locus-tag	class	description
FSC02_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC02_RS00010	COG0592	DNA-directed DNA polymerase activity
FSC02_RS00020	COG0187	DNA topoisomerase II activity
FSC02_RS00035	COG1063	alcohol dehydrogenase
FSC02_RS00040	COG0488	(ABC) transporter
FSC02_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FSC02_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSC02_RS00120	COG2814	Major facilitator Superfamily
FSC02_RS00130	COG1012	belongs to the aldehyde dehydrogenase family
FSC02_RS00135	COG0733	neurotransmitter:sodium symporter activity
FSC02_RS00145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSC02_RS00160	COG0129	dihydroxy-acid dehydratase activity
FSC02_RS00175	COG2233	PERMEase
FSC02_RS00185	COG1309	transcriptional regulator
FSC02_RS00190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC02_RS00245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FSC02_RS00255	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSC02_RS00285	COG0463	Glycosyl transferase, family 2
FSC02_RS00285	COG1216	Glycosyl transferase, family 2
FSC02_RS00290	COG0438	transferase activity, transferring glycosyl groups
FSC02_RS00300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC02_RS00305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FSC02_RS00315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSC02_RS00320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSC02_RS00330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSC02_RS00345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC02_RS00395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSC02_RS00405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FSC02_RS00420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FSC02_RS00440	COG0583	DNA-binding transcription factor activity
FSC02_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS00450	COG2271	Major facilitator Superfamily
FSC02_RS00455	COG3959	Transketolase, thiamine diphosphate binding domain
FSC02_RS00460	COG3958	Transketolase
FSC02_RS00525	COG2801	Transposase and inactivated derivatives
FSC02_RS00535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSC02_RS00540	COG1335	isochorismatase
FSC02_RS00625	COG3756	Protein conserved in bacteria
FSC02_RS00660	COG0271	Belongs to the BolA IbaG family
FSC02_RS00670	COG1192	Involved in chromosome partitioning
FSC02_RS00685	COG0586	Pfam SNARE associated Golgi protein
FSC02_RS00690	COG2259	Doxx family
FSC02_RS00695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC02_RS00695	COG0519	Catalyzes the synthesis of GMP from XMP
FSC02_RS00700	COG1715	Restriction endonuclease
FSC02_RS00740	COG0281	malic enzyme
FSC02_RS00745	COG3501	Rhs element vgr protein
FSC02_RS00790	COG2837	iron assimilation
FSC02_RS00800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSC02_RS00805	COG1121	(ABC) transporter
FSC02_RS00855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSC02_RS00880	COG0386	Belongs to the glutathione peroxidase family
FSC02_RS00885	COG0697	spore germination
FSC02_RS00900	COG0758	DNA mediated transformation
FSC02_RS00950	COG2814	Major facilitator Superfamily
FSC02_RS00970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC02_RS00985	COG2814	Major facilitator Superfamily
FSC02_RS01005	COG1253	flavin adenine dinucleotide binding
FSC02_RS01015	COG2860	membrane
FSC02_RS01020	COG0477	Major facilitator Superfamily
FSC02_RS01030	COG0318	PFAM AMP-dependent synthetase and ligase
FSC02_RS01045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSC02_RS01070	COG0347	Belongs to the P(II) protein family
FSC02_RS01075	COG0004	ammonium transporteR
FSC02_RS01085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC02_RS01085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC02_RS01100	COG0586	Pfam SNARE associated Golgi protein
FSC02_RS01125	COG0795	lipopolysaccharide-transporting ATPase activity
FSC02_RS01130	COG0795	lipopolysaccharide-transporting ATPase activity
FSC02_RS01135	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSC02_RS01140	COG0793	Belongs to the peptidase S41A family
FSC02_RS01155	COG2197	response regulator
FSC02_RS01165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSC02_RS01180	COG4974	Belongs to the 'phage' integrase family
FSC02_RS01205	COG0772	Belongs to the SEDS family
FSC02_RS01215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC02_RS01220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSC02_RS01225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSC02_RS01290	COG3275	phosphorelay sensor kinase activity
FSC02_RS01300	COG0181	hydroxymethylbilane synthase activity
FSC02_RS01320	COG0824	Thioesterase
FSC02_RS01405	COG0081	regulation of translation
FSC02_RS01420	COG0085	RNA polymerase activity
FSC02_RS01425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSC02_RS01445	COG2056	Na+-H+ antiporter family
FSC02_RS01460	COG0326	Molecular chaperone. Has ATPase activity
FSC02_RS01465	COG3385	transposase activity
FSC02_RS01490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSC02_RS01500	COG2233	PERMEase
FSC02_RS01510	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC02_RS01510	COG1024	Enoyl-CoA hydratase
FSC02_RS01530	COG0322	excinuclease ABC activity
FSC02_RS01540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSC02_RS01545	COG3385	transposase activity
FSC02_RS01550	COG1132	(ABC) transporter
FSC02_RS01565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSC02_RS01575	COG0497	DNA recombination
FSC02_RS01580	COG3123	guanosine phosphorylase activity
FSC02_RS01585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC02_RS01595	COG0237	dephospho-CoA kinase activity
FSC02_RS01645	COG0779	Required for maturation of 30S ribosomal subunits
FSC02_RS01650	COG0195	Participates in both transcription termination and antitermination
FSC02_RS01660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSC02_RS01670	COG2212	antiporter activity
FSC02_RS01680	COG0651	ATP synthesis coupled electron transport
FSC02_RS01685	COG1006	Multisubunit Na H antiporter MnhC subunit
FSC02_RS01690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC02_RS01690	COG2111	Na H antiporter
FSC02_RS01705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSC02_RS01715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC02_RS01745	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSC02_RS01750	COG1074	ATP-dependent DNA helicase activity
FSC02_RS01755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC02_RS01760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSC02_RS01775	COG2841	Protein conserved in bacteria
FSC02_RS01780	COG0789	Transcriptional regulator
FSC02_RS01790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSC02_RS01800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSC02_RS01820	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSC02_RS01825	COG4535	Mg2 and Co2 transporter CorC
FSC02_RS01830	COG0425	Belongs to the sulfur carrier protein TusA family
FSC02_RS01835	COG3501	Rhs element vgr protein
FSC02_RS01865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSC02_RS01865	COG0644	oxidoreductase
FSC02_RS01875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSC02_RS01890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC02_RS01900	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FSC02_RS01910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC02_RS01910	COG0493	'glutamate synthase
FSC02_RS01920	COG2226	methyltransferase
FSC02_RS01935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC02_RS01965	COG0751	glycine-tRNA ligase activity
FSC02_RS01975	COG0517	IMP dehydrogenase activity
FSC02_RS01975	COG0617	tRNA 3'-terminal CCA addition
FSC02_RS01975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSC02_RS01980	COG1983	PspC domain protein
FSC02_RS02005	COG0318	PFAM AMP-dependent synthetase and ligase
FSC02_RS02010	COG1530	ribonuclease E activity
FSC02_RS02020	COG0546	phosphoglycolate phosphatase activity
