locus-tag	class	description
GK020_RS00010	COG0592	DNA-directed DNA polymerase activity
GK020_RS00020	COG0187	DNA topoisomerase II activity
GK020_RS00025	COG1063	alcohol dehydrogenase
GK020_RS00030	COG3328	transposase activity
GK020_RS00035	COG0488	(ABC) transporter
GK020_RS00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GK020_RS00080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GK020_RS00130	COG2814	Major facilitator Superfamily
GK020_RS00140	COG1012	belongs to the aldehyde dehydrogenase family
GK020_RS00145	COG0733	neurotransmitter:sodium symporter activity
GK020_RS00155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GK020_RS00170	COG0129	dihydroxy-acid dehydratase activity
GK020_RS00185	COG2233	PERMEase
GK020_RS00195	COG1309	transcriptional regulator
GK020_RS00200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GK020_RS00255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GK020_RS00280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GK020_RS00295	COG2030	dehydratase
GK020_RS00300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GK020_RS00330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GK020_RS00345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GK020_RS00360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GK020_RS00370	COG2801	Transposase and inactivated derivatives
GK020_RS00400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GK020_RS00410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GK020_RS00425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GK020_RS00435	COG4628	conserved protein (DUF2132)
GK020_RS00460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GK020_RS00465	COG3550	peptidyl-serine autophosphorylation
GK020_RS00575	COG4372	Transposase
GK020_RS00635	COG3586	endonuclease activity
GK020_RS00655	COG3756	Protein conserved in bacteria
GK020_RS00690	COG0271	Belongs to the BolA IbaG family
GK020_RS00700	COG1192	Involved in chromosome partitioning
GK020_RS00715	COG0586	Pfam SNARE associated Golgi protein
GK020_RS00720	COG2259	Doxx family
GK020_RS00725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GK020_RS00725	COG0519	Catalyzes the synthesis of GMP from XMP
GK020_RS00770	COG0281	malic enzyme
GK020_RS00780	COG3179	chitinase
GK020_RS00795	COG2837	iron assimilation
GK020_RS00805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GK020_RS00810	COG1121	(ABC) transporter
GK020_RS00860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GK020_RS00890	COG4372	Transposase
GK020_RS00950	COG0386	Belongs to the glutathione peroxidase family
GK020_RS00955	COG0697	spore germination
GK020_RS00965	COG0758	DNA mediated transformation
GK020_RS01020	COG2814	Major facilitator Superfamily
GK020_RS01040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GK020_RS01055	COG2814	Major facilitator Superfamily
GK020_RS01085	COG1253	flavin adenine dinucleotide binding
GK020_RS01095	COG2860	membrane
GK020_RS01100	COG0477	Major facilitator Superfamily
GK020_RS01115	COG0318	PFAM AMP-dependent synthetase and ligase
GK020_RS01130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GK020_RS01145	COG0606	chelatase, subunit chli
GK020_RS01155	COG0347	Belongs to the P(II) protein family
GK020_RS01160	COG0004	ammonium transporteR
GK020_RS01170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GK020_RS01170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GK020_RS01185	COG0586	Pfam SNARE associated Golgi protein
GK020_RS01210	COG0795	lipopolysaccharide-transporting ATPase activity
GK020_RS01215	COG0795	lipopolysaccharide-transporting ATPase activity
GK020_RS01220	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GK020_RS01225	COG0793	Belongs to the peptidase S41A family
GK020_RS01240	COG2197	response regulator
GK020_RS01250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GK020_RS01265	COG4974	Belongs to the 'phage' integrase family
GK020_RS01290	COG0772	Belongs to the SEDS family
GK020_RS01300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GK020_RS01305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GK020_RS01310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GK020_RS01315	COG0494	nUDIX hydrolase
GK020_RS01355	COG3275	phosphorelay sensor kinase activity
GK020_RS01365	COG0181	hydroxymethylbilane synthase activity
GK020_RS01385	COG0824	Thioesterase
GK020_RS01415	COG0546	phosphoglycolate phosphatase activity
GK020_RS01470	COG0081	regulation of translation
GK020_RS01485	COG0085	RNA polymerase activity
GK020_RS01490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GK020_RS01510	COG2056	Na+-H+ antiporter family
GK020_RS01525	COG0326	Molecular chaperone. Has ATPase activity
GK020_RS01550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GK020_RS01560	COG2233	PERMEase
GK020_RS01580	COG1250	3-hydroxyacyl-CoA dehydrogenase
GK020_RS01580	COG1024	Enoyl-CoA hydratase
GK020_RS01610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GK020_RS01615	COG1132	(ABC) transporter
GK020_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GK020_RS01640	COG0497	DNA recombination
GK020_RS01645	COG3123	guanosine phosphorylase activity
GK020_RS01650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GK020_RS01660	COG0237	dephospho-CoA kinase activity
GK020_RS01710	COG0779	Required for maturation of 30S ribosomal subunits
GK020_RS01715	COG0195	Participates in both transcription termination and antitermination
GK020_RS01725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GK020_RS01730	COG1320	monovalent cation:proton antiporter activity
GK020_RS01735	COG2212	antiporter activity
GK020_RS01740	COG1863	multisubunit Na H antiporter MnhE subunit
GK020_RS01745	COG0651	ATP synthesis coupled electron transport
GK020_RS01750	COG1006	Multisubunit Na H antiporter MnhC subunit
GK020_RS01755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GK020_RS01755	COG2111	Na H antiporter
GK020_RS01770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GK020_RS01780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GK020_RS01810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GK020_RS01815	COG1074	ATP-dependent DNA helicase activity
GK020_RS01820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GK020_RS01825	COG0675	Transposase, IS605 OrfB family
GK020_RS01830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GK020_RS01845	COG2841	Protein conserved in bacteria
GK020_RS01850	COG0789	Transcriptional regulator
GK020_RS01860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GK020_RS01870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GK020_RS01890	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GK020_RS01895	COG4535	Mg2 and Co2 transporter CorC
GK020_RS01900	COG0425	Belongs to the sulfur carrier protein TusA family
GK020_RS01920	COG0644	oxidoreductase
GK020_RS01920	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GK020_RS01930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GK020_RS01945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GK020_RS01955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GK020_RS01965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GK020_RS01965	COG0493	'glutamate synthase
GK020_RS01975	COG2226	methyltransferase
GK020_RS01990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GK020_RS02020	COG0751	glycine-tRNA ligase activity
GK020_RS02030	COG0617	tRNA 3'-terminal CCA addition
GK020_RS02030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GK020_RS02030	COG0517	IMP dehydrogenase activity
GK020_RS02035	COG1983	PspC domain protein
GK020_RS02060	COG0318	PFAM AMP-dependent synthetase and ligase
GK020_RS02065	COG1530	ribonuclease E activity
GK020_RS02075	COG0546	phosphoglycolate phosphatase activity
GK020_RS02080	COG0583	DNA-binding transcription factor activity
GK020_RS02095	COG0753	catalase activity
GK020_RS02105	COG1960	acyl-CoA dehydrogenase activity
GK020_RS02125	COG0494	nUDIX hydrolase
