locus-tag	class	description
J0W32_RS00005	COG1192	Involved in chromosome partitioning
J0W32_RS00010	COG1475	DNA binding
J0W32_RS00015	COG0811	peptide transport
J0W32_RS00025	COG1132	(ABC) transporter
J0W32_RS00030	COG1663	tetraacyldisaccharide 4'-kinase activity
J0W32_RS00050	COG0084	hydrolase, TatD family'
J0W32_RS00085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J0W32_RS00115	COG0776	regulation of translation
J0W32_RS00125	COG0284	orotidine-5'-phosphate decarboxylase activity
J0W32_RS00130	COG2431	L-lysine efflux transmembrane transporter activity
J0W32_RS00145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J0W32_RS00150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J0W32_RS00170	COG1253	flavin adenine dinucleotide binding
J0W32_RS00175	COG3385	transposase activity
J0W32_RS00205	COG0583	DNA-binding transcription factor activity
J0W32_RS00220	COG3852	Histidine kinase
J0W32_RS00235	COG0233	cytoplasmic translational termination
J0W32_RS00240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J0W32_RS00245	COG0575	Belongs to the CDS family
J0W32_RS00260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J0W32_RS00280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J0W32_RS00310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J0W32_RS00315	COG0730	response to heat
J0W32_RS00320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J0W32_RS00325	COG2207	Transcriptional regulator
J0W32_RS00330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J0W32_RS00340	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS00345	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS00380	COG4890	Cyd operon protein YbgT
J0W32_RS00385	COG1294	oxidase, subunit
J0W32_RS00400	COG1585	Membrane protein implicated in regulation of membrane protease activity
J0W32_RS00410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0W32_RS00430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J0W32_RS00435	COG0569	domain protein
J0W32_RS00445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J0W32_RS00475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J0W32_RS00480	COG0542	response to heat
J0W32_RS00515	COG0372	Belongs to the citrate synthase family
J0W32_RS00525	COG1546	Belongs to the CinA family
J0W32_RS00525	COG1058	Belongs to the CinA family
J0W32_RS00570	COG2814	Major facilitator Superfamily
J0W32_RS00585	COG0439	Biotin carboxylase
J0W32_RS00590	COG0511	ligase activity, forming carbon-carbon bonds
J0W32_RS00625	COG0596	Alpha beta hydrolase
J0W32_RS00715	COG2801	Transposase and inactivated derivatives
J0W32_RS00725	COG0730	response to heat
J0W32_RS00730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J0W32_RS00735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J0W32_RS00745	COG2885	chlorophyll binding
J0W32_RS00765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J0W32_RS00795	COG1012	belongs to the aldehyde dehydrogenase family
J0W32_RS00800	COG1309	transcriptional regulator
J0W32_RS00805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J0W32_RS00820	COG1024	Enoyl-CoA hydratase
J0W32_RS00825	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS00830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J0W32_RS00855	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS00865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J0W32_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS00875	COG1846	Transcriptional regulator
J0W32_RS00880	COG2814	Major facilitator Superfamily
J0W32_RS00895	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS00900	COG3293	Transposase
J0W32_RS00915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J0W32_RS00915	COG0596	Alpha beta hydrolase
J0W32_RS00915	COG2226	methyltransferase
J0W32_RS00920	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS00930	COG1024	Enoyl-CoA hydratase
J0W32_RS00935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J0W32_RS00940	COG0235	Class ii aldolase
J0W32_RS00950	COG0183	Belongs to the thiolase family
J0W32_RS00955	COG1250	3-hydroxyacyl-CoA dehydrogenase
J0W32_RS00960	COG1024	Enoyl-CoA hydratase
J0W32_RS00965	COG2814	Major facilitator Superfamily
J0W32_RS00975	COG2814	Major facilitator Superfamily
J0W32_RS00980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J0W32_RS00985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J0W32_RS00990	COG2814	Major facilitator Superfamily
J0W32_RS00995	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS01000	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS01010	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J0W32_RS01010	COG0644	oxidoreductase
J0W32_RS01015	COG0515	serine threonine protein kinase
J0W32_RS01020	COG2116	formate transmembrane transporter activity
J0W32_RS01025	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
J0W32_RS01035	COG2223	nitrite transmembrane transporter activity
J0W32_RS01045	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS01075	COG2814	Major facilitator Superfamily
J0W32_RS01080	COG0583	DNA-binding transcription factor activity
J0W32_RS01085	COG4948	Mandelate Racemase Muconate Lactonizing
J0W32_RS01090	COG4829	muconolactone delta-isomerase
J0W32_RS01100	COG4638	Rieske (2fe-2S)
J0W32_RS01105	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J0W32_RS01110	COG0633	Ferredoxin
J0W32_RS01110	COG0543	2 iron, 2 sulfur cluster binding
J0W32_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS01120	COG3135	benzoate transporter
J0W32_RS01125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J0W32_RS01130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J0W32_RS01135	COG0183	Belongs to the thiolase family
J0W32_RS01140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J0W32_RS01160	COG0583	DNA-binding transcription factor activity
J0W32_RS01165	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J0W32_RS01195	COG0303	'Molybdopterin
J0W32_RS01200	COG0521	Mo-molybdopterin cofactor biosynthetic process
J0W32_RS01200	COG0315	cyclic pyranopterin monophosphate synthase activity
J0W32_RS01215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J0W32_RS01225	COG0243	molybdopterin cofactor binding
J0W32_RS01230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J0W32_RS01235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J0W32_RS01235	COG2146	nitrite reductase [NAD(P)H] activity
J0W32_RS01240	COG2223	nitrite transmembrane transporter activity
J0W32_RS01250	COG1116	anion transmembrane transporter activity
J0W32_RS01250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0W32_RS01255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J0W32_RS01260	COG2937	Belongs to the GPAT DAPAT family
J0W32_RS01265	COG0640	Transcriptional regulator
J0W32_RS01285	COG3122	Protein conserved in bacteria
J0W32_RS01290	COG0668	transmembrane transport
J0W32_RS01305	COG1132	(ABC) transporter
J0W32_RS01325	COG2814	Major facilitator Superfamily
J0W32_RS01335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J0W32_RS01345	COG1113	amino acid transport
J0W32_RS01360	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J0W32_RS01365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0W32_RS01415	COG1525	nuclease
J0W32_RS01425	COG1294	oxidase, subunit
J0W32_RS01430	COG1271	oxidase subunit
J0W32_RS01440	COG2814	Major facilitator Superfamily
J0W32_RS01445	COG2207	Transcriptional regulator
J0W32_RS01450	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS01480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0W32_RS01485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J0W32_RS01505	COG0583	DNA-binding transcription factor activity
J0W32_RS01515	COG1346	cytolysis
J0W32_RS01525	COG1283	sodium-dependent phosphate transmembrane transporter activity