FSC02_RS02025	COG3971	2-oxopent-4-enoate hydratase activity
FSC02_RS02030	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSC02_RS02055	COG0583	DNA-binding transcription factor activity
FSC02_RS02060	COG4638	Rieske (2fe-2S)
FSC02_RS02075	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS02080	COG3384	dioxygenase
FSC02_RS02085	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC02_RS02100	COG0753	catalase activity
FSC02_RS02110	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS02130	COG0494	nUDIX hydrolase
FSC02_RS02145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSC02_RS02160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSC02_RS02175	COG0473	3-isopropylmalate dehydrogenase activity
FSC02_RS02230	COG1560	Kdo2-lipid A biosynthetic process
FSC02_RS02240	COG2900	Belongs to the SlyX family
FSC02_RS02270	COG1929	Belongs to the glycerate kinase type-1 family
FSC02_RS02280	COG0210	DNA helicase
FSC02_RS02285	COG0724	RNA recognition motif
FSC02_RS02300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSC02_RS02300	COG4651	solute:proton antiporter activity
FSC02_RS02325	COG0788	formyltetrahydrofolate deformylase activity
FSC02_RS02355	COG1295	ribonuclease BN
FSC02_RS02400	COG1702	phosphate starvation-inducible protein PhoH
FSC02_RS02410	COG1196	nuclear chromosome segregation
FSC02_RS02410	COG0741	lytic transglycosylase activity
FSC02_RS02410	COG0739	heme binding
FSC02_RS02450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FSC02_RS02455	COG1183	phosphatidylcholine synthase activity
FSC02_RS02520	COG1607	acyl-coa hydrolase
FSC02_RS02530	COG1666	GTP binding
FSC02_RS02550	COG2350	Protein conserved in bacteria
FSC02_RS02560	COG0613	PHP domain protein
FSC02_RS02565	COG3781	membrane
FSC02_RS02575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSC02_RS02585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FSC02_RS02595	COG1162	GTPase activity
FSC02_RS02600	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSC02_RS02615	COG3501	Rhs element vgr protein
FSC02_RS02625	COG1388	LysM domain
FSC02_RS02625	COG3942	CHAP domain
FSC02_RS02650	COG1538	Outer membrane efflux protein
FSC02_RS02655	COG0577	efflux transmembrane transporter activity
FSC02_RS02655	COG1136	(ABC) transporter
FSC02_RS02660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC02_RS02685	COG0028	Belongs to the TPP enzyme family
FSC02_RS02690	COG0440	acetolactate synthase activity
FSC02_RS02730	COG2975	iron-sulfur cluster assembly
FSC02_RS02760	COG0124	histidyl-tRNA synthetase
FSC02_RS02770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC02_RS02785	COG3956	TIGRFAM MazG family protein
FSC02_RS02790	COG1555	photosystem II stabilization
FSC02_RS02795	COG0617	tRNA 3'-terminal CCA addition
FSC02_RS02800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSC02_RS02815	COG1660	Displays ATPase and GTPase activities
FSC02_RS02825	COG3028	Belongs to the UPF0307 family
FSC02_RS02830	COG0318	PFAM AMP-dependent synthetase and ligase
FSC02_RS02845	COG0625	glutathione transferase activity
FSC02_RS02850	COG1238	metal cluster binding
FSC02_RS02885	COG0072	phenylalanine-tRNA ligase activity
FSC02_RS02910	COG0248	Ppx GppA phosphatase
FSC02_RS02920	COG0037	tRNA processing
FSC02_RS02965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC02_RS03020	COG2969	positive regulation of protein catabolic process
FSC02_RS03025	COG0625	glutathione transferase activity
FSC02_RS03030	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSC02_RS03040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FSC02_RS03045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC02_RS03050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC02_RS03080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSC02_RS03090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC02_RS03095	COG1408	metallophosphoesterase
FSC02_RS03105	COG0477	Major facilitator Superfamily
FSC02_RS03110	COG1272	protein, Hemolysin III
FSC02_RS03135	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC02_RS03135	COG1024	Enoyl-CoA hydratase
FSC02_RS03140	COG0183	Belongs to the thiolase family
FSC02_RS03145	COG2207	Transcriptional regulator
FSC02_RS03155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC02_RS03170	COG0183	Belongs to the thiolase family
FSC02_RS03190	COG0833	amino acid
FSC02_RS03200	COG2233	PERMEase
FSC02_RS03210	COG1970	mechanosensitive ion channel activity
FSC02_RS03215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC02_RS03225	COG1877	trehalose-phosphatase activity
FSC02_RS03230	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FSC02_RS03240	COG0363	glucosamine-6-phosphate deaminase activity
FSC02_RS03270	COG0354	folic acid binding
FSC02_RS03300	COG0346	lactoylglutathione lyase activity
FSC02_RS03305	COG0564	pseudouridine synthase activity
FSC02_RS03320	COG3189	MarR family transcriptional regulator
FSC02_RS03325	COG2824	Alkylphosphonate utilization operon protein PhnA
FSC02_RS03335	COG0628	permease
FSC02_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS03365	COG3077	Addiction module antitoxin, RelB DinJ family
FSC02_RS03400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSC02_RS03420	COG0730	response to heat
FSC02_RS03430	COG1196	nuclear chromosome segregation
FSC02_RS03435	COG3115	cell septum assembly
FSC02_RS03440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSC02_RS03445	COG2193	ferroxidase activity
FSC02_RS03450	COG0596	Alpha beta hydrolase
FSC02_RS03450	COG2226	methyltransferase
FSC02_RS03450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC02_RS03465	COG4106	trans-aconitate 2-methyltransferase activity
FSC02_RS03480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSC02_RS03485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSC02_RS03495	COG0009	L-threonylcarbamoyladenylate synthase
FSC02_RS03500	COG3101	peptidyl-lysine hydroxylation
FSC02_RS03505	COG1399	metal-binding, possibly nucleic acid-binding protein
FSC02_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS03530	COG1652	LysM domain
FSC02_RS03535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC02_RS03550	COG0745	RESPONSE REGULATOR receiver
FSC02_RS03555	COG2205	protein histidine kinase activity
FSC02_RS03560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC02_RS03575	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC02_RS03590	COG3338	carbonate dehydratase activity
FSC02_RS03595	COG1126	abc transporter atp-binding protein
FSC02_RS03600	COG0765	amino acid transport
FSC02_RS03605	COG0765	amino acid transport
FSC02_RS03615	COG2323	membrane
FSC02_RS03635	COG3328	transposase activity
FSC02_RS03650	COG0525	valine-tRNA ligase activity
FSC02_RS03665	COG0393	Putative heavy-metal-binding
FSC02_RS03670	COG0393	Putative heavy-metal-binding
FSC02_RS03680	COG1538	Outer membrane efflux protein
FSC02_RS03690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC02_RS03695	COG0671	phosphoesterase, PA-phosphatase related
FSC02_RS03720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FSC02_RS03730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSC02_RS03735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSC02_RS03735	COG1648	precorrin-2 dehydrogenase activity
FSC02_RS03740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FSC02_RS03745	COG0531	amino acid
FSC02_RS03760	COG0321	lipoyl(octanoyl) transferase activity
FSC02_RS03770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSC02_RS03795	COG0586	Pfam SNARE associated Golgi protein
FSC02_RS03835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSC02_RS03865	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FSC02_RS03880	COG0358	DNA primase activity
FSC02_RS03890	COG0564	pseudouridine synthase activity
FSC02_RS03905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSC02_RS03915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC02_RS03945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC02_RS03945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSC02_RS03960	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FSC02_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS03975	COG2072	flavoprotein involved in K transport
