locus-tag	class	description
BSR56_RS00010	COG0592	DNA-directed DNA polymerase activity
BSR56_RS00020	COG0187	DNA topoisomerase II activity
BSR56_RS00025	COG0586	Pfam SNARE associated Golgi protein
BSR56_RS00030	COG0488	(ABC) transporter
BSR56_RS00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSR56_RS00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSR56_RS00100	COG0471	metal ion transport
BSR56_RS00100	COG3273	potassium ion transport
BSR56_RS00110	COG1012	belongs to the aldehyde dehydrogenase family
BSR56_RS00115	COG3738	Protein conserved in bacteria
BSR56_RS00125	COG0733	neurotransmitter:sodium symporter activity
BSR56_RS00165	COG2233	PERMEase
BSR56_RS00185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR56_RS00200	COG0484	heat shock protein binding
BSR56_RS00215	COG2814	Major facilitator Superfamily
BSR56_RS00220	COG0656	L-ascorbic acid biosynthetic process
BSR56_RS00225	COG0583	DNA-binding transcription factor activity
BSR56_RS00240	COG1064	alcohol dehydrogenase
BSR56_RS00245	COG2818	Glycosylase
BSR56_RS00260	COG1194	a g-specific adenine glycosylase
BSR56_RS00275	COG5487	UPF0391 membrane protein
BSR56_RS00280	COG2983	Belongs to the UPF0260 family
BSR56_RS00285	COG2133	pyrroloquinoline quinone binding
BSR56_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSR56_RS00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSR56_RS00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSR56_RS00320	COG1335	isochorismatase
BSR56_RS00325	COG1522	sequence-specific DNA binding
BSR56_RS00335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSR56_RS00345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BSR56_RS00350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSR56_RS00355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSR56_RS00375	COG3830	Belongs to the UPF0237 family
BSR56_RS00375	COG0560	Phosphoserine phosphatase
BSR56_RS00400	COG0753	catalase activity
BSR56_RS00430	COG1278	Cold shock
BSR56_RS00480	COG0436	Aminotransferase
BSR56_RS00490	COG2733	membrane
BSR56_RS00505	COG2918	glutathione biosynthetic process
BSR56_RS00520	COG3150	esterase
BSR56_RS00560	COG1247	-acetyltransferase
BSR56_RS00565	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS00595	COG0625	glutathione transferase activity
BSR56_RS00615	COG1393	Belongs to the ArsC family
BSR56_RS00620	COG0708	Exodeoxyribonuclease III
BSR56_RS00645	COG0300	oxidoreductase activity
BSR56_RS00685	COG0386	Belongs to the glutathione peroxidase family
BSR56_RS00690	COG0189	ligase activity
BSR56_RS00710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSR56_RS00720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSR56_RS00745	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSR56_RS00755	COG2119	membrane
BSR56_RS00765	COG0426	domain, Protein
BSR56_RS00765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSR56_RS00790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSR56_RS00815	COG1902	pentaerythritol trinitrate reductase activity
BSR56_RS00820	COG1519	Transferase
BSR56_RS00830	COG0668	transmembrane transport
BSR56_RS00835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSR56_RS00865	COG3706	GGDEF domain
BSR56_RS00890	COG0351	phosphomethylpyrimidine kinase
BSR56_RS00890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BSR56_RS00890	COG0352	thiamine-phosphate diphosphorylase activity
BSR56_RS00900	COG2814	Major facilitator Superfamily
BSR56_RS00935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSR56_RS00940	COG1012	belongs to the aldehyde dehydrogenase family
BSR56_RS00950	COG1335	isochorismatase
BSR56_RS00960	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BSR56_RS01005	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS01040	COG3158	transport of potassium into the cell
BSR56_RS01070	COG0107	imidazoleglycerol-phosphate synthase activity
BSR56_RS01075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSR56_RS01095	COG0659	secondary active sulfate transmembrane transporter activity
BSR56_RS01120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSR56_RS01155	COG0427	acetyl-CoA hydrolase
BSR56_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
BSR56_RS01200	COG0583	DNA-binding transcription factor activity
BSR56_RS01210	COG0789	Transcriptional regulator
BSR56_RS01215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSR56_RS01215	COG3320	Male sterility
BSR56_RS01220	COG4221	oxidoreductase activity
BSR56_RS01225	COG2873	o-acetylhomoserine
BSR56_RS01230	COG0488	(ABC) transporter
BSR56_RS01305	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS01355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSR56_RS01365	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS01405	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS01410	COG0582	viral genome integration into host DNA
BSR56_RS01415	COG0582	viral genome integration into host DNA
BSR56_RS01495	COG0833	amino acid
BSR56_RS01520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSR56_RS01540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSR56_RS01545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BSR56_RS01550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSR56_RS01555	COG2226	methyltransferase
BSR56_RS01605	COG0067	glutamate synthase
BSR56_RS01605	COG0069	glutamate synthase activity
BSR56_RS01605	COG0070	glutamate synthase
BSR56_RS01610	COG0493	'glutamate synthase
BSR56_RS01630	COG1704	LemA family
BSR56_RS01635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BSR56_RS01650	COG1487	ribonuclease activity
BSR56_RS01700	COG3620	sequence-specific DNA binding
BSR56_RS01765	COG4636	protein conserved in cyanobacteria
BSR56_RS01770	COG3307	-O-antigen
BSR56_RS01790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSR56_RS01800	COG0194	GDP metabolic process
BSR56_RS01805	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSR56_RS01810	COG4969	Belongs to the N-Me-Phe pilin family
BSR56_RS01845	COG0228	four-way junction DNA binding
BSR56_RS01850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSR56_RS01860	COG0335	large ribosomal subunit rRNA binding
BSR56_RS01870	COG5380	lipid catabolic process
BSR56_RS01875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSR56_RS01905	COG0739	heme binding
BSR56_RS01905	COG0741	lytic transglycosylase activity
BSR56_RS01905	COG1196	nuclear chromosome segregation
BSR56_RS01910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSR56_RS01915	COG0277	FAD linked oxidase domain protein
BSR56_RS01930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BSR56_RS01935	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSR56_RS01955	COG0628	permease
BSR56_RS01960	COG1192	Involved in chromosome partitioning
BSR56_RS01970	COG2226	methyltransferase
BSR56_RS02010	COG2072	flavoprotein involved in K transport
BSR56_RS02050	COG0471	metal ion transport
BSR56_RS02060	COG1983	PspC domain protein
BSR56_RS02070	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS02100	COG0408	coproporphyrinogen oxidase activity
BSR56_RS02125	COG1127	ABC transporter
BSR56_RS02130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSR56_RS02135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BSR56_RS02140	COG2854	intermembrane phospholipid transfer
BSR56_RS02155	COG0598	Magnesium transport protein CorA
BSR56_RS02170	COG1040	competence protein
BSR56_RS02175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSR56_RS02190	COG2937	Belongs to the GPAT DAPAT family
BSR56_RS02195	COG1946	Acyl-CoA thioesterase
BSR56_RS02200	COG1301	dicarboxylic acid transport
BSR56_RS02220	COG1959	2 iron, 2 sulfur cluster binding
BSR56_RS02230	COG0433	COG0433 Predicted ATPase