J0W32_RS01535	COG0693	protein deglycase activity
J0W32_RS01580	COG0552	protein localization to endoplasmic reticulum
J0W32_RS01585	COG0612	Peptidase, M16
J0W32_RS01615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0W32_RS01615	COG0517	IMP dehydrogenase activity
J0W32_RS01615	COG0617	tRNA 3'-terminal CCA addition
J0W32_RS01620	COG0133	tryptophan synthase activity
J0W32_RS01630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J0W32_RS01650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J0W32_RS01705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0W32_RS01735	COG0822	iron-sulfur transferase activity
J0W32_RS01740	COG0316	Belongs to the HesB IscA family
J0W32_RS01770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J0W32_RS01785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J0W32_RS01790	COG0702	epimerase
J0W32_RS01800	COG3385	transposase activity
J0W32_RS01820	COG1218	3'(2'),5'-bisphosphate nucleotidase
J0W32_RS01825	COG1011	Hydrolase
J0W32_RS01830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J0W32_RS01840	COG2137	regulation of response to DNA damage stimulus
J0W32_RS01855	COG0772	Belongs to the SEDS family
J0W32_RS01870	COG0148	phosphopyruvate hydratase activity
J0W32_RS01900	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0W32_RS01900	COG1902	pentaerythritol trinitrate reductase activity
J0W32_RS01920	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS01925	COG0583	DNA-binding transcription factor activity
J0W32_RS01930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J0W32_RS01935	COG1027	Aspartate ammonia-lyase
J0W32_RS01940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0W32_RS01950	COG0506	proline dehydrogenase activity
J0W32_RS01950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J0W32_RS01950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J0W32_RS01970	COG3698	Phosphodiester glycosidase
J0W32_RS02010	COG0697	spore germination
J0W32_RS02035	COG0424	maF-like protein
J0W32_RS02040	COG2850	peptidyl-arginine hydroxylation
J0W32_RS02045	COG4585	Histidine kinase
J0W32_RS02055	COG0069	glutamate synthase activity
J0W32_RS02075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J0W32_RS02080	COG1454	alcohol dehydrogenase
J0W32_RS02085	COG0824	Thioesterase
J0W32_RS02090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J0W32_RS02100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J0W32_RS02105	COG2030	dehydratase
J0W32_RS02115	COG0183	Belongs to the thiolase family
J0W32_RS02130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J0W32_RS02150	COG3135	benzoate transporter
J0W32_RS02160	COG0589	response to stress
J0W32_RS02165	COG0589	response to stress
J0W32_RS02175	COG0308	aminopeptidase N
J0W32_RS02205	COG0786	glutamate:sodium symporter activity
J0W32_RS02245	COG0477	Major facilitator Superfamily
J0W32_RS02260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J0W32_RS02270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J0W32_RS02285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J0W32_RS02290	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS02310	COG3781	membrane
J0W32_RS02320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J0W32_RS02335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J0W32_RS02360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J0W32_RS02365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J0W32_RS02370	COG1845	cytochrome c oxidase, subunit III
J0W32_RS02375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J0W32_RS02385	COG0360	Binds together with S18 to 16S ribosomal RNA
J0W32_RS02390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J0W32_RS02405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J0W32_RS02420	COG1305	Transglutaminase-like
J0W32_RS02430	COG2308	Evidence 4 Homologs of previously reported genes of
J0W32_RS02470	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J0W32_RS02475	COG0138	bifunctional purine biosynthesis protein purh
J0W32_RS02495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0W32_RS02500	COG2011	ABC-type metal ion transport system permease component
J0W32_RS02530	COG1454	alcohol dehydrogenase
J0W32_RS02545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J0W32_RS02555	COG4122	O-methyltransferase activity
J0W32_RS02580	COG2274	protein secretion by the type I secretion system
J0W32_RS02590	COG1137	ATPase activity
J0W32_RS02595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J0W32_RS02605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J0W32_RS02610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J0W32_RS02610	COG0517	IMP dehydrogenase activity
J0W32_RS02635	COG1643	Atp-dependent helicase
J0W32_RS02665	COG3634	alkyl hydroperoxide reductase activity
J0W32_RS02675	COG3385	transposase activity
J0W32_RS02680	COG2391	methyltransferase activity
J0W32_RS02705	COG2070	2-Nitropropane dioxygenase
J0W32_RS02715	COG0675	Transposase, IS605 OrfB family
J0W32_RS02725	COG1278	Cold shock
J0W32_RS02765	COG1309	transcriptional regulator
J0W32_RS02770	COG0596	Alpha beta hydrolase
J0W32_RS02810	COG0352	thiamine-phosphate diphosphorylase activity
J0W32_RS02845	COG0612	Peptidase, M16
J0W32_RS02855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J0W32_RS02865	COG0739	heme binding
J0W32_RS02880	COG1187	pseudouridine synthase activity
J0W32_RS02895	COG1686	Belongs to the peptidase S11 family
J0W32_RS02900	COG1252	NADH dehydrogenase
J0W32_RS02905	COG1047	Peptidyl-prolyl cis-trans
J0W32_RS02935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J0W32_RS02940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J0W32_RS02950	COG0693	protein deglycase activity
J0W32_RS02955	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS02960	COG1301	dicarboxylic acid transport
J0W32_RS02970	COG3139	Protein of unknown function (DUF1315)
J0W32_RS02975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J0W32_RS02980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0W32_RS03015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J0W32_RS03030	COG1720	tRNA m6t6A37 methyltransferase activity
J0W32_RS03055	COG0789	Transcriptional regulator
J0W32_RS03060	COG0431	NADPH-dependent FMN reductase
J0W32_RS03065	COG0798	PFAM Bile acid sodium symporter
J0W32_RS03075	COG0640	Transcriptional regulator
J0W32_RS03085	COG0826	peptidase U32
J0W32_RS03090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0W32_RS03095	COG3634	alkyl hydroperoxide reductase activity
J0W32_RS03115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J0W32_RS03175	COG1131	(ABC) transporter
J0W32_RS03180	COG0842	Transport permease protein
J0W32_RS03195	COG2951	lytic endotransglycosylase activity
J0W32_RS03220	COG0052	Belongs to the universal ribosomal protein uS2 family
J0W32_RS03240	COG2175	clavaminate synthase activity
J0W32_RS03250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J0W32_RS03255	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS03280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J0W32_RS03285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J0W32_RS03290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J0W32_RS03310	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J0W32_RS03340	COG2871	sodium ion transport
J0W32_RS03385	COG1902	pentaerythritol trinitrate reductase activity
J0W32_RS03385	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0W32_RS03400	COG2203	Gaf domain
J0W32_RS03400	COG3706	GGDEF domain
J0W32_RS03400	COG5001	Diguanylate cyclase
J0W32_RS03400	COG4251	negative regulation of phosphorylation
J0W32_RS03405	COG0418	dihydroorotase activity
J0W32_RS03410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J0W32_RS03435	COG0833	amino acid
