protein FPL17_RS17785 ENOG4105CHU acetyl-coa acetyltransferase FPL17_RS17795 ENOG4108WHA ompa motb domain protein FPL17_RS17800 ENOG4108WHA ompa motb domain protein FPL17_RS17805 ENOG4105E0Y RtcB Protein FPL17_RS17810 ENOG4108IQI permease FPL17_RS17820 ENOG4105C2W permease FPL17_RS17840 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FPL17_RS17850 ENOG4105CHB tonB-dependent Receptor FPL17_RS17860 ENOG4105T95 Thiol disulfide interChange protein FPL17_RS17875 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FPL17_RS17890 ENOG4105K78 MarR family Transcriptional regulator FPL17_RS17895 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FPL17_RS17900 ENOG4105KWI UPF0339 protein FPL17_RS17915 ENOG4108UNF response regulator FPL17_RS17920 ENOG4105M3Z response regulator FPL17_RS17925 ENOG4108ZGA chew protein FPL17_RS17930 ENOG4105C8Q Methyl-accepting chemotaxis FPL17_RS17935 ENOG4105CBS Chea signal transduction histidine kinase FPL17_RS17960 ENOG4105WD1 Membrane FPL17_RS17965 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FPL17_RS18010 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FPL17_RS18025 ENOG4105EM2 membrane FPL17_RS18030 ENOG4105C2C drug resistance transporter, Bcr CflA FPL17_RS18045 ENOG4105D6U Sodium Glutamate Symporter FPL17_RS18050 ENOG4105BZG amino acid carrier protein FPL17_RS18055 ENOG4105D78 K07001 NTE family protein FPL17_RS18065 ENOG4105C9K Endothelin-converting enzyme 1 FPL17_RS18110 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FPL17_RS18120 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FPL17_RS18125 ENOG4105DFF Rod shape-determining protein mreb FPL17_RS18130 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FPL17_RS18140 ENOG4108Z03 MAF-like protein FPL17_RS18145 ENOG4105C03 ribonuclease FPL17_RS18155 ENOG4105D8T Acyltransferase FPL17_RS18165 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein FPL17_RS18180 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FPL17_RS18185 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FPL17_RS18190 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) FPL17_RS18195 ENOG4105C08 Histidine kinase FPL17_RS18200 ENOG4105EEX Two component transcriptional regulator (Winged helix family FPL17_RS18205 ENOG4106B0W Curli production assembly transport component CsgG FPL17_RS18215 ENOG4107Y60 (LipO)protein FPL17_RS18220 ENOG4107RGH Aldehyde dehydrogenase FPL17_RS18225 ENOG4108R6W Transcriptional regulator, ARAC family FPL17_RS18230 ENOG4105D4T Citrate transporter FPL17_RS18240 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FPL17_RS18245 ENOG4105CFQ glutamine synthetase FPL17_RS18265 ENOG4105C85 amino acid FPL17_RS18270 ENOG4105C7F AcnD-accessory protein PrpF FPL17_RS18275 ENOG4105CTB Polyprenyl synthetase FPL17_RS18285 ENOG4105MSB protein, conserved in bacteria FPL17_RS18300 ENOG4105D78 K07001 NTE family protein FPL17_RS18320 ENOG4105DIJ Phosphoethanolamine transferase FPL17_RS18325 ENOG4105XJC Two component transcriptional regulator (Winged helix family FPL17_RS18330 ENOG4105DHQ Histidine kinase FPL17_RS18345 ENOG4105CDA abc transporter atp-binding protein FPL17_RS18350 ENOG4105DRP amino acid AbC transporter FPL17_RS18355 ENOG4105EAD ABC transporter FPL17_RS18360 ENOG4107RP9 extracellular solute-binding protein, family 3 FPL17_RS18385 ENOG4108M0I Transcriptional regulator FPL17_RS18405 ENOG4105WDY DNA (cytosine-5-)-methyltransferase FPL17_RS18410 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FPL17_RS18435 ENOG4105FCD Major Facilitator FPL17_RS18440 ENOG4105K8R UPF0145 protein FPL17_RS18445 ENOG4105K8R UPF0145 protein FPL17_RS18450 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FPL17_RS18455 ENOG4105BZS acriflavin resistance protein FPL17_RS18460 ENOG4105C1P efflux transporter, rnd family, mfp subunit FPL17_RS18465 ENOG410841Q phosphoesterase PA-phosphatase related protein FPL17_RS18490 ENOG4105EUB pirin domain protein FPL17_RS18495 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) FPL17_RS18510 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FPL17_RS18515 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FPL17_RS18525 ENOG4105KVH Transcriptional regulator FPL17_RS18535 ENOG4105CUB amino acid FPL17_RS18540 ENOG4105C0A alcohol dehydrogenase FPL17_RS18550 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FPL17_RS18555 ENOG4108Z43 UPF0250 protein FPL17_RS18560 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FPL17_RS18585 ENOG4107T5V SNARE associated Golgi FPL17_RS18590 ENOG4105C72 UPF0176 protein FPL17_RS18610 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FPL17_RS18615 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FPL17_RS18625 ENOG4105E33 succinate dehydrogenase FPL17_RS18635 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FPL17_RS18640 ENOG4105C7S Dehydrogenase FPL17_RS18645 ENOG4107QN2 dihydrolipoyl dehydrogenase FPL17_RS18655 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FPL17_RS18660 ENOG4107S78 Band 7 protein FPL17_RS18665 ENOG4105PV3 Inner membrane protein yqiJ FPL17_RS18675 ENOG4105CKW Inner membrane protein yedI FPL17_RS18680 ENOG4105CGZ zinc metallopeptidase FPL17_RS18685 ENOG4105EEQ Na H antiporter