locus-tag	class	description
GA660_RS00010	COG2233	PERMEase
GA660_RS00025	COG0129	dihydroxy-acid dehydratase activity
GA660_RS00035	COG0129	dihydroxy-acid dehydratase activity
GA660_RS00045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GA660_RS00055	COG0733	neurotransmitter:sodium symporter activity
GA660_RS00060	COG1012	belongs to the aldehyde dehydrogenase family
GA660_RS00085	COG2814	Major facilitator Superfamily
GA660_RS00115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GA660_RS00160	COG2951	lytic endotransglycosylase activity
GA660_RS00170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GA660_RS00190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GA660_RS00200	COG2388	GCN5-related N-acetyl-transferase
GA660_RS00210	COG0861	Integral membrane protein TerC family
GA660_RS00215	COG0402	S-adenosylhomocysteine deaminase activity
GA660_RS00230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GA660_RS00235	COG1230	cation diffusion facilitator family transporter
GA660_RS00260	COG0706	membrane insertase activity
GA660_RS00265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GA660_RS00270	COG0594	ribonuclease P activity
GA660_RS00275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GA660_RS00280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GA660_RS00285	COG0592	DNA-directed DNA polymerase activity
GA660_RS00295	COG0187	DNA topoisomerase II activity
GA660_RS00300	COG1063	alcohol dehydrogenase
GA660_RS00305	COG0488	(ABC) transporter
GA660_RS00315	COG1943	Transposase
GA660_RS00345	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GA660_RS00350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GA660_RS00360	COG0737	Belongs to the 5'-nucleotidase family
GA660_RS00390	COG2814	Major facilitator Superfamily
GA660_RS00395	COG2133	pyrroloquinoline quinone binding
GA660_RS00405	COG1047	Peptidyl-prolyl cis-trans
GA660_RS00410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GA660_RS00415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GA660_RS00420	COG0196	riboflavin kinase activity
GA660_RS00430	COG1309	transcriptional regulator
GA660_RS00435	COG1116	anion transmembrane transporter activity
GA660_RS00440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GA660_RS00445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GA660_RS00450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GA660_RS00455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GA660_RS00460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GA660_RS00460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GA660_RS00490	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS00495	COG0546	phosphoglycolate phosphatase activity
GA660_RS00500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GA660_RS00510	COG1309	transcriptional regulator
GA660_RS00515	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GA660_RS00525	COG3023	N-Acetylmuramoyl-L-alanine amidase
GA660_RS00545	COG1064	alcohol dehydrogenase
GA660_RS00550	COG2818	Glycosylase
GA660_RS00560	COG0739	heme binding
GA660_RS00565	COG1194	a g-specific adenine glycosylase
GA660_RS00580	COG5487	UPF0391 membrane protein
GA660_RS00585	COG2983	Belongs to the UPF0260 family
GA660_RS00590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GA660_RS00595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GA660_RS00605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GA660_RS00610	COG2814	Major facilitator Superfamily
GA660_RS00615	COG1335	isochorismatase
GA660_RS00620	COG0385	Bile acid
GA660_RS00635	COG0560	Phosphoserine phosphatase
GA660_RS00635	COG3830	Belongs to the UPF0237 family
GA660_RS00655	COG0753	catalase activity
GA660_RS00700	COG2175	clavaminate synthase activity
GA660_RS00705	COG0534	Mate efflux family protein
GA660_RS00710	COG0436	Aminotransferase
GA660_RS00715	COG2733	membrane
GA660_RS00730	COG2918	glutathione biosynthetic process
GA660_RS00735	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GA660_RS00745	COG3150	esterase
GA660_RS00760	COG0559	Belongs to the binding-protein-dependent transport system permease family
GA660_RS00775	COG0410	ABC transporter
GA660_RS00785	COG0471	metal ion transport
GA660_RS00800	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GA660_RS00805	COG4266	Belongs to the allantoicase family
GA660_RS00810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA660_RS00815	COG1247	-acetyltransferase
GA660_RS00855	COG0625	glutathione transferase activity
GA660_RS00860	COG3706	GGDEF domain
GA660_RS00865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GA660_RS00880	COG1393	Belongs to the ArsC family
GA660_RS00885	COG0708	Exodeoxyribonuclease III
GA660_RS00905	COG0189	ligase activity
GA660_RS00910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GA660_RS00915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GA660_RS00925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GA660_RS00935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GA660_RS00965	COG2119	membrane
GA660_RS00970	COG0426	domain, Protein
GA660_RS00970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GA660_RS00995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GA660_RS01015	COG1902	pentaerythritol trinitrate reductase activity
GA660_RS01020	COG1519	Transferase
GA660_RS01025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GA660_RS01030	COG0668	transmembrane transport
GA660_RS01035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GA660_RS01045	COG0431	NADPH-dependent FMN reductase
GA660_RS01060	COG2205	protein histidine kinase activity
GA660_RS01060	COG0784	Response regulator, receiver
GA660_RS01065	COG3162	membrane
GA660_RS01070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GA660_RS01085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GA660_RS01095	COG3706	GGDEF domain
GA660_RS01100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GA660_RS01105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GA660_RS01115	COG2814	Major facilitator Superfamily
GA660_RS01120	COG0629	single-stranded DNA binding
GA660_RS01180	COG2132	Multicopper oxidase
GA660_RS01195	COG2205	protein histidine kinase activity
GA660_RS01200	COG3174	membrane
GA660_RS01205	COG2217	Heavy metal translocating P-type atpase
GA660_RS01250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GA660_RS01335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GA660_RS01370	COG2132	Multicopper oxidase
GA660_RS01385	COG3077	Addiction module antitoxin, RelB DinJ family
GA660_RS01405	COG0450	alkyl hydroperoxide reductase
GA660_RS01415	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GA660_RS01440	COG3158	transport of potassium into the cell
GA660_RS01480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GA660_RS01495	COG0697	spore germination
GA660_RS01515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GA660_RS01545	COG0427	acetyl-CoA hydrolase
GA660_RS01550	COG2205	protein histidine kinase activity
GA660_RS01555	COG0745	RESPONSE REGULATOR receiver
GA660_RS01570	COG4221	oxidoreductase activity
GA660_RS01580	COG0488	(ABC) transporter
GA660_RS01600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GA660_RS01610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GA660_RS01615	COG0275	rRNA processing
GA660_RS01630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GA660_RS01635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GA660_RS01645	COG2226	methyltransferase
GA660_RS01695	COG0070	glutamate synthase
GA660_RS01695	COG0069	glutamate synthase activity
GA660_RS01695	COG0067	glutamate synthase
GA660_RS01700	COG0493	'glutamate synthase
GA660_RS01705	COG1704	LemA family
GA660_RS01735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GA660_RS01735	COG2755	lipolytic protein G-D-S-L family
GA660_RS01745	COG3307	-O-antigen
GA660_RS01755	COG2906	2 iron, 2 sulfur cluster binding
GA660_RS01765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GA660_RS01770	COG1758	RNA polymerase activity
GA660_RS01775	COG0194	GDP metabolic process
GA660_RS01820	COG0228	four-way junction DNA binding
