locus-tag	class	description
GA646_RS00095	ENOG4105PGM	cation diffusion facilitator family transporter
GA646_RS00130	ENOG4105CBC	glutamate synthase
GA646_RS00135	ENOG4105M90	Glutamate synthase alpha subunit domain protein
GA646_RS00140	ENOG4105EYU	Glutamine amido-transferase
GA646_RS00150	ENOG4108IMY	Transcriptional regulator
GA646_RS00155	ENOG4105BZU	Histidine kinase
GA646_RS00160	ENOG4105BZU	Histidine kinase
GA646_RS00180	ENOG4105C0D	helicase
GA646_RS00185	ENOG4105E3B	Multicopper oxidase
GA646_RS00230	ENOG4105KT5	UmuD protein
GA646_RS00235	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GA646_RS00250	ENOG4105E3B	Multicopper oxidase
GA646_RS00265	ENOG4105GR3	Histidine kinase
GA646_RS00270	ENOG4107PU6	Membrane
GA646_RS00275	ENOG4105C59	p-type ATPase
GA646_RS00365	ENOG4105CHH	sulfate transporter
GA646_RS00375	ENOG4105H3G	oxidoreductase
GA646_RS00380	ENOG4105C3M	thioredoxin reductase
GA646_RS00385	ENOG4105CAU	Arsenical resistance protein, ArsH
GA646_RS00390	ENOG4105D6J	arsenicaL-resistance protein
GA646_RS00400	ENOG4105KBH	arsR family transcriptional regulator
GA646_RS00410	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GA646_RS00465	ENOG4108R0M	Aminoglycoside
GA646_RS00560	ENOG4105E4P	ATPase (AAA
GA646_RS00580	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GA646_RS00600	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GA646_RS00615	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GA646_RS00640	ENOG4108YZA	Nitrogen regulatory protein pii
GA646_RS00655	ENOG4105E3J	oxidoreductase
GA646_RS00675	ENOG4105WH1	Two component transcriptional regulator luxr family
GA646_RS00680	ENOG4105BZU	Histidine kinase
GA646_RS00685	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GA646_RS00690	ENOG4105FA0	parb-like partition protein
GA646_RS00695	ENOG4107QJE	Chromosome Partitioning Protein
GA646_RS00715	ENOG4108JUA	Transcriptional regulator
GA646_RS00750	ENOG4105H3G	oxidoreductase
GA646_RS00765	ENOG4105D9P	serine threonine protein kinase
GA646_RS00845	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GA646_RS00850	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GA646_RS00860	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GA646_RS00885	ENOG4105C5H	ABC transporter
GA646_RS00890	ENOG4108821	RND type efflux pump
GA646_RS00895	ENOG4108821	RND type efflux pump
GA646_RS00900	ENOG4108821	RND type efflux pump
GA646_RS00910	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GA646_RS00915	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GA646_RS00965	ENOG4105D2S	major facilitator superfamily
GA646_RS00980	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GA646_RS00985	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GA646_RS00990	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GA646_RS00995	ENOG4105DTN	riboflavin biosynthesis protein ribF
GA646_RS01005	ENOG4108R86	Transcriptional regulator
GA646_RS01010	ENOG4105D7V	transposase
GA646_RS01020	ENOG4108VM9	ABC, transporter
GA646_RS01025	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GA646_RS01030	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
GA646_RS01035	ENOG4105GVF	(ABC) transporter
GA646_RS01040	ENOG4105GVF	(ABC) transporter
GA646_RS01045	ENOG4107QZM	n-acetylglutamate synthase
GA646_RS01065	ENOG4105UBK	short-chain dehydrogenase reductase
GA646_RS01070	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GA646_RS01075	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GA646_RS01085	ENOG4105EJ2	Transcriptional regulator
GA646_RS01090	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GA646_RS01095	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GA646_RS01100	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GA646_RS01105	ENOG4105CJR	Integral membrane protein (MviN
GA646_RS01110	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GA646_RS01115	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GA646_RS01120	ENOG4105DQ4	alcohol dehydrogenase
GA646_RS01125	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GA646_RS01135	ENOG4105FAA	peptidase M23