FSC02_RS03990	COG2072	flavoprotein involved in K transport
FSC02_RS04005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FSC02_RS04010	COG1053	succinate dehydrogenase
FSC02_RS04015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSC02_RS04030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC02_RS04040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSC02_RS04050	COG1649	PFAM Uncharacterised BCR, COG1649
FSC02_RS04050	COG0726	polysaccharide deacetylase
FSC02_RS04055	COG1215	transferase activity, transferring glycosyl groups
FSC02_RS04065	COG2268	Band 7 protein
FSC02_RS04080	COG2354	Protein conserved in bacteria
FSC02_RS04085	COG2321	neutral zinc metallopeptidase
FSC02_RS04095	COG0589	response to stress
FSC02_RS04100	COG0110	maltose O-acetyltransferase activity
FSC02_RS04105	COG0415	Belongs to the DNA photolyase family
FSC02_RS04110	COG4372	Transposase
FSC02_RS04120	COG2963	transposase activity
FSC02_RS04135	COG0505	Belongs to the CarA family
FSC02_RS04150	COG1534	Rna-binding protein
FSC02_RS04160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC02_RS04170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSC02_RS04205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSC02_RS04225	COG1597	lipid kinase activity
FSC02_RS04260	COG2239	Acts as a magnesium transporter
FSC02_RS04270	COG0501	Belongs to the peptidase M48B family
FSC02_RS04275	COG0739	heme binding
FSC02_RS04275	COG0741	lytic transglycosylase activity
FSC02_RS04275	COG1196	nuclear chromosome segregation
FSC02_RS04280	COG0037	tRNA processing
FSC02_RS04290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FSC02_RS04295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC02_RS04315	COG1840	ABC-type Fe3 transport system, periplasmic component
FSC02_RS04320	COG3842	ATPase activity
FSC02_RS04325	COG1741	Belongs to the pirin family
FSC02_RS04330	COG3385	transposase activity
FSC02_RS04340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FSC02_RS04345	COG3739	integral membrane protein
FSC02_RS04360	COG3706	GGDEF domain
FSC02_RS04390	COG0512	Glutamine amidotransferase of anthranilate synthase
FSC02_RS04395	COG0174	glutamine synthetase
FSC02_RS04405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FSC02_RS04415	COG0583	DNA-binding transcription factor activity
FSC02_RS04450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSC02_RS04455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FSC02_RS04475	COG1115	amino acid carrier protein
FSC02_RS04480	COG1113	amino acid transport
FSC02_RS04490	COG0019	diaminopimelate decarboxylase activity
FSC02_RS04505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSC02_RS04515	COG1522	sequence-specific DNA binding
FSC02_RS04520	COG1280	lysine exporter protein (LysE YggA)
FSC02_RS04560	COG1671	Belongs to the UPF0178 family
FSC02_RS04575	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC02_RS04580	COG1136	(ABC) transporter
FSC02_RS04585	COG0658	competence protein
FSC02_RS04585	COG2333	competence protein COMEC
FSC02_RS04605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSC02_RS04610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSC02_RS04615	COG0628	permease
FSC02_RS04620	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC02_RS04650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC02_RS04670	COG0823	Involved in the tonB-independent uptake of proteins
FSC02_RS04690	COG0824	Thioesterase
FSC02_RS04700	COG2255	four-way junction helicase activity
FSC02_RS04730	COG1358	cellular component organization or biogenesis
FSC02_RS04760	COG2310	stress, protein
FSC02_RS04780	COG0047	phosphoribosylformylglycinamidine synthase activity
FSC02_RS04780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSC02_RS04785	COG3385	transposase activity
FSC02_RS04800	COG0778	Nitroreductase
FSC02_RS04805	COG1024	Enoyl-CoA hydratase
FSC02_RS04810	COG1051	belongs to the nudix hydrolase family
FSC02_RS04810	COG1056	cytidyltransferase-related domain
FSC02_RS04815	COG2353	YceI-like domain
FSC02_RS04820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSC02_RS04830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSC02_RS04835	COG0602	queuosine metabolic process
FSC02_RS04855	COG0583	DNA-binding transcription factor activity
FSC02_RS04860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSC02_RS04865	COG4208	sulfate ABC transporter
FSC02_RS04880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC02_RS04890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSC02_RS04905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC02_RS04915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC02_RS04930	COG0681	Belongs to the peptidase S26 family
FSC02_RS04940	COG0571	ribonuclease III activity
FSC02_RS04945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSC02_RS04955	COG1381	Involved in DNA repair and RecF pathway recombination
FSC02_RS04960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSC02_RS04985	COG0436	Aminotransferase
FSC02_RS05005	COG0556	nucleotide-excision repair
FSC02_RS05045	COG0702	epimerase
FSC02_RS05050	COG1733	regulation of RNA biosynthetic process
FSC02_RS05055	COG2814	Major facilitator Superfamily
FSC02_RS05065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSC02_RS05070	COG0582	viral genome integration into host DNA
FSC02_RS05140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSC02_RS05145	COG0076	glutamate decarboxylase activity
FSC02_RS05160	COG0573	inorganic phosphate transmembrane transporter activity
FSC02_RS05170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSC02_RS05175	COG0616	signal peptide processing
FSC02_RS05180	COG3385	transposase activity
FSC02_RS05215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSC02_RS05220	COG1686	Belongs to the peptidase S11 family
FSC02_RS05235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FSC02_RS05245	COG0583	DNA-binding transcription factor activity
FSC02_RS05250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSC02_RS05255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FSC02_RS05260	COG1067	ATP-dependent peptidase activity
FSC02_RS05295	COG1509	lysine 2,3-aminomutase activity
FSC02_RS05300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSC02_RS05305	COG1966	Carbon starvation protein
FSC02_RS05310	COG2879	small protein
FSC02_RS05315	COG0714	Associated with various cellular activities
FSC02_RS05410	COG2252	PERMEase
FSC02_RS05415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSC02_RS05425	COG1215	transferase activity, transferring glycosyl groups
FSC02_RS05435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSC02_RS05445	COG0527	aspartate kinase activity
FSC02_RS05455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSC02_RS05470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSC02_RS05475	COG0501	Belongs to the peptidase M48B family
FSC02_RS05490	COG0667	Aldo Keto reductase
FSC02_RS05500	COG1765	OsmC-like protein
FSC02_RS05505	COG3385	transposase activity
FSC02_RS05525	COG0540	Belongs to the ATCase OTCase family
FSC02_RS05540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC02_RS05555	COG4770	biotin carboxylase activity
FSC02_RS05560	COG1024	Enoyl-CoA hydratase
FSC02_RS05565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSC02_RS05570	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS05575	COG1309	transcriptional regulator
FSC02_RS05580	COG0318	PFAM AMP-dependent synthetase and ligase
FSC02_RS05600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSC02_RS05610	COG0659	secondary active sulfate transmembrane transporter activity
FSC02_RS05630	COG2363	Small membrane protein
FSC02_RS05650	COG0513	Belongs to the DEAD box helicase family
FSC02_RS05715	COG4783	chaperone-mediated protein folding
FSC02_RS05730	COG1610	YqeY-like protein
FSC02_RS05760	COG2815	serine threonine protein kinase
FSC02_RS05760	COG0515	serine threonine protein kinase
