locus-tag	class	description
G0027_RS00050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0027_RS00055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G0027_RS00070	COG1113	amino acid transport
G0027_RS00080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0027_RS00090	COG2814	Major facilitator Superfamily
G0027_RS00110	COG1132	(ABC) transporter
G0027_RS00125	COG0668	transmembrane transport
G0027_RS00130	COG3122	Protein conserved in bacteria
G0027_RS00150	COG0640	Transcriptional regulator
G0027_RS00160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0027_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0027_RS00165	COG1116	anion transmembrane transporter activity
G0027_RS00175	COG2223	nitrite transmembrane transporter activity
G0027_RS00180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_RS00185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_RS00190	COG0243	molybdopterin cofactor binding
G0027_RS00200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G0027_RS00215	COG0521	Mo-molybdopterin cofactor biosynthetic process
G0027_RS00215	COG0315	cyclic pyranopterin monophosphate synthase activity
G0027_RS00230	COG4149	molybdate abc transporter
G0027_RS00235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G0027_RS00240	COG0583	DNA-binding transcription factor activity
G0027_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_RS00265	COG0183	Belongs to the thiolase family
G0027_RS00270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_RS00275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0027_RS00285	COG0583	DNA-binding transcription factor activity
G0027_RS00290	COG2814	Major facilitator Superfamily
G0027_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS00330	COG2223	nitrite transmembrane transporter activity
G0027_RS00340	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
G0027_RS00345	COG2116	formate transmembrane transporter activity
G0027_RS00350	COG0515	serine threonine protein kinase
G0027_RS00355	COG0644	oxidoreductase
G0027_RS00355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0027_RS00365	COG1960	acyl-CoA dehydrogenase activity
G0027_RS00370	COG1960	acyl-CoA dehydrogenase activity
G0027_RS00375	COG2814	Major facilitator Superfamily
G0027_RS00380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0027_RS00385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_RS00390	COG2814	Major facilitator Superfamily
G0027_RS00400	COG2814	Major facilitator Superfamily
G0027_RS00405	COG1024	Enoyl-CoA hydratase
G0027_RS00410	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_RS00415	COG0183	Belongs to the thiolase family
G0027_RS00425	COG0235	Class ii aldolase
G0027_RS00430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0027_RS00435	COG1024	Enoyl-CoA hydratase
G0027_RS00445	COG1960	acyl-CoA dehydrogenase activity
G0027_RS00460	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS00470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0027_RS00475	COG2814	Major facilitator Superfamily
G0027_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS00490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G0027_RS00500	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS00530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_RS00560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G0027_RS00565	COG1309	transcriptional regulator
G0027_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
G0027_RS00600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G0027_RS00635	COG2885	chlorophyll binding
G0027_RS00645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G0027_RS00650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0027_RS00655	COG0730	response to heat
G0027_RS00660	COG3293	Transposase
G0027_RS00700	COG2801	Transposase and inactivated derivatives
G0027_RS00790	COG0596	Alpha beta hydrolase
G0027_RS00825	COG0511	ligase activity, forming carbon-carbon bonds
G0027_RS00830	COG0439	Biotin carboxylase
G0027_RS00845	COG2814	Major facilitator Superfamily
G0027_RS00850	COG3038	cytochrome b561
G0027_RS00885	COG1546	Belongs to the CinA family
G0027_RS00885	COG1058	Belongs to the CinA family
G0027_RS00895	COG0372	Belongs to the citrate synthase family
G0027_RS00930	COG0542	response to heat
G0027_RS00935	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G0027_RS00965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G0027_RS00975	COG0569	domain protein
G0027_RS00980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G0027_RS01000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G0027_RS01010	COG1585	Membrane protein implicated in regulation of membrane protease activity
G0027_RS01025	COG1294	oxidase, subunit
G0027_RS01030	COG4890	Cyd operon protein YbgT
G0027_RS01065	COG1960	acyl-CoA dehydrogenase activity
G0027_RS01070	COG1960	acyl-CoA dehydrogenase activity
G0027_RS01080	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0027_RS01085	COG2207	Transcriptional regulator
G0027_RS01090	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0027_RS01095	COG0730	response to heat
G0027_RS01100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0027_RS01130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0027_RS01150	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0027_RS01165	COG0575	Belongs to the CDS family
G0027_RS01170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G0027_RS01175	COG0233	cytoplasmic translational termination
G0027_RS01190	COG3852	Histidine kinase
G0027_RS01205	COG0583	DNA-binding transcription factor activity
G0027_RS01235	COG1253	flavin adenine dinucleotide binding
G0027_RS01255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G0027_RS01260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G0027_RS01275	COG2431	L-lysine efflux transmembrane transporter activity
G0027_RS01280	COG0284	orotidine-5'-phosphate decarboxylase activity
G0027_RS01290	COG0776	regulation of translation
G0027_RS01320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G0027_RS01355	COG0084	hydrolase, TatD family'
G0027_RS01375	COG1663	tetraacyldisaccharide 4'-kinase activity
G0027_RS01380	COG1132	(ABC) transporter
G0027_RS01390	COG0811	peptide transport
G0027_RS01395	COG1475	DNA binding
G0027_RS01400	COG1192	Involved in chromosome partitioning
G0027_RS01410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G0027_RS01415	COG3178	'Phosphotransferase
G0027_RS01425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0027_RS01430	COG1923	regulation of RNA biosynthetic process
G0027_RS01440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G0027_RS01445	COG0802	atpase or kinase
G0027_RS01470	COG2707	UPF0756 membrane protein
G0027_RS01480	COG0583	DNA-binding transcription factor activity
G0027_RS01485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_RS01515	COG0519	Catalyzes the synthesis of GMP from XMP
G0027_RS01515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0027_RS01520	COG2353	YceI-like domain
G0027_RS01530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G0027_RS01535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G0027_RS01575	COG1254	Belongs to the acylphosphatase family
G0027_RS01580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G0027_RS01580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G0027_RS01585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G0027_RS01605	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS01615	COG3327	negative regulation of DNA-templated transcription, initiation
G0027_RS01620	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G0027_RS01625	COG0183	Belongs to the thiolase family
G0027_RS01630	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_RS01635	COG1024	Enoyl-CoA hydratase
G0027_RS01650	COG0204	Acyl-transferase
G0027_RS01680	COG0012	GTP binding
G0027_RS01690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G0027_RS01705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G0027_RS01715	COG0386	Belongs to the glutathione peroxidase family
G0027_RS01720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G0027_RS01725	COG0436	Aminotransferase
G0027_RS01730	COG2755	lipolytic protein G-D-S-L family
