locus-tag	class	description
FSC05_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC05_RS00010	COG0592	DNA-directed DNA polymerase activity
FSC05_RS00020	COG0187	DNA topoisomerase II activity
FSC05_RS00040	COG0488	(ABC) transporter
FSC05_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FSC05_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSC05_RS00080	COG0737	Belongs to the 5'-nucleotidase family
FSC05_RS00110	COG2814	Major facilitator Superfamily
FSC05_RS00115	COG2133	pyrroloquinoline quinone binding
FSC05_RS00135	COG1047	Peptidyl-prolyl cis-trans
FSC05_RS00140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSC05_RS00145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSC05_RS00150	COG0196	riboflavin kinase activity
FSC05_RS00160	COG1309	transcriptional regulator
FSC05_RS00165	COG0675	Transposase, IS605 OrfB family
FSC05_RS00175	COG1116	anion transmembrane transporter activity
FSC05_RS00180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC05_RS00185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC05_RS00190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC05_RS00195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC05_RS00200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSC05_RS00200	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FSC05_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_RS00225	COG0546	phosphoglycolate phosphatase activity
FSC05_RS00230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC05_RS00240	COG1309	transcriptional regulator
FSC05_RS00245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSC05_RS00255	COG3023	N-Acetylmuramoyl-L-alanine amidase
FSC05_RS00275	COG1064	alcohol dehydrogenase
FSC05_RS00280	COG2818	Glycosylase
FSC05_RS00290	COG0739	heme binding
FSC05_RS00295	COG1194	a g-specific adenine glycosylase
FSC05_RS00310	COG5487	UPF0391 membrane protein
FSC05_RS00315	COG2983	Belongs to the UPF0260 family
FSC05_RS00320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSC05_RS00325	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSC05_RS00335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSC05_RS00340	COG2814	Major facilitator Superfamily
FSC05_RS00345	COG1335	isochorismatase
FSC05_RS00350	COG0385	Bile acid
FSC05_RS00365	COG3830	Belongs to the UPF0237 family
FSC05_RS00365	COG0560	Phosphoserine phosphatase
FSC05_RS00385	COG0753	catalase activity
FSC05_RS00445	COG1464	Belongs to the NlpA lipoprotein family
FSC05_RS00450	COG1464	Belongs to the NlpA lipoprotein family
FSC05_RS00455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC05_RS00460	COG2011	ABC-type metal ion transport system permease component
FSC05_RS00465	COG0534	Mate efflux family protein
FSC05_RS00470	COG0436	Aminotransferase
FSC05_RS00475	COG2733	membrane
FSC05_RS00490	COG2918	glutathione biosynthetic process
FSC05_RS00495	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FSC05_RS00505	COG3150	esterase
FSC05_RS00545	COG0471	metal ion transport
FSC05_RS00560	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FSC05_RS00565	COG4266	Belongs to the allantoicase family
FSC05_RS00570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC05_RS00575	COG1247	-acetyltransferase
FSC05_RS00615	COG0625	glutathione transferase activity
FSC05_RS00625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FSC05_RS00640	COG1393	Belongs to the ArsC family
FSC05_RS00645	COG0708	Exodeoxyribonuclease III
FSC05_RS00665	COG2801	Transposase and inactivated derivatives
FSC05_RS00700	COG3188	usher protein
FSC05_RS00720	COG0189	ligase activity
FSC05_RS00725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSC05_RS00730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC05_RS00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FSC05_RS00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSC05_RS00780	COG2119	membrane
FSC05_RS00785	COG0426	domain, Protein
FSC05_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC05_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSC05_RS00835	COG1902	pentaerythritol trinitrate reductase activity
FSC05_RS00840	COG1519	Transferase
FSC05_RS00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC05_RS00850	COG0668	transmembrane transport
FSC05_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC05_RS00865	COG0431	NADPH-dependent FMN reductase
FSC05_RS00880	COG2205	protein histidine kinase activity
FSC05_RS00880	COG0784	Response regulator, receiver
FSC05_RS00885	COG3162	membrane
FSC05_RS00890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC05_RS00910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC05_RS00920	COG3706	GGDEF domain
FSC05_RS00925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSC05_RS00930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC05_RS00940	COG2814	Major facilitator Superfamily
FSC05_RS00945	COG0629	single-stranded DNA binding
FSC05_RS00960	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FSC05_RS01015	COG1785	Belongs to the alkaline phosphatase family
FSC05_RS01020	COG1785	Belongs to the alkaline phosphatase family
FSC05_RS01095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FSC05_RS01100	COG0732	type I restriction modification DNA specificity domain
FSC05_RS01105	COG4804	nuclease activity
FSC05_RS01125	COG0582	viral genome integration into host DNA
FSC05_RS01135	COG3158	transport of potassium into the cell
FSC05_RS01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FSC05_RS01190	COG0697	spore germination
FSC05_RS01210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSC05_RS01240	COG0427	acetyl-CoA hydrolase
FSC05_RS01245	COG2205	protein histidine kinase activity
FSC05_RS01250	COG0745	RESPONSE REGULATOR receiver
FSC05_RS01265	COG4221	oxidoreductase activity
FSC05_RS01275	COG0488	(ABC) transporter
FSC05_RS01305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC05_RS01315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC05_RS01320	COG0275	rRNA processing
FSC05_RS01335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSC05_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSC05_RS01350	COG2226	methyltransferase
FSC05_RS01355	COG3385	transposase activity
FSC05_RS01370	COG0675	Transposase, IS605 OrfB family
FSC05_RS01415	COG0069	glutamate synthase activity
FSC05_RS01415	COG0067	glutamate synthase
FSC05_RS01415	COG0070	glutamate synthase
FSC05_RS01420	COG0493	'glutamate synthase
FSC05_RS01430	COG1704	LemA family
FSC05_RS01435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FSC05_RS01455	COG3307	-O-antigen
FSC05_RS01475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC05_RS01480	COG1758	RNA polymerase activity
FSC05_RS01485	COG0194	GDP metabolic process
FSC05_RS01505	COG0228	four-way junction DNA binding
FSC05_RS01510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSC05_RS01520	COG0335	large ribosomal subunit rRNA binding
FSC05_RS01530	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC05_RS01535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC05_RS01540	COG5380	lipid catabolic process
FSC05_RS01550	COG3547	Transposase (IS116 IS110 IS902 family)
FSC05_RS01560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSC05_RS01585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSC05_RS01595	COG0277	FAD linked oxidase domain protein
FSC05_RS01610	COG2814	Major facilitator Superfamily
FSC05_RS01620	COG0628	permease
FSC05_RS01625	COG1192	Involved in chromosome partitioning
FSC05_RS01650	COG2226	methyltransferase
FSC05_RS01670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSC05_RS01675	COG0254	rRNA binding
FSC05_RS01680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC05_RS01685	COG0534	Mate efflux family protein
FSC05_RS01695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC05_RS01700	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS01720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC05_RS01745	COG1127	ABC transporter
