locus-tag	class	description
JYB86_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYB86_RS00010	COG0592	DNA-directed DNA polymerase activity
JYB86_RS00020	COG0187	DNA topoisomerase II activity
JYB86_RS00025	COG1063	alcohol dehydrogenase
JYB86_RS00045	COG0488	(ABC) transporter
JYB86_RS00085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JYB86_RS00090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JYB86_RS00115	COG0737	Belongs to the 5'-nucleotidase family
JYB86_RS00145	COG2814	Major facilitator Superfamily
JYB86_RS00155	COG1012	belongs to the aldehyde dehydrogenase family
JYB86_RS00160	COG0733	neurotransmitter:sodium symporter activity
JYB86_RS00170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JYB86_RS00185	COG0129	dihydroxy-acid dehydratase activity
JYB86_RS00205	COG2233	PERMEase
JYB86_RS00215	COG1309	transcriptional regulator
JYB86_RS00220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYB86_RS00275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JYB86_RS00290	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JYB86_RS00310	COG1216	Glycosyl transferase, family 2
JYB86_RS00315	COG0463	Glycosyl transferase, family 2
JYB86_RS00325	COG0367	asparagine synthase
JYB86_RS00335	COG0438	transferase activity, transferring glycosyl groups
JYB86_RS00340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYB86_RS00350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JYB86_RS00360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JYB86_RS00375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JYB86_RS00410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYB86_RS00420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JYB86_RS00435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JYB86_RS00585	COG4974	Belongs to the 'phage' integrase family
JYB86_RS00610	COG3173	Aminoglycoside phosphotransferase
JYB86_RS00620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYB86_RS00645	COG3077	Addiction module antitoxin, RelB DinJ family
JYB86_RS00655	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JYB86_RS00660	COG1335	isochorismatase
JYB86_RS00745	COG3756	Protein conserved in bacteria
JYB86_RS00780	COG0271	Belongs to the BolA IbaG family
JYB86_RS00790	COG1192	Involved in chromosome partitioning
JYB86_RS00805	COG0586	Pfam SNARE associated Golgi protein
JYB86_RS00810	COG2259	Doxx family
JYB86_RS00815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JYB86_RS00815	COG0519	Catalyzes the synthesis of GMP from XMP
JYB86_RS00820	COG1715	Restriction endonuclease
JYB86_RS00860	COG0281	malic enzyme
JYB86_RS00925	COG2837	iron assimilation
JYB86_RS00935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JYB86_RS00940	COG1121	(ABC) transporter
JYB86_RS00990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JYB86_RS01020	COG0386	Belongs to the glutathione peroxidase family
JYB86_RS01025	COG0697	spore germination
JYB86_RS01035	COG0758	DNA mediated transformation
JYB86_RS01085	COG2814	Major facilitator Superfamily
JYB86_RS01105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JYB86_RS01120	COG2814	Major facilitator Superfamily
JYB86_RS01145	COG1253	flavin adenine dinucleotide binding
JYB86_RS01155	COG2860	membrane
JYB86_RS01160	COG0477	Major facilitator Superfamily
JYB86_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS01185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JYB86_RS01200	COG0606	chelatase, subunit chli
JYB86_RS01210	COG0347	Belongs to the P(II) protein family
JYB86_RS01215	COG0004	ammonium transporteR
JYB86_RS01225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYB86_RS01225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JYB86_RS01240	COG0586	Pfam SNARE associated Golgi protein
JYB86_RS01265	COG0795	lipopolysaccharide-transporting ATPase activity
JYB86_RS01270	COG0795	lipopolysaccharide-transporting ATPase activity
JYB86_RS01275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JYB86_RS01280	COG0793	Belongs to the peptidase S41A family
JYB86_RS01295	COG2197	response regulator
JYB86_RS01305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JYB86_RS01320	COG4974	Belongs to the 'phage' integrase family
JYB86_RS01345	COG0772	Belongs to the SEDS family
JYB86_RS01355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYB86_RS01360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JYB86_RS01365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JYB86_RS01370	COG0494	nUDIX hydrolase
JYB86_RS01405	COG3275	phosphorelay sensor kinase activity
JYB86_RS01415	COG0181	hydroxymethylbilane synthase activity
JYB86_RS01435	COG0824	Thioesterase
JYB86_RS01520	COG0081	regulation of translation
JYB86_RS01535	COG0085	RNA polymerase activity
JYB86_RS01540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JYB86_RS01560	COG2056	Na+-H+ antiporter family
JYB86_RS01585	COG0326	Molecular chaperone. Has ATPase activity
JYB86_RS01620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JYB86_RS01630	COG2233	PERMEase
JYB86_RS01640	COG1024	Enoyl-CoA hydratase
JYB86_RS01640	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYB86_RS01660	COG0322	excinuclease ABC activity
JYB86_RS01670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JYB86_RS01675	COG1132	(ABC) transporter
JYB86_RS01690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JYB86_RS01700	COG0497	DNA recombination
JYB86_RS01705	COG3123	guanosine phosphorylase activity
JYB86_RS01710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYB86_RS01720	COG0237	dephospho-CoA kinase activity
JYB86_RS01770	COG0779	Required for maturation of 30S ribosomal subunits
JYB86_RS01775	COG0195	Participates in both transcription termination and antitermination
JYB86_RS01785	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JYB86_RS01800	COG4372	Transposase
JYB86_RS01805	COG1320	monovalent cation:proton antiporter activity
JYB86_RS01810	COG2212	antiporter activity
JYB86_RS01815	COG1863	multisubunit Na H antiporter MnhE subunit
JYB86_RS01820	COG0651	ATP synthesis coupled electron transport
JYB86_RS01825	COG1006	Multisubunit Na H antiporter MnhC subunit
JYB86_RS01830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JYB86_RS01830	COG2111	Na H antiporter
JYB86_RS01845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JYB86_RS01855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JYB86_RS01885	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JYB86_RS01890	COG1074	ATP-dependent DNA helicase activity
JYB86_RS01895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JYB86_RS01900	COG0675	Transposase, IS605 OrfB family
JYB86_RS01905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JYB86_RS01920	COG2841	Protein conserved in bacteria
JYB86_RS01925	COG0789	Transcriptional regulator
JYB86_RS01935	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JYB86_RS01945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JYB86_RS01975	COG4372	Transposase
JYB86_RS01980	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JYB86_RS01985	COG4535	Mg2 and Co2 transporter CorC
JYB86_RS01990	COG0425	Belongs to the sulfur carrier protein TusA family
JYB86_RS02045	COG4372	Transposase
JYB86_RS02110	COG2801	Transposase and inactivated derivatives
JYB86_RS02190	COG4372	Transposase
JYB86_RS02195	COG2801	Transposase and inactivated derivatives
JYB86_RS02200	COG0644	oxidoreductase
JYB86_RS02200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
JYB86_RS02210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JYB86_RS02225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JYB86_RS02235	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JYB86_RS02245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JYB86_RS02245	COG0493	'glutamate synthase
JYB86_RS02255	COG2226	methyltransferase
JYB86_RS02270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYB86_RS02315	COG0751	glycine-tRNA ligase activity