J0W32_RS03465	COG4172	Belongs to the ABC transporter superfamily
J0W32_RS03470	COG4239	(ABC) transporter, permease
J0W32_RS03475	COG4174	ABC transporter (Permease)
J0W32_RS03480	COG4166	transmembrane transport
J0W32_RS03485	COG1388	LysM domain
J0W32_RS03485	COG0741	lytic transglycosylase activity
J0W32_RS03500	COG2816	NAD+ diphosphatase activity
J0W32_RS03535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J0W32_RS03540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J0W32_RS03550	COG0006	proline dipeptidase activity
J0W32_RS03555	COG3079	Belongs to the UPF0149 family
J0W32_RS03590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J0W32_RS03600	COG2234	aminopeptidase activity
J0W32_RS03610	COG3384	dioxygenase
J0W32_RS03620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J0W32_RS03625	COG2878	Part of a membrane complex involved in electron transport
J0W32_RS03630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J0W32_RS03655	COG0768	penicillin binding
J0W32_RS03660	COG0742	ribosomal rna small subunit methyltransferase
J0W32_RS03675	COG0830	nickel cation binding
J0W32_RS03690	COG0804	urea catabolic process
J0W32_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS03725	COG3015	lipoprotein NlpE involved in copper resistance
J0W32_RS03745	COG1253	flavin adenine dinucleotide binding
J0W32_RS03770	COG3118	belongs to the thioredoxin family
J0W32_RS03805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0W32_RS03810	COG1773	rubredoxin
J0W32_RS03815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J0W32_RS03825	COG0583	DNA-binding transcription factor activity
J0W32_RS03835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0W32_RS03845	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J0W32_RS03850	COG4181	ATPase activity
J0W32_RS03875	COG0500	methyltransferase
J0W32_RS03880	COG4771	TonB-dependent receptor
J0W32_RS03905	COG0306	phosphate transporter
J0W32_RS03915	COG2066	Belongs to the glutaminase family
J0W32_RS03925	COG0477	Major facilitator Superfamily
J0W32_RS03955	COG2203	Gaf domain
J0W32_RS03955	COG2199	diguanylate cyclase activity
J0W32_RS03965	COG4681	YaeQ
J0W32_RS03970	COG0523	cobalamin synthesis protein
J0W32_RS03990	COG0583	DNA-binding transcription factor activity
J0W32_RS03995	COG2814	Major facilitator Superfamily
J0W32_RS04005	COG1607	acyl-coa hydrolase
J0W32_RS04015	COG1752	Esterase of the alpha-beta hydrolase superfamily
J0W32_RS04020	COG2059	Chromate
J0W32_RS04025	COG1115	amino acid carrier protein
J0W32_RS04030	COG0786	glutamate:sodium symporter activity
J0W32_RS04045	COG2814	Major facilitator Superfamily
J0W32_RS04050	COG1289	transmembrane transporter activity
J0W32_RS04060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J0W32_RS04115	COG1376	ErfK ybiS ycfS ynhG family protein
J0W32_RS04120	COG2832	Protein of unknown function (DUF454)
J0W32_RS04130	COG5510	response to toxic substance
J0W32_RS04145	COG2198	Histidine kinase
J0W32_RS04145	COG0784	Response regulator, receiver
J0W32_RS04145	COG0643	Histidine kinase
J0W32_RS04150	COG0840	transmembrane signaling receptor activity
J0W32_RS04185	COG0442	prolyl-tRNA aminoacylation
J0W32_RS04220	COG2358	TRAP transporter, solute receptor (TAXI family
J0W32_RS04235	COG0489	protein tyrosine kinase activity
J0W32_RS04240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J0W32_RS04240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J0W32_RS04255	COG0004	ammonium transporteR
J0W32_RS04270	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J0W32_RS04285	COG2081	HI0933 family
J0W32_RS04300	COG0668	transmembrane transport
J0W32_RS04330	COG0583	DNA-binding transcription factor activity
J0W32_RS04335	COG1278	Cold shock
J0W32_RS04340	COG1278	Cold shock
J0W32_RS04355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J0W32_RS04360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J0W32_RS04365	COG0713	ATP synthesis coupled electron transport
J0W32_RS04370	COG0839	Belongs to the complex I subunit 6 family
J0W32_RS04375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J0W32_RS04380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J0W32_RS04390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J0W32_RS04410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J0W32_RS04420	COG0142	geranyltranstransferase activity
J0W32_RS04425	COG2828	Protein conserved in bacteria
J0W32_RS04430	COG1113	amino acid transport
J0W32_RS04450	COG0625	glutathione transferase activity
J0W32_RS04490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J0W32_RS04500	COG1530	ribonuclease E activity
J0W32_RS04505	COG0424	maF-like protein
J0W32_RS04510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J0W32_RS04515	COG1792	Involved in formation and maintenance of cell shape
J0W32_RS04520	COG1077	Cell shape determining protein MreB Mrl
J0W32_RS04525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J0W32_RS04530	COG0154	amidase activity
J0W32_RS04535	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J0W32_RS04565	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J0W32_RS04580	COG1215	transferase activity, transferring glycosyl groups
J0W32_RS04585	COG0726	polysaccharide deacetylase
J0W32_RS04585	COG1649	PFAM Uncharacterised BCR, COG1649
J0W32_RS04610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J0W32_RS04615	COG2050	protein possibly involved in aromatic compounds catabolism
J0W32_RS04635	COG0420	3'-5' exonuclease activity
J0W32_RS04665	COG0735	belongs to the Fur family
J0W32_RS04670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J0W32_RS04675	COG2914	Belongs to the UPF0125 (RnfH) family
J0W32_RS04690	COG0121	glutamine amidotransferase
J0W32_RS04705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0W32_RS04715	COG0210	DNA helicase
J0W32_RS04720	COG2885	chlorophyll binding
J0W32_RS04725	COG0204	Acyl-transferase
J0W32_RS04735	COG0850	regulation of cytokinetic process
J0W32_RS04740	COG2894	cell division
J0W32_RS04755	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J0W32_RS04755	COG1674	ftsk spoiiie
J0W32_RS04760	COG0492	ferredoxin-NADP+ reductase activity
J0W32_RS04765	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J0W32_RS04775	COG0456	acetyltransferase
J0W32_RS04800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J0W32_RS04815	COG1981	membrane
J0W32_RS04820	COG1113	amino acid transport
J0W32_RS04825	COG0251	oxidation-reduction process
J0W32_RS04850	COG0351	phosphomethylpyrimidine kinase
J0W32_RS04850	COG0352	thiamine-phosphate diphosphorylase activity
J0W32_RS04850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J0W32_RS04865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J0W32_RS04870	COG2076	Multidrug Resistance protein
J0W32_RS04880	COG2132	Multicopper oxidase
J0W32_RS04890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J0W32_RS04905	COG4269	membrane
J0W32_RS04925	COG1968	undecaprenyl-diphosphatase activity
J0W32_RS04930	COG1214	PFAM Peptidase M22, glycoprotease
J0W32_RS04940	COG0494	nUDIX hydrolase
J0W32_RS04990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J0W32_RS04995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J0W32_RS05085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J0W32_RS05090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J0W32_RS05105	COG0450	alkyl hydroperoxide reductase
J0W32_RS05120	COG0285	dihydrofolate synthase activity
J0W32_RS05125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J0W32_RS05170	COG4206	TonB-dependent receptor
J0W32_RS05175	COG2096	Adenosyltransferase
J0W32_RS05195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J0W32_RS05200	COG2315	Protein conserved in bacteria
