locus-tag	class	description
GA693_RS00075	COG4115	mRNA cleavage
GA693_RS00125	COG1192	Involved in chromosome partitioning
GA693_RS00230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GA693_RS00295	COG1192	Involved in chromosome partitioning
GA693_RS00350	COG1196	nuclear chromosome segregation
GA693_RS00350	COG0739	heme binding
GA693_RS00350	COG0741	lytic transglycosylase activity
GA693_RS00365	COG0739	heme binding
GA693_RS00365	COG0741	lytic transglycosylase activity
GA693_RS00365	COG1196	nuclear chromosome segregation
GA693_RS00390	COG1525	nuclease
GA693_RS00410	COG0673	inositol 2-dehydrogenase activity
GA693_RS00435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GA693_RS00440	COG1183	phosphatidylcholine synthase activity
GA693_RS00485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GA693_RS00485	COG3453	Protein conserved in bacteria
GA693_RS00500	COG1607	acyl-coa hydrolase
GA693_RS00510	COG1666	GTP binding
GA693_RS00530	COG2350	Protein conserved in bacteria
GA693_RS00540	COG0613	PHP domain protein
GA693_RS00545	COG3781	membrane
GA693_RS00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GA693_RS00565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GA693_RS00575	COG1162	GTPase activity
GA693_RS00580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GA693_RS00595	COG3501	Rhs element vgr protein
GA693_RS00635	COG1136	(ABC) transporter
GA693_RS00635	COG0577	efflux transmembrane transporter activity
GA693_RS00640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA693_RS00665	COG0028	Belongs to the TPP enzyme family
GA693_RS00670	COG0440	acetolactate synthase activity
GA693_RS00710	COG2975	iron-sulfur cluster assembly
GA693_RS00740	COG0124	histidyl-tRNA synthetase
GA693_RS00750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA693_RS00765	COG3956	TIGRFAM MazG family protein
GA693_RS00770	COG1555	photosystem II stabilization
GA693_RS00775	COG0617	tRNA 3'-terminal CCA addition
GA693_RS00780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GA693_RS00795	COG1660	Displays ATPase and GTPase activities
GA693_RS00805	COG3028	Belongs to the UPF0307 family
GA693_RS00810	COG0318	PFAM AMP-dependent synthetase and ligase
GA693_RS00825	COG0625	glutathione transferase activity
GA693_RS00830	COG1238	metal cluster binding
GA693_RS00845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GA693_RS00865	COG0072	phenylalanine-tRNA ligase activity
GA693_RS00890	COG0248	Ppx GppA phosphatase
GA693_RS00900	COG0037	tRNA processing
GA693_RS00945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GA693_RS01000	COG2969	positive regulation of protein catabolic process
GA693_RS01005	COG0625	glutathione transferase activity
GA693_RS01010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GA693_RS01020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GA693_RS01025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GA693_RS01030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GA693_RS01060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GA693_RS01070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GA693_RS01075	COG1408	metallophosphoesterase
GA693_RS01085	COG0477	Major facilitator Superfamily
GA693_RS01090	COG1272	protein, Hemolysin III
GA693_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA693_RS01110	COG1024	Enoyl-CoA hydratase
GA693_RS01115	COG0183	Belongs to the thiolase family
GA693_RS01120	COG2207	Transcriptional regulator
GA693_RS01130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA693_RS01145	COG0183	Belongs to the thiolase family
GA693_RS01155	COG2885	chlorophyll binding
GA693_RS01155	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GA693_RS01165	COG0833	amino acid
GA693_RS01175	COG2233	PERMEase
GA693_RS01185	COG1970	mechanosensitive ion channel activity
GA693_RS01190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GA693_RS01200	COG1877	trehalose-phosphatase activity
GA693_RS01205	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GA693_RS01215	COG0363	glucosamine-6-phosphate deaminase activity
GA693_RS01245	COG0354	folic acid binding
GA693_RS01275	COG0564	pseudouridine synthase activity
GA693_RS01290	COG3189	MarR family transcriptional regulator
GA693_RS01295	COG2824	Alkylphosphonate utilization operon protein PhnA
GA693_RS01305	COG0628	permease
GA693_RS01355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GA693_RS01375	COG0730	response to heat
GA693_RS01385	COG1196	nuclear chromosome segregation
GA693_RS01390	COG3115	cell septum assembly
GA693_RS01395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GA693_RS01400	COG2193	ferroxidase activity
GA693_RS01405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA693_RS01405	COG0596	Alpha beta hydrolase
GA693_RS01405	COG2226	methyltransferase
GA693_RS01420	COG4106	trans-aconitate 2-methyltransferase activity
GA693_RS01435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GA693_RS01440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GA693_RS01450	COG0009	L-threonylcarbamoyladenylate synthase
GA693_RS01455	COG3101	peptidyl-lysine hydroxylation
GA693_RS01460	COG1399	metal-binding, possibly nucleic acid-binding protein
GA693_RS01465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GA693_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS01485	COG1652	LysM domain
GA693_RS01490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GA693_RS01505	COG0745	RESPONSE REGULATOR receiver
GA693_RS01510	COG2205	protein histidine kinase activity
GA693_RS01515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GA693_RS01530	COG1752	Esterase of the alpha-beta hydrolase superfamily
GA693_RS01550	COG1126	abc transporter atp-binding protein
GA693_RS01555	COG0765	amino acid transport
GA693_RS01560	COG0765	amino acid transport
GA693_RS01575	COG2323	membrane
GA693_RS01580	COG1943	Transposase
GA693_RS01600	COG2852	Protein conserved in bacteria
GA693_RS01610	COG0525	valine-tRNA ligase activity
GA693_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS01625	COG0393	Putative heavy-metal-binding
GA693_RS01630	COG0393	Putative heavy-metal-binding
GA693_RS01635	COG1538	Outer membrane efflux protein
GA693_RS01645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA693_RS01650	COG0671	phosphoesterase, PA-phosphatase related
GA693_RS01675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GA693_RS01685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GA693_RS01690	COG1648	precorrin-2 dehydrogenase activity
GA693_RS01690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GA693_RS01695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GA693_RS01700	COG0531	amino acid
GA693_RS01715	COG0321	lipoyl(octanoyl) transferase activity
GA693_RS01725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GA693_RS01750	COG0586	Pfam SNARE associated Golgi protein
GA693_RS01790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GA693_RS01820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GA693_RS01835	COG0358	DNA primase activity
GA693_RS01845	COG0564	pseudouridine synthase activity
GA693_RS01860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GA693_RS01870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GA693_RS01900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GA693_RS01900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GA693_RS01910	COG0714	Associated with various cellular activities
GA693_RS01915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GA693_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS01930	COG2072	flavoprotein involved in K transport
GA693_RS01940	COG2009	succinate dehydrogenase
GA693_RS01945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GA693_RS01950	COG1053	succinate dehydrogenase
GA693_RS01955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GA693_RS01970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GA693_RS01980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GA693_RS01990	COG0726	polysaccharide deacetylase
GA693_RS01990	COG1649	PFAM Uncharacterised BCR, COG1649
