locus-tag	class	description
CTZ23_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTZ23_RS00010	COG0592	DNA-directed DNA polymerase activity
CTZ23_RS00020	COG0187	DNA topoisomerase II activity
CTZ23_RS00025	COG1063	alcohol dehydrogenase
CTZ23_RS00030	COG3328	transposase activity
CTZ23_RS00035	COG0488	(ABC) transporter
CTZ23_RS00060	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ23_RS00065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ23_RS00075	COG0737	Belongs to the 5'-nucleotidase family
CTZ23_RS00105	COG2814	Major facilitator Superfamily
CTZ23_RS00110	COG2133	pyrroloquinoline quinone binding
CTZ23_RS00120	COG1047	Peptidyl-prolyl cis-trans
CTZ23_RS00125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CTZ23_RS00130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ23_RS00135	COG0196	riboflavin kinase activity
CTZ23_RS00145	COG1309	transcriptional regulator
CTZ23_RS00150	COG1116	anion transmembrane transporter activity
CTZ23_RS00155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ23_RS00160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ23_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_RS00170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_RS00175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CTZ23_RS00175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTZ23_RS00195	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS00200	COG0546	phosphoglycolate phosphatase activity
CTZ23_RS00205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ23_RS00215	COG1309	transcriptional regulator
CTZ23_RS00220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CTZ23_RS00230	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ23_RS00250	COG1064	alcohol dehydrogenase
CTZ23_RS00255	COG2818	Glycosylase
CTZ23_RS00265	COG0739	heme binding
CTZ23_RS00270	COG1194	a g-specific adenine glycosylase
CTZ23_RS00285	COG5487	UPF0391 membrane protein
CTZ23_RS00290	COG2983	Belongs to the UPF0260 family
CTZ23_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ23_RS00300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CTZ23_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ23_RS00320	COG1335	isochorismatase
CTZ23_RS00325	COG0385	Bile acid
CTZ23_RS00340	COG3830	Belongs to the UPF0237 family
CTZ23_RS00340	COG0560	Phosphoserine phosphatase
CTZ23_RS00360	COG0753	catalase activity
CTZ23_RS00405	COG0534	Mate efflux family protein
CTZ23_RS00410	COG0436	Aminotransferase
CTZ23_RS00415	COG2733	membrane
CTZ23_RS00430	COG2918	glutathione biosynthetic process
CTZ23_RS00435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CTZ23_RS00445	COG3150	esterase
CTZ23_RS00485	COG0471	metal ion transport
CTZ23_RS00495	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ23_RS00500	COG4266	Belongs to the allantoicase family
CTZ23_RS00505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_RS00510	COG1247	-acetyltransferase
CTZ23_RS00550	COG0625	glutathione transferase activity
CTZ23_RS00555	COG3706	GGDEF domain
CTZ23_RS00560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ23_RS00575	COG1393	Belongs to the ArsC family
CTZ23_RS00580	COG0708	Exodeoxyribonuclease III
CTZ23_RS00605	COG0189	ligase activity
CTZ23_RS00610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTZ23_RS00615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ23_RS00625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ23_RS00635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ23_RS00665	COG2119	membrane
CTZ23_RS00670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_RS00670	COG0426	domain, Protein
CTZ23_RS00695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ23_RS00720	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS00725	COG1519	Transferase
CTZ23_RS00730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ23_RS00735	COG0668	transmembrane transport
CTZ23_RS00740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ23_RS00755	COG0431	NADPH-dependent FMN reductase
CTZ23_RS00770	COG2205	protein histidine kinase activity
CTZ23_RS00770	COG0784	Response regulator, receiver
CTZ23_RS00775	COG3162	membrane
CTZ23_RS00780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_RS00800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ23_RS00825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ23_RS00830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ23_RS00850	COG2814	Major facilitator Superfamily
CTZ23_RS00855	COG0629	single-stranded DNA binding
CTZ23_RS00895	COG2801	Transposase and inactivated derivatives
CTZ23_RS00915	COG2801	Transposase and inactivated derivatives
CTZ23_RS00955	COG2205	protein histidine kinase activity
CTZ23_RS00960	COG3174	membrane
CTZ23_RS00965	COG2217	Heavy metal translocating P-type atpase
CTZ23_RS01075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ23_RS01135	COG2132	Multicopper oxidase
CTZ23_RS01150	COG3077	Addiction module antitoxin, RelB DinJ family
CTZ23_RS01195	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CTZ23_RS01220	COG3158	transport of potassium into the cell
CTZ23_RS01260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ23_RS01275	COG0697	spore germination
CTZ23_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ23_RS01325	COG0427	acetyl-CoA hydrolase
CTZ23_RS01355	COG4221	oxidoreductase activity
CTZ23_RS01375	COG0488	(ABC) transporter
CTZ23_RS01395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ23_RS01405	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ23_RS01410	COG0275	rRNA processing
CTZ23_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ23_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ23_RS01440	COG2226	methyltransferase
CTZ23_RS01445	COG3385	transposase activity
CTZ23_RS01495	COG0069	glutamate synthase activity
CTZ23_RS01495	COG0067	glutamate synthase
CTZ23_RS01495	COG0070	glutamate synthase
CTZ23_RS01500	COG0493	'glutamate synthase
CTZ23_RS01510	COG1704	LemA family
CTZ23_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ23_RS01525	COG4969	Belongs to the N-Me-Phe pilin family
CTZ23_RS01530	COG3307	-O-antigen
CTZ23_RS01540	COG3307	-O-antigen
CTZ23_RS01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_RS01565	COG1758	RNA polymerase activity
CTZ23_RS01570	COG0194	GDP metabolic process
CTZ23_RS01615	COG0228	four-way junction DNA binding
CTZ23_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ23_RS01630	COG0335	large ribosomal subunit rRNA binding
CTZ23_RS01635	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ23_RS01640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ23_RS01645	COG5380	lipid catabolic process
CTZ23_RS01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ23_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ23_RS01680	COG0277	FAD linked oxidase domain protein
CTZ23_RS01695	COG2814	Major facilitator Superfamily
CTZ23_RS01705	COG0628	permease
CTZ23_RS01710	COG1192	Involved in chromosome partitioning
CTZ23_RS01725	COG2226	methyltransferase
CTZ23_RS01745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CTZ23_RS01750	COG0254	rRNA binding
CTZ23_RS01755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ23_RS01760	COG0534	Mate efflux family protein
CTZ23_RS01770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ23_RS01775	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS01790	COG0408	coproporphyrinogen oxidase activity
CTZ23_RS01795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ23_RS01820	COG1127	ABC transporter
CTZ23_RS01825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ23_RS01830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTZ23_RS01835	COG2854	intermembrane phospholipid transfer