J0W32_RS05210	COG0745	RESPONSE REGULATOR receiver
J0W32_RS05215	COG2205	protein histidine kinase activity
J0W32_RS05225	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS05230	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS05235	COG3223	Belongs to the PsiE family
J0W32_RS05275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J0W32_RS05305	COG0463	Glycosyl transferase, family 2
J0W32_RS05325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J0W32_RS05330	COG5002	protein histidine kinase activity
J0W32_RS05345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J0W32_RS05355	COG1704	LemA family
J0W32_RS05370	COG1862	Preprotein translocase
J0W32_RS05390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J0W32_RS05405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J0W32_RS05410	COG0784	Response regulator, receiver
J0W32_RS05410	COG2205	protein histidine kinase activity
J0W32_RS05410	COG5002	protein histidine kinase activity
J0W32_RS05415	COG1024	Enoyl-CoA hydratase
J0W32_RS05425	COG3622	Belongs to the hyi family
J0W32_RS05450	COG0697	spore germination
J0W32_RS05455	COG2814	Major facilitator Superfamily
J0W32_RS05475	COG1058	Belongs to the CinA family
J0W32_RS05475	COG1546	Belongs to the CinA family
J0W32_RS05505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J0W32_RS05515	COG0732	type I restriction modification DNA specificity domain
J0W32_RS05525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J0W32_RS05595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J0W32_RS05600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J0W32_RS05605	COG0084	hydrolase, TatD family'
J0W32_RS05620	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J0W32_RS05630	COG0793	Belongs to the peptidase S41A family
J0W32_RS05660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J0W32_RS05665	COG0280	phosphate acetyltransferase
J0W32_RS05665	COG0857	belongs to the CobB CobQ family
J0W32_RS05685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J0W32_RS05685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J0W32_RS05700	COG0740	serine-type endopeptidase activity
J0W32_RS05710	COG4771	TonB-dependent receptor
J0W32_RS05715	COG4774	siderophore transport
J0W32_RS05720	COG3128	pkhd-type hydroxylase
J0W32_RS05730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J0W32_RS05735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J0W32_RS05740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J0W32_RS05740	COG2813	Specifically methylates the guanine in position
J0W32_RS05800	COG3040	lipid binding
J0W32_RS05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
J0W32_RS05865	COG0557	exoribonuclease II activity
J0W32_RS05870	COG0339	signal peptide processing
J0W32_RS05875	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J0W32_RS05885	COG0697	spore germination
J0W32_RS05890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J0W32_RS05915	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J0W32_RS05925	COG2072	flavoprotein involved in K transport
J0W32_RS05935	COG0202	RNA polymerase activity
J0W32_RS05940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J0W32_RS05975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J0W32_RS05985	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J0W32_RS05990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J0W32_RS06025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J0W32_RS06055	COG0088	Forms part of the polypeptide exit tunnel
J0W32_RS06080	COG0433	COG0433 Predicted ATPase
J0W32_RS06090	COG1959	2 iron, 2 sulfur cluster binding
J0W32_RS06110	COG1301	dicarboxylic acid transport
J0W32_RS06115	COG1946	Acyl-CoA thioesterase
J0W32_RS06120	COG2937	Belongs to the GPAT DAPAT family
J0W32_RS06130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J0W32_RS06135	COG1040	competence protein
J0W32_RS06150	COG0598	Magnesium transport protein CorA
J0W32_RS06160	COG2854	intermembrane phospholipid transfer
J0W32_RS06165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J0W32_RS06170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J0W32_RS06175	COG1127	ABC transporter
J0W32_RS06200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0W32_RS06205	COG0408	coproporphyrinogen oxidase activity
J0W32_RS06220	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS06230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0W32_RS06240	COG0534	Mate efflux family protein
J0W32_RS06245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J0W32_RS06250	COG0254	rRNA binding
J0W32_RS06255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J0W32_RS06275	COG2226	methyltransferase
J0W32_RS06290	COG1192	Involved in chromosome partitioning
J0W32_RS06295	COG0628	permease
J0W32_RS06305	COG2814	Major facilitator Superfamily
J0W32_RS06325	COG0277	FAD linked oxidase domain protein
J0W32_RS06330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J0W32_RS06355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J0W32_RS06360	COG5380	lipid catabolic process
J0W32_RS06365	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J0W32_RS06385	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J0W32_RS06390	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J0W32_RS06395	COG0335	large ribosomal subunit rRNA binding
J0W32_RS06405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J0W32_RS06410	COG0228	four-way junction DNA binding
J0W32_RS06445	COG4969	Belongs to the N-Me-Phe pilin family
J0W32_RS06455	COG0194	GDP metabolic process
J0W32_RS06460	COG1758	RNA polymerase activity
J0W32_RS06465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J0W32_RS06485	COG3307	-O-antigen
J0W32_RS06520	COG0275	rRNA processing
J0W32_RS06545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J0W32_RS06550	COG1704	LemA family
J0W32_RS06560	COG0493	'glutamate synthase
J0W32_RS06565	COG0070	glutamate synthase
J0W32_RS06565	COG0069	glutamate synthase activity
J0W32_RS06565	COG0067	glutamate synthase
J0W32_RS06615	COG3385	transposase activity
J0W32_RS06620	COG2226	methyltransferase
J0W32_RS06630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J0W32_RS06635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J0W32_RS06650	COG0275	rRNA processing
J0W32_RS06655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J0W32_RS06665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J0W32_RS06685	COG0488	(ABC) transporter
J0W32_RS06695	COG4221	oxidoreductase activity
J0W32_RS06725	COG0427	acetyl-CoA hydrolase
J0W32_RS06730	COG3385	transposase activity
J0W32_RS06760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J0W32_RS06780	COG0697	spore germination
J0W32_RS06795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J0W32_RS06835	COG3158	transport of potassium into the cell
J0W32_RS06860	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
J0W32_RS06885	COG0629	single-stranded DNA binding
J0W32_RS06890	COG2814	Major facilitator Superfamily
J0W32_RS06900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J0W32_RS06915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J0W32_RS06935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J0W32_RS06955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0W32_RS06960	COG3162	membrane
J0W32_RS06965	COG2205	protein histidine kinase activity
J0W32_RS06965	COG0784	Response regulator, receiver
J0W32_RS06980	COG0431	NADPH-dependent FMN reductase
J0W32_RS06995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J0W32_RS07000	COG0668	transmembrane transport
J0W32_RS07005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J0W32_RS07010	COG1519	Transferase
J0W32_RS07015	COG1902	pentaerythritol trinitrate reductase activity