G0027_RS01730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G0027_RS01770	COG0515	serine threonine protein kinase
G0027_RS01770	COG2815	serine threonine protein kinase
G0027_RS01800	COG1610	YqeY-like protein
G0027_RS01815	COG4783	chaperone-mediated protein folding
G0027_RS01880	COG0513	Belongs to the DEAD box helicase family
G0027_RS01900	COG2363	Small membrane protein
G0027_RS01920	COG0659	secondary active sulfate transmembrane transporter activity
G0027_RS01930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G0027_RS01950	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS01955	COG1309	transcriptional regulator
G0027_RS01960	COG1960	acyl-CoA dehydrogenase activity
G0027_RS01965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G0027_RS01970	COG1024	Enoyl-CoA hydratase
G0027_RS01975	COG4770	biotin carboxylase activity
G0027_RS01990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_RS02005	COG0540	Belongs to the ATCase OTCase family
G0027_RS02025	COG1765	OsmC-like protein
G0027_RS02035	COG0667	Aldo Keto reductase
G0027_RS02050	COG0501	Belongs to the peptidase M48B family
G0027_RS02055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G0027_RS02070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G0027_RS02080	COG0527	aspartate kinase activity
G0027_RS02090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G0027_RS02100	COG1215	transferase activity, transferring glycosyl groups
G0027_RS02110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G0027_RS02115	COG2252	PERMEase
G0027_RS02150	COG2879	small protein
G0027_RS02155	COG1966	Carbon starvation protein
G0027_RS02160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G0027_RS02165	COG1509	lysine 2,3-aminomutase activity
G0027_RS02200	COG1067	ATP-dependent peptidase activity
G0027_RS02205	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G0027_RS02210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G0027_RS02215	COG0583	DNA-binding transcription factor activity
G0027_RS02225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G0027_RS02240	COG1686	Belongs to the peptidase S11 family
G0027_RS02245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G0027_RS02280	COG0616	signal peptide processing
G0027_RS02285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G0027_RS02295	COG0573	inorganic phosphate transmembrane transporter activity
G0027_RS02305	COG0076	glutamate decarboxylase activity
G0027_RS02310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G0027_RS02350	COG3385	transposase activity
G0027_RS02360	COG4372	Transposase
G0027_RS02465	COG3617	BRO family, N-terminal domain
G0027_RS02490	COG0582	viral genome integration into host DNA
G0027_RS02495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G0027_RS02505	COG2814	Major facilitator Superfamily
G0027_RS02510	COG1733	regulation of RNA biosynthetic process
G0027_RS02515	COG0702	epimerase
G0027_RS02545	COG0556	nucleotide-excision repair
G0027_RS02555	COG3300	MHYT domain
G0027_RS02555	COG5001	Diguanylate cyclase
G0027_RS02580	COG0436	Aminotransferase
G0027_RS02605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G0027_RS02610	COG1381	Involved in DNA repair and RecF pathway recombination
G0027_RS02620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G0027_RS02625	COG0571	ribonuclease III activity
G0027_RS02635	COG0681	Belongs to the peptidase S26 family
G0027_RS02650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G0027_RS02660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G0027_RS02675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G0027_RS02685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0027_RS02700	COG4208	sulfate ABC transporter
G0027_RS02705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G0027_RS02710	COG0583	DNA-binding transcription factor activity
G0027_RS02730	COG0602	queuosine metabolic process
G0027_RS02735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G0027_RS02745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G0027_RS02750	COG2353	YceI-like domain
G0027_RS02755	COG1051	belongs to the nudix hydrolase family
G0027_RS02755	COG1056	cytidyltransferase-related domain
G0027_RS02760	COG1024	Enoyl-CoA hydratase
G0027_RS02765	COG0778	Nitroreductase
G0027_RS02780	COG0047	phosphoribosylformylglycinamidine synthase activity
G0027_RS02780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G0027_RS02800	COG2310	stress, protein
G0027_RS02830	COG1358	cellular component organization or biogenesis
G0027_RS02860	COG2255	four-way junction helicase activity
G0027_RS02870	COG0824	Thioesterase
G0027_RS02890	COG0823	Involved in the tonB-independent uptake of proteins
G0027_RS02910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0027_RS02940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0027_RS02945	COG0628	permease
G0027_RS02950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G0027_RS02955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G0027_RS02975	COG2333	competence protein COMEC
G0027_RS02975	COG0658	competence protein
G0027_RS02980	COG1136	(ABC) transporter
G0027_RS02985	COG4591	ABC-type transport system involved in lipoprotein release permease component
G0027_RS03000	COG1671	Belongs to the UPF0178 family
G0027_RS03045	COG1280	lysine exporter protein (LysE YggA)
G0027_RS03050	COG1522	sequence-specific DNA binding
G0027_RS03060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G0027_RS03075	COG0019	diaminopimelate decarboxylase activity
G0027_RS03085	COG1113	amino acid transport
G0027_RS03090	COG1115	amino acid carrier protein
G0027_RS03110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G0027_RS03115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G0027_RS03150	COG0583	DNA-binding transcription factor activity
G0027_RS03160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G0027_RS03170	COG0174	glutamine synthetase
G0027_RS03175	COG0512	Glutamine amidotransferase of anthranilate synthase
G0027_RS03195	COG0302	gtp cyclohydrolase
G0027_RS03205	COG3706	GGDEF domain
G0027_RS03220	COG3739	integral membrane protein
G0027_RS03225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G0027_RS03235	COG1741	Belongs to the pirin family
G0027_RS03240	COG3842	ATPase activity
G0027_RS03245	COG1840	ABC-type Fe3 transport system, periplasmic component
G0027_RS03270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G0027_RS03300	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G0027_RS03310	COG2184	nucleotidyltransferase activity
G0027_RS03370	COG0582	viral genome integration into host DNA
G0027_RS03380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0027_RS03400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0027_RS03405	COG1074	ATP-dependent DNA helicase activity
G0027_RS03410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G0027_RS03420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G0027_RS03430	COG4372	Transposase
G0027_RS03470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G0027_RS03480	COG1061	Type III restriction enzyme res subunit
G0027_RS03485	COG1002	Type II restriction enzyme, methylase subunits
G0027_RS03520	COG4372	Transposase
G0027_RS03535	COG4372	Transposase
G0027_RS03575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G0027_RS03585	COG0037	tRNA processing
G0027_RS03590	COG0741	lytic transglycosylase activity
G0027_RS03590	COG0739	heme binding
G0027_RS03590	COG1196	nuclear chromosome segregation
G0027_RS03595	COG0501	Belongs to the peptidase M48B family
G0027_RS03605	COG2239	Acts as a magnesium transporter
G0027_RS03615	COG0584	glycerophosphoryl diester phosphodiesterase
G0027_RS03640	COG1597	lipid kinase activity
G0027_RS03660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G0027_RS03695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G0027_RS03705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0027_RS03715	COG1534	Rna-binding protein
G0027_RS03730	COG0505	Belongs to the CarA family
G0027_RS03745	COG0415	Belongs to the DNA photolyase family
G0027_RS03750	COG0110	maltose O-acetyltransferase activity
G0027_RS03755	COG0589	response to stress
G0027_RS03765	COG2321	neutral zinc metallopeptidase
