locus-tag	class	description
CTZ23_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTZ23_RS00010	COG0592	DNA-directed DNA polymerase activity
CTZ23_RS00020	COG0187	DNA topoisomerase II activity
CTZ23_RS00025	COG1063	alcohol dehydrogenase
CTZ23_RS00030	COG3328	transposase activity
CTZ23_RS00035	COG0488	(ABC) transporter
CTZ23_RS00060	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ23_RS00065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ23_RS00080	COG0737	Belongs to the 5'-nucleotidase family
CTZ23_RS00110	COG2814	Major facilitator Superfamily
CTZ23_RS00115	COG2133	pyrroloquinoline quinone binding
CTZ23_RS00125	COG1047	Peptidyl-prolyl cis-trans
CTZ23_RS00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CTZ23_RS00135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ23_RS00140	COG0196	riboflavin kinase activity
CTZ23_RS00150	COG1309	transcriptional regulator
CTZ23_RS00155	COG1116	anion transmembrane transporter activity
CTZ23_RS00160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ23_RS00165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ23_RS00170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_RS00175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_RS00180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTZ23_RS00180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CTZ23_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS00205	COG0546	phosphoglycolate phosphatase activity
CTZ23_RS00210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ23_RS00220	COG1309	transcriptional regulator
CTZ23_RS00225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CTZ23_RS00235	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ23_RS00255	COG1064	alcohol dehydrogenase
CTZ23_RS00260	COG2818	Glycosylase
CTZ23_RS00270	COG0739	heme binding
CTZ23_RS00275	COG1194	a g-specific adenine glycosylase
CTZ23_RS00290	COG5487	UPF0391 membrane protein
CTZ23_RS00295	COG2983	Belongs to the UPF0260 family
CTZ23_RS00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ23_RS00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CTZ23_RS00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ23_RS00325	COG1335	isochorismatase
CTZ23_RS00330	COG0385	Bile acid
CTZ23_RS00345	COG3830	Belongs to the UPF0237 family
CTZ23_RS00345	COG0560	Phosphoserine phosphatase
CTZ23_RS00365	COG0753	catalase activity
CTZ23_RS00410	COG0534	Mate efflux family protein
CTZ23_RS00415	COG0436	Aminotransferase
CTZ23_RS00420	COG2733	membrane
CTZ23_RS00435	COG2918	glutathione biosynthetic process
CTZ23_RS00440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CTZ23_RS00450	COG3150	esterase
CTZ23_RS00490	COG0471	metal ion transport
CTZ23_RS00500	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ23_RS00505	COG4266	Belongs to the allantoicase family
CTZ23_RS00510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_RS00515	COG1247	-acetyltransferase
CTZ23_RS00555	COG0625	glutathione transferase activity
CTZ23_RS00560	COG3706	GGDEF domain
CTZ23_RS00565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ23_RS00580	COG1393	Belongs to the ArsC family
CTZ23_RS00585	COG0708	Exodeoxyribonuclease III
CTZ23_RS00610	COG0189	ligase activity
CTZ23_RS00615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTZ23_RS00620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ23_RS00630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ23_RS00640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ23_RS00670	COG2119	membrane
CTZ23_RS00675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_RS00675	COG0426	domain, Protein
CTZ23_RS00700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ23_RS00725	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS00730	COG1519	Transferase
CTZ23_RS00735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ23_RS00740	COG0668	transmembrane transport
CTZ23_RS00745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ23_RS00760	COG0431	NADPH-dependent FMN reductase
CTZ23_RS00775	COG2205	protein histidine kinase activity
CTZ23_RS00775	COG0784	Response regulator, receiver
CTZ23_RS00780	COG3162	membrane
CTZ23_RS00785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_RS00805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ23_RS00830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ23_RS00835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ23_RS00855	COG2814	Major facilitator Superfamily
CTZ23_RS00860	COG0629	single-stranded DNA binding
CTZ23_RS00900	COG2801	Transposase and inactivated derivatives
CTZ23_RS00920	COG2801	Transposase and inactivated derivatives
CTZ23_RS00960	COG2205	protein histidine kinase activity
CTZ23_RS00965	COG3174	membrane
CTZ23_RS00970	COG2217	Heavy metal translocating P-type atpase
CTZ23_RS01080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ23_RS01140	COG2132	Multicopper oxidase
CTZ23_RS01155	COG3077	Addiction module antitoxin, RelB DinJ family
CTZ23_RS01200	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CTZ23_RS01225	COG3158	transport of potassium into the cell
CTZ23_RS01265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ23_RS01280	COG0697	spore germination
CTZ23_RS01300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ23_RS01330	COG0427	acetyl-CoA hydrolase
CTZ23_RS01360	COG4221	oxidoreductase activity
CTZ23_RS01380	COG0488	(ABC) transporter
CTZ23_RS01400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ23_RS01410	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ23_RS01415	COG0275	rRNA processing
CTZ23_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ23_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ23_RS01445	COG2226	methyltransferase
CTZ23_RS01450	COG3385	transposase activity
CTZ23_RS01500	COG0070	glutamate synthase
CTZ23_RS01500	COG0069	glutamate synthase activity
CTZ23_RS01500	COG0067	glutamate synthase
CTZ23_RS01505	COG0493	'glutamate synthase
CTZ23_RS01515	COG1704	LemA family
CTZ23_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ23_RS01530	COG4969	Belongs to the N-Me-Phe pilin family
CTZ23_RS01535	COG3307	-O-antigen
CTZ23_RS01545	COG3307	-O-antigen
CTZ23_RS01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_RS01570	COG1758	RNA polymerase activity
CTZ23_RS01575	COG0194	GDP metabolic process
CTZ23_RS01620	COG0228	four-way junction DNA binding
CTZ23_RS01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ23_RS01635	COG0335	large ribosomal subunit rRNA binding
CTZ23_RS01640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ23_RS01645	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ23_RS01650	COG5380	lipid catabolic process
CTZ23_RS01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ23_RS01685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ23_RS01690	COG0277	FAD linked oxidase domain protein
CTZ23_RS01705	COG2814	Major facilitator Superfamily
CTZ23_RS01715	COG0628	permease
CTZ23_RS01720	COG1192	Involved in chromosome partitioning
CTZ23_RS01735	COG2226	methyltransferase
CTZ23_RS01755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CTZ23_RS01760	COG0254	rRNA binding
CTZ23_RS01765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ23_RS01770	COG0534	Mate efflux family protein
CTZ23_RS01780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ23_RS01785	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS01800	COG0408	coproporphyrinogen oxidase activity
CTZ23_RS01805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ23_RS01830	COG1127	ABC transporter
CTZ23_RS01835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ23_RS01840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTZ23_RS01845	COG2854	intermembrane phospholipid transfer
