locus-tag	class	description
DX910_RS00010	COG1454	alcohol dehydrogenase
DX910_RS00015	COG1228	amidohydrolase
DX910_RS00070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DX910_RS00080	COG2072	flavoprotein involved in K transport
DX910_RS00100	COG2814	Major facilitator Superfamily
DX910_RS00110	COG2050	protein possibly involved in aromatic compounds catabolism
DX910_RS00145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DX910_RS00150	COG0420	3'-5' exonuclease activity
DX910_RS00190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DX910_RS00195	COG2914	Belongs to the UPF0125 (RnfH) family
DX910_RS00210	COG0121	glutamine amidotransferase
DX910_RS00230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DX910_RS00235	COG0756	dUTP diphosphatase activity
DX910_RS00245	COG2885	chlorophyll binding
DX910_RS00250	COG0204	Acyl-transferase
DX910_RS00260	COG0850	regulation of cytokinetic process
DX910_RS00270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DX910_RS00280	COG1280	lysine exporter protein (LysE YggA)
DX910_RS00285	COG1674	ftsk spoiiie
DX910_RS00285	COG0531	amino acid
DX910_RS00290	COG0492	ferredoxin-NADP+ reductase activity
DX910_RS00295	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DX910_RS00305	COG0456	acetyltransferase
DX910_RS00320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DX910_RS00330	COG0049	tRNA binding
DX910_RS00350	COG1981	membrane
DX910_RS00365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DX910_RS00365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DX910_RS00390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DX910_RS00400	COG0582	viral genome integration into host DNA
DX910_RS00615	COG0305	Participates in initiation and elongation during chromosome replication
DX910_RS00630	COG2932	Transcriptional regulator
DX910_RS00725	COG1496	oxidoreductase activity
DX910_RS00730	COG0564	pseudouridine synthase activity
DX910_RS00755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DX910_RS00785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DX910_RS00820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DX910_RS00835	COG0352	thiamine-phosphate diphosphorylase activity
DX910_RS00835	COG0351	phosphomethylpyrimidine kinase
DX910_RS00835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DX910_RS00845	COG1652	LysM domain
DX910_RS00870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DX910_RS00875	COG1399	metal-binding, possibly nucleic acid-binding protein
DX910_RS00880	COG3101	peptidyl-lysine hydroxylation
DX910_RS00905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DX910_RS00925	COG0601	transmembrane transport
DX910_RS00935	COG0747	negative chemotaxis
DX910_RS00980	COG4106	trans-aconitate 2-methyltransferase activity
DX910_RS00995	COG0596	Alpha beta hydrolase
DX910_RS00995	COG2226	methyltransferase
DX910_RS00995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DX910_RS01000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DX910_RS01055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DX910_RS01115	COG2358	TRAP transporter, solute receptor (TAXI family
DX910_RS01130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DX910_RS01155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DX910_RS01155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DX910_RS01170	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DX910_RS01195	COG2081	HI0933 family
DX910_RS01200	COG0668	transmembrane transport
DX910_RS01220	COG0583	DNA-binding transcription factor activity
DX910_RS01240	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DX910_RS01260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DX910_RS01275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DX910_RS01285	COG0649	NAD binding
DX910_RS01285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DX910_RS01310	COG2205	protein histidine kinase activity
DX910_RS01315	COG0745	RESPONSE REGULATOR receiver
DX910_RS01330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DX910_RS01345	COG2826	transposase and inactivated derivatives, IS30 family
DX910_RS01405	COG2826	transposase and inactivated derivatives, IS30 family
DX910_RS01485	COG1131	(ABC) transporter
DX910_RS01490	COG1448	Aminotransferase
DX910_RS01495	COG1113	amino acid transport
DX910_RS01505	COG0625	glutathione transferase activity
DX910_RS01530	COG2814	Major facilitator Superfamily
DX910_RS01545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DX910_RS01570	COG1063	alcohol dehydrogenase
DX910_RS01615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DX910_RS01620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DX910_RS01625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DX910_RS01630	COG2076	Multidrug Resistance protein
DX910_RS01660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DX910_RS01685	COG1968	undecaprenyl-diphosphatase activity
DX910_RS01690	COG1214	PFAM Peptidase M22, glycoprotease
DX910_RS01700	COG0494	nUDIX hydrolase
DX910_RS01755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DX910_RS01765	COG1595	DNA-templated transcription, initiation
DX910_RS01770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DX910_RS01840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DX910_RS01850	COG1764	response to oxidative stress
DX910_RS01875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DX910_RS01875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DX910_RS01925	COG0072	phenylalanine-tRNA ligase activity
DX910_RS01960	COG1238	metal cluster binding
DX910_RS01975	COG0625	glutathione transferase activity
DX910_RS02000	COG3028	Belongs to the UPF0307 family
DX910_RS02025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DX910_RS02030	COG0617	tRNA 3'-terminal CCA addition
DX910_RS02035	COG1555	photosystem II stabilization
DX910_RS02040	COG3956	TIGRFAM MazG family protein
DX910_RS02055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DX910_RS02085	COG2084	Dehydrogenase
DX910_RS02090	COG3622	Belongs to the hyi family
DX910_RS02130	COG2814	Major facilitator Superfamily
DX910_RS02135	COG5285	phytanoyl-CoA dioxygenase
DX910_RS02140	COG1917	Cupin 2, conserved barrel domain protein
DX910_RS02150	COG0456	acetyltransferase
DX910_RS02160	COG0431	NADPH-dependent FMN reductase
DX910_RS02175	COG0640	Transcriptional regulator
DX910_RS02195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DX910_RS02205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DX910_RS02225	COG0084	hydrolase, TatD family'
DX910_RS02240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DX910_RS02330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DX910_RS02335	COG0440	acetolactate synthase activity
DX910_RS02340	COG0028	Belongs to the TPP enzyme family
DX910_RS02360	COG1466	dna polymerase III delta subunit
DX910_RS02365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DX910_RS02370	COG0577	efflux transmembrane transporter activity
DX910_RS02370	COG1136	(ABC) transporter
DX910_RS02375	COG1538	Outer membrane efflux protein
DX910_RS02410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DX910_RS02415	COG1162	GTPase activity
