locus-tag	class	description
AhaeAN4_RS00010	COG0592	DNA-directed DNA polymerase activity
AhaeAN4_RS00020	COG0187	DNA topoisomerase II activity
AhaeAN4_RS00025	COG0586	Pfam SNARE associated Golgi protein
AhaeAN4_RS00030	COG0488	(ABC) transporter
AhaeAN4_RS00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AhaeAN4_RS00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AhaeAN4_RS00100	COG3273	potassium ion transport
AhaeAN4_RS00100	COG0471	metal ion transport
AhaeAN4_RS00110	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN4_RS00115	COG3738	Protein conserved in bacteria
AhaeAN4_RS00120	COG0733	neurotransmitter:sodium symporter activity
AhaeAN4_RS00160	COG2233	PERMEase
AhaeAN4_RS00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN4_RS00190	COG0484	heat shock protein binding
AhaeAN4_RS00205	COG2814	Major facilitator Superfamily
AhaeAN4_RS00210	COG0656	L-ascorbic acid biosynthetic process
AhaeAN4_RS00215	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS00230	COG1064	alcohol dehydrogenase
AhaeAN4_RS00235	COG2818	Glycosylase
AhaeAN4_RS00250	COG1194	a g-specific adenine glycosylase
AhaeAN4_RS00260	COG5487	UPF0391 membrane protein
AhaeAN4_RS00265	COG2983	Belongs to the UPF0260 family
AhaeAN4_RS00270	COG2133	pyrroloquinoline quinone binding
AhaeAN4_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AhaeAN4_RS00290	COG1228	amidohydrolase
AhaeAN4_RS00295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AhaeAN4_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AhaeAN4_RS00310	COG1335	isochorismatase
AhaeAN4_RS00315	COG1522	sequence-specific DNA binding
AhaeAN4_RS00360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AhaeAN4_RS00370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AhaeAN4_RS00375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AhaeAN4_RS00380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AhaeAN4_RS00400	COG0560	Phosphoserine phosphatase
AhaeAN4_RS00400	COG3830	Belongs to the UPF0237 family
AhaeAN4_RS00445	COG1278	Cold shock
AhaeAN4_RS00495	COG0436	Aminotransferase
AhaeAN4_RS00505	COG2733	membrane
AhaeAN4_RS00520	COG2918	glutathione biosynthetic process
AhaeAN4_RS00535	COG3150	esterase
AhaeAN4_RS00555	COG0559	Belongs to the binding-protein-dependent transport system permease family
AhaeAN4_RS00570	COG0410	ABC transporter
AhaeAN4_RS00580	COG1247	-acetyltransferase
AhaeAN4_RS00610	COG0625	glutathione transferase activity
AhaeAN4_RS00630	COG1393	Belongs to the ArsC family
AhaeAN4_RS00635	COG0708	Exodeoxyribonuclease III
AhaeAN4_RS00675	COG2801	Transposase and inactivated derivatives
AhaeAN4_RS00690	COG0386	Belongs to the glutathione peroxidase family
AhaeAN4_RS00695	COG0189	ligase activity
AhaeAN4_RS00715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AhaeAN4_RS00750	COG0508	dehydrogenase complex catalyzes the overall conversion of
AhaeAN4_RS00760	COG2119	membrane
AhaeAN4_RS00780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN4_RS00780	COG0426	domain, Protein
AhaeAN4_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AhaeAN4_RS00840	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN4_RS00845	COG1519	Transferase
AhaeAN4_RS00855	COG0668	transmembrane transport
AhaeAN4_RS00860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AhaeAN4_RS00890	COG3706	GGDEF domain
AhaeAN4_RS00925	COG0351	phosphomethylpyrimidine kinase
AhaeAN4_RS00925	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN4_RS00925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AhaeAN4_RS00935	COG2814	Major facilitator Superfamily
AhaeAN4_RS00955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN4_RS00960	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN4_RS00970	COG1335	isochorismatase
AhaeAN4_RS00980	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AhaeAN4_RS01040	COG0582	viral genome integration into host DNA
AhaeAN4_RS01050	COG3158	transport of potassium into the cell
AhaeAN4_RS01065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AhaeAN4_RS01085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AhaeAN4_RS01105	COG0659	secondary active sulfate transmembrane transporter activity
AhaeAN4_RS01120	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS01125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AhaeAN4_RS01160	COG0427	acetyl-CoA hydrolase
AhaeAN4_RS01165	COG2205	protein histidine kinase activity
AhaeAN4_RS01170	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN4_RS01200	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS01210	COG0789	Transcriptional regulator
AhaeAN4_RS01215	COG3320	Male sterility
AhaeAN4_RS01215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AhaeAN4_RS01225	COG4221	oxidoreductase activity
AhaeAN4_RS01235	COG0488	(ABC) transporter
AhaeAN4_RS01305	COG0833	amino acid
AhaeAN4_RS01330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AhaeAN4_RS01350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AhaeAN4_RS01355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AhaeAN4_RS01360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AhaeAN4_RS01365	COG2226	methyltransferase
AhaeAN4_RS01415	COG0067	glutamate synthase
AhaeAN4_RS01415	COG0069	glutamate synthase activity
AhaeAN4_RS01415	COG0070	glutamate synthase
AhaeAN4_RS01420	COG0493	'glutamate synthase
AhaeAN4_RS01430	COG1704	LemA family
AhaeAN4_RS01435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AhaeAN4_RS01450	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS01480	COG3307	-O-antigen
AhaeAN4_RS01490	COG2906	2 iron, 2 sulfur cluster binding
AhaeAN4_RS01500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AhaeAN4_RS01510	COG0194	GDP metabolic process
AhaeAN4_RS01515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AhaeAN4_RS01525	COG4969	Belongs to the N-Me-Phe pilin family
AhaeAN4_RS01605	COG0228	four-way junction DNA binding
AhaeAN4_RS01610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AhaeAN4_RS01620	COG0335	large ribosomal subunit rRNA binding
AhaeAN4_RS01630	COG5380	lipid catabolic process
AhaeAN4_RS01635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AhaeAN4_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AhaeAN4_RS01680	COG0277	FAD linked oxidase domain protein
AhaeAN4_RS01685	COG1484	DNA-dependent DNA replication
AhaeAN4_RS01690	COG4584	PFAM Integrase catalytic
AhaeAN4_RS01690	COG2390	Transcriptional regulator
AhaeAN4_RS01735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AhaeAN4_RS01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN4_RS01755	COG1289	transmembrane transporter activity
AhaeAN4_RS01760	COG0628	permease
AhaeAN4_RS01765	COG1192	Involved in chromosome partitioning
AhaeAN4_RS01775	COG2226	methyltransferase
AhaeAN4_RS01810	COG1404	Belongs to the peptidase S8 family
AhaeAN4_RS01820	COG2072	flavoprotein involved in K transport
AhaeAN4_RS01875	COG0471	metal ion transport
AhaeAN4_RS01885	COG4372	Transposase
AhaeAN4_RS01895	COG2963	transposase activity
AhaeAN4_RS01910	COG1983	PspC domain protein
AhaeAN4_RS01920	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS01980	COG1127	ABC transporter
AhaeAN4_RS01985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AhaeAN4_RS01990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AhaeAN4_RS01995	COG2854	intermembrane phospholipid transfer
AhaeAN4_RS02010	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS02020	COG0598	Magnesium transport protein CorA
AhaeAN4_RS02035	COG1040	competence protein
AhaeAN4_RS02040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AhaeAN4_RS02055	COG2937	Belongs to the GPAT DAPAT family
AhaeAN4_RS02060	COG1946	Acyl-CoA thioesterase
AhaeAN4_RS02065	COG1301	dicarboxylic acid transport
AhaeAN4_RS02090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AhaeAN4_RS02090	COG1017	nitric oxide dioxygenase activity
AhaeAN4_RS02095	COG0433	COG0433 Predicted ATPase
AhaeAN4_RS02115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AhaeAN4_RS02135	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AhaeAN4_RS02185	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AhaeAN4_RS02220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AhaeAN4_RS02230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AhaeAN4_RS02245	COG0203	ribosomal protein L17
AhaeAN4_RS02265	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS02270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AhaeAN4_RS02295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AhaeAN4_RS02365	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AhaeAN4_RS02390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN4_RS02415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AhaeAN4_RS02420	COG0534	Mate efflux family protein