CTZ23_RS01855	COG0598	Magnesium transport protein CorA
CTZ23_RS01870	COG1040	competence protein
CTZ23_RS01875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ23_RS01890	COG2937	Belongs to the GPAT DAPAT family
CTZ23_RS01895	COG1946	Acyl-CoA thioesterase
CTZ23_RS01900	COG1301	dicarboxylic acid transport
CTZ23_RS01920	COG1959	2 iron, 2 sulfur cluster binding
CTZ23_RS01930	COG0433	COG0433 Predicted ATPase
CTZ23_RS01955	COG0088	Forms part of the polypeptide exit tunnel
CTZ23_RS01985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CTZ23_RS02020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CTZ23_RS02025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CTZ23_RS02035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CTZ23_RS02070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CTZ23_RS02075	COG0202	RNA polymerase activity
CTZ23_RS02085	COG2072	flavoprotein involved in K transport
CTZ23_RS02090	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS02095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ23_RS02130	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ23_RS02135	COG0339	signal peptide processing
CTZ23_RS02145	COG0557	exoribonuclease II activity
CTZ23_RS02180	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ23_RS02230	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CTZ23_RS02240	COG3040	lipid binding
CTZ23_RS02300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS02300	COG2813	Specifically methylates the guanine in position
CTZ23_RS02305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS02310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ23_RS02320	COG3128	pkhd-type hydroxylase
CTZ23_RS02325	COG4774	siderophore transport
CTZ23_RS02330	COG4771	TonB-dependent receptor
CTZ23_RS02340	COG0740	serine-type endopeptidase activity
CTZ23_RS02355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ23_RS02355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ23_RS02365	COG0280	phosphate acetyltransferase
CTZ23_RS02365	COG0857	belongs to the CobB CobQ family
CTZ23_RS02370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ23_RS02400	COG0793	Belongs to the peptidase S41A family
CTZ23_RS02430	COG3046	protein related to deoxyribodipyrimidine photolyase
CTZ23_RS02460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ23_RS02475	COG0642	Histidine kinase
CTZ23_RS02480	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS02510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ23_RS02535	COG4221	oxidoreductase activity
CTZ23_RS02540	COG0583	DNA-binding transcription factor activity
CTZ23_RS02545	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ23_RS02550	COG3321	synthase
CTZ23_RS02550	COG0604	alcohol dehydrogenase
CTZ23_RS02565	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CTZ23_RS02580	COG1979	alcohol dehydrogenase
CTZ23_RS02590	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS02600	COG1309	transcriptional regulator
CTZ23_RS02605	COG2130	NADP-dependent
CTZ23_RS02675	COG2801	Transposase and inactivated derivatives
CTZ23_RS02680	COG2862	Uncharacterized protein family, UPF0114
CTZ23_RS02710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ23_RS02725	COG0084	hydrolase, TatD family'
CTZ23_RS02730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ23_RS02735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ23_RS02800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_RS02870	COG2814	Major facilitator Superfamily
CTZ23_RS02875	COG0697	spore germination
CTZ23_RS02900	COG3622	Belongs to the hyi family
CTZ23_RS02910	COG1024	Enoyl-CoA hydratase
CTZ23_RS02915	COG5002	protein histidine kinase activity
CTZ23_RS02915	COG0784	Response regulator, receiver
CTZ23_RS02915	COG2205	protein histidine kinase activity
CTZ23_RS02925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ23_RS02940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_RS02960	COG1862	Preprotein translocase
CTZ23_RS02975	COG3706	GGDEF domain
CTZ23_RS02975	COG2203	Gaf domain
CTZ23_RS02975	COG5001	Diguanylate cyclase
CTZ23_RS02975	COG4251	negative regulation of phosphorylation
CTZ23_RS02980	COG1704	LemA family
CTZ23_RS02990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CTZ23_RS03010	COG5002	protein histidine kinase activity
CTZ23_RS03015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ23_RS03035	COG0463	Glycosyl transferase, family 2
CTZ23_RS03070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CTZ23_RS03110	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS03115	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS03130	COG2205	protein histidine kinase activity
CTZ23_RS03135	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS03145	COG2315	Protein conserved in bacteria
CTZ23_RS03150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ23_RS03170	COG2096	Adenosyltransferase
CTZ23_RS03175	COG4206	TonB-dependent receptor
CTZ23_RS03220	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CTZ23_RS03225	COG0285	dihydrofolate synthase activity
CTZ23_RS03240	COG0450	alkyl hydroperoxide reductase
CTZ23_RS03255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ23_RS03260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ23_RS03285	COG2885	chlorophyll binding
CTZ23_RS03345	COG2969	positive regulation of protein catabolic process
CTZ23_RS03350	COG0625	glutathione transferase activity
CTZ23_RS03355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ23_RS03365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTZ23_RS03370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ23_RS03375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ23_RS03405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ23_RS03415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ23_RS03425	COG1408	metallophosphoesterase
CTZ23_RS03435	COG0477	Major facilitator Superfamily
CTZ23_RS03440	COG1272	protein, Hemolysin III
CTZ23_RS03465	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_RS03465	COG1024	Enoyl-CoA hydratase
CTZ23_RS03470	COG0183	Belongs to the thiolase family
CTZ23_RS03475	COG2207	Transcriptional regulator
CTZ23_RS03480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ23_RS03485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS03500	COG0183	Belongs to the thiolase family
CTZ23_RS03520	COG0833	amino acid
CTZ23_RS03530	COG2233	PERMEase
CTZ23_RS03535	COG1217	gtp-binding protein TYPA
CTZ23_RS03540	COG1970	mechanosensitive ion channel activity
CTZ23_RS03555	COG1877	trehalose-phosphatase activity
CTZ23_RS03560	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ23_RS03570	COG0363	glucosamine-6-phosphate deaminase activity
CTZ23_RS03600	COG0354	folic acid binding
CTZ23_RS03620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ23_RS03625	COG0154	amidase activity
CTZ23_RS03630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ23_RS03635	COG1077	Cell shape determining protein MreB Mrl
CTZ23_RS03640	COG1792	Involved in formation and maintenance of cell shape
CTZ23_RS03645	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ23_RS03650	COG0424	maF-like protein
CTZ23_RS03655	COG1530	ribonuclease E activity
CTZ23_RS03660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ23_RS03700	COG0625	glutathione transferase activity
CTZ23_RS03720	COG1113	amino acid transport
CTZ23_RS03725	COG2828	Protein conserved in bacteria
CTZ23_RS03730	COG0142	geranyltranstransferase activity
CTZ23_RS03740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_RS03760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ23_RS03770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CTZ23_RS03775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_RS03780	COG0839	Belongs to the complex I subunit 6 family