DX910_RS02425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DX910_RS02460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DX910_RS02470	COG3781	membrane
DX910_RS02505	COG1666	GTP binding
DX910_RS02520	COG1956	GAF domain-containing protein
DX910_RS02525	COG1607	acyl-coa hydrolase
DX910_RS02580	COG1183	phosphatidylcholine synthase activity
DX910_RS02585	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DX910_RS02625	COG1702	phosphate starvation-inducible protein PhoH
DX910_RS02665	COG3878	Protein conserved in bacteria
DX910_RS02710	COG0788	formyltetrahydrofolate deformylase activity
DX910_RS02735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DX910_RS02735	COG4651	solute:proton antiporter activity
DX910_RS02755	COG0210	DNA helicase
DX910_RS02785	COG2900	Belongs to the SlyX family
DX910_RS02790	COG0488	(ABC) transporter
DX910_RS02800	COG1560	Kdo2-lipid A biosynthetic process
DX910_RS02850	COG0473	3-isopropylmalate dehydrogenase activity
DX910_RS02885	COG0494	nUDIX hydrolase
DX910_RS02905	COG3011	Protein conserved in bacteria
DX910_RS02920	COG0625	glutathione transferase activity
DX910_RS02965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DX910_RS02980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DX910_RS03040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DX910_RS03080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DX910_RS03095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DX910_RS03105	COG0644	oxidoreductase
DX910_RS03105	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DX910_RS03115	COG1595	DNA-templated transcription, initiation
DX910_RS03140	COG0425	Belongs to the sulfur carrier protein TusA family
DX910_RS03145	COG4535	Mg2 and Co2 transporter CorC
DX910_RS03150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DX910_RS03180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DX910_RS03195	COG0789	Transcriptional regulator
DX910_RS03200	COG0598	Magnesium transport protein CorA
DX910_RS03205	COG1185	polyribonucleotide nucleotidyltransferase activity
DX910_RS03210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DX910_RS03215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DX910_RS03220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DX910_RS03225	COG1074	ATP-dependent DNA helicase activity
DX910_RS03255	COG2226	methyltransferase
DX910_RS03270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DX910_RS03280	COG1116	anion transmembrane transporter activity
DX910_RS03295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DX910_RS03315	COG1006	Multisubunit Na H antiporter MnhC subunit
DX910_RS03320	COG0651	ATP synthesis coupled electron transport
DX910_RS03325	COG1863	multisubunit Na H antiporter MnhE subunit
DX910_RS03330	COG2212	antiporter activity
DX910_RS03335	COG1320	monovalent cation:proton antiporter activity
DX910_RS03345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DX910_RS03355	COG0195	Participates in both transcription termination and antitermination
DX910_RS03405	COG0237	dephospho-CoA kinase activity
DX910_RS03420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DX910_RS03430	COG0497	DNA recombination
DX910_RS03440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DX910_RS03465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DX910_RS03520	COG1132	(ABC) transporter
DX910_RS03530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DX910_RS03545	COG0326	Molecular chaperone. Has ATPase activity
DX910_RS03605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DX910_RS03615	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DX910_RS03625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DX910_RS03655	COG0546	phosphoglycolate phosphatase activity
DX910_RS03660	COG1716	ATPase activity
DX910_RS03705	COG0181	hydroxymethylbilane synthase activity
DX910_RS03715	COG3275	phosphorelay sensor kinase activity
DX910_RS03745	COG0494	nUDIX hydrolase
DX910_RS03755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DX910_RS03760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DX910_RS03765	COG0772	Belongs to the SEDS family
DX910_RS03790	COG4974	Belongs to the 'phage' integrase family
DX910_RS03795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DX910_RS03805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DX910_RS03810	COG1686	Belongs to the peptidase S11 family
DX910_RS03815	COG2197	response regulator
DX910_RS03830	COG0793	Belongs to the peptidase S41A family
DX910_RS03835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DX910_RS03845	COG0795	lipopolysaccharide-transporting ATPase activity
DX910_RS03880	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DX910_RS03880	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DX910_RS03885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DX910_RS03895	COG0347	Belongs to the P(II) protein family
DX910_RS03940	COG0318	PFAM AMP-dependent synthetase and ligase
DX910_RS03950	COG2860	membrane
DX910_RS03960	COG1253	flavin adenine dinucleotide binding
DX910_RS03980	COG2814	Major facilitator Superfamily
DX910_RS03990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DX910_RS04015	COG2814	Major facilitator Superfamily
DX910_RS04025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DX910_RS04075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DX910_RS04080	COG3162	membrane
DX910_RS04085	COG2205	protein histidine kinase activity
DX910_RS04110	COG1652	LysM domain
DX910_RS04115	COG0758	DNA mediated transformation
DX910_RS04130	COG1309	transcriptional regulator
DX910_RS04135	COG2814	Major facilitator Superfamily
DX910_RS04145	COG0386	Belongs to the glutathione peroxidase family
DX910_RS04170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DX910_RS04180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DX910_RS04220	COG1121	(ABC) transporter
DX910_RS04230	COG1280	lysine exporter protein (LysE YggA)
DX910_RS04235	COG2837	iron assimilation
DX910_RS04270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DX910_RS04290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DX910_RS04295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DX910_RS04295	COG0519	Catalyzes the synthesis of GMP from XMP
DX910_RS04300	COG4399	Belongs to the UPF0754 family
DX910_RS04310	COG2259	Doxx family
DX910_RS04315	COG0586	Pfam SNARE associated Golgi protein
DX910_RS04330	COG1192	Involved in chromosome partitioning
DX910_RS04340	COG0271	Belongs to the BolA IbaG family
DX910_RS04370	COG0477	Major facilitator Superfamily
DX910_RS04380	COG1024	Enoyl-CoA hydratase
DX910_RS04385	COG1960	acyl-CoA dehydrogenase activity
DX910_RS04390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DX910_RS04410	COG1113	amino acid transport
DX910_RS04415	COG0251	oxidation-reduction process
DX910_RS04445	COG0456	acetyltransferase
DX910_RS04455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DX910_RS04485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DX910_RS04500	COG1802	Transcriptional regulator
DX910_RS04505	COG1448	Aminotransferase
DX910_RS04525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DX910_RS04535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DX910_RS04545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DX910_RS04570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DX910_RS04580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DX910_RS04615	COG3023	N-Acetylmuramoyl-L-alanine amidase