FSC05_RS01750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSC05_RS01755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSC05_RS01760	COG2854	intermembrane phospholipid transfer
FSC05_RS01770	COG0598	Magnesium transport protein CorA
FSC05_RS01785	COG1040	competence protein
FSC05_RS01790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSC05_RS01800	COG2937	Belongs to the GPAT DAPAT family
FSC05_RS01805	COG1946	Acyl-CoA thioesterase
FSC05_RS01810	COG1301	dicarboxylic acid transport
FSC05_RS01830	COG1959	2 iron, 2 sulfur cluster binding
FSC05_RS01840	COG0433	COG0433 Predicted ATPase
FSC05_RS01885	COG0088	Forms part of the polypeptide exit tunnel
FSC05_RS01915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSC05_RS01950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSC05_RS01955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSC05_RS01965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSC05_RS02000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSC05_RS02005	COG0202	RNA polymerase activity
FSC05_RS02015	COG2072	flavoprotein involved in K transport
FSC05_RS02020	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS02025	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FSC05_RS02065	COG0697	spore germination
FSC05_RS02075	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FSC05_RS02080	COG0339	signal peptide processing
FSC05_RS02090	COG0557	exoribonuclease II activity
FSC05_RS02140	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSC05_RS02170	COG3040	lipid binding
FSC05_RS02230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_RS02230	COG2813	Specifically methylates the guanine in position
FSC05_RS02235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_RS02240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSC05_RS02250	COG3128	pkhd-type hydroxylase
FSC05_RS02255	COG4774	siderophore transport
FSC05_RS02260	COG4771	TonB-dependent receptor
FSC05_RS02270	COG0740	serine-type endopeptidase activity
FSC05_RS02285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC05_RS02285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC05_RS02295	COG0857	belongs to the CobB CobQ family
FSC05_RS02295	COG0280	phosphate acetyltransferase
FSC05_RS02300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSC05_RS02330	COG0793	Belongs to the peptidase S41A family
FSC05_RS02345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSC05_RS02360	COG0084	hydrolase, TatD family'
FSC05_RS02365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FSC05_RS02370	COG3385	transposase activity
FSC05_RS02375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSC05_RS02395	COG1058	Belongs to the CinA family
FSC05_RS02395	COG1546	Belongs to the CinA family
FSC05_RS02415	COG2814	Major facilitator Superfamily
FSC05_RS02420	COG0697	spore germination
FSC05_RS02445	COG3622	Belongs to the hyi family
FSC05_RS02455	COG1024	Enoyl-CoA hydratase
FSC05_RS02460	COG0784	Response regulator, receiver
FSC05_RS02460	COG5002	protein histidine kinase activity
FSC05_RS02460	COG2205	protein histidine kinase activity
FSC05_RS02465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC05_RS02480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC05_RS02500	COG1862	Preprotein translocase
FSC05_RS02510	COG5001	Diguanylate cyclase
FSC05_RS02510	COG4251	negative regulation of phosphorylation
FSC05_RS02510	COG3706	GGDEF domain
FSC05_RS02510	COG2203	Gaf domain
FSC05_RS02515	COG1704	LemA family
FSC05_RS02525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSC05_RS02540	COG5002	protein histidine kinase activity
FSC05_RS02545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSC05_RS02565	COG0438	transferase activity, transferring glycosyl groups
FSC05_RS02610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSC05_RS02640	COG3547	Transposase (IS116 IS110 IS902 family)
FSC05_RS02690	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS02695	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS02705	COG2205	protein histidine kinase activity
FSC05_RS02710	COG0745	RESPONSE REGULATOR receiver
FSC05_RS02720	COG1113	amino acid transport
FSC05_RS02730	COG2315	Protein conserved in bacteria
FSC05_RS02735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FSC05_RS02755	COG2096	Adenosyltransferase
FSC05_RS02760	COG4206	TonB-dependent receptor
FSC05_RS02805	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSC05_RS02810	COG0285	dihydrofolate synthase activity
FSC05_RS02830	COG0675	Transposase, IS605 OrfB family
FSC05_RS02835	COG0450	alkyl hydroperoxide reductase
FSC05_RS02850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSC05_RS02855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSC05_RS02880	COG2885	chlorophyll binding
FSC05_RS02885	COG2199	diguanylate cyclase activity
FSC05_RS02950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSC05_RS02955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSC05_RS02975	COG0494	nUDIX hydrolase
FSC05_RS02985	COG1214	PFAM Peptidase M22, glycoprotease
FSC05_RS02990	COG1968	undecaprenyl-diphosphatase activity
FSC05_RS03010	COG4269	membrane
FSC05_RS03025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSC05_RS03035	COG2132	Multicopper oxidase
FSC05_RS03050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSC05_RS03065	COG0352	thiamine-phosphate diphosphorylase activity
FSC05_RS03065	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC05_RS03065	COG0351	phosphomethylpyrimidine kinase
FSC05_RS03090	COG0251	oxidation-reduction process
FSC05_RS03095	COG1113	amino acid transport
FSC05_RS03115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSC05_RS03140	COG0456	acetyltransferase
FSC05_RS03150	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSC05_RS03155	COG0492	ferredoxin-NADP+ reductase activity
FSC05_RS03160	COG1674	ftsk spoiiie
FSC05_RS03160	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSC05_RS03175	COG2894	cell division
FSC05_RS03190	COG0204	Acyl-transferase
FSC05_RS03195	COG2885	chlorophyll binding
FSC05_RS03200	COG0210	DNA helicase
FSC05_RS03210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC05_RS03225	COG0121	glutamine amidotransferase
FSC05_RS03240	COG2914	Belongs to the UPF0125 (RnfH) family
FSC05_RS03245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC05_RS03250	COG0735	belongs to the Fur family
FSC05_RS03280	COG0420	3'-5' exonuclease activity
FSC05_RS03300	COG2050	protein possibly involved in aromatic compounds catabolism
FSC05_RS03305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSC05_RS03315	COG0582	viral genome integration into host DNA
FSC05_RS03340	COG1802	Transcriptional regulator
FSC05_RS03390	COG3177	Filamentation induced by cAMP protein fic
FSC05_RS03415	COG1649	PFAM Uncharacterised BCR, COG1649
FSC05_RS03415	COG0726	polysaccharide deacetylase
FSC05_RS03420	COG1215	transferase activity, transferring glycosyl groups
FSC05_RS03435	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FSC05_RS03480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC05_RS03485	COG0154	amidase activity
FSC05_RS03490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC05_RS03495	COG1077	Cell shape determining protein MreB Mrl
FSC05_RS03500	COG1792	Involved in formation and maintenance of cell shape
FSC05_RS03505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FSC05_RS03510	COG0424	maF-like protein
FSC05_RS03515	COG1530	ribonuclease E activity
FSC05_RS03520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC05_RS03560	COG0625	glutathione transferase activity
FSC05_RS03570	COG0675	Transposase, IS605 OrfB family
FSC05_RS03585	COG1113	amino acid transport
FSC05_RS03590	COG2828	Protein conserved in bacteria
FSC05_RS03595	COG0142	geranyltranstransferase activity