GK020_RS02140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GK020_RS02160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GK020_RS02175	COG0473	3-isopropylmalate dehydrogenase activity
GK020_RS02230	COG1560	Kdo2-lipid A biosynthetic process
GK020_RS02235	COG0488	(ABC) transporter
GK020_RS02240	COG2900	Belongs to the SlyX family
GK020_RS02270	COG1929	Belongs to the glycerate kinase type-1 family
GK020_RS02280	COG0210	DNA helicase
GK020_RS02285	COG0724	RNA recognition motif
GK020_RS02300	COG4651	solute:proton antiporter activity
GK020_RS02300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GK020_RS02325	COG0788	formyltetrahydrofolate deformylase activity
GK020_RS02355	COG1295	ribonuclease BN
GK020_RS02405	COG1702	phosphate starvation-inducible protein PhoH
GK020_RS02415	COG0741	lytic transglycosylase activity
GK020_RS02415	COG0739	heme binding
GK020_RS02415	COG1196	nuclear chromosome segregation
GK020_RS02430	COG3385	transposase activity
GK020_RS02470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GK020_RS02475	COG1183	phosphatidylcholine synthase activity
GK020_RS02545	COG1607	acyl-coa hydrolase
GK020_RS02555	COG1666	GTP binding
GK020_RS02575	COG2350	Protein conserved in bacteria
GK020_RS02590	COG3781	membrane
GK020_RS02600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GK020_RS02610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GK020_RS02620	COG1162	GTPase activity
GK020_RS02625	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GK020_RS02660	COG4372	Transposase
GK020_RS02670	COG2963	transposase activity
GK020_RS02680	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS02690	COG2801	Transposase and inactivated derivatives
GK020_RS02730	COG0577	efflux transmembrane transporter activity
GK020_RS02730	COG1136	(ABC) transporter
GK020_RS02735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GK020_RS02765	COG0028	Belongs to the TPP enzyme family
GK020_RS02830	COG2975	iron-sulfur cluster assembly
GK020_RS02860	COG0124	histidyl-tRNA synthetase
GK020_RS02870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GK020_RS02885	COG3956	TIGRFAM MazG family protein
GK020_RS02890	COG1555	photosystem II stabilization
GK020_RS02895	COG0617	tRNA 3'-terminal CCA addition
GK020_RS02900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GK020_RS02915	COG1660	Displays ATPase and GTPase activities
GK020_RS02925	COG3028	Belongs to the UPF0307 family
GK020_RS02930	COG0318	PFAM AMP-dependent synthetase and ligase
GK020_RS02945	COG0625	glutathione transferase activity
GK020_RS02950	COG1238	metal cluster binding
GK020_RS02985	COG0072	phenylalanine-tRNA ligase activity
GK020_RS03010	COG0248	Ppx GppA phosphatase
GK020_RS03020	COG0037	tRNA processing
GK020_RS03070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GK020_RS03145	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GK020_RS03150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GK020_RS03200	COG0494	nUDIX hydrolase
GK020_RS03210	COG1214	PFAM Peptidase M22, glycoprotease
GK020_RS03215	COG1968	undecaprenyl-diphosphatase activity
GK020_RS03235	COG4269	membrane
GK020_RS03250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GK020_RS03260	COG2132	Multicopper oxidase
GK020_RS03280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GK020_RS03295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GK020_RS03295	COG0352	thiamine-phosphate diphosphorylase activity
GK020_RS03295	COG0351	phosphomethylpyrimidine kinase
GK020_RS03320	COG0251	oxidation-reduction process
GK020_RS03325	COG1113	amino acid transport
GK020_RS03330	COG1981	membrane
GK020_RS03345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GK020_RS03370	COG0456	acetyltransferase
GK020_RS03375	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GK020_RS03380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GK020_RS03385	COG0492	ferredoxin-NADP+ reductase activity
GK020_RS03390	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GK020_RS03390	COG1674	ftsk spoiiie
GK020_RS03405	COG2894	cell division
GK020_RS03410	COG0850	regulation of cytokinetic process
GK020_RS03420	COG0204	Acyl-transferase
GK020_RS03425	COG2885	chlorophyll binding
GK020_RS03430	COG0210	DNA helicase
GK020_RS03445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GK020_RS03460	COG0121	glutamine amidotransferase
GK020_RS03475	COG2914	Belongs to the UPF0125 (RnfH) family
GK020_RS03480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GK020_RS03485	COG0735	belongs to the Fur family
GK020_RS03515	COG0420	3'-5' exonuclease activity
GK020_RS03535	COG2050	protein possibly involved in aromatic compounds catabolism
GK020_RS03540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GK020_RS03550	COG0582	viral genome integration into host DNA
GK020_RS03570	COG3328	transposase activity
GK020_RS03645	COG4372	Transposase
GK020_RS03655	COG2963	transposase activity
GK020_RS03670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GK020_RS03685	COG1401	restriction endodeoxyribonuclease activity
GK020_RS03685	COG1401	restriction endodeoxyribonuclease activity
GK020_RS03695	COG0642	Histidine kinase
GK020_RS03710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GK020_RS03725	COG0640	Transcriptional regulator
GK020_RS03750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GK020_RS03755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GK020_RS03770	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS03775	COG3177	Filamentation induced by cAMP protein fic
GK020_RS03795	COG2963	transposase activity
GK020_RS03805	COG4372	Transposase
GK020_RS03815	COG3328	transposase activity
GK020_RS03830	COG1649	PFAM Uncharacterised BCR, COG1649
GK020_RS03830	COG0726	polysaccharide deacetylase
GK020_RS03835	COG1215	transferase activity, transferring glycosyl groups
GK020_RS03850	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GK020_RS03895	COG0346	lactoylglutathione lyase activity
GK020_RS03900	COG0564	pseudouridine synthase activity
GK020_RS03920	COG2824	Alkylphosphonate utilization operon protein PhnA
GK020_RS03930	COG0628	permease
GK020_RS03945	COG2801	Transposase and inactivated derivatives
GK020_RS03955	COG3328	transposase activity
GK020_RS03990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GK020_RS04010	COG0730	response to heat
GK020_RS04020	COG1196	nuclear chromosome segregation
GK020_RS04025	COG3115	cell septum assembly
GK020_RS04030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GK020_RS04035	COG2193	ferroxidase activity
GK020_RS04040	COG0596	Alpha beta hydrolase
GK020_RS04040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GK020_RS04040	COG2226	methyltransferase
GK020_RS04055	COG4106	trans-aconitate 2-methyltransferase activity
GK020_RS04070	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GK020_RS04075	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GK020_RS04085	COG0009	L-threonylcarbamoyladenylate synthase
GK020_RS04090	COG3101	peptidyl-lysine hydroxylation
GK020_RS04095	COG1399	metal-binding, possibly nucleic acid-binding protein
GK020_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
GK020_RS04120	COG1652	LysM domain
GK020_RS04125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GK020_RS04140	COG0745	RESPONSE REGULATOR receiver
GK020_RS04145	COG2205	protein histidine kinase activity
GK020_RS04150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GK020_RS04165	COG1752	Esterase of the alpha-beta hydrolase superfamily
GK020_RS04185	COG3338	carbonate dehydratase activity
GK020_RS04190	COG1126	abc transporter atp-binding protein
GK020_RS04195	COG0765	amino acid transport
GK020_RS04200	COG0765	amino acid transport
GK020_RS04210	COG2323	membrane
GK020_RS04225	COG0525	valine-tRNA ligase activity
GK020_RS04240	COG0393	Putative heavy-metal-binding
GK020_RS04245	COG0393	Putative heavy-metal-binding
GK020_RS04250	COG1538	Outer membrane efflux protein
GK020_RS04260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GK020_RS04265	COG0671	phosphoesterase, PA-phosphatase related