BSR56_RS02250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSR56_RS02270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSR56_RS02400	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS02405	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BSR56_RS02430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSR56_RS02450	COG0339	signal peptide processing
BSR56_RS02455	COG0557	exoribonuclease II activity
BSR56_RS02510	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSR56_RS02515	COG2207	Transcriptional regulator
BSR56_RS02525	COG1295	ribonuclease BN
BSR56_RS02555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSR56_RS02590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSR56_RS02590	COG2813	Specifically methylates the guanine in position
BSR56_RS02600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSR56_RS02610	COG3128	pkhd-type hydroxylase
BSR56_RS02620	COG4771	TonB-dependent receptor
BSR56_RS02630	COG0740	serine-type endopeptidase activity
BSR56_RS02650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BSR56_RS02650	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BSR56_RS02655	COG2207	Transcriptional regulator
BSR56_RS02655	COG1917	Cupin 2, conserved barrel domain protein
BSR56_RS02660	COG0697	spore germination
BSR56_RS02670	COG0280	phosphate acetyltransferase
BSR56_RS02670	COG0857	belongs to the CobB CobQ family
BSR56_RS02675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSR56_RS02700	COG0793	Belongs to the peptidase S41A family
BSR56_RS02720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSR56_RS02730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSR56_RS02735	COG1408	metallophosphoesterase
BSR56_RS02745	COG2199	diguanylate cyclase activity
BSR56_RS02810	COG1607	acyl-coa hydrolase
BSR56_RS02815	COG1956	GAF domain-containing protein
BSR56_RS02830	COG1666	GTP binding
BSR56_RS02865	COG3781	membrane
BSR56_RS02875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSR56_RS02900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSR56_RS02910	COG1162	GTPase activity
BSR56_RS02915	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BSR56_RS02945	COG1538	Outer membrane efflux protein
BSR56_RS02950	COG0577	efflux transmembrane transporter activity
BSR56_RS02950	COG1136	(ABC) transporter
BSR56_RS02955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR56_RS02960	COG1466	dna polymerase III delta subunit
BSR56_RS02980	COG0028	Belongs to the TPP enzyme family
BSR56_RS02985	COG0440	acetolactate synthase activity
BSR56_RS02990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSR56_RS03025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSR56_RS03035	COG0726	polysaccharide deacetylase
BSR56_RS03040	COG0084	hydrolase, TatD family'
BSR56_RS03050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BSR56_RS03060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSR56_RS03070	COG0640	Transcriptional regulator
BSR56_RS03080	COG0798	PFAM Bile acid sodium symporter
BSR56_RS03095	COG0456	acetyltransferase
BSR56_RS03105	COG1917	Cupin 2, conserved barrel domain protein
BSR56_RS03110	COG5285	phytanoyl-CoA dioxygenase
BSR56_RS03115	COG2814	Major facilitator Superfamily
BSR56_RS03160	COG3622	Belongs to the hyi family
BSR56_RS03165	COG2084	Dehydrogenase
BSR56_RS03170	COG1024	Enoyl-CoA hydratase
BSR56_RS03175	COG0784	Response regulator, receiver
BSR56_RS03175	COG2205	protein histidine kinase activity
BSR56_RS03175	COG5002	protein histidine kinase activity
BSR56_RS03195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSR56_RS03215	COG3956	TIGRFAM MazG family protein
BSR56_RS03220	COG1555	photosystem II stabilization
BSR56_RS03225	COG0617	tRNA 3'-terminal CCA addition
BSR56_RS03230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSR56_RS03255	COG3028	Belongs to the UPF0307 family
BSR56_RS03260	COG0318	PFAM AMP-dependent synthetase and ligase
BSR56_RS03280	COG0625	glutathione transferase activity
BSR56_RS03295	COG1238	metal cluster binding
BSR56_RS03330	COG0072	phenylalanine-tRNA ligase activity
BSR56_RS03355	COG0248	Ppx GppA phosphatase
BSR56_RS03365	COG0037	tRNA processing
BSR56_RS03380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSR56_RS03380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSR56_RS03405	COG1764	response to oxidative stress
BSR56_RS03415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSR56_RS03460	COG0471	metal ion transport
BSR56_RS03460	COG3273	potassium ion transport
BSR56_RS03485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSR56_RS03490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSR56_RS03495	COG1595	DNA-templated transcription, initiation
BSR56_RS03505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSR56_RS03530	COG0494	nUDIX hydrolase
BSR56_RS03540	COG1214	PFAM Peptidase M22, glycoprotease
BSR56_RS03545	COG1968	undecaprenyl-diphosphatase activity
BSR56_RS03570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSR56_RS03580	COG2132	Multicopper oxidase
BSR56_RS03600	COG2076	Multidrug Resistance protein
BSR56_RS03605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSR56_RS03610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSR56_RS03650	COG1063	alcohol dehydrogenase
BSR56_RS03670	COG1309	transcriptional regulator
BSR56_RS03675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BSR56_RS03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BSR56_RS03690	COG2814	Major facilitator Superfamily
BSR56_RS03715	COG0625	glutathione transferase activity
BSR56_RS03725	COG1113	amino acid transport
BSR56_RS03745	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS03750	COG5290	Psort location Cytoplasmic, score
BSR56_RS03755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSR56_RS03775	COG0745	RESPONSE REGULATOR receiver
BSR56_RS03780	COG2205	protein histidine kinase activity
BSR56_RS03795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSR56_RS03805	COG0649	NAD binding
BSR56_RS03805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSR56_RS03815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSR56_RS03830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSR56_RS03850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSR56_RS03870	COG0583	DNA-binding transcription factor activity
BSR56_RS03890	COG0668	transmembrane transport
BSR56_RS03895	COG2081	HI0933 family
BSR56_RS03900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BSR56_RS03920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BSR56_RS03930	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS03940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR56_RS03940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR56_RS03975	COG0489	protein tyrosine kinase activity
BSR56_RS03995	COG2358	TRAP transporter, solute receptor (TAXI family
BSR56_RS04070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSR56_RS04090	COG0730	response to heat
BSR56_RS04100	COG1196	nuclear chromosome segregation
BSR56_RS04115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSR56_RS04130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSR56_RS04135	COG2226	methyltransferase
BSR56_RS04135	COG0596	Alpha beta hydrolase
BSR56_RS04135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSR56_RS04150	COG4106	trans-aconitate 2-methyltransferase activity
BSR56_RS04195	COG0747	negative chemotaxis
BSR56_RS04225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSR56_RS04230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSR56_RS04245	COG0009	L-threonylcarbamoyladenylate synthase
BSR56_RS04250	COG3101	peptidyl-lysine hydroxylation
BSR56_RS04255	COG1399	metal-binding, possibly nucleic acid-binding protein
BSR56_RS04260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSR56_RS04285	COG1652	LysM domain
BSR56_RS04290	COG0351	phosphomethylpyrimidine kinase