AhaeAN4_RS02430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AhaeAN4_RS02450	COG1530	ribonuclease E activity
AhaeAN4_RS02460	COG0564	pseudouridine synthase activity
AhaeAN4_RS02480	COG0625	glutathione transferase activity
AhaeAN4_RS02500	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AhaeAN4_RS02515	COG0494	nUDIX hydrolase
AhaeAN4_RS02550	COG0473	3-isopropylmalate dehydrogenase activity
AhaeAN4_RS02600	COG1560	Kdo2-lipid A biosynthetic process
AhaeAN4_RS02625	COG1733	regulation of RNA biosynthetic process
AhaeAN4_RS02650	COG0210	DNA helicase
AhaeAN4_RS02670	COG4651	solute:proton antiporter activity
AhaeAN4_RS02670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AhaeAN4_RS02675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AhaeAN4_RS02680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AhaeAN4_RS02695	COG0788	formyltetrahydrofolate deformylase activity
AhaeAN4_RS02760	COG4773	Receptor
AhaeAN4_RS02775	COG1702	phosphate starvation-inducible protein PhoH
AhaeAN4_RS02785	COG0741	lytic transglycosylase activity
AhaeAN4_RS02785	COG1196	nuclear chromosome segregation
AhaeAN4_RS02785	COG0739	heme binding
AhaeAN4_RS02815	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AhaeAN4_RS02820	COG1183	phosphatidylcholine synthase activity
AhaeAN4_RS02870	COG3453	Protein conserved in bacteria
AhaeAN4_RS02870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AhaeAN4_RS02885	COG1607	acyl-coa hydrolase
AhaeAN4_RS02890	COG1956	GAF domain-containing protein
AhaeAN4_RS02905	COG1666	GTP binding
AhaeAN4_RS02940	COG3781	membrane
AhaeAN4_RS02950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AhaeAN4_RS02960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AhaeAN4_RS02985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AhaeAN4_RS02995	COG1162	GTPase activity
AhaeAN4_RS03000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AhaeAN4_RS03035	COG1538	Outer membrane efflux protein
AhaeAN4_RS03040	COG1136	(ABC) transporter
AhaeAN4_RS03040	COG0577	efflux transmembrane transporter activity
AhaeAN4_RS03045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN4_RS03050	COG1466	dna polymerase III delta subunit
AhaeAN4_RS03070	COG0028	Belongs to the TPP enzyme family
AhaeAN4_RS03075	COG0440	acetolactate synthase activity
AhaeAN4_RS03080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AhaeAN4_RS03130	COG4372	Transposase
AhaeAN4_RS03140	COG2963	transposase activity
AhaeAN4_RS03180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AhaeAN4_RS03195	COG0084	hydrolase, TatD family'
AhaeAN4_RS03210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AhaeAN4_RS03220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AhaeAN4_RS03265	COG2963	transposase activity
AhaeAN4_RS03275	COG4372	Transposase
AhaeAN4_RS03325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AhaeAN4_RS03335	COG0732	type I restriction modification DNA specificity domain
AhaeAN4_RS03360	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AhaeAN4_RS03390	COG0640	Transcriptional regulator
AhaeAN4_RS03400	COG0798	PFAM Bile acid sodium symporter
AhaeAN4_RS03405	COG0431	NADPH-dependent FMN reductase
AhaeAN4_RS03415	COG0456	acetyltransferase
AhaeAN4_RS03420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN4_RS03430	COG5285	phytanoyl-CoA dioxygenase
AhaeAN4_RS03435	COG2814	Major facilitator Superfamily
AhaeAN4_RS03445	COG0789	Transcriptional regulator
AhaeAN4_RS03450	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AhaeAN4_RS03455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AhaeAN4_RS03460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AhaeAN4_RS03480	COG3622	Belongs to the hyi family
AhaeAN4_RS03485	COG2084	Dehydrogenase
AhaeAN4_RS03490	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS03495	COG5002	protein histidine kinase activity
AhaeAN4_RS03495	COG2205	protein histidine kinase activity
AhaeAN4_RS03495	COG0784	Response regulator, receiver
AhaeAN4_RS03515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AhaeAN4_RS03555	COG3956	TIGRFAM MazG family protein
AhaeAN4_RS03560	COG1555	photosystem II stabilization
AhaeAN4_RS03565	COG0617	tRNA 3'-terminal CCA addition
AhaeAN4_RS03570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AhaeAN4_RS03595	COG3028	Belongs to the UPF0307 family
AhaeAN4_RS03600	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN4_RS03620	COG0625	glutathione transferase activity
AhaeAN4_RS03635	COG1238	metal cluster binding
AhaeAN4_RS03645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AhaeAN4_RS03665	COG0072	phenylalanine-tRNA ligase activity
AhaeAN4_RS03690	COG0248	Ppx GppA phosphatase
AhaeAN4_RS03700	COG0037	tRNA processing
AhaeAN4_RS03715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AhaeAN4_RS03715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AhaeAN4_RS03740	COG1764	response to oxidative stress
AhaeAN4_RS03750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AhaeAN4_RS03815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AhaeAN4_RS03820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AhaeAN4_RS03825	COG1595	DNA-templated transcription, initiation
AhaeAN4_RS03835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AhaeAN4_RS03870	COG0494	nUDIX hydrolase
AhaeAN4_RS03880	COG1214	PFAM Peptidase M22, glycoprotease
AhaeAN4_RS03885	COG1968	undecaprenyl-diphosphatase activity
AhaeAN4_RS03910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AhaeAN4_RS03920	COG2132	Multicopper oxidase
AhaeAN4_RS03940	COG2076	Multidrug Resistance protein
AhaeAN4_RS03945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AhaeAN4_RS03950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AhaeAN4_RS03955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AhaeAN4_RS03995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AhaeAN4_RS04010	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS04015	COG2205	protein histidine kinase activity
AhaeAN4_RS04040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN4_RS04050	COG0649	NAD binding
AhaeAN4_RS04050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN4_RS04060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AhaeAN4_RS04075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN4_RS04085	COG0713	ATP synthesis coupled electron transport
AhaeAN4_RS04090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AhaeAN4_RS04095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN4_RS04130	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS04150	COG0668	transmembrane transport
AhaeAN4_RS04155	COG2081	HI0933 family
AhaeAN4_RS04160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AhaeAN4_RS04190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AhaeAN4_RS04190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AhaeAN4_RS04210	COG0489	protein tyrosine kinase activity
AhaeAN4_RS04280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AhaeAN4_RS04305	COG0730	response to heat
AhaeAN4_RS04315	COG1196	nuclear chromosome segregation
AhaeAN4_RS04325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AhaeAN4_RS04340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AhaeAN4_RS04350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AhaeAN4_RS04350	COG0596	Alpha beta hydrolase
AhaeAN4_RS04350	COG2226	methyltransferase
AhaeAN4_RS04370	COG4106	trans-aconitate 2-methyltransferase activity
AhaeAN4_RS04420	COG0747	negative chemotaxis
AhaeAN4_RS04450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AhaeAN4_RS04455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AhaeAN4_RS04475	COG0009	L-threonylcarbamoyladenylate synthase
AhaeAN4_RS04480	COG3101	peptidyl-lysine hydroxylation
AhaeAN4_RS04485	COG1399	metal-binding, possibly nucleic acid-binding protein
AhaeAN4_RS04490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AhaeAN4_RS04515	COG1652	LysM domain
AhaeAN4_RS04525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AhaeAN4_RS04525	COG0351	phosphomethylpyrimidine kinase
AhaeAN4_RS04525	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN4_RS04535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AhaeAN4_RS04570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AhaeAN4_RS04595	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AhaeAN4_RS04625	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS04640	COG0358	DNA primase activity
AhaeAN4_RS04650	COG0564	pseudouridine synthase activity