JYB86_RS02325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JYB86_RS02325	COG0617	tRNA 3'-terminal CCA addition
JYB86_RS02325	COG0517	IMP dehydrogenase activity
JYB86_RS02330	COG1983	PspC domain protein
JYB86_RS02355	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS02360	COG1530	ribonuclease E activity
JYB86_RS02370	COG0546	phosphoglycolate phosphatase activity
JYB86_RS02375	COG3971	2-oxopent-4-enoate hydratase activity
JYB86_RS02380	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JYB86_RS02405	COG0583	DNA-binding transcription factor activity
JYB86_RS02410	COG4638	Rieske (2fe-2S)
JYB86_RS02425	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS02430	COG3384	dioxygenase
JYB86_RS02435	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYB86_RS02450	COG0753	catalase activity
JYB86_RS02460	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS02480	COG0494	nUDIX hydrolase
JYB86_RS02495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JYB86_RS02510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JYB86_RS02525	COG0473	3-isopropylmalate dehydrogenase activity
JYB86_RS02580	COG1560	Kdo2-lipid A biosynthetic process
JYB86_RS02585	COG0488	(ABC) transporter
JYB86_RS02590	COG2900	Belongs to the SlyX family
JYB86_RS02650	COG0210	DNA helicase
JYB86_RS02655	COG0724	RNA recognition motif
JYB86_RS02670	COG4651	solute:proton antiporter activity
JYB86_RS02670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JYB86_RS02695	COG0788	formyltetrahydrofolate deformylase activity
JYB86_RS02725	COG1295	ribonuclease BN
JYB86_RS02775	COG1702	phosphate starvation-inducible protein PhoH
JYB86_RS02785	COG1196	nuclear chromosome segregation
JYB86_RS02785	COG0739	heme binding
JYB86_RS02785	COG0741	lytic transglycosylase activity
JYB86_RS02825	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JYB86_RS02830	COG1183	phosphatidylcholine synthase activity
JYB86_RS02895	COG1607	acyl-coa hydrolase
JYB86_RS02905	COG1666	GTP binding
JYB86_RS02925	COG2350	Protein conserved in bacteria
JYB86_RS02935	COG0613	PHP domain protein
JYB86_RS02940	COG3781	membrane
JYB86_RS02950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JYB86_RS02960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JYB86_RS02970	COG1162	GTPase activity
JYB86_RS02975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JYB86_RS03145	COG3385	transposase activity
JYB86_RS03190	COG1136	(ABC) transporter
JYB86_RS03190	COG0577	efflux transmembrane transporter activity
JYB86_RS03195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYB86_RS03220	COG0028	Belongs to the TPP enzyme family
JYB86_RS03225	COG0440	acetolactate synthase activity
JYB86_RS03265	COG2975	iron-sulfur cluster assembly
JYB86_RS03295	COG0124	histidyl-tRNA synthetase
JYB86_RS03305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JYB86_RS03320	COG3956	TIGRFAM MazG family protein
JYB86_RS03325	COG1555	photosystem II stabilization
JYB86_RS03330	COG0617	tRNA 3'-terminal CCA addition
JYB86_RS03335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JYB86_RS03350	COG1660	Displays ATPase and GTPase activities
JYB86_RS03360	COG3028	Belongs to the UPF0307 family
JYB86_RS03365	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS03380	COG0625	glutathione transferase activity
JYB86_RS03385	COG1238	metal cluster binding
JYB86_RS03420	COG0072	phenylalanine-tRNA ligase activity
JYB86_RS03445	COG0248	Ppx GppA phosphatase
JYB86_RS03455	COG0037	tRNA processing
JYB86_RS03500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYB86_RS03550	COG2969	positive regulation of protein catabolic process
JYB86_RS03555	COG0625	glutathione transferase activity
JYB86_RS03560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JYB86_RS03570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JYB86_RS03575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JYB86_RS03580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JYB86_RS03610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JYB86_RS03620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JYB86_RS03625	COG1408	metallophosphoesterase
JYB86_RS03635	COG0477	Major facilitator Superfamily
JYB86_RS03640	COG1272	protein, Hemolysin III
JYB86_RS03660	COG1024	Enoyl-CoA hydratase
JYB86_RS03660	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYB86_RS03665	COG0183	Belongs to the thiolase family
JYB86_RS03670	COG2207	Transcriptional regulator
JYB86_RS03675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JYB86_RS03680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYB86_RS03700	COG0183	Belongs to the thiolase family
JYB86_RS03720	COG0833	amino acid
JYB86_RS03730	COG2233	PERMEase
JYB86_RS03735	COG1217	gtp-binding protein TYPA
JYB86_RS03740	COG1970	mechanosensitive ion channel activity
JYB86_RS03745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JYB86_RS03755	COG1877	trehalose-phosphatase activity
JYB86_RS03760	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JYB86_RS03770	COG0363	glucosamine-6-phosphate deaminase activity
JYB86_RS03800	COG0354	folic acid binding
JYB86_RS03830	COG0346	lactoylglutathione lyase activity
JYB86_RS03835	COG0564	pseudouridine synthase activity
JYB86_RS03850	COG3189	MarR family transcriptional regulator
JYB86_RS03855	COG2824	Alkylphosphonate utilization operon protein PhnA
JYB86_RS03865	COG0628	permease
JYB86_RS03880	COG1764	response to oxidative stress
JYB86_RS03885	COG1846	Transcriptional regulator
JYB86_RS03900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JYB86_RS03920	COG0730	response to heat
JYB86_RS03930	COG1196	nuclear chromosome segregation
JYB86_RS03935	COG3115	cell septum assembly
JYB86_RS03940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JYB86_RS03945	COG2193	ferroxidase activity
JYB86_RS03950	COG2226	methyltransferase
JYB86_RS03950	COG0596	Alpha beta hydrolase
JYB86_RS03950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JYB86_RS03965	COG4106	trans-aconitate 2-methyltransferase activity
JYB86_RS03980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JYB86_RS03985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JYB86_RS04000	COG0009	L-threonylcarbamoyladenylate synthase
JYB86_RS04005	COG3101	peptidyl-lysine hydroxylation
JYB86_RS04010	COG1399	metal-binding, possibly nucleic acid-binding protein
JYB86_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS04035	COG1652	LysM domain
JYB86_RS04045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JYB86_RS04055	COG0745	RESPONSE REGULATOR receiver
JYB86_RS04060	COG2205	protein histidine kinase activity
JYB86_RS04065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JYB86_RS04080	COG1752	Esterase of the alpha-beta hydrolase superfamily
JYB86_RS04095	COG3338	carbonate dehydratase activity
JYB86_RS04100	COG1126	abc transporter atp-binding protein
JYB86_RS04105	COG0765	amino acid transport
JYB86_RS04110	COG0765	amino acid transport
JYB86_RS04120	COG2323	membrane
JYB86_RS04150	COG0525	valine-tRNA ligase activity
JYB86_RS04165	COG0393	Putative heavy-metal-binding
JYB86_RS04170	COG0393	Putative heavy-metal-binding
JYB86_RS04180	COG1538	Outer membrane efflux protein
JYB86_RS04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYB86_RS04195	COG0671	phosphoesterase, PA-phosphatase related
JYB86_RS04220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JYB86_RS04230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JYB86_RS04235	COG1648	precorrin-2 dehydrogenase activity
JYB86_RS04235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JYB86_RS04240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JYB86_RS04245	COG0531	amino acid
JYB86_RS04260	COG0321	lipoyl(octanoyl) transferase activity
JYB86_RS04295	COG0586	Pfam SNARE associated Golgi protein
JYB86_RS04335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYB86_RS04365	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JYB86_RS04380	COG0358	DNA primase activity