CTZ23_RS01845	COG0598	Magnesium transport protein CorA
CTZ23_RS01860	COG1040	competence protein
CTZ23_RS01865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ23_RS01875	COG2937	Belongs to the GPAT DAPAT family
CTZ23_RS01880	COG1946	Acyl-CoA thioesterase
CTZ23_RS01885	COG1301	dicarboxylic acid transport
CTZ23_RS01905	COG1959	2 iron, 2 sulfur cluster binding
CTZ23_RS01915	COG0433	COG0433 Predicted ATPase
CTZ23_RS01940	COG0088	Forms part of the polypeptide exit tunnel
CTZ23_RS01970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CTZ23_RS02005	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CTZ23_RS02010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CTZ23_RS02020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CTZ23_RS02055	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CTZ23_RS02060	COG0202	RNA polymerase activity
CTZ23_RS02070	COG2072	flavoprotein involved in K transport
CTZ23_RS02075	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS02080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ23_RS02115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ23_RS02120	COG0339	signal peptide processing
CTZ23_RS02130	COG0557	exoribonuclease II activity
CTZ23_RS02165	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ23_RS02215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CTZ23_RS02225	COG3040	lipid binding
CTZ23_RS02285	COG2813	Specifically methylates the guanine in position
CTZ23_RS02285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS02290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS02295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ23_RS02305	COG3128	pkhd-type hydroxylase
CTZ23_RS02310	COG4774	siderophore transport
CTZ23_RS02315	COG4771	TonB-dependent receptor
CTZ23_RS02325	COG0740	serine-type endopeptidase activity
CTZ23_RS02340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ23_RS02340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ23_RS02350	COG0857	belongs to the CobB CobQ family
CTZ23_RS02350	COG0280	phosphate acetyltransferase
CTZ23_RS02355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ23_RS02385	COG0793	Belongs to the peptidase S41A family
CTZ23_RS02415	COG3046	protein related to deoxyribodipyrimidine photolyase
CTZ23_RS02445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ23_RS02460	COG0642	Histidine kinase
CTZ23_RS02465	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS02495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ23_RS02520	COG4221	oxidoreductase activity
CTZ23_RS02525	COG0583	DNA-binding transcription factor activity
CTZ23_RS02530	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ23_RS02535	COG0604	alcohol dehydrogenase
CTZ23_RS02535	COG3321	synthase
CTZ23_RS02550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CTZ23_RS02560	COG1979	alcohol dehydrogenase
CTZ23_RS02570	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS02580	COG1309	transcriptional regulator
CTZ23_RS02585	COG2130	NADP-dependent
CTZ23_RS02655	COG2801	Transposase and inactivated derivatives
CTZ23_RS02660	COG2862	Uncharacterized protein family, UPF0114
CTZ23_RS02690	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ23_RS02705	COG0084	hydrolase, TatD family'
CTZ23_RS02710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ23_RS02715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ23_RS02780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_RS02850	COG2814	Major facilitator Superfamily
CTZ23_RS02855	COG0697	spore germination
CTZ23_RS02880	COG3622	Belongs to the hyi family
CTZ23_RS02890	COG1024	Enoyl-CoA hydratase
CTZ23_RS02895	COG5002	protein histidine kinase activity
CTZ23_RS02895	COG2205	protein histidine kinase activity
CTZ23_RS02895	COG0784	Response regulator, receiver
CTZ23_RS02905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ23_RS02920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_RS02940	COG1862	Preprotein translocase
CTZ23_RS02955	COG2203	Gaf domain
CTZ23_RS02955	COG3706	GGDEF domain
CTZ23_RS02955	COG5001	Diguanylate cyclase
CTZ23_RS02955	COG4251	negative regulation of phosphorylation
CTZ23_RS02960	COG1704	LemA family
CTZ23_RS02970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CTZ23_RS02990	COG5002	protein histidine kinase activity
CTZ23_RS02995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ23_RS03015	COG0463	Glycosyl transferase, family 2
CTZ23_RS03050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CTZ23_RS03090	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS03095	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS03110	COG2205	protein histidine kinase activity
CTZ23_RS03115	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS03125	COG2315	Protein conserved in bacteria
CTZ23_RS03130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ23_RS03150	COG2096	Adenosyltransferase
CTZ23_RS03155	COG4206	TonB-dependent receptor
CTZ23_RS03200	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CTZ23_RS03205	COG0285	dihydrofolate synthase activity
CTZ23_RS03220	COG0450	alkyl hydroperoxide reductase
CTZ23_RS03240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ23_RS03245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ23_RS03270	COG2885	chlorophyll binding
CTZ23_RS03330	COG2969	positive regulation of protein catabolic process
CTZ23_RS03335	COG0625	glutathione transferase activity
CTZ23_RS03340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ23_RS03350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTZ23_RS03355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ23_RS03360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ23_RS03390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ23_RS03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ23_RS03405	COG1408	metallophosphoesterase
CTZ23_RS03415	COG0477	Major facilitator Superfamily
CTZ23_RS03420	COG1272	protein, Hemolysin III
CTZ23_RS03445	COG1024	Enoyl-CoA hydratase
CTZ23_RS03445	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_RS03450	COG0183	Belongs to the thiolase family
CTZ23_RS03455	COG2207	Transcriptional regulator
CTZ23_RS03460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ23_RS03465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS03480	COG0183	Belongs to the thiolase family
CTZ23_RS03500	COG0833	amino acid
CTZ23_RS03510	COG2233	PERMEase
CTZ23_RS03515	COG1217	gtp-binding protein TYPA
CTZ23_RS03520	COG1970	mechanosensitive ion channel activity
CTZ23_RS03525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_RS03535	COG1877	trehalose-phosphatase activity
CTZ23_RS03540	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ23_RS03550	COG0363	glucosamine-6-phosphate deaminase activity
CTZ23_RS03580	COG0354	folic acid binding
CTZ23_RS03600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ23_RS03605	COG0154	amidase activity
CTZ23_RS03610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ23_RS03615	COG1077	Cell shape determining protein MreB Mrl
CTZ23_RS03620	COG1792	Involved in formation and maintenance of cell shape
CTZ23_RS03625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ23_RS03630	COG0424	maF-like protein
CTZ23_RS03635	COG1530	ribonuclease E activity
CTZ23_RS03640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ23_RS03680	COG0625	glutathione transferase activity
CTZ23_RS03700	COG1113	amino acid transport
CTZ23_RS03705	COG2828	Protein conserved in bacteria
CTZ23_RS03710	COG0142	geranyltranstransferase activity
CTZ23_RS03720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_RS03740	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ23_RS03750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CTZ23_RS03755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_RS03760	COG0839	Belongs to the complex I subunit 6 family