DX910_RS04665	COG0546	phosphoglycolate phosphatase activity
DX910_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
DX910_RS04680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DX910_RS04680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DX910_RS04685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DX910_RS04690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DX910_RS04695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DX910_RS04700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DX910_RS04705	COG1116	anion transmembrane transporter activity
DX910_RS04710	COG1309	transcriptional regulator
DX910_RS04725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DX910_RS04735	COG0196	riboflavin kinase activity
DX910_RS04740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DX910_RS04750	COG1047	Peptidyl-prolyl cis-trans
DX910_RS04790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DX910_RS04795	COG0657	acetylesterase activity
DX910_RS04815	COG0583	DNA-binding transcription factor activity
DX910_RS04825	COG0443	Heat shock 70 kDa protein
DX910_RS04830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DX910_RS04855	COG2951	lytic endotransglycosylase activity
DX910_RS04860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DX910_RS04880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DX910_RS04900	COG1960	acyl-CoA dehydrogenase activity
DX910_RS04910	COG0861	Integral membrane protein TerC family
DX910_RS04920	COG0402	S-adenosylhomocysteine deaminase activity
DX910_RS04935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DX910_RS04945	COG0706	membrane insertase activity
DX910_RS04970	COG0592	DNA-directed DNA polymerase activity
DX910_RS04980	COG0187	DNA topoisomerase II activity
DX910_RS04985	COG0586	Pfam SNARE associated Golgi protein
DX910_RS04990	COG0488	(ABC) transporter
DX910_RS05020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DX910_RS05060	COG3273	potassium ion transport
DX910_RS05060	COG0471	metal ion transport
DX910_RS05070	COG1012	belongs to the aldehyde dehydrogenase family
DX910_RS05075	COG3738	Protein conserved in bacteria
DX910_RS05085	COG0733	neurotransmitter:sodium symporter activity
DX910_RS05125	COG0583	DNA-binding transcription factor activity
DX910_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
DX910_RS05135	COG2233	PERMEase
DX910_RS05150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DX910_RS05165	COG0484	heat shock protein binding
DX910_RS05180	COG2814	Major facilitator Superfamily
DX910_RS05185	COG0656	L-ascorbic acid biosynthetic process
DX910_RS05190	COG0583	DNA-binding transcription factor activity
DX910_RS05205	COG1064	alcohol dehydrogenase
DX910_RS05210	COG2818	Glycosylase
DX910_RS05225	COG1194	a g-specific adenine glycosylase
DX910_RS05235	COG5487	UPF0391 membrane protein
DX910_RS05240	COG2983	Belongs to the UPF0260 family
DX910_RS05270	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DX910_RS05280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DX910_RS05285	COG1335	isochorismatase
DX910_RS05325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DX910_RS05335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DX910_RS05340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DX910_RS05345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DX910_RS05365	COG0560	Phosphoserine phosphatase
DX910_RS05365	COG3830	Belongs to the UPF0237 family
DX910_RS05405	COG1278	Cold shock
DX910_RS05410	COG0583	DNA-binding transcription factor activity
DX910_RS05440	COG0534	Mate efflux family protein
DX910_RS05445	COG0436	Aminotransferase
DX910_RS05455	COG2733	membrane
DX910_RS05470	COG2918	glutathione biosynthetic process
DX910_RS05485	COG3150	esterase
DX910_RS05525	COG1247	-acetyltransferase
DX910_RS05555	COG0625	glutathione transferase activity
DX910_RS05575	COG1393	Belongs to the ArsC family
DX910_RS05580	COG0708	Exodeoxyribonuclease III
DX910_RS05630	COG0386	Belongs to the glutathione peroxidase family
DX910_RS05635	COG0189	ligase activity
DX910_RS05655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DX910_RS05690	COG0508	dehydrogenase complex catalyzes the overall conversion of
DX910_RS05705	COG2119	membrane
DX910_RS05710	COG4774	siderophore transport
DX910_RS05715	COG0426	domain, Protein
DX910_RS05715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DX910_RS05740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DX910_RS05765	COG1902	pentaerythritol trinitrate reductase activity
DX910_RS05780	COG0668	transmembrane transport
DX910_RS05785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DX910_RS05845	COG0351	phosphomethylpyrimidine kinase
DX910_RS05845	COG0352	thiamine-phosphate diphosphorylase activity
DX910_RS05845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DX910_RS05855	COG2814	Major facilitator Superfamily
DX910_RS05880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DX910_RS05885	COG1012	belongs to the aldehyde dehydrogenase family
DX910_RS05895	COG1335	isochorismatase
DX910_RS05905	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DX910_RS05950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DX910_RS05970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DX910_RS05995	COG0659	secondary active sulfate transmembrane transporter activity
DX910_RS06015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DX910_RS06050	COG0427	acetyl-CoA hydrolase
DX910_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
DX910_RS06090	COG0583	DNA-binding transcription factor activity
DX910_RS06100	COG0789	Transcriptional regulator
DX910_RS06105	COG3320	Male sterility
DX910_RS06105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DX910_RS06110	COG4221	oxidoreductase activity
DX910_RS06115	COG2873	o-acetylhomoserine
DX910_RS06120	COG0488	(ABC) transporter
DX910_RS06190	COG0833	amino acid
DX910_RS06215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DX910_RS06235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DX910_RS06240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DX910_RS06245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DX910_RS06250	COG2226	methyltransferase
DX910_RS06300	COG0067	glutamate synthase
DX910_RS06300	COG0069	glutamate synthase activity
DX910_RS06300	COG0070	glutamate synthase
DX910_RS06305	COG0493	'glutamate synthase
DX910_RS06315	COG1704	LemA family
DX910_RS06320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DX910_RS06350	COG3307	-O-antigen
DX910_RS06370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DX910_RS06380	COG0194	GDP metabolic process
DX910_RS06385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DX910_RS06390	COG4969	Belongs to the N-Me-Phe pilin family
DX910_RS06455	COG0228	four-way junction DNA binding
DX910_RS06460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DX910_RS06470	COG0335	large ribosomal subunit rRNA binding
DX910_RS06480	COG5380	lipid catabolic process
DX910_RS06485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DX910_RS06510	COG1196	nuclear chromosome segregation