GA693_RS01995	COG1215	transferase activity, transferring glycosyl groups
GA693_RS02005	COG2268	Band 7 protein
GA693_RS02020	COG2354	Protein conserved in bacteria
GA693_RS02025	COG2321	neutral zinc metallopeptidase
GA693_RS02035	COG0589	response to stress
GA693_RS02040	COG0110	maltose O-acetyltransferase activity
GA693_RS02045	COG0415	Belongs to the DNA photolyase family
GA693_RS02060	COG0505	Belongs to the CarA family
GA693_RS02075	COG1534	Rna-binding protein
GA693_RS02085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GA693_RS02095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GA693_RS02130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GA693_RS02150	COG1803	Methylglyoxal synthase
GA693_RS02150	COG1597	lipid kinase activity
GA693_RS02195	COG2239	Acts as a magnesium transporter
GA693_RS02205	COG0501	Belongs to the peptidase M48B family
GA693_RS02210	COG0741	lytic transglycosylase activity
GA693_RS02210	COG1196	nuclear chromosome segregation
GA693_RS02210	COG0739	heme binding
GA693_RS02215	COG0037	tRNA processing
GA693_RS02225	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GA693_RS02230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GA693_RS02250	COG1840	ABC-type Fe3 transport system, periplasmic component
GA693_RS02255	COG3842	ATPase activity
GA693_RS02260	COG1741	Belongs to the pirin family
GA693_RS02270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GA693_RS02275	COG3739	integral membrane protein
GA693_RS02290	COG3706	GGDEF domain
GA693_RS02320	COG0512	Glutamine amidotransferase of anthranilate synthase
GA693_RS02335	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GA693_RS02345	COG0583	DNA-binding transcription factor activity
GA693_RS02380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GA693_RS02385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GA693_RS02405	COG1115	amino acid carrier protein
GA693_RS02410	COG1113	amino acid transport
GA693_RS02420	COG0019	diaminopimelate decarboxylase activity
GA693_RS02435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GA693_RS02445	COG1522	sequence-specific DNA binding
GA693_RS02450	COG1280	lysine exporter protein (LysE YggA)
GA693_RS02490	COG1671	Belongs to the UPF0178 family
GA693_RS02505	COG4591	ABC-type transport system involved in lipoprotein release permease component
GA693_RS02510	COG1136	(ABC) transporter
GA693_RS02515	COG0658	competence protein
GA693_RS02515	COG2333	competence protein COMEC
GA693_RS02535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GA693_RS02540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GA693_RS02545	COG0628	permease
GA693_RS02580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GA693_RS02600	COG0823	Involved in the tonB-independent uptake of proteins
GA693_RS02620	COG0824	Thioesterase
GA693_RS02630	COG2255	four-way junction helicase activity
GA693_RS02650	COG0047	phosphoribosylformylglycinamidine synthase activity
GA693_RS02650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GA693_RS02665	COG0778	Nitroreductase
GA693_RS02670	COG1024	Enoyl-CoA hydratase
GA693_RS02675	COG1051	belongs to the nudix hydrolase family
GA693_RS02675	COG1056	cytidyltransferase-related domain
GA693_RS02680	COG2353	YceI-like domain
GA693_RS02685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GA693_RS02695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GA693_RS02700	COG0602	queuosine metabolic process
GA693_RS02720	COG0583	DNA-binding transcription factor activity
GA693_RS02725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GA693_RS02730	COG4208	sulfate ABC transporter
GA693_RS02745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GA693_RS02755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GA693_RS02770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GA693_RS02780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GA693_RS02795	COG0681	Belongs to the peptidase S26 family
GA693_RS02805	COG0571	ribonuclease III activity
GA693_RS02810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GA693_RS02820	COG1381	Involved in DNA repair and RecF pathway recombination
GA693_RS02825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GA693_RS02865	COG0556	nucleotide-excision repair
GA693_RS02895	COG0702	epimerase
GA693_RS02900	COG1733	regulation of RNA biosynthetic process
GA693_RS02905	COG2814	Major facilitator Superfamily
GA693_RS02915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GA693_RS02925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GA693_RS02930	COG0076	glutamate decarboxylase activity
GA693_RS02940	COG0573	inorganic phosphate transmembrane transporter activity
GA693_RS02950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GA693_RS02955	COG0616	signal peptide processing
GA693_RS03000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GA693_RS03005	COG1686	Belongs to the peptidase S11 family
GA693_RS03020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GA693_RS03030	COG0583	DNA-binding transcription factor activity
GA693_RS03035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GA693_RS03040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GA693_RS03045	COG1067	ATP-dependent peptidase activity
GA693_RS03080	COG1509	lysine 2,3-aminomutase activity
GA693_RS03085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GA693_RS03090	COG1966	Carbon starvation protein
GA693_RS03095	COG2879	small protein
GA693_RS03100	COG0714	Associated with various cellular activities
GA693_RS03130	COG2252	PERMEase
GA693_RS03135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GA693_RS03145	COG1215	transferase activity, transferring glycosyl groups
GA693_RS03155	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GA693_RS03165	COG0527	aspartate kinase activity
GA693_RS03175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GA693_RS03190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GA693_RS03195	COG0501	Belongs to the peptidase M48B family
GA693_RS03210	COG0667	Aldo Keto reductase
GA693_RS03220	COG1765	OsmC-like protein
GA693_RS03245	COG0540	Belongs to the ATCase OTCase family
GA693_RS03260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GA693_RS03280	COG1024	Enoyl-CoA hydratase
GA693_RS03285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GA693_RS03290	COG1960	acyl-CoA dehydrogenase activity
GA693_RS03295	COG1309	transcriptional regulator
GA693_RS03300	COG0318	PFAM AMP-dependent synthetase and ligase
GA693_RS03320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GA693_RS03330	COG0659	secondary active sulfate transmembrane transporter activity
GA693_RS03350	COG2363	Small membrane protein
GA693_RS03370	COG0513	Belongs to the DEAD box helicase family
GA693_RS03435	COG4783	chaperone-mediated protein folding
GA693_RS03450	COG1610	YqeY-like protein
GA693_RS03455	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GA693_RS03495	COG2815	serine threonine protein kinase
GA693_RS03495	COG0515	serine threonine protein kinase
GA693_RS03535	COG2755	lipolytic protein G-D-S-L family
GA693_RS03535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GA693_RS03540	COG0436	Aminotransferase
GA693_RS03545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GA693_RS03550	COG0386	Belongs to the glutathione peroxidase family
GA693_RS03555	COG0436	Aminotransferase
GA693_RS03560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GA693_RS03575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GA693_RS03585	COG0012	GTP binding
GA693_RS03610	COG0204	Acyl-transferase
GA693_RS03620	COG0582	viral genome integration into host DNA
GA693_RS03690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GA693_RS03700	COG1294	oxidase, subunit
GA693_RS03715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA693_RS03725	COG1136	(ABC) transporter
GA693_RS03745	COG2351	hydroxyisourate hydrolase activity
GA693_RS03765	COG2816	NAD+ diphosphatase activity
GA693_RS03790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GA693_RS03805	COG0642	Histidine kinase
GA693_RS03830	COG0133	tryptophan synthase activity