FSC02_RS05800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC02_RS05800	COG2755	lipolytic protein G-D-S-L family
FSC02_RS05805	COG0436	Aminotransferase
FSC02_RS05810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSC02_RS05815	COG0386	Belongs to the glutathione peroxidase family
FSC02_RS05825	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSC02_RS05830	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FSC02_RS05840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FSC02_RS05850	COG0012	GTP binding
FSC02_RS05875	COG0204	Acyl-transferase
FSC02_RS05905	COG1484	DNA-dependent DNA replication
FSC02_RS06010	COG1012	belongs to the aldehyde dehydrogenase family
FSC02_RS06015	COG0129	dihydroxy-acid dehydratase activity
FSC02_RS06025	COG0583	DNA-binding transcription factor activity
FSC02_RS06035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSC02_RS06045	COG2084	Dehydrogenase
FSC02_RS06050	COG2814	Major facilitator Superfamily
FSC02_RS06055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC02_RS06060	COG2186	Transcriptional regulator
FSC02_RS06080	COG1012	belongs to the aldehyde dehydrogenase family
FSC02_RS06100	COG3328	transposase activity
FSC02_RS06105	COG0582	viral genome integration into host DNA
FSC02_RS06220	COG4372	Transposase
FSC02_RS06230	COG2963	transposase activity
FSC02_RS06260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC02_RS06265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSC02_RS06270	COG0022	dehydrogenase e1 component
FSC02_RS06275	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSC02_RS06280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC02_RS06290	COG1063	alcohol dehydrogenase
FSC02_RS06300	COG3328	transposase activity
FSC02_RS06325	COG0183	Belongs to the thiolase family
FSC02_RS06330	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FSC02_RS06335	COG3327	negative regulation of DNA-templated transcription, initiation
FSC02_RS06345	COG0318	PFAM AMP-dependent synthetase and ligase
FSC02_RS06365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FSC02_RS06370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSC02_RS06370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSC02_RS06375	COG1254	Belongs to the acylphosphatase family
FSC02_RS06415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSC02_RS06420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSC02_RS06430	COG2353	YceI-like domain
FSC02_RS06435	COG0519	Catalyzes the synthesis of GMP from XMP
FSC02_RS06435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC02_RS06465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC02_RS06470	COG0583	DNA-binding transcription factor activity
FSC02_RS06480	COG2707	UPF0756 membrane protein
FSC02_RS06505	COG0802	atpase or kinase
FSC02_RS06510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSC02_RS06520	COG1923	regulation of RNA biosynthetic process
FSC02_RS06525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC02_RS06535	COG3178	'Phosphotransferase
FSC02_RS06540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSC02_RS06550	COG1192	Involved in chromosome partitioning
FSC02_RS06555	COG1475	DNA binding
FSC02_RS06560	COG0811	peptide transport
FSC02_RS06570	COG1132	(ABC) transporter
FSC02_RS06575	COG1663	tetraacyldisaccharide 4'-kinase activity
FSC02_RS06595	COG0084	hydrolase, TatD family'
FSC02_RS06630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSC02_RS06660	COG0776	regulation of translation
FSC02_RS06670	COG0284	orotidine-5'-phosphate decarboxylase activity
FSC02_RS06675	COG2431	L-lysine efflux transmembrane transporter activity
FSC02_RS06690	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSC02_RS06695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FSC02_RS06715	COG1253	flavin adenine dinucleotide binding
FSC02_RS06745	COG0583	DNA-binding transcription factor activity
FSC02_RS06760	COG3852	Histidine kinase
FSC02_RS06775	COG0233	cytoplasmic translational termination
FSC02_RS06780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSC02_RS06785	COG0575	Belongs to the CDS family
FSC02_RS06800	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC02_RS06820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC02_RS06850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC02_RS06855	COG0730	response to heat
FSC02_RS06860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC02_RS06865	COG2207	Transcriptional regulator
FSC02_RS06870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC02_RS06880	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS06885	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS06915	COG2963	transposase activity
FSC02_RS06925	COG4372	Transposase
FSC02_RS06935	COG4890	Cyd operon protein YbgT
FSC02_RS06940	COG1294	oxidase, subunit
FSC02_RS06955	COG1585	Membrane protein implicated in regulation of membrane protease activity
FSC02_RS06965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSC02_RS06985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSC02_RS06990	COG0569	domain protein
FSC02_RS07000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSC02_RS07020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSC02_RS07025	COG0542	response to heat
FSC02_RS07060	COG0372	Belongs to the citrate synthase family
FSC02_RS07070	COG1546	Belongs to the CinA family
FSC02_RS07070	COG1058	Belongs to the CinA family
FSC02_RS07105	COG2814	Major facilitator Superfamily
FSC02_RS07120	COG0439	Biotin carboxylase
FSC02_RS07125	COG0511	ligase activity, forming carbon-carbon bonds
FSC02_RS07160	COG0596	Alpha beta hydrolase
FSC02_RS07250	COG2801	Transposase and inactivated derivatives
FSC02_RS07270	COG0730	response to heat
FSC02_RS07275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC02_RS07280	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSC02_RS07290	COG2885	chlorophyll binding
FSC02_RS07310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSC02_RS07320	COG0745	RESPONSE REGULATOR receiver
FSC02_RS07340	COG1012	belongs to the aldehyde dehydrogenase family
FSC02_RS07345	COG1309	transcriptional regulator
FSC02_RS07350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC02_RS07385	COG2963	transposase activity
FSC02_RS07395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC02_RS07410	COG0515	serine threonine protein kinase
FSC02_RS07415	COG2116	formate transmembrane transporter activity
FSC02_RS07420	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FSC02_RS07430	COG2223	nitrite transmembrane transporter activity
FSC02_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS07470	COG2814	Major facilitator Superfamily
FSC02_RS07475	COG0583	DNA-binding transcription factor activity
FSC02_RS07480	COG4948	Mandelate Racemase Muconate Lactonizing
FSC02_RS07485	COG4829	muconolactone delta-isomerase
FSC02_RS07495	COG4638	Rieske (2fe-2S)
FSC02_RS07500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FSC02_RS07505	COG0543	2 iron, 2 sulfur cluster binding
FSC02_RS07505	COG0633	Ferredoxin
FSC02_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS07515	COG3135	benzoate transporter
FSC02_RS07520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC02_RS07525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC02_RS07530	COG0183	Belongs to the thiolase family
FSC02_RS07535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC02_RS07555	COG0583	DNA-binding transcription factor activity
FSC02_RS07560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FSC02_RS07565	COG4149	molybdate abc transporter
FSC02_RS07570	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSC02_RS07575	COG0303	'Molybdopterin
FSC02_RS07580	COG0315	cyclic pyranopterin monophosphate synthase activity
FSC02_RS07580	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSC02_RS07595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSC02_RS07605	COG0243	molybdopterin cofactor binding