BSR56_RS04290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BSR56_RS04290	COG0352	thiamine-phosphate diphosphorylase activity
BSR56_RS04300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSR56_RS04335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSR56_RS04365	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BSR56_RS04380	COG0358	DNA primase activity
BSR56_RS04390	COG0564	pseudouridine synthase activity
BSR56_RS04395	COG1496	oxidoreductase activity
BSR56_RS04500	COG2205	protein histidine kinase activity
BSR56_RS04515	COG2132	Multicopper oxidase
BSR56_RS04575	COG0582	viral genome integration into host DNA
BSR56_RS04585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BSR56_RS04610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSR56_RS04610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSR56_RS04625	COG1981	membrane
BSR56_RS04645	COG0049	tRNA binding
BSR56_RS04655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSR56_RS04670	COG0456	acetyltransferase
BSR56_RS04680	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSR56_RS04685	COG0492	ferredoxin-NADP+ reductase activity
BSR56_RS04690	COG1674	ftsk spoiiie
BSR56_RS04690	COG0531	amino acid
BSR56_RS04695	COG1280	lysine exporter protein (LysE YggA)
BSR56_RS04705	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BSR56_RS04710	COG2894	cell division
BSR56_RS04715	COG0850	regulation of cytokinetic process
BSR56_RS04725	COG0204	Acyl-transferase
BSR56_RS04730	COG2885	chlorophyll binding
BSR56_RS04735	COG0210	DNA helicase
BSR56_RS04740	COG0756	dUTP diphosphatase activity
BSR56_RS04745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSR56_RS04760	COG0121	glutamine amidotransferase
BSR56_RS04775	COG2914	Belongs to the UPF0125 (RnfH) family
BSR56_RS04780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSR56_RS04810	COG0420	3'-5' exonuclease activity
BSR56_RS04835	COG1090	epimerase
BSR56_RS04840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSR56_RS04850	COG2050	protein possibly involved in aromatic compounds catabolism
BSR56_RS04855	COG1566	PFAM secretion protein HlyD family protein
BSR56_RS04860	COG2814	Major facilitator Superfamily
BSR56_RS04885	COG0625	glutathione transferase activity
BSR56_RS04910	COG1454	alcohol dehydrogenase
BSR56_RS04915	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS04925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSR56_RS04930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSR56_RS04940	COG1012	belongs to the aldehyde dehydrogenase family
BSR56_RS04955	COG0833	amino acid
BSR56_RS04960	COG0281	malic enzyme
BSR56_RS04975	COG1607	acyl-coa hydrolase
BSR56_RS04985	COG0523	cobalamin synthesis protein
BSR56_RS04990	COG4681	YaeQ
BSR56_RS05045	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BSR56_RS05055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BSR56_RS05120	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS05135	COG3152	Membrane
BSR56_RS05160	COG2388	GCN5-related N-acetyl-transferase
BSR56_RS05170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSR56_RS05200	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BSR56_RS05205	COG1597	lipid kinase activity
BSR56_RS05210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BSR56_RS05240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BSR56_RS05275	COG3293	Transposase
BSR56_RS05300	COG0456	acetyltransferase
BSR56_RS05310	COG4181	ATPase activity
BSR56_RS05315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BSR56_RS05345	COG1294	oxidase, subunit
BSR56_RS05350	COG1271	oxidase subunit
BSR56_RS05370	COG0415	Belongs to the DNA photolyase family
BSR56_RS05380	COG1252	NADH dehydrogenase
BSR56_RS05385	COG1686	Belongs to the peptidase S11 family
BSR56_RS05420	COG0384	phenazine biosynthesis protein PhzF
BSR56_RS05425	COG0612	Peptidase, M16
BSR56_RS05455	COG0352	thiamine-phosphate diphosphorylase activity
BSR56_RS05480	COG0564	pseudouridine synthase activity
BSR56_RS05490	COG0783	Belongs to the Dps family
BSR56_RS05520	COG1309	transcriptional regulator
BSR56_RS05530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSR56_RS05555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSR56_RS05560	COG0616	signal peptide processing
BSR56_RS05585	COG0742	ribosomal rna small subunit methyltransferase
BSR56_RS05590	COG0768	penicillin binding
BSR56_RS05615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSR56_RS05620	COG2878	Part of a membrane complex involved in electron transport
BSR56_RS05650	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS05660	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS05665	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS05685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSR56_RS05700	COG3384	dioxygenase
BSR56_RS05715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSR56_RS05735	COG2217	Heavy metal translocating P-type atpase
BSR56_RS05765	COG0006	proline dipeptidase activity
BSR56_RS05775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSR56_RS05780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSR56_RS05825	COG2816	NAD+ diphosphatase activity
BSR56_RS05835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSR56_RS05840	COG0741	lytic transglycosylase activity
BSR56_RS05840	COG1388	LysM domain
BSR56_RS05840	COG1388	LysM domain
BSR56_RS05840	COG0741	lytic transglycosylase activity
BSR56_RS05845	COG4166	transmembrane transport
BSR56_RS05850	COG4174	ABC transporter (Permease)
BSR56_RS05855	COG4239	(ABC) transporter, permease
BSR56_RS05860	COG4172	Belongs to the ABC transporter superfamily
BSR56_RS05870	COG0582	viral genome integration into host DNA
BSR56_RS05925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSR56_RS05935	COG4251	negative regulation of phosphorylation
BSR56_RS05935	COG2203	Gaf domain
BSR56_RS05935	COG5001	Diguanylate cyclase
BSR56_RS05935	COG3706	GGDEF domain
BSR56_RS05950	COG3739	integral membrane protein
BSR56_RS05970	COG0302	gtp cyclohydrolase
BSR56_RS05995	COG3217	Mosc domain protein beta barrel domain protein
BSR56_RS05995	COG0633	Ferredoxin
BSR56_RS06000	COG1823	symporter activity
BSR56_RS06005	COG0512	Glutamine amidotransferase of anthranilate synthase
BSR56_RS06010	COG0174	glutamine synthetase
BSR56_RS06025	COG2852	Protein conserved in bacteria
BSR56_RS06030	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BSR56_RS06035	COG3161	chorismate lyase activity
BSR56_RS06040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSR56_RS06075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSR56_RS06080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSR56_RS06085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSR56_RS06095	COG2223	nitrite transmembrane transporter activity
BSR56_RS06110	COG0024	Methionine aminopeptidase
BSR56_RS06115	COG0052	Belongs to the universal ribosomal protein uS2 family
BSR56_RS06140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSR56_RS06145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSR56_RS06150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSR56_RS06185	COG2011	ABC-type metal ion transport system permease component
BSR56_RS06190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BSR56_RS06195	COG1464	Belongs to the NlpA lipoprotein family
BSR56_RS06200	COG0151	Belongs to the GarS family
BSR56_RS06205	COG0138	bifunctional purine biosynthesis protein purh
BSR56_RS06210	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BSR56_RS06255	COG2252	PERMEase
BSR56_RS06260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSR56_RS06265	COG3038	cytochrome b561
BSR56_RS06280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSR56_RS06290	COG0527	aspartate kinase activity