FSC05_RS03605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC05_RS03625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSC05_RS03635	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FSC05_RS03640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC05_RS03645	COG0839	Belongs to the complex I subunit 6 family
FSC05_RS03650	COG0713	ATP synthesis coupled electron transport
FSC05_RS03655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC05_RS03660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC05_RS03675	COG1278	Cold shock
FSC05_RS03685	COG0583	DNA-binding transcription factor activity
FSC05_RS03710	COG0668	transmembrane transport
FSC05_RS03720	COG2081	HI0933 family
FSC05_RS03740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FSC05_RS03760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC05_RS03760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC05_RS03765	COG0489	protein tyrosine kinase activity
FSC05_RS03780	COG2358	TRAP transporter, solute receptor (TAXI family
FSC05_RS03850	COG0442	prolyl-tRNA aminoacylation
FSC05_RS03890	COG0840	transmembrane signaling receptor activity
FSC05_RS03895	COG0643	Histidine kinase
FSC05_RS03895	COG2198	Histidine kinase
FSC05_RS03895	COG0784	Response regulator, receiver
FSC05_RS03910	COG5510	response to toxic substance
FSC05_RS03920	COG2832	Protein of unknown function (DUF454)
FSC05_RS03925	COG1376	ErfK ybiS ycfS ynhG family protein
FSC05_RS03980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSC05_RS03990	COG1289	transmembrane transporter activity
FSC05_RS03995	COG2814	Major facilitator Superfamily
FSC05_RS04010	COG0786	glutamate:sodium symporter activity
FSC05_RS04015	COG1115	amino acid carrier protein
FSC05_RS04020	COG2059	Chromate
FSC05_RS04025	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC05_RS04035	COG1607	acyl-coa hydrolase
FSC05_RS04045	COG2814	Major facilitator Superfamily
FSC05_RS04050	COG0583	DNA-binding transcription factor activity
FSC05_RS04070	COG0523	cobalamin synthesis protein
FSC05_RS04075	COG4681	YaeQ
FSC05_RS04085	COG2199	diguanylate cyclase activity
FSC05_RS04085	COG2203	Gaf domain
FSC05_RS04115	COG0477	Major facilitator Superfamily
FSC05_RS04125	COG2066	Belongs to the glutaminase family
FSC05_RS04135	COG0306	phosphate transporter
FSC05_RS04175	COG4771	TonB-dependent receptor
FSC05_RS04200	COG4181	ATPase activity
FSC05_RS04205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FSC05_RS04215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC05_RS04225	COG0583	DNA-binding transcription factor activity
FSC05_RS04235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_RS04240	COG1773	rubredoxin
FSC05_RS04245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSC05_RS04275	COG3118	belongs to the thioredoxin family
FSC05_RS04295	COG1253	flavin adenine dinucleotide binding
FSC05_RS04315	COG3015	lipoprotein NlpE involved in copper resistance
FSC05_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_RS04350	COG0804	urea catabolic process
FSC05_RS04365	COG2801	Transposase and inactivated derivatives
FSC05_RS04380	COG0830	nickel cation binding
FSC05_RS04395	COG0742	ribosomal rna small subunit methyltransferase
FSC05_RS04400	COG0768	penicillin binding
FSC05_RS04425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSC05_RS04430	COG2878	Part of a membrane complex involved in electron transport
FSC05_RS04435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSC05_RS04445	COG3384	dioxygenase
FSC05_RS04455	COG2234	aminopeptidase activity
FSC05_RS04470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSC05_RS04485	COG3328	transposase activity
FSC05_RS04495	COG0675	Transposase, IS605 OrfB family
FSC05_RS04510	COG2186	Transcriptional regulator
FSC05_RS04520	COG0277	FAD linked oxidase domain protein
FSC05_RS04550	COG3079	Belongs to the UPF0149 family
FSC05_RS04555	COG0006	proline dipeptidase activity
FSC05_RS04565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC05_RS04570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC05_RS04605	COG2816	NAD+ diphosphatase activity
FSC05_RS04620	COG1388	LysM domain
FSC05_RS04620	COG0741	lytic transglycosylase activity
FSC05_RS04625	COG4166	transmembrane transport
FSC05_RS04630	COG4174	ABC transporter (Permease)
FSC05_RS04635	COG4239	(ABC) transporter, permease
FSC05_RS04640	COG4172	Belongs to the ABC transporter superfamily
FSC05_RS04670	COG0833	amino acid
FSC05_RS04690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSC05_RS04695	COG0418	dihydroorotase activity
FSC05_RS04700	COG3706	GGDEF domain
FSC05_RS04700	COG4251	negative regulation of phosphorylation
FSC05_RS04700	COG2203	Gaf domain
FSC05_RS04700	COG5001	Diguanylate cyclase
FSC05_RS04720	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC05_RS04720	COG1902	pentaerythritol trinitrate reductase activity
FSC05_RS04820	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FSC05_RS04840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC05_RS04845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSC05_RS04850	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSC05_RS04855	COG3385	transposase activity
FSC05_RS04880	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS04885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC05_RS04895	COG2175	clavaminate synthase activity
FSC05_RS04915	COG0052	Belongs to the universal ribosomal protein uS2 family
FSC05_RS04940	COG2951	lytic endotransglycosylase activity
FSC05_RS04955	COG0842	Transport permease protein
FSC05_RS04960	COG1131	(ABC) transporter
FSC05_RS05015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC05_RS05035	COG3634	alkyl hydroperoxide reductase activity
FSC05_RS05040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC05_RS05055	COG0640	Transcriptional regulator
FSC05_RS05065	COG0798	PFAM Bile acid sodium symporter
FSC05_RS05070	COG0431	NADPH-dependent FMN reductase
FSC05_RS05075	COG0789	Transcriptional regulator
FSC05_RS05090	COG1720	tRNA m6t6A37 methyltransferase activity
FSC05_RS05100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSC05_RS05110	COG0745	RESPONSE REGULATOR receiver
FSC05_RS05115	COG0642	Histidine kinase
FSC05_RS05135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC05_RS05140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSC05_RS05145	COG3139	Protein of unknown function (DUF1315)
FSC05_RS05155	COG1301	dicarboxylic acid transport
FSC05_RS05160	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS05165	COG0693	protein deglycase activity
FSC05_RS05175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSC05_RS05180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSC05_RS05205	COG1047	Peptidyl-prolyl cis-trans
FSC05_RS05210	COG1252	NADH dehydrogenase
FSC05_RS05215	COG1686	Belongs to the peptidase S11 family
FSC05_RS05230	COG1187	pseudouridine synthase activity
FSC05_RS05240	COG0739	heme binding
FSC05_RS05250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC05_RS05260	COG0612	Peptidase, M16
FSC05_RS05295	COG0352	thiamine-phosphate diphosphorylase activity
FSC05_RS05335	COG0596	Alpha beta hydrolase
FSC05_RS05340	COG1309	transcriptional regulator
FSC05_RS05380	COG1278	Cold shock
FSC05_RS05395	COG2070	2-Nitropropane dioxygenase
FSC05_RS05420	COG2391	methyltransferase activity
FSC05_RS05430	COG3634	alkyl hydroperoxide reductase activity
FSC05_RS05460	COG1643	Atp-dependent helicase
FSC05_RS05485	COG0517	IMP dehydrogenase activity
FSC05_RS05485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSC05_RS05490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FSC05_RS05500	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FSC05_RS05505	COG1137	ATPase activity
FSC05_RS05540	COG4122	O-methyltransferase activity
FSC05_RS05550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSC05_RS05600	COG2011	ABC-type metal ion transport system permease component