G0027_RS03770	COG2354	Protein conserved in bacteria
G0027_RS03785	COG2268	Band 7 protein
G0027_RS03795	COG1215	transferase activity, transferring glycosyl groups
G0027_RS03800	COG0726	polysaccharide deacetylase
G0027_RS03800	COG1649	PFAM Uncharacterised BCR, COG1649
G0027_RS03810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G0027_RS03820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G0027_RS03835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G0027_RS03840	COG1053	succinate dehydrogenase
G0027_RS03845	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G0027_RS03860	COG2072	flavoprotein involved in K transport
G0027_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS03875	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G0027_RS03890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0027_RS03890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G0027_RS03920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0027_RS03930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G0027_RS03945	COG0564	pseudouridine synthase activity
G0027_RS03955	COG0358	DNA primase activity
G0027_RS03970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G0027_RS04000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G0027_RS04040	COG0586	Pfam SNARE associated Golgi protein
G0027_RS04065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G0027_RS04075	COG0321	lipoyl(octanoyl) transferase activity
G0027_RS04090	COG0531	amino acid
G0027_RS04095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G0027_RS04100	COG1648	precorrin-2 dehydrogenase activity
G0027_RS04100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G0027_RS04105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G0027_RS04115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G0027_RS04140	COG0671	phosphoesterase, PA-phosphatase related
G0027_RS04145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_RS04155	COG1538	Outer membrane efflux protein
G0027_RS04165	COG0393	Putative heavy-metal-binding
G0027_RS04170	COG0393	Putative heavy-metal-binding
G0027_RS04185	COG0525	valine-tRNA ligase activity
G0027_RS04215	COG2323	membrane
G0027_RS04225	COG0765	amino acid transport
G0027_RS04230	COG0765	amino acid transport
G0027_RS04235	COG1126	abc transporter atp-binding protein
G0027_RS04240	COG3338	carbonate dehydratase activity
G0027_RS04255	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0027_RS04270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0027_RS04275	COG2205	protein histidine kinase activity
G0027_RS04280	COG0745	RESPONSE REGULATOR receiver
G0027_RS04290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G0027_RS04320	COG1652	LysM domain
G0027_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS04345	COG1399	metal-binding, possibly nucleic acid-binding protein
G0027_RS04350	COG3101	peptidyl-lysine hydroxylation
G0027_RS04355	COG0009	L-threonylcarbamoyladenylate synthase
G0027_RS04365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G0027_RS04370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G0027_RS04385	COG4106	trans-aconitate 2-methyltransferase activity
G0027_RS04400	COG0596	Alpha beta hydrolase
G0027_RS04400	COG2226	methyltransferase
G0027_RS04400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_RS04405	COG2193	ferroxidase activity
G0027_RS04410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G0027_RS04415	COG3115	cell septum assembly
G0027_RS04420	COG1196	nuclear chromosome segregation
G0027_RS04430	COG0730	response to heat
G0027_RS04450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G0027_RS04480	COG2801	Transposase and inactivated derivatives
G0027_RS04485	COG2801	Transposase and inactivated derivatives
G0027_RS04500	COG0628	permease
G0027_RS04510	COG2824	Alkylphosphonate utilization operon protein PhnA
G0027_RS04515	COG3189	MarR family transcriptional regulator
G0027_RS04530	COG0564	pseudouridine synthase activity
G0027_RS04565	COG0354	folic acid binding
G0027_RS04595	COG0363	glucosamine-6-phosphate deaminase activity
G0027_RS04605	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G0027_RS04610	COG1877	trehalose-phosphatase activity
G0027_RS04620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0027_RS04625	COG1970	mechanosensitive ion channel activity
G0027_RS04630	COG1217	gtp-binding protein TYPA
G0027_RS04635	COG2233	PERMEase
G0027_RS04645	COG0833	amino acid
G0027_RS04665	COG0183	Belongs to the thiolase family
G0027_RS04680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_RS04685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0027_RS04690	COG2207	Transcriptional regulator
G0027_RS04695	COG0183	Belongs to the thiolase family
G0027_RS04700	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_RS04700	COG1024	Enoyl-CoA hydratase
G0027_RS04725	COG1272	protein, Hemolysin III
G0027_RS04730	COG0477	Major facilitator Superfamily
G0027_RS04740	COG1408	metallophosphoesterase
G0027_RS04745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0027_RS04755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G0027_RS04785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G0027_RS04790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G0027_RS04795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G0027_RS04805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G0027_RS04810	COG0625	glutathione transferase activity
G0027_RS04815	COG2969	positive regulation of protein catabolic process
G0027_RS04870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0027_RS04915	COG0037	tRNA processing
G0027_RS04925	COG0248	Ppx GppA phosphatase
G0027_RS04950	COG0072	phenylalanine-tRNA ligase activity
G0027_RS04985	COG1238	metal cluster binding
G0027_RS04990	COG0625	glutathione transferase activity
G0027_RS05005	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS05010	COG3028	Belongs to the UPF0307 family
G0027_RS05020	COG1660	Displays ATPase and GTPase activities
G0027_RS05035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G0027_RS05040	COG0617	tRNA 3'-terminal CCA addition
G0027_RS05045	COG1555	photosystem II stabilization
G0027_RS05050	COG3956	TIGRFAM MazG family protein
G0027_RS05065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0027_RS05075	COG0124	histidyl-tRNA synthetase
G0027_RS05105	COG2975	iron-sulfur cluster assembly
G0027_RS05145	COG0440	acetolactate synthase activity
G0027_RS05150	COG0028	Belongs to the TPP enzyme family
G0027_RS05180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_RS05185	COG1136	(ABC) transporter
G0027_RS05185	COG0577	efflux transmembrane transporter activity
G0027_RS05190	COG1538	Outer membrane efflux protein
G0027_RS05205	COG2826	transposase and inactivated derivatives, IS30 family
G0027_RS05230	COG1324	tolerance protein
G0027_RS05235	COG0673	inositol 2-dehydrogenase activity
G0027_RS05255	COG2826	transposase and inactivated derivatives, IS30 family
G0027_RS05280	COG1324	tolerance protein
G0027_RS05330	COG1324	tolerance protein
G0027_RS05355	COG2826	transposase and inactivated derivatives, IS30 family
G0027_RS05380	COG1324	tolerance protein
G0027_RS05385	COG0673	inositol 2-dehydrogenase activity
G0027_RS05405	COG2826	transposase and inactivated derivatives, IS30 family
G0027_RS05420	COG1388	LysM domain
G0027_RS05420	COG3942	CHAP domain
G0027_RS05445	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G0027_RS05450	COG1162	GTPase activity
G0027_RS05460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G0027_RS05470	COG3385	transposase activity
G0027_RS05475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G0027_RS05485	COG3781	membrane
G0027_RS05490	COG0613	PHP domain protein
G0027_RS05500	COG2350	Protein conserved in bacteria
G0027_RS05520	COG1666	GTP binding
G0027_RS05530	COG1607	acyl-coa hydrolase
G0027_RS05595	COG1183	phosphatidylcholine synthase activity
G0027_RS05600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G0027_RS05640	COG1196	nuclear chromosome segregation
G0027_RS05640	COG0741	lytic transglycosylase activity
G0027_RS05640	COG0739	heme binding
G0027_RS05650	COG1702	phosphate starvation-inducible protein PhoH
G0027_RS05695	COG1295	ribonuclease BN