GA646_RS01140	ENOG4105CEN	a g-specific adenine glycosylase
GA646_RS01160	ENOG4108ZZ3	UPF0260 protein
GA646_RS01165	ENOG4105D1H	recombination factor protein RarA
GA646_RS01170	ENOG4105C8V	SAICAR synthetase
GA646_RS01180	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GA646_RS01185	ENOG4108SC4	)-transporter
GA646_RS01190	ENOG4108RWI	nicotinamidase
GA646_RS01195	ENOG4105C09	Bile acid
GA646_RS01210	ENOG4105EAC	phosphoserine phosphatase
GA646_RS01245	ENOG4105KHC	sulfurtransferase
GA646_RS01255	ENOG4105BZU	Histidine kinase
GA646_RS01260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GA646_RS01275	ENOG4105E2B	Taurine dioxygenase
GA646_RS01280	ENOG4107QJQ	Mate efflux family protein
GA646_RS01285	ENOG4105CHM	Aminotransferase
GA646_RS01290	ENOG4106BRA	Membrane
GA646_RS01305	ENOG4105D9M	gamma-glutamylcysteine synthetase
GA646_RS01310	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GA646_RS01320	ENOG4105IPS	esterase
GA646_RS01325	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GA646_RS01330	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
GA646_RS01335	ENOG4105C32	Amino acid ABC transporter (Permease)
GA646_RS01345	ENOG4105C0Z	ABC transporter
GA646_RS01350	ENOG4108IV0	ABC, transporter
GA646_RS01355	ENOG4105C8P	)-transporter
GA646_RS01370	ENOG4108Z2U	ureidoglycolate hydrolase
GA646_RS01375	ENOG4105DHG	Allantoate amidinohydrolase
GA646_RS01380	ENOG41061H0	Monooxygenase
GA646_RS01385	ENOG4108Z7F	N-acetyltransferase
GA646_RS01415	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS01420	ENOG4105D7V	transposase
GA646_RS01435	ENOG4108K3A	Glutathione S-transferase
GA646_RS01440	ENOG4105BZU	Histidine kinase
GA646_RS01445	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GA646_RS01460	ENOG4105KUZ	arsenate reductase
GA646_RS01465	ENOG4105CGK	Exodeoxyribonuclease III
GA646_RS01485	ENOG4105D7Z	glutathione synthase
GA646_RS01490	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GA646_RS01495	ENOG4105DFU	Cell wall formation (By similarity)
GA646_RS01505	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GA646_RS01510	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GA646_RS01515	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GA646_RS01535	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GA646_RS01540	ENOG4107QSN	dihydrolipoamide acetyltransferase
GA646_RS01560	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS01565	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GA646_RS01580	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GA646_RS01590	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS01610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GA646_RS01615	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GA646_RS01625	ENOG4105D64	Mechanosensitive ion channel
GA646_RS01630	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GA646_RS01635	ENOG4107T8P	acyl-Coa dehydrogenase
GA646_RS01640	ENOG4108UZX	fmn reductase
GA646_RS01655	ENOG4105BZU	Histidine kinase
GA646_RS01660	ENOG41062QD	Membrane
GA646_RS01665	ENOG4107QN1	sodium solute
GA646_RS01685	ENOG4108J1Q	
GA646_RS01690	ENOG4105C94	Transporter
GA646_RS01700	ENOG4105BZU	Histidine kinase
GA646_RS01705	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GA646_RS01710	ENOG4105ETU	transcriptional activator (TenA
GA646_RS01720	ENOG4107RDB	Major Facilitator
GA646_RS01725	ENOG4108UUM	single-stranded DNA-binding protein
GA646_RS01730	ENOG4105D3R	alkyl hydroperoxide reductase
GA646_RS01735	ENOG4105EUB	pirin domain protein
GA646_RS01740	ENOG4105CVN	desaturase
GA646_RS01760	ENOG4108RS6	transposase
GA646_RS01875	ENOG4105DFP	Integrase
GA646_RS01885	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GA646_RS01925	ENOG4105CUV	Homoserine Kinase
GA646_RS01940	ENOG4108Q5Y	Membrane
GA646_RS01960	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GA646_RS01990	ENOG4105CYC	Transferase
GA646_RS01995	ENOG4105E0F	Histidine kinase
GA646_RS02000	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GA646_RS02025	ENOG4105PDP	Short chain dehydrogenase
GA646_RS02035	ENOG4105C5H	ABC transporter