AhaeAN4_RS04780	COG2217	Heavy metal translocating P-type atpase
AhaeAN4_RS04785	COG2205	protein histidine kinase activity
AhaeAN4_RS04800	COG2132	Multicopper oxidase
AhaeAN4_RS04865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN4_RS04880	COG0582	viral genome integration into host DNA
AhaeAN4_RS04890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AhaeAN4_RS04915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AhaeAN4_RS04915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AhaeAN4_RS04950	COG0049	tRNA binding
AhaeAN4_RS04960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AhaeAN4_RS04975	COG0456	acetyltransferase
AhaeAN4_RS04985	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AhaeAN4_RS04990	COG0492	ferredoxin-NADP+ reductase activity
AhaeAN4_RS04995	COG1674	ftsk spoiiie
AhaeAN4_RS04995	COG0531	amino acid
AhaeAN4_RS05000	COG1280	lysine exporter protein (LysE YggA)
AhaeAN4_RS05010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AhaeAN4_RS05015	COG2894	cell division
AhaeAN4_RS05020	COG0850	regulation of cytokinetic process
AhaeAN4_RS05030	COG0204	Acyl-transferase
AhaeAN4_RS05035	COG2885	chlorophyll binding
AhaeAN4_RS05040	COG0210	DNA helicase
AhaeAN4_RS05045	COG0756	dUTP diphosphatase activity
AhaeAN4_RS05050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AhaeAN4_RS05065	COG0121	glutamine amidotransferase
AhaeAN4_RS05080	COG2914	Belongs to the UPF0125 (RnfH) family
AhaeAN4_RS05085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AhaeAN4_RS05140	COG0420	3'-5' exonuclease activity
AhaeAN4_RS05160	COG1090	epimerase
AhaeAN4_RS05165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AhaeAN4_RS05175	COG2050	protein possibly involved in aromatic compounds catabolism
AhaeAN4_RS05180	COG1566	PFAM secretion protein HlyD family protein
AhaeAN4_RS05185	COG2814	Major facilitator Superfamily
AhaeAN4_RS05200	COG4221	oxidoreductase activity
AhaeAN4_RS05205	COG4689	acetoacetate decarboxylase
AhaeAN4_RS05215	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN4_RS05215	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN4_RS05245	COG0625	glutathione transferase activity
AhaeAN4_RS05270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AhaeAN4_RS05280	COG1454	alcohol dehydrogenase
AhaeAN4_RS05285	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS05295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN4_RS05300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN4_RS05310	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN4_RS05325	COG0833	amino acid
AhaeAN4_RS05330	COG0281	malic enzyme
AhaeAN4_RS05335	COG1414	Transcriptional regulator
AhaeAN4_RS05340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN4_RS05360	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS05370	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN4_RS05375	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS05410	COG1607	acyl-coa hydrolase
AhaeAN4_RS05420	COG0523	cobalamin synthesis protein
AhaeAN4_RS05425	COG4681	YaeQ
AhaeAN4_RS05470	COG2388	GCN5-related N-acetyl-transferase
AhaeAN4_RS05480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AhaeAN4_RS05525	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AhaeAN4_RS05545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AhaeAN4_RS05580	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AhaeAN4_RS05600	COG4771	TonB-dependent receptor
AhaeAN4_RS05620	COG0456	acetyltransferase
AhaeAN4_RS05630	COG4181	ATPase activity
AhaeAN4_RS05635	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AhaeAN4_RS05645	COG0457	Tetratricopeptide repeat
AhaeAN4_RS05645	COG0705	Rhomboid family
AhaeAN4_RS05665	COG1294	oxidase, subunit
AhaeAN4_RS05670	COG1271	oxidase subunit
AhaeAN4_RS05695	COG1215	transferase activity, transferring glycosyl groups
AhaeAN4_RS05710	COG0415	Belongs to the DNA photolyase family
AhaeAN4_RS05720	COG1252	NADH dehydrogenase
AhaeAN4_RS05725	COG1686	Belongs to the peptidase S11 family
AhaeAN4_RS05775	COG0384	phenazine biosynthesis protein PhzF
AhaeAN4_RS05780	COG0612	Peptidase, M16
AhaeAN4_RS05810	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN4_RS05830	COG0564	pseudouridine synthase activity
AhaeAN4_RS05840	COG0783	Belongs to the Dps family
AhaeAN4_RS05870	COG1309	transcriptional regulator
AhaeAN4_RS05880	COG4772	TonB-dependent receptor
AhaeAN4_RS05890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN4_RS05895	COG0076	glutamate decarboxylase activity
AhaeAN4_RS05910	COG0573	inorganic phosphate transmembrane transporter activity
AhaeAN4_RS05920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AhaeAN4_RS05925	COG0616	signal peptide processing
AhaeAN4_RS05950	COG0742	ribosomal rna small subunit methyltransferase
AhaeAN4_RS05955	COG0768	penicillin binding
AhaeAN4_RS05980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AhaeAN4_RS05985	COG2878	Part of a membrane complex involved in electron transport
AhaeAN4_RS05990	COG3501	Rhs element vgr protein
AhaeAN4_RS06020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN4_RS06030	COG3384	dioxygenase
AhaeAN4_RS06045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AhaeAN4_RS06055	COG0789	Transcriptional regulator
AhaeAN4_RS06060	COG4372	Transposase
AhaeAN4_RS06070	COG2963	transposase activity
AhaeAN4_RS06075	COG4372	Transposase
AhaeAN4_RS06085	COG2963	transposase activity
AhaeAN4_RS06090	COG2217	Heavy metal translocating P-type atpase
AhaeAN4_RS06460	COG0006	proline dipeptidase activity
AhaeAN4_RS06465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN4_RS06470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN4_RS06480	COG1279	arginine transmembrane transporter activity
AhaeAN4_RS06485	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS06515	COG2816	NAD+ diphosphatase activity
AhaeAN4_RS06525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AhaeAN4_RS06530	COG1388	LysM domain
AhaeAN4_RS06530	COG0741	lytic transglycosylase activity
AhaeAN4_RS06530	COG0741	lytic transglycosylase activity
AhaeAN4_RS06530	COG1388	LysM domain
AhaeAN4_RS06535	COG4166	transmembrane transport
AhaeAN4_RS06540	COG4174	ABC transporter (Permease)
AhaeAN4_RS06545	COG4239	(ABC) transporter, permease
AhaeAN4_RS06550	COG4172	Belongs to the ABC transporter superfamily
AhaeAN4_RS06565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AhaeAN4_RS06575	COG4251	negative regulation of phosphorylation
AhaeAN4_RS06575	COG3706	GGDEF domain
AhaeAN4_RS06575	COG2203	Gaf domain
AhaeAN4_RS06575	COG5001	Diguanylate cyclase
AhaeAN4_RS06590	COG3739	integral membrane protein
AhaeAN4_RS06610	COG0302	gtp cyclohydrolase
AhaeAN4_RS06625	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS06650	COG3217	Mosc domain protein beta barrel domain protein
AhaeAN4_RS06650	COG0633	Ferredoxin
AhaeAN4_RS06665	COG0512	Glutamine amidotransferase of anthranilate synthase
AhaeAN4_RS06675	COG3161	chorismate lyase activity
AhaeAN4_RS06680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AhaeAN4_RS06715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN4_RS06725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AhaeAN4_RS06730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AhaeAN4_RS06740	COG2223	nitrite transmembrane transporter activity
AhaeAN4_RS06755	COG0024	Methionine aminopeptidase
AhaeAN4_RS06760	COG0052	Belongs to the universal ribosomal protein uS2 family
AhaeAN4_RS06785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AhaeAN4_RS06790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AhaeAN4_RS06795	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AhaeAN4_RS06820	COG2011	ABC-type metal ion transport system permease component
AhaeAN4_RS06825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AhaeAN4_RS06830	COG1464	Belongs to the NlpA lipoprotein family
AhaeAN4_RS06835	COG0151	Belongs to the GarS family
AhaeAN4_RS06840	COG0138	bifunctional purine biosynthesis protein purh
AhaeAN4_RS06845	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AhaeAN4_RS06915	COG2252	PERMEase
AhaeAN4_RS06920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AhaeAN4_RS06925	COG3038	cytochrome b561
AhaeAN4_RS06935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AhaeAN4_RS06945	COG0527	aspartate kinase activity
AhaeAN4_RS06955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AhaeAN4_RS06975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AhaeAN4_RS06990	COG2308	Evidence 4 Homologs of previously reported genes of
AhaeAN4_RS07000	COG1305	Transglutaminase-like