JYB86_RS04390	COG0564	pseudouridine synthase activity
JYB86_RS04405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JYB86_RS04415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JYB86_RS04445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JYB86_RS04445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYB86_RS04460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JYB86_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS04475	COG2072	flavoprotein involved in K transport
JYB86_RS04480	COG3385	transposase activity
JYB86_RS04495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JYB86_RS04500	COG1053	succinate dehydrogenase
JYB86_RS04505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JYB86_RS04520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JYB86_RS04530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JYB86_RS04540	COG0726	polysaccharide deacetylase
JYB86_RS04540	COG1649	PFAM Uncharacterised BCR, COG1649
JYB86_RS04545	COG1215	transferase activity, transferring glycosyl groups
JYB86_RS04555	COG2268	Band 7 protein
JYB86_RS04570	COG2354	Protein conserved in bacteria
JYB86_RS04575	COG2321	neutral zinc metallopeptidase
JYB86_RS04585	COG0589	response to stress
JYB86_RS04590	COG0110	maltose O-acetyltransferase activity
JYB86_RS04595	COG0415	Belongs to the DNA photolyase family
JYB86_RS04610	COG0505	Belongs to the CarA family
JYB86_RS04625	COG1534	Rna-binding protein
JYB86_RS04635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JYB86_RS04645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JYB86_RS04680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JYB86_RS04700	COG1597	lipid kinase activity
JYB86_RS04725	COG0584	glycerophosphoryl diester phosphodiesterase
JYB86_RS04735	COG2239	Acts as a magnesium transporter
JYB86_RS04745	COG0501	Belongs to the peptidase M48B family
JYB86_RS04750	COG1196	nuclear chromosome segregation
JYB86_RS04750	COG0741	lytic transglycosylase activity
JYB86_RS04750	COG0739	heme binding
JYB86_RS04755	COG0037	tRNA processing
JYB86_RS04765	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JYB86_RS04770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYB86_RS04790	COG1840	ABC-type Fe3 transport system, periplasmic component
JYB86_RS04795	COG3842	ATPase activity
JYB86_RS04800	COG1741	Belongs to the pirin family
JYB86_RS04810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JYB86_RS04815	COG3739	integral membrane protein
JYB86_RS04830	COG3706	GGDEF domain
JYB86_RS04840	COG0302	gtp cyclohydrolase
JYB86_RS04860	COG0512	Glutamine amidotransferase of anthranilate synthase
JYB86_RS04865	COG0174	glutamine synthetase
JYB86_RS04875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JYB86_RS04885	COG0583	DNA-binding transcription factor activity
JYB86_RS04920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JYB86_RS04925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JYB86_RS04945	COG1115	amino acid carrier protein
JYB86_RS04950	COG1113	amino acid transport
JYB86_RS04960	COG0019	diaminopimelate decarboxylase activity
JYB86_RS04975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JYB86_RS04985	COG1522	sequence-specific DNA binding
JYB86_RS04990	COG1280	lysine exporter protein (LysE YggA)
JYB86_RS05035	COG1671	Belongs to the UPF0178 family
JYB86_RS05050	COG4591	ABC-type transport system involved in lipoprotein release permease component
JYB86_RS05055	COG1136	(ABC) transporter
JYB86_RS05060	COG0658	competence protein
JYB86_RS05060	COG2333	competence protein COMEC
JYB86_RS05080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JYB86_RS05085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JYB86_RS05090	COG0628	permease
JYB86_RS05095	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYB86_RS05125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYB86_RS05145	COG0823	Involved in the tonB-independent uptake of proteins
JYB86_RS05165	COG0824	Thioesterase
JYB86_RS05175	COG2255	four-way junction helicase activity
JYB86_RS05205	COG1358	cellular component organization or biogenesis
JYB86_RS05235	COG2310	stress, protein
JYB86_RS05260	COG0047	phosphoribosylformylglycinamidine synthase activity
JYB86_RS05260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYB86_RS05275	COG0778	Nitroreductase
JYB86_RS05280	COG1024	Enoyl-CoA hydratase
JYB86_RS05285	COG1056	cytidyltransferase-related domain
JYB86_RS05285	COG1051	belongs to the nudix hydrolase family
JYB86_RS05290	COG2353	YceI-like domain
JYB86_RS05295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JYB86_RS05305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JYB86_RS05310	COG0602	queuosine metabolic process
JYB86_RS05330	COG0583	DNA-binding transcription factor activity
JYB86_RS05335	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JYB86_RS05340	COG4208	sulfate ABC transporter
JYB86_RS05355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JYB86_RS05365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JYB86_RS05380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JYB86_RS05390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYB86_RS05405	COG0681	Belongs to the peptidase S26 family
JYB86_RS05415	COG0571	ribonuclease III activity
JYB86_RS05420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JYB86_RS05430	COG1381	Involved in DNA repair and RecF pathway recombination
JYB86_RS05435	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JYB86_RS05460	COG0436	Aminotransferase
JYB86_RS05480	COG0556	nucleotide-excision repair
JYB86_RS05510	COG0702	epimerase
JYB86_RS05515	COG1733	regulation of RNA biosynthetic process
JYB86_RS05530	COG2814	Major facilitator Superfamily
JYB86_RS05540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JYB86_RS05550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JYB86_RS05555	COG0076	glutamate decarboxylase activity
JYB86_RS05570	COG0573	inorganic phosphate transmembrane transporter activity
JYB86_RS05580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYB86_RS05585	COG0616	signal peptide processing
JYB86_RS05640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JYB86_RS05645	COG1686	Belongs to the peptidase S11 family
JYB86_RS05660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JYB86_RS05670	COG0583	DNA-binding transcription factor activity
JYB86_RS05675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JYB86_RS05680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JYB86_RS05685	COG1067	ATP-dependent peptidase activity
JYB86_RS05720	COG1509	lysine 2,3-aminomutase activity
JYB86_RS05725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JYB86_RS05730	COG1966	Carbon starvation protein
JYB86_RS05735	COG2879	small protein
JYB86_RS05740	COG0714	Associated with various cellular activities
JYB86_RS05820	COG2252	PERMEase
JYB86_RS05825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JYB86_RS05835	COG1215	transferase activity, transferring glycosyl groups
JYB86_RS05845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYB86_RS05855	COG0527	aspartate kinase activity
JYB86_RS05865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JYB86_RS05880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JYB86_RS05885	COG0501	Belongs to the peptidase M48B family
JYB86_RS05900	COG0667	Aldo Keto reductase
JYB86_RS05910	COG1765	OsmC-like protein
JYB86_RS05935	COG0540	Belongs to the ATCase OTCase family
JYB86_RS05950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JYB86_RS05965	COG4770	biotin carboxylase activity
JYB86_RS05970	COG1024	Enoyl-CoA hydratase
JYB86_RS05975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JYB86_RS05980	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS05985	COG1309	transcriptional regulator