G0027_RS05725	COG0788	formyltetrahydrofolate deformylase activity
G0027_RS05750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G0027_RS05750	COG4651	solute:proton antiporter activity
G0027_RS05765	COG0724	RNA recognition motif
G0027_RS05770	COG0210	DNA helicase
G0027_RS05780	COG1929	Belongs to the glycerate kinase type-1 family
G0027_RS05810	COG2900	Belongs to the SlyX family
G0027_RS05815	COG0488	(ABC) transporter
G0027_RS05820	COG1560	Kdo2-lipid A biosynthetic process
G0027_RS05870	COG0473	3-isopropylmalate dehydrogenase activity
G0027_RS05885	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G0027_RS05900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G0027_RS05915	COG0494	nUDIX hydrolase
G0027_RS05935	COG1960	acyl-CoA dehydrogenase activity
G0027_RS05945	COG0753	catalase activity
G0027_RS05960	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0027_RS05965	COG3384	dioxygenase
G0027_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS05985	COG4638	Rieske (2fe-2S)
G0027_RS05990	COG0583	DNA-binding transcription factor activity
G0027_RS06015	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G0027_RS06020	COG3971	2-oxopent-4-enoate hydratase activity
G0027_RS06025	COG0546	phosphoglycolate phosphatase activity
G0027_RS06035	COG1530	ribonuclease E activity
G0027_RS06040	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS06065	COG1983	PspC domain protein
G0027_RS06070	COG0517	IMP dehydrogenase activity
G0027_RS06070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0027_RS06070	COG0617	tRNA 3'-terminal CCA addition
G0027_RS06080	COG0751	glycine-tRNA ligase activity
G0027_RS06125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G0027_RS06150	COG0493	'glutamate synthase
G0027_RS06150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0027_RS06160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G0027_RS06170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G0027_RS06185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G0027_RS06195	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0027_RS06195	COG0644	oxidoreductase
G0027_RS06210	COG2826	transposase and inactivated derivatives, IS30 family
G0027_RS06220	COG2826	transposase and inactivated derivatives, IS30 family
G0027_RS06245	COG0425	Belongs to the sulfur carrier protein TusA family
G0027_RS06250	COG4535	Mg2 and Co2 transporter CorC
G0027_RS06255	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G0027_RS06275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G0027_RS06285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G0027_RS06295	COG0789	Transcriptional regulator
G0027_RS06300	COG2841	Protein conserved in bacteria
G0027_RS06315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G0027_RS06320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_RS06325	COG1074	ATP-dependent DNA helicase activity
G0027_RS06330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G0027_RS06360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0027_RS06370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G0027_RS06385	COG2111	Na H antiporter
G0027_RS06385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0027_RS06390	COG1006	Multisubunit Na H antiporter MnhC subunit
G0027_RS06395	COG0651	ATP synthesis coupled electron transport
G0027_RS06400	COG1863	multisubunit Na H antiporter MnhE subunit
G0027_RS06405	COG2212	antiporter activity
G0027_RS06410	COG1320	monovalent cation:proton antiporter activity
G0027_RS06415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G0027_RS06425	COG0195	Participates in both transcription termination and antitermination
G0027_RS06430	COG0779	Required for maturation of 30S ribosomal subunits
G0027_RS06480	COG0237	dephospho-CoA kinase activity
G0027_RS06490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0027_RS06495	COG3123	guanosine phosphorylase activity
G0027_RS06500	COG0497	DNA recombination
G0027_RS06510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G0027_RS06525	COG1132	(ABC) transporter
G0027_RS06530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G0027_RS06540	COG0322	excinuclease ABC activity
G0027_RS06560	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_RS06560	COG1024	Enoyl-CoA hydratase
G0027_RS06570	COG2233	PERMEase
G0027_RS06580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G0027_RS06610	COG0326	Molecular chaperone. Has ATPase activity
G0027_RS06625	COG2056	Na+-H+ antiporter family
G0027_RS06645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G0027_RS06650	COG0085	RNA polymerase activity
G0027_RS06665	COG0081	regulation of translation
G0027_RS06750	COG0824	Thioesterase
G0027_RS06770	COG0181	hydroxymethylbilane synthase activity
G0027_RS06780	COG3275	phosphorelay sensor kinase activity
G0027_RS06825	COG0494	nUDIX hydrolase
G0027_RS06830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G0027_RS06835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G0027_RS06840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0027_RS06850	COG0772	Belongs to the SEDS family
G0027_RS06875	COG4974	Belongs to the 'phage' integrase family
G0027_RS06890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G0027_RS06900	COG2197	response regulator
G0027_RS06915	COG0793	Belongs to the peptidase S41A family
G0027_RS06920	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G0027_RS06925	COG0795	lipopolysaccharide-transporting ATPase activity
G0027_RS06930	COG0795	lipopolysaccharide-transporting ATPase activity
G0027_RS06955	COG0586	Pfam SNARE associated Golgi protein
G0027_RS06970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0027_RS06970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0027_RS06980	COG0004	ammonium transporteR
G0027_RS06985	COG0347	Belongs to the P(II) protein family
G0027_RS06995	COG0606	chelatase, subunit chli
G0027_RS07010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G0027_RS07025	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_RS07035	COG0477	Major facilitator Superfamily
G0027_RS07040	COG2860	membrane
G0027_RS07050	COG1253	flavin adenine dinucleotide binding
G0027_RS07070	COG2814	Major facilitator Superfamily
G0027_RS07085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0027_RS07105	COG2814	Major facilitator Superfamily
G0027_RS07155	COG0758	DNA mediated transformation
G0027_RS07165	COG0697	spore germination
G0027_RS07170	COG0386	Belongs to the glutathione peroxidase family
G0027_RS07195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G0027_RS07245	COG1121	(ABC) transporter
G0027_RS07250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G0027_RS07260	COG2837	iron assimilation
G0027_RS07280	COG0281	malic enzyme
G0027_RS07320	COG1715	Restriction endonuclease
G0027_RS07325	COG0519	Catalyzes the synthesis of GMP from XMP
G0027_RS07325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0027_RS07330	COG2259	Doxx family
G0027_RS07335	COG0586	Pfam SNARE associated Golgi protein
G0027_RS07350	COG1192	Involved in chromosome partitioning
G0027_RS07360	COG0271	Belongs to the BolA IbaG family
G0027_RS07395	COG3756	Protein conserved in bacteria
G0027_RS07490	COG0642	Histidine kinase
G0027_RS07495	COG0745	RESPONSE REGULATOR receiver
G0027_RS07500	COG2194	sulfuric ester hydrolase activity
G0027_RS07505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G0027_RS07510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0027_RS07525	COG1570	exodeoxyribonuclease VII activity
G0027_RS07545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G0027_RS07550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G0027_RS07560	COG0659	secondary active sulfate transmembrane transporter activity
G0027_RS07785	COG0583	DNA-binding transcription factor activity
G0027_RS08015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0027_RS08030	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G0027_RS08045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G0027_RS08055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G0027_RS08105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0027_RS08120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G0027_RS08130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G0027_RS08140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G0027_RS08145	COG0438	transferase activity, transferring glycosyl groups