GA646_RS02055	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GA646_RS02065	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GA646_RS02075	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GA646_RS02085	ENOG4105CJN	penicillin-binding protein
GA646_RS02090	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GA646_RS02095	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GA646_RS02105	ENOG4105DHI	Methyltransferase
GA646_RS02110	ENOG4108JQC	penicillin-binding protein 1A
GA646_RS02130	ENOG4108RS6	transposase
GA646_RS02170	ENOG4105CBC	glutamate synthase
GA646_RS02175	ENOG4105BZ8	glutamate synthase
GA646_RS02185	ENOG4108V0P	LemA family
GA646_RS02190	ENOG4105HA9	of methanol dehydrogenase type
GA646_RS02205	ENOG4108YSG	O-Antigen polymerase
GA646_RS02210	ENOG4108UQY	Iron-storage protein
GA646_RS02215	ENOG4105W53	bacterioferritin-associated ferredoxin
GA646_RS02220	ENOG4105KME	endoribonuclease L-psp
GA646_RS02225	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GA646_RS02230	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GA646_RS02235	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GA646_RS02275	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GA646_RS02285	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GA646_RS02290	ENOG4105K5M	30s ribosomal protein S16
GA646_RS02295	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GA646_RS02315	ENOG4107AQZ	Membrane
GA646_RS02320	ENOG4108JQ1	Dehydrogenase
GA646_RS02325	ENOG4105CQB	FAD linked oxidase domain protein
GA646_RS02335	ENOG4107QF7	multi-drug
GA646_RS02340	ENOG4105VCH	membrane
GA646_RS02345	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GA646_RS02350	ENOG4105IPI	Membrane
GA646_RS02355	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
GA646_RS02375	ENOG4108RS6	transposase
GA646_RS02380	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GA646_RS02405	ENOG4105WMR	Protein CrcB homolog
GA646_RS02410	ENOG4105NRA	50s ribosomal protein l31 type b
GA646_RS02420	ENOG4107QI1	Mate efflux family protein
GA646_RS02430	ENOG4105CSA	Coproporphyrinogen iii oxidase
GA646_RS02435	ENOG4105CSU	acyl-Coa dehydrogenase
GA646_RS02450	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GA646_RS02455	ENOG4105D4P	Coproporphyrinogen iii oxidase
GA646_RS02475	ENOG4105ECY	inositol monophosphatase
GA646_RS02480	ENOG4105C1J	atp-dependent rna helicase
GA646_RS02485	ENOG4105DHJ	ABC, transporter
GA646_RS02490	ENOG4105CY3	ABC transporter, permease
GA646_RS02495	ENOG4107PE3	Mammalian cell entry related domain protein
GA646_RS02500	ENOG4105E3I	toluene tolerance
GA646_RS02510	ENOG4107QUT	magnesium and cobalt transport protein CorA
GA646_RS02515	ENOG4108URH	decarboxylase
GA646_RS02525	ENOG4105MJ2	Competence protein
GA646_RS02530	ENOG4105CB5	ATP-dependent DNA helicase recG
GA646_RS02540	ENOG4105E55	glycerol-3-phosphate acyltransferase
GA646_RS02545	ENOG4105C29	acyl-CoA thioesterase
GA646_RS02550	ENOG4105CK2	sodium dicarboxylate symporter
GA646_RS02570	ENOG4105D7V	transposase
GA646_RS02585	ENOG4105KPV	Transcriptional regulator
GA646_RS02590	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GA646_RS02595	ENOG4105D7A	ATP-binding protein
GA646_RS02605	ENOG41089BK	Glutamine amido-transferase
GA646_RS02620	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GA646_RS02650	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GA646_RS02675	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GA646_RS02685	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GA646_RS02690	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GA646_RS02700	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GA646_RS02715	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GA646_RS02720	ENOG41067V7	50S ribosomal protein L36
GA646_RS02730	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GA646_RS02735	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GA646_RS02740	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GA646_RS02750	ENOG4105CT3	Monooxygenase
GA646_RS02755	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS02785	ENOG4105EMK	carboxylate amino acid amine transporter