CTZ23_RS03765	COG0713	ATP synthesis coupled electron transport
CTZ23_RS03770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ23_RS03775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_RS03790	COG1278	Cold shock
CTZ23_RS03795	COG0583	DNA-binding transcription factor activity
CTZ23_RS03800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_RS03820	COG0668	transmembrane transport
CTZ23_RS03830	COG2081	HI0933 family
CTZ23_RS03850	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ23_RS03865	COG0004	ammonium transporteR
CTZ23_RS03890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ23_RS03890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ23_RS03895	COG0489	protein tyrosine kinase activity
CTZ23_RS03910	COG2358	TRAP transporter, solute receptor (TAXI family
CTZ23_RS03945	COG0442	prolyl-tRNA aminoacylation
CTZ23_RS03980	COG0840	transmembrane signaling receptor activity
CTZ23_RS03985	COG0643	Histidine kinase
CTZ23_RS03985	COG2198	Histidine kinase
CTZ23_RS03985	COG0784	Response regulator, receiver
CTZ23_RS04000	COG5510	response to toxic substance
CTZ23_RS04010	COG2832	Protein of unknown function (DUF454)
CTZ23_RS04015	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ23_RS04070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTZ23_RS04080	COG1289	transmembrane transporter activity
CTZ23_RS04085	COG2814	Major facilitator Superfamily
CTZ23_RS04100	COG0786	glutamate:sodium symporter activity
CTZ23_RS04105	COG1115	amino acid carrier protein
CTZ23_RS04110	COG2059	Chromate
CTZ23_RS04115	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ23_RS04125	COG1607	acyl-coa hydrolase
CTZ23_RS04160	COG0523	cobalamin synthesis protein
CTZ23_RS04165	COG4681	YaeQ
CTZ23_RS04175	COG2203	Gaf domain
CTZ23_RS04175	COG2199	diguanylate cyclase activity
CTZ23_RS04205	COG0477	Major facilitator Superfamily
CTZ23_RS04210	COG3706	GGDEF domain
CTZ23_RS04215	COG2066	Belongs to the glutaminase family
CTZ23_RS04220	COG2376	Dihydroxyacetone kinase
CTZ23_RS04240	COG0306	phosphate transporter
CTZ23_RS04265	COG4771	TonB-dependent receptor
CTZ23_RS04290	COG4181	ATPase activity
CTZ23_RS04295	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ23_RS04305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ23_RS04315	COG0583	DNA-binding transcription factor activity
CTZ23_RS04325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS04330	COG1773	rubredoxin
CTZ23_RS04335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTZ23_RS04365	COG3118	belongs to the thioredoxin family
CTZ23_RS04385	COG1253	flavin adenine dinucleotide binding
CTZ23_RS04405	COG3015	lipoprotein NlpE involved in copper resistance
CTZ23_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS04425	COG0829	nickel cation binding
CTZ23_RS04445	COG0804	urea catabolic process
CTZ23_RS04460	COG0830	nickel cation binding
CTZ23_RS04475	COG0742	ribosomal rna small subunit methyltransferase
CTZ23_RS04480	COG0768	penicillin binding
CTZ23_RS04505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ23_RS04510	COG2878	Part of a membrane complex involved in electron transport
CTZ23_RS04515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ23_RS04525	COG3384	dioxygenase
CTZ23_RS04535	COG2234	aminopeptidase activity
CTZ23_RS04545	COG0675	Transposase, IS605 OrfB family
CTZ23_RS04550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ23_RS04570	COG2186	Transcriptional regulator
CTZ23_RS04580	COG0277	FAD linked oxidase domain protein
CTZ23_RS04615	COG3079	Belongs to the UPF0149 family
CTZ23_RS04620	COG0006	proline dipeptidase activity
CTZ23_RS04630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_RS04635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_RS04670	COG2816	NAD+ diphosphatase activity
CTZ23_RS04685	COG0741	lytic transglycosylase activity
CTZ23_RS04685	COG1388	LysM domain
CTZ23_RS04690	COG4166	transmembrane transport
CTZ23_RS04695	COG4174	ABC transporter (Permease)
CTZ23_RS04700	COG4239	(ABC) transporter, permease
CTZ23_RS04705	COG4172	Belongs to the ABC transporter superfamily
CTZ23_RS04730	COG0833	amino acid
CTZ23_RS04750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ23_RS04755	COG0418	dihydroorotase activity
CTZ23_RS04760	COG2203	Gaf domain
CTZ23_RS04760	COG3706	GGDEF domain
CTZ23_RS04760	COG4251	negative regulation of phosphorylation
CTZ23_RS04760	COG5001	Diguanylate cyclase
CTZ23_RS04775	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS04775	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ23_RS04790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ23_RS04840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ23_RS04845	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ23_RS04865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ23_RS04870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ23_RS04875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ23_RS04910	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS04920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ23_RS04930	COG2175	clavaminate synthase activity
CTZ23_RS04950	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ23_RS04975	COG2951	lytic endotransglycosylase activity
CTZ23_RS04990	COG0842	Transport permease protein
CTZ23_RS04995	COG1131	(ABC) transporter
CTZ23_RS05055	COG3385	transposase activity
CTZ23_RS05060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ23_RS05080	COG3634	alkyl hydroperoxide reductase activity
CTZ23_RS05085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_RS05090	COG0826	peptidase U32
CTZ23_RS05100	COG0640	Transcriptional regulator
CTZ23_RS05110	COG0798	PFAM Bile acid sodium symporter
CTZ23_RS05115	COG0431	NADPH-dependent FMN reductase
CTZ23_RS05120	COG0789	Transcriptional regulator
CTZ23_RS05135	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ23_RS05145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTZ23_RS05180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ23_RS05185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ23_RS05190	COG3139	Protein of unknown function (DUF1315)
CTZ23_RS05200	COG1301	dicarboxylic acid transport
CTZ23_RS05205	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS05210	COG0693	protein deglycase activity
CTZ23_RS05220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTZ23_RS05225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ23_RS05245	COG0415	Belongs to the DNA photolyase family
CTZ23_RS05250	COG1047	Peptidyl-prolyl cis-trans
CTZ23_RS05255	COG1252	NADH dehydrogenase
CTZ23_RS05260	COG1686	Belongs to the peptidase S11 family
CTZ23_RS05275	COG1187	pseudouridine synthase activity
CTZ23_RS05285	COG0739	heme binding
CTZ23_RS05300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_RS05310	COG0612	Peptidase, M16
CTZ23_RS05320	COG3385	transposase activity
CTZ23_RS05350	COG0352	thiamine-phosphate diphosphorylase activity
CTZ23_RS05365	COG3328	transposase activity
CTZ23_RS05435	COG0596	Alpha beta hydrolase
CTZ23_RS05440	COG1309	transcriptional regulator
CTZ23_RS05505	COG1278	Cold shock
CTZ23_RS05520	COG2070	2-Nitropropane dioxygenase
CTZ23_RS05545	COG2391	methyltransferase activity
CTZ23_RS05555	COG3634	alkyl hydroperoxide reductase activity
CTZ23_RS05585	COG1643	Atp-dependent helicase
CTZ23_RS05610	COG0517	IMP dehydrogenase activity
CTZ23_RS05610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ23_RS05615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ23_RS05625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ23_RS05630	COG1137	ATPase activity