DX910_RS06510	COG0739	heme binding
DX910_RS06510	COG0741	lytic transglycosylase activity
DX910_RS06515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DX910_RS06520	COG0277	FAD linked oxidase domain protein
DX910_RS06535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DX910_RS06540	COG2249	NAD(P)H dehydrogenase (quinone) activity
DX910_RS06555	COG1289	transmembrane transporter activity
DX910_RS06565	COG1192	Involved in chromosome partitioning
DX910_RS06575	COG2226	methyltransferase
DX910_RS06610	COG1404	Belongs to the peptidase S8 family
DX910_RS06670	COG0471	metal ion transport
DX910_RS06680	COG1983	PspC domain protein
DX910_RS06690	COG1960	acyl-CoA dehydrogenase activity
DX910_RS06705	COG0406	alpha-ribazole phosphatase activity
DX910_RS06745	COG1127	ABC transporter
DX910_RS06750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DX910_RS06755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DX910_RS06760	COG2854	intermembrane phospholipid transfer
DX910_RS06775	COG0598	Magnesium transport protein CorA
DX910_RS06790	COG1040	competence protein
DX910_RS06810	COG2937	Belongs to the GPAT DAPAT family
DX910_RS06815	COG1946	Acyl-CoA thioesterase
DX910_RS06820	COG1301	dicarboxylic acid transport
DX910_RS06840	COG1959	2 iron, 2 sulfur cluster binding
DX910_RS06850	COG0433	COG0433 Predicted ATPase
DX910_RS06870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DX910_RS06890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DX910_RS07020	COG1960	acyl-CoA dehydrogenase activity
DX910_RS07025	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DX910_RS07050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DX910_RS07075	COG0557	exoribonuclease II activity
DX910_RS07155	COG0179	Fumarylacetoacetate (FAA) hydrolase
DX910_RS07165	COG2207	Transcriptional regulator
DX910_RS07175	COG1295	ribonuclease BN
DX910_RS07205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DX910_RS07230	COG2813	Specifically methylates the guanine in position
DX910_RS07230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DX910_RS07240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DX910_RS07250	COG4771	TonB-dependent receptor
DX910_RS07260	COG0740	serine-type endopeptidase activity
DX910_RS07280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DX910_RS07280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DX910_RS07305	COG0857	belongs to the CobB CobQ family
DX910_RS07305	COG0280	phosphate acetyltransferase
DX910_RS07310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DX910_RS07320	COG2267	carboxylic ester hydrolase activity
DX910_RS07335	COG0793	Belongs to the peptidase S41A family
DX910_RS07355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DX910_RS07365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DX910_RS07380	COG2199	diguanylate cyclase activity
DX910_RS07415	COG0628	permease
DX910_RS07420	COG1960	acyl-CoA dehydrogenase activity
DX910_RS07435	COG1309	transcriptional regulator
DX910_RS07455	COG1960	acyl-CoA dehydrogenase activity
DX910_RS07510	COG2969	positive regulation of protein catabolic process
DX910_RS07520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DX910_RS07525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DX910_RS07535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DX910_RS07540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DX910_RS07545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DX910_RS07560	COG2975	iron-sulfur cluster assembly
DX910_RS07580	COG1426	Protein conserved in bacteria
DX910_RS07615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DX910_RS07625	COG1862	Preprotein translocase
DX910_RS07665	COG5002	protein histidine kinase activity
DX910_RS07680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DX910_RS07740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DX910_RS07780	COG1960	acyl-CoA dehydrogenase activity
DX910_RS07785	COG1960	acyl-CoA dehydrogenase activity
DX910_RS07795	COG2205	protein histidine kinase activity
DX910_RS07800	COG0745	RESPONSE REGULATOR receiver
DX910_RS07815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DX910_RS07835	COG2096	Adenosyltransferase
DX910_RS07840	COG4206	TonB-dependent receptor
DX910_RS07890	COG0285	dihydrofolate synthase activity
DX910_RS07905	COG0450	alkyl hydroperoxide reductase
DX910_RS07925	COG0477	Major facilitator Superfamily
DX910_RS07930	COG1272	protein, Hemolysin III
DX910_RS07965	COG0183	Belongs to the thiolase family
DX910_RS07980	COG2207	Transcriptional regulator
DX910_RS07985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DX910_RS08035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DX910_RS08050	COG0183	Belongs to the thiolase family
DX910_RS08060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DX910_RS08060	COG2885	chlorophyll binding
DX910_RS08065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DX910_RS08065	COG2885	chlorophyll binding
DX910_RS08070	COG1690	Belongs to the RtcB family
DX910_RS08075	COG0833	amino acid
DX910_RS08090	COG1217	gtp-binding protein TYPA
DX910_RS08095	COG1970	mechanosensitive ion channel activity
DX910_RS08120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DX910_RS08150	COG0354	folic acid binding
DX910_RS08160	COG2824	Alkylphosphonate utilization operon protein PhnA
DX910_RS08165	COG3422	double-strand break repair
DX910_RS08195	COG0840	transmembrane signaling receptor activity
DX910_RS08215	COG5510	response to toxic substance
DX910_RS08225	COG2832	Protein of unknown function (DUF454)
DX910_RS08230	COG1376	ErfK ybiS ycfS ynhG family protein
DX910_RS08275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DX910_RS08285	COG2985	domain, Protein
DX910_RS08295	COG1289	transmembrane transporter activity
DX910_RS08300	COG2814	Major facilitator Superfamily
DX910_RS08315	COG0786	glutamate:sodium symporter activity
DX910_RS08320	COG1115	amino acid carrier protein
DX910_RS08325	COG1752	Esterase of the alpha-beta hydrolase superfamily
DX910_RS08365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DX910_RS08370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DX910_RS08380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DX910_RS08385	COG1077	Cell shape determining protein MreB Mrl
DX910_RS08390	COG1792	Involved in formation and maintenance of cell shape
DX910_RS08400	COG0424	maF-like protein
DX910_RS08405	COG1530	ribonuclease E activity
DX910_RS08415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DX910_RS08425	COG0560	Phosphoserine phosphatase
DX910_RS08440	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DX910_RS08445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DX910_RS08450	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DX910_RS08460	COG0745	RESPONSE REGULATOR receiver
DX910_RS08470	COG0671	phosphoesterase, PA-phosphatase related
DX910_RS08480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DX910_RS08520	COG1113	amino acid transport
DX910_RS08530	COG0142	geranyltranstransferase activity
DX910_RS08545	COG1752	Esterase of the alpha-beta hydrolase superfamily
DX910_RS08565	COG2194	sulfuric ester hydrolase activity
DX910_RS08570	COG0745	RESPONSE REGULATOR receiver