JYB86_RS05990	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS06010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JYB86_RS06020	COG0659	secondary active sulfate transmembrane transporter activity
JYB86_RS06030	COG3385	transposase activity
JYB86_RS06045	COG2363	Small membrane protein
JYB86_RS06065	COG0513	Belongs to the DEAD box helicase family
JYB86_RS06130	COG4783	chaperone-mediated protein folding
JYB86_RS06145	COG1610	YqeY-like protein
JYB86_RS06175	COG2815	serine threonine protein kinase
JYB86_RS06175	COG0515	serine threonine protein kinase
JYB86_RS06215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JYB86_RS06215	COG2755	lipolytic protein G-D-S-L family
JYB86_RS06220	COG0436	Aminotransferase
JYB86_RS06225	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JYB86_RS06230	COG0386	Belongs to the glutathione peroxidase family
JYB86_RS06240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JYB86_RS06255	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JYB86_RS06265	COG0012	GTP binding
JYB86_RS06290	COG0204	Acyl-transferase
JYB86_RS06340	COG1373	ATPase (AAA superfamily
JYB86_RS06375	COG0514	ATP-dependent DNA helicase (RecQ)
JYB86_RS06400	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JYB86_RS06400	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JYB86_RS06405	COG4372	Transposase
JYB86_RS06460	COG4372	Transposase
JYB86_RS06470	COG0582	viral genome integration into host DNA
JYB86_RS06485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYB86_RS06495	COG1136	(ABC) transporter
JYB86_RS06515	COG2351	hydroxyisourate hydrolase activity
JYB86_RS06530	COG3046	protein related to deoxyribodipyrimidine photolyase
JYB86_RS06535	COG2816	NAD+ diphosphatase activity
JYB86_RS06560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JYB86_RS06575	COG0642	Histidine kinase
JYB86_RS06610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JYB86_RS06675	COG4773	Receptor
JYB86_RS06695	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JYB86_RS06705	COG5002	protein histidine kinase activity
JYB86_RS06705	COG5001	Diguanylate cyclase
JYB86_RS06725	COG4372	Transposase
JYB86_RS06740	COG0783	Belongs to the Dps family
JYB86_RS06745	COG2814	Major facilitator Superfamily
JYB86_RS06750	COG1012	belongs to the aldehyde dehydrogenase family
JYB86_RS06750	COG2030	dehydratase
JYB86_RS06755	COG3396	Phenylacetate-CoA oxygenase
JYB86_RS06760	COG3460	Phenylacetate-CoA oxygenase
JYB86_RS06765	COG3396	Phenylacetate-CoA oxygenase
JYB86_RS06770	COG2151	metal-sulfur cluster biosynthetic enzyme
JYB86_RS06775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JYB86_RS06780	COG1024	Enoyl-CoA hydratase
JYB86_RS06785	COG1024	Enoyl-CoA hydratase
JYB86_RS06790	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYB86_RS06795	COG0183	Belongs to the thiolase family
JYB86_RS06800	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JYB86_RS06805	COG3327	negative regulation of DNA-templated transcription, initiation
JYB86_RS06815	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS06835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JYB86_RS06840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JYB86_RS06840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JYB86_RS06845	COG1254	Belongs to the acylphosphatase family
JYB86_RS06880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JYB86_RS06885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JYB86_RS06895	COG2353	YceI-like domain
JYB86_RS06900	COG3385	transposase activity
JYB86_RS06905	COG0519	Catalyzes the synthesis of GMP from XMP
JYB86_RS06905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JYB86_RS06935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JYB86_RS06940	COG0583	DNA-binding transcription factor activity
JYB86_RS06950	COG2707	UPF0756 membrane protein
JYB86_RS06975	COG0802	atpase or kinase
JYB86_RS06980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JYB86_RS06990	COG1923	regulation of RNA biosynthetic process
JYB86_RS06995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JYB86_RS07005	COG3178	'Phosphotransferase
JYB86_RS07010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JYB86_RS07020	COG1192	Involved in chromosome partitioning
JYB86_RS07025	COG1475	DNA binding
JYB86_RS07030	COG0811	peptide transport
JYB86_RS07040	COG1132	(ABC) transporter
JYB86_RS07045	COG1663	tetraacyldisaccharide 4'-kinase activity
JYB86_RS07065	COG0084	hydrolase, TatD family'
JYB86_RS07100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JYB86_RS07130	COG0776	regulation of translation
JYB86_RS07140	COG0284	orotidine-5'-phosphate decarboxylase activity
JYB86_RS07150	COG2431	L-lysine efflux transmembrane transporter activity
JYB86_RS07165	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JYB86_RS07170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JYB86_RS07190	COG1253	flavin adenine dinucleotide binding
JYB86_RS07220	COG0583	DNA-binding transcription factor activity
JYB86_RS07235	COG3852	Histidine kinase
JYB86_RS07250	COG0233	cytoplasmic translational termination
JYB86_RS07255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JYB86_RS07260	COG0575	Belongs to the CDS family
JYB86_RS07295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JYB86_RS07325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JYB86_RS07330	COG0730	response to heat
JYB86_RS07335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JYB86_RS07340	COG2207	Transcriptional regulator
JYB86_RS07345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JYB86_RS07355	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS07360	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS07395	COG4890	Cyd operon protein YbgT
JYB86_RS07400	COG1294	oxidase, subunit
JYB86_RS07415	COG1585	Membrane protein implicated in regulation of membrane protease activity
JYB86_RS07425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYB86_RS07445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JYB86_RS07450	COG0569	domain protein
JYB86_RS07460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JYB86_RS07480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JYB86_RS07485	COG0542	response to heat
JYB86_RS07520	COG0372	Belongs to the citrate synthase family
JYB86_RS07530	COG1546	Belongs to the CinA family
JYB86_RS07530	COG1058	Belongs to the CinA family
JYB86_RS07565	COG3038	cytochrome b561
JYB86_RS07570	COG2814	Major facilitator Superfamily
JYB86_RS07585	COG0439	Biotin carboxylase
JYB86_RS07590	COG0511	ligase activity, forming carbon-carbon bonds
JYB86_RS07625	COG0596	Alpha beta hydrolase
JYB86_RS07750	COG0730	response to heat
JYB86_RS07755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JYB86_RS07760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JYB86_RS07770	COG2885	chlorophyll binding
JYB86_RS07790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JYB86_RS07820	COG1012	belongs to the aldehyde dehydrogenase family
JYB86_RS07825	COG1309	transcriptional regulator
JYB86_RS07830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JYB86_RS07860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JYB86_RS07890	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS07900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JYB86_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS07910	COG1846	Transcriptional regulator
JYB86_RS07915	COG2814	Major facilitator Superfamily
JYB86_RS07930	COG0318	PFAM AMP-dependent synthetase and ligase
JYB86_RS07945	COG2226	methyltransferase
JYB86_RS07945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JYB86_RS07945	COG0596	Alpha beta hydrolase
JYB86_RS07950	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS07960	COG1024	Enoyl-CoA hydratase
JYB86_RS07965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JYB86_RS07970	COG0235	Class ii aldolase
JYB86_RS07980	COG0183	Belongs to the thiolase family
JYB86_RS07985	COG1250	3-hydroxyacyl-CoA dehydrogenase
JYB86_RS07990	COG1024	Enoyl-CoA hydratase