CTZ23_RS05665	COG4122	O-methyltransferase activity
CTZ23_RS05675	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ23_RS05715	COG2011	ABC-type metal ion transport system permease component
CTZ23_RS05720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ23_RS05750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ23_RS05790	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ23_RS05800	COG1305	Transglutaminase-like
CTZ23_RS05815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ23_RS05830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTZ23_RS05835	COG0360	Binds together with S18 to 16S ribosomal RNA
CTZ23_RS05845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ23_RS05850	COG1845	cytochrome c oxidase, subunit III
CTZ23_RS05855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ23_RS05860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ23_RS05885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ23_RS05905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CTZ23_RS05915	COG3781	membrane
CTZ23_RS05935	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS05940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ23_RS05950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTZ23_RS05960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTZ23_RS05975	COG0477	Major facilitator Superfamily
CTZ23_RS06045	COG0308	aminopeptidase N
CTZ23_RS06055	COG0589	response to stress
CTZ23_RS06060	COG0589	response to stress
CTZ23_RS06070	COG3135	benzoate transporter
CTZ23_RS06080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTZ23_RS06095	COG0183	Belongs to the thiolase family
CTZ23_RS06105	COG2030	dehydratase
CTZ23_RS06110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ23_RS06125	COG0824	Thioesterase
CTZ23_RS06130	COG1454	alcohol dehydrogenase
CTZ23_RS06135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ23_RS06155	COG0069	glutamate synthase activity
CTZ23_RS06165	COG4585	Histidine kinase
CTZ23_RS06170	COG2850	peptidyl-arginine hydroxylation
CTZ23_RS06175	COG0424	maF-like protein
CTZ23_RS06200	COG0697	spore germination
CTZ23_RS06240	COG3698	Phosphodiester glycosidase
CTZ23_RS06260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ23_RS06260	COG0506	proline dehydrogenase activity
CTZ23_RS06260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ23_RS06270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_RS06275	COG1027	Aspartate ammonia-lyase
CTZ23_RS06280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ23_RS06285	COG0583	DNA-binding transcription factor activity
CTZ23_RS06290	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS06295	COG2814	Major facilitator Superfamily
CTZ23_RS06300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ23_RS06315	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_RS06315	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ23_RS06350	COG0148	phosphopyruvate hydratase activity
CTZ23_RS06365	COG0772	Belongs to the SEDS family
CTZ23_RS06380	COG2137	regulation of response to DNA damage stimulus
CTZ23_RS06390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ23_RS06395	COG1011	Hydrolase
CTZ23_RS06410	COG0268	Binds directly to 16S ribosomal RNA
CTZ23_RS06415	COG0702	epimerase
CTZ23_RS06420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ23_RS06435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ23_RS06465	COG0316	Belongs to the HesB IscA family
CTZ23_RS06470	COG0822	iron-sulfur transferase activity
CTZ23_RS06500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_RS06555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ23_RS06575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ23_RS06590	COG0617	tRNA 3'-terminal CCA addition
CTZ23_RS06590	COG0517	IMP dehydrogenase activity
CTZ23_RS06590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTZ23_RS06620	COG0612	Peptidase, M16
CTZ23_RS06625	COG0552	protein localization to endoplasmic reticulum
CTZ23_RS06670	COG0693	protein deglycase activity
CTZ23_RS06680	COG1283	sodium-dependent phosphate transmembrane transporter activity
CTZ23_RS06690	COG1346	cytolysis
CTZ23_RS06700	COG0583	DNA-binding transcription factor activity
CTZ23_RS06720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTZ23_RS06730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ23_RS06735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ23_RS06740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ23_RS06760	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS06765	COG2207	Transcriptional regulator
CTZ23_RS06770	COG2814	Major facilitator Superfamily
CTZ23_RS06780	COG1271	oxidase subunit
CTZ23_RS06785	COG1294	oxidase, subunit
CTZ23_RS06795	COG1525	nuclease
CTZ23_RS06845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ23_RS06850	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ23_RS06870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ23_RS06880	COG2814	Major facilitator Superfamily
CTZ23_RS06900	COG1132	(ABC) transporter
CTZ23_RS06910	COG0668	transmembrane transport
CTZ23_RS06915	COG3122	Protein conserved in bacteria
CTZ23_RS06935	COG0640	Transcriptional regulator
CTZ23_RS06945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ23_RS06950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_RS06950	COG1116	anion transmembrane transporter activity
CTZ23_RS06960	COG2223	nitrite transmembrane transporter activity
CTZ23_RS06965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS06970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_RS06975	COG0243	molybdopterin cofactor binding
CTZ23_RS06985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ23_RS07000	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ23_RS07000	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ23_RS07005	COG0303	'Molybdopterin
CTZ23_RS07015	COG4149	molybdate abc transporter
CTZ23_RS07020	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ23_RS07025	COG0583	DNA-binding transcription factor activity
CTZ23_RS07045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS07050	COG0183	Belongs to the thiolase family
CTZ23_RS07055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ23_RS07060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ23_RS07065	COG3135	benzoate transporter
CTZ23_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS07075	COG0543	2 iron, 2 sulfur cluster binding
CTZ23_RS07075	COG0633	Ferredoxin
CTZ23_RS07080	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ23_RS07085	COG4638	Rieske (2fe-2S)
CTZ23_RS07095	COG4829	muconolactone delta-isomerase
CTZ23_RS07100	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ23_RS07105	COG0583	DNA-binding transcription factor activity
CTZ23_RS07110	COG2814	Major facilitator Superfamily
CTZ23_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS07150	COG2223	nitrite transmembrane transporter activity
CTZ23_RS07160	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CTZ23_RS07165	COG2116	formate transmembrane transporter activity
CTZ23_RS07170	COG0515	serine threonine protein kinase
CTZ23_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS07230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ23_RS07235	COG1309	transcriptional regulator
CTZ23_RS07240	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_RS07255	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS07265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ23_RS07285	COG2026	Addiction module toxin, RelE StbE family
CTZ23_RS07300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTZ23_RS07305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_RS07310	COG0730	response to heat
CTZ23_RS07355	COG2801	Transposase and inactivated derivatives