DX910_RS08585	COG1126	abc transporter atp-binding protein
DX910_RS08590	COG0765	amino acid transport
DX910_RS08595	COG0765	amino acid transport
DX910_RS08605	COG0004	ammonium transporteR
DX910_RS08630	COG0525	valine-tRNA ligase activity
DX910_RS08660	COG0393	Putative heavy-metal-binding
DX910_RS08665	COG1538	Outer membrane efflux protein
DX910_RS08675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DX910_RS08680	COG0671	phosphoesterase, PA-phosphatase related
DX910_RS08710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DX910_RS08725	COG1648	precorrin-2 dehydrogenase activity
DX910_RS08725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DX910_RS08730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DX910_RS08740	COG1733	regulation of RNA biosynthetic process
DX910_RS08750	COG0531	amino acid
DX910_RS08765	COG0321	lipoyl(octanoyl) transferase activity
DX910_RS08795	COG1280	lysine exporter protein (LysE YggA)
DX910_RS08805	COG0500	methyltransferase
DX910_RS08810	COG0586	Pfam SNARE associated Golgi protein
DX910_RS08815	COG1054	Belongs to the UPF0176 family
DX910_RS08830	COG2009	succinate dehydrogenase
DX910_RS08835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DX910_RS08840	COG1053	succinate dehydrogenase
DX910_RS08845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DX910_RS08865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DX910_RS08890	COG2268	Band 7 protein
DX910_RS08905	COG2354	Protein conserved in bacteria
DX910_RS08985	COG0110	maltose O-acetyltransferase activity
DX910_RS09005	COG0505	Belongs to the CarA family
DX910_RS09030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DX910_RS09070	COG0584	glycerophosphoryl diester phosphodiesterase
DX910_RS09075	COG2194	sulfuric ester hydrolase activity
DX910_RS09085	COG2239	Acts as a magnesium transporter
DX910_RS09095	COG0501	Belongs to the peptidase M48B family
DX910_RS09100	COG0739	heme binding
DX910_RS09100	COG0741	lytic transglycosylase activity
DX910_RS09100	COG1196	nuclear chromosome segregation
DX910_RS09115	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DX910_RS09120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DX910_RS09130	COG1301	dicarboxylic acid transport
DX910_RS09135	COG0583	DNA-binding transcription factor activity
DX910_RS09235	COG0725	ABC transporter, periplasmic molybdate-binding protein
DX910_RS09240	COG4149	molybdate abc transporter
DX910_RS09245	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DX910_RS09255	COG1230	cation diffusion facilitator family transporter
DX910_RS09270	COG4521	taurine ABC transporter
DX910_RS09275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DX910_RS09280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DX910_RS09285	COG2175	clavaminate synthase activity
DX910_RS09310	COG0589	response to stress
DX910_RS09325	COG0242	peptide deformylase activity
DX910_RS09340	COG2852	Protein conserved in bacteria
DX910_RS09360	COG0306	phosphate transporter
DX910_RS09385	COG0019	diaminopimelate decarboxylase activity
DX910_RS09390	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DX910_RS09400	COG1280	lysine exporter protein (LysE YggA)
DX910_RS09405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DX910_RS09475	COG1671	Belongs to the UPF0178 family
DX910_RS09495	COG1136	(ABC) transporter
DX910_RS09510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DX910_RS09510	COG0616	signal peptide processing
DX910_RS09520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DX910_RS09530	COG0628	permease
DX910_RS09590	COG0823	Involved in the tonB-independent uptake of proteins
DX910_RS09610	COG0824	Thioesterase
DX910_RS09620	COG2255	four-way junction helicase activity
DX910_RS09655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DX910_RS09655	COG3323	Protein of unknown function (DUF1653)
DX910_RS09660	COG0778	Nitroreductase
DX910_RS09665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DX910_RS09665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DX910_RS09665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DX910_RS09670	COG1105	Belongs to the carbohydrate kinase PfkB family
DX910_RS09680	COG1024	Enoyl-CoA hydratase
DX910_RS09685	COG1051	belongs to the nudix hydrolase family
DX910_RS09685	COG1056	cytidyltransferase-related domain
DX910_RS09690	COG0583	DNA-binding transcription factor activity
DX910_RS09695	COG1942	4-Oxalocrotonate Tautomerase
DX910_RS09715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DX910_RS09730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DX910_RS09735	COG0602	queuosine metabolic process
DX910_RS09750	COG0583	DNA-binding transcription factor activity
DX910_RS09765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DX910_RS09780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DX910_RS09785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DX910_RS09805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DX910_RS09815	COG0481	GTPase activity
DX910_RS09830	COG0571	ribonuclease III activity
DX910_RS09835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DX910_RS09850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DX910_RS09875	COG0436	Aminotransferase
DX910_RS09895	COG0556	nucleotide-excision repair
DX910_RS09940	COG1840	ABC-type Fe3 transport system, periplasmic component
DX910_RS09945	COG3842	ATPase activity
DX910_RS09970	COG0596	Alpha beta hydrolase
DX910_RS09980	COG1773	rubredoxin
DX910_RS09990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DX910_RS10000	COG0175	sulfate reduction
DX910_RS10015	COG0222	ribosome binding
DX910_RS10020	COG1253	flavin adenine dinucleotide binding
DX910_RS10035	COG3015	lipoprotein NlpE involved in copper resistance
DX910_RS10050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DX910_RS10050	COG0517	IMP dehydrogenase activity
DX910_RS10055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DX910_RS10065	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DX910_RS10160	COG4122	O-methyltransferase activity
DX910_RS10170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DX910_RS10195	COG0583	DNA-binding transcription factor activity
DX910_RS10225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DX910_RS10255	COG4783	chaperone-mediated protein folding
DX910_RS10270	COG1610	YqeY-like protein
DX910_RS10345	COG1414	Transcriptional regulator
DX910_RS10365	COG1028	Short-chain dehydrogenase reductase Sdr
DX910_RS10375	COG0446	pyridine nucleotide-disulphide oxidoreductase
DX910_RS10380	COG2271	Major facilitator Superfamily
DX910_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
DX910_RS10410	COG0028	Belongs to the TPP enzyme family
DX910_RS10445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DX910_RS10450	COG1686	Belongs to the peptidase S11 family
DX910_RS10480	COG0583	DNA-binding transcription factor activity
DX910_RS10485	COG1067	ATP-dependent peptidase activity
DX910_RS10505	COG0254	rRNA binding
DX910_RS10520	COG1509	lysine 2,3-aminomutase activity
DX910_RS10525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DX910_RS10535	COG2879	small protein
DX910_RS10540	COG0714	Associated with various cellular activities