GA660_RS01825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GA660_RS01835	COG0335	large ribosomal subunit rRNA binding
GA660_RS01860	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GA660_RS01865	COG5380	lipid catabolic process
GA660_RS01870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GA660_RS01895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GA660_RS01900	COG0277	FAD linked oxidase domain protein
GA660_RS01915	COG2814	Major facilitator Superfamily
GA660_RS01925	COG0628	permease
GA660_RS01930	COG1192	Involved in chromosome partitioning
GA660_RS01970	COG1943	Transposase
GA660_RS01975	COG2226	methyltransferase
GA660_RS01995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GA660_RS02000	COG0254	rRNA binding
GA660_RS02005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GA660_RS02010	COG0534	Mate efflux family protein
GA660_RS02020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GA660_RS02025	COG1960	acyl-CoA dehydrogenase activity
GA660_RS02040	COG0408	coproporphyrinogen oxidase activity
GA660_RS02045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GA660_RS02070	COG1127	ABC transporter
GA660_RS02075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GA660_RS02080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GA660_RS02085	COG2854	intermembrane phospholipid transfer
GA660_RS02095	COG0598	Magnesium transport protein CorA
GA660_RS02110	COG1040	competence protein
GA660_RS02115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GA660_RS02125	COG2937	Belongs to the GPAT DAPAT family
GA660_RS02130	COG1946	Acyl-CoA thioesterase
GA660_RS02135	COG1301	dicarboxylic acid transport
GA660_RS02155	COG1959	2 iron, 2 sulfur cluster binding
GA660_RS02160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GA660_RS02160	COG1017	nitric oxide dioxygenase activity
GA660_RS02165	COG0433	COG0433 Predicted ATPase
GA660_RS02190	COG0088	Forms part of the polypeptide exit tunnel
GA660_RS02220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GA660_RS02245	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GA660_RS02255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GA660_RS02260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GA660_RS02270	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GA660_RS02290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GA660_RS02300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GA660_RS02305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GA660_RS02310	COG0202	RNA polymerase activity
GA660_RS02320	COG2072	flavoprotein involved in K transport
GA660_RS02325	COG1960	acyl-CoA dehydrogenase activity
GA660_RS02330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GA660_RS02355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GA660_RS02370	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GA660_RS02375	COG0339	signal peptide processing
GA660_RS02380	COG0557	exoribonuclease II activity
GA660_RS02415	COG0179	Fumarylacetoacetate (FAA) hydrolase
GA660_RS02445	COG3040	lipid binding
GA660_RS02505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA660_RS02505	COG2813	Specifically methylates the guanine in position
GA660_RS02510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA660_RS02515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GA660_RS02525	COG3128	pkhd-type hydroxylase
GA660_RS02530	COG4774	siderophore transport
GA660_RS02535	COG4771	TonB-dependent receptor
GA660_RS02545	COG0740	serine-type endopeptidase activity
GA660_RS02560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GA660_RS02560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GA660_RS02570	COG0280	phosphate acetyltransferase
GA660_RS02570	COG0857	belongs to the CobB CobQ family
GA660_RS02575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GA660_RS02605	COG0793	Belongs to the peptidase S41A family
GA660_RS02620	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GA660_RS02635	COG0084	hydrolase, TatD family'
GA660_RS02640	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GA660_RS02645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GA660_RS02675	COG1846	Transcriptional regulator
GA660_RS02680	COG1024	Enoyl-CoA hydratase
GA660_RS02685	COG2814	Major facilitator Superfamily
GA660_RS02705	COG0183	Belongs to the thiolase family
GA660_RS02710	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA660_RS02715	COG1024	Enoyl-CoA hydratase
GA660_RS02720	COG1960	acyl-CoA dehydrogenase activity
GA660_RS02725	COG1960	acyl-CoA dehydrogenase activity
GA660_RS02735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GA660_RS02745	COG0318	PFAM AMP-dependent synthetase and ligase
GA660_RS02770	COG1058	Belongs to the CinA family
GA660_RS02770	COG1546	Belongs to the CinA family
GA660_RS02790	COG2814	Major facilitator Superfamily
GA660_RS02795	COG0697	spore germination
GA660_RS02800	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GA660_RS02805	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GA660_RS02810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GA660_RS02820	COG3622	Belongs to the hyi family
GA660_RS02830	COG1024	Enoyl-CoA hydratase
GA660_RS02835	COG0784	Response regulator, receiver
GA660_RS02835	COG2205	protein histidine kinase activity
GA660_RS02835	COG5002	protein histidine kinase activity
GA660_RS02840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GA660_RS02855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GA660_RS02865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GA660_RS02875	COG1862	Preprotein translocase
GA660_RS02885	COG3706	GGDEF domain
GA660_RS02885	COG2203	Gaf domain
GA660_RS02885	COG5001	Diguanylate cyclase
GA660_RS02885	COG4251	negative regulation of phosphorylation
GA660_RS02890	COG1704	LemA family
GA660_RS02900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GA660_RS02915	COG5002	protein histidine kinase activity
GA660_RS02920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GA660_RS02950	COG0463	Glycosyl transferase, family 2
GA660_RS02965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GA660_RS02995	COG3223	Belongs to the PsiE family
GA660_RS03000	COG1960	acyl-CoA dehydrogenase activity
GA660_RS03005	COG1960	acyl-CoA dehydrogenase activity
GA660_RS03015	COG2205	protein histidine kinase activity
GA660_RS03020	COG0745	RESPONSE REGULATOR receiver
GA660_RS03030	COG2315	Protein conserved in bacteria
GA660_RS03035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GA660_RS03055	COG2096	Adenosyltransferase
GA660_RS03060	COG4206	TonB-dependent receptor
GA660_RS03070	COG0133	tryptophan synthase activity
GA660_RS03105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GA660_RS03110	COG0285	dihydrofolate synthase activity
GA660_RS03125	COG0450	alkyl hydroperoxide reductase
GA660_RS03140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GA660_RS03145	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GA660_RS03175	COG2199	diguanylate cyclase activity
GA660_RS03240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GA660_RS03245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GA660_RS03295	COG0494	nUDIX hydrolase
GA660_RS03305	COG1214	PFAM Peptidase M22, glycoprotease
GA660_RS03310	COG1968	undecaprenyl-diphosphatase activity
GA660_RS03330	COG4269	membrane
GA660_RS03345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GA660_RS03355	COG2132	Multicopper oxidase
GA660_RS03370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GA660_RS03385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GA660_RS03385	COG0351	phosphomethylpyrimidine kinase
GA660_RS03385	COG0352	thiamine-phosphate diphosphorylase activity
GA660_RS03395	COG1522	sequence-specific DNA binding
GA660_RS03410	COG0251	oxidation-reduction process
GA660_RS03415	COG1113	amino acid transport
GA660_RS03435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GA660_RS03460	COG0456	acetyltransferase
GA660_RS03470	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GA660_RS03475	COG0492	ferredoxin-NADP+ reductase activity
GA660_RS03480	COG1674	ftsk spoiiie