GK020_RS04290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GK020_RS04300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GK020_RS04305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GK020_RS04305	COG1648	precorrin-2 dehydrogenase activity
GK020_RS04310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GK020_RS04315	COG0531	amino acid
GK020_RS04330	COG0321	lipoyl(octanoyl) transferase activity
GK020_RS04365	COG0586	Pfam SNARE associated Golgi protein
GK020_RS04410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GK020_RS04440	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GK020_RS04455	COG0358	DNA primase activity
GK020_RS04465	COG0564	pseudouridine synthase activity
GK020_RS04480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GK020_RS04490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GK020_RS04520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GK020_RS04520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GK020_RS04535	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GK020_RS04550	COG2072	flavoprotein involved in K transport
GK020_RS04565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GK020_RS04570	COG1053	succinate dehydrogenase
GK020_RS04575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GK020_RS04590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GK020_RS04600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GK020_RS04610	COG1649	PFAM Uncharacterised BCR, COG1649
GK020_RS04610	COG0726	polysaccharide deacetylase
GK020_RS04615	COG1215	transferase activity, transferring glycosyl groups
GK020_RS04650	COG2268	Band 7 protein
GK020_RS04675	COG2354	Protein conserved in bacteria
GK020_RS04680	COG2321	neutral zinc metallopeptidase
GK020_RS04690	COG0589	response to stress
GK020_RS04695	COG0110	maltose O-acetyltransferase activity
GK020_RS04725	COG0505	Belongs to the CarA family
GK020_RS04740	COG1534	Rna-binding protein
GK020_RS04745	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GK020_RS04750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GK020_RS04765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GK020_RS04800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GK020_RS04820	COG1597	lipid kinase activity
GK020_RS04845	COG0584	glycerophosphoryl diester phosphodiesterase
GK020_RS04855	COG2239	Acts as a magnesium transporter
GK020_RS04865	COG0501	Belongs to the peptidase M48B family
GK020_RS04870	COG1196	nuclear chromosome segregation
GK020_RS04870	COG0741	lytic transglycosylase activity
GK020_RS04870	COG0739	heme binding
GK020_RS04875	COG0037	tRNA processing
GK020_RS04885	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GK020_RS04890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GK020_RS04935	COG2184	nucleotidyltransferase activity
GK020_RS04945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GK020_RS04990	COG1840	ABC-type Fe3 transport system, periplasmic component
GK020_RS04995	COG3842	ATPase activity
GK020_RS05000	COG1741	Belongs to the pirin family
GK020_RS05015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GK020_RS05020	COG3739	integral membrane protein
GK020_RS05035	COG3706	GGDEF domain
GK020_RS05045	COG0302	gtp cyclohydrolase
GK020_RS05065	COG0512	Glutamine amidotransferase of anthranilate synthase
GK020_RS05070	COG0174	glutamine synthetase
GK020_RS05080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GK020_RS05090	COG0583	DNA-binding transcription factor activity
GK020_RS05125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GK020_RS05130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GK020_RS05150	COG1115	amino acid carrier protein
GK020_RS05155	COG1113	amino acid transport
GK020_RS05165	COG0019	diaminopimelate decarboxylase activity
GK020_RS05180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GK020_RS05190	COG1522	sequence-specific DNA binding
GK020_RS05195	COG1280	lysine exporter protein (LysE YggA)
GK020_RS05235	COG1671	Belongs to the UPF0178 family
GK020_RS05250	COG4591	ABC-type transport system involved in lipoprotein release permease component
GK020_RS05255	COG1136	(ABC) transporter
GK020_RS05260	COG0658	competence protein
GK020_RS05260	COG2333	competence protein COMEC
GK020_RS05285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GK020_RS05290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GK020_RS05295	COG0628	permease
GK020_RS05300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GK020_RS05330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GK020_RS05350	COG0823	Involved in the tonB-independent uptake of proteins
GK020_RS05370	COG0824	Thioesterase
GK020_RS05380	COG2255	four-way junction helicase activity
GK020_RS05400	COG0047	phosphoribosylformylglycinamidine synthase activity
GK020_RS05400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GK020_RS05415	COG0778	Nitroreductase
GK020_RS05420	COG1024	Enoyl-CoA hydratase
GK020_RS05425	COG1056	cytidyltransferase-related domain
GK020_RS05425	COG1051	belongs to the nudix hydrolase family
GK020_RS05430	COG2353	YceI-like domain
GK020_RS05435	COG0583	DNA-binding transcription factor activity
GK020_RS05445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GK020_RS05455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GK020_RS05460	COG0602	queuosine metabolic process
GK020_RS05480	COG0583	DNA-binding transcription factor activity
GK020_RS05485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GK020_RS05490	COG4208	sulfate ABC transporter
GK020_RS05505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GK020_RS05515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GK020_RS05530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GK020_RS05540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GK020_RS05555	COG0681	Belongs to the peptidase S26 family
GK020_RS05565	COG0571	ribonuclease III activity
GK020_RS05570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GK020_RS05580	COG1381	Involved in DNA repair and RecF pathway recombination
GK020_RS05585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GK020_RS05615	COG0436	Aminotransferase
GK020_RS05625	COG3706	GGDEF domain
GK020_RS05635	COG0556	nucleotide-excision repair
GK020_RS05665	COG0702	epimerase
GK020_RS05670	COG1733	regulation of RNA biosynthetic process
GK020_RS05685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GK020_RS05695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GK020_RS05700	COG0076	glutamate decarboxylase activity
GK020_RS05710	COG0573	inorganic phosphate transmembrane transporter activity
GK020_RS05720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GK020_RS05725	COG0616	signal peptide processing
GK020_RS05760	COG2963	transposase activity
GK020_RS05770	COG4372	Transposase
GK020_RS05775	COG1280	lysine exporter protein (LysE YggA)
GK020_RS05780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GK020_RS05785	COG1686	Belongs to the peptidase S11 family
GK020_RS05800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GK020_RS05810	COG0583	DNA-binding transcription factor activity
GK020_RS05815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GK020_RS05820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GK020_RS05825	COG1067	ATP-dependent peptidase activity
GK020_RS05860	COG1509	lysine 2,3-aminomutase activity
GK020_RS05865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GK020_RS05875	COG2879	small protein
GK020_RS05880	COG0714	Associated with various cellular activities
GK020_RS05915	COG2252	PERMEase
GK020_RS05920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GK020_RS05930	COG1215	transferase activity, transferring glycosyl groups
GK020_RS05940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GK020_RS05950	COG0527	aspartate kinase activity
GK020_RS05960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GK020_RS05975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GK020_RS05980	COG0501	Belongs to the peptidase M48B family