FSC05_RS05605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC05_RS05625	COG0138	bifunctional purine biosynthesis protein purh
FSC05_RS05630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FSC05_RS05670	COG2308	Evidence 4 Homologs of previously reported genes of
FSC05_RS05680	COG1305	Transglutaminase-like
FSC05_RS05695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSC05_RS05710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSC05_RS05715	COG0360	Binds together with S18 to 16S ribosomal RNA
FSC05_RS05725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FSC05_RS05730	COG1845	cytochrome c oxidase, subunit III
FSC05_RS05735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSC05_RS05740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSC05_RS05765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC05_RS05780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSC05_RS05790	COG3781	membrane
FSC05_RS05810	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS05815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC05_RS05830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSC05_RS05840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FSC05_RS05855	COG0477	Major facilitator Superfamily
FSC05_RS05900	COG0786	glutamate:sodium symporter activity
FSC05_RS05935	COG0308	aminopeptidase N
FSC05_RS05945	COG0589	response to stress
FSC05_RS05950	COG0589	response to stress
FSC05_RS05960	COG3135	benzoate transporter
FSC05_RS05970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSC05_RS05985	COG0183	Belongs to the thiolase family
FSC05_RS05995	COG2030	dehydratase
FSC05_RS06010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSC05_RS06015	COG0824	Thioesterase
FSC05_RS06020	COG1454	alcohol dehydrogenase
FSC05_RS06025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSC05_RS06045	COG0069	glutamate synthase activity
FSC05_RS06050	COG2197	response regulator
FSC05_RS06055	COG4585	Histidine kinase
FSC05_RS06060	COG2850	peptidyl-arginine hydroxylation
FSC05_RS06065	COG0424	maF-like protein
FSC05_RS06090	COG0697	spore germination
FSC05_RS06130	COG3698	Phosphodiester glycosidase
FSC05_RS06150	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC05_RS06150	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC05_RS06150	COG0506	proline dehydrogenase activity
FSC05_RS06160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC05_RS06165	COG1027	Aspartate ammonia-lyase
FSC05_RS06170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSC05_RS06175	COG0583	DNA-binding transcription factor activity
FSC05_RS06180	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS06185	COG2814	Major facilitator Superfamily
FSC05_RS06190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSC05_RS06205	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC05_RS06205	COG1902	pentaerythritol trinitrate reductase activity
FSC05_RS06235	COG0148	phosphopyruvate hydratase activity
FSC05_RS06250	COG0772	Belongs to the SEDS family
FSC05_RS06265	COG2137	regulation of response to DNA damage stimulus
FSC05_RS06275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSC05_RS06280	COG1011	Hydrolase
FSC05_RS06300	COG0268	Binds directly to 16S ribosomal RNA
FSC05_RS06305	COG0702	epimerase
FSC05_RS06310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC05_RS06325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSC05_RS06355	COG0316	Belongs to the HesB IscA family
FSC05_RS06360	COG0822	iron-sulfur transferase activity
FSC05_RS06390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC05_RS06445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSC05_RS06465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC05_RS06475	COG0133	tryptophan synthase activity
FSC05_RS06480	COG0617	tRNA 3'-terminal CCA addition
FSC05_RS06480	COG0517	IMP dehydrogenase activity
FSC05_RS06480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSC05_RS06510	COG0612	Peptidase, M16
FSC05_RS06515	COG0552	protein localization to endoplasmic reticulum
FSC05_RS06560	COG0693	protein deglycase activity
FSC05_RS06570	COG1283	sodium-dependent phosphate transmembrane transporter activity
FSC05_RS06580	COG1346	cytolysis
FSC05_RS06590	COG0583	DNA-binding transcription factor activity
FSC05_RS06610	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FSC05_RS06615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC05_RS06640	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS06645	COG2207	Transcriptional regulator
FSC05_RS06650	COG2814	Major facilitator Superfamily
FSC05_RS06660	COG1271	oxidase subunit
FSC05_RS06665	COG1294	oxidase, subunit
FSC05_RS06675	COG1525	nuclease
FSC05_RS06725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC05_RS06730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSC05_RS06745	COG1113	amino acid transport
FSC05_RS06755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC05_RS06765	COG2814	Major facilitator Superfamily
FSC05_RS06785	COG1132	(ABC) transporter
FSC05_RS06805	COG0668	transmembrane transport
FSC05_RS06810	COG3122	Protein conserved in bacteria
FSC05_RS06830	COG0640	Transcriptional regulator
FSC05_RS06835	COG2937	Belongs to the GPAT DAPAT family
FSC05_RS06840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC05_RS06845	COG1116	anion transmembrane transporter activity
FSC05_RS06845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC05_RS06855	COG2223	nitrite transmembrane transporter activity
FSC05_RS06860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_RS06860	COG2146	nitrite reductase [NAD(P)H] activity
FSC05_RS06865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_RS06870	COG0243	molybdopterin cofactor binding
FSC05_RS06880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSC05_RS06895	COG0315	cyclic pyranopterin monophosphate synthase activity
FSC05_RS06895	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSC05_RS06900	COG0303	'Molybdopterin
FSC05_RS06905	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSC05_RS06910	COG4149	molybdate abc transporter
FSC05_RS06915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FSC05_RS06940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_RS06945	COG0183	Belongs to the thiolase family
FSC05_RS06950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC05_RS06955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC05_RS06960	COG3135	benzoate transporter
FSC05_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_RS07010	COG2223	nitrite transmembrane transporter activity
FSC05_RS07020	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FSC05_RS07025	COG2116	formate transmembrane transporter activity
FSC05_RS07030	COG0515	serine threonine protein kinase
FSC05_RS07045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_RS07080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC05_RS07085	COG1309	transcriptional regulator
FSC05_RS07090	COG1012	belongs to the aldehyde dehydrogenase family
FSC05_RS07110	COG0745	RESPONSE REGULATOR receiver
FSC05_RS07120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSC05_RS07145	COG2885	chlorophyll binding
FSC05_RS07155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSC05_RS07160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC05_RS07165	COG0730	response to heat
FSC05_RS07190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC05_RS07195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSC05_RS07200	COG0022	dehydrogenase e1 component
FSC05_RS07205	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSC05_RS07210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC05_RS07220	COG1063	alcohol dehydrogenase
FSC05_RS07225	COG4628	conserved protein (DUF2132)
FSC05_RS07235	COG2801	Transposase and inactivated derivatives
FSC05_RS07345	COG0596	Alpha beta hydrolase