G0027_RS08155	COG0367	asparagine synthase
G0027_RS08205	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G0027_RS08260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_RS08265	COG1309	transcriptional regulator
G0027_RS08275	COG2233	PERMEase
G0027_RS08295	COG0129	dihydroxy-acid dehydratase activity
G0027_RS08305	COG0129	dihydroxy-acid dehydratase activity
G0027_RS08315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G0027_RS08325	COG0733	neurotransmitter:sodium symporter activity
G0027_RS08340	COG1012	belongs to the aldehyde dehydrogenase family
G0027_RS08350	COG2814	Major facilitator Superfamily
G0027_RS08400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G0027_RS08405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G0027_RS08430	COG0488	(ABC) transporter
G0027_RS08435	COG1063	alcohol dehydrogenase
G0027_RS08450	COG0187	DNA topoisomerase II activity
G0027_RS08460	COG0592	DNA-directed DNA polymerase activity
G0027_RS08465	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0027_RS08475	COG0594	ribonuclease P activity
G0027_RS08480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G0027_RS08485	COG0706	membrane insertase activity
G0027_RS08520	COG1230	cation diffusion facilitator family transporter
G0027_RS08525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G0027_RS08545	COG0402	S-adenosylhomocysteine deaminase activity
G0027_RS08550	COG0861	Integral membrane protein TerC family
G0027_RS08560	COG2388	GCN5-related N-acetyl-transferase
G0027_RS08580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0027_RS08600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G0027_RS08610	COG2951	lytic endotransglycosylase activity
G0027_RS08645	COG0657	acetylesterase activity
G0027_RS08655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G0027_RS08685	COG2814	Major facilitator Superfamily
G0027_RS08700	COG1047	Peptidyl-prolyl cis-trans
G0027_RS08705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G0027_RS08710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G0027_RS08715	COG0196	riboflavin kinase activity
G0027_RS08730	COG1309	transcriptional regulator
G0027_RS08740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0027_RS08745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0027_RS08750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G0027_RS08750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G0027_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS08795	COG0546	phosphoglycolate phosphatase activity
G0027_RS08800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G0027_RS08810	COG1309	transcriptional regulator
G0027_RS08815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G0027_RS08825	COG3023	N-Acetylmuramoyl-L-alanine amidase
G0027_RS08845	COG1064	alcohol dehydrogenase
G0027_RS08850	COG2818	Glycosylase
G0027_RS08865	COG1194	a g-specific adenine glycosylase
G0027_RS08880	COG5487	UPF0391 membrane protein
G0027_RS08885	COG2983	Belongs to the UPF0260 family
G0027_RS08890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G0027_RS08895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G0027_RS08905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G0027_RS08910	COG2814	Major facilitator Superfamily
G0027_RS08915	COG1335	isochorismatase
G0027_RS08920	COG0385	Bile acid
G0027_RS08935	COG3830	Belongs to the UPF0237 family
G0027_RS08935	COG0560	Phosphoserine phosphatase
G0027_RS08955	COG0753	catalase activity
G0027_RS09010	COG0534	Mate efflux family protein
G0027_RS09015	COG0436	Aminotransferase
G0027_RS09020	COG2733	membrane
G0027_RS09035	COG2918	glutathione biosynthetic process
G0027_RS09040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G0027_RS09050	COG3150	esterase
G0027_RS09090	COG0471	metal ion transport
G0027_RS09105	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G0027_RS09110	COG4266	Belongs to the allantoicase family
G0027_RS09115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_RS09120	COG1247	-acetyltransferase
G0027_RS09160	COG0625	glutathione transferase activity
G0027_RS09170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G0027_RS09185	COG1393	Belongs to the ArsC family
G0027_RS09190	COG0708	Exodeoxyribonuclease III
G0027_RS09235	COG4115	mRNA cleavage
G0027_RS09245	COG0189	ligase activity
G0027_RS09250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G0027_RS09255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0027_RS09265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G0027_RS09275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G0027_RS09305	COG2119	membrane
G0027_RS09310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0027_RS09310	COG0426	domain, Protein
G0027_RS09335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G0027_RS09355	COG0640	Transcriptional regulator
G0027_RS09360	COG1902	pentaerythritol trinitrate reductase activity
G0027_RS09365	COG1519	Transferase
G0027_RS09370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0027_RS09375	COG0668	transmembrane transport
G0027_RS09380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0027_RS09405	COG0784	Response regulator, receiver
G0027_RS09405	COG2205	protein histidine kinase activity
G0027_RS09410	COG3162	membrane
G0027_RS09415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0027_RS09435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G0027_RS09450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G0027_RS09465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0027_RS09475	COG2814	Major facilitator Superfamily
G0027_RS09480	COG0629	single-stranded DNA binding
G0027_RS09495	COG4372	Transposase
G0027_RS09560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0027_RS09590	COG2132	Multicopper oxidase
G0027_RS09605	COG2801	Transposase and inactivated derivatives
G0027_RS09610	COG3077	Addiction module antitoxin, RelB DinJ family
G0027_RS09640	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G0027_RS09665	COG3158	transport of potassium into the cell
G0027_RS09710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G0027_RS09725	COG0697	spore germination
G0027_RS09745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G0027_RS09775	COG0427	acetyl-CoA hydrolase
G0027_RS09800	COG4221	oxidoreductase activity
G0027_RS09810	COG0488	(ABC) transporter
G0027_RS09840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0027_RS09850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0027_RS09855	COG0275	rRNA processing
G0027_RS09870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G0027_RS09875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G0027_RS09885	COG2226	methyltransferase
G0027_RS09890	COG3385	transposase activity
G0027_RS09950	COG0067	glutamate synthase
G0027_RS09950	COG0069	glutamate synthase activity
G0027_RS09950	COG0070	glutamate synthase
G0027_RS09955	COG0493	'glutamate synthase
G0027_RS09965	COG1704	LemA family
G0027_RS09970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G0027_RS09980	COG2801	Transposase and inactivated derivatives
G0027_RS10005	COG3307	-O-antigen
G0027_RS10025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0027_RS10030	COG1758	RNA polymerase activity
G0027_RS10035	COG0194	GDP metabolic process
G0027_RS10090	COG4969	Belongs to the N-Me-Phe pilin family
G0027_RS10100	COG0228	four-way junction DNA binding
G0027_RS10105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G0027_RS10115	COG0335	large ribosomal subunit rRNA binding
G0027_RS10120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G0027_RS10165	COG5380	lipid catabolic process
G0027_RS10170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G0027_RS10195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0027_RS10200	COG0277	FAD linked oxidase domain protein
G0027_RS10215	COG2814	Major facilitator Superfamily
G0027_RS10225	COG0628	permease
G0027_RS10230	COG1192	Involved in chromosome partitioning
G0027_RS10255	COG2226	methyltransferase
G0027_RS10275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G0027_RS10280	COG0254	rRNA binding