BSR56_RS06300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSR56_RS06315	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSR56_RS06325	COG2308	Evidence 4 Homologs of previously reported genes of
BSR56_RS06335	COG1305	Transglutaminase-like
BSR56_RS06350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSR56_RS06355	COG0305	Participates in initiation and elongation during chromosome replication
BSR56_RS06360	COG1733	regulation of RNA biosynthetic process
BSR56_RS06365	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSR56_RS06390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSR56_RS06395	COG1845	cytochrome c oxidase, subunit III
BSR56_RS06400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSR56_RS06405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSR56_RS06425	COG3300	MHYT domain
BSR56_RS06425	COG5001	Diguanylate cyclase
BSR56_RS06430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSR56_RS06460	COG0802	atpase or kinase
BSR56_RS06465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSR56_RS06475	COG1923	regulation of RNA biosynthetic process
BSR56_RS06480	COG0697	spore germination
BSR56_RS06485	COG0778	Nitroreductase
BSR56_RS06490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSR56_RS06500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSR56_RS06505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSR56_RS06505	COG0519	Catalyzes the synthesis of GMP from XMP
BSR56_RS06515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSR56_RS06530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSR56_RS06550	COG3634	alkyl hydroperoxide reductase activity
BSR56_RS06570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSR56_RS06580	COG0450	alkyl hydroperoxide reductase
BSR56_RS06585	COG1643	Atp-dependent helicase
BSR56_RS06600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSR56_RS06625	COG2951	lytic endotransglycosylase activity
BSR56_RS06630	COG0772	Belongs to the SEDS family
BSR56_RS06645	COG0842	Transport permease protein
BSR56_RS06650	COG1131	(ABC) transporter
BSR56_RS06655	COG3676	manually curated
BSR56_RS06710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSR56_RS06720	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSR56_RS06740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BSR56_RS06765	COG0729	surface antigen
BSR56_RS06805	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR56_RS06810	COG4605	iron ion homeostasis
BSR56_RS06815	COG4604	ABC transporter, ATP-binding protein
BSR56_RS06820	COG4607	ABC-type enterochelin transport system periplasmic component
BSR56_RS06825	COG2814	Major facilitator Superfamily
BSR56_RS06835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSR56_RS06840	COG0583	DNA-binding transcription factor activity
BSR56_RS06870	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS06885	COG1720	tRNA m6t6A37 methyltransferase activity
BSR56_RS06890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSR56_RS06905	COG0642	Histidine kinase
BSR56_RS06915	COG0494	nUDIX hydrolase
BSR56_RS06925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSR56_RS06935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSR56_RS06940	COG3139	Protein of unknown function (DUF1315)
BSR56_RS06965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSR56_RS06970	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS06990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSR56_RS07030	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS07050	COG3539	Fimbrial protein
BSR56_RS07075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSR56_RS07075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSR56_RS07095	COG1278	Cold shock
BSR56_RS07100	COG1278	Cold shock
BSR56_RS07110	COG3042	response to heat
BSR56_RS07160	COG0436	Aminotransferase
BSR56_RS07165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSR56_RS07170	COG0386	Belongs to the glutathione peroxidase family
BSR56_RS07180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR56_RS07185	COG1522	sequence-specific DNA binding
BSR56_RS07195	COG0436	Aminotransferase
BSR56_RS07220	COG1253	flavin adenine dinucleotide binding
BSR56_RS07225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSR56_RS07235	COG0012	GTP binding
BSR56_RS07240	COG2011	ABC-type metal ion transport system permease component
BSR56_RS07245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BSR56_RS07250	COG1464	Belongs to the NlpA lipoprotein family
BSR56_RS07280	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSR56_RS07290	COG3550	peptidyl-serine autophosphorylation
BSR56_RS07330	COG2363	Small membrane protein
BSR56_RS07350	COG0513	Belongs to the DEAD box helicase family
BSR56_RS07360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSR56_RS07375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSR56_RS07385	COG1192	Involved in chromosome partitioning
BSR56_RS07390	COG1475	DNA binding
BSR56_RS07395	COG0811	peptide transport
BSR56_RS07405	COG1132	(ABC) transporter
BSR56_RS07410	COG1663	tetraacyldisaccharide 4'-kinase activity
BSR56_RS07440	COG0084	hydrolase, TatD family'
BSR56_RS07505	COG0776	regulation of translation
BSR56_RS07520	COG2431	L-lysine efflux transmembrane transporter activity
BSR56_RS07525	COG1309	transcriptional regulator
BSR56_RS07530	COG2814	Major facilitator Superfamily
BSR56_RS07545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSR56_RS07550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSR56_RS07590	COG0024	Methionine aminopeptidase
BSR56_RS07595	COG0583	DNA-binding transcription factor activity
BSR56_RS07605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSR56_RS07610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSR56_RS07615	COG0517	IMP dehydrogenase activity
BSR56_RS07615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSR56_RS07640	COG0552	protein localization to endoplasmic reticulum
BSR56_RS07665	COG4890	Cyd operon protein YbgT
BSR56_RS07670	COG1294	oxidase, subunit
BSR56_RS07690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSR56_RS07710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSR56_RS07715	COG0569	domain protein
BSR56_RS07720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSR56_RS07725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSR56_RS07730	COG1451	nucleotide metabolic process
BSR56_RS07760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSR56_RS07770	COG0542	response to heat
BSR56_RS07780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BSR56_RS07785	COG2267	carboxylic ester hydrolase activity
BSR56_RS07795	COG1902	pentaerythritol trinitrate reductase activity
BSR56_RS07795	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSR56_RS07830	COG0148	phosphopyruvate hydratase activity
BSR56_RS07835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BSR56_RS07890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSR56_RS07900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSR56_RS07915	COG1802	Transcriptional regulator
BSR56_RS07930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSR56_RS07960	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS07985	COG1944	ATP diphosphatase activity
BSR56_RS08010	COG0583	DNA-binding transcription factor activity
BSR56_RS08020	COG4774	siderophore transport
BSR56_RS08050	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSR56_RS08060	COG3706	GGDEF domain
BSR56_RS08080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSR56_RS08100	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSR56_RS08145	COG0537	adenosine 5'-monophosphoramidase activity
BSR56_RS08175	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSR56_RS08195	COG0730	response to heat
BSR56_RS08200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BSR56_RS08210	COG4771	TonB-dependent receptor