FSC05_RS07380	COG0511	ligase activity, forming carbon-carbon bonds
FSC05_RS07385	COG0439	Biotin carboxylase
FSC05_RS07400	COG2814	Major facilitator Superfamily
FSC05_RS07435	COG1546	Belongs to the CinA family
FSC05_RS07435	COG1058	Belongs to the CinA family
FSC05_RS07445	COG0372	Belongs to the citrate synthase family
FSC05_RS07465	COG0477	Major facilitator Superfamily
FSC05_RS07480	COG0542	response to heat
FSC05_RS07485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSC05_RS07505	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSC05_RS07515	COG0569	domain protein
FSC05_RS07520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSC05_RS07540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSC05_RS07550	COG1585	Membrane protein implicated in regulation of membrane protease activity
FSC05_RS07565	COG1294	oxidase, subunit
FSC05_RS07570	COG4890	Cyd operon protein YbgT
FSC05_RS07610	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS07615	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS07625	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC05_RS07630	COG2207	Transcriptional regulator
FSC05_RS07635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC05_RS07640	COG0730	response to heat
FSC05_RS07645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC05_RS07675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC05_RS07695	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC05_RS07710	COG0575	Belongs to the CDS family
FSC05_RS07715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSC05_RS07720	COG0233	cytoplasmic translational termination
FSC05_RS07735	COG3852	Histidine kinase
FSC05_RS07740	COG2204	response regulator
FSC05_RS07750	COG0583	DNA-binding transcription factor activity
FSC05_RS07780	COG1253	flavin adenine dinucleotide binding
FSC05_RS07800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FSC05_RS07805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSC05_RS07820	COG2431	L-lysine efflux transmembrane transporter activity
FSC05_RS07825	COG0284	orotidine-5'-phosphate decarboxylase activity
FSC05_RS07835	COG0776	regulation of translation
FSC05_RS07865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSC05_RS07900	COG0084	hydrolase, TatD family'
FSC05_RS07920	COG1663	tetraacyldisaccharide 4'-kinase activity
FSC05_RS07925	COG1132	(ABC) transporter
FSC05_RS07935	COG0811	peptide transport
FSC05_RS07940	COG1475	DNA binding
FSC05_RS07945	COG1192	Involved in chromosome partitioning
FSC05_RS07955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSC05_RS07960	COG3178	'Phosphotransferase
FSC05_RS07970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC05_RS07975	COG1923	regulation of RNA biosynthetic process
FSC05_RS07985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSC05_RS07990	COG0802	atpase or kinase
FSC05_RS08015	COG2707	UPF0756 membrane protein
FSC05_RS08025	COG0583	DNA-binding transcription factor activity
FSC05_RS08030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC05_RS08060	COG0519	Catalyzes the synthesis of GMP from XMP
FSC05_RS08060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC05_RS08065	COG2353	YceI-like domain
FSC05_RS08075	COG3385	transposase activity
FSC05_RS08080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSC05_RS08085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSC05_RS08120	COG1254	Belongs to the acylphosphatase family
FSC05_RS08125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSC05_RS08125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSC05_RS08130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FSC05_RS08150	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_RS08160	COG3327	negative regulation of DNA-templated transcription, initiation
FSC05_RS08165	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FSC05_RS08170	COG0183	Belongs to the thiolase family
FSC05_RS08175	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC05_RS08180	COG1024	Enoyl-CoA hydratase
FSC05_RS08185	COG1024	Enoyl-CoA hydratase
FSC05_RS08190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC05_RS08195	COG2151	metal-sulfur cluster biosynthetic enzyme
FSC05_RS08200	COG3396	Phenylacetate-CoA oxygenase
FSC05_RS08205	COG3460	Phenylacetate-CoA oxygenase
FSC05_RS08210	COG3396	Phenylacetate-CoA oxygenase
FSC05_RS08215	COG2030	dehydratase
FSC05_RS08215	COG1012	belongs to the aldehyde dehydrogenase family
FSC05_RS08220	COG2814	Major facilitator Superfamily
FSC05_RS08225	COG0783	Belongs to the Dps family
FSC05_RS08255	COG2801	Transposase and inactivated derivatives
FSC05_RS08265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSC05_RS08270	COG0183	Belongs to the thiolase family
FSC05_RS08280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC05_RS08285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC05_RS08290	COG1414	Transcriptional regulator
FSC05_RS08300	COG4774	siderophore transport
FSC05_RS08315	COG0579	oxidoreductase
FSC05_RS08360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSC05_RS08395	COG0642	Histidine kinase
FSC05_RS08410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FSC05_RS08435	COG2816	NAD+ diphosphatase activity
FSC05_RS08440	COG3046	protein related to deoxyribodipyrimidine photolyase
FSC05_RS08455	COG2351	hydroxyisourate hydrolase activity
FSC05_RS08475	COG1136	(ABC) transporter
FSC05_RS08485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_RS08510	COG0204	Acyl-transferase
FSC05_RS08535	COG0012	GTP binding
FSC05_RS08545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FSC05_RS08560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSC05_RS08570	COG0386	Belongs to the glutathione peroxidase family
FSC05_RS08575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSC05_RS08580	COG0436	Aminotransferase
FSC05_RS08585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC05_RS08585	COG2755	lipolytic protein G-D-S-L family
FSC05_RS08625	COG2815	serine threonine protein kinase
FSC05_RS08625	COG0515	serine threonine protein kinase
FSC05_RS08655	COG1610	YqeY-like protein
FSC05_RS08670	COG4783	chaperone-mediated protein folding
FSC05_RS08735	COG0513	Belongs to the DEAD box helicase family
FSC05_RS08755	COG2363	Small membrane protein
FSC05_RS08775	COG0659	secondary active sulfate transmembrane transporter activity
FSC05_RS08785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSC05_RS08805	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_RS08810	COG1309	transcriptional regulator
FSC05_RS08815	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS08820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSC05_RS08825	COG1024	Enoyl-CoA hydratase
FSC05_RS08830	COG4770	biotin carboxylase activity
FSC05_RS08845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC05_RS08860	COG0540	Belongs to the ATCase OTCase family
FSC05_RS08880	COG1765	OsmC-like protein
FSC05_RS08890	COG0667	Aldo Keto reductase
FSC05_RS08905	COG0501	Belongs to the peptidase M48B family
FSC05_RS08910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSC05_RS08925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSC05_RS08935	COG0527	aspartate kinase activity
FSC05_RS08945	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSC05_RS08955	COG1215	transferase activity, transferring glycosyl groups
FSC05_RS08965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSC05_RS08970	COG2252	PERMEase
FSC05_RS09000	COG0714	Associated with various cellular activities
FSC05_RS09005	COG2879	small protein
FSC05_RS09010	COG1966	Carbon starvation protein
FSC05_RS09015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSC05_RS09020	COG1509	lysine 2,3-aminomutase activity
FSC05_RS09055	COG1067	ATP-dependent peptidase activity
FSC05_RS09060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FSC05_RS09065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSC05_RS09070	COG0583	DNA-binding transcription factor activity