GA660_RS03480	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GA660_RS03495	COG2894	cell division
GA660_RS03500	COG0850	regulation of cytokinetic process
GA660_RS03510	COG0204	Acyl-transferase
GA660_RS03515	COG2885	chlorophyll binding
GA660_RS03520	COG0210	DNA helicase
GA660_RS03525	COG0756	dUTP diphosphatase activity
GA660_RS03530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GA660_RS03545	COG0121	glutamine amidotransferase
GA660_RS03560	COG2914	Belongs to the UPF0125 (RnfH) family
GA660_RS03565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA660_RS03570	COG0735	belongs to the Fur family
GA660_RS03600	COG0420	3'-5' exonuclease activity
GA660_RS03620	COG2050	protein possibly involved in aromatic compounds catabolism
GA660_RS03625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GA660_RS03635	COG0582	viral genome integration into host DNA
GA660_RS03675	COG2184	nucleotidyltransferase activity
GA660_RS03700	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GA660_RS03740	COG3188	usher protein
GA660_RS03755	COG3177	Filamentation induced by cAMP protein fic
GA660_RS03775	COG0726	polysaccharide deacetylase
GA660_RS03775	COG1649	PFAM Uncharacterised BCR, COG1649
GA660_RS03780	COG1215	transferase activity, transferring glycosyl groups
GA660_RS03795	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GA660_RS03820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GA660_RS03825	COG0154	amidase activity
GA660_RS03830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GA660_RS03835	COG1077	Cell shape determining protein MreB Mrl
GA660_RS03840	COG1792	Involved in formation and maintenance of cell shape
GA660_RS03845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GA660_RS03850	COG0424	maF-like protein
GA660_RS03855	COG1530	ribonuclease E activity
GA660_RS03875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GA660_RS03915	COG0625	glutathione transferase activity
GA660_RS03935	COG1113	amino acid transport
GA660_RS03940	COG2828	Protein conserved in bacteria
GA660_RS03945	COG0142	geranyltranstransferase activity
GA660_RS03955	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GA660_RS03975	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GA660_RS03985	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GA660_RS03990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GA660_RS03995	COG0839	Belongs to the complex I subunit 6 family
GA660_RS04000	COG0713	ATP synthesis coupled electron transport
GA660_RS04005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GA660_RS04010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GA660_RS04025	COG1278	Cold shock
GA660_RS04035	COG0583	DNA-binding transcription factor activity
GA660_RS04060	COG0668	transmembrane transport
GA660_RS04070	COG2081	HI0933 family
GA660_RS04090	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GA660_RS04130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GA660_RS04130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GA660_RS04135	COG0489	protein tyrosine kinase activity
GA660_RS04185	COG0442	prolyl-tRNA aminoacylation
GA660_RS04220	COG0840	transmembrane signaling receptor activity
GA660_RS04240	COG5510	response to toxic substance
GA660_RS04250	COG2832	Protein of unknown function (DUF454)
GA660_RS04255	COG1376	ErfK ybiS ycfS ynhG family protein
GA660_RS04310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GA660_RS04320	COG1289	transmembrane transporter activity
GA660_RS04325	COG2814	Major facilitator Superfamily
GA660_RS04340	COG0786	glutamate:sodium symporter activity
GA660_RS04345	COG1115	amino acid carrier protein
GA660_RS04350	COG2059	Chromate
GA660_RS04355	COG1752	Esterase of the alpha-beta hydrolase superfamily
GA660_RS04365	COG1607	acyl-coa hydrolase
GA660_RS04370	COG1309	transcriptional regulator
GA660_RS04375	COG2814	Major facilitator Superfamily
GA660_RS04380	COG0583	DNA-binding transcription factor activity
GA660_RS04400	COG0523	cobalamin synthesis protein
GA660_RS04405	COG4681	YaeQ
GA660_RS04415	COG2199	diguanylate cyclase activity
GA660_RS04415	COG2203	Gaf domain
GA660_RS04470	COG2066	Belongs to the glutaminase family
GA660_RS04480	COG0306	phosphate transporter
GA660_RS04505	COG4771	TonB-dependent receptor
GA660_RS04530	COG4181	ATPase activity
GA660_RS04535	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GA660_RS04545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GA660_RS04555	COG0583	DNA-binding transcription factor activity
GA660_RS04565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA660_RS04570	COG1773	rubredoxin
GA660_RS04575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GA660_RS04595	COG0175	sulfate reduction
GA660_RS04605	COG3118	belongs to the thioredoxin family
GA660_RS04625	COG1253	flavin adenine dinucleotide binding
GA660_RS04645	COG3015	lipoprotein NlpE involved in copper resistance
GA660_RS04650	COG0204	Acyl-transferase
GA660_RS04660	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS04680	COG0804	urea catabolic process
GA660_RS04695	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GA660_RS04700	COG0830	nickel cation binding
GA660_RS04715	COG0742	ribosomal rna small subunit methyltransferase
GA660_RS04720	COG0768	penicillin binding
GA660_RS04745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GA660_RS04750	COG2878	Part of a membrane complex involved in electron transport
GA660_RS04755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GA660_RS04765	COG3384	dioxygenase
GA660_RS04775	COG2234	aminopeptidase activity
GA660_RS04785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GA660_RS04800	COG3706	GGDEF domain
GA660_RS04800	COG0745	RESPONSE REGULATOR receiver
GA660_RS04820	COG3079	Belongs to the UPF0149 family
GA660_RS04825	COG0006	proline dipeptidase activity
GA660_RS04835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA660_RS04840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA660_RS04885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GA660_RS04890	COG1388	LysM domain
GA660_RS04890	COG0741	lytic transglycosylase activity
GA660_RS04895	COG4166	transmembrane transport
GA660_RS04900	COG4174	ABC transporter (Permease)
GA660_RS04905	COG4239	(ABC) transporter, permease
GA660_RS04910	COG4172	Belongs to the ABC transporter superfamily
GA660_RS04940	COG0833	amino acid
GA660_RS04960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GA660_RS04965	COG0418	dihydroorotase activity
GA660_RS04970	COG5001	Diguanylate cyclase
GA660_RS04970	COG3706	GGDEF domain
GA660_RS04970	COG4251	negative regulation of phosphorylation
GA660_RS04970	COG2203	Gaf domain
GA660_RS04985	COG0446	pyridine nucleotide-disulphide oxidoreductase
GA660_RS04985	COG1902	pentaerythritol trinitrate reductase activity
GA660_RS05000	COG1228	amidohydrolase
GA660_RS05010	COG3293	Transposase
GA660_RS05030	COG2885	chlorophyll binding
GA660_RS05030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GA660_RS05070	COG2871	sodium ion transport
GA660_RS05100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GA660_RS05120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GA660_RS05125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GA660_RS05130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GA660_RS05140	COG1473	amidohydrolase
GA660_RS05155	COG1960	acyl-CoA dehydrogenase activity
GA660_RS05160	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GA660_RS05170	COG2175	clavaminate synthase activity
GA660_RS05185	COG0024	Methionine aminopeptidase
GA660_RS05190	COG0052	Belongs to the universal ribosomal protein uS2 family
GA660_RS05215	COG2951	lytic endotransglycosylase activity
GA660_RS05230	COG0842	Transport permease protein
GA660_RS05235	COG1131	(ABC) transporter
GA660_RS05290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GA660_RS05310	COG3634	alkyl hydroperoxide reductase activity
GA660_RS05315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GA660_RS05330	COG0640	Transcriptional regulator
GA660_RS05340	COG0798	PFAM Bile acid sodium symporter
GA660_RS05345	COG0431	NADPH-dependent FMN reductase