CTZ23_RS07450	COG0596	Alpha beta hydrolase
CTZ23_RS07485	COG0511	ligase activity, forming carbon-carbon bonds
CTZ23_RS07490	COG0439	Biotin carboxylase
CTZ23_RS07505	COG2814	Major facilitator Superfamily
CTZ23_RS07510	COG3038	cytochrome b561
CTZ23_RS07540	COG1546	Belongs to the CinA family
CTZ23_RS07540	COG1058	Belongs to the CinA family
CTZ23_RS07550	COG0372	Belongs to the citrate synthase family
CTZ23_RS07585	COG0542	response to heat
CTZ23_RS07590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ23_RS07615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CTZ23_RS07625	COG0569	domain protein
CTZ23_RS07630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ23_RS07650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ23_RS07660	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ23_RS07675	COG1294	oxidase, subunit
CTZ23_RS07680	COG4890	Cyd operon protein YbgT
CTZ23_RS07715	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS07720	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS07740	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ23_RS07745	COG2207	Transcriptional regulator
CTZ23_RS07750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_RS07755	COG0730	response to heat
CTZ23_RS07760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ23_RS07790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_RS07800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_RS07810	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_RS07825	COG0575	Belongs to the CDS family
CTZ23_RS07830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ23_RS07835	COG0233	cytoplasmic translational termination
CTZ23_RS07850	COG3852	Histidine kinase
CTZ23_RS07855	COG2204	response regulator
CTZ23_RS07865	COG0583	DNA-binding transcription factor activity
CTZ23_RS07895	COG1253	flavin adenine dinucleotide binding
CTZ23_RS07915	COG3385	transposase activity
CTZ23_RS07920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ23_RS07925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ23_RS07940	COG2431	L-lysine efflux transmembrane transporter activity
CTZ23_RS07955	COG0776	regulation of translation
CTZ23_RS07985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTZ23_RS08020	COG0084	hydrolase, TatD family'
CTZ23_RS08040	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ23_RS08045	COG1132	(ABC) transporter
CTZ23_RS08055	COG0811	peptide transport
CTZ23_RS08060	COG1475	DNA binding
CTZ23_RS08065	COG1192	Involved in chromosome partitioning
CTZ23_RS08075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ23_RS08080	COG3178	'Phosphotransferase
CTZ23_RS08090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_RS08095	COG1923	regulation of RNA biosynthetic process
CTZ23_RS08105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ23_RS08110	COG0802	atpase or kinase
CTZ23_RS08135	COG2707	UPF0756 membrane protein
CTZ23_RS08145	COG0583	DNA-binding transcription factor activity
CTZ23_RS08150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ23_RS08160	COG1454	alcohol dehydrogenase
CTZ23_RS08180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ23_RS08180	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ23_RS08185	COG2353	YceI-like domain
CTZ23_RS08195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ23_RS08200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CTZ23_RS08240	COG1254	Belongs to the acylphosphatase family
CTZ23_RS08245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ23_RS08245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ23_RS08250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTZ23_RS08270	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS08280	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ23_RS08285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ23_RS08290	COG0183	Belongs to the thiolase family
CTZ23_RS08295	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_RS08300	COG1024	Enoyl-CoA hydratase
CTZ23_RS08305	COG1024	Enoyl-CoA hydratase
CTZ23_RS08310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_RS08315	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ23_RS08320	COG3396	Phenylacetate-CoA oxygenase
CTZ23_RS08325	COG3460	Phenylacetate-CoA oxygenase
CTZ23_RS08330	COG3396	Phenylacetate-CoA oxygenase
CTZ23_RS08335	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_RS08335	COG2030	dehydratase
CTZ23_RS08360	COG0783	Belongs to the Dps family
CTZ23_RS08445	COG5002	protein histidine kinase activity
CTZ23_RS08445	COG5001	Diguanylate cyclase
CTZ23_RS08455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CTZ23_RS08475	COG4773	Receptor
CTZ23_RS08515	COG3328	transposase activity
CTZ23_RS08525	COG1401	restriction endodeoxyribonuclease activity
CTZ23_RS08535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_RS08560	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_RS08565	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CTZ23_RS08610	COG2801	Transposase and inactivated derivatives
CTZ23_RS08640	COG0582	viral genome integration into host DNA
CTZ23_RS08645	COG0582	viral genome integration into host DNA
CTZ23_RS08655	COG3772	lysozyme
CTZ23_RS08735	COG3561	AntA/AntB antirepressor
CTZ23_RS08785	COG2369	cell adhesion
CTZ23_RS08790	COG3567	Phage-associated protein, HI1409 family
CTZ23_RS08795	COG5410	chromosome segregation
CTZ23_RS08815	COG2801	Transposase and inactivated derivatives
CTZ23_RS08905	COG5377	YqaJ viral recombinase family
CTZ23_RS08945	COG0204	Acyl-transferase
CTZ23_RS08970	COG0012	GTP binding
CTZ23_RS08980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ23_RS08995	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CTZ23_RS09005	COG0386	Belongs to the glutathione peroxidase family
CTZ23_RS09010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTZ23_RS09015	COG0436	Aminotransferase
CTZ23_RS09020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTZ23_RS09020	COG2755	lipolytic protein G-D-S-L family
CTZ23_RS09060	COG0515	serine threonine protein kinase
CTZ23_RS09060	COG2815	serine threonine protein kinase
CTZ23_RS09095	COG1610	YqeY-like protein
CTZ23_RS09110	COG4783	chaperone-mediated protein folding
CTZ23_RS09175	COG0513	Belongs to the DEAD box helicase family
CTZ23_RS09195	COG2363	Small membrane protein
CTZ23_RS09215	COG0659	secondary active sulfate transmembrane transporter activity
CTZ23_RS09225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ23_RS09245	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS09250	COG1309	transcriptional regulator
CTZ23_RS09255	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS09260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ23_RS09265	COG1024	Enoyl-CoA hydratase
CTZ23_RS09270	COG4770	biotin carboxylase activity
CTZ23_RS09285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ23_RS09300	COG0540	Belongs to the ATCase OTCase family
CTZ23_RS09320	COG1765	OsmC-like protein
CTZ23_RS09330	COG0667	Aldo Keto reductase
CTZ23_RS09345	COG0501	Belongs to the peptidase M48B family
CTZ23_RS09350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ23_RS09365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ23_RS09375	COG0527	aspartate kinase activity
CTZ23_RS09385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ23_RS09395	COG1215	transferase activity, transferring glycosyl groups
CTZ23_RS09405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ23_RS09410	COG2252	PERMEase
CTZ23_RS09445	COG0714	Associated with various cellular activities
CTZ23_RS09450	COG2879	small protein
CTZ23_RS09460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CTZ23_RS09465	COG1509	lysine 2,3-aminomutase activity