GA693_RS03865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA693_RS03890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GA693_RS03895	COG1309	transcriptional regulator
GA693_RS03905	COG4948	Mandelate Racemase Muconate Lactonizing
GA693_RS03910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GA693_RS03915	COG2271	Major facilitator Superfamily
GA693_RS03920	COG2814	Major facilitator Superfamily
GA693_RS03935	COG0783	Belongs to the Dps family
GA693_RS03940	COG2814	Major facilitator Superfamily
GA693_RS03945	COG1012	belongs to the aldehyde dehydrogenase family
GA693_RS03945	COG2030	dehydratase
GA693_RS03950	COG3396	Phenylacetate-CoA oxygenase
GA693_RS03955	COG3460	Phenylacetate-CoA oxygenase
GA693_RS03960	COG3396	Phenylacetate-CoA oxygenase
GA693_RS03965	COG2151	metal-sulfur cluster biosynthetic enzyme
GA693_RS03970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GA693_RS03975	COG1024	Enoyl-CoA hydratase
GA693_RS03980	COG1024	Enoyl-CoA hydratase
GA693_RS03985	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA693_RS03990	COG0183	Belongs to the thiolase family
GA693_RS03995	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GA693_RS04000	COG3327	negative regulation of DNA-templated transcription, initiation
GA693_RS04005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GA693_RS04010	COG0318	PFAM AMP-dependent synthetase and ligase
GA693_RS04030	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GA693_RS04035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GA693_RS04035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GA693_RS04040	COG1254	Belongs to the acylphosphatase family
GA693_RS04075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GA693_RS04080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GA693_RS04090	COG2353	YceI-like domain
GA693_RS04095	COG0519	Catalyzes the synthesis of GMP from XMP
GA693_RS04095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GA693_RS04125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GA693_RS04130	COG0583	DNA-binding transcription factor activity
GA693_RS04140	COG2707	UPF0756 membrane protein
GA693_RS04165	COG0802	atpase or kinase
GA693_RS04170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GA693_RS04180	COG1923	regulation of RNA biosynthetic process
GA693_RS04185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GA693_RS04195	COG3178	'Phosphotransferase
GA693_RS04200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GA693_RS04210	COG1192	Involved in chromosome partitioning
GA693_RS04215	COG1475	DNA binding
GA693_RS04220	COG0811	peptide transport
GA693_RS04230	COG1132	(ABC) transporter
GA693_RS04235	COG1663	tetraacyldisaccharide 4'-kinase activity
GA693_RS04255	COG0084	hydrolase, TatD family'
GA693_RS04290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GA693_RS04300	COG0590	tRNA wobble adenosine to inosine editing
GA693_RS04320	COG0776	regulation of translation
GA693_RS04330	COG0284	orotidine-5'-phosphate decarboxylase activity
GA693_RS04335	COG2431	L-lysine efflux transmembrane transporter activity
GA693_RS04350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GA693_RS04355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GA693_RS04360	COG3385	transposase activity
GA693_RS04380	COG1253	flavin adenine dinucleotide binding
GA693_RS04405	COG0024	Methionine aminopeptidase
GA693_RS04410	COG0583	DNA-binding transcription factor activity
GA693_RS04425	COG3852	Histidine kinase
GA693_RS04440	COG0233	cytoplasmic translational termination
GA693_RS04445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GA693_RS04450	COG0575	Belongs to the CDS family
GA693_RS04465	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA693_RS04485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GA693_RS04515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GA693_RS04520	COG0730	response to heat
GA693_RS04525	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GA693_RS04530	COG2207	Transcriptional regulator
GA693_RS04535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GA693_RS04545	COG1960	acyl-CoA dehydrogenase activity
GA693_RS04550	COG1960	acyl-CoA dehydrogenase activity
GA693_RS04585	COG4890	Cyd operon protein YbgT
GA693_RS04590	COG1294	oxidase, subunit
GA693_RS04605	COG1585	Membrane protein implicated in regulation of membrane protease activity
GA693_RS04615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GA693_RS04635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GA693_RS04640	COG0569	domain protein
GA693_RS04650	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GA693_RS04670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GA693_RS04675	COG0542	response to heat
GA693_RS04710	COG0372	Belongs to the citrate synthase family
GA693_RS04720	COG1058	Belongs to the CinA family
GA693_RS04720	COG1546	Belongs to the CinA family
GA693_RS04755	COG2814	Major facilitator Superfamily
GA693_RS04770	COG0439	Biotin carboxylase
GA693_RS04775	COG0511	ligase activity, forming carbon-carbon bonds
GA693_RS04810	COG0596	Alpha beta hydrolase
GA693_RS04905	COG0730	response to heat
GA693_RS04910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GA693_RS04915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GA693_RS04925	COG2885	chlorophyll binding
GA693_RS04940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GA693_RS04950	COG0745	RESPONSE REGULATOR receiver
GA693_RS04970	COG1012	belongs to the aldehyde dehydrogenase family
GA693_RS04975	COG1309	transcriptional regulator
GA693_RS04980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GA693_RS05015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA693_RS05045	COG0515	serine threonine protein kinase
GA693_RS05050	COG2116	formate transmembrane transporter activity
GA693_RS05055	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GA693_RS05065	COG2223	nitrite transmembrane transporter activity
GA693_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS05105	COG2814	Major facilitator Superfamily
GA693_RS05110	COG0583	DNA-binding transcription factor activity
GA693_RS05115	COG4948	Mandelate Racemase Muconate Lactonizing
GA693_RS05120	COG4829	muconolactone delta-isomerase
GA693_RS05130	COG4638	Rieske (2fe-2S)
GA693_RS05135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GA693_RS05140	COG0543	2 iron, 2 sulfur cluster binding
GA693_RS05140	COG0633	Ferredoxin
GA693_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS05150	COG3135	benzoate transporter
GA693_RS05155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GA693_RS05160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GA693_RS05165	COG0183	Belongs to the thiolase family
GA693_RS05170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA693_RS05190	COG0583	DNA-binding transcription factor activity
GA693_RS05210	COG0303	'Molybdopterin
GA693_RS05215	COG0315	cyclic pyranopterin monophosphate synthase activity
GA693_RS05215	COG0521	Mo-molybdopterin cofactor biosynthetic process
GA693_RS05230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GA693_RS05240	COG0243	molybdopterin cofactor binding
GA693_RS05245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA693_RS05250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA693_RS05255	COG2223	nitrite transmembrane transporter activity
GA693_RS05265	COG1116	anion transmembrane transporter activity
GA693_RS05265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GA693_RS05270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GA693_RS05275	COG2937	Belongs to the GPAT DAPAT family
GA693_RS05280	COG0640	Transcriptional regulator
GA693_RS05300	COG3122	Protein conserved in bacteria
GA693_RS05305	COG0668	transmembrane transport
GA693_RS05320	COG1132	(ABC) transporter
GA693_RS05340	COG2814	Major facilitator Superfamily
GA693_RS05350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GA693_RS05360	COG1113	amino acid transport
GA693_RS05375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GA693_RS05380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GA693_RS05435	COG1525	nuclease
GA693_RS05445	COG1294	oxidase, subunit