FSC05_RS09080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FSC05_RS09095	COG1686	Belongs to the peptidase S11 family
FSC05_RS09100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSC05_RS09135	COG0616	signal peptide processing
FSC05_RS09140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSC05_RS09150	COG0573	inorganic phosphate transmembrane transporter activity
FSC05_RS09160	COG0076	glutamate decarboxylase activity
FSC05_RS09165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSC05_RS09220	COG1570	exodeoxyribonuclease VII activity
FSC05_RS09230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC05_RS09235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC05_RS09240	COG2194	sulfuric ester hydrolase activity
FSC05_RS09245	COG0745	RESPONSE REGULATOR receiver
FSC05_RS09250	COG0642	Histidine kinase
FSC05_RS09285	COG3646	Phage regulatory protein
FSC05_RS09300	COG0582	viral genome integration into host DNA
FSC05_RS09305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSC05_RS09315	COG2814	Major facilitator Superfamily
FSC05_RS09320	COG1733	regulation of RNA biosynthetic process
FSC05_RS09325	COG0702	epimerase
FSC05_RS09355	COG0556	nucleotide-excision repair
FSC05_RS09375	COG0436	Aminotransferase
FSC05_RS09405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSC05_RS09410	COG1381	Involved in DNA repair and RecF pathway recombination
FSC05_RS09420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSC05_RS09425	COG0571	ribonuclease III activity
FSC05_RS09435	COG0681	Belongs to the peptidase S26 family
FSC05_RS09450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC05_RS09460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC05_RS09475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSC05_RS09500	COG4208	sulfate ABC transporter
FSC05_RS09505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSC05_RS09510	COG0583	DNA-binding transcription factor activity
FSC05_RS09530	COG0602	queuosine metabolic process
FSC05_RS09535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSC05_RS09545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSC05_RS09550	COG2353	YceI-like domain
FSC05_RS09555	COG1051	belongs to the nudix hydrolase family
FSC05_RS09555	COG1056	cytidyltransferase-related domain
FSC05_RS09560	COG1024	Enoyl-CoA hydratase
FSC05_RS09565	COG0778	Nitroreductase
FSC05_RS09580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSC05_RS09580	COG0047	phosphoribosylformylglycinamidine synthase activity
FSC05_RS09600	COG2255	four-way junction helicase activity
FSC05_RS09610	COG0824	Thioesterase
FSC05_RS09630	COG0823	Involved in the tonB-independent uptake of proteins
FSC05_RS09650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC05_RS09680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC05_RS09685	COG0628	permease
FSC05_RS09690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSC05_RS09695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSC05_RS09715	COG2333	competence protein COMEC
FSC05_RS09715	COG0658	competence protein
FSC05_RS09720	COG1136	(ABC) transporter
FSC05_RS09725	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC05_RS09740	COG1671	Belongs to the UPF0178 family
FSC05_RS09780	COG1280	lysine exporter protein (LysE YggA)
FSC05_RS09785	COG1522	sequence-specific DNA binding
FSC05_RS09795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSC05_RS09810	COG0019	diaminopimelate decarboxylase activity
FSC05_RS09820	COG1113	amino acid transport
FSC05_RS09825	COG1115	amino acid carrier protein
FSC05_RS09845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FSC05_RS09850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSC05_RS09885	COG0583	DNA-binding transcription factor activity
FSC05_RS09895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FSC05_RS09905	COG0174	glutamine synthetase
FSC05_RS09910	COG0512	Glutamine amidotransferase of anthranilate synthase
FSC05_RS09940	COG3706	GGDEF domain
FSC05_RS09955	COG3739	integral membrane protein
FSC05_RS09960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FSC05_RS09970	COG1741	Belongs to the pirin family
FSC05_RS09975	COG3842	ATPase activity
FSC05_RS09980	COG1840	ABC-type Fe3 transport system, periplasmic component
FSC05_RS10010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC05_RS10015	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FSC05_RS10025	COG0037	tRNA processing
FSC05_RS10030	COG0739	heme binding
FSC05_RS10030	COG0741	lytic transglycosylase activity
FSC05_RS10030	COG1196	nuclear chromosome segregation
FSC05_RS10035	COG0501	Belongs to the peptidase M48B family
FSC05_RS10045	COG2239	Acts as a magnesium transporter
FSC05_RS10080	COG1597	lipid kinase activity
FSC05_RS10100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSC05_RS10145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC05_RS10155	COG1534	Rna-binding protein
FSC05_RS10170	COG0505	Belongs to the CarA family
FSC05_RS10185	COG0415	Belongs to the DNA photolyase family
FSC05_RS10190	COG0110	maltose O-acetyltransferase activity
FSC05_RS10195	COG0589	response to stress
FSC05_RS10205	COG2321	neutral zinc metallopeptidase
FSC05_RS10210	COG2354	Protein conserved in bacteria
FSC05_RS10225	COG2268	Band 7 protein
FSC05_RS10235	COG1215	transferase activity, transferring glycosyl groups
FSC05_RS10250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSC05_RS10260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC05_RS10275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSC05_RS10280	COG1053	succinate dehydrogenase
FSC05_RS10285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FSC05_RS10300	COG2072	flavoprotein involved in K transport
FSC05_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_RS10315	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FSC05_RS10330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC05_RS10330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSC05_RS10360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC05_RS10370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSC05_RS10385	COG0564	pseudouridine synthase activity
FSC05_RS10395	COG0358	DNA primase activity
FSC05_RS10410	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FSC05_RS10440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSC05_RS10480	COG0586	Pfam SNARE associated Golgi protein
FSC05_RS10505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSC05_RS10515	COG0321	lipoyl(octanoyl) transferase activity
FSC05_RS10530	COG0531	amino acid
FSC05_RS10535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FSC05_RS10540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSC05_RS10540	COG1648	precorrin-2 dehydrogenase activity
FSC05_RS10545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSC05_RS10555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FSC05_RS10580	COG0671	phosphoesterase, PA-phosphatase related
FSC05_RS10585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_RS10595	COG1538	Outer membrane efflux protein
FSC05_RS10600	COG0393	Putative heavy-metal-binding
FSC05_RS10605	COG0393	Putative heavy-metal-binding
FSC05_RS10620	COG0525	valine-tRNA ligase activity
FSC05_RS10635	COG2852	Protein conserved in bacteria
FSC05_RS10650	COG2323	membrane
FSC05_RS10660	COG0765	amino acid transport
FSC05_RS10665	COG0765	amino acid transport
FSC05_RS10670	COG1126	abc transporter atp-binding protein
FSC05_RS10675	COG3338	carbonate dehydratase activity
FSC05_RS10690	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC05_RS10705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC05_RS10710	COG2205	protein histidine kinase activity
FSC05_RS10715	COG0745	RESPONSE REGULATOR receiver
FSC05_RS10730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC05_RS10735	COG1652	LysM domain