GK020_RS05995	COG0667	Aldo Keto reductase
GK020_RS06010	COG1765	OsmC-like protein
GK020_RS06030	COG0540	Belongs to the ATCase OTCase family
GK020_RS06045	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GK020_RS06060	COG4770	biotin carboxylase activity
GK020_RS06065	COG1024	Enoyl-CoA hydratase
GK020_RS06070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GK020_RS06075	COG1960	acyl-CoA dehydrogenase activity
GK020_RS06080	COG1309	transcriptional regulator
GK020_RS06085	COG0318	PFAM AMP-dependent synthetase and ligase
GK020_RS06105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GK020_RS06115	COG0659	secondary active sulfate transmembrane transporter activity
GK020_RS06135	COG2363	Small membrane protein
GK020_RS06155	COG0513	Belongs to the DEAD box helicase family
GK020_RS06220	COG4783	chaperone-mediated protein folding
GK020_RS06235	COG1610	YqeY-like protein
GK020_RS06270	COG0515	serine threonine protein kinase
GK020_RS06270	COG2815	serine threonine protein kinase
GK020_RS06310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GK020_RS06310	COG2755	lipolytic protein G-D-S-L family
GK020_RS06315	COG0436	Aminotransferase
GK020_RS06320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GK020_RS06325	COG0386	Belongs to the glutathione peroxidase family
GK020_RS06335	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GK020_RS06350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GK020_RS06360	COG0012	GTP binding
GK020_RS06385	COG0204	Acyl-transferase
GK020_RS06395	COG0582	viral genome integration into host DNA
GK020_RS06430	COG3293	Transposase
GK020_RS06455	COG3293	Transposase
GK020_RS06505	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS06510	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GK020_RS06520	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS06595	COG3293	Transposase
GK020_RS06610	COG0783	Belongs to the Dps family
GK020_RS06635	COG2030	dehydratase
GK020_RS06635	COG1012	belongs to the aldehyde dehydrogenase family
GK020_RS06640	COG3396	Phenylacetate-CoA oxygenase
GK020_RS06645	COG3460	Phenylacetate-CoA oxygenase
GK020_RS06650	COG3396	Phenylacetate-CoA oxygenase
GK020_RS06655	COG2151	metal-sulfur cluster biosynthetic enzyme
GK020_RS06660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GK020_RS06670	COG1024	Enoyl-CoA hydratase
GK020_RS06675	COG1250	3-hydroxyacyl-CoA dehydrogenase
GK020_RS06680	COG0183	Belongs to the thiolase family
GK020_RS06685	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GK020_RS06690	COG3327	negative regulation of DNA-templated transcription, initiation
GK020_RS06700	COG0318	PFAM AMP-dependent synthetase and ligase
GK020_RS06720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GK020_RS06725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GK020_RS06725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GK020_RS06730	COG1254	Belongs to the acylphosphatase family
GK020_RS06770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GK020_RS06775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GK020_RS06785	COG2353	YceI-like domain
GK020_RS06790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GK020_RS06790	COG0519	Catalyzes the synthesis of GMP from XMP
GK020_RS06810	COG1454	alcohol dehydrogenase
GK020_RS06820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GK020_RS06825	COG0583	DNA-binding transcription factor activity
GK020_RS06835	COG2707	UPF0756 membrane protein
GK020_RS06860	COG0802	atpase or kinase
GK020_RS06865	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GK020_RS06875	COG1923	regulation of RNA biosynthetic process
GK020_RS06880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GK020_RS06890	COG3178	'Phosphotransferase
GK020_RS06895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GK020_RS06905	COG1192	Involved in chromosome partitioning
GK020_RS06910	COG1475	DNA binding
GK020_RS06915	COG0811	peptide transport
GK020_RS06925	COG1132	(ABC) transporter
GK020_RS06930	COG1663	tetraacyldisaccharide 4'-kinase activity
GK020_RS06950	COG0084	hydrolase, TatD family'
GK020_RS06985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GK020_RS07015	COG0776	regulation of translation
GK020_RS07030	COG2431	L-lysine efflux transmembrane transporter activity
GK020_RS07045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GK020_RS07050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GK020_RS07070	COG1253	flavin adenine dinucleotide binding
GK020_RS07100	COG0583	DNA-binding transcription factor activity
GK020_RS07110	COG2204	response regulator
GK020_RS07115	COG3852	Histidine kinase
GK020_RS07130	COG0233	cytoplasmic translational termination
GK020_RS07135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GK020_RS07140	COG0575	Belongs to the CDS family
GK020_RS07155	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GK020_RS07165	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GK020_RS07175	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GK020_RS07205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GK020_RS07210	COG0730	response to heat
GK020_RS07215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GK020_RS07220	COG2207	Transcriptional regulator
GK020_RS07225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GK020_RS07245	COG1960	acyl-CoA dehydrogenase activity
GK020_RS07250	COG1960	acyl-CoA dehydrogenase activity
GK020_RS07295	COG1585	Membrane protein implicated in regulation of membrane protease activity
GK020_RS07305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GK020_RS07325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GK020_RS07330	COG0569	domain protein
GK020_RS07340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GK020_RS07360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GK020_RS07365	COG0542	response to heat
GK020_RS07405	COG0372	Belongs to the citrate synthase family
GK020_RS07415	COG1546	Belongs to the CinA family
GK020_RS07415	COG1058	Belongs to the CinA family
GK020_RS07445	COG3038	cytochrome b561
GK020_RS07450	COG2814	Major facilitator Superfamily
GK020_RS07465	COG0439	Biotin carboxylase
GK020_RS07470	COG0511	ligase activity, forming carbon-carbon bonds
GK020_RS07485	COG4372	Transposase
GK020_RS07495	COG2963	transposase activity
GK020_RS07510	COG4372	Transposase
GK020_RS07540	COG0596	Alpha beta hydrolase
GK020_RS07580	COG2801	Transposase and inactivated derivatives
GK020_RS07590	COG0730	response to heat
GK020_RS07595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GK020_RS07600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GK020_RS07615	COG2026	Addiction module toxin, RelE StbE family
GK020_RS07635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GK020_RS07645	COG0745	RESPONSE REGULATOR receiver
GK020_RS07660	COG1012	belongs to the aldehyde dehydrogenase family
GK020_RS07665	COG1309	transcriptional regulator
GK020_RS07670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GK020_RS07715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GK020_RS07730	COG0515	serine threonine protein kinase
GK020_RS07745	COG2116	formate transmembrane transporter activity
GK020_RS07750	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GK020_RS07760	COG2223	nitrite transmembrane transporter activity
GK020_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
GK020_RS07800	COG2814	Major facilitator Superfamily
GK020_RS07805	COG0583	DNA-binding transcription factor activity
GK020_RS07810	COG4948	Mandelate Racemase Muconate Lactonizing
GK020_RS07815	COG4829	muconolactone delta-isomerase
GK020_RS07825	COG4638	Rieske (2fe-2S)
GK020_RS07830	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GK020_RS07835	COG0543	2 iron, 2 sulfur cluster binding
GK020_RS07835	COG0633	Ferredoxin
GK020_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
GK020_RS07845	COG3135	benzoate transporter