GA693_RS05460	COG2814	Major facilitator Superfamily
GA693_RS05465	COG2207	Transcriptional regulator
GA693_RS05470	COG1960	acyl-CoA dehydrogenase activity
GA693_RS05480	COG1629	transport
GA693_RS05495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GA693_RS05520	COG0583	DNA-binding transcription factor activity
GA693_RS05530	COG1346	cytolysis
GA693_RS05540	COG1283	sodium-dependent phosphate transmembrane transporter activity
GA693_RS05550	COG0693	protein deglycase activity
GA693_RS05595	COG0552	protein localization to endoplasmic reticulum
GA693_RS05600	COG0612	Peptidase, M16
GA693_RS05630	COG0517	IMP dehydrogenase activity
GA693_RS05630	COG0516	GMP reductase activity
GA693_RS05635	COG0133	tryptophan synthase activity
GA693_RS05645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GA693_RS05665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GA693_RS05720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GA693_RS05750	COG0822	iron-sulfur transferase activity
GA693_RS05755	COG0316	Belongs to the HesB IscA family
GA693_RS05785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GA693_RS05800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GA693_RS05805	COG0702	epimerase
GA693_RS05810	COG0268	Binds directly to 16S ribosomal RNA
GA693_RS05825	COG1218	3'(2'),5'-bisphosphate nucleotidase
GA693_RS05830	COG1011	Hydrolase
GA693_RS05835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GA693_RS05845	COG2137	regulation of response to DNA damage stimulus
GA693_RS05860	COG0772	Belongs to the SEDS family
GA693_RS05875	COG0148	phosphopyruvate hydratase activity
GA693_RS05905	COG1902	pentaerythritol trinitrate reductase activity
GA693_RS05905	COG0446	pyridine nucleotide-disulphide oxidoreductase
GA693_RS05920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GA693_RS05925	COG2814	Major facilitator Superfamily
GA693_RS05930	COG1960	acyl-CoA dehydrogenase activity
GA693_RS05935	COG0583	DNA-binding transcription factor activity
GA693_RS05940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GA693_RS05945	COG1027	Aspartate ammonia-lyase
GA693_RS05950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GA693_RS05960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GA693_RS05960	COG0506	proline dehydrogenase activity
GA693_RS05960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GA693_RS05980	COG3698	Phosphodiester glycosidase
GA693_RS06020	COG0697	spore germination
GA693_RS06045	COG0424	maF-like protein
GA693_RS06050	COG2850	peptidyl-arginine hydroxylation
GA693_RS06055	COG4585	Histidine kinase
GA693_RS06065	COG0069	glutamate synthase activity
GA693_RS06085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GA693_RS06090	COG1454	alcohol dehydrogenase
GA693_RS06095	COG0824	Thioesterase
GA693_RS06100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GA693_RS06125	COG0183	Belongs to the thiolase family
GA693_RS06140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GA693_RS06150	COG3135	benzoate transporter
GA693_RS06160	COG0589	response to stress
GA693_RS06165	COG0589	response to stress
GA693_RS06175	COG0308	aminopeptidase N
GA693_RS06240	COG0477	Major facilitator Superfamily
GA693_RS06245	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GA693_RS06255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GA693_RS06265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GA693_RS06275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GA693_RS06280	COG1960	acyl-CoA dehydrogenase activity
GA693_RS06300	COG3781	membrane
GA693_RS06310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GA693_RS06325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GA693_RS06350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GA693_RS06355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GA693_RS06360	COG1845	cytochrome c oxidase, subunit III
GA693_RS06365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GA693_RS06375	COG0360	Binds together with S18 to 16S ribosomal RNA
GA693_RS06380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GA693_RS06390	COG0305	Participates in initiation and elongation during chromosome replication
GA693_RS06395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GA693_RS06410	COG1305	Transglutaminase-like
GA693_RS06420	COG2308	Evidence 4 Homologs of previously reported genes of
GA693_RS06460	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GA693_RS06465	COG0138	bifunctional purine biosynthesis protein purh
GA693_RS06485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GA693_RS06490	COG2011	ABC-type metal ion transport system permease component
GA693_RS06520	COG1454	alcohol dehydrogenase
GA693_RS06535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GA693_RS06545	COG4122	O-methyltransferase activity
GA693_RS06580	COG1137	ATPase activity
GA693_RS06585	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GA693_RS06595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GA693_RS06600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GA693_RS06600	COG0517	IMP dehydrogenase activity
GA693_RS06625	COG1643	Atp-dependent helicase
GA693_RS06630	COG0450	alkyl hydroperoxide reductase
GA693_RS06655	COG3634	alkyl hydroperoxide reductase activity
GA693_RS06670	COG2391	methyltransferase activity
GA693_RS06695	COG2070	2-Nitropropane dioxygenase
GA693_RS06705	COG0675	Transposase, IS605 OrfB family
GA693_RS06715	COG1278	Cold shock
GA693_RS06750	COG1309	transcriptional regulator
GA693_RS06755	COG0596	Alpha beta hydrolase
GA693_RS06785	COG3328	transposase activity
GA693_RS06790	COG2801	Transposase and inactivated derivatives
GA693_RS06805	COG0352	thiamine-phosphate diphosphorylase activity
GA693_RS06840	COG0612	Peptidase, M16
GA693_RS06850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GA693_RS06860	COG0739	heme binding
GA693_RS06870	COG1187	pseudouridine synthase activity
GA693_RS06885	COG1686	Belongs to the peptidase S11 family
GA693_RS06890	COG1252	NADH dehydrogenase
GA693_RS06895	COG1047	Peptidyl-prolyl cis-trans
GA693_RS06920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GA693_RS06925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GA693_RS06935	COG0693	protein deglycase activity
GA693_RS06940	COG1960	acyl-CoA dehydrogenase activity
GA693_RS06945	COG1301	dicarboxylic acid transport
GA693_RS06960	COG3139	Protein of unknown function (DUF1315)
GA693_RS06965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GA693_RS06970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GA693_RS06990	COG0642	Histidine kinase
GA693_RS06995	COG0745	RESPONSE REGULATOR receiver
GA693_RS07005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GA693_RS07020	COG1720	tRNA m6t6A37 methyltransferase activity
GA693_RS07045	COG0789	Transcriptional regulator
GA693_RS07050	COG0431	NADPH-dependent FMN reductase
GA693_RS07055	COG0798	PFAM Bile acid sodium symporter
GA693_RS07065	COG0640	Transcriptional regulator
GA693_RS07080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GA693_RS07085	COG3634	alkyl hydroperoxide reductase activity
GA693_RS07105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GA693_RS07160	COG1131	(ABC) transporter
GA693_RS07165	COG0842	Transport permease protein
GA693_RS07180	COG2951	lytic endotransglycosylase activity
GA693_RS07205	COG0052	Belongs to the universal ribosomal protein uS2 family
GA693_RS07210	COG0024	Methionine aminopeptidase
GA693_RS07225	COG2175	clavaminate synthase activity
GA693_RS07235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GA693_RS07240	COG1960	acyl-CoA dehydrogenase activity
GA693_RS07255	COG1473	amidohydrolase
GA693_RS07265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GA693_RS07270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GA693_RS07275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GA693_RS07295	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GA693_RS07325	COG2871	sodium ion transport
GA693_RS07365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GA693_RS07365	COG2885	chlorophyll binding
GA693_RS07385	COG3293	Transposase
GA693_RS07395	COG1228	amidohydrolase