G0027_RS10285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0027_RS10290	COG0534	Mate efflux family protein
G0027_RS10300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0027_RS10305	COG1960	acyl-CoA dehydrogenase activity
G0027_RS10325	COG0408	coproporphyrinogen oxidase activity
G0027_RS10330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0027_RS10355	COG1127	ABC transporter
G0027_RS10360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G0027_RS10365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G0027_RS10370	COG2854	intermembrane phospholipid transfer
G0027_RS10380	COG0598	Magnesium transport protein CorA
G0027_RS10395	COG1040	competence protein
G0027_RS10400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G0027_RS10410	COG2937	Belongs to the GPAT DAPAT family
G0027_RS10415	COG1946	Acyl-CoA thioesterase
G0027_RS10425	COG1301	dicarboxylic acid transport
G0027_RS10445	COG1959	2 iron, 2 sulfur cluster binding
G0027_RS10455	COG0433	COG0433 Predicted ATPase
G0027_RS10480	COG0088	Forms part of the polypeptide exit tunnel
G0027_RS10510	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G0027_RS10545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G0027_RS10550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G0027_RS10560	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G0027_RS10595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G0027_RS10600	COG0202	RNA polymerase activity
G0027_RS10610	COG2072	flavoprotein involved in K transport
G0027_RS10615	COG1960	acyl-CoA dehydrogenase activity
G0027_RS10620	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G0027_RS10645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G0027_RS10650	COG0697	spore germination
G0027_RS10685	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G0027_RS10690	COG0339	signal peptide processing
G0027_RS10695	COG0557	exoribonuclease II activity
G0027_RS10730	COG0179	Fumarylacetoacetate (FAA) hydrolase
G0027_RS10760	COG3040	lipid binding
G0027_RS10825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_RS10825	COG2813	Specifically methylates the guanine in position
G0027_RS10830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_RS10835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G0027_RS10845	COG3128	pkhd-type hydroxylase
G0027_RS10850	COG4774	siderophore transport
G0027_RS10855	COG4771	TonB-dependent receptor
G0027_RS10865	COG0740	serine-type endopeptidase activity
G0027_RS10880	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G0027_RS10880	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G0027_RS10920	COG2801	Transposase and inactivated derivatives
G0027_RS10925	COG0280	phosphate acetyltransferase
G0027_RS10925	COG0857	belongs to the CobB CobQ family
G0027_RS10930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G0027_RS10945	COG0596	Alpha beta hydrolase
G0027_RS10945	COG2226	methyltransferase
G0027_RS10945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_RS10960	COG0793	Belongs to the peptidase S41A family
G0027_RS10990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G0027_RS11005	COG0084	hydrolase, TatD family'
G0027_RS11010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G0027_RS11015	COG3385	transposase activity
G0027_RS11020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G0027_RS11045	COG1785	Belongs to the alkaline phosphatase family
G0027_RS11050	COG1785	Belongs to the alkaline phosphatase family
G0027_RS11140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G0027_RS11150	COG0732	type I restriction modification DNA specificity domain
G0027_RS11160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G0027_RS11180	COG1058	Belongs to the CinA family
G0027_RS11180	COG1546	Belongs to the CinA family
G0027_RS11200	COG2814	Major facilitator Superfamily
G0027_RS11205	COG0697	spore germination
G0027_RS11230	COG3622	Belongs to the hyi family
G0027_RS11240	COG1024	Enoyl-CoA hydratase
G0027_RS11245	COG5002	protein histidine kinase activity
G0027_RS11245	COG0784	Response regulator, receiver
G0027_RS11245	COG2205	protein histidine kinase activity
G0027_RS11250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0027_RS11265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0027_RS11285	COG1862	Preprotein translocase
G0027_RS11300	COG1704	LemA family
G0027_RS11310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G0027_RS11325	COG5002	protein histidine kinase activity
G0027_RS11330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G0027_RS11350	COG0438	transferase activity, transferring glycosyl groups
G0027_RS11400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G0027_RS11430	COG3223	Belongs to the PsiE family
G0027_RS11435	COG1960	acyl-CoA dehydrogenase activity
G0027_RS11440	COG1960	acyl-CoA dehydrogenase activity
G0027_RS11455	COG2205	protein histidine kinase activity
G0027_RS11460	COG0745	RESPONSE REGULATOR receiver
G0027_RS11485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G0027_RS11490	COG3385	transposase activity
G0027_RS11510	COG2096	Adenosyltransferase
G0027_RS11515	COG4206	TonB-dependent receptor
G0027_RS11560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G0027_RS11565	COG0285	dihydrofolate synthase activity
G0027_RS11590	COG0450	alkyl hydroperoxide reductase
G0027_RS11605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G0027_RS11610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G0027_RS11635	COG2885	chlorophyll binding
G0027_RS11700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G0027_RS11705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G0027_RS11725	COG0494	nUDIX hydrolase
G0027_RS11735	COG1214	PFAM Peptidase M22, glycoprotease
G0027_RS11740	COG1968	undecaprenyl-diphosphatase activity
G0027_RS11760	COG4269	membrane
G0027_RS11775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G0027_RS11785	COG2132	Multicopper oxidase
G0027_RS11800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G0027_RS11815	COG0351	phosphomethylpyrimidine kinase
G0027_RS11815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0027_RS11815	COG0352	thiamine-phosphate diphosphorylase activity
G0027_RS11840	COG0251	oxidation-reduction process
G0027_RS11845	COG1113	amino acid transport
G0027_RS11850	COG1981	membrane
G0027_RS11865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G0027_RS11890	COG0456	acetyltransferase
G0027_RS11900	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G0027_RS11905	COG0492	ferredoxin-NADP+ reductase activity
G0027_RS11910	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G0027_RS11910	COG1674	ftsk spoiiie
G0027_RS11925	COG2894	cell division
G0027_RS11930	COG0850	regulation of cytokinetic process
G0027_RS11940	COG0204	Acyl-transferase
G0027_RS11945	COG2885	chlorophyll binding
G0027_RS11950	COG0210	DNA helicase
G0027_RS11960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0027_RS12010	COG2914	Belongs to the UPF0125 (RnfH) family
G0027_RS12015	COG3385	transposase activity
G0027_RS12020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0027_RS12025	COG0735	belongs to the Fur family
G0027_RS12055	COG0420	3'-5' exonuclease activity
G0027_RS12075	COG2050	protein possibly involved in aromatic compounds catabolism
G0027_RS12080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G0027_RS12115	COG1414	Transcriptional regulator
G0027_RS12120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_RS12125	COG1414	Transcriptional regulator
G0027_RS12130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0027_RS12135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_RS12140	COG0183	Belongs to the thiolase family
G0027_RS12145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G0027_RS12150	COG0596	Alpha beta hydrolase
G0027_RS12155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G0027_RS12160	COG3485	protocatechuate 3,4-dioxygenase
G0027_RS12165	COG3485	protocatechuate 3,4-dioxygenase
G0027_RS12195	COG1960	acyl-CoA dehydrogenase activity
G0027_RS12200	COG1022	Amp-dependent synthetase and ligase
G0027_RS12200	COG3320	Male sterility
G0027_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