GA646_RS02795	ENOG4105VKU	nucleicacid-binding protein
GA646_RS02800	ENOG4105DGW	oligopeptidase A
GA646_RS02805	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GA646_RS02840	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GA646_RS02870	ENOG4105QNF	Outer membrane lipoprotein
GA646_RS02930	ENOG4105DWV	Homoserine O-trans-acetylase
GA646_RS02935	ENOG4105DWV	Homoserine O-trans-acetylase
GA646_RS02940	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GA646_RS02950	ENOG4107E2E	PKHD-type hydroxylase
GA646_RS02955	ENOG4108IU3	tonb-dependent siderophore receptor
GA646_RS02960	ENOG4105D05	Receptor
GA646_RS02970	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GA646_RS02985	ENOG4107GFK	fumarate
GA646_RS02995	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GA646_RS03000	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GA646_RS03030	ENOG4105CN1	protease
GA646_RS03035	ENOG4105BZU	Histidine kinase
GA646_RS03045	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GA646_RS03060	ENOG4105F8V	Hydrolase, tatD family
GA646_RS03065	ENOG4105CUZ	uba thif-type nad fad binding protein
GA646_RS03070	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GA646_RS03105	ENOG4106UX7	integral membrane protein
GA646_RS03110	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GA646_RS03115	ENOG4105W8H	transhydrogenase (subunit alpha
GA646_RS03120	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GA646_RS03130	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GA646_RS03140	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
GA646_RS03145	ENOG4105BZU	Histidine kinase
GA646_RS03150	ENOG4105C6T	cysteine synthase
GA646_RS03165	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GA646_RS03175	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GA646_RS03180	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GA646_RS03185	ENOG4105VIE	preprotein translocase, subunit YajC
GA646_RS03200	ENOG4108V0P	LemA family
GA646_RS03210	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GA646_RS03220	ENOG4105E9K	Isocitrate dehydrogenase
GA646_RS03225	ENOG4105BZU	Histidine kinase
GA646_RS03230	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GA646_RS03235	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GA646_RS03240	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GA646_RS03260	ENOG410650X	lipopolysaccharide core region biosynthetic process
GA646_RS03265	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GA646_RS03270	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GA646_RS03280	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GA646_RS03285	ENOG4108SHN	Glycosyl transferase, family 2
GA646_RS03295	ENOG4105J5G	Transferase hexapeptide repeat containing protein
GA646_RS03315	ENOG4105C9M	aspartyl-trna synthetase
GA646_RS03325	ENOG4105UGU	tonB-dependent Receptor
GA646_RS03340	ENOG4105D7V	transposase
GA646_RS03350	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
GA646_RS03355	ENOG4105CSU	acyl-Coa dehydrogenase
GA646_RS03360	ENOG4105CSU	acyl-Coa dehydrogenase
GA646_RS03370	ENOG4105EB3	Histidine kinase
GA646_RS03375	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GA646_RS03385	ENOG4105MSB	protein, conserved in bacteria
GA646_RS03395	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS03415	ENOG4108WBT	adenosyltransferase
GA646_RS03420	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GA646_RS03430	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GA646_RS03465	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GA646_RS03470	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GA646_RS03485	ENOG4105D3R	alkyl hydroperoxide reductase
GA646_RS03500	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
GA646_RS03505	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GA646_RS03535	ENOG4108KHX	Diguanylate cyclase
GA646_RS03595	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GA646_RS03600	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GA646_RS03610	ENOG4105CRQ	synthase (Component I)
GA646_RS03625	ENOG4108RS6	transposase
GA646_RS03640	ENOG4105P8F	nudix hydrolase