JYB86_RS07995	COG2814	Major facilitator Superfamily
JYB86_RS08005	COG2814	Major facilitator Superfamily
JYB86_RS08010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JYB86_RS08015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JYB86_RS08020	COG2814	Major facilitator Superfamily
JYB86_RS08025	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS08030	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS08040	COG0644	oxidoreductase
JYB86_RS08040	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
JYB86_RS08045	COG0515	serine threonine protein kinase
JYB86_RS08050	COG2116	formate transmembrane transporter activity
JYB86_RS08065	COG2223	nitrite transmembrane transporter activity
JYB86_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS08105	COG2814	Major facilitator Superfamily
JYB86_RS08110	COG0583	DNA-binding transcription factor activity
JYB86_RS08115	COG4948	Mandelate Racemase Muconate Lactonizing
JYB86_RS08120	COG4829	muconolactone delta-isomerase
JYB86_RS08130	COG4638	Rieske (2fe-2S)
JYB86_RS08135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JYB86_RS08140	COG0633	Ferredoxin
JYB86_RS08140	COG0543	2 iron, 2 sulfur cluster binding
JYB86_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS08150	COG3135	benzoate transporter
JYB86_RS08155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JYB86_RS08160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JYB86_RS08165	COG0183	Belongs to the thiolase family
JYB86_RS08170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JYB86_RS08190	COG0583	DNA-binding transcription factor activity
JYB86_RS08195	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JYB86_RS08200	COG4149	molybdate abc transporter
JYB86_RS08205	COG0725	ABC transporter, periplasmic molybdate-binding protein
JYB86_RS08210	COG0303	'Molybdopterin
JYB86_RS08215	COG0315	cyclic pyranopterin monophosphate synthase activity
JYB86_RS08215	COG0521	Mo-molybdopterin cofactor biosynthetic process
JYB86_RS08230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYB86_RS08240	COG0243	molybdopterin cofactor binding
JYB86_RS08245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYB86_RS08250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYB86_RS08255	COG2223	nitrite transmembrane transporter activity
JYB86_RS08265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JYB86_RS08265	COG1116	anion transmembrane transporter activity
JYB86_RS08270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYB86_RS08275	COG2937	Belongs to the GPAT DAPAT family
JYB86_RS08280	COG0640	Transcriptional regulator
JYB86_RS08300	COG3122	Protein conserved in bacteria
JYB86_RS08305	COG0668	transmembrane transport
JYB86_RS08320	COG1132	(ABC) transporter
JYB86_RS08340	COG2814	Major facilitator Superfamily
JYB86_RS08350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JYB86_RS08360	COG1113	amino acid transport
JYB86_RS08375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JYB86_RS08380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JYB86_RS08430	COG1525	nuclease
JYB86_RS08440	COG1294	oxidase, subunit
JYB86_RS08445	COG1271	oxidase subunit
JYB86_RS08455	COG2814	Major facilitator Superfamily
JYB86_RS08460	COG2207	Transcriptional regulator
JYB86_RS08465	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS08500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JYB86_RS08505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JYB86_RS08525	COG0583	DNA-binding transcription factor activity
JYB86_RS08535	COG1346	cytolysis
JYB86_RS08545	COG1283	sodium-dependent phosphate transmembrane transporter activity
JYB86_RS08555	COG0693	protein deglycase activity
JYB86_RS08600	COG0552	protein localization to endoplasmic reticulum
JYB86_RS08605	COG0612	Peptidase, M16
JYB86_RS08630	COG0617	tRNA 3'-terminal CCA addition
JYB86_RS08630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JYB86_RS08630	COG0517	IMP dehydrogenase activity
JYB86_RS08635	COG0133	tryptophan synthase activity
JYB86_RS08645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JYB86_RS08665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JYB86_RS08720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JYB86_RS08750	COG0822	iron-sulfur transferase activity
JYB86_RS08755	COG0316	Belongs to the HesB IscA family
JYB86_RS08785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JYB86_RS08800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JYB86_RS08805	COG0702	epimerase
JYB86_RS08810	COG0268	Binds directly to 16S ribosomal RNA
JYB86_RS08830	COG1011	Hydrolase
JYB86_RS08835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JYB86_RS08845	COG2137	regulation of response to DNA damage stimulus
JYB86_RS08860	COG0772	Belongs to the SEDS family
JYB86_RS08875	COG0148	phosphopyruvate hydratase activity
JYB86_RS08905	COG1902	pentaerythritol trinitrate reductase activity
JYB86_RS08905	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYB86_RS08925	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS08930	COG0583	DNA-binding transcription factor activity
JYB86_RS08935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JYB86_RS08940	COG1027	Aspartate ammonia-lyase
JYB86_RS08945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JYB86_RS08960	COG0506	proline dehydrogenase activity
JYB86_RS08960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JYB86_RS08960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JYB86_RS08980	COG3698	Phosphodiester glycosidase
JYB86_RS09020	COG0697	spore germination
JYB86_RS09025	COG3385	transposase activity
JYB86_RS09050	COG0424	maF-like protein
JYB86_RS09055	COG2850	peptidyl-arginine hydroxylation
JYB86_RS09060	COG4585	Histidine kinase
JYB86_RS09070	COG0069	glutamate synthase activity
JYB86_RS09090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JYB86_RS09095	COG1454	alcohol dehydrogenase
JYB86_RS09100	COG0824	Thioesterase
JYB86_RS09105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JYB86_RS09115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JYB86_RS09120	COG2030	dehydratase
JYB86_RS09130	COG0183	Belongs to the thiolase family
JYB86_RS09145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JYB86_RS09155	COG3135	benzoate transporter
JYB86_RS09165	COG0589	response to stress
JYB86_RS09170	COG0589	response to stress
JYB86_RS09180	COG0308	aminopeptidase N
JYB86_RS09210	COG0786	glutamate:sodium symporter activity
JYB86_RS09250	COG0477	Major facilitator Superfamily
JYB86_RS09265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JYB86_RS09275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYB86_RS09290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JYB86_RS09295	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS09315	COG3781	membrane
JYB86_RS09325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JYB86_RS09345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JYB86_RS09370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JYB86_RS09375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JYB86_RS09380	COG1845	cytochrome c oxidase, subunit III
JYB86_RS09385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JYB86_RS09395	COG0360	Binds together with S18 to 16S ribosomal RNA
JYB86_RS09400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JYB86_RS09415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JYB86_RS09430	COG1305	Transglutaminase-like
JYB86_RS09440	COG2308	Evidence 4 Homologs of previously reported genes of
JYB86_RS09480	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JYB86_RS09485	COG0138	bifunctional purine biosynthesis protein purh
JYB86_RS09505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JYB86_RS09510	COG2011	ABC-type metal ion transport system permease component
JYB86_RS09540	COG1454	alcohol dehydrogenase
JYB86_RS09555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JYB86_RS09565	COG4122	O-methyltransferase activity