J0W32_RS07040	COG3385	transposase activity
J0W32_RS07045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J0W32_RS07070	COG0426	domain, Protein
J0W32_RS07070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J0W32_RS07075	COG2119	membrane
J0W32_RS07105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J0W32_RS07115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J0W32_RS07125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0W32_RS07130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0W32_RS07135	COG0189	ligase activity
J0W32_RS07155	COG0708	Exodeoxyribonuclease III
J0W32_RS07160	COG1393	Belongs to the ArsC family
J0W32_RS07175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J0W32_RS07180	COG3706	GGDEF domain
J0W32_RS07185	COG0625	glutathione transferase activity
J0W32_RS07225	COG1247	-acetyltransferase
J0W32_RS07230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J0W32_RS07235	COG4266	Belongs to the allantoicase family
J0W32_RS07240	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J0W32_RS07250	COG0471	metal ion transport
J0W32_RS07290	COG3150	esterase
J0W32_RS07300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J0W32_RS07305	COG2918	glutathione biosynthetic process
J0W32_RS07320	COG2733	membrane
J0W32_RS07325	COG0436	Aminotransferase
J0W32_RS07330	COG0534	Mate efflux family protein
J0W32_RS07345	COG3293	Transposase
J0W32_RS07380	COG0753	catalase activity
J0W32_RS07400	COG0560	Phosphoserine phosphatase
J0W32_RS07400	COG3830	Belongs to the UPF0237 family
J0W32_RS07415	COG0385	Bile acid
J0W32_RS07420	COG1335	isochorismatase
J0W32_RS07425	COG2814	Major facilitator Superfamily
J0W32_RS07430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J0W32_RS07440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J0W32_RS07445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J0W32_RS07450	COG2983	Belongs to the UPF0260 family
J0W32_RS07455	COG5487	UPF0391 membrane protein
J0W32_RS07470	COG1194	a g-specific adenine glycosylase
J0W32_RS07475	COG0739	heme binding
J0W32_RS07485	COG2818	Glycosylase
J0W32_RS07490	COG1064	alcohol dehydrogenase
J0W32_RS07510	COG3023	N-Acetylmuramoyl-L-alanine amidase
J0W32_RS07520	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J0W32_RS07525	COG1309	transcriptional regulator
J0W32_RS07535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J0W32_RS07540	COG0546	phosphoglycolate phosphatase activity
J0W32_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS07570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J0W32_RS07570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J0W32_RS07575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0W32_RS07580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0W32_RS07585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J0W32_RS07590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J0W32_RS07595	COG1116	anion transmembrane transporter activity
J0W32_RS07600	COG1309	transcriptional regulator
J0W32_RS07615	COG0196	riboflavin kinase activity
J0W32_RS07620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J0W32_RS07630	COG1047	Peptidyl-prolyl cis-trans
J0W32_RS07640	COG2133	pyrroloquinoline quinone binding
J0W32_RS07645	COG2814	Major facilitator Superfamily
J0W32_RS07675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J0W32_RS07685	COG0657	acetylesterase activity
J0W32_RS07720	COG2951	lytic endotransglycosylase activity
J0W32_RS07730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J0W32_RS07750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0W32_RS07760	COG2388	GCN5-related N-acetyl-transferase
J0W32_RS07770	COG0861	Integral membrane protein TerC family
J0W32_RS07775	COG0402	S-adenosylhomocysteine deaminase activity
J0W32_RS07790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J0W32_RS07795	COG1230	cation diffusion facilitator family transporter
J0W32_RS07820	COG0706	membrane insertase activity
J0W32_RS07825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J0W32_RS07830	COG0594	ribonuclease P activity
J0W32_RS07840	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J0W32_RS07845	COG0592	DNA-directed DNA polymerase activity
J0W32_RS07855	COG0187	DNA topoisomerase II activity
J0W32_RS07860	COG1063	alcohol dehydrogenase
J0W32_RS07865	COG0488	(ABC) transporter
J0W32_RS07895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J0W32_RS07900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J0W32_RS07910	COG0737	Belongs to the 5'-nucleotidase family
J0W32_RS07940	COG2814	Major facilitator Superfamily
J0W32_RS07960	COG1012	belongs to the aldehyde dehydrogenase family
J0W32_RS07965	COG0733	neurotransmitter:sodium symporter activity
J0W32_RS07975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J0W32_RS07985	COG0129	dihydroxy-acid dehydratase activity
J0W32_RS07995	COG0129	dihydroxy-acid dehydratase activity
J0W32_RS08015	COG2233	PERMEase
J0W32_RS08025	COG1309	transcriptional regulator
J0W32_RS08030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J0W32_RS08085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J0W32_RS08110	COG0438	transferase activity, transferring glycosyl groups
J0W32_RS08120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0W32_RS08130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J0W32_RS08140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J0W32_RS08155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0W32_RS08165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J0W32_RS08175	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J0W32_RS08190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J0W32_RS08230	COG0659	secondary active sulfate transmembrane transporter activity
J0W32_RS08505	COG3173	Aminoglycoside phosphotransferase
J0W32_RS08515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0W32_RS08555	COG1570	exodeoxyribonuclease VII activity
J0W32_RS08570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0W32_RS08575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0W32_RS08640	COG3586	endonuclease activity
J0W32_RS08660	COG3756	Protein conserved in bacteria
J0W32_RS08695	COG0271	Belongs to the BolA IbaG family
J0W32_RS08705	COG1192	Involved in chromosome partitioning
J0W32_RS08720	COG0586	Pfam SNARE associated Golgi protein
J0W32_RS08725	COG2259	Doxx family
J0W32_RS08730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J0W32_RS08730	COG0519	Catalyzes the synthesis of GMP from XMP
J0W32_RS08770	COG0281	malic enzyme
J0W32_RS08840	COG2837	iron assimilation
J0W32_RS08850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J0W32_RS08855	COG1121	(ABC) transporter
J0W32_RS08905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J0W32_RS08940	COG0386	Belongs to the glutathione peroxidase family
J0W32_RS08945	COG0697	spore germination
J0W32_RS08955	COG0758	DNA mediated transformation
J0W32_RS09005	COG2814	Major facilitator Superfamily
J0W32_RS09025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0W32_RS09040	COG2814	Major facilitator Superfamily
J0W32_RS09060	COG1253	flavin adenine dinucleotide binding
J0W32_RS09070	COG2860	membrane
J0W32_RS09075	COG0477	Major facilitator Superfamily
J0W32_RS09085	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS09100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J0W32_RS09125	COG0347	Belongs to the P(II) protein family
J0W32_RS09130	COG0004	ammonium transporteR
J0W32_RS09140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J0W32_RS09140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J0W32_RS09155	COG0586	Pfam SNARE associated Golgi protein
J0W32_RS09180	COG0795	lipopolysaccharide-transporting ATPase activity