AhaeAN4_RS07015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AhaeAN4_RS07020	COG0305	Participates in initiation and elongation during chromosome replication
AhaeAN4_RS07025	COG1733	regulation of RNA biosynthetic process
AhaeAN4_RS07030	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN4_RS07055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AhaeAN4_RS07060	COG1845	cytochrome c oxidase, subunit III
AhaeAN4_RS07065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AhaeAN4_RS07070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AhaeAN4_RS07090	COG3300	MHYT domain
AhaeAN4_RS07090	COG5001	Diguanylate cyclase
AhaeAN4_RS07095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AhaeAN4_RS07125	COG0802	atpase or kinase
AhaeAN4_RS07130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AhaeAN4_RS07140	COG1923	regulation of RNA biosynthetic process
AhaeAN4_RS07145	COG0697	spore germination
AhaeAN4_RS07155	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN4_RS07165	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN4_RS07175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AhaeAN4_RS07190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AhaeAN4_RS07205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AhaeAN4_RS07225	COG3634	alkyl hydroperoxide reductase activity
AhaeAN4_RS07245	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN4_RS07255	COG0450	alkyl hydroperoxide reductase
AhaeAN4_RS07260	COG1643	Atp-dependent helicase
AhaeAN4_RS07275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AhaeAN4_RS07300	COG2951	lytic endotransglycosylase activity
AhaeAN4_RS07305	COG0772	Belongs to the SEDS family
AhaeAN4_RS07320	COG0842	Transport permease protein
AhaeAN4_RS07325	COG1131	(ABC) transporter
AhaeAN4_RS07330	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS07340	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AhaeAN4_RS07350	COG3659	wide pore channel activity
AhaeAN4_RS07450	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS07480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AhaeAN4_RS07505	COG0729	surface antigen
AhaeAN4_RS07530	COG0471	metal ion transport
AhaeAN4_RS07535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AhaeAN4_RS07555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AhaeAN4_RS07560	COG4605	iron ion homeostasis
AhaeAN4_RS07565	COG4604	ABC transporter, ATP-binding protein
AhaeAN4_RS07570	COG4607	ABC-type enterochelin transport system periplasmic component
AhaeAN4_RS07575	COG2814	Major facilitator Superfamily
AhaeAN4_RS07585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AhaeAN4_RS07590	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS07625	COG1720	tRNA m6t6A37 methyltransferase activity
AhaeAN4_RS07650	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS07655	COG0642	Histidine kinase
AhaeAN4_RS07665	COG0494	nUDIX hydrolase
AhaeAN4_RS07675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AhaeAN4_RS07685	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AhaeAN4_RS07690	COG3139	Protein of unknown function (DUF1315)
AhaeAN4_RS07695	COG3501	Rhs element vgr protein
AhaeAN4_RS07715	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS07720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AhaeAN4_RS07725	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS07740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AhaeAN4_RS07800	COG3539	Fimbrial protein
AhaeAN4_RS07825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AhaeAN4_RS07825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AhaeAN4_RS07845	COG1278	Cold shock
AhaeAN4_RS07855	COG1278	Cold shock
AhaeAN4_RS07875	COG3042	response to heat
AhaeAN4_RS07890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AhaeAN4_RS07895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AhaeAN4_RS07920	COG2353	YceI-like domain
AhaeAN4_RS07925	COG3153	acetyltransferase
AhaeAN4_RS07940	COG3698	Phosphodiester glycosidase
AhaeAN4_RS07950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AhaeAN4_RS07960	COG0506	proline dehydrogenase activity
AhaeAN4_RS07960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AhaeAN4_RS07960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AhaeAN4_RS07970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AhaeAN4_RS07990	COG1132	(ABC) transporter
AhaeAN4_RS08045	COG0640	Transcriptional regulator
AhaeAN4_RS08085	COG2850	peptidyl-arginine hydroxylation
AhaeAN4_RS08105	COG4372	Transposase
AhaeAN4_RS08115	COG2963	transposase activity
AhaeAN4_RS08120	COG1454	alcohol dehydrogenase
AhaeAN4_RS08125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AhaeAN4_RS08145	COG0069	glutamate synthase activity
AhaeAN4_RS08160	COG2814	Major facilitator Superfamily
AhaeAN4_RS08175	COG0439	Biotin carboxylase
AhaeAN4_RS08190	COG1116	anion transmembrane transporter activity
AhaeAN4_RS08190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN4_RS08200	COG2223	nitrite transmembrane transporter activity
AhaeAN4_RS08205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN4_RS08205	COG2146	nitrite reductase [NAD(P)H] activity
AhaeAN4_RS08210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN4_RS08215	COG0243	molybdopterin cofactor binding
AhaeAN4_RS08225	COG3048	D-serine ammonia-lyase activity
AhaeAN4_RS08245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AhaeAN4_RS08260	COG0521	Mo-molybdopterin cofactor biosynthetic process
AhaeAN4_RS08260	COG0315	cyclic pyranopterin monophosphate synthase activity
AhaeAN4_RS08265	COG0303	'Molybdopterin
AhaeAN4_RS08285	COG0697	spore germination
AhaeAN4_RS08305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AhaeAN4_RS08355	COG1309	transcriptional regulator
AhaeAN4_RS08360	COG2204	response regulator
AhaeAN4_RS08365	COG3852	Histidine kinase
AhaeAN4_RS08375	COG0528	UMP kinase activity
AhaeAN4_RS08385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AhaeAN4_RS08390	COG0575	Belongs to the CDS family
AhaeAN4_RS08425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN4_RS08445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN4_RS08450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AhaeAN4_RS08455	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS08460	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS08505	COG2814	Major facilitator Superfamily
AhaeAN4_RS08520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AhaeAN4_RS08535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AhaeAN4_RS08540	COG0406	alpha-ribazole phosphatase activity
AhaeAN4_RS08560	COG4771	TonB-dependent receptor
AhaeAN4_RS08570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AhaeAN4_RS08575	COG0730	response to heat
AhaeAN4_RS08595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN4_RS08620	COG0537	adenosine 5'-monophosphoramidase activity
AhaeAN4_RS08660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AhaeAN4_RS08680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AhaeAN4_RS08700	COG3706	GGDEF domain
AhaeAN4_RS08710	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN4_RS08765	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS08775	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS08780	COG4774	siderophore transport
AhaeAN4_RS08790	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS08810	COG2814	Major facilitator Superfamily
AhaeAN4_RS08825	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN4_RS08830	COG1309	transcriptional regulator
AhaeAN4_RS08835	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS08840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AhaeAN4_RS08845	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS08860	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS08920	COG1595	DNA-templated transcription, initiation
AhaeAN4_RS08925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN4_RS08935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN4_RS08940	COG0864	Transcriptional regulator
AhaeAN4_RS08950	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS08960	COG0439	Biotin carboxylase
AhaeAN4_RS08975	COG1522	sequence-specific DNA binding
AhaeAN4_RS08990	COG2963	transposase activity
AhaeAN4_RS09000	COG4372	Transposase
AhaeAN4_RS09010	COG1944	ATP diphosphatase activity
AhaeAN4_RS09030	COG2207	Transcriptional regulator
AhaeAN4_RS09040	COG1802	Transcriptional regulator
AhaeAN4_RS09055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AhaeAN4_RS09065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AhaeAN4_RS09125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AhaeAN4_RS09130	COG0148	phosphopyruvate hydratase activity