BSR56_RS08230	COG0406	alpha-ribazole phosphatase activity
BSR56_RS08250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSR56_RS08270	COG2814	Major facilitator Superfamily
BSR56_RS08315	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS08320	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS08325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSR56_RS08330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSR56_RS08335	COG2207	Transcriptional regulator
BSR56_RS08340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSR56_RS08380	COG0575	Belongs to the CDS family
BSR56_RS08385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSR56_RS08395	COG0528	UMP kinase activity
BSR56_RS08405	COG3852	Histidine kinase
BSR56_RS08410	COG2204	response regulator
BSR56_RS08415	COG1309	transcriptional regulator
BSR56_RS08455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSR56_RS08460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BSR56_RS08480	COG0697	spore germination
BSR56_RS08485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR56_RS08495	COG0303	'Molybdopterin
BSR56_RS08500	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSR56_RS08500	COG0315	cyclic pyranopterin monophosphate synthase activity
BSR56_RS08515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSR56_RS08520	COG0243	molybdopterin cofactor binding
BSR56_RS08535	COG0243	molybdopterin cofactor binding
BSR56_RS08540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR56_RS08545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR56_RS08545	COG2146	nitrite reductase [NAD(P)H] activity
BSR56_RS08550	COG2223	nitrite transmembrane transporter activity
BSR56_RS08560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSR56_RS08560	COG1116	anion transmembrane transporter activity
BSR56_RS08575	COG0439	Biotin carboxylase
BSR56_RS08590	COG2814	Major facilitator Superfamily
BSR56_RS08605	COG0069	glutamate synthase activity
BSR56_RS08625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSR56_RS08630	COG2963	transposase activity
BSR56_RS08640	COG4372	Transposase
BSR56_RS08645	COG3038	cytochrome b561
BSR56_RS08655	COG1454	alcohol dehydrogenase
BSR56_RS08660	COG0824	Thioesterase
BSR56_RS08670	COG2850	peptidyl-arginine hydroxylation
BSR56_RS08695	COG0640	Transcriptional regulator
BSR56_RS08715	COG3122	Protein conserved in bacteria
BSR56_RS08720	COG0668	transmembrane transport
BSR56_RS08735	COG1132	(ABC) transporter
BSR56_RS08755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR56_RS08765	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSR56_RS08765	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSR56_RS08765	COG0506	proline dehydrogenase activity
BSR56_RS08775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSR56_RS08785	COG3698	Phosphodiester glycosidase
BSR56_RS08805	COG3153	acetyltransferase
BSR56_RS08810	COG2353	YceI-like domain
BSR56_RS08825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BSR56_RS08830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSR56_RS08845	COG3634	alkyl hydroperoxide reductase activity
BSR56_RS08885	COG1286	toxin biosynthetic process
BSR56_RS08940	COG0424	maF-like protein
BSR56_RS08945	COG0583	DNA-binding transcription factor activity
BSR56_RS08995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSR56_RS09010	COG0183	Belongs to the thiolase family
BSR56_RS09025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BSR56_RS09030	COG0702	epimerase
BSR56_RS09035	COG0268	Binds directly to 16S ribosomal RNA
BSR56_RS09055	COG1218	3'(2'),5'-bisphosphate nucleotidase
BSR56_RS09060	COG1011	Hydrolase
BSR56_RS09065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BSR56_RS09075	COG2137	regulation of response to DNA damage stimulus
BSR56_RS09095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSR56_RS09100	COG0776	regulation of translation
BSR56_RS09125	COG0822	iron-sulfur transferase activity
BSR56_RS09130	COG0316	Belongs to the HesB IscA family
BSR56_RS09160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSR56_RS09185	COG0583	DNA-binding transcription factor activity
BSR56_RS09190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSR56_RS09200	COG3135	benzoate transporter
BSR56_RS09205	COG0475	glutathione-regulated potassium exporter activity
BSR56_RS09205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSR56_RS09215	COG1714	RDD family
BSR56_RS09225	COG1760	l-serine dehydratase
BSR56_RS09230	COG0308	aminopeptidase N
BSR56_RS09260	COG4133	protoheme IX ABC transporter activity
BSR56_RS09310	COG1765	OsmC-like protein
BSR56_RS09320	COG0501	Belongs to the peptidase M48B family
BSR56_RS09340	COG0439	Biotin carboxylase
BSR56_RS09345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BSR56_RS09350	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSR56_RS09355	COG1560	Kdo2-lipid A biosynthetic process
BSR56_RS09360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BSR56_RS09365	COG2072	flavoprotein involved in K transport
BSR56_RS09385	COG1309	transcriptional regulator
BSR56_RS09405	COG0642	Histidine kinase
BSR56_RS09410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSR56_RS09420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSR56_RS09440	COG3040	lipid binding
BSR56_RS09450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSR56_RS09455	COG0243	molybdopterin cofactor binding
BSR56_RS09465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR56_RS09470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSR56_RS09475	COG0010	Belongs to the arginase family
BSR56_RS09500	COG2188	Transcriptional regulator
BSR56_RS09510	COG0583	DNA-binding transcription factor activity
BSR56_RS09550	COG4266	Belongs to the allantoicase family
BSR56_RS09560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSR56_RS09580	COG2233	PERMEase
BSR56_RS09585	COG2351	hydroxyisourate hydrolase activity
BSR56_RS09595	COG4993	Dehydrogenase
BSR56_RS09600	COG3659	wide pore channel activity
BSR56_RS09605	COG3420	alginic acid biosynthetic process
BSR56_RS09610	COG0710	3-dehydroquinate dehydratase activity
BSR56_RS09615	COG3485	protocatechuate 3,4-dioxygenase
BSR56_RS09620	COG3485	protocatechuate 3,4-dioxygenase
BSR56_RS09625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSR56_RS09635	COG0596	Alpha beta hydrolase
BSR56_RS09640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSR56_RS09645	COG0183	Belongs to the thiolase family
BSR56_RS09650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSR56_RS09655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BSR56_RS09660	COG1414	Transcriptional regulator
BSR56_RS09665	COG0523	cobalamin synthesis protein
BSR56_RS09680	COG1469	GTP cyclohydrolase I activity
BSR56_RS09685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSR56_RS09690	COG4451	ribulose bisphosphate carboxylase, small
BSR56_RS09690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BSR56_RS09725	COG1902	pentaerythritol trinitrate reductase activity
BSR56_RS09725	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSR56_RS09740	COG1741	Belongs to the pirin family
BSR56_RS09785	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS09830	COG0714	Associated with various cellular activities
BSR56_RS09835	COG2879	small protein
BSR56_RS09840	COG1966	Carbon starvation protein
BSR56_RS09845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSR56_RS09865	COG0254	rRNA binding
BSR56_RS09885	COG1067	ATP-dependent peptidase activity
BSR56_RS09890	COG0583	DNA-binding transcription factor activity
BSR56_RS09900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSR56_RS09925	COG3188	usher protein
BSR56_RS09980	COG1686	Belongs to the peptidase S11 family