J0W32_RS09185	COG0795	lipopolysaccharide-transporting ATPase activity
J0W32_RS09190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J0W32_RS09195	COG0793	Belongs to the peptidase S41A family
J0W32_RS09210	COG2197	response regulator
J0W32_RS09220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J0W32_RS09235	COG4974	Belongs to the 'phage' integrase family
J0W32_RS09260	COG0772	Belongs to the SEDS family
J0W32_RS09270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J0W32_RS09275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J0W32_RS09280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J0W32_RS09285	COG0494	nUDIX hydrolase
J0W32_RS09320	COG3275	phosphorelay sensor kinase activity
J0W32_RS09330	COG0181	hydroxymethylbilane synthase activity
J0W32_RS09350	COG0824	Thioesterase
J0W32_RS09435	COG0081	regulation of translation
J0W32_RS09450	COG0085	RNA polymerase activity
J0W32_RS09455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J0W32_RS09475	COG2056	Na+-H+ antiporter family
J0W32_RS09490	COG0326	Molecular chaperone. Has ATPase activity
J0W32_RS09520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J0W32_RS09530	COG2233	PERMEase
J0W32_RS09540	COG1024	Enoyl-CoA hydratase
J0W32_RS09540	COG1250	3-hydroxyacyl-CoA dehydrogenase
J0W32_RS09570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J0W32_RS09575	COG1132	(ABC) transporter
J0W32_RS09590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J0W32_RS09600	COG0497	DNA recombination
J0W32_RS09605	COG3123	guanosine phosphorylase activity
J0W32_RS09610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0W32_RS09620	COG0237	dephospho-CoA kinase activity
J0W32_RS09670	COG0779	Required for maturation of 30S ribosomal subunits
J0W32_RS09675	COG0195	Participates in both transcription termination and antitermination
J0W32_RS09685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J0W32_RS09690	COG1320	monovalent cation:proton antiporter activity
J0W32_RS09695	COG2212	antiporter activity
J0W32_RS09700	COG1863	multisubunit Na H antiporter MnhE subunit
J0W32_RS09705	COG0651	ATP synthesis coupled electron transport
J0W32_RS09710	COG1006	Multisubunit Na H antiporter MnhC subunit
J0W32_RS09715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J0W32_RS09715	COG2111	Na H antiporter
J0W32_RS09730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J0W32_RS09740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J0W32_RS09770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J0W32_RS09775	COG1074	ATP-dependent DNA helicase activity
J0W32_RS09780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J0W32_RS09790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J0W32_RS09815	COG2841	Protein conserved in bacteria
J0W32_RS09820	COG0789	Transcriptional regulator
J0W32_RS09830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J0W32_RS09840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J0W32_RS09860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J0W32_RS09865	COG4535	Mg2 and Co2 transporter CorC
J0W32_RS09870	COG0425	Belongs to the sulfur carrier protein TusA family
J0W32_RS09960	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J0W32_RS09960	COG0644	oxidoreductase
J0W32_RS09970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J0W32_RS09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J0W32_RS09995	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J0W32_RS10005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0W32_RS10005	COG0493	'glutamate synthase
J0W32_RS10015	COG2226	methyltransferase
J0W32_RS10030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J0W32_RS10050	COG4152	abc transporter atp-binding protein
J0W32_RS10060	COG0751	glycine-tRNA ligase activity
J0W32_RS10070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0W32_RS10070	COG0617	tRNA 3'-terminal CCA addition
J0W32_RS10070	COG0517	IMP dehydrogenase activity
J0W32_RS10075	COG1983	PspC domain protein
J0W32_RS10100	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS10105	COG1530	ribonuclease E activity
J0W32_RS10115	COG0546	phosphoglycolate phosphatase activity
J0W32_RS10120	COG3971	2-oxopent-4-enoate hydratase activity
J0W32_RS10125	COG4569	acetaldehyde dehydrogenase (acetylating) activity
J0W32_RS10150	COG0583	DNA-binding transcription factor activity
J0W32_RS10155	COG4638	Rieske (2fe-2S)
J0W32_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS10175	COG3384	dioxygenase
J0W32_RS10180	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0W32_RS10195	COG0753	catalase activity
J0W32_RS10205	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS10225	COG0494	nUDIX hydrolase
J0W32_RS10240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J0W32_RS10255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J0W32_RS10270	COG0473	3-isopropylmalate dehydrogenase activity
J0W32_RS10320	COG1560	Kdo2-lipid A biosynthetic process
J0W32_RS10325	COG0488	(ABC) transporter
J0W32_RS10330	COG2900	Belongs to the SlyX family
J0W32_RS10360	COG1929	Belongs to the glycerate kinase type-1 family
J0W32_RS10370	COG0210	DNA helicase
J0W32_RS10375	COG0724	RNA recognition motif
J0W32_RS10390	COG4651	solute:proton antiporter activity
J0W32_RS10390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J0W32_RS10415	COG0788	formyltetrahydrofolate deformylase activity
J0W32_RS10445	COG1295	ribonuclease BN
J0W32_RS10495	COG1702	phosphate starvation-inducible protein PhoH
J0W32_RS10505	COG1196	nuclear chromosome segregation
J0W32_RS10505	COG0741	lytic transglycosylase activity
J0W32_RS10505	COG0739	heme binding
J0W32_RS10545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J0W32_RS10550	COG1183	phosphatidylcholine synthase activity
J0W32_RS10615	COG1607	acyl-coa hydrolase
J0W32_RS10625	COG1666	GTP binding
J0W32_RS10645	COG2350	Protein conserved in bacteria
J0W32_RS10655	COG0613	PHP domain protein
J0W32_RS10660	COG3781	membrane
J0W32_RS10670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J0W32_RS10680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J0W32_RS10690	COG1162	GTPase activity
J0W32_RS10695	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J0W32_RS10795	COG1136	(ABC) transporter
J0W32_RS10795	COG0577	efflux transmembrane transporter activity
J0W32_RS10800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J0W32_RS10805	COG2703	oxygen carrier activity
J0W32_RS10830	COG0028	Belongs to the TPP enzyme family
J0W32_RS10835	COG0440	acetolactate synthase activity
J0W32_RS10875	COG2975	iron-sulfur cluster assembly
J0W32_RS10905	COG0124	histidyl-tRNA synthetase
J0W32_RS10915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J0W32_RS10930	COG3956	TIGRFAM MazG family protein
J0W32_RS10935	COG1555	photosystem II stabilization
J0W32_RS10940	COG0617	tRNA 3'-terminal CCA addition
J0W32_RS10945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J0W32_RS10960	COG1660	Displays ATPase and GTPase activities
J0W32_RS10970	COG3028	Belongs to the UPF0307 family
J0W32_RS10975	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS10990	COG0625	glutathione transferase activity
J0W32_RS10995	COG1238	metal cluster binding
J0W32_RS11030	COG0072	phenylalanine-tRNA ligase activity
J0W32_RS11055	COG0248	Ppx GppA phosphatase
J0W32_RS11065	COG0037	tRNA processing
J0W32_RS11110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J0W32_RS11160	COG2969	positive regulation of protein catabolic process
J0W32_RS11165	COG0625	glutathione transferase activity
J0W32_RS11170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J0W32_RS11180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J0W32_RS11185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J0W32_RS11190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J0W32_RS11220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J0W32_RS11230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0W32_RS11235	COG1408	metallophosphoesterase