JYB86_RS09590	COG2274	protein secretion by the type I secretion system
JYB86_RS09600	COG1137	ATPase activity
JYB86_RS09605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JYB86_RS09615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JYB86_RS09620	COG0517	IMP dehydrogenase activity
JYB86_RS09620	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JYB86_RS09645	COG1643	Atp-dependent helicase
JYB86_RS09675	COG3634	alkyl hydroperoxide reductase activity
JYB86_RS09685	COG3293	Transposase
JYB86_RS09690	COG2391	methyltransferase activity
JYB86_RS09715	COG2070	2-Nitropropane dioxygenase
JYB86_RS09730	COG1278	Cold shock
JYB86_RS09790	COG1309	transcriptional regulator
JYB86_RS09795	COG0596	Alpha beta hydrolase
JYB86_RS09835	COG0352	thiamine-phosphate diphosphorylase activity
JYB86_RS09870	COG0612	Peptidase, M16
JYB86_RS09880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JYB86_RS09890	COG0739	heme binding
JYB86_RS09905	COG1187	pseudouridine synthase activity
JYB86_RS09920	COG1686	Belongs to the peptidase S11 family
JYB86_RS09925	COG1252	NADH dehydrogenase
JYB86_RS09930	COG1047	Peptidyl-prolyl cis-trans
JYB86_RS09955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JYB86_RS09960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JYB86_RS09970	COG0693	protein deglycase activity
JYB86_RS09975	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS09980	COG1301	dicarboxylic acid transport
JYB86_RS09990	COG3139	Protein of unknown function (DUF1315)
JYB86_RS09995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JYB86_RS10000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYB86_RS10035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JYB86_RS10045	COG1720	tRNA m6t6A37 methyltransferase activity
JYB86_RS10060	COG0789	Transcriptional regulator
JYB86_RS10065	COG0431	NADPH-dependent FMN reductase
JYB86_RS10070	COG0798	PFAM Bile acid sodium symporter
JYB86_RS10080	COG0640	Transcriptional regulator
JYB86_RS10090	COG0826	peptidase U32
JYB86_RS10095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JYB86_RS10100	COG3634	alkyl hydroperoxide reductase activity
JYB86_RS10120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYB86_RS10175	COG1131	(ABC) transporter
JYB86_RS10180	COG0842	Transport permease protein
JYB86_RS10195	COG2951	lytic endotransglycosylase activity
JYB86_RS10220	COG0052	Belongs to the universal ribosomal protein uS2 family
JYB86_RS10240	COG2175	clavaminate synthase activity
JYB86_RS10250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JYB86_RS10255	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS10280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JYB86_RS10285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JYB86_RS10290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JYB86_RS10310	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JYB86_RS10340	COG2871	sodium ion transport
JYB86_RS10350	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYB86_RS10350	COG1902	pentaerythritol trinitrate reductase activity
JYB86_RS10370	COG4251	negative regulation of phosphorylation
JYB86_RS10370	COG2203	Gaf domain
JYB86_RS10370	COG3706	GGDEF domain
JYB86_RS10370	COG5001	Diguanylate cyclase
JYB86_RS10375	COG0418	dihydroorotase activity
JYB86_RS10380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JYB86_RS10405	COG0833	amino acid
JYB86_RS10435	COG4172	Belongs to the ABC transporter superfamily
JYB86_RS10440	COG4239	(ABC) transporter, permease
JYB86_RS10445	COG4174	ABC transporter (Permease)
JYB86_RS10450	COG4166	transmembrane transport
JYB86_RS10455	COG1388	LysM domain
JYB86_RS10455	COG0741	lytic transglycosylase activity
JYB86_RS10470	COG2816	NAD+ diphosphatase activity
JYB86_RS10505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JYB86_RS10510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JYB86_RS10520	COG0006	proline dipeptidase activity
JYB86_RS10525	COG3079	Belongs to the UPF0149 family
JYB86_RS10555	COG0277	FAD linked oxidase domain protein
JYB86_RS10565	COG2186	Transcriptional regulator
JYB86_RS10585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JYB86_RS10595	COG2234	aminopeptidase activity
JYB86_RS10605	COG3384	dioxygenase
JYB86_RS10615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JYB86_RS10620	COG2878	Part of a membrane complex involved in electron transport
JYB86_RS10625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JYB86_RS10650	COG0768	penicillin binding
JYB86_RS10655	COG0742	ribosomal rna small subunit methyltransferase
JYB86_RS10670	COG0830	nickel cation binding
JYB86_RS10700	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS10715	COG3015	lipoprotein NlpE involved in copper resistance
JYB86_RS10735	COG1253	flavin adenine dinucleotide binding
JYB86_RS10760	COG3118	belongs to the thioredoxin family
JYB86_RS10795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYB86_RS10800	COG1773	rubredoxin
JYB86_RS10805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JYB86_RS10815	COG0583	DNA-binding transcription factor activity
JYB86_RS10825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYB86_RS10835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JYB86_RS10840	COG4181	ATPase activity
JYB86_RS10865	COG4771	TonB-dependent receptor
JYB86_RS10890	COG0306	phosphate transporter
JYB86_RS10905	COG4372	Transposase
JYB86_RS10940	COG2852	Protein conserved in bacteria
JYB86_RS10950	COG2376	Dihydroxyacetone kinase
JYB86_RS10955	COG2066	Belongs to the glutaminase family
JYB86_RS10965	COG0477	Major facilitator Superfamily
JYB86_RS10995	COG2199	diguanylate cyclase activity
JYB86_RS10995	COG2203	Gaf domain
JYB86_RS11005	COG4681	YaeQ
JYB86_RS11010	COG0523	cobalamin synthesis protein
JYB86_RS11030	COG0583	DNA-binding transcription factor activity
JYB86_RS11035	COG2814	Major facilitator Superfamily
JYB86_RS11045	COG1607	acyl-coa hydrolase
JYB86_RS11055	COG1752	Esterase of the alpha-beta hydrolase superfamily
JYB86_RS11060	COG2059	Chromate
JYB86_RS11065	COG1115	amino acid carrier protein
JYB86_RS11070	COG0786	glutamate:sodium symporter activity
JYB86_RS11085	COG2814	Major facilitator Superfamily
JYB86_RS11090	COG1289	transmembrane transporter activity
JYB86_RS11100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JYB86_RS11155	COG1376	ErfK ybiS ycfS ynhG family protein
JYB86_RS11160	COG2832	Protein of unknown function (DUF454)
JYB86_RS11170	COG5510	response to toxic substance
JYB86_RS11185	COG2198	Histidine kinase
JYB86_RS11185	COG0784	Response regulator, receiver
JYB86_RS11185	COG0643	Histidine kinase
JYB86_RS11190	COG0840	transmembrane signaling receptor activity
JYB86_RS11225	COG0442	prolyl-tRNA aminoacylation
JYB86_RS11260	COG2358	TRAP transporter, solute receptor (TAXI family
JYB86_RS11275	COG0489	protein tyrosine kinase activity
JYB86_RS11280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYB86_RS11280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYB86_RS11305	COG0004	ammonium transporteR
JYB86_RS11320	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JYB86_RS11335	COG2081	HI0933 family
JYB86_RS11350	COG0668	transmembrane transport
JYB86_RS11375	COG0583	DNA-binding transcription factor activity
JYB86_RS11385	COG1278	Cold shock
JYB86_RS11400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYB86_RS11405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JYB86_RS11410	COG0713	ATP synthesis coupled electron transport
JYB86_RS11415	COG0839	Belongs to the complex I subunit 6 family
JYB86_RS11420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYB86_RS11425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JYB86_RS11435	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JYB86_RS11455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYB86_RS11465	COG0142	geranyltranstransferase activity