GA660_RS05350	COG0789	Transcriptional regulator
GA660_RS05375	COG1720	tRNA m6t6A37 methyltransferase activity
GA660_RS05390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GA660_RS05400	COG0745	RESPONSE REGULATOR receiver
GA660_RS05405	COG0642	Histidine kinase
GA660_RS05425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GA660_RS05430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GA660_RS05435	COG3139	Protein of unknown function (DUF1315)
GA660_RS05450	COG1301	dicarboxylic acid transport
GA660_RS05455	COG1960	acyl-CoA dehydrogenase activity
GA660_RS05460	COG0693	protein deglycase activity
GA660_RS05470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GA660_RS05475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GA660_RS05500	COG1047	Peptidyl-prolyl cis-trans
GA660_RS05505	COG1252	NADH dehydrogenase
GA660_RS05510	COG1686	Belongs to the peptidase S11 family
GA660_RS05525	COG1187	pseudouridine synthase activity
GA660_RS05535	COG0739	heme binding
GA660_RS05545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GA660_RS05555	COG0612	Peptidase, M16
GA660_RS05590	COG0352	thiamine-phosphate diphosphorylase activity
GA660_RS05605	COG2801	Transposase and inactivated derivatives
GA660_RS05610	COG3328	transposase activity
GA660_RS05640	COG0596	Alpha beta hydrolase
GA660_RS05645	COG1309	transcriptional regulator
GA660_RS05680	COG1278	Cold shock
GA660_RS05690	COG0675	Transposase, IS605 OrfB family
GA660_RS05700	COG2070	2-Nitropropane dioxygenase
GA660_RS05725	COG2391	methyltransferase activity
GA660_RS05730	COG3293	Transposase
GA660_RS05740	COG3634	alkyl hydroperoxide reductase activity
GA660_RS05765	COG0450	alkyl hydroperoxide reductase
GA660_RS05770	COG1643	Atp-dependent helicase
GA660_RS05795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GA660_RS05795	COG0517	IMP dehydrogenase activity
GA660_RS05800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GA660_RS05810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GA660_RS05815	COG1137	ATPase activity
GA660_RS05850	COG4122	O-methyltransferase activity
GA660_RS05860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GA660_RS05875	COG1454	alcohol dehydrogenase
GA660_RS05905	COG2011	ABC-type metal ion transport system permease component
GA660_RS05910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GA660_RS05930	COG0138	bifunctional purine biosynthesis protein purh
GA660_RS05935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GA660_RS05975	COG2308	Evidence 4 Homologs of previously reported genes of
GA660_RS05985	COG1305	Transglutaminase-like
GA660_RS06000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GA660_RS06005	COG0305	Participates in initiation and elongation during chromosome replication
GA660_RS06015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GA660_RS06020	COG0360	Binds together with S18 to 16S ribosomal RNA
GA660_RS06030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GA660_RS06035	COG1845	cytochrome c oxidase, subunit III
GA660_RS06040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GA660_RS06045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GA660_RS06070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GA660_RS06085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GA660_RS06095	COG3781	membrane
GA660_RS06115	COG1960	acyl-CoA dehydrogenase activity
GA660_RS06120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GA660_RS06130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GA660_RS06140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GA660_RS06150	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GA660_RS06155	COG0477	Major facilitator Superfamily
GA660_RS06220	COG0308	aminopeptidase N
GA660_RS06230	COG0589	response to stress
GA660_RS06235	COG0589	response to stress
GA660_RS06245	COG3135	benzoate transporter
GA660_RS06255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GA660_RS06270	COG0183	Belongs to the thiolase family
GA660_RS06295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GA660_RS06300	COG0824	Thioesterase
GA660_RS06305	COG1454	alcohol dehydrogenase
GA660_RS06310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GA660_RS06330	COG0069	glutamate synthase activity
GA660_RS06340	COG4585	Histidine kinase
GA660_RS06345	COG2850	peptidyl-arginine hydroxylation
GA660_RS06350	COG0424	maF-like protein
GA660_RS06375	COG0697	spore germination
GA660_RS06415	COG3698	Phosphodiester glycosidase
GA660_RS06435	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GA660_RS06435	COG0506	proline dehydrogenase activity
GA660_RS06435	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GA660_RS06445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GA660_RS06450	COG1027	Aspartate ammonia-lyase
GA660_RS06455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GA660_RS06460	COG0583	DNA-binding transcription factor activity
GA660_RS06465	COG1960	acyl-CoA dehydrogenase activity
GA660_RS06470	COG2814	Major facilitator Superfamily
GA660_RS06475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GA660_RS06490	COG1902	pentaerythritol trinitrate reductase activity
GA660_RS06490	COG0446	pyridine nucleotide-disulphide oxidoreductase
GA660_RS06520	COG0148	phosphopyruvate hydratase activity
GA660_RS06535	COG0772	Belongs to the SEDS family
GA660_RS06550	COG2137	regulation of response to DNA damage stimulus
GA660_RS06560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GA660_RS06565	COG1011	Hydrolase
GA660_RS06570	COG1218	3'(2'),5'-bisphosphate nucleotidase
GA660_RS06585	COG0268	Binds directly to 16S ribosomal RNA
GA660_RS06590	COG0702	epimerase
GA660_RS06595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GA660_RS06610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GA660_RS06640	COG0316	Belongs to the HesB IscA family
GA660_RS06645	COG0822	iron-sulfur transferase activity
GA660_RS06675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GA660_RS06730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GA660_RS06750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GA660_RS06760	COG0133	tryptophan synthase activity
GA660_RS06765	COG0517	IMP dehydrogenase activity
GA660_RS06765	COG0516	GMP reductase activity
GA660_RS06795	COG0612	Peptidase, M16
GA660_RS06800	COG0552	protein localization to endoplasmic reticulum
GA660_RS06845	COG0693	protein deglycase activity
GA660_RS06855	COG1283	sodium-dependent phosphate transmembrane transporter activity
GA660_RS06865	COG1346	cytolysis
GA660_RS06875	COG0583	DNA-binding transcription factor activity
GA660_RS06900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GA660_RS06915	COG1629	transport
GA660_RS06925	COG1960	acyl-CoA dehydrogenase activity
GA660_RS06930	COG2207	Transcriptional regulator
GA660_RS06935	COG2814	Major facilitator Superfamily
GA660_RS06950	COG1294	oxidase, subunit
GA660_RS06960	COG1525	nuclease
GA660_RS07015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GA660_RS07020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GA660_RS07035	COG1113	amino acid transport
GA660_RS07045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GA660_RS07055	COG2814	Major facilitator Superfamily
GA660_RS07075	COG1132	(ABC) transporter
GA660_RS07090	COG0668	transmembrane transport
GA660_RS07095	COG3122	Protein conserved in bacteria
GA660_RS07115	COG0640	Transcriptional regulator
GA660_RS07120	COG2937	Belongs to the GPAT DAPAT family
GA660_RS07125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GA660_RS07130	COG1116	anion transmembrane transporter activity
GA660_RS07130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GA660_RS07140	COG2223	nitrite transmembrane transporter activity
GA660_RS07145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA660_RS07150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA660_RS07155	COG0243	molybdopterin cofactor binding
GA660_RS07165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GA660_RS07180	COG0521	Mo-molybdopterin cofactor biosynthetic process
GA660_RS07180	COG0315	cyclic pyranopterin monophosphate synthase activity