GA646_RS03645	ENOG4108Z0R	Transferase
GA646_RS03650	ENOG41072GX	Peptidase M22 Glycoprotease
GA646_RS03655	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GA646_RS03675	ENOG4108M3P	Membrane
GA646_RS03685	ENOG4108RS6	transposase
GA646_RS03700	ENOG4105DJV	ribulose-phosphate 3-epimerase
GA646_RS03710	ENOG4105E3B	Multicopper oxidase
GA646_RS03720	ENOG4105KPY	Small multidrug resistance protein
GA646_RS03725	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GA646_RS03740	ENOG4105DWF	phosphomethylpyrimidine kinase
GA646_RS03745	ENOG4107XGZ	Hydrolase
GA646_RS03750	ENOG4105EW9	transcriptional regulator AsnC family
GA646_RS03765	ENOG4105M4H	endoribonuclease L-psp
GA646_RS03775	ENOG4108YXA	Membrane
GA646_RS03790	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GA646_RS03815	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GA646_RS03825	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GA646_RS03830	ENOG4105C3M	thioredoxin reductase
GA646_RS03835	ENOG4105CNU	cell division protein FtsK
GA646_RS03850	ENOG4107QMS	site-determining protein
GA646_RS03855	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GA646_RS03865	ENOG4106HNH	Acyl-transferase
GA646_RS03870	ENOG4108ZG0	Ompa motb domain protein
GA646_RS03875	ENOG4105C4R	Atp-dependent dna helicase
GA646_RS03880	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GA646_RS03885	ENOG4107QKV	phosphomannomutase
GA646_RS03920	ENOG4105E7A	Glutamine amidotransferase
GA646_RS03935	ENOG4105VDB	UPF0125 protein
GA646_RS03945	ENOG41090R7	Ferric uptake
GA646_RS03950	ENOG4105CZX	twitching motility protein
GA646_RS03955	ENOG4105CZX	twitching motility protein
GA646_RS03960	ENOG4105DFA	alanine racemase domain protein
GA646_RS03970	ENOG4105EYH	Exonuclease
GA646_RS03975	ENOG4107RH8	nuclease SbcCD subunit D
GA646_RS03985	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GA646_RS03990	ENOG4105D52	delta-aminolevulinic acid dehydratase
GA646_RS03995	ENOG4108VUY	thioesterase Superfamily protein
GA646_RS04000	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GA646_RS04010	ENOG4105DFP	Integrase
GA646_RS04045	ENOG4105MZU	cell filamentation protein
GA646_RS04055	ENOG4105CVR	type I restriction-modification system
GA646_RS04065	ENOG4105DFS	Conserved Protein
GA646_RS04100	ENOG4105EPF	Outer membrane porin
GA646_RS04105	ENOG4105D2S	major facilitator superfamily
GA646_RS04110	ENOG4107HP6	Transcriptional regulator
GA646_RS04115	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
GA646_RS04120	ENOG4107HP6	Transcriptional regulator
GA646_RS04125	ENOG4107QP7	CoA-transferase subunit A
GA646_RS04130	ENOG4107QNJ	CoA-transferase subunit B
GA646_RS04135	ENOG4105CHU	acetyl-coa acetyltransferase
GA646_RS04140	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
GA646_RS04145	ENOG4105F2Z	3-oxoadipate enol-lactonase
GA646_RS04150	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
GA646_RS04155	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
GA646_RS04160	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
GA646_RS04185	ENOG4105EPF	Outer membrane porin
GA646_RS04190	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS04205	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
GA646_RS04210	ENOG4108SC4	)-transporter
GA646_RS04225	ENOG4105E3J	oxidoreductase
GA646_RS04240	ENOG4107R3N	Filamentation induced by cAMP protein fic
GA646_RS04260	ENOG4107BJW	polysaccharide deacetylase
GA646_RS04265	ENOG4105CND	Glycosyl transferase, family 2
GA646_RS04310	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GA646_RS04315	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GA646_RS04320	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GA646_RS04325	ENOG4105DFF	Rod shape-determining protein mreb
GA646_RS04330	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GA646_RS04335	ENOG4105VQ7	Rod shape-determining protein MreD
GA646_RS04340	ENOG4108Z03	MAF-like protein
GA646_RS04345	ENOG4105C03	ribonuclease
GA646_RS04355	ENOG4105D8T	Acyltransferase
GA646_RS04365	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
GA646_RS04395	ENOG4108RXX	maleylacetoacetate isomerase