CTZ23_RS03785	COG0713	ATP synthesis coupled electron transport
CTZ23_RS03790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ23_RS03795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_RS03810	COG1278	Cold shock
CTZ23_RS03815	COG0583	DNA-binding transcription factor activity
CTZ23_RS03820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_RS03840	COG0668	transmembrane transport
CTZ23_RS03850	COG2081	HI0933 family
CTZ23_RS03870	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ23_RS03885	COG0004	ammonium transporteR
CTZ23_RS03910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ23_RS03910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ23_RS03915	COG0489	protein tyrosine kinase activity
CTZ23_RS03930	COG2358	TRAP transporter, solute receptor (TAXI family
CTZ23_RS03965	COG0442	prolyl-tRNA aminoacylation
CTZ23_RS04000	COG0840	transmembrane signaling receptor activity
CTZ23_RS04005	COG0643	Histidine kinase
CTZ23_RS04005	COG0784	Response regulator, receiver
CTZ23_RS04005	COG2198	Histidine kinase
CTZ23_RS04020	COG5510	response to toxic substance
CTZ23_RS04030	COG2832	Protein of unknown function (DUF454)
CTZ23_RS04035	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ23_RS04090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTZ23_RS04100	COG1289	transmembrane transporter activity
CTZ23_RS04105	COG2814	Major facilitator Superfamily
CTZ23_RS04120	COG0786	glutamate:sodium symporter activity
CTZ23_RS04125	COG1115	amino acid carrier protein
CTZ23_RS04130	COG2059	Chromate
CTZ23_RS04135	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ23_RS04145	COG1607	acyl-coa hydrolase
CTZ23_RS04180	COG0523	cobalamin synthesis protein
CTZ23_RS04185	COG4681	YaeQ
CTZ23_RS04195	COG2203	Gaf domain
CTZ23_RS04195	COG2199	diguanylate cyclase activity
CTZ23_RS04225	COG0477	Major facilitator Superfamily
CTZ23_RS04230	COG3706	GGDEF domain
CTZ23_RS04235	COG2066	Belongs to the glutaminase family
CTZ23_RS04240	COG2376	Dihydroxyacetone kinase
CTZ23_RS04260	COG0306	phosphate transporter
CTZ23_RS04285	COG4771	TonB-dependent receptor
CTZ23_RS04310	COG4181	ATPase activity
CTZ23_RS04315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ23_RS04325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ23_RS04335	COG0583	DNA-binding transcription factor activity
CTZ23_RS04345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS04350	COG1773	rubredoxin
CTZ23_RS04355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTZ23_RS04385	COG3118	belongs to the thioredoxin family
CTZ23_RS04405	COG1253	flavin adenine dinucleotide binding
CTZ23_RS04425	COG3015	lipoprotein NlpE involved in copper resistance
CTZ23_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS04445	COG0829	nickel cation binding
CTZ23_RS04465	COG0804	urea catabolic process
CTZ23_RS04480	COG0830	nickel cation binding
CTZ23_RS04500	COG0742	ribosomal rna small subunit methyltransferase
CTZ23_RS04505	COG0768	penicillin binding
CTZ23_RS04530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ23_RS04535	COG2878	Part of a membrane complex involved in electron transport
CTZ23_RS04540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ23_RS04550	COG3384	dioxygenase
CTZ23_RS04560	COG2234	aminopeptidase activity
CTZ23_RS04570	COG0675	Transposase, IS605 OrfB family
CTZ23_RS04575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ23_RS04595	COG2186	Transcriptional regulator
CTZ23_RS04605	COG0277	FAD linked oxidase domain protein
CTZ23_RS04640	COG3079	Belongs to the UPF0149 family
CTZ23_RS04645	COG0006	proline dipeptidase activity
CTZ23_RS04655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_RS04660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_RS04695	COG2816	NAD+ diphosphatase activity
CTZ23_RS04710	COG0741	lytic transglycosylase activity
CTZ23_RS04710	COG1388	LysM domain
CTZ23_RS04715	COG4166	transmembrane transport
CTZ23_RS04720	COG4174	ABC transporter (Permease)
CTZ23_RS04725	COG4239	(ABC) transporter, permease
CTZ23_RS04730	COG4172	Belongs to the ABC transporter superfamily
CTZ23_RS04755	COG0833	amino acid
CTZ23_RS04775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ23_RS04780	COG0418	dihydroorotase activity
CTZ23_RS04785	COG2203	Gaf domain
CTZ23_RS04785	COG3706	GGDEF domain
CTZ23_RS04785	COG5001	Diguanylate cyclase
CTZ23_RS04785	COG4251	negative regulation of phosphorylation
CTZ23_RS04800	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS04800	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ23_RS04815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ23_RS04865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ23_RS04870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ23_RS04890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ23_RS04895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ23_RS04900	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ23_RS04940	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS04950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ23_RS04960	COG2175	clavaminate synthase activity
CTZ23_RS04980	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ23_RS05010	COG2951	lytic endotransglycosylase activity
CTZ23_RS05025	COG0842	Transport permease protein
CTZ23_RS05030	COG1131	(ABC) transporter
CTZ23_RS05090	COG3385	transposase activity
CTZ23_RS05095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ23_RS05115	COG3634	alkyl hydroperoxide reductase activity
CTZ23_RS05120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_RS05125	COG0826	peptidase U32
CTZ23_RS05135	COG0640	Transcriptional regulator
CTZ23_RS05145	COG0798	PFAM Bile acid sodium symporter
CTZ23_RS05150	COG0431	NADPH-dependent FMN reductase
CTZ23_RS05155	COG0789	Transcriptional regulator
CTZ23_RS05170	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ23_RS05180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTZ23_RS05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ23_RS05220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ23_RS05225	COG3139	Protein of unknown function (DUF1315)
CTZ23_RS05235	COG1301	dicarboxylic acid transport
CTZ23_RS05240	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS05245	COG0693	protein deglycase activity
CTZ23_RS05255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTZ23_RS05260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ23_RS05280	COG0415	Belongs to the DNA photolyase family
CTZ23_RS05285	COG1047	Peptidyl-prolyl cis-trans
CTZ23_RS05290	COG1252	NADH dehydrogenase
CTZ23_RS05295	COG1686	Belongs to the peptidase S11 family
CTZ23_RS05310	COG1187	pseudouridine synthase activity
CTZ23_RS05320	COG0739	heme binding
CTZ23_RS05335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_RS05345	COG0612	Peptidase, M16
CTZ23_RS05355	COG3385	transposase activity
CTZ23_RS05385	COG0352	thiamine-phosphate diphosphorylase activity
CTZ23_RS05400	COG3328	transposase activity
CTZ23_RS05470	COG0596	Alpha beta hydrolase
CTZ23_RS05475	COG1309	transcriptional regulator
CTZ23_RS05540	COG1278	Cold shock
CTZ23_RS05555	COG2070	2-Nitropropane dioxygenase
CTZ23_RS05580	COG2391	methyltransferase activity
CTZ23_RS05590	COG3634	alkyl hydroperoxide reductase activity
CTZ23_RS05620	COG1643	Atp-dependent helicase
CTZ23_RS05645	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ23_RS05645	COG0517	IMP dehydrogenase activity
CTZ23_RS05650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ23_RS05660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ23_RS05665	COG1137	ATPase activity
CTZ23_RS05700	COG4122	O-methyltransferase activity