FSC02_RS07610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC02_RS07615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC02_RS07620	COG2223	nitrite transmembrane transporter activity
FSC02_RS07630	COG1116	anion transmembrane transporter activity
FSC02_RS07630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC02_RS07635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC02_RS07640	COG2937	Belongs to the GPAT DAPAT family
FSC02_RS07645	COG0640	Transcriptional regulator
FSC02_RS07665	COG3122	Protein conserved in bacteria
FSC02_RS07670	COG0668	transmembrane transport
FSC02_RS07680	COG1132	(ABC) transporter
FSC02_RS07700	COG2814	Major facilitator Superfamily
FSC02_RS07710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC02_RS07720	COG1113	amino acid transport
FSC02_RS07735	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSC02_RS07740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC02_RS07790	COG1525	nuclease
FSC02_RS07800	COG1294	oxidase, subunit
FSC02_RS07805	COG1271	oxidase subunit
FSC02_RS07815	COG2814	Major facilitator Superfamily
FSC02_RS07820	COG2207	Transcriptional regulator
FSC02_RS07825	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS07835	COG1629	transport
FSC02_RS07850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC02_RS07860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC02_RS07985	COG4372	Transposase
FSC02_RS07995	COG2963	transposase activity
FSC02_RS08000	COG2369	cell adhesion
FSC02_RS08005	COG3567	Phage-associated protein, HI1409 family
FSC02_RS08010	COG5410	chromosome segregation
FSC02_RS08070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC02_RS08090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC02_RS08165	COG0582	viral genome integration into host DNA
FSC02_RS08170	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FSC02_RS08190	COG0583	DNA-binding transcription factor activity
FSC02_RS08200	COG1346	cytolysis
FSC02_RS08210	COG1283	sodium-dependent phosphate transmembrane transporter activity
FSC02_RS08220	COG0693	protein deglycase activity
FSC02_RS08265	COG0552	protein localization to endoplasmic reticulum
FSC02_RS08270	COG0612	Peptidase, M16
FSC02_RS08300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSC02_RS08300	COG0617	tRNA 3'-terminal CCA addition
FSC02_RS08300	COG0517	IMP dehydrogenase activity
FSC02_RS08305	COG0133	tryptophan synthase activity
FSC02_RS08315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC02_RS08335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSC02_RS08390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC02_RS08420	COG0822	iron-sulfur transferase activity
FSC02_RS08425	COG0316	Belongs to the HesB IscA family
FSC02_RS08455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSC02_RS08470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC02_RS08475	COG0702	epimerase
FSC02_RS08480	COG0268	Binds directly to 16S ribosomal RNA
FSC02_RS08500	COG1011	Hydrolase
FSC02_RS08505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSC02_RS08515	COG2137	regulation of response to DNA damage stimulus
FSC02_RS08530	COG0772	Belongs to the SEDS family
FSC02_RS08545	COG0148	phosphopyruvate hydratase activity
FSC02_RS08575	COG1902	pentaerythritol trinitrate reductase activity
FSC02_RS08575	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC02_RS08590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSC02_RS08595	COG2814	Major facilitator Superfamily
FSC02_RS08600	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS08605	COG0583	DNA-binding transcription factor activity
FSC02_RS08610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSC02_RS08615	COG1027	Aspartate ammonia-lyase
FSC02_RS08630	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC02_RS08630	COG0506	proline dehydrogenase activity
FSC02_RS08630	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC02_RS08650	COG3698	Phosphodiester glycosidase
FSC02_RS08690	COG0697	spore germination
FSC02_RS08715	COG0424	maF-like protein
FSC02_RS08720	COG2850	peptidyl-arginine hydroxylation
FSC02_RS08725	COG4585	Histidine kinase
FSC02_RS08735	COG0069	glutamate synthase activity
FSC02_RS08760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSC02_RS08765	COG1454	alcohol dehydrogenase
FSC02_RS08770	COG0824	Thioesterase
FSC02_RS08775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSC02_RS08790	COG2030	dehydratase
FSC02_RS08800	COG0183	Belongs to the thiolase family
FSC02_RS08815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSC02_RS08825	COG3135	benzoate transporter
FSC02_RS08835	COG0589	response to stress
FSC02_RS08840	COG0589	response to stress
FSC02_RS08850	COG0308	aminopeptidase N
FSC02_RS08880	COG0786	glutamate:sodium symporter activity
FSC02_RS08920	COG0477	Major facilitator Superfamily
FSC02_RS08935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FSC02_RS08945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSC02_RS08960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC02_RS08965	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS08985	COG3781	membrane
FSC02_RS08990	COG2890	protein-(glutamine-N5) methyltransferase activity
FSC02_RS08995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSC02_RS09010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC02_RS09035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSC02_RS09040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSC02_RS09045	COG1845	cytochrome c oxidase, subunit III
FSC02_RS09050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FSC02_RS09060	COG0360	Binds together with S18 to 16S ribosomal RNA
FSC02_RS09065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSC02_RS09080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSC02_RS09095	COG1305	Transglutaminase-like
FSC02_RS09105	COG2308	Evidence 4 Homologs of previously reported genes of
FSC02_RS09145	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FSC02_RS09150	COG0138	bifunctional purine biosynthesis protein purh
FSC02_RS09170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC02_RS09175	COG2011	ABC-type metal ion transport system permease component
FSC02_RS09205	COG1454	alcohol dehydrogenase
FSC02_RS09220	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSC02_RS09230	COG4122	O-methyltransferase activity
FSC02_RS09255	COG2274	protein secretion by the type I secretion system
FSC02_RS09265	COG1137	ATPase activity
FSC02_RS09270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FSC02_RS09280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FSC02_RS09285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSC02_RS09285	COG0517	IMP dehydrogenase activity
FSC02_RS09310	COG1643	Atp-dependent helicase
FSC02_RS09340	COG3634	alkyl hydroperoxide reductase activity
FSC02_RS09350	COG2391	methyltransferase activity
FSC02_RS09375	COG2070	2-Nitropropane dioxygenase
FSC02_RS09385	COG0675	Transposase, IS605 OrfB family
FSC02_RS09395	COG1278	Cold shock
FSC02_RS09470	COG1309	transcriptional regulator
FSC02_RS09475	COG0596	Alpha beta hydrolase
FSC02_RS09520	COG0352	thiamine-phosphate diphosphorylase activity
FSC02_RS09555	COG0612	Peptidase, M16
FSC02_RS09565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC02_RS09590	COG0739	heme binding
FSC02_RS09600	COG1187	pseudouridine synthase activity
FSC02_RS09615	COG1686	Belongs to the peptidase S11 family
FSC02_RS09620	COG1252	NADH dehydrogenase
FSC02_RS09625	COG1047	Peptidyl-prolyl cis-trans
FSC02_RS09650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSC02_RS09655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSC02_RS09665	COG0693	protein deglycase activity
FSC02_RS09670	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS09675	COG1301	dicarboxylic acid transport
FSC02_RS09690	COG3139	Protein of unknown function (DUF1315)
FSC02_RS09695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSC02_RS09700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC02_RS09720	COG0642	Histidine kinase
FSC02_RS09725	COG0745	RESPONSE REGULATOR receiver
FSC02_RS09735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSC02_RS09745	COG1720	tRNA m6t6A37 methyltransferase activity