GA693_RS07410	COG1902	pentaerythritol trinitrate reductase activity
GA693_RS07410	COG0446	pyridine nucleotide-disulphide oxidoreductase
GA693_RS07425	COG3706	GGDEF domain
GA693_RS07425	COG5001	Diguanylate cyclase
GA693_RS07425	COG4251	negative regulation of phosphorylation
GA693_RS07425	COG2203	Gaf domain
GA693_RS07430	COG0418	dihydroorotase activity
GA693_RS07435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GA693_RS07455	COG0833	amino acid
GA693_RS07485	COG4172	Belongs to the ABC transporter superfamily
GA693_RS07490	COG4239	(ABC) transporter, permease
GA693_RS07495	COG4174	ABC transporter (Permease)
GA693_RS07500	COG4166	transmembrane transport
GA693_RS07505	COG1388	LysM domain
GA693_RS07505	COG0741	lytic transglycosylase activity
GA693_RS07510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GA693_RS07555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA693_RS07560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA693_RS07570	COG0006	proline dipeptidase activity
GA693_RS07575	COG3079	Belongs to the UPF0149 family
GA693_RS07595	COG3706	GGDEF domain
GA693_RS07595	COG0745	RESPONSE REGULATOR receiver
GA693_RS07610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GA693_RS07620	COG2234	aminopeptidase activity
GA693_RS07630	COG3384	dioxygenase
GA693_RS07640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GA693_RS07645	COG2878	Part of a membrane complex involved in electron transport
GA693_RS07650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GA693_RS07675	COG0768	penicillin binding
GA693_RS07680	COG0742	ribosomal rna small subunit methyltransferase
GA693_RS07695	COG0830	nickel cation binding
GA693_RS07700	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GA693_RS07715	COG0804	urea catabolic process
GA693_RS07735	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS07745	COG0204	Acyl-transferase
GA693_RS07750	COG3015	lipoprotein NlpE involved in copper resistance
GA693_RS07770	COG1253	flavin adenine dinucleotide binding
GA693_RS07790	COG3118	belongs to the thioredoxin family
GA693_RS07800	COG0175	sulfate reduction
GA693_RS07820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GA693_RS07825	COG1773	rubredoxin
GA693_RS07830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GA693_RS07840	COG0583	DNA-binding transcription factor activity
GA693_RS07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GA693_RS07860	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GA693_RS07865	COG4181	ATPase activity
GA693_RS07890	COG4771	TonB-dependent receptor
GA693_RS07915	COG0306	phosphate transporter
GA693_RS07925	COG2066	Belongs to the glutaminase family
GA693_RS07980	COG2203	Gaf domain
GA693_RS07980	COG2199	diguanylate cyclase activity
GA693_RS07990	COG4681	YaeQ
GA693_RS07995	COG0523	cobalamin synthesis protein
GA693_RS08015	COG0583	DNA-binding transcription factor activity
GA693_RS08020	COG2814	Major facilitator Superfamily
GA693_RS08025	COG1309	transcriptional regulator
GA693_RS08030	COG1607	acyl-coa hydrolase
GA693_RS08040	COG1752	Esterase of the alpha-beta hydrolase superfamily
GA693_RS08045	COG2059	Chromate
GA693_RS08050	COG1115	amino acid carrier protein
GA693_RS08055	COG0786	glutamate:sodium symporter activity
GA693_RS08070	COG2814	Major facilitator Superfamily
GA693_RS08075	COG1289	transmembrane transporter activity
GA693_RS08085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GA693_RS08140	COG1376	ErfK ybiS ycfS ynhG family protein
GA693_RS08145	COG2832	Protein of unknown function (DUF454)
GA693_RS08155	COG5510	response to toxic substance
GA693_RS08175	COG0840	transmembrane signaling receptor activity
GA693_RS08210	COG0442	prolyl-tRNA aminoacylation
GA693_RS08260	COG0489	protein tyrosine kinase activity
GA693_RS08265	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GA693_RS08265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GA693_RS08305	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GA693_RS08325	COG2081	HI0933 family
GA693_RS08335	COG0668	transmembrane transport
GA693_RS08360	COG0583	DNA-binding transcription factor activity
GA693_RS08370	COG1278	Cold shock
GA693_RS08385	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GA693_RS08390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GA693_RS08395	COG0713	ATP synthesis coupled electron transport
GA693_RS08400	COG0839	Belongs to the complex I subunit 6 family
GA693_RS08405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GA693_RS08410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GA693_RS08420	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GA693_RS08440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GA693_RS08450	COG0142	geranyltranstransferase activity
GA693_RS08455	COG2828	Protein conserved in bacteria
GA693_RS08460	COG1113	amino acid transport
GA693_RS08480	COG0625	glutathione transferase activity
GA693_RS08520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GA693_RS08540	COG1530	ribonuclease E activity
GA693_RS08545	COG0424	maF-like protein
GA693_RS08550	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GA693_RS08555	COG1792	Involved in formation and maintenance of cell shape
GA693_RS08560	COG1077	Cell shape determining protein MreB Mrl
GA693_RS08565	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GA693_RS08570	COG0154	amidase activity
GA693_RS08575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GA693_RS08600	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GA693_RS08615	COG1215	transferase activity, transferring glycosyl groups
GA693_RS08620	COG0726	polysaccharide deacetylase
GA693_RS08620	COG1649	PFAM Uncharacterised BCR, COG1649
GA693_RS08640	COG3177	Filamentation induced by cAMP protein fic
GA693_RS08655	COG3188	usher protein
GA693_RS08695	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GA693_RS08720	COG2184	nucleotidyltransferase activity
GA693_RS08760	COG0582	viral genome integration into host DNA
GA693_RS08770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GA693_RS08775	COG2050	protein possibly involved in aromatic compounds catabolism
GA693_RS08795	COG0420	3'-5' exonuclease activity
GA693_RS08825	COG0735	belongs to the Fur family
GA693_RS08830	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA693_RS08835	COG2914	Belongs to the UPF0125 (RnfH) family
GA693_RS08850	COG0121	glutamine amidotransferase
GA693_RS08865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GA693_RS08870	COG0756	dUTP diphosphatase activity
GA693_RS08875	COG0210	DNA helicase
GA693_RS08880	COG2885	chlorophyll binding
GA693_RS08885	COG0204	Acyl-transferase
GA693_RS08895	COG0850	regulation of cytokinetic process
GA693_RS08900	COG2894	cell division
GA693_RS08915	COG1674	ftsk spoiiie
GA693_RS08915	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GA693_RS08920	COG0492	ferredoxin-NADP+ reductase activity
GA693_RS08925	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GA693_RS08935	COG0456	acetyltransferase
GA693_RS08960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GA693_RS08980	COG1113	amino acid transport
GA693_RS08985	COG0251	oxidation-reduction process
GA693_RS09000	COG1522	sequence-specific DNA binding
GA693_RS09010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GA693_RS09010	COG0352	thiamine-phosphate diphosphorylase activity
GA693_RS09010	COG0351	phosphomethylpyrimidine kinase
GA693_RS09025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GA693_RS09040	COG2132	Multicopper oxidase
GA693_RS09050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GA693_RS09065	COG4269	membrane
GA693_RS09085	COG1968	undecaprenyl-diphosphatase activity
GA693_RS09090	COG1214	PFAM Peptidase M22, glycoprotease
GA693_RS09100	COG0494	nUDIX hydrolase
GA693_RS09150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GA693_RS09155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GA693_RS09220	COG2199	diguanylate cyclase activity
GA693_RS09250	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GA693_RS09255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GA693_RS09270	COG0450	alkyl hydroperoxide reductase