CTZ23_RS05710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ23_RS05750	COG2011	ABC-type metal ion transport system permease component
CTZ23_RS05755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ23_RS05785	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ23_RS05825	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ23_RS05835	COG1305	Transglutaminase-like
CTZ23_RS05850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ23_RS05865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTZ23_RS05870	COG0360	Binds together with S18 to 16S ribosomal RNA
CTZ23_RS05880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ23_RS05885	COG1845	cytochrome c oxidase, subunit III
CTZ23_RS05890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ23_RS05895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ23_RS05920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ23_RS05940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CTZ23_RS05950	COG3781	membrane
CTZ23_RS05970	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS05975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ23_RS05985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTZ23_RS05995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTZ23_RS06010	COG0477	Major facilitator Superfamily
CTZ23_RS06080	COG0308	aminopeptidase N
CTZ23_RS06090	COG0589	response to stress
CTZ23_RS06095	COG0589	response to stress
CTZ23_RS06105	COG3135	benzoate transporter
CTZ23_RS06115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTZ23_RS06130	COG0183	Belongs to the thiolase family
CTZ23_RS06140	COG2030	dehydratase
CTZ23_RS06145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ23_RS06160	COG0824	Thioesterase
CTZ23_RS06165	COG1454	alcohol dehydrogenase
CTZ23_RS06170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ23_RS06190	COG0069	glutamate synthase activity
CTZ23_RS06200	COG4585	Histidine kinase
CTZ23_RS06205	COG2850	peptidyl-arginine hydroxylation
CTZ23_RS06210	COG0424	maF-like protein
CTZ23_RS06235	COG0697	spore germination
CTZ23_RS06275	COG3698	Phosphodiester glycosidase
CTZ23_RS06295	COG0506	proline dehydrogenase activity
CTZ23_RS06295	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ23_RS06295	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ23_RS06305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_RS06310	COG1027	Aspartate ammonia-lyase
CTZ23_RS06315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ23_RS06320	COG0583	DNA-binding transcription factor activity
CTZ23_RS06325	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS06330	COG2814	Major facilitator Superfamily
CTZ23_RS06335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ23_RS06350	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ23_RS06350	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS06385	COG0148	phosphopyruvate hydratase activity
CTZ23_RS06400	COG0772	Belongs to the SEDS family
CTZ23_RS06415	COG2137	regulation of response to DNA damage stimulus
CTZ23_RS06425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ23_RS06430	COG1011	Hydrolase
CTZ23_RS06445	COG0268	Binds directly to 16S ribosomal RNA
CTZ23_RS06450	COG0702	epimerase
CTZ23_RS06455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ23_RS06470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ23_RS06500	COG0316	Belongs to the HesB IscA family
CTZ23_RS06505	COG0822	iron-sulfur transferase activity
CTZ23_RS06535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_RS06590	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ23_RS06610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ23_RS06625	COG0517	IMP dehydrogenase activity
CTZ23_RS06625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTZ23_RS06625	COG0617	tRNA 3'-terminal CCA addition
CTZ23_RS06655	COG0612	Peptidase, M16
CTZ23_RS06660	COG0552	protein localization to endoplasmic reticulum
CTZ23_RS06705	COG0693	protein deglycase activity
CTZ23_RS06715	COG1283	sodium-dependent phosphate transmembrane transporter activity
CTZ23_RS06725	COG1346	cytolysis
CTZ23_RS06735	COG0583	DNA-binding transcription factor activity
CTZ23_RS06755	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTZ23_RS06765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ23_RS06770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ23_RS06775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ23_RS06800	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS06805	COG2207	Transcriptional regulator
CTZ23_RS06810	COG2814	Major facilitator Superfamily
CTZ23_RS06820	COG1271	oxidase subunit
CTZ23_RS06825	COG1294	oxidase, subunit
CTZ23_RS06835	COG1525	nuclease
CTZ23_RS06885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ23_RS06890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ23_RS06905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ23_RS06915	COG2814	Major facilitator Superfamily
CTZ23_RS06935	COG1132	(ABC) transporter
CTZ23_RS06945	COG0668	transmembrane transport
CTZ23_RS06950	COG3122	Protein conserved in bacteria
CTZ23_RS06970	COG0640	Transcriptional regulator
CTZ23_RS06980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ23_RS06985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_RS06985	COG1116	anion transmembrane transporter activity
CTZ23_RS06995	COG2223	nitrite transmembrane transporter activity
CTZ23_RS07000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS07005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS07010	COG0243	molybdopterin cofactor binding
CTZ23_RS07020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ23_RS07035	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ23_RS07035	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ23_RS07040	COG0303	'Molybdopterin
CTZ23_RS07050	COG4149	molybdate abc transporter
CTZ23_RS07055	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ23_RS07060	COG0583	DNA-binding transcription factor activity
CTZ23_RS07080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS07085	COG0183	Belongs to the thiolase family
CTZ23_RS07090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ23_RS07095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ23_RS07100	COG3135	benzoate transporter
CTZ23_RS07105	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS07110	COG0543	2 iron, 2 sulfur cluster binding
CTZ23_RS07110	COG0633	Ferredoxin
CTZ23_RS07115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ23_RS07120	COG4638	Rieske (2fe-2S)
CTZ23_RS07130	COG4829	muconolactone delta-isomerase
CTZ23_RS07135	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ23_RS07140	COG0583	DNA-binding transcription factor activity
CTZ23_RS07145	COG2814	Major facilitator Superfamily
CTZ23_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS07185	COG2223	nitrite transmembrane transporter activity
CTZ23_RS07195	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CTZ23_RS07200	COG2116	formate transmembrane transporter activity
CTZ23_RS07205	COG0515	serine threonine protein kinase
CTZ23_RS07220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS07265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ23_RS07270	COG1309	transcriptional regulator
CTZ23_RS07275	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_RS07290	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS07300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ23_RS07320	COG2026	Addiction module toxin, RelE StbE family
CTZ23_RS07335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTZ23_RS07340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_RS07345	COG0730	response to heat
CTZ23_RS07395	COG2801	Transposase and inactivated derivatives
CTZ23_RS07490	COG0596	Alpha beta hydrolase