FSC02_RS09770	COG0789	Transcriptional regulator
FSC02_RS09775	COG0431	NADPH-dependent FMN reductase
FSC02_RS09780	COG0798	PFAM Bile acid sodium symporter
FSC02_RS09790	COG0640	Transcriptional regulator
FSC02_RS09805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC02_RS09810	COG3634	alkyl hydroperoxide reductase activity
FSC02_RS09830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC02_RS09885	COG1131	(ABC) transporter
FSC02_RS09890	COG0842	Transport permease protein
FSC02_RS09905	COG2951	lytic endotransglycosylase activity
FSC02_RS09930	COG0052	Belongs to the universal ribosomal protein uS2 family
FSC02_RS09950	COG2175	clavaminate synthase activity
FSC02_RS09960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC02_RS09965	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS09980	COG1473	amidohydrolase
FSC02_RS09990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSC02_RS09995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSC02_RS10000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC02_RS10020	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FSC02_RS10050	COG2871	sodium ion transport
FSC02_RS10095	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC02_RS10095	COG1902	pentaerythritol trinitrate reductase activity
FSC02_RS10110	COG2203	Gaf domain
FSC02_RS10110	COG4251	negative regulation of phosphorylation
FSC02_RS10110	COG5001	Diguanylate cyclase
FSC02_RS10110	COG3706	GGDEF domain
FSC02_RS10115	COG0418	dihydroorotase activity
FSC02_RS10120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSC02_RS10140	COG0833	amino acid
FSC02_RS10170	COG4172	Belongs to the ABC transporter superfamily
FSC02_RS10175	COG4239	(ABC) transporter, permease
FSC02_RS10180	COG4174	ABC transporter (Permease)
FSC02_RS10185	COG4166	transmembrane transport
FSC02_RS10190	COG1388	LysM domain
FSC02_RS10190	COG0741	lytic transglycosylase activity
FSC02_RS10205	COG2816	NAD+ diphosphatase activity
FSC02_RS10240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC02_RS10245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC02_RS10255	COG0006	proline dipeptidase activity
FSC02_RS10260	COG3079	Belongs to the UPF0149 family
FSC02_RS10290	COG0277	FAD linked oxidase domain protein
FSC02_RS10300	COG2186	Transcriptional regulator
FSC02_RS10320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSC02_RS10330	COG2234	aminopeptidase activity
FSC02_RS10340	COG3384	dioxygenase
FSC02_RS10350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSC02_RS10355	COG2878	Part of a membrane complex involved in electron transport
FSC02_RS10360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSC02_RS10385	COG0768	penicillin binding
FSC02_RS10390	COG0742	ribosomal rna small subunit methyltransferase
FSC02_RS10405	COG0830	nickel cation binding
FSC02_RS10420	COG0804	urea catabolic process
FSC02_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS10455	COG3015	lipoprotein NlpE involved in copper resistance
FSC02_RS10475	COG1253	flavin adenine dinucleotide binding
FSC02_RS10495	COG3118	belongs to the thioredoxin family
FSC02_RS10530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSC02_RS10535	COG1773	rubredoxin
FSC02_RS10540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC02_RS10550	COG0583	DNA-binding transcription factor activity
FSC02_RS10565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC02_RS10575	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FSC02_RS10580	COG4181	ATPase activity
FSC02_RS10605	COG4771	TonB-dependent receptor
FSC02_RS10625	COG0306	phosphate transporter
FSC02_RS10635	COG2066	Belongs to the glutaminase family
FSC02_RS10645	COG0477	Major facilitator Superfamily
FSC02_RS10675	COG2199	diguanylate cyclase activity
FSC02_RS10675	COG2203	Gaf domain
FSC02_RS10685	COG4681	YaeQ
FSC02_RS10690	COG0523	cobalamin synthesis protein
FSC02_RS10710	COG0583	DNA-binding transcription factor activity
FSC02_RS10715	COG2814	Major facilitator Superfamily
FSC02_RS10725	COG1607	acyl-coa hydrolase
FSC02_RS10735	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC02_RS10740	COG2059	Chromate
FSC02_RS10745	COG1115	amino acid carrier protein
FSC02_RS10750	COG0786	glutamate:sodium symporter activity
FSC02_RS10765	COG2814	Major facilitator Superfamily
FSC02_RS10770	COG1289	transmembrane transporter activity
FSC02_RS10780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSC02_RS10835	COG1376	ErfK ybiS ycfS ynhG family protein
FSC02_RS10840	COG2832	Protein of unknown function (DUF454)
FSC02_RS10850	COG5510	response to toxic substance
FSC02_RS10865	COG0643	Histidine kinase
FSC02_RS10865	COG0784	Response regulator, receiver
FSC02_RS10865	COG2198	Histidine kinase
FSC02_RS10870	COG0840	transmembrane signaling receptor activity
FSC02_RS10905	COG0442	prolyl-tRNA aminoacylation
FSC02_RS10940	COG2358	TRAP transporter, solute receptor (TAXI family
FSC02_RS10965	COG0489	protein tyrosine kinase activity
FSC02_RS10970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC02_RS10970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC02_RS10980	COG3328	transposase activity
FSC02_RS10995	COG0004	ammonium transporteR
FSC02_RS11010	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FSC02_RS11025	COG2081	HI0933 family
FSC02_RS11035	COG0668	transmembrane transport
FSC02_RS11060	COG0583	DNA-binding transcription factor activity
FSC02_RS11065	COG1278	Cold shock
FSC02_RS11080	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC02_RS11085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC02_RS11090	COG0713	ATP synthesis coupled electron transport
FSC02_RS11095	COG0839	Belongs to the complex I subunit 6 family
FSC02_RS11100	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC02_RS11105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FSC02_RS11115	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSC02_RS11135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC02_RS11145	COG0142	geranyltranstransferase activity
FSC02_RS11150	COG2828	Protein conserved in bacteria
FSC02_RS11155	COG1113	amino acid transport
FSC02_RS11175	COG4372	Transposase
FSC02_RS11185	COG2963	transposase activity
FSC02_RS11190	COG3547	Transposase (IS116 IS110 IS902 family)
FSC02_RS11205	COG0625	glutathione transferase activity
FSC02_RS11245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC02_RS11255	COG1530	ribonuclease E activity
FSC02_RS11260	COG0424	maF-like protein
FSC02_RS11265	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FSC02_RS11270	COG1792	Involved in formation and maintenance of cell shape
FSC02_RS11275	COG1077	Cell shape determining protein MreB Mrl
FSC02_RS11280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC02_RS11285	COG0154	amidase activity
FSC02_RS11290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC02_RS11330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FSC02_RS11345	COG1215	transferase activity, transferring glycosyl groups
FSC02_RS11350	COG1649	PFAM Uncharacterised BCR, COG1649
FSC02_RS11350	COG0726	polysaccharide deacetylase
FSC02_RS11385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC02_RS11400	COG2814	Major facilitator Superfamily
FSC02_RS11405	COG1024	Enoyl-CoA hydratase
FSC02_RS11410	COG1012	belongs to the aldehyde dehydrogenase family
FSC02_RS11420	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS11450	COG3485	protocatechuate 3,4-dioxygenase
FSC02_RS11455	COG3485	protocatechuate 3,4-dioxygenase
FSC02_RS11460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSC02_RS11465	COG0596	Alpha beta hydrolase
FSC02_RS11470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSC02_RS11475	COG0183	Belongs to the thiolase family
FSC02_RS11480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC02_RS11485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC02_RS11490	COG1414	Transcriptional regulator
FSC02_RS11495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC02_RS11500	COG1414	Transcriptional regulator