J0W32_RS11245	COG0477	Major facilitator Superfamily
J0W32_RS11250	COG1272	protein, Hemolysin III
J0W32_RS11275	COG1250	3-hydroxyacyl-CoA dehydrogenase
J0W32_RS11275	COG1024	Enoyl-CoA hydratase
J0W32_RS11280	COG0183	Belongs to the thiolase family
J0W32_RS11285	COG2207	Transcriptional regulator
J0W32_RS11290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J0W32_RS11295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J0W32_RS11310	COG0183	Belongs to the thiolase family
J0W32_RS11330	COG0833	amino acid
J0W32_RS11340	COG2233	PERMEase
J0W32_RS11345	COG1217	gtp-binding protein TYPA
J0W32_RS11350	COG1970	mechanosensitive ion channel activity
J0W32_RS11355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0W32_RS11365	COG1877	trehalose-phosphatase activity
J0W32_RS11370	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
J0W32_RS11380	COG0363	glucosamine-6-phosphate deaminase activity
J0W32_RS11410	COG0354	folic acid binding
J0W32_RS11440	COG0346	lactoylglutathione lyase activity
J0W32_RS11445	COG0564	pseudouridine synthase activity
J0W32_RS11460	COG3189	MarR family transcriptional regulator
J0W32_RS11465	COG2824	Alkylphosphonate utilization operon protein PhnA
J0W32_RS11475	COG0628	permease
J0W32_RS11500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J0W32_RS11520	COG0730	response to heat
J0W32_RS11530	COG1196	nuclear chromosome segregation
J0W32_RS11535	COG3115	cell septum assembly
J0W32_RS11540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J0W32_RS11545	COG2193	ferroxidase activity
J0W32_RS11550	COG0596	Alpha beta hydrolase
J0W32_RS11550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J0W32_RS11550	COG2226	methyltransferase
J0W32_RS11565	COG4106	trans-aconitate 2-methyltransferase activity
J0W32_RS11580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J0W32_RS11585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J0W32_RS11595	COG0009	L-threonylcarbamoyladenylate synthase
J0W32_RS11600	COG3101	peptidyl-lysine hydroxylation
J0W32_RS11605	COG1399	metal-binding, possibly nucleic acid-binding protein
J0W32_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS11630	COG1652	LysM domain
J0W32_RS11635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J0W32_RS11645	COG0745	RESPONSE REGULATOR receiver
J0W32_RS11650	COG2205	protein histidine kinase activity
J0W32_RS11655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0W32_RS11670	COG1752	Esterase of the alpha-beta hydrolase superfamily
J0W32_RS11685	COG3338	carbonate dehydratase activity
J0W32_RS11690	COG1126	abc transporter atp-binding protein
J0W32_RS11695	COG0765	amino acid transport
J0W32_RS11700	COG0765	amino acid transport
J0W32_RS11710	COG2323	membrane
J0W32_RS11725	COG2852	Protein conserved in bacteria
J0W32_RS11740	COG0525	valine-tRNA ligase activity
J0W32_RS11755	COG0393	Putative heavy-metal-binding
J0W32_RS11760	COG0393	Putative heavy-metal-binding
J0W32_RS11770	COG1538	Outer membrane efflux protein
J0W32_RS11780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J0W32_RS11785	COG0671	phosphoesterase, PA-phosphatase related
J0W32_RS11810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J0W32_RS11820	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J0W32_RS11825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J0W32_RS11825	COG1648	precorrin-2 dehydrogenase activity
J0W32_RS11830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J0W32_RS11835	COG0531	amino acid
J0W32_RS11850	COG0321	lipoyl(octanoyl) transferase activity
J0W32_RS11860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J0W32_RS11885	COG0586	Pfam SNARE associated Golgi protein
J0W32_RS11925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J0W32_RS11955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J0W32_RS11970	COG0358	DNA primase activity
J0W32_RS11980	COG0564	pseudouridine synthase activity
J0W32_RS11995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J0W32_RS12005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0W32_RS12035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J0W32_RS12035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J0W32_RS12050	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J0W32_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
J0W32_RS12065	COG2072	flavoprotein involved in K transport
J0W32_RS12080	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J0W32_RS12085	COG1053	succinate dehydrogenase
J0W32_RS12090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J0W32_RS12105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J0W32_RS12115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J0W32_RS12125	COG1649	PFAM Uncharacterised BCR, COG1649
J0W32_RS12125	COG0726	polysaccharide deacetylase
J0W32_RS12130	COG1215	transferase activity, transferring glycosyl groups
J0W32_RS12140	COG2268	Band 7 protein
J0W32_RS12155	COG2354	Protein conserved in bacteria
J0W32_RS12160	COG2321	neutral zinc metallopeptidase
J0W32_RS12170	COG0589	response to stress
J0W32_RS12175	COG0110	maltose O-acetyltransferase activity
J0W32_RS12180	COG0415	Belongs to the DNA photolyase family
J0W32_RS12195	COG0505	Belongs to the CarA family
J0W32_RS12210	COG1534	Rna-binding protein
J0W32_RS12220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J0W32_RS12230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J0W32_RS12265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J0W32_RS12285	COG1597	lipid kinase activity
J0W32_RS12310	COG0584	glycerophosphoryl diester phosphodiesterase
J0W32_RS12320	COG2239	Acts as a magnesium transporter
J0W32_RS12330	COG0501	Belongs to the peptidase M48B family
J0W32_RS12335	COG1196	nuclear chromosome segregation
J0W32_RS12335	COG0739	heme binding
J0W32_RS12335	COG0741	lytic transglycosylase activity
J0W32_RS12340	COG0037	tRNA processing
J0W32_RS12350	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J0W32_RS12355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J0W32_RS12375	COG1840	ABC-type Fe3 transport system, periplasmic component
J0W32_RS12380	COG3842	ATPase activity
J0W32_RS12385	COG1741	Belongs to the pirin family
J0W32_RS12395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J0W32_RS12400	COG3739	integral membrane protein
J0W32_RS12415	COG3706	GGDEF domain
J0W32_RS12425	COG0302	gtp cyclohydrolase
J0W32_RS12445	COG0512	Glutamine amidotransferase of anthranilate synthase
J0W32_RS12450	COG0174	glutamine synthetase
J0W32_RS12460	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J0W32_RS12470	COG0583	DNA-binding transcription factor activity
J0W32_RS12505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J0W32_RS12510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J0W32_RS12530	COG1115	amino acid carrier protein
J0W32_RS12535	COG1113	amino acid transport
J0W32_RS12545	COG0019	diaminopimelate decarboxylase activity
J0W32_RS12560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J0W32_RS12570	COG1522	sequence-specific DNA binding
J0W32_RS12575	COG1280	lysine exporter protein (LysE YggA)
J0W32_RS12615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J0W32_RS12640	COG1671	Belongs to the UPF0178 family
J0W32_RS12655	COG4591	ABC-type transport system involved in lipoprotein release permease component
J0W32_RS12660	COG1136	(ABC) transporter
J0W32_RS12665	COG2333	competence protein COMEC
J0W32_RS12665	COG0658	competence protein
J0W32_RS12685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J0W32_RS12690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J0W32_RS12695	COG0628	permease