GA646_RS04420	ENOG4105C85	amino acid
GA646_RS04425	ENOG4105C7F	AcnD-accessory protein PrpF
GA646_RS04430	ENOG4105CTB	Polyprenyl synthetase
GA646_RS04440	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GA646_RS04455	ENOG4105GKE	subunit e
GA646_RS04460	ENOG4107QIZ	NADH dehydrogenase
GA646_RS04465	ENOG4108IEH	NADH dehydrogenase subunit g
GA646_RS04470	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GA646_RS04475	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GA646_RS04480	ENOG4107UFS	subunit j
GA646_RS04485	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GA646_RS04490	ENOG4105D65	subunit l
GA646_RS04495	ENOG4105C8S	subunit m
GA646_RS04510	ENOG4105VEQ	Cold shock protein
GA646_RS04520	ENOG4105DUM	transcriptional regulator, lysR family
GA646_RS04525	ENOG4105DP0	ferredoxin-NADP reductase
GA646_RS04555	ENOG4105CBX	hi0933 family
GA646_RS04570	ENOG4105K6H	D-cysteine desulfhydrase
GA646_RS04590	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GA646_RS04595	ENOG4105D1F	ATP-binding protein
GA646_RS04645	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GA646_RS04675	ENOG4105M3Z	response regulator
GA646_RS04690	ENOG4105CBS	Chea signal transduction histidine kinase
GA646_RS04705	ENOG4106BSU	Entericidin B
GA646_RS04715	ENOG4105WD1	Membrane
GA646_RS04720	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
GA646_RS04775	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GA646_RS04785	ENOG4105EM2	membrane
GA646_RS04790	ENOG4105C2C	drug resistance transporter, Bcr CflA
GA646_RS04805	ENOG4105D6U	Sodium Glutamate Symporter
GA646_RS04810	ENOG4105BZG	amino acid carrier protein
GA646_RS04815	ENOG4105FGV	Chromate
GA646_RS04820	ENOG4105D78	K07001 NTE family protein
GA646_RS04835	ENOG4105YIP	Tetr family transcriptional regulator
GA646_RS04840	ENOG4105CZM	Major Facilitator
GA646_RS04845	ENOG4108W5M	transcriptional regulator
GA646_RS04850	ENOG4108K3A	Glutathione S-transferase
GA646_RS04865	ENOG4105CKI	cobalamin synthesis protein
GA646_RS04870	ENOG4108VWS	Yaeq family
GA646_RS04885	ENOG4108RS6	transposase
GA646_RS04935	ENOG4105CSV	Glutaminase
GA646_RS04940	ENOG4105CMT	Dihydroxyacetone kinase
GA646_RS04950	ENOG4105IYK	transposase
GA646_RS04960	ENOG4105E5H	Transposase
GA646_RS04970	ENOG4105C3R	Methionine synthase
GA646_RS04975	ENOG4105CJ3	phosphate transporter
GA646_RS05000	ENOG4105D05	Receptor
GA646_RS05025	ENOG4108UJV	acyl-CoA thioesterase i
GA646_RS05030	ENOG4108I0Y	(ABC) transporter
GA646_RS05035	ENOG4105CV6	ABC transporter, permease
GA646_RS05040	ENOG4107U91	Rhomboid family
GA646_RS05045	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GA646_RS05055	ENOG4105C5Q	Transcriptional regulator
GA646_RS05065	ENOG4107QZF	nitrite reductase NADPH large subunit
GA646_RS05070	ENOG4105VCQ	rubredoxin
GA646_RS05075	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GA646_RS05095	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GA646_RS05100	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GA646_RS05105	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS05135	ENOG4105C37	(CBS) domain
GA646_RS05145	ENOG4107RET	Isocitrate lyase
GA646_RS05155	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
GA646_RS05160	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GA646_RS05170	ENOG4105CHR	reductase
GA646_RS05190	ENOG4105CQM	Urea amidohydrolase subunit alpha
GA646_RS05205	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GA646_RS05220	ENOG4106H78	methyltransferase
GA646_RS05225	ENOG4105CJN	penicillin-binding protein
GA646_RS05250	ENOG4105CSM	endonuclease III
GA646_RS05255	ENOG4108R3D	Electron transport complex
GA646_RS05260	ENOG4105D82	Glutamate dehydrogenase
GA646_RS05270	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GA646_RS05280	ENOG4107VAM	peptidase, m28
GA646_RS05290	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GA646_RS05320	ENOG4105DAA	L-lactate
GA646_RS05325	ENOG41073TP	transcriptional regulator
GA646_RS05335	ENOG4105CXG	d-lactate dehydrogenase
GA646_RS05365	ENOG4105E07	UPF0149 protein
GA646_RS05370	ENOG4107RAQ	aminopeptidase