JYB86_RS11470	COG2828	Protein conserved in bacteria
JYB86_RS11475	COG1113	amino acid transport
JYB86_RS11495	COG0625	glutathione transferase activity
JYB86_RS11535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JYB86_RS11545	COG1530	ribonuclease E activity
JYB86_RS11550	COG0424	maF-like protein
JYB86_RS11555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JYB86_RS11560	COG1792	Involved in formation and maintenance of cell shape
JYB86_RS11565	COG1077	Cell shape determining protein MreB Mrl
JYB86_RS11570	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYB86_RS11575	COG0154	amidase activity
JYB86_RS11580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYB86_RS11615	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
JYB86_RS11630	COG1215	transferase activity, transferring glycosyl groups
JYB86_RS11635	COG0726	polysaccharide deacetylase
JYB86_RS11635	COG1649	PFAM Uncharacterised BCR, COG1649
JYB86_RS11665	COG3177	Filamentation induced by cAMP protein fic
JYB86_RS11690	COG3586	endonuclease activity
JYB86_RS11775	COG0582	viral genome integration into host DNA
JYB86_RS11785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JYB86_RS11790	COG2050	protein possibly involved in aromatic compounds catabolism
JYB86_RS11810	COG0420	3'-5' exonuclease activity
JYB86_RS11840	COG0735	belongs to the Fur family
JYB86_RS11845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JYB86_RS11850	COG3385	transposase activity
JYB86_RS11855	COG2914	Belongs to the UPF0125 (RnfH) family
JYB86_RS11870	COG0121	glutamine amidotransferase
JYB86_RS11880	COG4372	Transposase
JYB86_RS11905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYB86_RS11915	COG0210	DNA helicase
JYB86_RS11920	COG2885	chlorophyll binding
JYB86_RS11925	COG0204	Acyl-transferase
JYB86_RS11935	COG0850	regulation of cytokinetic process
JYB86_RS11940	COG2894	cell division
JYB86_RS11955	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JYB86_RS11955	COG1674	ftsk spoiiie
JYB86_RS11960	COG0492	ferredoxin-NADP+ reductase activity
JYB86_RS11965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JYB86_RS11975	COG0456	acetyltransferase
JYB86_RS12000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JYB86_RS12015	COG1981	membrane
JYB86_RS12020	COG1113	amino acid transport
JYB86_RS12025	COG0251	oxidation-reduction process
JYB86_RS12050	COG0351	phosphomethylpyrimidine kinase
JYB86_RS12050	COG0352	thiamine-phosphate diphosphorylase activity
JYB86_RS12050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JYB86_RS12065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JYB86_RS12070	COG2076	Multidrug Resistance protein
JYB86_RS12080	COG2132	Multicopper oxidase
JYB86_RS12090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JYB86_RS12105	COG4269	membrane
JYB86_RS12125	COG1968	undecaprenyl-diphosphatase activity
JYB86_RS12130	COG1214	PFAM Peptidase M22, glycoprotease
JYB86_RS12140	COG0494	nUDIX hydrolase
JYB86_RS12190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JYB86_RS12195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JYB86_RS12285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JYB86_RS12290	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JYB86_RS12305	COG0450	alkyl hydroperoxide reductase
JYB86_RS12320	COG0285	dihydrofolate synthase activity
JYB86_RS12325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JYB86_RS12370	COG4206	TonB-dependent receptor
JYB86_RS12375	COG2096	Adenosyltransferase
JYB86_RS12395	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JYB86_RS12400	COG2315	Protein conserved in bacteria
JYB86_RS12405	COG0745	RESPONSE REGULATOR receiver
JYB86_RS12410	COG2205	protein histidine kinase activity
JYB86_RS12420	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS12425	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS12430	COG3223	Belongs to the PsiE family
JYB86_RS12465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JYB86_RS12480	COG0438	transferase activity, transferring glycosyl groups
JYB86_RS12495	COG0463	Glycosyl transferase, family 2
JYB86_RS12515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JYB86_RS12520	COG5002	protein histidine kinase activity
JYB86_RS12535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JYB86_RS12545	COG1704	LemA family
JYB86_RS12550	COG4251	negative regulation of phosphorylation
JYB86_RS12550	COG2203	Gaf domain
JYB86_RS12550	COG5001	Diguanylate cyclase
JYB86_RS12550	COG3706	GGDEF domain
JYB86_RS12560	COG1862	Preprotein translocase
JYB86_RS12580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYB86_RS12595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYB86_RS12600	COG5002	protein histidine kinase activity
JYB86_RS12600	COG0784	Response regulator, receiver
JYB86_RS12600	COG2205	protein histidine kinase activity
JYB86_RS12605	COG1024	Enoyl-CoA hydratase
JYB86_RS12615	COG3622	Belongs to the hyi family
JYB86_RS12640	COG0697	spore germination
JYB86_RS12645	COG2814	Major facilitator Superfamily
JYB86_RS12665	COG1058	Belongs to the CinA family
JYB86_RS12665	COG1546	Belongs to the CinA family
JYB86_RS12690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JYB86_RS12695	COG3385	transposase activity
JYB86_RS12700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JYB86_RS12705	COG0084	hydrolase, TatD family'
JYB86_RS12720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JYB86_RS12735	COG0793	Belongs to the peptidase S41A family
JYB86_RS12765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JYB86_RS12770	COG0857	belongs to the CobB CobQ family
JYB86_RS12770	COG0280	phosphate acetyltransferase
JYB86_RS12780	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JYB86_RS12780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JYB86_RS12795	COG0740	serine-type endopeptidase activity
JYB86_RS12805	COG4771	TonB-dependent receptor
JYB86_RS12810	COG4774	siderophore transport
JYB86_RS12815	COG3128	pkhd-type hydroxylase
JYB86_RS12825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JYB86_RS12830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JYB86_RS12835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JYB86_RS12835	COG2813	Specifically methylates the guanine in position
JYB86_RS12895	COG3040	lipid binding
JYB86_RS12925	COG0179	Fumarylacetoacetate (FAA) hydrolase
JYB86_RS12960	COG0557	exoribonuclease II activity
JYB86_RS12970	COG0339	signal peptide processing
JYB86_RS12975	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JYB86_RS12985	COG0697	spore germination
JYB86_RS12990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JYB86_RS13015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JYB86_RS13020	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS13025	COG2072	flavoprotein involved in K transport
JYB86_RS13035	COG0202	RNA polymerase activity
JYB86_RS13040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JYB86_RS13075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JYB86_RS13085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JYB86_RS13090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JYB86_RS13125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JYB86_RS13155	COG0088	Forms part of the polypeptide exit tunnel
JYB86_RS13185	COG0433	COG0433 Predicted ATPase
JYB86_RS13195	COG1959	2 iron, 2 sulfur cluster binding
JYB86_RS13215	COG1301	dicarboxylic acid transport
JYB86_RS13220	COG1946	Acyl-CoA thioesterase
JYB86_RS13225	COG2937	Belongs to the GPAT DAPAT family
JYB86_RS13235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JYB86_RS13240	COG1040	competence protein
JYB86_RS13255	COG0598	Magnesium transport protein CorA
JYB86_RS13265	COG2854	intermembrane phospholipid transfer
JYB86_RS13270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JYB86_RS13275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JYB86_RS13280	COG1127	ABC transporter