G0027_RS12210	COG1024	Enoyl-CoA hydratase
G0027_RS12215	COG2814	Major facilitator Superfamily
G0027_RS12230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G0027_RS12250	COG3177	Filamentation induced by cAMP protein fic
G0027_RS12280	COG0726	polysaccharide deacetylase
G0027_RS12280	COG1649	PFAM Uncharacterised BCR, COG1649
G0027_RS12285	COG1215	transferase activity, transferring glycosyl groups
G0027_RS12300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G0027_RS12340	COG3328	transposase activity
G0027_RS12350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0027_RS12355	COG0154	amidase activity
G0027_RS12360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0027_RS12365	COG1077	Cell shape determining protein MreB Mrl
G0027_RS12370	COG1792	Involved in formation and maintenance of cell shape
G0027_RS12375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G0027_RS12380	COG0424	maF-like protein
G0027_RS12385	COG1530	ribonuclease E activity
G0027_RS12395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G0027_RS12435	COG0625	glutathione transferase activity
G0027_RS12445	COG0675	Transposase, IS605 OrfB family
G0027_RS12460	COG1113	amino acid transport
G0027_RS12465	COG2828	Protein conserved in bacteria
G0027_RS12470	COG0142	geranyltranstransferase activity
G0027_RS12480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0027_RS12500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G0027_RS12510	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G0027_RS12515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0027_RS12520	COG0839	Belongs to the complex I subunit 6 family
G0027_RS12525	COG0713	ATP synthesis coupled electron transport
G0027_RS12530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0027_RS12535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0027_RS12550	COG1278	Cold shock
G0027_RS12555	COG1278	Cold shock
G0027_RS12560	COG0583	DNA-binding transcription factor activity
G0027_RS12590	COG0668	transmembrane transport
G0027_RS12605	COG2081	HI0933 family
G0027_RS12640	COG0004	ammonium transporteR
G0027_RS12655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0027_RS12655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0027_RS12660	COG0489	protein tyrosine kinase activity
G0027_RS12675	COG2358	TRAP transporter, solute receptor (TAXI family
G0027_RS12710	COG0442	prolyl-tRNA aminoacylation
G0027_RS12745	COG0840	transmembrane signaling receptor activity
G0027_RS12750	COG2198	Histidine kinase
G0027_RS12750	COG0784	Response regulator, receiver
G0027_RS12750	COG0643	Histidine kinase
G0027_RS12765	COG5510	response to toxic substance
G0027_RS12775	COG2832	Protein of unknown function (DUF454)
G0027_RS12780	COG1376	ErfK ybiS ycfS ynhG family protein
G0027_RS12835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G0027_RS12845	COG1289	transmembrane transporter activity
G0027_RS12850	COG2814	Major facilitator Superfamily
G0027_RS12865	COG0786	glutamate:sodium symporter activity
G0027_RS12870	COG1115	amino acid carrier protein
G0027_RS12875	COG2059	Chromate
G0027_RS12880	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0027_RS12890	COG1607	acyl-coa hydrolase
G0027_RS12900	COG2814	Major facilitator Superfamily
G0027_RS12905	COG0583	DNA-binding transcription factor activity
G0027_RS12935	COG0523	cobalamin synthesis protein
G0027_RS12940	COG4681	YaeQ
G0027_RS12950	COG2203	Gaf domain
G0027_RS12950	COG2199	diguanylate cyclase activity
G0027_RS12980	COG0477	Major facilitator Superfamily
G0027_RS12990	COG2066	Belongs to the glutaminase family
G0027_RS13000	COG0306	phosphate transporter
G0027_RS13040	COG4771	TonB-dependent receptor
G0027_RS13045	COG0500	methyltransferase
G0027_RS13075	COG4181	ATPase activity
G0027_RS13080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G0027_RS13090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0027_RS13100	COG0583	DNA-binding transcription factor activity
G0027_RS13110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_RS13115	COG1773	rubredoxin
G0027_RS13120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G0027_RS13150	COG3118	belongs to the thioredoxin family
G0027_RS13175	COG1253	flavin adenine dinucleotide binding
G0027_RS13195	COG3015	lipoprotein NlpE involved in copper resistance
G0027_RS13210	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS13230	COG0804	urea catabolic process
G0027_RS13235	COG3385	transposase activity
G0027_RS13245	COG3328	transposase activity
G0027_RS13260	COG0830	nickel cation binding
G0027_RS13275	COG0742	ribosomal rna small subunit methyltransferase
G0027_RS13280	COG0768	penicillin binding
G0027_RS13305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G0027_RS13310	COG2878	Part of a membrane complex involved in electron transport
G0027_RS13315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G0027_RS13325	COG3384	dioxygenase
G0027_RS13335	COG2234	aminopeptidase activity
G0027_RS13345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G0027_RS13380	COG2186	Transcriptional regulator
G0027_RS13390	COG0277	FAD linked oxidase domain protein
G0027_RS13420	COG3079	Belongs to the UPF0149 family
G0027_RS13425	COG0006	proline dipeptidase activity
G0027_RS13435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_RS13440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_RS13475	COG2816	NAD+ diphosphatase activity
G0027_RS13490	COG1388	LysM domain
G0027_RS13490	COG0741	lytic transglycosylase activity
G0027_RS13495	COG4166	transmembrane transport
G0027_RS13500	COG4174	ABC transporter (Permease)
G0027_RS13505	COG4239	(ABC) transporter, permease
G0027_RS13510	COG4172	Belongs to the ABC transporter superfamily
G0027_RS13540	COG0833	amino acid
G0027_RS13565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G0027_RS13570	COG0418	dihydroorotase activity
G0027_RS13575	COG2203	Gaf domain
G0027_RS13575	COG3706	GGDEF domain
G0027_RS13575	COG4251	negative regulation of phosphorylation
G0027_RS13575	COG5001	Diguanylate cyclase
G0027_RS13590	COG1902	pentaerythritol trinitrate reductase activity
G0027_RS13590	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0027_RS13630	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G0027_RS13650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0027_RS13655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G0027_RS13660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G0027_RS13685	COG1960	acyl-CoA dehydrogenase activity
G0027_RS13690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G0027_RS13700	COG2175	clavaminate synthase activity
G0027_RS13720	COG0052	Belongs to the universal ribosomal protein uS2 family
G0027_RS13745	COG2951	lytic endotransglycosylase activity
G0027_RS13760	COG0842	Transport permease protein
G0027_RS13765	COG1131	(ABC) transporter
G0027_RS13825	COG3385	transposase activity
G0027_RS13830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0027_RS13850	COG3634	alkyl hydroperoxide reductase activity
G0027_RS13855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0027_RS13860	COG0826	peptidase U32
G0027_RS13870	COG0640	Transcriptional regulator
G0027_RS13880	COG0798	PFAM Bile acid sodium symporter
G0027_RS13885	COG0431	NADPH-dependent FMN reductase
G0027_RS13890	COG0789	Transcriptional regulator
G0027_RS13915	COG1720	tRNA m6t6A37 methyltransferase activity
G0027_RS13925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G0027_RS13960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0027_RS13965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G0027_RS13970	COG3139	Protein of unknown function (DUF1315)
G0027_RS13985	COG1301	dicarboxylic acid transport
G0027_RS13990	COG1960	acyl-CoA dehydrogenase activity
G0027_RS13995	COG0693	protein deglycase activity
G0027_RS14005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G0027_RS14010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G0027_RS14035	COG1047	Peptidyl-prolyl cis-trans
G0027_RS14040	COG1252	NADH dehydrogenase
G0027_RS14045	COG1686	Belongs to the peptidase S11 family
G0027_RS14060	COG1187	pseudouridine synthase activity
G0027_RS14075	COG0739	heme binding
G0027_RS14085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0027_RS14095	COG0612	Peptidase, M16