J0W32_RS12700	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J0W32_RS12730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0W32_RS12745	COG3385	transposase activity
J0W32_RS12755	COG0823	Involved in the tonB-independent uptake of proteins
J0W32_RS12775	COG0824	Thioesterase
J0W32_RS12785	COG2255	four-way junction helicase activity
J0W32_RS12805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J0W32_RS12805	COG0047	phosphoribosylformylglycinamidine synthase activity
J0W32_RS12820	COG0778	Nitroreductase
J0W32_RS12825	COG1024	Enoyl-CoA hydratase
J0W32_RS12830	COG1056	cytidyltransferase-related domain
J0W32_RS12830	COG1051	belongs to the nudix hydrolase family
J0W32_RS12835	COG2353	YceI-like domain
J0W32_RS12840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J0W32_RS12850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J0W32_RS12855	COG0602	queuosine metabolic process
J0W32_RS12875	COG0583	DNA-binding transcription factor activity
J0W32_RS12880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J0W32_RS12885	COG4208	sulfate ABC transporter
J0W32_RS12900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J0W32_RS12910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J0W32_RS12925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J0W32_RS12935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J0W32_RS12950	COG0681	Belongs to the peptidase S26 family
J0W32_RS12960	COG0571	ribonuclease III activity
J0W32_RS12965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J0W32_RS12975	COG1381	Involved in DNA repair and RecF pathway recombination
J0W32_RS12980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J0W32_RS13005	COG0436	Aminotransferase
J0W32_RS13015	COG3300	MHYT domain
J0W32_RS13015	COG5001	Diguanylate cyclase
J0W32_RS13025	COG0556	nucleotide-excision repair
J0W32_RS13055	COG0702	epimerase
J0W32_RS13060	COG1733	regulation of RNA biosynthetic process
J0W32_RS13065	COG2814	Major facilitator Superfamily
J0W32_RS13075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J0W32_RS13090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J0W32_RS13095	COG0076	glutamate decarboxylase activity
J0W32_RS13110	COG0573	inorganic phosphate transmembrane transporter activity
J0W32_RS13120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J0W32_RS13125	COG0616	signal peptide processing
J0W32_RS13165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J0W32_RS13170	COG1686	Belongs to the peptidase S11 family
J0W32_RS13185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J0W32_RS13195	COG0583	DNA-binding transcription factor activity
J0W32_RS13200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J0W32_RS13205	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J0W32_RS13210	COG1067	ATP-dependent peptidase activity
J0W32_RS13245	COG1509	lysine 2,3-aminomutase activity
J0W32_RS13250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J0W32_RS13255	COG1966	Carbon starvation protein
J0W32_RS13260	COG2879	small protein
J0W32_RS13265	COG0714	Associated with various cellular activities
J0W32_RS13295	COG2252	PERMEase
J0W32_RS13300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J0W32_RS13310	COG1215	transferase activity, transferring glycosyl groups
J0W32_RS13320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J0W32_RS13330	COG0527	aspartate kinase activity
J0W32_RS13340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J0W32_RS13355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J0W32_RS13360	COG0501	Belongs to the peptidase M48B family
J0W32_RS13375	COG0667	Aldo Keto reductase
J0W32_RS13385	COG1765	OsmC-like protein
J0W32_RS13405	COG0540	Belongs to the ATCase OTCase family
J0W32_RS13420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J0W32_RS13435	COG4770	biotin carboxylase activity
J0W32_RS13440	COG1024	Enoyl-CoA hydratase
J0W32_RS13445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J0W32_RS13450	COG1960	acyl-CoA dehydrogenase activity
J0W32_RS13455	COG1309	transcriptional regulator
J0W32_RS13460	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS13480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J0W32_RS13490	COG0659	secondary active sulfate transmembrane transporter activity
J0W32_RS13510	COG2363	Small membrane protein
J0W32_RS13530	COG0513	Belongs to the DEAD box helicase family
J0W32_RS13595	COG4783	chaperone-mediated protein folding
J0W32_RS13610	COG1610	YqeY-like protein
J0W32_RS13640	COG0515	serine threonine protein kinase
J0W32_RS13640	COG2815	serine threonine protein kinase
J0W32_RS13680	COG2755	lipolytic protein G-D-S-L family
J0W32_RS13680	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J0W32_RS13685	COG0436	Aminotransferase
J0W32_RS13690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J0W32_RS13695	COG0386	Belongs to the glutathione peroxidase family
J0W32_RS13705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J0W32_RS13720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J0W32_RS13730	COG0012	GTP binding
J0W32_RS13755	COG0204	Acyl-transferase
J0W32_RS13780	COG0783	Belongs to the Dps family
J0W32_RS13785	COG2814	Major facilitator Superfamily
J0W32_RS13790	COG2030	dehydratase
J0W32_RS13790	COG1012	belongs to the aldehyde dehydrogenase family
J0W32_RS13795	COG3396	Phenylacetate-CoA oxygenase
J0W32_RS13800	COG3460	Phenylacetate-CoA oxygenase
J0W32_RS13805	COG3396	Phenylacetate-CoA oxygenase
J0W32_RS13810	COG2151	metal-sulfur cluster biosynthetic enzyme
J0W32_RS13815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J0W32_RS13820	COG1024	Enoyl-CoA hydratase
J0W32_RS13825	COG1024	Enoyl-CoA hydratase
J0W32_RS13830	COG1250	3-hydroxyacyl-CoA dehydrogenase
J0W32_RS13835	COG0183	Belongs to the thiolase family
J0W32_RS13840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J0W32_RS13845	COG3327	negative regulation of DNA-templated transcription, initiation
J0W32_RS13855	COG0318	PFAM AMP-dependent synthetase and ligase
J0W32_RS13875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J0W32_RS13880	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J0W32_RS13880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J0W32_RS13885	COG1254	Belongs to the acylphosphatase family
J0W32_RS13920	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J0W32_RS13925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J0W32_RS13935	COG2353	YceI-like domain
J0W32_RS13940	COG0519	Catalyzes the synthesis of GMP from XMP
J0W32_RS13940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J0W32_RS13970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J0W32_RS13975	COG0583	DNA-binding transcription factor activity
J0W32_RS13985	COG2707	UPF0756 membrane protein
J0W32_RS14010	COG0802	atpase or kinase
J0W32_RS14015	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J0W32_RS14025	COG1923	regulation of RNA biosynthetic process
J0W32_RS14030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0W32_RS14045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J0W32_RS14055	COG1373	ATPase (AAA superfamily
J0W32_RS14200	COG4221	oxidoreductase activity
J0W32_RS14225	COG2801	Transposase and inactivated derivatives
J0W32_RS14270	COG3173	Aminoglycoside phosphotransferase
J0W32_RS14275	COG0488	(ABC) transporter
J0W32_RS14290	COG0488	(ABC) transporter
J0W32_RS14315	COG0582	viral genome integration into host DNA
J0W32_RS14370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0W32_RS14375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0W32_RS14390	COG1192	Involved in chromosome partitioning
J0W32_RS14400	COG2963	transposase activity
J0W32_RS14410	COG4372	Transposase