FSC05_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_RS10760	COG1399	metal-binding, possibly nucleic acid-binding protein
FSC05_RS10765	COG3101	peptidyl-lysine hydroxylation
FSC05_RS10770	COG0009	L-threonylcarbamoyladenylate synthase
FSC05_RS10780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSC05_RS10785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSC05_RS10800	COG4106	trans-aconitate 2-methyltransferase activity
FSC05_RS10815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_RS10815	COG0596	Alpha beta hydrolase
FSC05_RS10815	COG2226	methyltransferase
FSC05_RS10820	COG2193	ferroxidase activity
FSC05_RS10825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSC05_RS10830	COG3115	cell septum assembly
FSC05_RS10835	COG1196	nuclear chromosome segregation
FSC05_RS10845	COG0730	response to heat
FSC05_RS10865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSC05_RS10880	COG2801	Transposase and inactivated derivatives
FSC05_RS10885	COG2801	Transposase and inactivated derivatives
FSC05_RS10890	COG2801	Transposase and inactivated derivatives
FSC05_RS10910	COG0628	permease
FSC05_RS10920	COG2824	Alkylphosphonate utilization operon protein PhnA
FSC05_RS10925	COG3189	MarR family transcriptional regulator
FSC05_RS10940	COG0564	pseudouridine synthase activity
FSC05_RS10985	COG0354	folic acid binding
FSC05_RS11015	COG0363	glucosamine-6-phosphate deaminase activity
FSC05_RS11025	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FSC05_RS11030	COG1877	trehalose-phosphatase activity
FSC05_RS11040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC05_RS11045	COG1970	mechanosensitive ion channel activity
FSC05_RS11055	COG2233	PERMEase
FSC05_RS11065	COG0833	amino acid
FSC05_RS11085	COG0183	Belongs to the thiolase family
FSC05_RS11100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_RS11110	COG2207	Transcriptional regulator
FSC05_RS11115	COG0183	Belongs to the thiolase family
FSC05_RS11120	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC05_RS11120	COG1024	Enoyl-CoA hydratase
FSC05_RS11145	COG1272	protein, Hemolysin III
FSC05_RS11150	COG0477	Major facilitator Superfamily
FSC05_RS11160	COG1408	metallophosphoesterase
FSC05_RS11165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC05_RS11175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSC05_RS11210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC05_RS11215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC05_RS11220	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FSC05_RS11230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSC05_RS11235	COG0625	glutathione transferase activity
FSC05_RS11240	COG2969	positive regulation of protein catabolic process
FSC05_RS11290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC05_RS11335	COG0037	tRNA processing
FSC05_RS11345	COG0248	Ppx GppA phosphatase
FSC05_RS11370	COG0072	phenylalanine-tRNA ligase activity
FSC05_RS11405	COG1238	metal cluster binding
FSC05_RS11410	COG0625	glutathione transferase activity
FSC05_RS11435	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_RS11440	COG3028	Belongs to the UPF0307 family
FSC05_RS11450	COG1660	Displays ATPase and GTPase activities
FSC05_RS11465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSC05_RS11470	COG0617	tRNA 3'-terminal CCA addition
FSC05_RS11475	COG1555	photosystem II stabilization
FSC05_RS11480	COG3956	TIGRFAM MazG family protein
FSC05_RS11495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC05_RS11505	COG0124	histidyl-tRNA synthetase
FSC05_RS11535	COG2975	iron-sulfur cluster assembly
FSC05_RS11575	COG0440	acetolactate synthase activity
FSC05_RS11580	COG0028	Belongs to the TPP enzyme family
FSC05_RS11605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_RS11610	COG0577	efflux transmembrane transporter activity
FSC05_RS11610	COG1136	(ABC) transporter
FSC05_RS11640	COG3209	COG3209 Rhs family protein
FSC05_RS11660	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSC05_RS11665	COG1162	GTPase activity
FSC05_RS11675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FSC05_RS11685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSC05_RS11695	COG3781	membrane
FSC05_RS11710	COG2350	Protein conserved in bacteria
FSC05_RS11730	COG1666	GTP binding
FSC05_RS11740	COG1607	acyl-coa hydrolase
FSC05_RS11800	COG1183	phosphatidylcholine synthase activity
FSC05_RS11805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FSC05_RS11845	COG1196	nuclear chromosome segregation
FSC05_RS11845	COG0741	lytic transglycosylase activity
FSC05_RS11845	COG0739	heme binding
FSC05_RS11855	COG1702	phosphate starvation-inducible protein PhoH
FSC05_RS11905	COG1295	ribonuclease BN
FSC05_RS11935	COG0788	formyltetrahydrofolate deformylase activity
FSC05_RS11960	COG4651	solute:proton antiporter activity
FSC05_RS11960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSC05_RS11975	COG0724	RNA recognition motif
FSC05_RS11980	COG0210	DNA helicase
FSC05_RS11990	COG1929	Belongs to the glycerate kinase type-1 family
FSC05_RS12020	COG2900	Belongs to the SlyX family
FSC05_RS12030	COG1560	Kdo2-lipid A biosynthetic process
FSC05_RS12085	COG0473	3-isopropylmalate dehydrogenase activity
FSC05_RS12100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSC05_RS12115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSC05_RS12130	COG0494	nUDIX hydrolase
FSC05_RS12150	COG1960	acyl-CoA dehydrogenase activity
FSC05_RS12175	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC05_RS12180	COG3384	dioxygenase
FSC05_RS12185	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_RS12200	COG4638	Rieske (2fe-2S)
FSC05_RS12205	COG0583	DNA-binding transcription factor activity
FSC05_RS12230	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSC05_RS12235	COG3971	2-oxopent-4-enoate hydratase activity
FSC05_RS12240	COG0546	phosphoglycolate phosphatase activity
FSC05_RS12250	COG1530	ribonuclease E activity
FSC05_RS12255	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_RS12280	COG1983	PspC domain protein
FSC05_RS12285	COG0617	tRNA 3'-terminal CCA addition
FSC05_RS12285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSC05_RS12285	COG0517	IMP dehydrogenase activity
FSC05_RS12295	COG0751	glycine-tRNA ligase activity
FSC05_RS12325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC05_RS12350	COG0493	'glutamate synthase
FSC05_RS12350	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC05_RS12360	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FSC05_RS12370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC05_RS12385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSC05_RS12395	COG0644	oxidoreductase
FSC05_RS12395	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSC05_RS12400	COG3293	Transposase
FSC05_RS12435	COG2801	Transposase and inactivated derivatives
FSC05_RS12460	COG3501	Rhs element vgr protein
FSC05_RS12465	COG0425	Belongs to the sulfur carrier protein TusA family
FSC05_RS12470	COG4535	Mg2 and Co2 transporter CorC
FSC05_RS12475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSC05_RS12495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSC05_RS12505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSC05_RS12515	COG0789	Transcriptional regulator
FSC05_RS12520	COG2841	Protein conserved in bacteria
FSC05_RS12535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSC05_RS12540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC05_RS12545	COG1074	ATP-dependent DNA helicase activity
FSC05_RS12550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSC05_RS12580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC05_RS12590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSC05_RS12605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC05_RS12605	COG2111	Na H antiporter
FSC05_RS12610	COG1006	Multisubunit Na H antiporter MnhC subunit