G0027_RS14105	COG3385	transposase activity
G0027_RS14135	COG0352	thiamine-phosphate diphosphorylase activity
G0027_RS14150	COG2801	Transposase and inactivated derivatives
G0027_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_RS14165	COG2801	Transposase and inactivated derivatives
G0027_RS14195	COG0596	Alpha beta hydrolase
G0027_RS14200	COG1309	transcriptional regulator
G0027_RS14235	COG1278	Cold shock
G0027_RS14255	COG2070	2-Nitropropane dioxygenase
G0027_RS14280	COG2391	methyltransferase activity
G0027_RS14285	COG3385	transposase activity
G0027_RS14295	COG3634	alkyl hydroperoxide reductase activity
G0027_RS14325	COG1643	Atp-dependent helicase
G0027_RS14350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G0027_RS14350	COG0517	IMP dehydrogenase activity
G0027_RS14355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G0027_RS14365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G0027_RS14370	COG1137	ATPase activity
G0027_RS14415	COG4122	O-methyltransferase activity
G0027_RS14425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G0027_RS14440	COG1454	alcohol dehydrogenase
G0027_RS14470	COG2011	ABC-type metal ion transport system permease component
G0027_RS14475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G0027_RS14495	COG0138	bifunctional purine biosynthesis protein purh
G0027_RS14500	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G0027_RS14540	COG2308	Evidence 4 Homologs of previously reported genes of
G0027_RS14550	COG1305	Transglutaminase-like
G0027_RS14565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G0027_RS14580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G0027_RS14585	COG0360	Binds together with S18 to 16S ribosomal RNA
G0027_RS14595	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G0027_RS14600	COG1845	cytochrome c oxidase, subunit III
G0027_RS14605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G0027_RS14610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G0027_RS14635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0027_RS14650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G0027_RS14660	COG3781	membrane
G0027_RS14680	COG1960	acyl-CoA dehydrogenase activity
G0027_RS14700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G0027_RS14710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G0027_RS14725	COG0477	Major facilitator Superfamily
G0027_RS14770	COG0786	glutamate:sodium symporter activity
G0027_RS14805	COG0308	aminopeptidase N
G0027_RS14815	COG0589	response to stress
G0027_RS14820	COG0589	response to stress
G0027_RS14830	COG3135	benzoate transporter
G0027_RS14840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G0027_RS14855	COG0183	Belongs to the thiolase family
G0027_RS14865	COG2030	dehydratase
G0027_RS14870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G0027_RS14880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G0027_RS14885	COG0824	Thioesterase
G0027_RS14890	COG1454	alcohol dehydrogenase
G0027_RS14895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G0027_RS14915	COG0069	glutamate synthase activity
G0027_RS14925	COG4585	Histidine kinase
G0027_RS14930	COG2850	peptidyl-arginine hydroxylation
G0027_RS14935	COG0424	maF-like protein
G0027_RS14960	COG3385	transposase activity
G0027_RS14965	COG0697	spore germination
G0027_RS15005	COG3698	Phosphodiester glycosidase
G0027_RS15025	COG0506	proline dehydrogenase activity
G0027_RS15025	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0027_RS15025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0027_RS15035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0027_RS15040	COG1027	Aspartate ammonia-lyase
G0027_RS15045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G0027_RS15050	COG0583	DNA-binding transcription factor activity
G0027_RS15055	COG1960	acyl-CoA dehydrogenase activity
G0027_RS15060	COG2814	Major facilitator Superfamily
G0027_RS15065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0027_RS15080	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0027_RS15080	COG1902	pentaerythritol trinitrate reductase activity
G0027_RS15115	COG0148	phosphopyruvate hydratase activity
G0027_RS15130	COG0772	Belongs to the SEDS family
G0027_RS15145	COG2137	regulation of response to DNA damage stimulus
G0027_RS15155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G0027_RS15160	COG1011	Hydrolase
G0027_RS15180	COG0268	Binds directly to 16S ribosomal RNA
G0027_RS15185	COG0702	epimerase
G0027_RS15190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G0027_RS15205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G0027_RS15235	COG0316	Belongs to the HesB IscA family
G0027_RS15240	COG0822	iron-sulfur transferase activity
G0027_RS15270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0027_RS15325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G0027_RS15345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0027_RS15355	COG0133	tryptophan synthase activity
G0027_RS15360	COG0617	tRNA 3'-terminal CCA addition
G0027_RS15360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0027_RS15360	COG0517	IMP dehydrogenase activity
G0027_RS15390	COG0612	Peptidase, M16
G0027_RS15395	COG0552	protein localization to endoplasmic reticulum
G0027_RS15440	COG0693	protein deglycase activity
G0027_RS15450	COG1283	sodium-dependent phosphate transmembrane transporter activity
G0027_RS15460	COG1346	cytolysis
G0027_RS15470	COG0583	DNA-binding transcription factor activity
G0027_RS15490	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G0027_RS15495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0027_RS15510	COG1629	transport
G0027_RS15520	COG1960	acyl-CoA dehydrogenase activity
G0027_RS15525	COG2207	Transcriptional regulator
G0027_RS15525	COG1917	Cupin 2, conserved barrel domain protein
G0027_RS15530	COG2814	Major facilitator Superfamily
G0027_RS15540	COG1271	oxidase subunit
G0027_RS15555	COG1525	nuclease
G0027_RS15610	COG1192	Involved in chromosome partitioning
G0027_RS15690	COG0745	RESPONSE REGULATOR receiver
G0027_RS15695	COG0642	Histidine kinase
G0027_RS15760	COG0582	viral genome integration into host DNA
G0027_RS15765	COG0789	Transcriptional regulator
G0027_RS15775	COG1230	cation diffusion facilitator family transporter
G0027_RS15795	COG4372	Transposase
G0027_RS15800	COG3657	addiction module killer protein
G0027_RS15805	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_RS15810	COG2801	Transposase and inactivated derivatives
G0027_RS15820	COG2801	Transposase and inactivated derivatives
G0027_RS15835	COG2801	Transposase and inactivated derivatives
G0027_RS15840	COG0488	(ABC) transporter
G0027_RS15845	COG3173	Aminoglycoside phosphotransferase
G0027_RS15905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0027_RS15915	COG5002	protein histidine kinase activity
G0027_RS15925	COG2801	Transposase and inactivated derivatives
G0027_RS15955	COG1660	Displays ATPase and GTPase activities
G0027_RS16000	COG2801	Transposase and inactivated derivatives
G0027_RS16055	COG2963	transposase activity
G0027_RS16080	COG2801	Transposase and inactivated derivatives
G0027_RS16095	COG2801	Transposase and inactivated derivatives
G0027_RS16150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0027_RS16225	COG1373	ATPase (AAA superfamily
G0027_RS16260	COG1475	DNA binding
G0027_RS16265	COG1192	Involved in chromosome partitioning
G0027_RS16300	COG2801	Transposase and inactivated derivatives
G0027_RS16305	COG2801	Transposase and inactivated derivatives
G0027_RS16320	COG2801	Transposase and inactivated derivatives
G0027_RS16335	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
G0027_RS16410	COG3188	usher protein
G0027_RS16430	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_RS16435	COG3657	addiction module killer protein
G0027_RS16440	COG2801	Transposase and inactivated derivatives
G0027_RS16485	COG3188	usher protein
G0027_RS16505	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_RS16510	COG3657	addiction module killer protein
G0027_RS16515	COG2801	Transposase and inactivated derivatives
G0027_RS16555	COG2076	Multidrug Resistance protein
G0027_RS16570	COG0488	(ABC) transporter