FSC02_RS11565	COG3188	usher protein
FSC02_RS11645	COG0582	viral genome integration into host DNA
FSC02_RS11655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSC02_RS11660	COG2050	protein possibly involved in aromatic compounds catabolism
FSC02_RS11680	COG0420	3'-5' exonuclease activity
FSC02_RS11710	COG0735	belongs to the Fur family
FSC02_RS11715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC02_RS11720	COG2914	Belongs to the UPF0125 (RnfH) family
FSC02_RS11735	COG0121	glutamine amidotransferase
FSC02_RS11750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC02_RS11760	COG0210	DNA helicase
FSC02_RS11765	COG2885	chlorophyll binding
FSC02_RS11770	COG0204	Acyl-transferase
FSC02_RS11780	COG0850	regulation of cytokinetic process
FSC02_RS11785	COG2894	cell division
FSC02_RS11800	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSC02_RS11800	COG1674	ftsk spoiiie
FSC02_RS11805	COG0492	ferredoxin-NADP+ reductase activity
FSC02_RS11810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSC02_RS11820	COG0456	acetyltransferase
FSC02_RS11845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSC02_RS11865	COG1113	amino acid transport
FSC02_RS11870	COG0251	oxidation-reduction process
FSC02_RS11895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC02_RS11895	COG0352	thiamine-phosphate diphosphorylase activity
FSC02_RS11895	COG0351	phosphomethylpyrimidine kinase
FSC02_RS11910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSC02_RS11915	COG2076	Multidrug Resistance protein
FSC02_RS11925	COG2132	Multicopper oxidase
FSC02_RS11935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSC02_RS11950	COG4269	membrane
FSC02_RS11970	COG1968	undecaprenyl-diphosphatase activity
FSC02_RS11975	COG1214	PFAM Peptidase M22, glycoprotease
FSC02_RS11985	COG0494	nUDIX hydrolase
FSC02_RS12035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSC02_RS12040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSC02_RS12070	COG4372	Transposase
FSC02_RS12080	COG2963	transposase activity
FSC02_RS12120	COG2199	diguanylate cyclase activity
FSC02_RS12150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSC02_RS12155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSC02_RS12170	COG0450	alkyl hydroperoxide reductase
FSC02_RS12185	COG0285	dihydrofolate synthase activity
FSC02_RS12190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSC02_RS12235	COG4206	TonB-dependent receptor
FSC02_RS12240	COG2096	Adenosyltransferase
FSC02_RS12260	COG3385	transposase activity
FSC02_RS12265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FSC02_RS12270	COG2315	Protein conserved in bacteria
FSC02_RS12280	COG0745	RESPONSE REGULATOR receiver
FSC02_RS12285	COG2205	protein histidine kinase activity
FSC02_RS12295	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS12300	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS12305	COG3223	Belongs to the PsiE family
FSC02_RS12335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSC02_RS12350	COG1215	transferase activity, transferring glycosyl groups
FSC02_RS12370	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSC02_RS12420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSC02_RS12425	COG5002	protein histidine kinase activity
FSC02_RS12435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FSC02_RS12455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FSC02_RS12460	COG3328	transposase activity
FSC02_RS12475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC02_RS12480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC02_RS12490	COG3328	transposase activity
FSC02_RS12500	COG4372	Transposase
FSC02_RS12510	COG2963	transposase activity
FSC02_RS12530	COG0582	viral genome integration into host DNA
FSC02_RS12540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSC02_RS12550	COG1704	LemA family
FSC02_RS12555	COG5001	Diguanylate cyclase
FSC02_RS12555	COG2203	Gaf domain
FSC02_RS12555	COG4251	negative regulation of phosphorylation
FSC02_RS12555	COG3706	GGDEF domain
FSC02_RS12565	COG1862	Preprotein translocase
FSC02_RS12580	COG3385	transposase activity
FSC02_RS12590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC02_RS12605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC02_RS12610	COG0784	Response regulator, receiver
FSC02_RS12610	COG5002	protein histidine kinase activity
FSC02_RS12610	COG2205	protein histidine kinase activity
FSC02_RS12615	COG1024	Enoyl-CoA hydratase
FSC02_RS12625	COG3622	Belongs to the hyi family
FSC02_RS12650	COG0697	spore germination
FSC02_RS12655	COG2814	Major facilitator Superfamily
FSC02_RS12705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FSC02_RS12730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FSC02_RS12800	COG1785	Belongs to the alkaline phosphatase family
FSC02_RS12805	COG1785	Belongs to the alkaline phosphatase family
FSC02_RS12845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSC02_RS12850	COG3385	transposase activity
FSC02_RS12855	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FSC02_RS12860	COG0084	hydrolase, TatD family'
FSC02_RS12875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSC02_RS12890	COG0793	Belongs to the peptidase S41A family
FSC02_RS12920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSC02_RS12925	COG0280	phosphate acetyltransferase
FSC02_RS12925	COG0857	belongs to the CobB CobQ family
FSC02_RS12935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC02_RS12935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC02_RS12950	COG0740	serine-type endopeptidase activity
FSC02_RS12960	COG4771	TonB-dependent receptor
FSC02_RS12965	COG4774	siderophore transport
FSC02_RS12970	COG3128	pkhd-type hydroxylase
FSC02_RS12980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSC02_RS12985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC02_RS12990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC02_RS12990	COG2813	Specifically methylates the guanine in position
FSC02_RS13050	COG3040	lipid binding
FSC02_RS13080	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSC02_RS13115	COG0557	exoribonuclease II activity
FSC02_RS13120	COG0339	signal peptide processing
FSC02_RS13125	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FSC02_RS13155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FSC02_RS13180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FSC02_RS13185	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS13190	COG2072	flavoprotein involved in K transport
FSC02_RS13200	COG0202	RNA polymerase activity
FSC02_RS13205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSC02_RS13240	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSC02_RS13250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSC02_RS13255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSC02_RS13290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSC02_RS13320	COG0088	Forms part of the polypeptide exit tunnel
FSC02_RS13345	COG0433	COG0433 Predicted ATPase
FSC02_RS13355	COG1959	2 iron, 2 sulfur cluster binding
FSC02_RS13375	COG1301	dicarboxylic acid transport
FSC02_RS13380	COG1946	Acyl-CoA thioesterase
FSC02_RS13385	COG2937	Belongs to the GPAT DAPAT family
FSC02_RS13395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSC02_RS13400	COG1040	competence protein
FSC02_RS13415	COG0598	Magnesium transport protein CorA
FSC02_RS13425	COG2854	intermembrane phospholipid transfer
FSC02_RS13430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSC02_RS13435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSC02_RS13440	COG1127	ABC transporter
FSC02_RS13465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC02_RS13485	COG1960	acyl-CoA dehydrogenase activity
FSC02_RS13490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC02_RS13500	COG0534	Mate efflux family protein
FSC02_RS13505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC02_RS13510	COG0254	rRNA binding
FSC02_RS13515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSC02_RS13535	COG2226	methyltransferase