FSC05_RS12615	COG0651	ATP synthesis coupled electron transport
FSC05_RS12625	COG2212	antiporter activity
FSC05_RS12635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSC05_RS12645	COG0195	Participates in both transcription termination and antitermination
FSC05_RS12650	COG0779	Required for maturation of 30S ribosomal subunits
FSC05_RS12700	COG0237	dephospho-CoA kinase activity
FSC05_RS12710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC05_RS12715	COG3123	guanosine phosphorylase activity
FSC05_RS12720	COG0497	DNA recombination
FSC05_RS12730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSC05_RS12745	COG1132	(ABC) transporter
FSC05_RS12750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSC05_RS12785	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC05_RS12785	COG1024	Enoyl-CoA hydratase
FSC05_RS12795	COG2233	PERMEase
FSC05_RS12805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSC05_RS12830	COG0326	Molecular chaperone. Has ATPase activity
FSC05_RS12845	COG2056	Na+-H+ antiporter family
FSC05_RS12865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSC05_RS12870	COG0085	RNA polymerase activity
FSC05_RS12885	COG0081	regulation of translation
FSC05_RS12970	COG0824	Thioesterase
FSC05_RS12990	COG0181	hydroxymethylbilane synthase activity
FSC05_RS13000	COG3275	phosphorelay sensor kinase activity
FSC05_RS13035	COG0494	nUDIX hydrolase
FSC05_RS13040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSC05_RS13045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSC05_RS13050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC05_RS13060	COG0772	Belongs to the SEDS family
FSC05_RS13065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSC05_RS13085	COG4974	Belongs to the 'phage' integrase family
FSC05_RS13100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSC05_RS13110	COG2197	response regulator
FSC05_RS13125	COG0793	Belongs to the peptidase S41A family
FSC05_RS13130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSC05_RS13135	COG0795	lipopolysaccharide-transporting ATPase activity
FSC05_RS13140	COG0795	lipopolysaccharide-transporting ATPase activity
FSC05_RS13165	COG0586	Pfam SNARE associated Golgi protein
FSC05_RS13180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC05_RS13180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC05_RS13190	COG0004	ammonium transporteR
FSC05_RS13195	COG0347	Belongs to the P(II) protein family
FSC05_RS13205	COG0606	chelatase, subunit chli
FSC05_RS13220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSC05_RS13235	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_RS13245	COG0477	Major facilitator Superfamily
FSC05_RS13250	COG2860	membrane
FSC05_RS13260	COG1253	flavin adenine dinucleotide binding
FSC05_RS13280	COG2814	Major facilitator Superfamily
FSC05_RS13295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC05_RS13315	COG2814	Major facilitator Superfamily
FSC05_RS13365	COG0758	DNA mediated transformation
FSC05_RS13375	COG0697	spore germination
FSC05_RS13380	COG0386	Belongs to the glutathione peroxidase family
FSC05_RS13405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSC05_RS13455	COG1121	(ABC) transporter
FSC05_RS13460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSC05_RS13470	COG2837	iron assimilation
FSC05_RS13490	COG3501	Rhs element vgr protein
FSC05_RS13495	COG0281	malic enzyme
FSC05_RS13535	COG1715	Restriction endonuclease
FSC05_RS13540	COG2826	transposase and inactivated derivatives, IS30 family
FSC05_RS13545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC05_RS13545	COG0519	Catalyzes the synthesis of GMP from XMP
FSC05_RS13550	COG2259	Doxx family
FSC05_RS13555	COG0586	Pfam SNARE associated Golgi protein
FSC05_RS13570	COG1192	Involved in chromosome partitioning
FSC05_RS13580	COG0271	Belongs to the BolA IbaG family
FSC05_RS13615	COG3756	Protein conserved in bacteria
FSC05_RS13635	COG3586	endonuclease activity
FSC05_RS13680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC05_RS13685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC05_RS13700	COG1570	exodeoxyribonuclease VII activity
FSC05_RS13765	COG1570	exodeoxyribonuclease VII activity
FSC05_RS13795	COG2801	Transposase and inactivated derivatives
FSC05_RS13800	COG2801	Transposase and inactivated derivatives
FSC05_RS13815	COG2801	Transposase and inactivated derivatives
FSC05_RS13855	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FSC05_RS13870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FSC05_RS13880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSC05_RS13930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC05_RS13945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSC05_RS13955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSC05_RS13965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC05_RS13970	COG0438	transferase activity, transferring glycosyl groups
FSC05_RS13980	COG0438	transferase activity, transferring glycosyl groups
FSC05_RS13985	COG1215	transferase activity, transferring glycosyl groups
FSC05_RS13995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FSC05_RS13995	COG1215	transferase activity, transferring glycosyl groups
FSC05_RS14000	COG0438	transferase activity, transferring glycosyl groups
FSC05_RS14005	COG1216	Glycosyl transferase, family 2
FSC05_RS14005	COG1442	glycosyl transferase family 8
FSC05_RS14010	COG5039	Polysaccharide pyruvyl transferase
FSC05_RS14075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_RS14080	COG1309	transcriptional regulator
FSC05_RS14090	COG2233	PERMEase
FSC05_RS14105	COG0129	dihydroxy-acid dehydratase activity
FSC05_RS14120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSC05_RS14125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSC05_RS14135	COG0733	neurotransmitter:sodium symporter activity
FSC05_RS14140	COG1012	belongs to the aldehyde dehydrogenase family
FSC05_RS14160	COG2814	Major facilitator Superfamily
FSC05_RS14190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSC05_RS14235	COG2951	lytic endotransglycosylase activity
FSC05_RS14245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSC05_RS14265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC05_RS14280	COG2388	GCN5-related N-acetyl-transferase
FSC05_RS14290	COG0861	Integral membrane protein TerC family
FSC05_RS14295	COG0402	S-adenosylhomocysteine deaminase activity
FSC05_RS14310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC05_RS14315	COG1230	cation diffusion facilitator family transporter
FSC05_RS14340	COG0706	membrane insertase activity
FSC05_RS14345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSC05_RS14350	COG0594	ribonuclease P activity
FSC05_RS14400	COG1192	Involved in chromosome partitioning
FSC05_RS14500	COG0582	viral genome integration into host DNA
FSC05_RS14515	COG1230	cation diffusion facilitator family transporter
FSC05_RS14550	COG1683	Conserved Protein
FSC05_RS14600	COG4974	Belongs to the 'phage' integrase family
FSC05_RS14695	COG1373	ATPase (AAA superfamily
FSC05_RS14775	COG0673	inositol 2-dehydrogenase activity
FSC05_RS14795	COG2826	transposase and inactivated derivatives, IS30 family
FSC05_RS14815	COG1660	Displays ATPase and GTPase activities
FSC05_RS14870	COG2801	Transposase and inactivated derivatives
FSC05_RS14875	COG2801	Transposase and inactivated derivatives
FSC05_RS14895	COG2963	transposase activity
FSC05_RS15015	COG2801	Transposase and inactivated derivatives
FSC05_RS15020	COG2801	Transposase and inactivated derivatives
FSC05_RS15025	COG3657	addiction module killer protein
FSC05_RS15030	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC05_RS15045	COG3188	usher protein
FSC05_RS15065	COG2801	Transposase and inactivated derivatives
FSC05_RS15080	COG0270	DNA (cytosine-5-)-methyltransferase activity
FSC05_RS15180	COG0488	(ABC) transporter
FSC05_RS15185	COG0300	oxidoreductase activity