AhaeAN4_RS09165	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN4_RS09165	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN4_RS09175	COG2267	carboxylic ester hydrolase activity
AhaeAN4_RS09180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AhaeAN4_RS09190	COG0542	response to heat
AhaeAN4_RS09195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AhaeAN4_RS09205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AhaeAN4_RS09240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AhaeAN4_RS09245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AhaeAN4_RS09250	COG0569	domain protein
AhaeAN4_RS09255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AhaeAN4_RS09275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AhaeAN4_RS09300	COG1294	oxidase, subunit
AhaeAN4_RS09305	COG4890	Cyd operon protein YbgT
AhaeAN4_RS09330	COG0552	protein localization to endoplasmic reticulum
AhaeAN4_RS09355	COG0517	IMP dehydrogenase activity
AhaeAN4_RS09355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AhaeAN4_RS09360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN4_RS09365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AhaeAN4_RS09375	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS09380	COG0024	Methionine aminopeptidase
AhaeAN4_RS09420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AhaeAN4_RS09425	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AhaeAN4_RS09440	COG2431	L-lysine efflux transmembrane transporter activity
AhaeAN4_RS09455	COG0776	regulation of translation
AhaeAN4_RS09475	COG0590	tRNA wobble adenosine to inosine editing
AhaeAN4_RS09520	COG0084	hydrolase, TatD family'
AhaeAN4_RS09545	COG1663	tetraacyldisaccharide 4'-kinase activity
AhaeAN4_RS09550	COG1132	(ABC) transporter
AhaeAN4_RS09560	COG0811	peptide transport
AhaeAN4_RS09565	COG1475	DNA binding
AhaeAN4_RS09570	COG1192	Involved in chromosome partitioning
AhaeAN4_RS09580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AhaeAN4_RS09595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AhaeAN4_RS09605	COG0513	Belongs to the DEAD box helicase family
AhaeAN4_RS09625	COG2363	Small membrane protein
AhaeAN4_RS09670	COG3550	peptidyl-serine autophosphorylation
AhaeAN4_RS09685	COG2195	Cleaves the N-terminal amino acid of tripeptides
AhaeAN4_RS09715	COG1464	Belongs to the NlpA lipoprotein family
AhaeAN4_RS09720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AhaeAN4_RS09725	COG2011	ABC-type metal ion transport system permease component
AhaeAN4_RS09730	COG0012	GTP binding
AhaeAN4_RS09740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AhaeAN4_RS09745	COG1253	flavin adenine dinucleotide binding
AhaeAN4_RS09770	COG0436	Aminotransferase
AhaeAN4_RS09780	COG1522	sequence-specific DNA binding
AhaeAN4_RS09790	COG0386	Belongs to the glutathione peroxidase family
AhaeAN4_RS09795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AhaeAN4_RS09800	COG0436	Aminotransferase
AhaeAN4_RS09840	COG3634	alkyl hydroperoxide reductase activity
AhaeAN4_RS09895	COG1286	toxin biosynthetic process
AhaeAN4_RS09950	COG0424	maF-like protein
AhaeAN4_RS09955	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS09960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AhaeAN4_RS10005	COG0183	Belongs to the thiolase family
AhaeAN4_RS10025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AhaeAN4_RS10030	COG0702	epimerase
AhaeAN4_RS10035	COG0268	Binds directly to 16S ribosomal RNA
AhaeAN4_RS10055	COG1218	3'(2'),5'-bisphosphate nucleotidase
AhaeAN4_RS10060	COG1011	Hydrolase
AhaeAN4_RS10065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AhaeAN4_RS10075	COG2137	regulation of response to DNA damage stimulus
AhaeAN4_RS10090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AhaeAN4_RS10095	COG0776	regulation of translation
AhaeAN4_RS10120	COG0822	iron-sulfur transferase activity
AhaeAN4_RS10125	COG0316	Belongs to the HesB IscA family
AhaeAN4_RS10155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AhaeAN4_RS10175	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS10190	COG3135	benzoate transporter
AhaeAN4_RS10195	COG0475	glutathione-regulated potassium exporter activity
AhaeAN4_RS10195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AhaeAN4_RS10205	COG1714	RDD family
AhaeAN4_RS10225	COG1760	l-serine dehydratase
AhaeAN4_RS10230	COG0308	aminopeptidase N
AhaeAN4_RS10260	COG4133	protoheme IX ABC transporter activity
AhaeAN4_RS10310	COG1765	OsmC-like protein
AhaeAN4_RS10320	COG0501	Belongs to the peptidase M48B family
AhaeAN4_RS10325	COG4770	biotin carboxylase activity
AhaeAN4_RS10330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AhaeAN4_RS10335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AhaeAN4_RS10340	COG1560	Kdo2-lipid A biosynthetic process
AhaeAN4_RS10345	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AhaeAN4_RS10350	COG2072	flavoprotein involved in K transport
AhaeAN4_RS10370	COG1309	transcriptional regulator
AhaeAN4_RS10390	COG0642	Histidine kinase
AhaeAN4_RS10395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AhaeAN4_RS10405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AhaeAN4_RS10425	COG3040	lipid binding
AhaeAN4_RS10430	COG5002	protein histidine kinase activity
AhaeAN4_RS10435	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS10440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN4_RS10445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN4_RS10450	COG1538	Outer membrane efflux protein
AhaeAN4_RS10460	COG2837	iron assimilation
AhaeAN4_RS10465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AhaeAN4_RS10470	COG0243	molybdopterin cofactor binding
AhaeAN4_RS10505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AhaeAN4_RS10510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN4_RS10515	COG0010	Belongs to the arginase family
AhaeAN4_RS10535	COG2188	Transcriptional regulator
AhaeAN4_RS10545	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS10560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN4_RS10570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN4_RS10585	COG4266	Belongs to the allantoicase family
AhaeAN4_RS10590	COG2186	Transcriptional regulator
AhaeAN4_RS10595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN4_RS10615	COG2233	PERMEase
AhaeAN4_RS10620	COG2351	hydroxyisourate hydrolase activity
AhaeAN4_RS10630	COG4993	Dehydrogenase
AhaeAN4_RS10635	COG3659	wide pore channel activity
AhaeAN4_RS10640	COG3420	alginic acid biosynthetic process
AhaeAN4_RS10645	COG0710	3-dehydroquinate dehydratase activity
AhaeAN4_RS10650	COG3485	protocatechuate 3,4-dioxygenase
AhaeAN4_RS10655	COG3485	protocatechuate 3,4-dioxygenase
AhaeAN4_RS10660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AhaeAN4_RS10665	COG2271	Major facilitator Superfamily
AhaeAN4_RS10670	COG0596	Alpha beta hydrolase
AhaeAN4_RS10675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AhaeAN4_RS10680	COG0183	Belongs to the thiolase family
AhaeAN4_RS10685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AhaeAN4_RS10690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AhaeAN4_RS10695	COG1414	Transcriptional regulator
AhaeAN4_RS10710	COG1469	GTP cyclohydrolase I activity
AhaeAN4_RS10715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AhaeAN4_RS10725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AhaeAN4_RS10760	COG2161	toxin-antitoxin pair type II binding
AhaeAN4_RS10765	COG4115	mRNA cleavage
AhaeAN4_RS10775	COG0582	viral genome integration into host DNA
AhaeAN4_RS10785	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN4_RS10785	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN4_RS10800	COG1741	Belongs to the pirin family
AhaeAN4_RS11170	COG0714	Associated with various cellular activities
AhaeAN4_RS11175	COG2879	small protein
AhaeAN4_RS11180	COG1966	Carbon starvation protein
AhaeAN4_RS11185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AhaeAN4_RS11190	COG1509	lysine 2,3-aminomutase activity
AhaeAN4_RS11205	COG0254	rRNA binding
AhaeAN4_RS11235	COG1067	ATP-dependent peptidase activity
AhaeAN4_RS11240	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS11250	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AhaeAN4_RS11270	COG1686	Belongs to the peptidase S11 family
AhaeAN4_RS11275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AhaeAN4_RS11290	COG0482	sulfurtransferase activity
AhaeAN4_RS11310	COG0028	Belongs to the TPP enzyme family
AhaeAN4_RS11380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AhaeAN4_RS11385	COG1610	YqeY-like protein