GA660_RS07185	COG0303	'Molybdopterin
GA660_RS07205	COG0583	DNA-binding transcription factor activity
GA660_RS07225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA660_RS07230	COG0183	Belongs to the thiolase family
GA660_RS07235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GA660_RS07240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GA660_RS07245	COG3135	benzoate transporter
GA660_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS07255	COG0633	Ferredoxin
GA660_RS07255	COG0543	2 iron, 2 sulfur cluster binding
GA660_RS07260	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GA660_RS07265	COG4638	Rieske (2fe-2S)
GA660_RS07275	COG4829	muconolactone delta-isomerase
GA660_RS07280	COG4948	Mandelate Racemase Muconate Lactonizing
GA660_RS07285	COG0583	DNA-binding transcription factor activity
GA660_RS07290	COG2814	Major facilitator Superfamily
GA660_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS07330	COG2223	nitrite transmembrane transporter activity
GA660_RS07340	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GA660_RS07345	COG2116	formate transmembrane transporter activity
GA660_RS07350	COG0515	serine threonine protein kinase
GA660_RS07380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA660_RS07415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GA660_RS07420	COG1309	transcriptional regulator
GA660_RS07425	COG1012	belongs to the aldehyde dehydrogenase family
GA660_RS07445	COG0745	RESPONSE REGULATOR receiver
GA660_RS07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GA660_RS07470	COG2885	chlorophyll binding
GA660_RS07480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GA660_RS07485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GA660_RS07490	COG0730	response to heat
GA660_RS07585	COG0596	Alpha beta hydrolase
GA660_RS07620	COG0511	ligase activity, forming carbon-carbon bonds
GA660_RS07625	COG0439	Biotin carboxylase
GA660_RS07640	COG2814	Major facilitator Superfamily
GA660_RS07675	COG1546	Belongs to the CinA family
GA660_RS07675	COG1058	Belongs to the CinA family
GA660_RS07685	COG0372	Belongs to the citrate synthase family
GA660_RS07720	COG0542	response to heat
GA660_RS07725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GA660_RS07745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GA660_RS07755	COG0569	domain protein
GA660_RS07760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GA660_RS07780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GA660_RS07790	COG1585	Membrane protein implicated in regulation of membrane protease activity
GA660_RS07805	COG1294	oxidase, subunit
GA660_RS07810	COG4890	Cyd operon protein YbgT
GA660_RS07845	COG1960	acyl-CoA dehydrogenase activity
GA660_RS07850	COG1960	acyl-CoA dehydrogenase activity
GA660_RS07860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GA660_RS07865	COG2207	Transcriptional regulator
GA660_RS07870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GA660_RS07875	COG0730	response to heat
GA660_RS07880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GA660_RS07910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GA660_RS07930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA660_RS07945	COG0575	Belongs to the CDS family
GA660_RS07950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GA660_RS07955	COG0233	cytoplasmic translational termination
GA660_RS07970	COG3852	Histidine kinase
GA660_RS07985	COG0583	DNA-binding transcription factor activity
GA660_RS07990	COG0024	Methionine aminopeptidase
GA660_RS08015	COG1253	flavin adenine dinucleotide binding
GA660_RS08040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GA660_RS08045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GA660_RS08060	COG2431	L-lysine efflux transmembrane transporter activity
GA660_RS08065	COG0284	orotidine-5'-phosphate decarboxylase activity
GA660_RS08075	COG0776	regulation of translation
GA660_RS08095	COG0590	tRNA wobble adenosine to inosine editing
GA660_RS08105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GA660_RS08140	COG0084	hydrolase, TatD family'
GA660_RS08160	COG1663	tetraacyldisaccharide 4'-kinase activity
GA660_RS08165	COG1132	(ABC) transporter
GA660_RS08175	COG0811	peptide transport
GA660_RS08180	COG1475	DNA binding
GA660_RS08185	COG1192	Involved in chromosome partitioning
GA660_RS08195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GA660_RS08200	COG3178	'Phosphotransferase
GA660_RS08210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GA660_RS08215	COG1923	regulation of RNA biosynthetic process
GA660_RS08225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GA660_RS08230	COG0802	atpase or kinase
GA660_RS08255	COG2707	UPF0756 membrane protein
GA660_RS08265	COG0583	DNA-binding transcription factor activity
GA660_RS08270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GA660_RS08300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GA660_RS08300	COG0519	Catalyzes the synthesis of GMP from XMP
GA660_RS08305	COG2353	YceI-like domain
GA660_RS08315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GA660_RS08320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GA660_RS08355	COG1254	Belongs to the acylphosphatase family
GA660_RS08360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GA660_RS08360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GA660_RS08365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GA660_RS08385	COG0318	PFAM AMP-dependent synthetase and ligase
GA660_RS08390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GA660_RS08395	COG3327	negative regulation of DNA-templated transcription, initiation
GA660_RS08400	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GA660_RS08405	COG0183	Belongs to the thiolase family
GA660_RS08410	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA660_RS08415	COG1024	Enoyl-CoA hydratase
GA660_RS08420	COG1024	Enoyl-CoA hydratase
GA660_RS08425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GA660_RS08430	COG2151	metal-sulfur cluster biosynthetic enzyme
GA660_RS08435	COG3396	Phenylacetate-CoA oxygenase
GA660_RS08440	COG3460	Phenylacetate-CoA oxygenase
GA660_RS08445	COG3396	Phenylacetate-CoA oxygenase
GA660_RS08450	COG1012	belongs to the aldehyde dehydrogenase family
GA660_RS08450	COG2030	dehydratase
GA660_RS08455	COG2814	Major facilitator Superfamily
GA660_RS08460	COG0783	Belongs to the Dps family
GA660_RS08475	COG2814	Major facilitator Superfamily
GA660_RS08480	COG2271	Major facilitator Superfamily
GA660_RS08485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GA660_RS08490	COG4948	Mandelate Racemase Muconate Lactonizing
GA660_RS08500	COG1309	transcriptional regulator
GA660_RS08505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GA660_RS08530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA660_RS08565	COG0133	tryptophan synthase activity
GA660_RS08590	COG0642	Histidine kinase
GA660_RS08605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GA660_RS08630	COG2816	NAD+ diphosphatase activity
GA660_RS08650	COG2351	hydroxyisourate hydrolase activity
GA660_RS08670	COG1136	(ABC) transporter
GA660_RS08680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA660_RS08695	COG1294	oxidase, subunit
GA660_RS08705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GA660_RS08775	COG0582	viral genome integration into host DNA
GA660_RS08785	COG0204	Acyl-transferase
GA660_RS08810	COG0012	GTP binding
GA660_RS08820	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GA660_RS08835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GA660_RS08840	COG0436	Aminotransferase
GA660_RS08845	COG0386	Belongs to the glutathione peroxidase family
GA660_RS08850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GA660_RS08855	COG0436	Aminotransferase
GA660_RS08860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GA660_RS08860	COG2755	lipolytic protein G-D-S-L family
GA660_RS08900	COG0515	serine threonine protein kinase
GA660_RS08900	COG2815	serine threonine protein kinase
GA660_RS08940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GA660_RS08945	COG1610	YqeY-like protein