CTZ23_RS09500	COG1067	ATP-dependent peptidase activity
CTZ23_RS09505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ23_RS09510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ23_RS09515	COG0583	DNA-binding transcription factor activity
CTZ23_RS09525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ23_RS09540	COG1686	Belongs to the peptidase S11 family
CTZ23_RS09545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ23_RS09550	COG3328	transposase activity
CTZ23_RS09555	COG1280	lysine exporter protein (LysE YggA)
CTZ23_RS09585	COG0616	signal peptide processing
CTZ23_RS09595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ23_RS09605	COG0573	inorganic phosphate transmembrane transporter activity
CTZ23_RS09615	COG0076	glutamate decarboxylase activity
CTZ23_RS09620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ23_RS09630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CTZ23_RS09650	COG1733	regulation of RNA biosynthetic process
CTZ23_RS09655	COG0702	epimerase
CTZ23_RS09685	COG0556	nucleotide-excision repair
CTZ23_RS09695	COG3706	GGDEF domain
CTZ23_RS09705	COG0436	Aminotransferase
CTZ23_RS09730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ23_RS09735	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ23_RS09745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ23_RS09750	COG0571	ribonuclease III activity
CTZ23_RS09760	COG0681	Belongs to the peptidase S26 family
CTZ23_RS09775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ23_RS09785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ23_RS09800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ23_RS09810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ23_RS09825	COG4208	sulfate ABC transporter
CTZ23_RS09830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ23_RS09835	COG0583	DNA-binding transcription factor activity
CTZ23_RS09845	COG4625	pathogenesis
CTZ23_RS09855	COG0602	queuosine metabolic process
CTZ23_RS09860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ23_RS09870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ23_RS09890	COG0583	DNA-binding transcription factor activity
CTZ23_RS09900	COG1056	cytidyltransferase-related domain
CTZ23_RS09900	COG1051	belongs to the nudix hydrolase family
CTZ23_RS09905	COG1024	Enoyl-CoA hydratase
CTZ23_RS09910	COG0778	Nitroreductase
CTZ23_RS09925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ23_RS09925	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ23_RS09945	COG2255	four-way junction helicase activity
CTZ23_RS09955	COG0824	Thioesterase
CTZ23_RS09975	COG0823	Involved in the tonB-independent uptake of proteins
CTZ23_RS09995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ23_RS10025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTZ23_RS10030	COG0628	permease
CTZ23_RS10035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CTZ23_RS10040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ23_RS10060	COG2333	competence protein COMEC
CTZ23_RS10060	COG0658	competence protein
CTZ23_RS10065	COG1136	(ABC) transporter
CTZ23_RS10070	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ23_RS10085	COG1671	Belongs to the UPF0178 family
CTZ23_RS10125	COG1280	lysine exporter protein (LysE YggA)
CTZ23_RS10130	COG1522	sequence-specific DNA binding
CTZ23_RS10140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ23_RS10155	COG0019	diaminopimelate decarboxylase activity
CTZ23_RS10165	COG1113	amino acid transport
CTZ23_RS10170	COG1115	amino acid carrier protein
CTZ23_RS10190	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ23_RS10195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ23_RS10230	COG0583	DNA-binding transcription factor activity
CTZ23_RS10240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ23_RS10250	COG0174	glutamine synthetase
CTZ23_RS10255	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ23_RS10275	COG0302	gtp cyclohydrolase
CTZ23_RS10315	COG3739	integral membrane protein
CTZ23_RS10320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CTZ23_RS10330	COG3385	transposase activity
CTZ23_RS10335	COG1741	Belongs to the pirin family
CTZ23_RS10340	COG3842	ATPase activity
CTZ23_RS10345	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ23_RS10375	COG0582	viral genome integration into host DNA
CTZ23_RS10405	COG2223	nitrite transmembrane transporter activity
CTZ23_RS10445	COG0798	PFAM Bile acid sodium symporter
CTZ23_RS10455	COG0640	Transcriptional regulator
CTZ23_RS10480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_RS10490	COG2184	nucleotidyltransferase activity
CTZ23_RS10535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ23_RS10540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTZ23_RS10550	COG0037	tRNA processing
CTZ23_RS10555	COG0739	heme binding
CTZ23_RS10555	COG1196	nuclear chromosome segregation
CTZ23_RS10555	COG0741	lytic transglycosylase activity
CTZ23_RS10560	COG0501	Belongs to the peptidase M48B family
CTZ23_RS10570	COG2239	Acts as a magnesium transporter
CTZ23_RS10580	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ23_RS10605	COG1597	lipid kinase activity
CTZ23_RS10625	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CTZ23_RS10660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ23_RS10675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ23_RS10680	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CTZ23_RS10685	COG1534	Rna-binding protein
CTZ23_RS10700	COG0505	Belongs to the CarA family
CTZ23_RS10735	COG0110	maltose O-acetyltransferase activity
CTZ23_RS10740	COG0589	response to stress
CTZ23_RS10750	COG2321	neutral zinc metallopeptidase
CTZ23_RS10755	COG2354	Protein conserved in bacteria
CTZ23_RS10780	COG2268	Band 7 protein
CTZ23_RS10790	COG1215	transferase activity, transferring glycosyl groups
CTZ23_RS10795	COG0726	polysaccharide deacetylase
CTZ23_RS10795	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ23_RS10805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CTZ23_RS10815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ23_RS10830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ23_RS10835	COG1053	succinate dehydrogenase
CTZ23_RS10840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ23_RS10855	COG2072	flavoprotein involved in K transport
CTZ23_RS10860	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS10870	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CTZ23_RS10875	COG0714	Associated with various cellular activities
CTZ23_RS10885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ23_RS10885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ23_RS10915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_RS10925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CTZ23_RS10940	COG0564	pseudouridine synthase activity
CTZ23_RS10950	COG0358	DNA primase activity
CTZ23_RS10965	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ23_RS10995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ23_RS11035	COG0586	Pfam SNARE associated Golgi protein
CTZ23_RS11070	COG0321	lipoyl(octanoyl) transferase activity
CTZ23_RS11090	COG0531	amino acid
CTZ23_RS11095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ23_RS11100	COG1648	precorrin-2 dehydrogenase activity
CTZ23_RS11100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ23_RS11105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CTZ23_RS11115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ23_RS11140	COG0671	phosphoesterase, PA-phosphatase related
CTZ23_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS11155	COG1538	Outer membrane efflux protein
CTZ23_RS11160	COG0393	Putative heavy-metal-binding
CTZ23_RS11165	COG0393	Putative heavy-metal-binding