GK020_RS07850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GK020_RS07855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GK020_RS07860	COG0183	Belongs to the thiolase family
GK020_RS07865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GK020_RS07885	COG0583	DNA-binding transcription factor activity
GK020_RS07890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GK020_RS07895	COG4149	molybdate abc transporter
GK020_RS07905	COG0303	'Molybdopterin
GK020_RS07910	COG0521	Mo-molybdopterin cofactor biosynthetic process
GK020_RS07910	COG0315	cyclic pyranopterin monophosphate synthase activity
GK020_RS07925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GK020_RS07935	COG0243	molybdopterin cofactor binding
GK020_RS07940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GK020_RS07945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GK020_RS07945	COG2146	nitrite reductase [NAD(P)H] activity
GK020_RS07950	COG2223	nitrite transmembrane transporter activity
GK020_RS07960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GK020_RS07960	COG1116	anion transmembrane transporter activity
GK020_RS07965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GK020_RS07970	COG2937	Belongs to the GPAT DAPAT family
GK020_RS07975	COG0640	Transcriptional regulator
GK020_RS07995	COG3122	Protein conserved in bacteria
GK020_RS08000	COG0668	transmembrane transport
GK020_RS08010	COG1132	(ABC) transporter
GK020_RS08030	COG2814	Major facilitator Superfamily
GK020_RS08040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GK020_RS08055	COG1113	amino acid transport
GK020_RS08060	COG1448	Aminotransferase
GK020_RS08070	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GK020_RS08075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GK020_RS08125	COG1525	nuclease
GK020_RS08135	COG1294	oxidase, subunit
GK020_RS08140	COG1271	oxidase subunit
GK020_RS08150	COG2814	Major facilitator Superfamily
GK020_RS08155	COG2207	Transcriptional regulator
GK020_RS08160	COG1960	acyl-CoA dehydrogenase activity
GK020_RS08175	COG4372	Transposase
GK020_RS08185	COG2963	transposase activity
GK020_RS08215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GK020_RS08395	COG5377	YqaJ viral recombinase family
GK020_RS08435	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GK020_RS08455	COG0583	DNA-binding transcription factor activity
GK020_RS08460	COG1051	belongs to the nudix hydrolase family
GK020_RS08465	COG2801	Transposase and inactivated derivatives
GK020_RS08475	COG1346	cytolysis
GK020_RS08485	COG1283	sodium-dependent phosphate transmembrane transporter activity
GK020_RS08500	COG0693	protein deglycase activity
GK020_RS08555	COG0552	protein localization to endoplasmic reticulum
GK020_RS08560	COG0612	Peptidase, M16
GK020_RS08590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GK020_RS08590	COG0517	IMP dehydrogenase activity
GK020_RS08590	COG0617	tRNA 3'-terminal CCA addition
GK020_RS08605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GK020_RS08625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GK020_RS08680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GK020_RS08710	COG0822	iron-sulfur transferase activity
GK020_RS08715	COG0316	Belongs to the HesB IscA family
GK020_RS08745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GK020_RS08760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GK020_RS08765	COG0702	epimerase
GK020_RS08770	COG0268	Binds directly to 16S ribosomal RNA
GK020_RS08785	COG1011	Hydrolase
GK020_RS08790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GK020_RS08800	COG2137	regulation of response to DNA damage stimulus
GK020_RS08815	COG0772	Belongs to the SEDS family
GK020_RS08830	COG0148	phosphopyruvate hydratase activity
GK020_RS08865	COG1902	pentaerythritol trinitrate reductase activity
GK020_RS08865	COG0446	pyridine nucleotide-disulphide oxidoreductase
GK020_RS08875	COG0596	Alpha beta hydrolase
GK020_RS08880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GK020_RS08885	COG2814	Major facilitator Superfamily
GK020_RS08890	COG1960	acyl-CoA dehydrogenase activity
GK020_RS08895	COG0583	DNA-binding transcription factor activity
GK020_RS08900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GK020_RS08905	COG1027	Aspartate ammonia-lyase
GK020_RS08910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GK020_RS08920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GK020_RS08920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GK020_RS08920	COG0506	proline dehydrogenase activity
GK020_RS08940	COG3698	Phosphodiester glycosidase
GK020_RS08980	COG0697	spore germination
GK020_RS09005	COG0424	maF-like protein
GK020_RS09010	COG2850	peptidyl-arginine hydroxylation
GK020_RS09015	COG4585	Histidine kinase
GK020_RS09025	COG0069	glutamate synthase activity
GK020_RS09045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GK020_RS09050	COG1454	alcohol dehydrogenase
GK020_RS09055	COG0824	Thioesterase
GK020_RS09070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GK020_RS09075	COG2030	dehydratase
GK020_RS09085	COG0183	Belongs to the thiolase family
GK020_RS09100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GK020_RS09110	COG3135	benzoate transporter
GK020_RS09120	COG0589	response to stress
GK020_RS09125	COG0589	response to stress
GK020_RS09135	COG0308	aminopeptidase N
GK020_RS09200	COG4372	Transposase
GK020_RS09210	COG2963	transposase activity
GK020_RS09235	COG3772	lysozyme
GK020_RS09310	COG3561	AntA/AntB antirepressor
GK020_RS09325	COG4387	Mu-like prophage protein GP36
GK020_RS09360	COG2369	cell adhesion
GK020_RS09365	COG3567	Phage-associated protein, HI1409 family
GK020_RS09370	COG5410	chromosome segregation
GK020_RS09425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GK020_RS09445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GK020_RS09545	COG0477	Major facilitator Superfamily
GK020_RS09560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GK020_RS09570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GK020_RS09580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GK020_RS09585	COG1960	acyl-CoA dehydrogenase activity
GK020_RS09605	COG3781	membrane
GK020_RS09615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GK020_RS09630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GK020_RS09660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GK020_RS09665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GK020_RS09670	COG1845	cytochrome c oxidase, subunit III
GK020_RS09675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GK020_RS09685	COG0360	Binds together with S18 to 16S ribosomal RNA
GK020_RS09690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GK020_RS09705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GK020_RS09720	COG1305	Transglutaminase-like
GK020_RS09730	COG2308	Evidence 4 Homologs of previously reported genes of
GK020_RS09770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GK020_RS09775	COG0138	bifunctional purine biosynthesis protein purh
GK020_RS09800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GK020_RS09805	COG2011	ABC-type metal ion transport system permease component
GK020_RS09835	COG1454	alcohol dehydrogenase
GK020_RS09850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GK020_RS09860	COG4122	O-methyltransferase activity
GK020_RS09885	COG2274	protein secretion by the type I secretion system
GK020_RS09895	COG1137	ATPase activity
GK020_RS09900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GK020_RS09910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GK020_RS09915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GK020_RS09915	COG0517	IMP dehydrogenase activity
GK020_RS09940	COG1643	Atp-dependent helicase
GK020_RS09970	COG3634	alkyl hydroperoxide reductase activity
GK020_RS09985	COG2391	methyltransferase activity
GK020_RS10010	COG2070	2-Nitropropane dioxygenase
GK020_RS10020	COG0675	Transposase, IS605 OrfB family
GK020_RS10030	COG1278	Cold shock
GK020_RS10100	COG1309	transcriptional regulator