GA660_RS08960	COG4783	chaperone-mediated protein folding
GA660_RS09025	COG0513	Belongs to the DEAD box helicase family
GA660_RS09045	COG2363	Small membrane protein
GA660_RS09065	COG0659	secondary active sulfate transmembrane transporter activity
GA660_RS09075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GA660_RS09095	COG0318	PFAM AMP-dependent synthetase and ligase
GA660_RS09100	COG1309	transcriptional regulator
GA660_RS09105	COG1960	acyl-CoA dehydrogenase activity
GA660_RS09110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GA660_RS09115	COG1024	Enoyl-CoA hydratase
GA660_RS09135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GA660_RS09150	COG0540	Belongs to the ATCase OTCase family
GA660_RS09175	COG1765	OsmC-like protein
GA660_RS09185	COG0667	Aldo Keto reductase
GA660_RS09200	COG0501	Belongs to the peptidase M48B family
GA660_RS09205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GA660_RS09220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GA660_RS09230	COG0527	aspartate kinase activity
GA660_RS09240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GA660_RS09250	COG1215	transferase activity, transferring glycosyl groups
GA660_RS09260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GA660_RS09265	COG2252	PERMEase
GA660_RS09295	COG0714	Associated with various cellular activities
GA660_RS09300	COG2879	small protein
GA660_RS09305	COG1966	Carbon starvation protein
GA660_RS09310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GA660_RS09315	COG1509	lysine 2,3-aminomutase activity
GA660_RS09350	COG1067	ATP-dependent peptidase activity
GA660_RS09355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GA660_RS09360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GA660_RS09365	COG0583	DNA-binding transcription factor activity
GA660_RS09375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GA660_RS09390	COG1686	Belongs to the peptidase S11 family
GA660_RS09395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GA660_RS09440	COG0616	signal peptide processing
GA660_RS09445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GA660_RS09455	COG0573	inorganic phosphate transmembrane transporter activity
GA660_RS09465	COG0076	glutamate decarboxylase activity
GA660_RS09470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GA660_RS09480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GA660_RS09490	COG2814	Major facilitator Superfamily
GA660_RS09495	COG1733	regulation of RNA biosynthetic process
GA660_RS09500	COG0702	epimerase
GA660_RS09530	COG0556	nucleotide-excision repair
GA660_RS09570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GA660_RS09575	COG1381	Involved in DNA repair and RecF pathway recombination
GA660_RS09585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GA660_RS09590	COG0571	ribonuclease III activity
GA660_RS09600	COG0681	Belongs to the peptidase S26 family
GA660_RS09615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GA660_RS09625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GA660_RS09640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GA660_RS09650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GA660_RS09665	COG4208	sulfate ABC transporter
GA660_RS09670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GA660_RS09675	COG0583	DNA-binding transcription factor activity
GA660_RS09695	COG0602	queuosine metabolic process
GA660_RS09700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GA660_RS09710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GA660_RS09715	COG2353	YceI-like domain
GA660_RS09720	COG1056	cytidyltransferase-related domain
GA660_RS09720	COG1051	belongs to the nudix hydrolase family
GA660_RS09725	COG1024	Enoyl-CoA hydratase
GA660_RS09730	COG0778	Nitroreductase
GA660_RS09745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GA660_RS09745	COG0047	phosphoribosylformylglycinamidine synthase activity
GA660_RS09765	COG2255	four-way junction helicase activity
GA660_RS09775	COG0824	Thioesterase
GA660_RS09795	COG0823	Involved in the tonB-independent uptake of proteins
GA660_RS09815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GA660_RS09850	COG0628	permease
GA660_RS09855	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GA660_RS09860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GA660_RS09880	COG2333	competence protein COMEC
GA660_RS09880	COG0658	competence protein
GA660_RS09885	COG1136	(ABC) transporter
GA660_RS09890	COG4591	ABC-type transport system involved in lipoprotein release permease component
GA660_RS09905	COG1671	Belongs to the UPF0178 family
GA660_RS09945	COG1280	lysine exporter protein (LysE YggA)
GA660_RS09950	COG1522	sequence-specific DNA binding
GA660_RS09960	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GA660_RS09975	COG0019	diaminopimelate decarboxylase activity
GA660_RS09985	COG1113	amino acid transport
GA660_RS09990	COG1115	amino acid carrier protein
GA660_RS10010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GA660_RS10015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GA660_RS10050	COG0583	DNA-binding transcription factor activity
GA660_RS10060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GA660_RS10075	COG0512	Glutamine amidotransferase of anthranilate synthase
GA660_RS10105	COG3706	GGDEF domain
GA660_RS10120	COG3739	integral membrane protein
GA660_RS10125	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GA660_RS10135	COG1741	Belongs to the pirin family
GA660_RS10140	COG3842	ATPase activity
GA660_RS10145	COG1840	ABC-type Fe3 transport system, periplasmic component
GA660_RS10165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GA660_RS10170	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GA660_RS10180	COG0037	tRNA processing
GA660_RS10185	COG1196	nuclear chromosome segregation
GA660_RS10185	COG0741	lytic transglycosylase activity
GA660_RS10185	COG0739	heme binding
GA660_RS10190	COG0501	Belongs to the peptidase M48B family
GA660_RS10200	COG2239	Acts as a magnesium transporter
GA660_RS10245	COG1597	lipid kinase activity
GA660_RS10245	COG1803	Methylglyoxal synthase
GA660_RS10265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GA660_RS10300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GA660_RS10310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GA660_RS10320	COG1534	Rna-binding protein
GA660_RS10335	COG0505	Belongs to the CarA family
GA660_RS10350	COG0415	Belongs to the DNA photolyase family
GA660_RS10355	COG0110	maltose O-acetyltransferase activity
GA660_RS10360	COG0589	response to stress
GA660_RS10370	COG2321	neutral zinc metallopeptidase
GA660_RS10375	COG2354	Protein conserved in bacteria
GA660_RS10390	COG2268	Band 7 protein
GA660_RS10400	COG1215	transferase activity, transferring glycosyl groups
GA660_RS10405	COG1649	PFAM Uncharacterised BCR, COG1649
GA660_RS10405	COG0726	polysaccharide deacetylase
GA660_RS10415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GA660_RS10425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GA660_RS10440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GA660_RS10445	COG1053	succinate dehydrogenase
GA660_RS10450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GA660_RS10455	COG2009	succinate dehydrogenase
GA660_RS10465	COG2072	flavoprotein involved in K transport
GA660_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS10480	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GA660_RS10485	COG0714	Associated with various cellular activities
GA660_RS10495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GA660_RS10495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GA660_RS10525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GA660_RS10535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GA660_RS10550	COG0564	pseudouridine synthase activity
GA660_RS10560	COG0358	DNA primase activity
GA660_RS10575	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GA660_RS10605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GA660_RS10645	COG0586	Pfam SNARE associated Golgi protein