CTZ23_RS11180	COG0525	valine-tRNA ligase activity
CTZ23_RS11205	COG2323	membrane
CTZ23_RS11215	COG0765	amino acid transport
CTZ23_RS11220	COG0765	amino acid transport
CTZ23_RS11225	COG1126	abc transporter atp-binding protein
CTZ23_RS11230	COG3338	carbonate dehydratase activity
CTZ23_RS11245	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ23_RS11260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_RS11265	COG2205	protein histidine kinase activity
CTZ23_RS11270	COG0745	RESPONSE REGULATOR receiver
CTZ23_RS11285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ23_RS11290	COG1652	LysM domain
CTZ23_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_RS11315	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ23_RS11320	COG3101	peptidyl-lysine hydroxylation
CTZ23_RS11325	COG0009	L-threonylcarbamoyladenylate synthase
CTZ23_RS11335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ23_RS11340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ23_RS11355	COG4106	trans-aconitate 2-methyltransferase activity
CTZ23_RS11370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_RS11370	COG0596	Alpha beta hydrolase
CTZ23_RS11370	COG2226	methyltransferase
CTZ23_RS11375	COG2193	ferroxidase activity
CTZ23_RS11380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTZ23_RS11385	COG3115	cell septum assembly
CTZ23_RS11390	COG1196	nuclear chromosome segregation
CTZ23_RS11400	COG0730	response to heat
CTZ23_RS11420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ23_RS11435	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CTZ23_RS11485	COG3328	transposase activity
CTZ23_RS11505	COG0628	permease
CTZ23_RS11515	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ23_RS11535	COG0564	pseudouridine synthase activity
CTZ23_RS11540	COG0346	lactoylglutathione lyase activity
CTZ23_RS11590	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ23_RS11620	COG0726	polysaccharide deacetylase
CTZ23_RS11620	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ23_RS11635	COG3328	transposase activity
CTZ23_RS11665	COG3177	Filamentation induced by cAMP protein fic
CTZ23_RS11690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ23_RS11695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTZ23_RS11720	COG0640	Transcriptional regulator
CTZ23_RS11735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ23_RS11750	COG0642	Histidine kinase
CTZ23_RS11830	COG0582	viral genome integration into host DNA
CTZ23_RS11840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ23_RS11845	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ23_RS11865	COG0420	3'-5' exonuclease activity
CTZ23_RS11895	COG0735	belongs to the Fur family
CTZ23_RS11900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_RS11905	COG2914	Belongs to the UPF0125 (RnfH) family
CTZ23_RS11920	COG0121	glutamine amidotransferase
CTZ23_RS11935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ23_RS11950	COG0210	DNA helicase
CTZ23_RS11955	COG2885	chlorophyll binding
CTZ23_RS11960	COG0204	Acyl-transferase
CTZ23_RS11970	COG0850	regulation of cytokinetic process
CTZ23_RS11975	COG2894	cell division
CTZ23_RS11990	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ23_RS11990	COG1674	ftsk spoiiie
CTZ23_RS11995	COG0492	ferredoxin-NADP+ reductase activity
CTZ23_RS12000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ23_RS12005	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CTZ23_RS12010	COG0456	acetyltransferase
CTZ23_RS12035	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CTZ23_RS12050	COG1981	membrane
CTZ23_RS12055	COG1113	amino acid transport
CTZ23_RS12060	COG0251	oxidation-reduction process
CTZ23_RS12085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ23_RS12085	COG0352	thiamine-phosphate diphosphorylase activity
CTZ23_RS12085	COG0351	phosphomethylpyrimidine kinase
CTZ23_RS12100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ23_RS12120	COG2132	Multicopper oxidase
CTZ23_RS12130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ23_RS12145	COG4269	membrane
CTZ23_RS12165	COG1968	undecaprenyl-diphosphatase activity
CTZ23_RS12170	COG1214	PFAM Peptidase M22, glycoprotease
CTZ23_RS12180	COG0494	nUDIX hydrolase
CTZ23_RS12230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ23_RS12235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ23_RS12320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ23_RS12365	COG0037	tRNA processing
CTZ23_RS12375	COG0248	Ppx GppA phosphatase
CTZ23_RS12400	COG0072	phenylalanine-tRNA ligase activity
CTZ23_RS12435	COG1238	metal cluster binding
CTZ23_RS12440	COG0625	glutathione transferase activity
CTZ23_RS12465	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS12470	COG3028	Belongs to the UPF0307 family
CTZ23_RS12480	COG1660	Displays ATPase and GTPase activities
CTZ23_RS12495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ23_RS12500	COG0617	tRNA 3'-terminal CCA addition
CTZ23_RS12505	COG1555	photosystem II stabilization
CTZ23_RS12510	COG3956	TIGRFAM MazG family protein
CTZ23_RS12525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_RS12535	COG0124	histidyl-tRNA synthetase
CTZ23_RS12565	COG2975	iron-sulfur cluster assembly
CTZ23_RS12605	COG0440	acetolactate synthase activity
CTZ23_RS12610	COG0028	Belongs to the TPP enzyme family
CTZ23_RS12635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS12640	COG0577	efflux transmembrane transporter activity
CTZ23_RS12640	COG1136	(ABC) transporter
CTZ23_RS12645	COG1538	Outer membrane efflux protein
CTZ23_RS12680	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ23_RS12685	COG1162	GTPase activity
CTZ23_RS12695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ23_RS12705	COG3385	transposase activity
CTZ23_RS12710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ23_RS12720	COG3781	membrane
CTZ23_RS12735	COG2350	Protein conserved in bacteria
CTZ23_RS12755	COG1666	GTP binding
CTZ23_RS12765	COG1607	acyl-coa hydrolase
CTZ23_RS12830	COG1183	phosphatidylcholine synthase activity
CTZ23_RS12835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ23_RS12875	COG3385	transposase activity
CTZ23_RS12890	COG0741	lytic transglycosylase activity
CTZ23_RS12890	COG1196	nuclear chromosome segregation
CTZ23_RS12890	COG0739	heme binding
CTZ23_RS12900	COG1702	phosphate starvation-inducible protein PhoH
CTZ23_RS12950	COG1295	ribonuclease BN
CTZ23_RS12980	COG0788	formyltetrahydrofolate deformylase activity
CTZ23_RS13005	COG4651	solute:proton antiporter activity
CTZ23_RS13005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ23_RS13020	COG0724	RNA recognition motif
CTZ23_RS13025	COG0210	DNA helicase
CTZ23_RS13035	COG1929	Belongs to the glycerate kinase type-1 family
CTZ23_RS13065	COG2900	Belongs to the SlyX family
CTZ23_RS13070	COG0488	(ABC) transporter
CTZ23_RS13075	COG1560	Kdo2-lipid A biosynthetic process
CTZ23_RS13125	COG0473	3-isopropylmalate dehydrogenase activity
CTZ23_RS13140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CTZ23_RS13160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ23_RS13175	COG0494	nUDIX hydrolase
CTZ23_RS13195	COG1960	acyl-CoA dehydrogenase activity
CTZ23_RS13205	COG0753	catalase activity
CTZ23_RS13220	COG0583	DNA-binding transcription factor activity
CTZ23_RS13225	COG0546	phosphoglycolate phosphatase activity
CTZ23_RS13240	COG1530	ribonuclease E activity
CTZ23_RS13245	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS13270	COG1983	PspC domain protein
CTZ23_RS13275	COG0617	tRNA 3'-terminal CCA addition
CTZ23_RS13275	COG0517	IMP dehydrogenase activity
CTZ23_RS13275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTZ23_RS13285	COG0751	glycine-tRNA ligase activity