DX910_RS10615	COG0633	Ferredoxin
DX910_RS10650	COG1309	transcriptional regulator
DX910_RS10815	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DX910_RS10820	COG2116	formate transmembrane transporter activity
DX910_RS10825	COG0515	serine threonine protein kinase
DX910_RS10855	COG3657	addiction module killer protein
DX910_RS10860	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DX910_RS11025	COG2826	transposase and inactivated derivatives, IS30 family
DX910_RS11065	COG1741	Belongs to the pirin family
DX910_RS11080	COG0446	pyridine nucleotide-disulphide oxidoreductase
DX910_RS11080	COG1902	pentaerythritol trinitrate reductase activity
DX910_RS11090	COG0582	viral genome integration into host DNA
DX910_RS11100	COG4115	mRNA cleavage
DX910_RS11105	COG2161	toxin-antitoxin pair type II binding
DX910_RS11210	COG2205	protein histidine kinase activity
DX910_RS11225	COG2132	Multicopper oxidase
DX910_RS11380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DX910_RS11440	COG0642	Histidine kinase
DX910_RS11455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DX910_RS11485	COG1629	transport
DX910_RS11530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DX910_RS11535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DX910_RS11535	COG4451	ribulose bisphosphate carboxylase, small
DX910_RS11540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DX910_RS11545	COG1469	GTP cyclohydrolase I activity
DX910_RS11560	COG0523	cobalamin synthesis protein
DX910_RS11565	COG1414	Transcriptional regulator
DX910_RS11570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DX910_RS11575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DX910_RS11580	COG0183	Belongs to the thiolase family
DX910_RS11585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DX910_RS11590	COG0596	Alpha beta hydrolase
DX910_RS11600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DX910_RS11605	COG3485	protocatechuate 3,4-dioxygenase
DX910_RS11610	COG3485	protocatechuate 3,4-dioxygenase
DX910_RS11615	COG0710	3-dehydroquinate dehydratase activity
DX910_RS11625	COG3659	wide pore channel activity
DX910_RS11640	COG2351	hydroxyisourate hydrolase activity
DX910_RS11645	COG2233	PERMEase
DX910_RS11665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DX910_RS11675	COG4266	Belongs to the allantoicase family
DX910_RS11705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DX910_RS11720	COG0583	DNA-binding transcription factor activity
DX910_RS11730	COG2188	Transcriptional regulator
DX910_RS11755	COG0010	Belongs to the arginase family
DX910_RS11760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DX910_RS11780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DX910_RS11790	COG0243	molybdopterin cofactor binding
DX910_RS11795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DX910_RS11800	COG2837	iron assimilation
DX910_RS11815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DX910_RS11820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DX910_RS11825	COG0745	RESPONSE REGULATOR receiver
DX910_RS11830	COG5002	protein histidine kinase activity
DX910_RS11855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DX910_RS11865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DX910_RS11870	COG0642	Histidine kinase
DX910_RS11890	COG1309	transcriptional regulator
DX910_RS11910	COG2072	flavoprotein involved in K transport
DX910_RS11915	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DX910_RS11920	COG1560	Kdo2-lipid A biosynthetic process
DX910_RS11925	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DX910_RS11930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DX910_RS11935	COG4770	biotin carboxylase activity
DX910_RS11940	COG0501	Belongs to the peptidase M48B family
DX910_RS11950	COG1765	OsmC-like protein
DX910_RS12030	COG0308	aminopeptidase N
DX910_RS12045	COG1714	RDD family
DX910_RS12055	COG0475	glutathione-regulated potassium exporter activity
DX910_RS12055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DX910_RS12060	COG3135	benzoate transporter
DX910_RS12070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DX910_RS12125	COG0316	Belongs to the HesB IscA family
DX910_RS12130	COG0822	iron-sulfur transferase activity
DX910_RS12160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DX910_RS12175	COG2137	regulation of response to DNA damage stimulus
DX910_RS12185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DX910_RS12190	COG1011	Hydrolase
DX910_RS12215	COG0268	Binds directly to 16S ribosomal RNA
DX910_RS12220	COG0702	epimerase
DX910_RS12225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DX910_RS12240	COG0183	Belongs to the thiolase family
DX910_RS12255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DX910_RS12285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DX910_RS12290	COG0583	DNA-binding transcription factor activity
DX910_RS12295	COG0424	maF-like protein
DX910_RS12350	COG1286	toxin biosynthetic process
DX910_RS12395	COG3634	alkyl hydroperoxide reductase activity
DX910_RS12430	COG0436	Aminotransferase
DX910_RS12435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DX910_RS12440	COG0386	Belongs to the glutathione peroxidase family
DX910_RS12450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DX910_RS12465	COG1522	sequence-specific DNA binding
DX910_RS12475	COG0436	Aminotransferase
DX910_RS12500	COG1253	flavin adenine dinucleotide binding
DX910_RS12505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DX910_RS12520	COG0012	GTP binding
DX910_RS12525	COG2011	ABC-type metal ion transport system permease component
DX910_RS12530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DX910_RS12535	COG1464	Belongs to the NlpA lipoprotein family
DX910_RS12565	COG2195	Cleaves the N-terminal amino acid of tripeptides
DX910_RS12570	COG0430	RNA-3'-phosphate cyclase activity
DX910_RS12585	COG1690	Belongs to the RtcB family
DX910_RS12600	COG1234	tRNA 3'-trailer cleavage
DX910_RS12605	COG4650	regulator
DX910_RS12650	COG2363	Small membrane protein
DX910_RS12670	COG0513	Belongs to the DEAD box helicase family
DX910_RS12680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DX910_RS12695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DX910_RS12710	COG1475	DNA binding
DX910_RS12715	COG0811	peptide transport
DX910_RS12725	COG1132	(ABC) transporter
DX910_RS12730	COG1663	tetraacyldisaccharide 4'-kinase activity
DX910_RS12755	COG0084	hydrolase, TatD family'
DX910_RS12820	COG0776	regulation of translation
DX910_RS12835	COG2431	L-lysine efflux transmembrane transporter activity
DX910_RS12850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DX910_RS12855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DX910_RS12895	COG0024	Methionine aminopeptidase
DX910_RS12900	COG0583	DNA-binding transcription factor activity
DX910_RS12910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DX910_RS12915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DX910_RS12920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DX910_RS12920	COG0517	IMP dehydrogenase activity
DX910_RS12945	COG0552	protein localization to endoplasmic reticulum
DX910_RS12970	COG4890	Cyd operon protein YbgT
DX910_RS12975	COG1294	oxidase, subunit