GK020_RS10105	COG0596	Alpha beta hydrolase
GK020_RS10145	COG0352	thiamine-phosphate diphosphorylase activity
GK020_RS10180	COG0612	Peptidase, M16
GK020_RS10190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GK020_RS10200	COG0739	heme binding
GK020_RS10210	COG1187	pseudouridine synthase activity
GK020_RS10225	COG1686	Belongs to the peptidase S11 family
GK020_RS10230	COG1252	NADH dehydrogenase
GK020_RS10235	COG1047	Peptidyl-prolyl cis-trans
GK020_RS10240	COG0415	Belongs to the DNA photolyase family
GK020_RS10260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GK020_RS10265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GK020_RS10275	COG0693	protein deglycase activity
GK020_RS10280	COG1960	acyl-CoA dehydrogenase activity
GK020_RS10285	COG1301	dicarboxylic acid transport
GK020_RS10300	COG3139	Protein of unknown function (DUF1315)
GK020_RS10305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GK020_RS10310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GK020_RS10345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GK020_RS10355	COG1720	tRNA m6t6A37 methyltransferase activity
GK020_RS10370	COG0789	Transcriptional regulator
GK020_RS10375	COG0431	NADPH-dependent FMN reductase
GK020_RS10380	COG0798	PFAM Bile acid sodium symporter
GK020_RS10390	COG0640	Transcriptional regulator
GK020_RS10400	COG0826	peptidase U32
GK020_RS10405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GK020_RS10410	COG3634	alkyl hydroperoxide reductase activity
GK020_RS10430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GK020_RS10485	COG1131	(ABC) transporter
GK020_RS10490	COG0842	Transport permease protein
GK020_RS10505	COG2951	lytic endotransglycosylase activity
GK020_RS10530	COG0052	Belongs to the universal ribosomal protein uS2 family
GK020_RS10550	COG2175	clavaminate synthase activity
GK020_RS10560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GK020_RS10570	COG1960	acyl-CoA dehydrogenase activity
GK020_RS10585	COG1473	amidohydrolase
GK020_RS10600	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS10610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GK020_RS10615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GK020_RS10620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GK020_RS10640	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GK020_RS10645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GK020_RS10700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GK020_RS10705	COG4372	Transposase
GK020_RS10725	COG1902	pentaerythritol trinitrate reductase activity
GK020_RS10725	COG0446	pyridine nucleotide-disulphide oxidoreductase
GK020_RS10740	COG4251	negative regulation of phosphorylation
GK020_RS10740	COG3706	GGDEF domain
GK020_RS10740	COG5001	Diguanylate cyclase
GK020_RS10740	COG2203	Gaf domain
GK020_RS10745	COG0418	dihydroorotase activity
GK020_RS10750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GK020_RS10770	COG0833	amino acid
GK020_RS10795	COG4172	Belongs to the ABC transporter superfamily
GK020_RS10800	COG4239	(ABC) transporter, permease
GK020_RS10805	COG4174	ABC transporter (Permease)
GK020_RS10810	COG4166	transmembrane transport
GK020_RS10815	COG0741	lytic transglycosylase activity
GK020_RS10815	COG1388	LysM domain
GK020_RS10830	COG2816	NAD+ diphosphatase activity
GK020_RS10870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GK020_RS10875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GK020_RS10880	COG0006	proline dipeptidase activity
GK020_RS10885	COG3079	Belongs to the UPF0149 family
GK020_RS10905	COG3706	GGDEF domain
GK020_RS10920	COG0277	FAD linked oxidase domain protein
GK020_RS10930	COG2186	Transcriptional regulator
GK020_RS10955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GK020_RS10970	COG2234	aminopeptidase activity
GK020_RS10980	COG3384	dioxygenase
GK020_RS10990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GK020_RS10995	COG2878	Part of a membrane complex involved in electron transport
GK020_RS11000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GK020_RS11025	COG0768	penicillin binding
GK020_RS11030	COG0742	ribosomal rna small subunit methyltransferase
GK020_RS11045	COG0830	nickel cation binding
GK020_RS11065	COG0804	urea catabolic process
GK020_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
GK020_RS11100	COG3015	lipoprotein NlpE involved in copper resistance
GK020_RS11120	COG1253	flavin adenine dinucleotide binding
GK020_RS11140	COG3118	belongs to the thioredoxin family
GK020_RS11170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GK020_RS11175	COG1773	rubredoxin
GK020_RS11180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GK020_RS11190	COG0583	DNA-binding transcription factor activity
GK020_RS11200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GK020_RS11210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GK020_RS11215	COG4181	ATPase activity
GK020_RS11260	COG0306	phosphate transporter
GK020_RS11280	COG2376	Dihydroxyacetone kinase
GK020_RS11285	COG2066	Belongs to the glutaminase family
GK020_RS11325	COG2203	Gaf domain
GK020_RS11325	COG2199	diguanylate cyclase activity
GK020_RS11335	COG4681	YaeQ
GK020_RS11340	COG0523	cobalamin synthesis protein
GK020_RS11365	COG1607	acyl-coa hydrolase
GK020_RS11375	COG1752	Esterase of the alpha-beta hydrolase superfamily
GK020_RS11380	COG2059	Chromate
GK020_RS11385	COG1115	amino acid carrier protein
GK020_RS11390	COG0786	glutamate:sodium symporter activity
GK020_RS11405	COG2814	Major facilitator Superfamily
GK020_RS11410	COG1289	transmembrane transporter activity
GK020_RS11420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GK020_RS11475	COG1376	ErfK ybiS ycfS ynhG family protein
GK020_RS11480	COG2832	Protein of unknown function (DUF454)
GK020_RS11490	COG5510	response to toxic substance
GK020_RS11505	COG2198	Histidine kinase
GK020_RS11505	COG0643	Histidine kinase
GK020_RS11505	COG0784	Response regulator, receiver
GK020_RS11510	COG0840	transmembrane signaling receptor activity
GK020_RS11545	COG0442	prolyl-tRNA aminoacylation
GK020_RS11580	COG0489	protein tyrosine kinase activity
GK020_RS11585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GK020_RS11585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GK020_RS11605	COG3328	transposase activity
GK020_RS11615	COG0004	ammonium transporteR
GK020_RS11630	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GK020_RS11645	COG2081	HI0933 family
GK020_RS11655	COG0668	transmembrane transport
GK020_RS11680	COG0583	DNA-binding transcription factor activity
GK020_RS11685	COG1278	Cold shock
GK020_RS11700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GK020_RS11705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GK020_RS11710	COG0713	ATP synthesis coupled electron transport
GK020_RS11715	COG0839	Belongs to the complex I subunit 6 family
GK020_RS11720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GK020_RS11725	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GK020_RS11735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GK020_RS11755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GK020_RS11765	COG0142	geranyltranstransferase activity
GK020_RS11770	COG2828	Protein conserved in bacteria
GK020_RS11775	COG1113	amino acid transport
GK020_RS11795	COG0625	glutathione transferase activity
GK020_RS11835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GK020_RS11840	COG1530	ribonuclease E activity
GK020_RS11845	COG0424	maF-like protein
GK020_RS11850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GK020_RS11855	COG1792	Involved in formation and maintenance of cell shape
GK020_RS11860	COG1077	Cell shape determining protein MreB Mrl
GK020_RS11865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GK020_RS11870	COG0154	amidase activity
GK020_RS11875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GK020_RS11890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GK020_RS11905	COG0354	folic acid binding