CTZ23_RS13315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTZ23_RS13330	COG2226	methyltransferase
CTZ23_RS13340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_RS13340	COG0493	'glutamate synthase
CTZ23_RS13350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ23_RS13360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ23_RS13375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ23_RS13385	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ23_RS13385	COG0644	oxidoreductase
CTZ23_RS13405	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ23_RS13410	COG4535	Mg2 and Co2 transporter CorC
CTZ23_RS13415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CTZ23_RS13435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ23_RS13445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ23_RS13455	COG0789	Transcriptional regulator
CTZ23_RS13460	COG2841	Protein conserved in bacteria
CTZ23_RS13475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTZ23_RS13480	COG0675	Transposase, IS605 OrfB family
CTZ23_RS13485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ23_RS13490	COG1074	ATP-dependent DNA helicase activity
CTZ23_RS13495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ23_RS13525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ23_RS13535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ23_RS13550	COG2111	Na H antiporter
CTZ23_RS13550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ23_RS13555	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ23_RS13560	COG0651	ATP synthesis coupled electron transport
CTZ23_RS13565	COG1863	multisubunit Na H antiporter MnhE subunit
CTZ23_RS13570	COG2212	antiporter activity
CTZ23_RS13575	COG1320	monovalent cation:proton antiporter activity
CTZ23_RS13580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CTZ23_RS13590	COG0195	Participates in both transcription termination and antitermination
CTZ23_RS13595	COG0779	Required for maturation of 30S ribosomal subunits
CTZ23_RS13645	COG0237	dephospho-CoA kinase activity
CTZ23_RS13655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ23_RS13660	COG3123	guanosine phosphorylase activity
CTZ23_RS13665	COG0497	DNA recombination
CTZ23_RS13675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ23_RS13690	COG1132	(ABC) transporter
CTZ23_RS13695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ23_RS13725	COG1024	Enoyl-CoA hydratase
CTZ23_RS13725	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_RS13745	COG2233	PERMEase
CTZ23_RS13755	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ23_RS13780	COG0326	Molecular chaperone. Has ATPase activity
CTZ23_RS13795	COG2056	Na+-H+ antiporter family
CTZ23_RS13815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CTZ23_RS13820	COG0085	RNA polymerase activity
CTZ23_RS13835	COG0081	regulation of translation
CTZ23_RS13890	COG0546	phosphoglycolate phosphatase activity
CTZ23_RS13920	COG0824	Thioesterase
CTZ23_RS13940	COG0181	hydroxymethylbilane synthase activity
CTZ23_RS13950	COG3275	phosphorelay sensor kinase activity
CTZ23_RS13985	COG0494	nUDIX hydrolase
CTZ23_RS13990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ23_RS13995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ23_RS14000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ23_RS14010	COG0772	Belongs to the SEDS family
CTZ23_RS14035	COG4974	Belongs to the 'phage' integrase family
CTZ23_RS14050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ23_RS14060	COG2197	response regulator
CTZ23_RS14075	COG0793	Belongs to the peptidase S41A family
CTZ23_RS14080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ23_RS14085	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ23_RS14090	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ23_RS14115	COG0586	Pfam SNARE associated Golgi protein
CTZ23_RS14130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ23_RS14130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ23_RS14140	COG0004	ammonium transporteR
CTZ23_RS14145	COG0347	Belongs to the P(II) protein family
CTZ23_RS14205	COG3293	Transposase
CTZ23_RS14230	COG3293	Transposase
CTZ23_RS14245	COG2826	transposase and inactivated derivatives, IS30 family
CTZ23_RS14250	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CTZ23_RS14260	COG2826	transposase and inactivated derivatives, IS30 family
CTZ23_RS14300	COG0606	chelatase, subunit chli
CTZ23_RS14315	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ23_RS14330	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_RS14340	COG0477	Major facilitator Superfamily
CTZ23_RS14345	COG2860	membrane
CTZ23_RS14355	COG1253	flavin adenine dinucleotide binding
CTZ23_RS14375	COG2814	Major facilitator Superfamily
CTZ23_RS14390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ23_RS14415	COG2814	Major facilitator Superfamily
CTZ23_RS14465	COG0758	DNA mediated transformation
CTZ23_RS14480	COG0697	spore germination
CTZ23_RS14485	COG0386	Belongs to the glutathione peroxidase family
CTZ23_RS14520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CTZ23_RS14570	COG1121	(ABC) transporter
CTZ23_RS14575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ23_RS14585	COG2837	iron assimilation
CTZ23_RS14610	COG0281	malic enzyme
CTZ23_RS14655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ23_RS14655	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ23_RS14660	COG2259	Doxx family
CTZ23_RS14665	COG0586	Pfam SNARE associated Golgi protein
CTZ23_RS14680	COG1192	Involved in chromosome partitioning
CTZ23_RS14690	COG0271	Belongs to the BolA IbaG family
CTZ23_RS14715	COG3550	peptidyl-serine autophosphorylation
CTZ23_RS14720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTZ23_RS14745	COG4628	conserved protein (DUF2132)
CTZ23_RS14755	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CTZ23_RS14770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ23_RS14780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ23_RS14800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ23_RS14810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTZ23_RS14820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ23_RS14840	COG1086	Polysaccharide biosynthesis protein
CTZ23_RS14855	COG0110	maltose O-acetyltransferase activity
CTZ23_RS14880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ23_RS14935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_RS14940	COG1309	transcriptional regulator
CTZ23_RS14950	COG2233	PERMEase
CTZ23_RS14965	COG0129	dihydroxy-acid dehydratase activity
CTZ23_RS14980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTZ23_RS14990	COG0733	neurotransmitter:sodium symporter activity
CTZ23_RS14995	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_RS15005	COG3385	transposase activity
CTZ23_RS15010	COG2814	Major facilitator Superfamily
CTZ23_RS15040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ23_RS15050	COG0657	acetylesterase activity
CTZ23_RS15085	COG2951	lytic endotransglycosylase activity
CTZ23_RS15095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ23_RS15115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ23_RS15130	COG2388	GCN5-related N-acetyl-transferase
CTZ23_RS15140	COG0861	Integral membrane protein TerC family
CTZ23_RS15145	COG0402	S-adenosylhomocysteine deaminase activity
CTZ23_RS15155	COG0675	Transposase, IS605 OrfB family
CTZ23_RS15165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ23_RS15170	COG1230	cation diffusion facilitator family transporter
CTZ23_RS15195	COG0706	membrane insertase activity
CTZ23_RS15200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CTZ23_RS15205	COG0594	ribonuclease P activity