DX910_RS13000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DX910_RS13020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DX910_RS13025	COG0569	domain protein
DX910_RS13030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DX910_RS13035	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DX910_RS13070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DX910_RS13075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DX910_RS13080	COG0542	response to heat
DX910_RS13090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DX910_RS13105	COG1902	pentaerythritol trinitrate reductase activity
DX910_RS13105	COG0446	pyridine nucleotide-disulphide oxidoreductase
DX910_RS13140	COG0148	phosphopyruvate hydratase activity
DX910_RS13145	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DX910_RS13200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DX910_RS13225	COG1802	Transcriptional regulator
DX910_RS13235	COG2207	Transcriptional regulator
DX910_RS13240	COG1063	alcohol dehydrogenase
DX910_RS13250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DX910_RS13290	COG1944	ATP diphosphatase activity
DX910_RS13310	COG1522	sequence-specific DNA binding
DX910_RS13330	COG0864	Transcriptional regulator
DX910_RS13335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DX910_RS13345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DX910_RS13350	COG1595	DNA-templated transcription, initiation
DX910_RS13410	COG0583	DNA-binding transcription factor activity
DX910_RS13420	COG4770	biotin carboxylase activity
DX910_RS13425	COG1024	Enoyl-CoA hydratase
DX910_RS13430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DX910_RS13440	COG1309	transcriptional regulator
DX910_RS13460	COG2814	Major facilitator Superfamily
DX910_RS13490	COG0583	DNA-binding transcription factor activity
DX910_RS13500	COG4774	siderophore transport
DX910_RS13525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DX910_RS13530	COG4628	conserved protein (DUF2132)
DX910_RS13615	COG2249	NAD(P)H dehydrogenase (quinone) activity
DX910_RS13625	COG3706	GGDEF domain
DX910_RS13645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DX910_RS13665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DX910_RS13710	COG0537	adenosine 5'-monophosphoramidase activity
DX910_RS13735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DX910_RS13755	COG0730	response to heat
DX910_RS13760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DX910_RS13770	COG4771	TonB-dependent receptor
DX910_RS13795	COG0406	alpha-ribazole phosphatase activity
DX910_RS13800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DX910_RS13815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DX910_RS13875	COG1960	acyl-CoA dehydrogenase activity
DX910_RS13895	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DX910_RS13900	COG2207	Transcriptional regulator
DX910_RS13905	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DX910_RS13915	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DX910_RS13940	COG0575	Belongs to the CDS family
DX910_RS13945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DX910_RS13955	COG0528	UMP kinase activity
DX910_RS13965	COG3852	Histidine kinase
DX910_RS13970	COG2204	response regulator
DX910_RS13975	COG1309	transcriptional regulator
DX910_RS14040	COG0697	spore germination
DX910_RS14045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DX910_RS14060	COG0521	Mo-molybdopterin cofactor biosynthetic process
DX910_RS14060	COG0315	cyclic pyranopterin monophosphate synthase activity
DX910_RS14075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DX910_RS14080	COG0243	molybdopterin cofactor binding
DX910_RS14095	COG0243	molybdopterin cofactor binding
DX910_RS14100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DX910_RS14105	COG2146	nitrite reductase [NAD(P)H] activity
DX910_RS14105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DX910_RS14120	COG1116	anion transmembrane transporter activity
DX910_RS14120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DX910_RS14135	COG0439	Biotin carboxylase
DX910_RS14160	COG0069	glutamate synthase activity
DX910_RS14180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DX910_RS14185	COG3038	cytochrome b561
DX910_RS14190	COG1454	alcohol dehydrogenase
DX910_RS14195	COG0824	Thioesterase
DX910_RS14205	COG2850	peptidyl-arginine hydroxylation
DX910_RS14225	COG0640	Transcriptional regulator
DX910_RS14250	COG0668	transmembrane transport
DX910_RS14260	COG1132	(ABC) transporter
DX910_RS14280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DX910_RS14290	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DX910_RS14290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DX910_RS14290	COG0506	proline dehydrogenase activity
DX910_RS14295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DX910_RS14300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DX910_RS14310	COG3698	Phosphodiester glycosidase
DX910_RS14325	COG3153	acetyltransferase
DX910_RS14330	COG2353	YceI-like domain
DX910_RS14345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DX910_RS14350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DX910_RS14365	COG3042	response to heat
DX910_RS14375	COG1278	Cold shock
DX910_RS14380	COG1278	Cold shock
DX910_RS14425	COG3539	Fimbrial protein
DX910_RS14580	COG4416	COG NOG18757 non supervised orthologous group
DX910_RS14590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DX910_RS14600	COG2369	cell adhesion
DX910_RS14770	COG1960	acyl-CoA dehydrogenase activity
DX910_RS14775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DX910_RS14805	COG3139	Protein of unknown function (DUF1315)
DX910_RS14825	COG0494	nUDIX hydrolase
DX910_RS14850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DX910_RS14855	COG1720	tRNA m6t6A37 methyltransferase activity
DX910_RS14890	COG0583	DNA-binding transcription factor activity
DX910_RS14895	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DX910_RS14910	COG4607	ABC-type enterochelin transport system periplasmic component
DX910_RS14915	COG4604	ABC transporter, ATP-binding protein
DX910_RS14920	COG4605	iron ion homeostasis
DX910_RS14925	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DX910_RS14935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DX910_RS14970	COG0729	surface antigen
DX910_RS14995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DX910_RS15015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DX910_RS15025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DX910_RS15110	COG3659	wide pore channel activity
DX910_RS15130	COG0583	DNA-binding transcription factor activity
DX910_RS15135	COG1131	(ABC) transporter
DX910_RS15140	COG0842	Transport permease protein
DX910_RS15155	COG0772	Belongs to the SEDS family
DX910_RS15185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DX910_RS15205	COG0450	alkyl hydroperoxide reductase
DX910_RS15215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DX910_RS15255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DX910_RS15270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DX910_RS15280	COG0531	amino acid
DX910_RS15285	COG4303	Ethanolamine ammonia lyase large subunit