GA693_RS09285	COG0285	dihydrofolate synthase activity
GA693_RS09290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GA693_RS09325	COG0133	tryptophan synthase activity
GA693_RS09335	COG4206	TonB-dependent receptor
GA693_RS09340	COG2096	Adenosyltransferase
GA693_RS09360	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GA693_RS09365	COG2315	Protein conserved in bacteria
GA693_RS09375	COG0745	RESPONSE REGULATOR receiver
GA693_RS09380	COG2205	protein histidine kinase activity
GA693_RS09390	COG1960	acyl-CoA dehydrogenase activity
GA693_RS09395	COG1960	acyl-CoA dehydrogenase activity
GA693_RS09400	COG3223	Belongs to the PsiE family
GA693_RS09430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GA693_RS09445	COG0463	Glycosyl transferase, family 2
GA693_RS09475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GA693_RS09480	COG5002	protein histidine kinase activity
GA693_RS09495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GA693_RS09505	COG1704	LemA family
GA693_RS09510	COG5001	Diguanylate cyclase
GA693_RS09510	COG4251	negative regulation of phosphorylation
GA693_RS09510	COG2203	Gaf domain
GA693_RS09510	COG3706	GGDEF domain
GA693_RS09520	COG1862	Preprotein translocase
GA693_RS09530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GA693_RS09540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GA693_RS09555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GA693_RS09560	COG5002	protein histidine kinase activity
GA693_RS09560	COG2205	protein histidine kinase activity
GA693_RS09560	COG0784	Response regulator, receiver
GA693_RS09565	COG1024	Enoyl-CoA hydratase
GA693_RS09575	COG3622	Belongs to the hyi family
GA693_RS09585	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GA693_RS09590	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GA693_RS09595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GA693_RS09600	COG0697	spore germination
GA693_RS09605	COG2814	Major facilitator Superfamily
GA693_RS09625	COG1058	Belongs to the CinA family
GA693_RS09625	COG1546	Belongs to the CinA family
GA693_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
GA693_RS09660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GA693_RS09670	COG1960	acyl-CoA dehydrogenase activity
GA693_RS09675	COG1960	acyl-CoA dehydrogenase activity
GA693_RS09680	COG1024	Enoyl-CoA hydratase
GA693_RS09685	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA693_RS09690	COG0183	Belongs to the thiolase family
GA693_RS09710	COG2814	Major facilitator Superfamily
GA693_RS09715	COG1024	Enoyl-CoA hydratase
GA693_RS09720	COG1846	Transcriptional regulator
GA693_RS09750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GA693_RS09755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GA693_RS09760	COG0084	hydrolase, TatD family'
GA693_RS09775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GA693_RS09790	COG0793	Belongs to the peptidase S41A family
GA693_RS09820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GA693_RS09825	COG0857	belongs to the CobB CobQ family
GA693_RS09825	COG0280	phosphate acetyltransferase
GA693_RS09835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GA693_RS09835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GA693_RS09850	COG0740	serine-type endopeptidase activity
GA693_RS09860	COG4771	TonB-dependent receptor
GA693_RS09865	COG4774	siderophore transport
GA693_RS09870	COG3128	pkhd-type hydroxylase
GA693_RS09880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GA693_RS09885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA693_RS09890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GA693_RS09890	COG2813	Specifically methylates the guanine in position
GA693_RS09950	COG3040	lipid binding
GA693_RS09980	COG0179	Fumarylacetoacetate (FAA) hydrolase
GA693_RS10015	COG0557	exoribonuclease II activity
GA693_RS10020	COG0339	signal peptide processing
GA693_RS10025	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GA693_RS10040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GA693_RS10065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GA693_RS10070	COG1960	acyl-CoA dehydrogenase activity
GA693_RS10075	COG2072	flavoprotein involved in K transport
GA693_RS10085	COG0202	RNA polymerase activity
GA693_RS10090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GA693_RS10095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GA693_RS10105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GA693_RS10125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GA693_RS10135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GA693_RS10140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GA693_RS10150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GA693_RS10175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GA693_RS10205	COG0088	Forms part of the polypeptide exit tunnel
GA693_RS10230	COG0433	COG0433 Predicted ATPase
GA693_RS10235	COG1017	nitric oxide dioxygenase activity
GA693_RS10235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GA693_RS10240	COG1959	2 iron, 2 sulfur cluster binding
GA693_RS10260	COG1301	dicarboxylic acid transport
GA693_RS10265	COG1946	Acyl-CoA thioesterase
GA693_RS10270	COG2937	Belongs to the GPAT DAPAT family
GA693_RS10280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GA693_RS10285	COG1040	competence protein
GA693_RS10300	COG0598	Magnesium transport protein CorA
GA693_RS10310	COG2854	intermembrane phospholipid transfer
GA693_RS10315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GA693_RS10320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GA693_RS10325	COG1127	ABC transporter
GA693_RS10350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GA693_RS10355	COG0408	coproporphyrinogen oxidase activity
GA693_RS10370	COG1960	acyl-CoA dehydrogenase activity
GA693_RS10375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GA693_RS10385	COG0534	Mate efflux family protein
GA693_RS10390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GA693_RS10395	COG0254	rRNA binding
GA693_RS10400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GA693_RS10420	COG2226	methyltransferase
GA693_RS10425	COG1943	Transposase
GA693_RS10465	COG1192	Involved in chromosome partitioning
GA693_RS10470	COG0628	permease
GA693_RS10480	COG2814	Major facilitator Superfamily
GA693_RS10495	COG0277	FAD linked oxidase domain protein
GA693_RS10500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GA693_RS10525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GA693_RS10530	COG5380	lipid catabolic process
GA693_RS10535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GA693_RS10560	COG0335	large ribosomal subunit rRNA binding
GA693_RS10570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GA693_RS10575	COG0228	four-way junction DNA binding
GA693_RS10620	COG0194	GDP metabolic process
GA693_RS10625	COG1758	RNA polymerase activity
GA693_RS10630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GA693_RS10640	COG2906	2 iron, 2 sulfur cluster binding
GA693_RS10650	COG3307	-O-antigen
GA693_RS10660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GA693_RS10660	COG2755	lipolytic protein G-D-S-L family
GA693_RS10690	COG1704	LemA family
GA693_RS10695	COG0493	'glutamate synthase
GA693_RS10700	COG0070	glutamate synthase
GA693_RS10700	COG0067	glutamate synthase
GA693_RS10700	COG0069	glutamate synthase activity
GA693_RS10750	COG2226	methyltransferase
GA693_RS10760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GA693_RS10765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GA693_RS10780	COG0275	rRNA processing
GA693_RS10785	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GA693_RS10795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GA693_RS10815	COG0488	(ABC) transporter
GA693_RS10825	COG4221	oxidoreductase activity
GA693_RS10840	COG0745	RESPONSE REGULATOR receiver
GA693_RS10845	COG2205	protein histidine kinase activity
GA693_RS10850	COG0427	acetyl-CoA hydrolase
GA693_RS10880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GA693_RS10900	COG0697	spore germination