BSR56_RS09985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BSR56_RS09995	COG0482	sulfurtransferase activity
BSR56_RS10095	COG1610	YqeY-like protein
BSR56_RS10155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSR56_RS10190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSR56_RS10200	COG4122	O-methyltransferase activity
BSR56_RS10235	COG1137	ATPase activity
BSR56_RS10240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BSR56_RS10250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BSR56_RS10255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSR56_RS10255	COG0517	IMP dehydrogenase activity
BSR56_RS10270	COG3015	lipoprotein NlpE involved in copper resistance
BSR56_RS10285	COG1253	flavin adenine dinucleotide binding
BSR56_RS10290	COG0222	ribosome binding
BSR56_RS10305	COG0175	sulfate reduction
BSR56_RS10315	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSR56_RS10325	COG1773	rubredoxin
BSR56_RS10330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR56_RS10335	COG0596	Alpha beta hydrolase
BSR56_RS10340	COG0583	DNA-binding transcription factor activity
BSR56_RS10350	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS10370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSR56_RS10375	COG1840	ABC-type Fe3 transport system, periplasmic component
BSR56_RS10420	COG0556	nucleotide-excision repair
BSR56_RS10440	COG0436	Aminotransferase
BSR56_RS10465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSR56_RS10480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSR56_RS10485	COG0571	ribonuclease III activity
BSR56_RS10500	COG0481	GTPase activity
BSR56_RS10510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSR56_RS10560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSR56_RS10565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSR56_RS10570	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSR56_RS10580	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BSR56_RS10585	COG4208	sulfate ABC transporter
BSR56_RS10590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSR56_RS10595	COG0583	DNA-binding transcription factor activity
BSR56_RS10610	COG0602	queuosine metabolic process
BSR56_RS10615	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSR56_RS10630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSR56_RS10650	COG1942	4-Oxalocrotonate Tautomerase
BSR56_RS10655	COG0583	DNA-binding transcription factor activity
BSR56_RS10660	COG1051	belongs to the nudix hydrolase family
BSR56_RS10660	COG1056	cytidyltransferase-related domain
BSR56_RS10665	COG1024	Enoyl-CoA hydratase
BSR56_RS10675	COG3293	Transposase
BSR56_RS10685	COG1105	Belongs to the carbohydrate kinase PfkB family
BSR56_RS10690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSR56_RS10690	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BSR56_RS10690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSR56_RS10695	COG0778	Nitroreductase
BSR56_RS10700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSR56_RS10700	COG3323	Protein of unknown function (DUF1653)
BSR56_RS10710	COG0047	phosphoribosylformylglycinamidine synthase activity
BSR56_RS10710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSR56_RS10740	COG0824	Thioesterase
BSR56_RS10760	COG0823	Involved in the tonB-independent uptake of proteins
BSR56_RS10780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSR56_RS10830	COG0628	permease
BSR56_RS10840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSR56_RS10850	COG0616	signal peptide processing
BSR56_RS10850	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSR56_RS10875	COG1136	(ABC) transporter
BSR56_RS10880	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSR56_RS10895	COG1671	Belongs to the UPF0178 family
BSR56_RS10915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR56_RS10955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSR56_RS10960	COG1280	lysine exporter protein (LysE YggA)
BSR56_RS10970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSR56_RS10975	COG0019	diaminopimelate decarboxylase activity
BSR56_RS10985	COG1115	amino acid carrier protein
BSR56_RS11000	COG0306	phosphate transporter
BSR56_RS11030	COG0242	peptide deformylase activity
BSR56_RS11045	COG0589	response to stress
BSR56_RS11075	COG2175	clavaminate synthase activity
BSR56_RS11080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSR56_RS11085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BSR56_RS11090	COG4521	taurine ABC transporter
BSR56_RS11105	COG4149	molybdate abc transporter
BSR56_RS11110	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSR56_RS11125	COG3293	Transposase
BSR56_RS11150	COG3293	Transposase
BSR56_RS11175	COG2885	chlorophyll binding
BSR56_RS11200	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS11205	COG0583	DNA-binding transcription factor activity
BSR56_RS11210	COG1301	dicarboxylic acid transport
BSR56_RS11225	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BSR56_RS11240	COG1196	nuclear chromosome segregation
BSR56_RS11240	COG0739	heme binding
BSR56_RS11240	COG0741	lytic transglycosylase activity
BSR56_RS11245	COG0501	Belongs to the peptidase M48B family
BSR56_RS11255	COG2239	Acts as a magnesium transporter
BSR56_RS11260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSR56_RS11265	COG2194	sulfuric ester hydrolase activity
BSR56_RS11270	COG0584	glycerophosphoryl diester phosphodiesterase
BSR56_RS11295	COG2304	oxidoreductase activity
BSR56_RS11310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSR56_RS11335	COG0505	Belongs to the CarA family
BSR56_RS11355	COG0110	maltose O-acetyltransferase activity
BSR56_RS11380	COG2321	neutral zinc metallopeptidase
BSR56_RS11385	COG2354	Protein conserved in bacteria
BSR56_RS11395	COG1585	Membrane protein implicated in regulation of membrane protease activity
BSR56_RS11400	COG2268	Band 7 protein
BSR56_RS11415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSR56_RS11435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSR56_RS11440	COG1053	succinate dehydrogenase
BSR56_RS11445	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BSR56_RS11450	COG2009	succinate dehydrogenase
BSR56_RS11465	COG1054	Belongs to the UPF0176 family
BSR56_RS11470	COG0586	Pfam SNARE associated Golgi protein
BSR56_RS11475	COG0500	methyltransferase
BSR56_RS11485	COG1280	lysine exporter protein (LysE YggA)
BSR56_RS11515	COG0321	lipoyl(octanoyl) transferase activity
BSR56_RS11530	COG0531	amino acid
BSR56_RS11540	COG1733	regulation of RNA biosynthetic process
BSR56_RS11550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSR56_RS11555	COG1648	precorrin-2 dehydrogenase activity
BSR56_RS11555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSR56_RS11570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSR56_RS11600	COG0671	phosphoesterase, PA-phosphatase related
BSR56_RS11605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR56_RS11615	COG1538	Outer membrane efflux protein
BSR56_RS11620	COG0393	Putative heavy-metal-binding
BSR56_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
BSR56_RS11650	COG0525	valine-tRNA ligase activity
BSR56_RS11670	COG0004	ammonium transporteR
BSR56_RS11685	COG0642	Histidine kinase
BSR56_RS11695	COG2194	sulfuric ester hydrolase activity
BSR56_RS11715	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSR56_RS11730	COG0142	geranyltranstransferase activity
BSR56_RS11735	COG2828	Protein conserved in bacteria
BSR56_RS11740	COG1113	amino acid transport
BSR56_RS11765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSR56_RS11775	COG0671	phosphoesterase, PA-phosphatase related
BSR56_RS11785	COG0745	RESPONSE REGULATOR receiver
BSR56_RS11790	COG2205	protein histidine kinase activity