DX910_RS15290	COG4302	ethanolamine ammonia-lyase activity
DX910_RS15295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DX910_RS15295	COG0519	Catalyzes the synthesis of GMP from XMP
DX910_RS15300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DX910_RS15310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DX910_RS15320	COG2249	NAD(P)H dehydrogenase (quinone) activity
DX910_RS15330	COG0697	spore germination
DX910_RS15335	COG1923	regulation of RNA biosynthetic process
DX910_RS15345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DX910_RS15350	COG0802	atpase or kinase
DX910_RS15380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DX910_RS15385	COG3300	MHYT domain
DX910_RS15385	COG5001	Diguanylate cyclase
DX910_RS15405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DX910_RS15410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DX910_RS15415	COG1845	cytochrome c oxidase, subunit III
DX910_RS15420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DX910_RS15445	COG2249	NAD(P)H dehydrogenase (quinone) activity
DX910_RS15450	COG1733	regulation of RNA biosynthetic process
DX910_RS15455	COG0305	Participates in initiation and elongation during chromosome replication
DX910_RS15460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DX910_RS15475	COG1305	Transglutaminase-like
DX910_RS15485	COG2308	Evidence 4 Homologs of previously reported genes of
DX910_RS15495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DX910_RS15510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DX910_RS15520	COG0527	aspartate kinase activity
DX910_RS15530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DX910_RS15540	COG3038	cytochrome b561
DX910_RS15545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DX910_RS15615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DX910_RS15620	COG0138	bifunctional purine biosynthesis protein purh
DX910_RS15625	COG0151	Belongs to the GarS family
DX910_RS15630	COG1464	Belongs to the NlpA lipoprotein family
DX910_RS15635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DX910_RS15640	COG2011	ABC-type metal ion transport system permease component
DX910_RS15665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DX910_RS15670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DX910_RS15675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DX910_RS15700	COG0052	Belongs to the universal ribosomal protein uS2 family
DX910_RS15705	COG0024	Methionine aminopeptidase
DX910_RS15715	COG2223	nitrite transmembrane transporter activity
DX910_RS15725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DX910_RS15730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DX910_RS15735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DX910_RS15740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DX910_RS15775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DX910_RS15780	COG3161	chorismate lyase activity
DX910_RS15785	COG0174	glutamine synthetase
DX910_RS15790	COG0512	Glutamine amidotransferase of anthranilate synthase
DX910_RS15795	COG1823	symporter activity
DX910_RS15800	COG3217	Mosc domain protein beta barrel domain protein
DX910_RS15800	COG0633	Ferredoxin
DX910_RS15825	COG0302	gtp cyclohydrolase
DX910_RS15860	COG5001	Diguanylate cyclase
DX910_RS15860	COG4251	negative regulation of phosphorylation
DX910_RS15860	COG3706	GGDEF domain
DX910_RS15860	COG2203	Gaf domain
DX910_RS15870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DX910_RS15885	COG4172	Belongs to the ABC transporter superfamily
DX910_RS15890	COG4239	(ABC) transporter, permease
DX910_RS15895	COG4174	ABC transporter (Permease)
DX910_RS15900	COG4166	transmembrane transport
DX910_RS15905	COG0741	lytic transglycosylase activity
DX910_RS15905	COG0741	lytic transglycosylase activity
DX910_RS15905	COG1388	LysM domain
DX910_RS15905	COG1388	LysM domain
DX910_RS15910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DX910_RS15920	COG2816	NAD+ diphosphatase activity
DX910_RS15950	COG0583	DNA-binding transcription factor activity
DX910_RS15955	COG1279	arginine transmembrane transporter activity
DX910_RS15965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DX910_RS15970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DX910_RS15975	COG0006	proline dipeptidase activity
DX910_RS16005	COG2217	Heavy metal translocating P-type atpase
DX910_RS16035	COG3384	dioxygenase
DX910_RS16045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DX910_RS16080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DX910_RS16110	COG0742	ribosomal rna small subunit methyltransferase
DX910_RS16135	COG0616	signal peptide processing
DX910_RS16140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DX910_RS16165	COG0076	glutamate decarboxylase activity
DX910_RS16170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DX910_RS16220	COG0783	Belongs to the Dps family
DX910_RS16230	COG0564	pseudouridine synthase activity
DX910_RS16245	COG0352	thiamine-phosphate diphosphorylase activity
DX910_RS16280	COG0384	phenazine biosynthesis protein PhzF
DX910_RS16320	COG1686	Belongs to the peptidase S11 family
DX910_RS16325	COG1252	NADH dehydrogenase
DX910_RS16375	COG1271	oxidase subunit
DX910_RS16400	COG0705	Rhomboid family
DX910_RS16400	COG0457	Tetratricopeptide repeat
DX910_RS16415	COG4181	ATPase activity
DX910_RS16425	COG0456	acetyltransferase
DX910_RS16465	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DX910_RS16495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DX910_RS16500	COG1597	lipid kinase activity
DX910_RS16545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DX910_RS16600	COG4681	YaeQ
DX910_RS16605	COG0523	cobalamin synthesis protein
DX910_RS16615	COG1607	acyl-coa hydrolase
DX910_RS16640	COG1024	Enoyl-CoA hydratase
DX910_RS16645	COG1012	belongs to the aldehyde dehydrogenase family
DX910_RS16655	COG1960	acyl-CoA dehydrogenase activity
DX910_RS16675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DX910_RS16680	COG1414	Transcriptional regulator
DX910_RS16685	COG0281	malic enzyme
DX910_RS16690	COG0833	amino acid
DX910_RS16705	COG1012	belongs to the aldehyde dehydrogenase family
DX910_RS16715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DX910_RS16720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DX910_RS16750	COG3173	Aminoglycoside phosphotransferase
DX910_RS16755	COG0488	(ABC) transporter
DX910_RS16825	COG1475	DNA binding
DX910_RS17015	COG0741	lytic transglycosylase activity
DX910_RS17050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DX910_RS17130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DX910_RS17155	COG2801	Transposase and inactivated derivatives
DX910_RS17170	COG2433	Pfam Transposase IS66
DX910_RS17190	COG3293	Transposase
DX910_RS17255	COG2963	transposase activity
DX910_RS17265	COG4372	Transposase
DX910_RS17275	COG2963	transposase activity
DX910_RS17285	COG4372	Transposase
DX910_RS17290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DX910_RS17295	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DX910_RS17300	COG3657	addiction module killer protein
DX910_RS17385	COG1525	nuclease
DX910_RS17415	COG4372	Transposase
DX910_RS17425	COG2963	transposase activity