GK020_RS11915	COG1953	Uracil, thiamine, allantoin
GK020_RS11950	COG0363	glucosamine-6-phosphate deaminase activity
GK020_RS11960	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GK020_RS11965	COG1877	trehalose-phosphatase activity
GK020_RS11975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GK020_RS11980	COG1970	mechanosensitive ion channel activity
GK020_RS11985	COG1217	gtp-binding protein TYPA
GK020_RS11990	COG2233	PERMEase
GK020_RS12000	COG0833	amino acid
GK020_RS12020	COG0183	Belongs to the thiolase family
GK020_RS12035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GK020_RS12040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GK020_RS12045	COG2207	Transcriptional regulator
GK020_RS12050	COG0183	Belongs to the thiolase family
GK020_RS12055	COG1250	3-hydroxyacyl-CoA dehydrogenase
GK020_RS12055	COG1024	Enoyl-CoA hydratase
GK020_RS12075	COG1272	protein, Hemolysin III
GK020_RS12080	COG0477	Major facilitator Superfamily
GK020_RS12090	COG1408	metallophosphoesterase
GK020_RS12095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GK020_RS12105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GK020_RS12135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GK020_RS12140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GK020_RS12145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GK020_RS12155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GK020_RS12160	COG0625	glutathione transferase activity
GK020_RS12165	COG2969	positive regulation of protein catabolic process
GK020_RS12210	COG2885	chlorophyll binding
GK020_RS12235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GK020_RS12240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GK020_RS12260	COG0450	alkyl hydroperoxide reductase
GK020_RS12275	COG0285	dihydrofolate synthase activity
GK020_RS12280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GK020_RS12320	COG3328	transposase activity
GK020_RS12335	COG4206	TonB-dependent receptor
GK020_RS12340	COG2096	Adenosyltransferase
GK020_RS12360	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GK020_RS12365	COG2315	Protein conserved in bacteria
GK020_RS12375	COG0745	RESPONSE REGULATOR receiver
GK020_RS12380	COG2205	protein histidine kinase activity
GK020_RS12390	COG1960	acyl-CoA dehydrogenase activity
GK020_RS12395	COG1960	acyl-CoA dehydrogenase activity
GK020_RS12435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GK020_RS12465	COG0463	Glycosyl transferase, family 2
GK020_RS12485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GK020_RS12490	COG5002	protein histidine kinase activity
GK020_RS12510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GK020_RS12520	COG1704	LemA family
GK020_RS12525	COG2203	Gaf domain
GK020_RS12525	COG3706	GGDEF domain
GK020_RS12525	COG4251	negative regulation of phosphorylation
GK020_RS12525	COG5001	Diguanylate cyclase
GK020_RS12535	COG1862	Preprotein translocase
GK020_RS12555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GK020_RS12570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GK020_RS12575	COG2205	protein histidine kinase activity
GK020_RS12575	COG5002	protein histidine kinase activity
GK020_RS12575	COG0784	Response regulator, receiver
GK020_RS12580	COG1024	Enoyl-CoA hydratase
GK020_RS12585	COG2084	Dehydrogenase
GK020_RS12590	COG3622	Belongs to the hyi family
GK020_RS12600	COG3385	transposase activity
GK020_RS12620	COG0697	spore germination
GK020_RS12625	COG2814	Major facilitator Superfamily
GK020_RS12645	COG1546	Belongs to the CinA family
GK020_RS12645	COG1058	Belongs to the CinA family
GK020_RS12680	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GK020_RS12695	COG0732	type I restriction modification DNA specificity domain
GK020_RS12705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GK020_RS12765	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS12790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GK020_RS12810	COG4372	Transposase
GK020_RS12820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GK020_RS12825	COG0084	hydrolase, TatD family'
GK020_RS12840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GK020_RS12870	COG2862	Uncharacterized protein family, UPF0114
GK020_RS12885	COG4372	Transposase
GK020_RS12895	COG2963	transposase activity
GK020_RS12910	COG3328	transposase activity
GK020_RS12940	COG0745	RESPONSE REGULATOR receiver
GK020_RS12945	COG0642	Histidine kinase
GK020_RS12950	COG4106	trans-aconitate 2-methyltransferase activity
GK020_RS12960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GK020_RS12995	COG3046	protein related to deoxyribodipyrimidine photolyase
GK020_RS13015	COG4774	siderophore transport
GK020_RS13025	COG0793	Belongs to the peptidase S41A family
GK020_RS13055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GK020_RS13060	COG0857	belongs to the CobB CobQ family
GK020_RS13060	COG0280	phosphate acetyltransferase
GK020_RS13085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GK020_RS13085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GK020_RS13100	COG0740	serine-type endopeptidase activity
GK020_RS13125	COG4774	siderophore transport
GK020_RS13130	COG3128	pkhd-type hydroxylase
GK020_RS13140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GK020_RS13145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GK020_RS13150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GK020_RS13150	COG2813	Specifically methylates the guanine in position
GK020_RS13210	COG3040	lipid binding
GK020_RS13220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GK020_RS13230	COG4372	Transposase
GK020_RS13240	COG2963	transposase activity
GK020_RS13260	COG2963	transposase activity
GK020_RS13270	COG4372	Transposase
GK020_RS13325	COG0179	Fumarylacetoacetate (FAA) hydrolase
GK020_RS13360	COG0557	exoribonuclease II activity
GK020_RS13365	COG0339	signal peptide processing
GK020_RS13370	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GK020_RS13385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GK020_RS13405	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GK020_RS13410	COG1960	acyl-CoA dehydrogenase activity
GK020_RS13415	COG2072	flavoprotein involved in K transport
GK020_RS13425	COG0202	RNA polymerase activity
GK020_RS13430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GK020_RS13465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GK020_RS13475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GK020_RS13480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GK020_RS13515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GK020_RS13545	COG0088	Forms part of the polypeptide exit tunnel
GK020_RS13570	COG0433	COG0433 Predicted ATPase
GK020_RS13580	COG1959	2 iron, 2 sulfur cluster binding
GK020_RS13590	COG2801	Transposase and inactivated derivatives
GK020_RS13610	COG2963	transposase activity
GK020_RS13620	COG4372	Transposase
GK020_RS13630	COG1301	dicarboxylic acid transport
GK020_RS13635	COG1946	Acyl-CoA thioesterase
GK020_RS13640	COG2937	Belongs to the GPAT DAPAT family
GK020_RS13650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GK020_RS13655	COG1040	competence protein
GK020_RS13670	COG0598	Magnesium transport protein CorA
GK020_RS13680	COG2854	intermembrane phospholipid transfer
GK020_RS13685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GK020_RS13690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GK020_RS13695	COG1127	ABC transporter
GK020_RS13720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GK020_RS13725	COG0408	coproporphyrinogen oxidase activity
GK020_RS13740	COG1960	acyl-CoA dehydrogenase activity
GK020_RS13745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GK020_RS13755	COG0534	Mate efflux family protein
GK020_RS13760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GK020_RS13765	COG0254	rRNA binding
GK020_RS13770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GK020_RS13790	COG2226	methyltransferase
GK020_RS13805	COG1192	Involved in chromosome partitioning