CTZ23_RS07525	COG0511	ligase activity, forming carbon-carbon bonds
CTZ23_RS07530	COG0439	Biotin carboxylase
CTZ23_RS07545	COG2814	Major facilitator Superfamily
CTZ23_RS07550	COG3038	cytochrome b561
CTZ23_RS07580	COG1546	Belongs to the CinA family
CTZ23_RS07580	COG1058	Belongs to the CinA family
CTZ23_RS07590	COG0372	Belongs to the citrate synthase family
CTZ23_RS07625	COG0542	response to heat
CTZ23_RS07630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ23_RS07655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CTZ23_RS07665	COG0569	domain protein
CTZ23_RS07670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ23_RS07690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ23_RS07700	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ23_RS07715	COG1294	oxidase, subunit
CTZ23_RS07720	COG4890	Cyd operon protein YbgT
CTZ23_RS07755	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS07760	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS07780	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ23_RS07785	COG2207	Transcriptional regulator
CTZ23_RS07790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_RS07795	COG0730	response to heat
CTZ23_RS07800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ23_RS07830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_RS07840	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_RS07850	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_RS07865	COG0575	Belongs to the CDS family
CTZ23_RS07870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ23_RS07875	COG0233	cytoplasmic translational termination
CTZ23_RS07890	COG3852	Histidine kinase
CTZ23_RS07895	COG2204	response regulator
CTZ23_RS07905	COG0583	DNA-binding transcription factor activity
CTZ23_RS07935	COG1253	flavin adenine dinucleotide binding
CTZ23_RS07955	COG3385	transposase activity
CTZ23_RS07960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ23_RS07965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ23_RS07980	COG2431	L-lysine efflux transmembrane transporter activity
CTZ23_RS07995	COG0776	regulation of translation
CTZ23_RS08025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTZ23_RS08060	COG0084	hydrolase, TatD family'
CTZ23_RS08080	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ23_RS08085	COG1132	(ABC) transporter
CTZ23_RS08095	COG0811	peptide transport
CTZ23_RS08100	COG1475	DNA binding
CTZ23_RS08105	COG1192	Involved in chromosome partitioning
CTZ23_RS08115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ23_RS08120	COG3178	'Phosphotransferase
CTZ23_RS08130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_RS08135	COG1923	regulation of RNA biosynthetic process
CTZ23_RS08145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ23_RS08150	COG0802	atpase or kinase
CTZ23_RS08175	COG2707	UPF0756 membrane protein
CTZ23_RS08185	COG0583	DNA-binding transcription factor activity
CTZ23_RS08190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ23_RS08200	COG1454	alcohol dehydrogenase
CTZ23_RS08220	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ23_RS08220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ23_RS08225	COG2353	YceI-like domain
CTZ23_RS08235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ23_RS08240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CTZ23_RS08280	COG1254	Belongs to the acylphosphatase family
CTZ23_RS08285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ23_RS08285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ23_RS08290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTZ23_RS08310	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS08320	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ23_RS08325	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ23_RS08330	COG0183	Belongs to the thiolase family
CTZ23_RS08335	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_RS08340	COG1024	Enoyl-CoA hydratase
CTZ23_RS08345	COG1024	Enoyl-CoA hydratase
CTZ23_RS08350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_RS08355	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ23_RS08360	COG3396	Phenylacetate-CoA oxygenase
CTZ23_RS08365	COG3460	Phenylacetate-CoA oxygenase
CTZ23_RS08370	COG3396	Phenylacetate-CoA oxygenase
CTZ23_RS08375	COG2030	dehydratase
CTZ23_RS08375	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_RS08400	COG0783	Belongs to the Dps family
CTZ23_RS08485	COG5001	Diguanylate cyclase
CTZ23_RS08485	COG5002	protein histidine kinase activity
CTZ23_RS08495	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CTZ23_RS08515	COG4773	Receptor
CTZ23_RS08555	COG3328	transposase activity
CTZ23_RS08565	COG1401	restriction endodeoxyribonuclease activity
CTZ23_RS08575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_RS08600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_RS08605	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CTZ23_RS08650	COG2801	Transposase and inactivated derivatives
CTZ23_RS08675	COG0582	viral genome integration into host DNA
CTZ23_RS08680	COG0582	viral genome integration into host DNA
CTZ23_RS08690	COG3772	lysozyme
CTZ23_RS08770	COG3561	AntA/AntB antirepressor
CTZ23_RS08820	COG2369	cell adhesion
CTZ23_RS08825	COG3567	Phage-associated protein, HI1409 family
CTZ23_RS08830	COG5410	chromosome segregation
CTZ23_RS08850	COG2801	Transposase and inactivated derivatives
CTZ23_RS08940	COG5377	YqaJ viral recombinase family
CTZ23_RS08980	COG0204	Acyl-transferase
CTZ23_RS09005	COG0012	GTP binding
CTZ23_RS09015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ23_RS09030	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CTZ23_RS09040	COG0386	Belongs to the glutathione peroxidase family
CTZ23_RS09045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTZ23_RS09050	COG0436	Aminotransferase
CTZ23_RS09055	COG2755	lipolytic protein G-D-S-L family
CTZ23_RS09055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTZ23_RS09095	COG0515	serine threonine protein kinase
CTZ23_RS09095	COG2815	serine threonine protein kinase
CTZ23_RS09130	COG1610	YqeY-like protein
CTZ23_RS09145	COG4783	chaperone-mediated protein folding
CTZ23_RS09210	COG0513	Belongs to the DEAD box helicase family
CTZ23_RS09230	COG2363	Small membrane protein
CTZ23_RS09250	COG0659	secondary active sulfate transmembrane transporter activity
CTZ23_RS09260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ23_RS09280	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS09285	COG1309	transcriptional regulator
CTZ23_RS09290	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS09295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ23_RS09300	COG1024	Enoyl-CoA hydratase
CTZ23_RS09305	COG4770	biotin carboxylase activity
CTZ23_RS09320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ23_RS09335	COG0540	Belongs to the ATCase OTCase family
CTZ23_RS09355	COG1765	OsmC-like protein
CTZ23_RS09365	COG0667	Aldo Keto reductase
CTZ23_RS09380	COG0501	Belongs to the peptidase M48B family
CTZ23_RS09385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ23_RS09405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ23_RS09415	COG0527	aspartate kinase activity
CTZ23_RS09425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ23_RS09435	COG1215	transferase activity, transferring glycosyl groups
CTZ23_RS09445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ23_RS09450	COG2252	PERMEase
CTZ23_RS09485	COG0714	Associated with various cellular activities
CTZ23_RS09490	COG2879	small protein
CTZ23_RS09500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CTZ23_RS09505	COG1509	lysine 2,3-aminomutase activity
CTZ23_RS09540	COG1067	ATP-dependent peptidase activity