FSC02_RS13575	COG1192	Involved in chromosome partitioning
FSC02_RS13580	COG0628	permease
FSC02_RS13590	COG2814	Major facilitator Superfamily
FSC02_RS13610	COG0277	FAD linked oxidase domain protein
FSC02_RS13615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSC02_RS13640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSC02_RS13645	COG5380	lipid catabolic process
FSC02_RS13650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC02_RS13655	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC02_RS13670	COG0335	large ribosomal subunit rRNA binding
FSC02_RS13680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSC02_RS13685	COG0228	four-way junction DNA binding
FSC02_RS13730	COG0194	GDP metabolic process
FSC02_RS13735	COG1758	RNA polymerase activity
FSC02_RS13740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC02_RS13760	COG3307	-O-antigen
FSC02_RS13785	COG1704	LemA family
FSC02_RS13795	COG0493	'glutamate synthase
FSC02_RS13800	COG0067	glutamate synthase
FSC02_RS13800	COG0069	glutamate synthase activity
FSC02_RS13800	COG0070	glutamate synthase
FSC02_RS13850	COG2226	methyltransferase
FSC02_RS13860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSC02_RS13865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSC02_RS13880	COG0275	rRNA processing
FSC02_RS13885	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC02_RS13895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC02_RS13915	COG0488	(ABC) transporter
FSC02_RS13925	COG4221	oxidoreductase activity
FSC02_RS13940	COG0745	RESPONSE REGULATOR receiver
FSC02_RS13945	COG2205	protein histidine kinase activity
FSC02_RS13950	COG0427	acetyl-CoA hydrolase
FSC02_RS13980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSC02_RS14000	COG0697	spore germination
FSC02_RS14015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FSC02_RS14060	COG3158	transport of potassium into the cell
FSC02_RS14100	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FSC02_RS14115	COG0629	single-stranded DNA binding
FSC02_RS14120	COG2814	Major facilitator Superfamily
FSC02_RS14130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC02_RS14135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSC02_RS14140	COG3706	GGDEF domain
FSC02_RS14150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC02_RS14170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC02_RS14175	COG3162	membrane
FSC02_RS14180	COG0784	Response regulator, receiver
FSC02_RS14180	COG2205	protein histidine kinase activity
FSC02_RS14195	COG0431	NADPH-dependent FMN reductase
FSC02_RS14205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC02_RS14210	COG0668	transmembrane transport
FSC02_RS14215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC02_RS14220	COG1519	Transferase
FSC02_RS14225	COG1902	pentaerythritol trinitrate reductase activity
FSC02_RS14245	COG3385	transposase activity
FSC02_RS14255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSC02_RS14280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC02_RS14280	COG0426	domain, Protein
FSC02_RS14285	COG2119	membrane
FSC02_RS14315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSC02_RS14325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FSC02_RS14335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC02_RS14350	COG0189	ligase activity
FSC02_RS14360	COG3328	transposase activity
FSC02_RS14365	COG4115	mRNA cleavage
FSC02_RS14410	COG0708	Exodeoxyribonuclease III
FSC02_RS14415	COG1393	Belongs to the ArsC family
FSC02_RS14430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FSC02_RS14435	COG3706	GGDEF domain
FSC02_RS14440	COG0625	glutathione transferase activity
FSC02_RS14455	COG3385	transposase activity
FSC02_RS14485	COG1247	-acetyltransferase
FSC02_RS14490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC02_RS14495	COG4266	Belongs to the allantoicase family
FSC02_RS14500	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FSC02_RS14520	COG3328	transposase activity
FSC02_RS14535	COG0471	metal ion transport
FSC02_RS14550	COG2205	protein histidine kinase activity
FSC02_RS14550	COG0784	Response regulator, receiver
FSC02_RS14575	COG0410	ABC transporter
FSC02_RS14580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC02_RS14605	COG3150	esterase
FSC02_RS14615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FSC02_RS14620	COG2918	glutathione biosynthetic process
FSC02_RS14635	COG2733	membrane
FSC02_RS14640	COG0436	Aminotransferase
FSC02_RS14645	COG0534	Mate efflux family protein
FSC02_RS14650	COG2175	clavaminate synthase activity
FSC02_RS14705	COG0753	catalase activity
FSC02_RS14725	COG3830	Belongs to the UPF0237 family
FSC02_RS14725	COG0560	Phosphoserine phosphatase
FSC02_RS14740	COG0385	Bile acid
FSC02_RS14745	COG1335	isochorismatase
FSC02_RS14750	COG2814	Major facilitator Superfamily
FSC02_RS14755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSC02_RS14765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSC02_RS14770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSC02_RS14775	COG2983	Belongs to the UPF0260 family
FSC02_RS14780	COG5487	UPF0391 membrane protein
FSC02_RS14795	COG1194	a g-specific adenine glycosylase
FSC02_RS14800	COG0739	heme binding
FSC02_RS14810	COG2818	Glycosylase
FSC02_RS14815	COG1064	alcohol dehydrogenase
FSC02_RS14835	COG3023	N-Acetylmuramoyl-L-alanine amidase
FSC02_RS14845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSC02_RS14850	COG1309	transcriptional regulator
FSC02_RS14860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC02_RS14865	COG0546	phosphoglycolate phosphatase activity
FSC02_RS14870	COG1028	Short-chain dehydrogenase reductase Sdr
FSC02_RS14905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSC02_RS14905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FSC02_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC02_RS14915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC02_RS14920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC02_RS14925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC02_RS14930	COG1116	anion transmembrane transporter activity
FSC02_RS14945	COG1309	transcriptional regulator
FSC02_RS14955	COG0196	riboflavin kinase activity
FSC02_RS14960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSC02_RS14965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSC02_RS14970	COG1047	Peptidyl-prolyl cis-trans
FSC02_RS14980	COG2133	pyrroloquinoline quinone binding
FSC02_RS14985	COG2814	Major facilitator Superfamily
FSC02_RS15015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSC02_RS15060	COG2951	lytic endotransglycosylase activity
FSC02_RS15065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSC02_RS15085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC02_RS15105	COG2388	GCN5-related N-acetyl-transferase
FSC02_RS15115	COG0861	Integral membrane protein TerC family
FSC02_RS15120	COG0402	S-adenosylhomocysteine deaminase activity
FSC02_RS15135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC02_RS15140	COG1230	cation diffusion facilitator family transporter
FSC02_RS15180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSC02_RS15185	COG0594	ribonuclease P activity
FSC02_RS15210	COG4974	Belongs to the 'phage' integrase family
FSC02_RS15260	COG1683	Conserved Protein
FSC02_RS15295	COG1230	cation diffusion facilitator family transporter
FSC02_RS15310	COG0582	viral genome integration into host DNA
FSC02_RS15410	COG1192	Involved in chromosome partitioning
FSC02_RS15490	COG2963	transposase activity
FSC02_RS15620	COG1660	Displays ATPase and GTPase activities
FSC02_RS15640	COG2826	transposase and inactivated derivatives, IS30 family
FSC02_RS15660	COG0673	inositol 2-dehydrogenase activity
FSC02_RS15740	COG1373	ATPase (AAA superfamily
FSC02_RS15820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC02_RS15845	COG3173	Aminoglycoside phosphotransferase
FSC02_RS15870	COG3077	Addiction module antitoxin, RelB DinJ family
FSC02_RS15915	COG4191	Histidine kinase
FSC02_RS16010	COG0488	(ABC) transporter