AhaeAN4_RS11405	COG4783	chaperone-mediated protein folding
AhaeAN4_RS11410	COG0204	Acyl-transferase
AhaeAN4_RS11435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AhaeAN4_RS11470	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS11495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AhaeAN4_RS11540	COG1137	ATPase activity
AhaeAN4_RS11545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AhaeAN4_RS11555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AhaeAN4_RS11560	COG0517	IMP dehydrogenase activity
AhaeAN4_RS11560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AhaeAN4_RS11680	COG3728	DNA packaging
AhaeAN4_RS11680	COG5484	DNA packaging
AhaeAN4_RS11775	COG3015	lipoprotein NlpE involved in copper resistance
AhaeAN4_RS11790	COG1253	flavin adenine dinucleotide binding
AhaeAN4_RS11795	COG0222	ribosome binding
AhaeAN4_RS11810	COG0175	sulfate reduction
AhaeAN4_RS11820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AhaeAN4_RS11830	COG1773	rubredoxin
AhaeAN4_RS11835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN4_RS11840	COG0596	Alpha beta hydrolase
AhaeAN4_RS11845	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS11870	COG1840	ABC-type Fe3 transport system, periplasmic component
AhaeAN4_RS11915	COG0556	nucleotide-excision repair
AhaeAN4_RS11965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AhaeAN4_RS11980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AhaeAN4_RS11985	COG0571	ribonuclease III activity
AhaeAN4_RS12000	COG0481	GTPase activity
AhaeAN4_RS12010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AhaeAN4_RS12025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AhaeAN4_RS12030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AhaeAN4_RS12035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AhaeAN4_RS12045	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AhaeAN4_RS12050	COG4208	sulfate ABC transporter
AhaeAN4_RS12055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AhaeAN4_RS12060	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS12075	COG0602	queuosine metabolic process
AhaeAN4_RS12080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AhaeAN4_RS12095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AhaeAN4_RS12115	COG1942	4-Oxalocrotonate Tautomerase
AhaeAN4_RS12120	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS12125	COG1051	belongs to the nudix hydrolase family
AhaeAN4_RS12125	COG1056	cytidyltransferase-related domain
AhaeAN4_RS12130	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS12135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AhaeAN4_RS12135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AhaeAN4_RS12140	COG1105	Belongs to the carbohydrate kinase PfkB family
AhaeAN4_RS12145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AhaeAN4_RS12145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AhaeAN4_RS12145	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AhaeAN4_RS12150	COG0778	Nitroreductase
AhaeAN4_RS12155	COG3323	Protein of unknown function (DUF1653)
AhaeAN4_RS12155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AhaeAN4_RS12175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AhaeAN4_RS12175	COG0047	phosphoribosylformylglycinamidine synthase activity
AhaeAN4_RS12190	COG2255	four-way junction helicase activity
AhaeAN4_RS12200	COG0824	Thioesterase
AhaeAN4_RS12220	COG0823	Involved in the tonB-independent uptake of proteins
AhaeAN4_RS12240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AhaeAN4_RS12280	COG0628	permease
AhaeAN4_RS12290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AhaeAN4_RS12300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AhaeAN4_RS12300	COG0616	signal peptide processing
AhaeAN4_RS12310	COG2333	competence protein COMEC
AhaeAN4_RS12310	COG0658	competence protein
AhaeAN4_RS12315	COG1136	(ABC) transporter
AhaeAN4_RS12320	COG4591	ABC-type transport system involved in lipoprotein release permease component
AhaeAN4_RS12335	COG1671	Belongs to the UPF0178 family
AhaeAN4_RS12365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN4_RS12375	COG0842	Transport permease protein
AhaeAN4_RS12390	COG2318	DinB family
AhaeAN4_RS12405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AhaeAN4_RS12410	COG1280	lysine exporter protein (LysE YggA)
AhaeAN4_RS12420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AhaeAN4_RS12425	COG0019	diaminopimelate decarboxylase activity
AhaeAN4_RS12435	COG1115	amino acid carrier protein
AhaeAN4_RS12465	COG2963	transposase activity
AhaeAN4_RS12475	COG4372	Transposase
AhaeAN4_RS12480	COG0306	phosphate transporter
AhaeAN4_RS12515	COG0242	peptide deformylase activity
AhaeAN4_RS12530	COG0589	response to stress
AhaeAN4_RS12555	COG2175	clavaminate synthase activity
AhaeAN4_RS12560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN4_RS12565	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AhaeAN4_RS12570	COG4521	taurine ABC transporter
AhaeAN4_RS12590	COG4149	molybdate abc transporter
AhaeAN4_RS12595	COG0725	ABC transporter, periplasmic molybdate-binding protein
AhaeAN4_RS12645	COG0174	glutamine synthetase
AhaeAN4_RS12650	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS12655	COG2205	protein histidine kinase activity
AhaeAN4_RS12660	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AhaeAN4_RS12665	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AhaeAN4_RS12670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AhaeAN4_RS12675	COG0569	domain protein
AhaeAN4_RS12680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AhaeAN4_RS12785	COG0582	viral genome integration into host DNA
AhaeAN4_RS12795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AhaeAN4_RS12800	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AhaeAN4_RS12815	COG0739	heme binding
AhaeAN4_RS12815	COG1196	nuclear chromosome segregation
AhaeAN4_RS12815	COG0741	lytic transglycosylase activity
AhaeAN4_RS12820	COG0501	Belongs to the peptidase M48B family
AhaeAN4_RS12830	COG2239	Acts as a magnesium transporter
AhaeAN4_RS12835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN4_RS12840	COG2194	sulfuric ester hydrolase activity
AhaeAN4_RS12845	COG0584	glycerophosphoryl diester phosphodiesterase
AhaeAN4_RS12870	COG2304	oxidoreductase activity
AhaeAN4_RS12880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AhaeAN4_RS12905	COG0505	Belongs to the CarA family
AhaeAN4_RS12920	COG2801	Transposase and inactivated derivatives
AhaeAN4_RS12930	COG0110	maltose O-acetyltransferase activity
AhaeAN4_RS12965	COG2321	neutral zinc metallopeptidase
AhaeAN4_RS12970	COG2354	Protein conserved in bacteria
AhaeAN4_RS12980	COG1585	Membrane protein implicated in regulation of membrane protease activity
AhaeAN4_RS12985	COG2268	Band 7 protein
AhaeAN4_RS13000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AhaeAN4_RS13020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AhaeAN4_RS13025	COG1053	succinate dehydrogenase
AhaeAN4_RS13030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AhaeAN4_RS13035	COG2009	succinate dehydrogenase
AhaeAN4_RS13060	COG0586	Pfam SNARE associated Golgi protein
AhaeAN4_RS13065	COG0500	methyltransferase
AhaeAN4_RS13075	COG1280	lysine exporter protein (LysE YggA)
AhaeAN4_RS13110	COG0321	lipoyl(octanoyl) transferase activity
AhaeAN4_RS13125	COG0531	amino acid
AhaeAN4_RS13135	COG1733	regulation of RNA biosynthetic process
AhaeAN4_RS13145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AhaeAN4_RS13150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AhaeAN4_RS13150	COG1648	precorrin-2 dehydrogenase activity
AhaeAN4_RS13165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AhaeAN4_RS13200	COG0671	phosphoesterase, PA-phosphatase related
AhaeAN4_RS13205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN4_RS13215	COG1538	Outer membrane efflux protein
AhaeAN4_RS13220	COG0393	Putative heavy-metal-binding
AhaeAN4_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN4_RS13250	COG0525	valine-tRNA ligase activity
AhaeAN4_RS13265	COG4372	Transposase
AhaeAN4_RS13275	COG2963	transposase activity
AhaeAN4_RS13290	COG2852	Protein conserved in bacteria
AhaeAN4_RS13305	COG0004	ammonium transporteR
AhaeAN4_RS13315	COG0765	amino acid transport
AhaeAN4_RS13320	COG0765	amino acid transport
AhaeAN4_RS13325	COG1126	abc transporter atp-binding protein
AhaeAN4_RS13335	COG0642	Histidine kinase
AhaeAN4_RS13340	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS13345	COG2194	sulfuric ester hydrolase activity
AhaeAN4_RS13375	COG1752	Esterase of the alpha-beta hydrolase superfamily