CTZ23_RS09545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ23_RS09550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ23_RS09555	COG0583	DNA-binding transcription factor activity
CTZ23_RS09565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ23_RS09580	COG1686	Belongs to the peptidase S11 family
CTZ23_RS09585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ23_RS09590	COG3328	transposase activity
CTZ23_RS09595	COG1280	lysine exporter protein (LysE YggA)
CTZ23_RS09625	COG0616	signal peptide processing
CTZ23_RS09635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ23_RS09645	COG0573	inorganic phosphate transmembrane transporter activity
CTZ23_RS09655	COG0076	glutamate decarboxylase activity
CTZ23_RS09660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ23_RS09670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CTZ23_RS09695	COG1733	regulation of RNA biosynthetic process
CTZ23_RS09700	COG0702	epimerase
CTZ23_RS09730	COG0556	nucleotide-excision repair
CTZ23_RS09740	COG3706	GGDEF domain
CTZ23_RS09750	COG0436	Aminotransferase
CTZ23_RS09775	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ23_RS09780	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ23_RS09790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ23_RS09795	COG0571	ribonuclease III activity
CTZ23_RS09805	COG0681	Belongs to the peptidase S26 family
CTZ23_RS09820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ23_RS09830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ23_RS09845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ23_RS09855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ23_RS09870	COG4208	sulfate ABC transporter
CTZ23_RS09875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ23_RS09880	COG0583	DNA-binding transcription factor activity
CTZ23_RS09890	COG4625	pathogenesis
CTZ23_RS09900	COG0602	queuosine metabolic process
CTZ23_RS09905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ23_RS09915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ23_RS09935	COG0583	DNA-binding transcription factor activity
CTZ23_RS09945	COG1051	belongs to the nudix hydrolase family
CTZ23_RS09945	COG1056	cytidyltransferase-related domain
CTZ23_RS09950	COG1024	Enoyl-CoA hydratase
CTZ23_RS09955	COG0778	Nitroreductase
CTZ23_RS09970	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ23_RS09970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ23_RS09990	COG2255	four-way junction helicase activity
CTZ23_RS10000	COG0824	Thioesterase
CTZ23_RS10020	COG0823	Involved in the tonB-independent uptake of proteins
CTZ23_RS10040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ23_RS10070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTZ23_RS10075	COG0628	permease
CTZ23_RS10080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CTZ23_RS10085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ23_RS10105	COG0658	competence protein
CTZ23_RS10105	COG2333	competence protein COMEC
CTZ23_RS10110	COG1136	(ABC) transporter
CTZ23_RS10115	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ23_RS10130	COG1671	Belongs to the UPF0178 family
CTZ23_RS10170	COG1280	lysine exporter protein (LysE YggA)
CTZ23_RS10175	COG1522	sequence-specific DNA binding
CTZ23_RS10185	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ23_RS10200	COG0019	diaminopimelate decarboxylase activity
CTZ23_RS10210	COG1113	amino acid transport
CTZ23_RS10215	COG1115	amino acid carrier protein
CTZ23_RS10235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ23_RS10240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ23_RS10275	COG0583	DNA-binding transcription factor activity
CTZ23_RS10285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ23_RS10295	COG0174	glutamine synthetase
CTZ23_RS10300	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ23_RS10320	COG0302	gtp cyclohydrolase
CTZ23_RS10360	COG3739	integral membrane protein
CTZ23_RS10365	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CTZ23_RS10375	COG3385	transposase activity
CTZ23_RS10380	COG1741	Belongs to the pirin family
CTZ23_RS10385	COG3842	ATPase activity
CTZ23_RS10390	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ23_RS10420	COG0582	viral genome integration into host DNA
CTZ23_RS10450	COG2223	nitrite transmembrane transporter activity
CTZ23_RS10490	COG0798	PFAM Bile acid sodium symporter
CTZ23_RS10500	COG0640	Transcriptional regulator
CTZ23_RS10525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_RS10535	COG2184	nucleotidyltransferase activity
CTZ23_RS10580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ23_RS10585	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTZ23_RS10595	COG0037	tRNA processing
CTZ23_RS10600	COG1196	nuclear chromosome segregation
CTZ23_RS10600	COG0741	lytic transglycosylase activity
CTZ23_RS10600	COG0739	heme binding
CTZ23_RS10605	COG0501	Belongs to the peptidase M48B family
CTZ23_RS10615	COG2239	Acts as a magnesium transporter
CTZ23_RS10625	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ23_RS10650	COG1597	lipid kinase activity
CTZ23_RS10670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CTZ23_RS10705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ23_RS10720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ23_RS10725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CTZ23_RS10730	COG1534	Rna-binding protein
CTZ23_RS10745	COG0505	Belongs to the CarA family
CTZ23_RS10780	COG0110	maltose O-acetyltransferase activity
CTZ23_RS10785	COG0589	response to stress
CTZ23_RS10795	COG2321	neutral zinc metallopeptidase
CTZ23_RS10800	COG2354	Protein conserved in bacteria
CTZ23_RS10825	COG2268	Band 7 protein
CTZ23_RS10835	COG1215	transferase activity, transferring glycosyl groups
CTZ23_RS10840	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ23_RS10840	COG0726	polysaccharide deacetylase
CTZ23_RS10850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CTZ23_RS10860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ23_RS10875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ23_RS10880	COG1053	succinate dehydrogenase
CTZ23_RS10885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ23_RS10900	COG2072	flavoprotein involved in K transport
CTZ23_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS10915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CTZ23_RS10920	COG0714	Associated with various cellular activities
CTZ23_RS10930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ23_RS10930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ23_RS10960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_RS10970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CTZ23_RS10985	COG0564	pseudouridine synthase activity
CTZ23_RS10995	COG0358	DNA primase activity
CTZ23_RS11010	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ23_RS11040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ23_RS11080	COG0586	Pfam SNARE associated Golgi protein
CTZ23_RS11115	COG0321	lipoyl(octanoyl) transferase activity
CTZ23_RS11135	COG0531	amino acid
CTZ23_RS11140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ23_RS11145	COG1648	precorrin-2 dehydrogenase activity
CTZ23_RS11145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ23_RS11150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CTZ23_RS11160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ23_RS11185	COG0671	phosphoesterase, PA-phosphatase related
CTZ23_RS11190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS11200	COG1538	Outer membrane efflux protein
CTZ23_RS11205	COG0393	Putative heavy-metal-binding
CTZ23_RS11210	COG0393	Putative heavy-metal-binding
CTZ23_RS11225	COG0525	valine-tRNA ligase activity