GA660_RS10670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GA660_RS10680	COG0321	lipoyl(octanoyl) transferase activity
GA660_RS10695	COG0531	amino acid
GA660_RS10700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GA660_RS10705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GA660_RS10705	COG1648	precorrin-2 dehydrogenase activity
GA660_RS10710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GA660_RS10720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GA660_RS10745	COG0671	phosphoesterase, PA-phosphatase related
GA660_RS10750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA660_RS10760	COG1538	Outer membrane efflux protein
GA660_RS10765	COG0393	Putative heavy-metal-binding
GA660_RS10770	COG0393	Putative heavy-metal-binding
GA660_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS10785	COG0525	valine-tRNA ligase activity
GA660_RS10795	COG2852	Protein conserved in bacteria
GA660_RS10815	COG1943	Transposase
GA660_RS10820	COG2323	membrane
GA660_RS10835	COG0765	amino acid transport
GA660_RS10840	COG0765	amino acid transport
GA660_RS10845	COG1126	abc transporter atp-binding protein
GA660_RS10865	COG1752	Esterase of the alpha-beta hydrolase superfamily
GA660_RS10880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GA660_RS10885	COG2205	protein histidine kinase activity
GA660_RS10890	COG0745	RESPONSE REGULATOR receiver
GA660_RS10905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GA660_RS10910	COG1652	LysM domain
GA660_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS10930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GA660_RS10935	COG1399	metal-binding, possibly nucleic acid-binding protein
GA660_RS10940	COG3101	peptidyl-lysine hydroxylation
GA660_RS10945	COG0009	L-threonylcarbamoyladenylate synthase
GA660_RS10955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GA660_RS10960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GA660_RS10975	COG4106	trans-aconitate 2-methyltransferase activity
GA660_RS10990	COG2226	methyltransferase
GA660_RS10990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA660_RS10990	COG0596	Alpha beta hydrolase
GA660_RS10995	COG2193	ferroxidase activity
GA660_RS11000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GA660_RS11005	COG3115	cell septum assembly
GA660_RS11010	COG1196	nuclear chromosome segregation
GA660_RS11020	COG0730	response to heat
GA660_RS11040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GA660_RS11090	COG0628	permease
GA660_RS11100	COG2824	Alkylphosphonate utilization operon protein PhnA
GA660_RS11105	COG3189	MarR family transcriptional regulator
GA660_RS11120	COG0564	pseudouridine synthase activity
GA660_RS11150	COG0354	folic acid binding
GA660_RS11180	COG0363	glucosamine-6-phosphate deaminase activity
GA660_RS11190	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GA660_RS11195	COG1877	trehalose-phosphatase activity
GA660_RS11205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GA660_RS11210	COG1970	mechanosensitive ion channel activity
GA660_RS11220	COG2233	PERMEase
GA660_RS11230	COG0833	amino acid
GA660_RS11240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GA660_RS11240	COG2885	chlorophyll binding
GA660_RS11250	COG0183	Belongs to the thiolase family
GA660_RS11265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA660_RS11275	COG2207	Transcriptional regulator
GA660_RS11280	COG0183	Belongs to the thiolase family
GA660_RS11285	COG1024	Enoyl-CoA hydratase
GA660_RS11285	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA660_RS11305	COG1272	protein, Hemolysin III
GA660_RS11310	COG0477	Major facilitator Superfamily
GA660_RS11320	COG1408	metallophosphoesterase
GA660_RS11325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GA660_RS11335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GA660_RS11365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GA660_RS11370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GA660_RS11375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GA660_RS11385	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GA660_RS11390	COG0625	glutathione transferase activity
GA660_RS11395	COG2969	positive regulation of protein catabolic process
GA660_RS11450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GA660_RS11495	COG0037	tRNA processing
GA660_RS11505	COG0248	Ppx GppA phosphatase
GA660_RS11530	COG0072	phenylalanine-tRNA ligase activity
GA660_RS11550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GA660_RS11565	COG1238	metal cluster binding
GA660_RS11570	COG0625	glutathione transferase activity
GA660_RS11585	COG0318	PFAM AMP-dependent synthetase and ligase
GA660_RS11590	COG3028	Belongs to the UPF0307 family
GA660_RS11600	COG1660	Displays ATPase and GTPase activities
GA660_RS11615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GA660_RS11620	COG0617	tRNA 3'-terminal CCA addition
GA660_RS11625	COG1555	photosystem II stabilization
GA660_RS11630	COG3956	TIGRFAM MazG family protein
GA660_RS11645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA660_RS11655	COG0124	histidyl-tRNA synthetase
GA660_RS11685	COG2975	iron-sulfur cluster assembly
GA660_RS11725	COG0440	acetolactate synthase activity
GA660_RS11730	COG0028	Belongs to the TPP enzyme family
GA660_RS11755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA660_RS11760	COG1136	(ABC) transporter
GA660_RS11760	COG0577	efflux transmembrane transporter activity
GA660_RS11800	COG3501	Rhs element vgr protein
GA660_RS11815	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GA660_RS11820	COG1162	GTPase activity
GA660_RS11830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GA660_RS11840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GA660_RS11850	COG3781	membrane
GA660_RS11855	COG0613	PHP domain protein
GA660_RS11865	COG2350	Protein conserved in bacteria
GA660_RS11885	COG1666	GTP binding
GA660_RS11895	COG1607	acyl-coa hydrolase
GA660_RS11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GA660_RS11910	COG3453	Protein conserved in bacteria
GA660_RS11955	COG1183	phosphatidylcholine synthase activity
GA660_RS11960	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GA660_RS12000	COG0739	heme binding
GA660_RS12000	COG1196	nuclear chromosome segregation
GA660_RS12000	COG0741	lytic transglycosylase activity
GA660_RS12005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GA660_RS12010	COG1702	phosphate starvation-inducible protein PhoH
GA660_RS12060	COG1295	ribonuclease BN
GA660_RS12090	COG0788	formyltetrahydrofolate deformylase activity
GA660_RS12105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GA660_RS12110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GA660_RS12115	COG4651	solute:proton antiporter activity
GA660_RS12115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GA660_RS12130	COG0724	RNA recognition motif
GA660_RS12135	COG0210	DNA helicase
GA660_RS12145	COG1929	Belongs to the glycerate kinase type-1 family
GA660_RS12185	COG1560	Kdo2-lipid A biosynthetic process
GA660_RS12240	COG0473	3-isopropylmalate dehydrogenase activity
GA660_RS12255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GA660_RS12285	COG0494	nUDIX hydrolase
GA660_RS12305	COG1960	acyl-CoA dehydrogenase activity
GA660_RS12315	COG0753	catalase activity
GA660_RS12330	COG0446	pyridine nucleotide-disulphide oxidoreductase
GA660_RS12335	COG3384	dioxygenase
GA660_RS12340	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS12355	COG4638	Rieske (2fe-2S)
GA660_RS12360	COG0583	DNA-binding transcription factor activity
GA660_RS12385	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GA660_RS12390	COG3971	2-oxopent-4-enoate hydratase activity
GA660_RS12395	COG0546	phosphoglycolate phosphatase activity
GA660_RS12405	COG1530	ribonuclease E activity
GA660_RS12435	COG1983	PspC domain protein
GA660_RS12450	COG0751	glycine-tRNA ligase activity
GA660_RS12480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GA660_RS12505	COG0493	'glutamate synthase