GA693_RS10915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GA693_RS10955	COG3158	transport of potassium into the cell
GA693_RS10980	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GA693_RS10990	COG0450	alkyl hydroperoxide reductase
GA693_RS11010	COG3077	Addiction module antitoxin, RelB DinJ family
GA693_RS11025	COG2132	Multicopper oxidase
GA693_RS11055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GA693_RS11135	COG3316	Transposase and inactivated derivatives
GA693_RS11140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GA693_RS11185	COG2217	Heavy metal translocating P-type atpase
GA693_RS11190	COG3174	membrane
GA693_RS11195	COG2205	protein histidine kinase activity
GA693_RS11210	COG2132	Multicopper oxidase
GA693_RS11270	COG0629	single-stranded DNA binding
GA693_RS11275	COG2814	Major facilitator Superfamily
GA693_RS11285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GA693_RS11290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GA693_RS11295	COG3706	GGDEF domain
GA693_RS11305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GA693_RS11320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GA693_RS11325	COG3162	membrane
GA693_RS11330	COG0784	Response regulator, receiver
GA693_RS11330	COG2205	protein histidine kinase activity
GA693_RS11345	COG0431	NADPH-dependent FMN reductase
GA693_RS11355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GA693_RS11360	COG0668	transmembrane transport
GA693_RS11365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GA693_RS11370	COG1519	Transferase
GA693_RS11375	COG1902	pentaerythritol trinitrate reductase activity
GA693_RS11395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GA693_RS11420	COG0426	domain, Protein
GA693_RS11420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GA693_RS11425	COG2119	membrane
GA693_RS11455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GA693_RS11465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GA693_RS11475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GA693_RS11480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GA693_RS11485	COG0189	ligase activity
GA693_RS11505	COG0708	Exodeoxyribonuclease III
GA693_RS11510	COG1393	Belongs to the ArsC family
GA693_RS11525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GA693_RS11530	COG3706	GGDEF domain
GA693_RS11535	COG0625	glutathione transferase activity
GA693_RS11575	COG1247	-acetyltransferase
GA693_RS11580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GA693_RS11585	COG4266	Belongs to the allantoicase family
GA693_RS11590	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GA693_RS11605	COG0471	metal ion transport
GA693_RS11615	COG0410	ABC transporter
GA693_RS11630	COG0559	Belongs to the binding-protein-dependent transport system permease family
GA693_RS11645	COG3150	esterase
GA693_RS11655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GA693_RS11660	COG2918	glutathione biosynthetic process
GA693_RS11675	COG2733	membrane
GA693_RS11680	COG0436	Aminotransferase
GA693_RS11685	COG0534	Mate efflux family protein
GA693_RS11690	COG2175	clavaminate synthase activity
GA693_RS11735	COG0753	catalase activity
GA693_RS11755	COG3830	Belongs to the UPF0237 family
GA693_RS11755	COG0560	Phosphoserine phosphatase
GA693_RS11770	COG0385	Bile acid
GA693_RS11775	COG1335	isochorismatase
GA693_RS11780	COG2814	Major facilitator Superfamily
GA693_RS11785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GA693_RS11795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GA693_RS11800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GA693_RS11805	COG2983	Belongs to the UPF0260 family
GA693_RS11810	COG5487	UPF0391 membrane protein
GA693_RS11825	COG1194	a g-specific adenine glycosylase
GA693_RS11830	COG0739	heme binding
GA693_RS11840	COG2818	Glycosylase
GA693_RS11845	COG1064	alcohol dehydrogenase
GA693_RS11865	COG3023	N-Acetylmuramoyl-L-alanine amidase
GA693_RS11875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GA693_RS11880	COG1309	transcriptional regulator
GA693_RS11890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GA693_RS11895	COG0546	phosphoglycolate phosphatase activity
GA693_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS11930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GA693_RS11930	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GA693_RS11935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GA693_RS11940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GA693_RS11945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GA693_RS11950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GA693_RS11955	COG1116	anion transmembrane transporter activity
GA693_RS11960	COG1309	transcriptional regulator
GA693_RS11970	COG0196	riboflavin kinase activity
GA693_RS11975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GA693_RS11980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GA693_RS11985	COG1047	Peptidyl-prolyl cis-trans
GA693_RS11995	COG2133	pyrroloquinoline quinone binding
GA693_RS12000	COG2814	Major facilitator Superfamily
GA693_RS12030	COG0737	Belongs to the 5'-nucleotidase family
GA693_RS12040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GA693_RS12045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GA693_RS12075	COG1943	Transposase
GA693_RS12085	COG0488	(ABC) transporter
GA693_RS12090	COG1063	alcohol dehydrogenase
GA693_RS12095	COG0187	DNA topoisomerase II activity
GA693_RS12105	COG0592	DNA-directed DNA polymerase activity
GA693_RS12110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GA693_RS12115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GA693_RS12120	COG0594	ribonuclease P activity
GA693_RS12125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GA693_RS12130	COG0706	membrane insertase activity
GA693_RS12155	COG1230	cation diffusion facilitator family transporter
GA693_RS12160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GA693_RS12175	COG0402	S-adenosylhomocysteine deaminase activity
GA693_RS12180	COG0861	Integral membrane protein TerC family
GA693_RS12190	COG2388	GCN5-related N-acetyl-transferase
GA693_RS12200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GA693_RS12220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GA693_RS12230	COG2951	lytic endotransglycosylase activity
GA693_RS12275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GA693_RS12305	COG2814	Major facilitator Superfamily
GA693_RS12330	COG1012	belongs to the aldehyde dehydrogenase family
GA693_RS12335	COG0733	neurotransmitter:sodium symporter activity
GA693_RS12345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GA693_RS12355	COG0129	dihydroxy-acid dehydratase activity
GA693_RS12365	COG0129	dihydroxy-acid dehydratase activity
GA693_RS12380	COG2233	PERMEase
GA693_RS12390	COG1309	transcriptional regulator
GA693_RS12395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GA693_RS12450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GA693_RS12465	COG0438	transferase activity, transferring glycosyl groups
GA693_RS12485	COG0438	transferase activity, transferring glycosyl groups
GA693_RS12490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GA693_RS12500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GA693_RS12510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GA693_RS12525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GA693_RS12560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GA693_RS12570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GA693_RS12585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GA693_RS12595	COG4628	conserved protein (DUF2132)
GA693_RS12660	COG1570	exodeoxyribonuclease VII activity
GA693_RS12675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GA693_RS12680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GA693_RS12695	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GA693_RS12705	COG3316	Transposase and inactivated derivatives
GA693_RS12715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GA693_RS12725	COG5002	protein histidine kinase activity