CTZ23_RS11250	COG2323	membrane
CTZ23_RS11260	COG0765	amino acid transport
CTZ23_RS11265	COG0765	amino acid transport
CTZ23_RS11270	COG1126	abc transporter atp-binding protein
CTZ23_RS11275	COG3338	carbonate dehydratase activity
CTZ23_RS11295	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ23_RS11310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_RS11315	COG2205	protein histidine kinase activity
CTZ23_RS11320	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS11335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ23_RS11340	COG1652	LysM domain
CTZ23_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS11365	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ23_RS11370	COG3101	peptidyl-lysine hydroxylation
CTZ23_RS11375	COG0009	L-threonylcarbamoyladenylate synthase
CTZ23_RS11385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ23_RS11390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ23_RS11405	COG4106	trans-aconitate 2-methyltransferase activity
CTZ23_RS11420	COG2226	methyltransferase
CTZ23_RS11420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS11420	COG0596	Alpha beta hydrolase
CTZ23_RS11425	COG2193	ferroxidase activity
CTZ23_RS11430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTZ23_RS11435	COG3115	cell septum assembly
CTZ23_RS11440	COG1196	nuclear chromosome segregation
CTZ23_RS11450	COG0730	response to heat
CTZ23_RS11470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ23_RS11485	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CTZ23_RS11535	COG3328	transposase activity
CTZ23_RS11555	COG0628	permease
CTZ23_RS11565	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ23_RS11585	COG0564	pseudouridine synthase activity
CTZ23_RS11590	COG0346	lactoylglutathione lyase activity
CTZ23_RS11640	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ23_RS11670	COG0726	polysaccharide deacetylase
CTZ23_RS11670	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ23_RS11685	COG3328	transposase activity
CTZ23_RS11715	COG3177	Filamentation induced by cAMP protein fic
CTZ23_RS11740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ23_RS11745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTZ23_RS11770	COG0640	Transcriptional regulator
CTZ23_RS11785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ23_RS11800	COG0642	Histidine kinase
CTZ23_RS11880	COG0582	viral genome integration into host DNA
CTZ23_RS11890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ23_RS11895	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ23_RS11915	COG0420	3'-5' exonuclease activity
CTZ23_RS11945	COG0735	belongs to the Fur family
CTZ23_RS11950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_RS11955	COG2914	Belongs to the UPF0125 (RnfH) family
CTZ23_RS11970	COG0121	glutamine amidotransferase
CTZ23_RS11985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ23_RS12000	COG0210	DNA helicase
CTZ23_RS12005	COG2885	chlorophyll binding
CTZ23_RS12010	COG0204	Acyl-transferase
CTZ23_RS12020	COG0850	regulation of cytokinetic process
CTZ23_RS12025	COG2894	cell division
CTZ23_RS12040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ23_RS12040	COG1674	ftsk spoiiie
CTZ23_RS12045	COG0492	ferredoxin-NADP+ reductase activity
CTZ23_RS12050	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ23_RS12055	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CTZ23_RS12060	COG0456	acetyltransferase
CTZ23_RS12085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CTZ23_RS12100	COG1981	membrane
CTZ23_RS12105	COG1113	amino acid transport
CTZ23_RS12110	COG0251	oxidation-reduction process
CTZ23_RS12135	COG0352	thiamine-phosphate diphosphorylase activity
CTZ23_RS12135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ23_RS12135	COG0351	phosphomethylpyrimidine kinase
CTZ23_RS12150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ23_RS12170	COG2132	Multicopper oxidase
CTZ23_RS12180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ23_RS12195	COG4269	membrane
CTZ23_RS12215	COG1968	undecaprenyl-diphosphatase activity
CTZ23_RS12220	COG1214	PFAM Peptidase M22, glycoprotease
CTZ23_RS12230	COG0494	nUDIX hydrolase
CTZ23_RS12280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ23_RS12285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ23_RS12370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ23_RS12415	COG0037	tRNA processing
CTZ23_RS12425	COG0248	Ppx GppA phosphatase
CTZ23_RS12450	COG0072	phenylalanine-tRNA ligase activity
CTZ23_RS12485	COG1238	metal cluster binding
CTZ23_RS12490	COG0625	glutathione transferase activity
CTZ23_RS12515	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS12520	COG3028	Belongs to the UPF0307 family
CTZ23_RS12530	COG1660	Displays ATPase and GTPase activities
CTZ23_RS12545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ23_RS12550	COG0617	tRNA 3'-terminal CCA addition
CTZ23_RS12555	COG1555	photosystem II stabilization
CTZ23_RS12560	COG3956	TIGRFAM MazG family protein
CTZ23_RS12575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_RS12585	COG0124	histidyl-tRNA synthetase
CTZ23_RS12615	COG2975	iron-sulfur cluster assembly
CTZ23_RS12655	COG0440	acetolactate synthase activity
CTZ23_RS12660	COG0028	Belongs to the TPP enzyme family
CTZ23_RS12685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS12690	COG0577	efflux transmembrane transporter activity
CTZ23_RS12690	COG1136	(ABC) transporter
CTZ23_RS12695	COG1538	Outer membrane efflux protein
CTZ23_RS12730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ23_RS12735	COG1162	GTPase activity
CTZ23_RS12745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ23_RS12755	COG3385	transposase activity
CTZ23_RS12760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ23_RS12770	COG3781	membrane
CTZ23_RS12785	COG2350	Protein conserved in bacteria
CTZ23_RS12805	COG1666	GTP binding
CTZ23_RS12815	COG1607	acyl-coa hydrolase
CTZ23_RS12880	COG1183	phosphatidylcholine synthase activity
CTZ23_RS12885	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ23_RS12925	COG3385	transposase activity
CTZ23_RS12940	COG0739	heme binding
CTZ23_RS12940	COG0741	lytic transglycosylase activity
CTZ23_RS12940	COG1196	nuclear chromosome segregation
CTZ23_RS12950	COG1702	phosphate starvation-inducible protein PhoH
CTZ23_RS13000	COG1295	ribonuclease BN
CTZ23_RS13030	COG0788	formyltetrahydrofolate deformylase activity
CTZ23_RS13055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ23_RS13055	COG4651	solute:proton antiporter activity
CTZ23_RS13070	COG0724	RNA recognition motif
CTZ23_RS13075	COG0210	DNA helicase
CTZ23_RS13085	COG1929	Belongs to the glycerate kinase type-1 family
CTZ23_RS13115	COG2900	Belongs to the SlyX family
CTZ23_RS13120	COG0488	(ABC) transporter
CTZ23_RS13125	COG1560	Kdo2-lipid A biosynthetic process
CTZ23_RS13175	COG0473	3-isopropylmalate dehydrogenase activity
CTZ23_RS13190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CTZ23_RS13210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ23_RS13225	COG0494	nUDIX hydrolase
CTZ23_RS13245	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS13255	COG0753	catalase activity
CTZ23_RS13270	COG0583	DNA-binding transcription factor activity
CTZ23_RS13275	COG0546	phosphoglycolate phosphatase activity
CTZ23_RS13290	COG1530	ribonuclease E activity
CTZ23_RS13295	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS13320	COG1983	PspC domain protein
CTZ23_RS13325	COG0517	IMP dehydrogenase activity
CTZ23_RS13325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTZ23_RS13325	COG0617	tRNA 3'-terminal CCA addition
CTZ23_RS13335	COG0751	glycine-tRNA ligase activity