BSR56_RS11795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BSR56_RS11800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BSR56_RS11805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BSR56_RS11820	COG0560	Phosphoserine phosphatase
BSR56_RS11830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR56_RS11840	COG1530	ribonuclease E activity
BSR56_RS11845	COG0424	maF-like protein
BSR56_RS11855	COG1792	Involved in formation and maintenance of cell shape
BSR56_RS11860	COG1077	Cell shape determining protein MreB Mrl
BSR56_RS11865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSR56_RS11875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSR56_RS11925	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BSR56_RS11930	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSR56_RS11935	COG1115	amino acid carrier protein
BSR56_RS11940	COG0786	glutamate:sodium symporter activity
BSR56_RS11955	COG2814	Major facilitator Superfamily
BSR56_RS11960	COG1289	transmembrane transporter activity
BSR56_RS11970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSR56_RS12015	COG1376	ErfK ybiS ycfS ynhG family protein
BSR56_RS12020	COG2832	Protein of unknown function (DUF454)
BSR56_RS12030	COG5510	response to toxic substance
BSR56_RS12045	COG2198	Histidine kinase
BSR56_RS12045	COG0643	Histidine kinase
BSR56_RS12045	COG2198	Histidine kinase
BSR56_RS12045	COG0643	Histidine kinase
BSR56_RS12050	COG0840	transmembrane signaling receptor activity
BSR56_RS12080	COG3422	double-strand break repair
BSR56_RS12085	COG2824	Alkylphosphonate utilization operon protein PhnA
BSR56_RS12095	COG0354	folic acid binding
BSR56_RS12105	COG4772	TonB-dependent receptor
BSR56_RS12130	COG1217	gtp-binding protein TYPA
BSR56_RS12135	COG2233	PERMEase
BSR56_RS12145	COG0833	amino acid
BSR56_RS12150	COG1690	Belongs to the RtcB family
BSR56_RS12155	COG2885	chlorophyll binding
BSR56_RS12155	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BSR56_RS12165	COG2885	chlorophyll binding
BSR56_RS12165	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BSR56_RS12175	COG0183	Belongs to the thiolase family
BSR56_RS12190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR56_RS12200	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS12215	COG0739	heme binding
BSR56_RS12245	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS12265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSR56_RS12280	COG1002	Type II restriction enzyme, methylase subunits
BSR56_RS12295	COG4584	PFAM Integrase catalytic
BSR56_RS12300	COG1484	DNA-dependent DNA replication
BSR56_RS12305	COG0739	heme binding
BSR56_RS12310	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS12335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSR56_RS12340	COG2207	Transcriptional regulator
BSR56_RS12350	COG0183	Belongs to the thiolase family
BSR56_RS12385	COG1272	protein, Hemolysin III
BSR56_RS12390	COG0477	Major facilitator Superfamily
BSR56_RS12410	COG0450	alkyl hydroperoxide reductase
BSR56_RS12425	COG0285	dihydrofolate synthase activity
BSR56_RS12515	COG4206	TonB-dependent receptor
BSR56_RS12520	COG2096	Adenosyltransferase
BSR56_RS12540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSR56_RS12555	COG0745	RESPONSE REGULATOR receiver
BSR56_RS12560	COG2205	protein histidine kinase activity
BSR56_RS12570	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS12575	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS12615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSR56_RS12630	COG3306	glycosyltransferase involved in LPS biosynthesis
BSR56_RS12680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSR56_RS12690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSR56_RS12695	COG5002	protein histidine kinase activity
BSR56_RS12730	COG1862	Preprotein translocase
BSR56_RS12740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSR56_RS12775	COG1426	Protein conserved in bacteria
BSR56_RS12795	COG2975	iron-sulfur cluster assembly
BSR56_RS12810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSR56_RS12815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSR56_RS12820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSR56_RS12835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSR56_RS12840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSR56_RS12845	COG0625	glutathione transferase activity
BSR56_RS12850	COG2969	positive regulation of protein catabolic process
BSR56_RS12905	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS12910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSR56_RS12920	COG4456	Virulence-associated protein
BSR56_RS12945	COG1309	transcriptional regulator
BSR56_RS12960	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS13000	COG1183	phosphatidylcholine synthase activity
BSR56_RS13005	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSR56_RS13035	COG1196	nuclear chromosome segregation
BSR56_RS13035	COG0739	heme binding
BSR56_RS13035	COG0741	lytic transglycosylase activity
BSR56_RS13045	COG1702	phosphate starvation-inducible protein PhoH
BSR56_RS13135	COG0788	formyltetrahydrofolate deformylase activity
BSR56_RS13160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSR56_RS13160	COG4651	solute:proton antiporter activity
BSR56_RS13180	COG0210	DNA helicase
BSR56_RS13205	COG1733	regulation of RNA biosynthetic process
BSR56_RS13215	COG2900	Belongs to the SlyX family
BSR56_RS13220	COG0488	(ABC) transporter
BSR56_RS13230	COG1560	Kdo2-lipid A biosynthetic process
BSR56_RS13280	COG0473	3-isopropylmalate dehydrogenase activity
BSR56_RS13315	COG0494	nUDIX hydrolase
BSR56_RS13335	COG3011	Protein conserved in bacteria
BSR56_RS13350	COG0625	glutathione transferase activity
BSR56_RS13365	COG0564	pseudouridine synthase activity
BSR56_RS13375	COG1530	ribonuclease E activity
BSR56_RS13380	COG0318	PFAM AMP-dependent synthetase and ligase
BSR56_RS13395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSR56_RS13405	COG0534	Mate efflux family protein
BSR56_RS13410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSR56_RS13430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSR56_RS13445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BSR56_RS13445	COG0493	'glutamate synthase
BSR56_RS13455	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSR56_RS13495	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS13515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR56_RS13530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSR56_RS13540	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BSR56_RS13540	COG0644	oxidoreductase
BSR56_RS13545	COG0425	Belongs to the sulfur carrier protein TusA family
BSR56_RS13550	COG4535	Mg2 and Co2 transporter CorC
BSR56_RS13555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSR56_RS13575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSR56_RS13585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSR56_RS13600	COG0789	Transcriptional regulator
BSR56_RS13605	COG0598	Magnesium transport protein CorA
BSR56_RS13610	COG1185	polyribonucleotide nucleotidyltransferase activity
BSR56_RS13615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSR56_RS13620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSR56_RS13625	COG3676	manually curated
BSR56_RS13630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSR56_RS13635	COG1074	ATP-dependent DNA helicase activity
BSR56_RS13640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BSR56_RS13665	COG2226	methyltransferase
BSR56_RS13680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSR56_RS13690	COG1116	anion transmembrane transporter activity
BSR56_RS13695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSR56_RS13705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSR56_RS13720	COG2111	Na H antiporter