GK020_RS13810	COG0628	permease
GK020_RS13820	COG2814	Major facilitator Superfamily
GK020_RS13835	COG0277	FAD linked oxidase domain protein
GK020_RS13840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GK020_RS13865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GK020_RS13870	COG5380	lipid catabolic process
GK020_RS13880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GK020_RS13890	COG0335	large ribosomal subunit rRNA binding
GK020_RS13900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GK020_RS13905	COG0228	four-way junction DNA binding
GK020_RS13940	COG4969	Belongs to the N-Me-Phe pilin family
GK020_RS13950	COG0194	GDP metabolic process
GK020_RS13955	COG1758	RNA polymerase activity
GK020_RS13960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GK020_RS13980	COG3307	-O-antigen
GK020_RS13990	COG4969	Belongs to the N-Me-Phe pilin family
GK020_RS14000	COG2161	toxin-antitoxin pair type II binding
GK020_RS14085	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GK020_RS14090	COG1704	LemA family
GK020_RS14100	COG0493	'glutamate synthase
GK020_RS14105	COG0067	glutamate synthase
GK020_RS14105	COG0069	glutamate synthase activity
GK020_RS14105	COG0070	glutamate synthase
GK020_RS14155	COG3385	transposase activity
GK020_RS14160	COG2226	methyltransferase
GK020_RS14170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GK020_RS14175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GK020_RS14190	COG0275	rRNA processing
GK020_RS14195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GK020_RS14205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GK020_RS14225	COG0488	(ABC) transporter
GK020_RS14245	COG4221	oxidoreductase activity
GK020_RS14275	COG0427	acetyl-CoA hydrolase
GK020_RS14305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GK020_RS14325	COG0697	spore germination
GK020_RS14340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GK020_RS14380	COG3158	transport of potassium into the cell
GK020_RS14390	COG0582	viral genome integration into host DNA
GK020_RS14405	COG2223	nitrite transmembrane transporter activity
GK020_RS14430	COG4804	nuclease activity
GK020_RS14435	COG0732	type I restriction modification DNA specificity domain
GK020_RS14440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GK020_RS14470	COG2963	transposase activity
GK020_RS14505	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GK020_RS14535	COG2801	Transposase and inactivated derivatives
GK020_RS14545	COG3077	Addiction module antitoxin, RelB DinJ family
GK020_RS14550	COG2801	Transposase and inactivated derivatives
GK020_RS14565	COG2132	Multicopper oxidase
GK020_RS14580	COG4372	Transposase
GK020_RS14600	COG2963	transposase activity
GK020_RS14610	COG4372	Transposase
GK020_RS14615	COG2826	transposase and inactivated derivatives, IS30 family
GK020_RS14635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GK020_RS14735	COG2217	Heavy metal translocating P-type atpase
GK020_RS14740	COG3174	membrane
GK020_RS14745	COG2205	protein histidine kinase activity
GK020_RS14760	COG2132	Multicopper oxidase
GK020_RS14795	COG4372	Transposase
GK020_RS14860	COG0629	single-stranded DNA binding
GK020_RS14865	COG2814	Major facilitator Superfamily
GK020_RS14885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GK020_RS14890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GK020_RS14915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GK020_RS14935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GK020_RS14940	COG3162	membrane
GK020_RS14945	COG2205	protein histidine kinase activity
GK020_RS14945	COG0784	Response regulator, receiver
GK020_RS14960	COG0431	NADPH-dependent FMN reductase
GK020_RS14970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GK020_RS14975	COG0668	transmembrane transport
GK020_RS14980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GK020_RS14985	COG1519	Transferase
GK020_RS14990	COG1902	pentaerythritol trinitrate reductase activity
GK020_RS15015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GK020_RS15050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GK020_RS15050	COG0426	domain, Protein
GK020_RS15055	COG2119	membrane
GK020_RS15085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GK020_RS15095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GK020_RS15105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GK020_RS15110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GK020_RS15115	COG0189	ligase activity
GK020_RS15140	COG0708	Exodeoxyribonuclease III
GK020_RS15145	COG1393	Belongs to the ArsC family
GK020_RS15160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GK020_RS15165	COG3706	GGDEF domain
GK020_RS15170	COG0625	glutathione transferase activity
GK020_RS15210	COG1247	-acetyltransferase
GK020_RS15215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GK020_RS15220	COG4266	Belongs to the allantoicase family
GK020_RS15225	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GK020_RS15235	COG0471	metal ion transport
GK020_RS15275	COG3150	esterase
GK020_RS15285	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GK020_RS15290	COG2918	glutathione biosynthetic process
GK020_RS15305	COG2733	membrane
GK020_RS15310	COG0436	Aminotransferase
GK020_RS15315	COG0534	Mate efflux family protein
GK020_RS15360	COG0753	catalase activity
GK020_RS15380	COG0560	Phosphoserine phosphatase
GK020_RS15380	COG3830	Belongs to the UPF0237 family
GK020_RS15395	COG0385	Bile acid
GK020_RS15400	COG1335	isochorismatase
GK020_RS15405	COG2814	Major facilitator Superfamily
GK020_RS15410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GK020_RS15420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GK020_RS15425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GK020_RS15430	COG2983	Belongs to the UPF0260 family
GK020_RS15435	COG5487	UPF0391 membrane protein
GK020_RS15450	COG1194	a g-specific adenine glycosylase
GK020_RS15455	COG0739	heme binding
GK020_RS15465	COG2818	Glycosylase
GK020_RS15470	COG1064	alcohol dehydrogenase
GK020_RS15490	COG3023	N-Acetylmuramoyl-L-alanine amidase
GK020_RS15500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GK020_RS15505	COG1309	transcriptional regulator
GK020_RS15515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GK020_RS15520	COG0546	phosphoglycolate phosphatase activity
GK020_RS15525	COG1028	Short-chain dehydrogenase reductase Sdr
GK020_RS15550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GK020_RS15555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GK020_RS15560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GK020_RS15565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GK020_RS15570	COG1116	anion transmembrane transporter activity
GK020_RS15585	COG1309	transcriptional regulator
GK020_RS15595	COG0196	riboflavin kinase activity
GK020_RS15600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GK020_RS15605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GK020_RS15610	COG1047	Peptidyl-prolyl cis-trans
GK020_RS15620	COG2133	pyrroloquinoline quinone binding
GK020_RS15625	COG2814	Major facilitator Superfamily
GK020_RS15655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GK020_RS15665	COG0657	acetylesterase activity
GK020_RS15710	COG2951	lytic endotransglycosylase activity
GK020_RS15720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GK020_RS15740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GK020_RS15750	COG2388	GCN5-related N-acetyl-transferase
GK020_RS15760	COG0861	Integral membrane protein TerC family
GK020_RS15765	COG0402	S-adenosylhomocysteine deaminase activity
GK020_RS15775	COG0675	Transposase, IS605 OrfB family
GK020_RS15785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GK020_RS15790	COG1230	cation diffusion facilitator family transporter
GK020_RS15815	COG0706	membrane insertase activity
GK020_RS15820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GK020_RS15825	COG0594	ribonuclease P activity