JYB86_RS13305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JYB86_RS13310	COG0408	coproporphyrinogen oxidase activity
JYB86_RS13325	COG1960	acyl-CoA dehydrogenase activity
JYB86_RS13330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JYB86_RS13340	COG0534	Mate efflux family protein
JYB86_RS13345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JYB86_RS13350	COG0254	rRNA binding
JYB86_RS13355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JYB86_RS13375	COG2226	methyltransferase
JYB86_RS13390	COG1192	Involved in chromosome partitioning
JYB86_RS13395	COG0628	permease
JYB86_RS13405	COG2814	Major facilitator Superfamily
JYB86_RS13420	COG0277	FAD linked oxidase domain protein
JYB86_RS13425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JYB86_RS13450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JYB86_RS13455	COG5380	lipid catabolic process
JYB86_RS13480	COG0335	large ribosomal subunit rRNA binding
JYB86_RS13490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JYB86_RS13495	COG0228	four-way junction DNA binding
JYB86_RS13540	COG0194	GDP metabolic process
JYB86_RS13545	COG1758	RNA polymerase activity
JYB86_RS13550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYB86_RS13580	COG3609	addiction module antidote protein, CC2985 family
JYB86_RS13585	COG3307	-O-antigen
JYB86_RS13605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JYB86_RS13610	COG1704	LemA family
JYB86_RS13620	COG0493	'glutamate synthase
JYB86_RS13625	COG0070	glutamate synthase
JYB86_RS13625	COG0067	glutamate synthase
JYB86_RS13625	COG0069	glutamate synthase activity
JYB86_RS13675	COG3385	transposase activity
JYB86_RS13680	COG2226	methyltransferase
JYB86_RS13690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JYB86_RS13695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JYB86_RS13710	COG0275	rRNA processing
JYB86_RS13715	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JYB86_RS13725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYB86_RS13755	COG0488	(ABC) transporter
JYB86_RS13765	COG4221	oxidoreductase activity
JYB86_RS13775	COG3385	transposase activity
JYB86_RS13795	COG0427	acetyl-CoA hydrolase
JYB86_RS13825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JYB86_RS13850	COG0697	spore germination
JYB86_RS13865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JYB86_RS13905	COG3158	transport of potassium into the cell
JYB86_RS13965	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JYB86_RS13985	COG2801	Transposase and inactivated derivatives
JYB86_RS14000	COG3077	Addiction module antitoxin, RelB DinJ family
JYB86_RS14020	COG4372	Transposase
JYB86_RS14040	COG2132	Multicopper oxidase
JYB86_RS14045	COG2801	Transposase and inactivated derivatives
JYB86_RS14085	COG3077	Addiction module antitoxin, RelB DinJ family
JYB86_RS14090	COG2801	Transposase and inactivated derivatives
JYB86_RS14105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JYB86_RS14170	COG0629	single-stranded DNA binding
JYB86_RS14175	COG2814	Major facilitator Superfamily
JYB86_RS14185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JYB86_RS14190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JYB86_RS14205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JYB86_RS14225	COG3385	transposase activity
JYB86_RS14230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JYB86_RS14235	COG3162	membrane
JYB86_RS14240	COG2205	protein histidine kinase activity
JYB86_RS14240	COG0784	Response regulator, receiver
JYB86_RS14255	COG0431	NADPH-dependent FMN reductase
JYB86_RS14265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JYB86_RS14270	COG0668	transmembrane transport
JYB86_RS14275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JYB86_RS14280	COG1519	Transferase
JYB86_RS14285	COG1902	pentaerythritol trinitrate reductase activity
JYB86_RS14310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JYB86_RS14335	COG0426	domain, Protein
JYB86_RS14335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JYB86_RS14340	COG2119	membrane
JYB86_RS14370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JYB86_RS14380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JYB86_RS14390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYB86_RS14400	COG0189	ligase activity
JYB86_RS14410	COG4115	mRNA cleavage
JYB86_RS14455	COG0708	Exodeoxyribonuclease III
JYB86_RS14460	COG1393	Belongs to the ArsC family
JYB86_RS14475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JYB86_RS14505	COG0625	glutathione transferase activity
JYB86_RS14550	COG1247	-acetyltransferase
JYB86_RS14555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JYB86_RS14560	COG4266	Belongs to the allantoicase family
JYB86_RS14565	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JYB86_RS14580	COG0471	metal ion transport
JYB86_RS14625	COG3150	esterase
JYB86_RS14635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JYB86_RS14640	COG2918	glutathione biosynthetic process
JYB86_RS14655	COG2733	membrane
JYB86_RS14660	COG0436	Aminotransferase
JYB86_RS14665	COG0534	Mate efflux family protein
JYB86_RS14710	COG0753	catalase activity
JYB86_RS14730	COG3830	Belongs to the UPF0237 family
JYB86_RS14730	COG0560	Phosphoserine phosphatase
JYB86_RS14745	COG0385	Bile acid
JYB86_RS14750	COG1335	isochorismatase
JYB86_RS14755	COG2814	Major facilitator Superfamily
JYB86_RS14760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JYB86_RS14770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JYB86_RS14775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYB86_RS14780	COG2983	Belongs to the UPF0260 family
JYB86_RS14785	COG5487	UPF0391 membrane protein
JYB86_RS14800	COG1194	a g-specific adenine glycosylase
JYB86_RS14805	COG0739	heme binding
JYB86_RS14815	COG2818	Glycosylase
JYB86_RS14820	COG1064	alcohol dehydrogenase
JYB86_RS14840	COG3023	N-Acetylmuramoyl-L-alanine amidase
JYB86_RS14850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JYB86_RS14855	COG1309	transcriptional regulator
JYB86_RS14865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JYB86_RS14870	COG0546	phosphoglycolate phosphatase activity
JYB86_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
JYB86_RS14900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JYB86_RS14900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JYB86_RS14905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JYB86_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JYB86_RS14915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JYB86_RS14920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JYB86_RS14925	COG1116	anion transmembrane transporter activity
JYB86_RS14935	COG0675	Transposase, IS605 OrfB family
JYB86_RS14940	COG1309	transcriptional regulator
JYB86_RS14950	COG0196	riboflavin kinase activity
JYB86_RS14955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JYB86_RS14960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JYB86_RS14965	COG1047	Peptidyl-prolyl cis-trans
JYB86_RS14975	COG2133	pyrroloquinoline quinone binding
JYB86_RS14980	COG2814	Major facilitator Superfamily
JYB86_RS15010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JYB86_RS15020	COG0657	acetylesterase activity
JYB86_RS15060	COG2951	lytic endotransglycosylase activity
JYB86_RS15075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JYB86_RS15095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYB86_RS15105	COG2388	GCN5-related N-acetyl-transferase
JYB86_RS15115	COG0861	Integral membrane protein TerC family
JYB86_RS15120	COG0402	S-adenosylhomocysteine deaminase activity
JYB86_RS15140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JYB86_RS15145	COG1230	cation diffusion facilitator family transporter
JYB86_RS15165	COG0675	Transposase, IS605 OrfB family
JYB86_RS15195	COG0706	membrane insertase activity
JYB86_RS15200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JYB86_RS15205	COG0594	ribonuclease P activity