AhaeAN4_RS13390	COG0142	geranyltranstransferase activity
AhaeAN4_RS13400	COG1113	amino acid transport
AhaeAN4_RS13425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AhaeAN4_RS13435	COG0671	phosphoesterase, PA-phosphatase related
AhaeAN4_RS13455	COG0560	Phosphoserine phosphatase
AhaeAN4_RS13465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AhaeAN4_RS13475	COG1530	ribonuclease E activity
AhaeAN4_RS13480	COG0424	maF-like protein
AhaeAN4_RS13490	COG1792	Involved in formation and maintenance of cell shape
AhaeAN4_RS13495	COG1077	Cell shape determining protein MreB Mrl
AhaeAN4_RS13500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN4_RS13510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN4_RS13555	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AhaeAN4_RS13560	COG1752	Esterase of the alpha-beta hydrolase superfamily
AhaeAN4_RS13565	COG1115	amino acid carrier protein
AhaeAN4_RS13570	COG0786	glutamate:sodium symporter activity
AhaeAN4_RS13585	COG2814	Major facilitator Superfamily
AhaeAN4_RS13590	COG1289	transmembrane transporter activity
AhaeAN4_RS13645	COG1376	ErfK ybiS ycfS ynhG family protein
AhaeAN4_RS13650	COG2832	Protein of unknown function (DUF454)
AhaeAN4_RS13660	COG5510	response to toxic substance
AhaeAN4_RS13675	COG2198	Histidine kinase
AhaeAN4_RS13675	COG0643	Histidine kinase
AhaeAN4_RS13675	COG2198	Histidine kinase
AhaeAN4_RS13675	COG0643	Histidine kinase
AhaeAN4_RS13680	COG0840	transmembrane signaling receptor activity
AhaeAN4_RS13710	COG3422	double-strand break repair
AhaeAN4_RS13715	COG2824	Alkylphosphonate utilization operon protein PhnA
AhaeAN4_RS13725	COG0354	folic acid binding
AhaeAN4_RS13735	COG4772	TonB-dependent receptor
AhaeAN4_RS13760	COG2801	Transposase and inactivated derivatives
AhaeAN4_RS13765	COG2963	transposase activity
AhaeAN4_RS13775	COG4372	Transposase
AhaeAN4_RS13790	COG2233	PERMEase
AhaeAN4_RS13800	COG0833	amino acid
AhaeAN4_RS13805	COG1690	Belongs to the RtcB family
AhaeAN4_RS13810	COG2885	chlorophyll binding
AhaeAN4_RS13810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN4_RS13815	COG2885	chlorophyll binding
AhaeAN4_RS13815	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN4_RS13825	COG0183	Belongs to the thiolase family
AhaeAN4_RS13840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN4_RS13870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AhaeAN4_RS13875	COG2207	Transcriptional regulator
AhaeAN4_RS13885	COG0183	Belongs to the thiolase family
AhaeAN4_RS13890	COG1250	3-hydroxyacyl-CoA dehydrogenase
AhaeAN4_RS13890	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS13925	COG1272	protein, Hemolysin III
AhaeAN4_RS13930	COG0477	Major facilitator Superfamily
AhaeAN4_RS13950	COG0450	alkyl hydroperoxide reductase
AhaeAN4_RS13965	COG0285	dihydrofolate synthase activity
AhaeAN4_RS14005	COG0133	tryptophan synthase activity
AhaeAN4_RS14015	COG4206	TonB-dependent receptor
AhaeAN4_RS14020	COG2096	Adenosyltransferase
AhaeAN4_RS14040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AhaeAN4_RS14060	COG0745	RESPONSE REGULATOR receiver
AhaeAN4_RS14065	COG2205	protein histidine kinase activity
AhaeAN4_RS14075	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS14080	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS14120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AhaeAN4_RS14185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AhaeAN4_RS14195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AhaeAN4_RS14200	COG5002	protein histidine kinase activity
AhaeAN4_RS14200	COG2205	protein histidine kinase activity
AhaeAN4_RS14200	COG0784	Response regulator, receiver
AhaeAN4_RS14235	COG1862	Preprotein translocase
AhaeAN4_RS14245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AhaeAN4_RS14280	COG1426	Protein conserved in bacteria
AhaeAN4_RS14300	COG2975	iron-sulfur cluster assembly
AhaeAN4_RS14315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AhaeAN4_RS14320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AhaeAN4_RS14325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AhaeAN4_RS14335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AhaeAN4_RS14340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AhaeAN4_RS14345	COG0625	glutathione transferase activity
AhaeAN4_RS14350	COG2969	positive regulation of protein catabolic process
AhaeAN4_RS14405	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS14410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AhaeAN4_RS14425	COG1309	transcriptional regulator
AhaeAN4_RS14440	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS14480	COG2199	diguanylate cyclase activity
AhaeAN4_RS14490	COG1408	metallophosphoesterase
AhaeAN4_RS14495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AhaeAN4_RS14505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AhaeAN4_RS14525	COG0793	Belongs to the peptidase S41A family
AhaeAN4_RS14550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AhaeAN4_RS14555	COG0857	belongs to the CobB CobQ family
AhaeAN4_RS14555	COG0280	phosphate acetyltransferase
AhaeAN4_RS14585	COG0697	spore germination
AhaeAN4_RS14590	COG1917	Cupin 2, conserved barrel domain protein
AhaeAN4_RS14590	COG2207	Transcriptional regulator
AhaeAN4_RS14595	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AhaeAN4_RS14595	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AhaeAN4_RS14615	COG0740	serine-type endopeptidase activity
AhaeAN4_RS14625	COG4771	TonB-dependent receptor
AhaeAN4_RS14630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AhaeAN4_RS14640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AhaeAN4_RS14640	COG2813	Specifically methylates the guanine in position
AhaeAN4_RS14665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AhaeAN4_RS14695	COG1295	ribonuclease BN
AhaeAN4_RS14705	COG2207	Transcriptional regulator
AhaeAN4_RS14715	COG0179	Fumarylacetoacetate (FAA) hydrolase
AhaeAN4_RS14745	COG2963	transposase activity
AhaeAN4_RS14755	COG4372	Transposase
AhaeAN4_RS14805	COG0557	exoribonuclease II activity
AhaeAN4_RS14820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AhaeAN4_RS14835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AhaeAN4_RS14845	COG0644	oxidoreductase
AhaeAN4_RS14845	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AhaeAN4_RS14850	COG0425	Belongs to the sulfur carrier protein TusA family
AhaeAN4_RS14855	COG4535	Mg2 and Co2 transporter CorC
AhaeAN4_RS14860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AhaeAN4_RS14880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AhaeAN4_RS14890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AhaeAN4_RS14905	COG0789	Transcriptional regulator
AhaeAN4_RS14910	COG0598	Magnesium transport protein CorA
AhaeAN4_RS14915	COG1185	polyribonucleotide nucleotidyltransferase activity
AhaeAN4_RS14920	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AhaeAN4_RS14930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AhaeAN4_RS14935	COG1074	ATP-dependent DNA helicase activity
AhaeAN4_RS14940	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AhaeAN4_RS14965	COG2226	methyltransferase
AhaeAN4_RS14980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN4_RS14995	COG1116	anion transmembrane transporter activity
AhaeAN4_RS15000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN4_RS15010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AhaeAN4_RS15025	COG2111	Na H antiporter
AhaeAN4_RS15025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AhaeAN4_RS15030	COG1006	Multisubunit Na H antiporter MnhC subunit
AhaeAN4_RS15035	COG0651	ATP synthesis coupled electron transport
AhaeAN4_RS15045	COG2212	antiporter activity
AhaeAN4_RS15075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AhaeAN4_RS15085	COG0195	Participates in both transcription termination and antitermination
AhaeAN4_RS15135	COG0237	dephospho-CoA kinase activity
AhaeAN4_RS15145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AhaeAN4_RS15155	COG0497	DNA recombination
AhaeAN4_RS15165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AhaeAN4_RS15190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AhaeAN4_RS15245	COG1132	(ABC) transporter
AhaeAN4_RS15260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AhaeAN4_RS15275	COG0326	Molecular chaperone. Has ATPase activity
AhaeAN4_RS15285	COG2056	Na+-H+ antiporter family
AhaeAN4_RS15335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AhaeAN4_RS15345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AhaeAN4_RS15355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AhaeAN4_RS15385	COG0546	phosphoglycolate phosphatase activity