CTZ23_RS13365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTZ23_RS13380	COG2226	methyltransferase
CTZ23_RS13390	COG0493	'glutamate synthase
CTZ23_RS13390	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_RS13400	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ23_RS13410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ23_RS13425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ23_RS13435	COG0644	oxidoreductase
CTZ23_RS13435	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ23_RS13455	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ23_RS13460	COG4535	Mg2 and Co2 transporter CorC
CTZ23_RS13465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CTZ23_RS13485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ23_RS13495	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ23_RS13505	COG0789	Transcriptional regulator
CTZ23_RS13510	COG2841	Protein conserved in bacteria
CTZ23_RS13525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTZ23_RS13530	COG0675	Transposase, IS605 OrfB family
CTZ23_RS13535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ23_RS13540	COG1074	ATP-dependent DNA helicase activity
CTZ23_RS13545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ23_RS13575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ23_RS13585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ23_RS13600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ23_RS13600	COG2111	Na H antiporter
CTZ23_RS13605	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ23_RS13610	COG0651	ATP synthesis coupled electron transport
CTZ23_RS13615	COG1863	multisubunit Na H antiporter MnhE subunit
CTZ23_RS13620	COG2212	antiporter activity
CTZ23_RS13625	COG1320	monovalent cation:proton antiporter activity
CTZ23_RS13630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CTZ23_RS13640	COG0195	Participates in both transcription termination and antitermination
CTZ23_RS13645	COG0779	Required for maturation of 30S ribosomal subunits
CTZ23_RS13695	COG0237	dephospho-CoA kinase activity
CTZ23_RS13705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ23_RS13710	COG3123	guanosine phosphorylase activity
CTZ23_RS13715	COG0497	DNA recombination
CTZ23_RS13725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ23_RS13740	COG1132	(ABC) transporter
CTZ23_RS13745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ23_RS13775	COG1024	Enoyl-CoA hydratase
CTZ23_RS13775	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_RS13795	COG2233	PERMEase
CTZ23_RS13805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ23_RS13830	COG0326	Molecular chaperone. Has ATPase activity
CTZ23_RS13845	COG2056	Na+-H+ antiporter family
CTZ23_RS13865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CTZ23_RS13870	COG0085	RNA polymerase activity
CTZ23_RS13885	COG0081	regulation of translation
CTZ23_RS13940	COG0546	phosphoglycolate phosphatase activity
CTZ23_RS13970	COG0824	Thioesterase
CTZ23_RS13990	COG0181	hydroxymethylbilane synthase activity
CTZ23_RS14000	COG3275	phosphorelay sensor kinase activity
CTZ23_RS14035	COG0494	nUDIX hydrolase
CTZ23_RS14040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ23_RS14045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ23_RS14050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ23_RS14060	COG0772	Belongs to the SEDS family
CTZ23_RS14085	COG4974	Belongs to the 'phage' integrase family
CTZ23_RS14100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ23_RS14110	COG2197	response regulator
CTZ23_RS14125	COG0793	Belongs to the peptidase S41A family
CTZ23_RS14130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ23_RS14135	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ23_RS14140	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ23_RS14165	COG0586	Pfam SNARE associated Golgi protein
CTZ23_RS14180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ23_RS14180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ23_RS14190	COG0004	ammonium transporteR
CTZ23_RS14195	COG0347	Belongs to the P(II) protein family
CTZ23_RS14255	COG3293	Transposase
CTZ23_RS14280	COG3293	Transposase
CTZ23_RS14295	COG2826	transposase and inactivated derivatives, IS30 family
CTZ23_RS14300	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CTZ23_RS14310	COG2826	transposase and inactivated derivatives, IS30 family
CTZ23_RS14350	COG0606	chelatase, subunit chli
CTZ23_RS14365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ23_RS14380	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS14390	COG0477	Major facilitator Superfamily
CTZ23_RS14395	COG2860	membrane
CTZ23_RS14405	COG1253	flavin adenine dinucleotide binding
CTZ23_RS14425	COG2814	Major facilitator Superfamily
CTZ23_RS14440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ23_RS14465	COG2814	Major facilitator Superfamily
CTZ23_RS14515	COG0758	DNA mediated transformation
CTZ23_RS14530	COG0697	spore germination
CTZ23_RS14540	COG0386	Belongs to the glutathione peroxidase family
CTZ23_RS14575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CTZ23_RS14625	COG1121	(ABC) transporter
CTZ23_RS14630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ23_RS14640	COG2837	iron assimilation
CTZ23_RS14665	COG0281	malic enzyme
CTZ23_RS14710	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ23_RS14710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ23_RS14715	COG2259	Doxx family
CTZ23_RS14720	COG0586	Pfam SNARE associated Golgi protein
CTZ23_RS14735	COG1192	Involved in chromosome partitioning
CTZ23_RS14745	COG0271	Belongs to the BolA IbaG family
CTZ23_RS14770	COG3550	peptidyl-serine autophosphorylation
CTZ23_RS14775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTZ23_RS14800	COG4628	conserved protein (DUF2132)
CTZ23_RS14810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CTZ23_RS14825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ23_RS14835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ23_RS14855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ23_RS14865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTZ23_RS14875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ23_RS14885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTZ23_RS14895	COG1086	Polysaccharide biosynthesis protein
CTZ23_RS14910	COG0110	maltose O-acetyltransferase activity
CTZ23_RS14935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ23_RS14990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS14995	COG1309	transcriptional regulator
CTZ23_RS15005	COG2233	PERMEase
CTZ23_RS15020	COG0129	dihydroxy-acid dehydratase activity
CTZ23_RS15035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTZ23_RS15045	COG0733	neurotransmitter:sodium symporter activity
CTZ23_RS15050	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_RS15060	COG3385	transposase activity
CTZ23_RS15065	COG2814	Major facilitator Superfamily
CTZ23_RS15095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ23_RS15105	COG0657	acetylesterase activity
CTZ23_RS15140	COG2951	lytic endotransglycosylase activity
CTZ23_RS15150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ23_RS15170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ23_RS15185	COG2388	GCN5-related N-acetyl-transferase
CTZ23_RS15195	COG0861	Integral membrane protein TerC family
CTZ23_RS15200	COG0402	S-adenosylhomocysteine deaminase activity
CTZ23_RS15210	COG0675	Transposase, IS605 OrfB family
CTZ23_RS15220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ23_RS15225	COG1230	cation diffusion facilitator family transporter
CTZ23_RS15250	COG0706	membrane insertase activity
CTZ23_RS15255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CTZ23_RS15260	COG0594	ribonuclease P activity