GA693_RS12750	COG1660	Displays ATPase and GTPase activities
GA693_RS12755	COG3316	Transposase and inactivated derivatives
GA693_RS12760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GA693_RS12810	COG3316	Transposase and inactivated derivatives
GA693_RS12835	COG3077	Addiction module antitoxin, RelB DinJ family
GA693_RS12855	COG2801	Transposase and inactivated derivatives
GA693_RS12875	COG3316	Transposase and inactivated derivatives
GA693_RS12890	COG4974	Belongs to the 'phage' integrase family
GA693_RS12920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GA693_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS12955	COG3756	Protein conserved in bacteria
GA693_RS12990	COG0271	Belongs to the BolA IbaG family
GA693_RS13000	COG1192	Involved in chromosome partitioning
GA693_RS13015	COG0586	Pfam SNARE associated Golgi protein
GA693_RS13020	COG2259	Doxx family
GA693_RS13025	COG0519	Catalyzes the synthesis of GMP from XMP
GA693_RS13025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GA693_RS13030	COG3706	GGDEF domain
GA693_RS13030	COG0745	RESPONSE REGULATOR receiver
GA693_RS13065	COG0281	malic enzyme
GA693_RS13070	COG3501	Rhs element vgr protein
GA693_RS13075	COG3179	chitinase
GA693_RS13095	COG2837	iron assimilation
GA693_RS13100	COG1280	lysine exporter protein (LysE YggA)
GA693_RS13105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GA693_RS13110	COG1121	(ABC) transporter
GA693_RS13150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GA693_RS13160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GA693_RS13185	COG0386	Belongs to the glutathione peroxidase family
GA693_RS13190	COG0697	spore germination
GA693_RS13200	COG0758	DNA mediated transformation
GA693_RS13250	COG2814	Major facilitator Superfamily
GA693_RS13270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GA693_RS13285	COG2814	Major facilitator Superfamily
GA693_RS13305	COG1253	flavin adenine dinucleotide binding
GA693_RS13315	COG2860	membrane
GA693_RS13320	COG0477	Major facilitator Superfamily
GA693_RS13330	COG0318	PFAM AMP-dependent synthetase and ligase
GA693_RS13345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GA693_RS13360	COG0606	chelatase, subunit chli
GA693_RS13370	COG0347	Belongs to the P(II) protein family
GA693_RS13375	COG0004	ammonium transporteR
GA693_RS13385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GA693_RS13385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GA693_RS13400	COG0586	Pfam SNARE associated Golgi protein
GA693_RS13405	COG3385	transposase activity
GA693_RS13430	COG0795	lipopolysaccharide-transporting ATPase activity
GA693_RS13435	COG0795	lipopolysaccharide-transporting ATPase activity
GA693_RS13440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GA693_RS13445	COG0793	Belongs to the peptidase S41A family
GA693_RS13460	COG2197	response regulator
GA693_RS13470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GA693_RS13485	COG4974	Belongs to the 'phage' integrase family
GA693_RS13510	COG0772	Belongs to the SEDS family
GA693_RS13520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GA693_RS13525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GA693_RS13530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GA693_RS13535	COG0494	nUDIX hydrolase
GA693_RS13570	COG3275	phosphorelay sensor kinase activity
GA693_RS13580	COG0181	hydroxymethylbilane synthase activity
GA693_RS13600	COG0824	Thioesterase
GA693_RS13625	COG1716	ATPase activity
GA693_RS13630	COG0546	phosphoglycolate phosphatase activity
GA693_RS13685	COG0081	regulation of translation
GA693_RS13700	COG0085	RNA polymerase activity
GA693_RS13705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GA693_RS13725	COG2056	Na+-H+ antiporter family
GA693_RS13740	COG0326	Molecular chaperone. Has ATPase activity
GA693_RS13765	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GA693_RS13775	COG2233	PERMEase
GA693_RS13785	COG1024	Enoyl-CoA hydratase
GA693_RS13785	COG1250	3-hydroxyacyl-CoA dehydrogenase
GA693_RS13815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GA693_RS13820	COG1132	(ABC) transporter
GA693_RS13835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GA693_RS13845	COG0497	DNA recombination
GA693_RS13850	COG3123	guanosine phosphorylase activity
GA693_RS13855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GA693_RS13865	COG0237	dephospho-CoA kinase activity
GA693_RS13915	COG0779	Required for maturation of 30S ribosomal subunits
GA693_RS13920	COG0195	Participates in both transcription termination and antitermination
GA693_RS13930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GA693_RS13935	COG3385	transposase activity
GA693_RS13945	COG2212	antiporter activity
GA693_RS13955	COG0651	ATP synthesis coupled electron transport
GA693_RS13960	COG1006	Multisubunit Na H antiporter MnhC subunit
GA693_RS13965	COG2111	Na H antiporter
GA693_RS13965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GA693_RS13980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GA693_RS13990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GA693_RS14020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GA693_RS14025	COG1074	ATP-dependent DNA helicase activity
GA693_RS14030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GA693_RS14035	COG0675	Transposase, IS605 OrfB family
GA693_RS14040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GA693_RS14055	COG2841	Protein conserved in bacteria
GA693_RS14060	COG0789	Transcriptional regulator
GA693_RS14070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GA693_RS14080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GA693_RS14095	COG2165	general secretion pathway protein
GA693_RS14105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GA693_RS14110	COG4535	Mg2 and Co2 transporter CorC
GA693_RS14115	COG0425	Belongs to the sulfur carrier protein TusA family
GA693_RS14120	COG3501	Rhs element vgr protein
GA693_RS14160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GA693_RS14160	COG0644	oxidoreductase
GA693_RS14170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GA693_RS14185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GA693_RS14195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GA693_RS14205	COG0493	'glutamate synthase
GA693_RS14205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GA693_RS14230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GA693_RS14260	COG0751	glycine-tRNA ligase activity
GA693_RS14275	COG1983	PspC domain protein
GA693_RS14305	COG1530	ribonuclease E activity
GA693_RS14315	COG0546	phosphoglycolate phosphatase activity
GA693_RS14320	COG3971	2-oxopent-4-enoate hydratase activity
GA693_RS14325	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GA693_RS14350	COG0583	DNA-binding transcription factor activity
GA693_RS14355	COG4638	Rieske (2fe-2S)
GA693_RS14370	COG1028	Short-chain dehydrogenase reductase Sdr
GA693_RS14375	COG3384	dioxygenase
GA693_RS14380	COG0446	pyridine nucleotide-disulphide oxidoreductase
GA693_RS14395	COG0753	catalase activity
GA693_RS14405	COG1960	acyl-CoA dehydrogenase activity
GA693_RS14425	COG0494	nUDIX hydrolase
GA693_RS14455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GA693_RS14470	COG0473	3-isopropylmalate dehydrogenase activity
GA693_RS14525	COG1560	Kdo2-lipid A biosynthetic process
GA693_RS14565	COG1929	Belongs to the glycerate kinase type-1 family
GA693_RS14575	COG0210	DNA helicase
GA693_RS14580	COG0724	RNA recognition motif
GA693_RS14595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GA693_RS14595	COG4651	solute:proton antiporter activity
GA693_RS14600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GA693_RS14605	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GA693_RS14620	COG0788	formyltetrahydrofolate deformylase activity
GA693_RS14650	COG1295	ribonuclease BN
GA693_RS14700	COG1702	phosphate starvation-inducible protein PhoH
GA693_RS14705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GA693_RS14710	COG0741	lytic transglycosylase activity
GA693_RS14710	COG0739	heme binding
GA693_RS14710	COG1196	nuclear chromosome segregation