AhaeAN4_RS15435	COG0181	hydroxymethylbilane synthase activity
AhaeAN4_RS15450	COG3275	phosphorelay sensor kinase activity
AhaeAN4_RS15475	COG0494	nUDIX hydrolase
AhaeAN4_RS15485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AhaeAN4_RS15490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AhaeAN4_RS15495	COG0772	Belongs to the SEDS family
AhaeAN4_RS15520	COG4974	Belongs to the 'phage' integrase family
AhaeAN4_RS15525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AhaeAN4_RS15535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AhaeAN4_RS15540	COG1686	Belongs to the peptidase S11 family
AhaeAN4_RS15545	COG2197	response regulator
AhaeAN4_RS15560	COG0793	Belongs to the peptidase S41A family
AhaeAN4_RS15565	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AhaeAN4_RS15570	COG0795	lipopolysaccharide-transporting ATPase activity
AhaeAN4_RS15575	COG0795	lipopolysaccharide-transporting ATPase activity
AhaeAN4_RS15610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AhaeAN4_RS15610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AhaeAN4_RS15615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AhaeAN4_RS15620	COG0004	ammonium transporteR
AhaeAN4_RS15625	COG0347	Belongs to the P(II) protein family
AhaeAN4_RS15700	COG1538	Outer membrane efflux protein
AhaeAN4_RS15710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN4_RS15715	COG1230	cation diffusion facilitator family transporter
AhaeAN4_RS15725	COG2963	transposase activity
AhaeAN4_RS15735	COG4372	Transposase
AhaeAN4_RS15740	COG0640	Transcriptional regulator
AhaeAN4_RS15750	COG0789	Transcriptional regulator
AhaeAN4_RS15780	COG2814	Major facilitator Superfamily
AhaeAN4_RS15825	COG0633	Ferredoxin
AhaeAN4_RS15880	COG0606	chelatase, subunit chli
AhaeAN4_RS15915	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN4_RS15930	COG2860	membrane
AhaeAN4_RS15940	COG1253	flavin adenine dinucleotide binding
AhaeAN4_RS15955	COG2814	Major facilitator Superfamily
AhaeAN4_RS15965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AhaeAN4_RS15990	COG2814	Major facilitator Superfamily
AhaeAN4_RS16000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AhaeAN4_RS16005	COG1283	sodium-dependent phosphate transmembrane transporter activity
AhaeAN4_RS16035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AhaeAN4_RS16050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AhaeAN4_RS16055	COG3162	membrane
AhaeAN4_RS16060	COG2205	protein histidine kinase activity
AhaeAN4_RS16085	COG1652	LysM domain
AhaeAN4_RS16090	COG0758	DNA mediated transformation
AhaeAN4_RS16105	COG1309	transcriptional regulator
AhaeAN4_RS16115	COG2814	Major facilitator Superfamily
AhaeAN4_RS16125	COG0386	Belongs to the glutathione peroxidase family
AhaeAN4_RS16140	COG3328	transposase activity
AhaeAN4_RS16155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AhaeAN4_RS16165	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AhaeAN4_RS16205	COG1121	(ABC) transporter
AhaeAN4_RS16210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AhaeAN4_RS16215	COG1280	lysine exporter protein (LysE YggA)
AhaeAN4_RS16220	COG2837	iron assimilation
AhaeAN4_RS16255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN4_RS16260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AhaeAN4_RS16275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AhaeAN4_RS16275	COG0519	Catalyzes the synthesis of GMP from XMP
AhaeAN4_RS16280	COG4399	Belongs to the UPF0754 family
AhaeAN4_RS16290	COG2259	Doxx family
AhaeAN4_RS16295	COG0586	Pfam SNARE associated Golgi protein
AhaeAN4_RS16310	COG1192	Involved in chromosome partitioning
AhaeAN4_RS16320	COG0271	Belongs to the BolA IbaG family
AhaeAN4_RS16355	COG3756	Protein conserved in bacteria
AhaeAN4_RS16380	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS16395	COG2304	oxidoreductase activity
AhaeAN4_RS16470	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN4_RS16580	COG0735	belongs to the Fur family
AhaeAN4_RS16650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AhaeAN4_RS16660	COG4115	mRNA cleavage
AhaeAN4_RS16675	COG0477	Major facilitator Superfamily
AhaeAN4_RS16680	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS16685	COG1024	Enoyl-CoA hydratase
AhaeAN4_RS16690	COG1960	acyl-CoA dehydrogenase activity
AhaeAN4_RS16695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AhaeAN4_RS16715	COG1113	amino acid transport
AhaeAN4_RS16720	COG0251	oxidation-reduction process
AhaeAN4_RS16735	COG1522	sequence-specific DNA binding
AhaeAN4_RS16750	COG0456	acetyltransferase
AhaeAN4_RS16755	COG0564	pseudouridine synthase activity
AhaeAN4_RS16760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AhaeAN4_RS16785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AhaeAN4_RS16800	COG1802	Transcriptional regulator
AhaeAN4_RS16810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AhaeAN4_RS16815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AhaeAN4_RS16830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AhaeAN4_RS16840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AhaeAN4_RS16850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AhaeAN4_RS16870	COG1045	serine acetyltransferase
AhaeAN4_RS16900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AhaeAN4_RS16935	COG3023	N-Acetylmuramoyl-L-alanine amidase
AhaeAN4_RS16990	COG0546	phosphoglycolate phosphatase activity
AhaeAN4_RS16995	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN4_RS17005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AhaeAN4_RS17005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AhaeAN4_RS17010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN4_RS17015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN4_RS17020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AhaeAN4_RS17025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN4_RS17030	COG1116	anion transmembrane transporter activity
AhaeAN4_RS17035	COG1309	transcriptional regulator
AhaeAN4_RS17060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AhaeAN4_RS17070	COG0196	riboflavin kinase activity
AhaeAN4_RS17075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AhaeAN4_RS17085	COG1047	Peptidyl-prolyl cis-trans
AhaeAN4_RS17125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AhaeAN4_RS17150	COG0583	DNA-binding transcription factor activity
AhaeAN4_RS17160	COG0443	Heat shock 70 kDa protein
AhaeAN4_RS17165	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AhaeAN4_RS17195	COG2951	lytic endotransglycosylase activity
AhaeAN4_RS17205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AhaeAN4_RS17225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AhaeAN4_RS17255	COG0861	Integral membrane protein TerC family
AhaeAN4_RS17260	COG0402	S-adenosylhomocysteine deaminase activity
AhaeAN4_RS17275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AhaeAN4_RS17285	COG0706	membrane insertase activity
AhaeAN4_RS17300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AhaeAN4_RS17335	COG3316	Transposase and inactivated derivatives
AhaeAN4_RS17340	COG1063	alcohol dehydrogenase
AhaeAN4_RS17345	COG4716	Myosin-crossreactive antigen
AhaeAN4_RS17400	COG3316	Transposase and inactivated derivatives
AhaeAN4_RS17410	COG2801	Transposase and inactivated derivatives
AhaeAN4_RS17445	COG0582	viral genome integration into host DNA
AhaeAN4_RS17540	COG1570	exodeoxyribonuclease VII activity
AhaeAN4_RS17560	COG1877	trehalose-phosphatase activity
AhaeAN4_RS17565	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AhaeAN4_RS17570	COG2223	nitrite transmembrane transporter activity
AhaeAN4_RS17615	COG2323	membrane
AhaeAN4_RS17630	COG1063	alcohol dehydrogenase
AhaeAN4_RS17645	COG4680	protein conserved in bacteria
AhaeAN4_RS17675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AhaeAN4_RS17680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AhaeAN4_RS17715	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AhaeAN4_RS17725	COG0402	S-adenosylhomocysteine deaminase activity
AhaeAN4_RS17745	COG3316	Transposase and inactivated derivatives
AhaeAN4_RS17755	COG4680	protein conserved in bacteria
AhaeAN4_RS17760	COG1373	ATPase (AAA superfamily
AhaeAN4_RS17780	COG3316	Transposase and inactivated derivatives
AhaeAN4_RS17785	COG0789	Transcriptional regulator
AhaeAN4_RS17880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AhaeAN4_RS17925	COG2337	Toxic component of a toxin-antitoxin (TA) module
AhaeAN4_RS17930	COG2336	PFAM SpoVT AbrB