BSR56_RS13720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSR56_RS13725	COG1006	Multisubunit Na H antiporter MnhC subunit
BSR56_RS13730	COG0651	ATP synthesis coupled electron transport
BSR56_RS13735	COG1863	multisubunit Na H antiporter MnhE subunit
BSR56_RS13740	COG2212	antiporter activity
BSR56_RS13745	COG1320	monovalent cation:proton antiporter activity
BSR56_RS13780	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS13815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSR56_RS13825	COG0195	Participates in both transcription termination and antitermination
BSR56_RS13875	COG0237	dephospho-CoA kinase activity
BSR56_RS13890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSR56_RS13900	COG0497	DNA recombination
BSR56_RS13910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSR56_RS13935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSR56_RS13985	COG0326	Molecular chaperone. Has ATPase activity
BSR56_RS13995	COG2056	Na+-H+ antiporter family
BSR56_RS14045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSR56_RS14055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSR56_RS14065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSR56_RS14095	COG0546	phosphoglycolate phosphatase activity
BSR56_RS14100	COG1716	ATPase activity
BSR56_RS14145	COG0181	hydroxymethylbilane synthase activity
BSR56_RS14155	COG3275	phosphorelay sensor kinase activity
BSR56_RS14180	COG0494	nUDIX hydrolase
BSR56_RS14190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSR56_RS14195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSR56_RS14200	COG0772	Belongs to the SEDS family
BSR56_RS14225	COG4974	Belongs to the 'phage' integrase family
BSR56_RS14230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSR56_RS14240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSR56_RS14245	COG1686	Belongs to the peptidase S11 family
BSR56_RS14250	COG2197	response regulator
BSR56_RS14265	COG0793	Belongs to the peptidase S41A family
BSR56_RS14270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BSR56_RS14275	COG0795	lipopolysaccharide-transporting ATPase activity
BSR56_RS14280	COG0795	lipopolysaccharide-transporting ATPase activity
BSR56_RS14320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSR56_RS14320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSR56_RS14325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSR56_RS14330	COG0004	ammonium transporteR
BSR56_RS14335	COG0347	Belongs to the P(II) protein family
BSR56_RS14425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR56_RS14430	COG1230	cation diffusion facilitator family transporter
BSR56_RS14440	COG0640	Transcriptional regulator
BSR56_RS14450	COG0789	Transcriptional regulator
BSR56_RS14480	COG2814	Major facilitator Superfamily
BSR56_RS14520	COG0633	Ferredoxin
BSR56_RS14565	COG0606	chelatase, subunit chli
BSR56_RS14585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSR56_RS14600	COG0318	PFAM AMP-dependent synthetase and ligase
BSR56_RS14610	COG2860	membrane
BSR56_RS14620	COG1253	flavin adenine dinucleotide binding
BSR56_RS14645	COG2814	Major facilitator Superfamily
BSR56_RS14655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSR56_RS14705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSR56_RS14715	COG1283	sodium-dependent phosphate transmembrane transporter activity
BSR56_RS14750	COG2826	transposase and inactivated derivatives, IS30 family
BSR56_RS14770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR56_RS14775	COG3162	membrane
BSR56_RS14780	COG2205	protein histidine kinase activity
BSR56_RS14805	COG1652	LysM domain
BSR56_RS14810	COG0758	DNA mediated transformation
BSR56_RS14825	COG1309	transcriptional regulator
BSR56_RS14830	COG2814	Major facilitator Superfamily
BSR56_RS14840	COG0386	Belongs to the glutathione peroxidase family
BSR56_RS14865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSR56_RS14875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSR56_RS14915	COG1121	(ABC) transporter
BSR56_RS14920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSR56_RS14925	COG1280	lysine exporter protein (LysE YggA)
BSR56_RS14930	COG2837	iron assimilation
BSR56_RS14965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSR56_RS14995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSR56_RS14995	COG0519	Catalyzes the synthesis of GMP from XMP
BSR56_RS15000	COG4399	Belongs to the UPF0754 family
BSR56_RS15010	COG2259	Doxx family
BSR56_RS15015	COG0586	Pfam SNARE associated Golgi protein
BSR56_RS15030	COG1192	Involved in chromosome partitioning
BSR56_RS15040	COG0271	Belongs to the BolA IbaG family
BSR56_RS15075	COG3756	Protein conserved in bacteria
BSR56_RS15120	COG0735	belongs to the Fur family
BSR56_RS15200	COG3550	peptidyl-serine autophosphorylation
BSR56_RS15205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSR56_RS15250	COG4372	Transposase
BSR56_RS15305	COG0477	Major facilitator Superfamily
BSR56_RS15310	COG1024	Enoyl-CoA hydratase
BSR56_RS15315	COG1024	Enoyl-CoA hydratase
BSR56_RS15320	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS15325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSR56_RS15345	COG1113	amino acid transport
BSR56_RS15350	COG0251	oxidation-reduction process
BSR56_RS15375	COG0456	acetyltransferase
BSR56_RS15385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSR56_RS15410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSR56_RS15425	COG1802	Transcriptional regulator
BSR56_RS15430	COG1448	Aminotransferase
BSR56_RS15435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSR56_RS15440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSR56_RS15455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSR56_RS15465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSR56_RS15475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSR56_RS15520	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BSR56_RS15570	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSR56_RS15620	COG0546	phosphoglycolate phosphatase activity
BSR56_RS15625	COG1028	Short-chain dehydrogenase reductase Sdr
BSR56_RS15635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSR56_RS15635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSR56_RS15640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSR56_RS15645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSR56_RS15650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSR56_RS15655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSR56_RS15660	COG1116	anion transmembrane transporter activity
BSR56_RS15665	COG1309	transcriptional regulator
BSR56_RS15690	COG0196	riboflavin kinase activity
BSR56_RS15695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSR56_RS15705	COG1047	Peptidyl-prolyl cis-trans
BSR56_RS15750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSR56_RS15755	COG0657	acetylesterase activity
BSR56_RS15765	COG3293	Transposase
BSR56_RS15780	COG0583	DNA-binding transcription factor activity
BSR56_RS15790	COG0443	Heat shock 70 kDa protein
BSR56_RS15795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSR56_RS15825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSR56_RS15845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSR56_RS15870	COG1960	acyl-CoA dehydrogenase activity
BSR56_RS15880	COG0861	Integral membrane protein TerC family
BSR56_RS15885	COG0402	S-adenosylhomocysteine deaminase activity
BSR56_RS15900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSR56_RS15910	COG0706	membrane insertase activity
BSR56_RS15950	COG2963	transposase activity
BSR56_RS15960	COG4372	Transposase
BSR56_RS16000	COG1192	Involved in chromosome partitioning
BSR56_RS16005	COG1475	DNA binding
BSR56_RS16025	COG1373	ATPase (AAA superfamily