GA660_RS12505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GA660_RS12515	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GA660_RS12525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GA660_RS12540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GA660_RS12550	COG0644	oxidoreductase
GA660_RS12550	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GA660_RS12590	COG3501	Rhs element vgr protein
GA660_RS12595	COG0425	Belongs to the sulfur carrier protein TusA family
GA660_RS12600	COG4535	Mg2 and Co2 transporter CorC
GA660_RS12605	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GA660_RS12615	COG2165	general secretion pathway protein
GA660_RS12630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GA660_RS12640	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GA660_RS12650	COG0789	Transcriptional regulator
GA660_RS12655	COG2841	Protein conserved in bacteria
GA660_RS12670	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GA660_RS12675	COG0675	Transposase, IS605 OrfB family
GA660_RS12680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GA660_RS12685	COG1074	ATP-dependent DNA helicase activity
GA660_RS12690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GA660_RS12720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GA660_RS12730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GA660_RS12745	COG2111	Na H antiporter
GA660_RS12745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GA660_RS12750	COG1006	Multisubunit Na H antiporter MnhC subunit
GA660_RS12755	COG0651	ATP synthesis coupled electron transport
GA660_RS12765	COG2212	antiporter activity
GA660_RS12775	COG3385	transposase activity
GA660_RS12780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GA660_RS12790	COG0195	Participates in both transcription termination and antitermination
GA660_RS12795	COG0779	Required for maturation of 30S ribosomal subunits
GA660_RS12845	COG0237	dephospho-CoA kinase activity
GA660_RS12855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GA660_RS12860	COG3123	guanosine phosphorylase activity
GA660_RS12865	COG0497	DNA recombination
GA660_RS12875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GA660_RS12890	COG1132	(ABC) transporter
GA660_RS12895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GA660_RS12925	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA660_RS12925	COG1024	Enoyl-CoA hydratase
GA660_RS12935	COG2233	PERMEase
GA660_RS12945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GA660_RS12970	COG0326	Molecular chaperone. Has ATPase activity
GA660_RS12985	COG2056	Na+-H+ antiporter family
GA660_RS13005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GA660_RS13010	COG0085	RNA polymerase activity
GA660_RS13025	COG0081	regulation of translation
GA660_RS13080	COG0546	phosphoglycolate phosphatase activity
GA660_RS13085	COG1716	ATPase activity
GA660_RS13110	COG0824	Thioesterase
GA660_RS13130	COG0181	hydroxymethylbilane synthase activity
GA660_RS13140	COG3275	phosphorelay sensor kinase activity
GA660_RS13175	COG0494	nUDIX hydrolase
GA660_RS13180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GA660_RS13185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GA660_RS13190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GA660_RS13200	COG0772	Belongs to the SEDS family
GA660_RS13225	COG4974	Belongs to the 'phage' integrase family
GA660_RS13240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GA660_RS13250	COG2197	response regulator
GA660_RS13265	COG0793	Belongs to the peptidase S41A family
GA660_RS13270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GA660_RS13275	COG0795	lipopolysaccharide-transporting ATPase activity
GA660_RS13280	COG0795	lipopolysaccharide-transporting ATPase activity
GA660_RS13305	COG3385	transposase activity
GA660_RS13310	COG0586	Pfam SNARE associated Golgi protein
GA660_RS13325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GA660_RS13325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GA660_RS13335	COG0004	ammonium transporteR
GA660_RS13340	COG0347	Belongs to the P(II) protein family
GA660_RS13350	COG0606	chelatase, subunit chli
GA660_RS13365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GA660_RS13380	COG0318	PFAM AMP-dependent synthetase and ligase
GA660_RS13390	COG0477	Major facilitator Superfamily
GA660_RS13395	COG2860	membrane
GA660_RS13405	COG1253	flavin adenine dinucleotide binding
GA660_RS13425	COG2814	Major facilitator Superfamily
GA660_RS13440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GA660_RS13460	COG2814	Major facilitator Superfamily
GA660_RS13510	COG0758	DNA mediated transformation
GA660_RS13520	COG0697	spore germination
GA660_RS13525	COG0386	Belongs to the glutathione peroxidase family
GA660_RS13550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GA660_RS13560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GA660_RS13600	COG1121	(ABC) transporter
GA660_RS13605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GA660_RS13610	COG1280	lysine exporter protein (LysE YggA)
GA660_RS13615	COG2837	iron assimilation
GA660_RS13635	COG3179	chitinase
GA660_RS13640	COG3501	Rhs element vgr protein
GA660_RS13645	COG0281	malic enzyme
GA660_RS13680	COG3706	GGDEF domain
GA660_RS13680	COG0745	RESPONSE REGULATOR receiver
GA660_RS13685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GA660_RS13685	COG0519	Catalyzes the synthesis of GMP from XMP
GA660_RS13690	COG2259	Doxx family
GA660_RS13695	COG0586	Pfam SNARE associated Golgi protein
GA660_RS13710	COG1192	Involved in chromosome partitioning
GA660_RS13720	COG0271	Belongs to the BolA IbaG family
GA660_RS13750	COG3756	Protein conserved in bacteria
GA660_RS13770	COG1028	Short-chain dehydrogenase reductase Sdr
GA660_RS13785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GA660_RS13815	COG4974	Belongs to the 'phage' integrase family
GA660_RS13830	COG3316	Transposase and inactivated derivatives
GA660_RS13850	COG2801	Transposase and inactivated derivatives
GA660_RS13870	COG3077	Addiction module antitoxin, RelB DinJ family
GA660_RS13895	COG3316	Transposase and inactivated derivatives
GA660_RS13945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GA660_RS13950	COG3316	Transposase and inactivated derivatives
GA660_RS13955	COG1660	Displays ATPase and GTPase activities
GA660_RS13985	COG5002	protein histidine kinase activity
GA660_RS13995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GA660_RS14005	COG3316	Transposase and inactivated derivatives
GA660_RS14015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GA660_RS14030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GA660_RS14035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GA660_RS14050	COG1570	exodeoxyribonuclease VII activity
GA660_RS14115	COG4628	conserved protein (DUF2132)
GA660_RS14125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GA660_RS14140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GA660_RS14150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GA660_RS14185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GA660_RS14200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GA660_RS14210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GA660_RS14220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GA660_RS14225	COG0438	transferase activity, transferring glycosyl groups
GA660_RS14245	COG0438	transferase activity, transferring glycosyl groups
GA660_RS14260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GA660_RS14315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA660_RS14320	COG1309	transcriptional regulator
GA660_RS14335	COG1196	nuclear chromosome segregation
GA660_RS14335	COG0741	lytic transglycosylase activity
GA660_RS14335	COG0739	heme binding
GA660_RS14350	COG1196	nuclear chromosome segregation
GA660_RS14350	COG0741	lytic transglycosylase activity
GA660_RS14350	COG0739	heme binding
GA660_RS14405	COG1192	Involved in chromosome partitioning
GA660_RS14470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GA660_RS14500	COG2826	transposase and inactivated derivatives, IS30 family
GA660_RS14520	COG0673	inositol 2-dehydrogenase activity
GA660_RS14540	COG1525	nuclease