GA646_RS05375	ENOG4105D0A	hydroxylase
GA646_RS05380	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GA646_RS05390	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GA646_RS05395	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GA646_RS05405	ENOG4105W4M	Transport-associated protein
GA646_RS05410	ENOG4105EBR	Carboxylesterase
GA646_RS05415	ENOG4105E09	nadh pyrophosphatase
GA646_RS05425	ENOG4107RZZ	dna polymerase iii epsilon subunit
GA646_RS05430	ENOG4105E9H	Lytic Murein transglycosylase
GA646_RS05435	ENOG4105E43	Extracellular solute-binding protein, family 5
GA646_RS05440	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GA646_RS05445	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GA646_RS05450	ENOG4108JQ5	ABC transporter
GA646_RS05480	ENOG4108IQI	permease
GA646_RS05500	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GA646_RS05505	ENOG4105EKE	dihydroorotase
GA646_RS05525	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GA646_RS05600	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GA646_RS05610	ENOG4105C6K	Malic enzyme
GA646_RS05615	ENOG4105BZU	Histidine kinase
GA646_RS05620	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GA646_RS05625	ENOG4105SYT	Methylenetetrahydrofolate reductase
GA646_RS05630	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GA646_RS05655	ENOG4107QPN	acyl-Coa dehydrogenase
GA646_RS05660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GA646_RS05670	ENOG4105E2B	Taurine dioxygenase
GA646_RS05685	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GA646_RS05690	ENOG4105CE9	30S ribosomal protein S2
GA646_RS05715	ENOG4105CVE	Lytic murein transglycosylase
GA646_RS05730	ENOG4105E3A	(ABC) transporter
GA646_RS05735	ENOG4105DA5	(ABC) transporter
GA646_RS05790	ENOG4105NXH	GreA GreB family elongation factor
GA646_RS05810	ENOG4108JU3	Alkyl hydroperoxide reductase
GA646_RS05815	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GA646_RS05820	ENOG4105CFP	Peptidase U32
GA646_RS05830	ENOG41082YX	Transcriptional regulator, arsr family
GA646_RS05840	ENOG4105D6J	arsenicaL-resistance protein
GA646_RS05845	ENOG4105CAU	Arsenical resistance protein, ArsH
GA646_RS05860	ENOG4105DP0	ferredoxin-NADP reductase
GA646_RS05865	ENOG4108R96	Methyltransferase, YaeB family
GA646_RS05875	ENOG4107QHF	type ii secretion system protein e
GA646_RS05885	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GA646_RS05890	ENOG4105DHQ	Histidine kinase
GA646_RS05910	ENOG4105BZ4	penicillin-binding protein
GA646_RS05915	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GA646_RS05920	ENOG4105VUT	cytoplasmic protein
GA646_RS05935	ENOG4105CK2	sodium dicarboxylate symporter
GA646_RS05940	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS05945	ENOG4107R7Y	intracellular protease Pfpi family
GA646_RS05950	ENOG4105CQC	Prephenate dehydratase
GA646_RS05955	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GA646_RS05960	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GA646_RS05985	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GA646_RS05990	ENOG4105CEP	NADH dehydrogenase
GA646_RS05995	ENOG4105DZ1	carboxypeptidase
GA646_RS06010	ENOG4108R99	pseudouridine synthase
GA646_RS06020	ENOG4105FAA	peptidase M23
GA646_RS06030	ENOG4108MEJ	flavin reductase domain protein
GA646_RS06035	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GA646_RS06075	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GA646_RS06105	ENOG4105D3G	Pseudouridine synthase
GA646_RS06110	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GA646_RS06120	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
GA646_RS06125	ENOG4105EJ2	Transcriptional regulator
GA646_RS06145	ENOG4107QS8	(LipO)protein
GA646_RS06165	ENOG4105VEQ	Cold shock protein
GA646_RS06170	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GA646_RS06180	ENOG4105EA8	2-Nitropropane dioxygenase
GA646_RS06205	ENOG41066VF	YeeE YedE family protein
GA646_RS06215	ENOG4108JU3	Alkyl hydroperoxide reductase
GA646_RS06240	ENOG4105D3R	alkyl hydroperoxide reductase
GA646_RS06245	ENOG4105CQ7	ATP-dependent helicase
GA646_RS06270	ENOG4105C2X	Arabinose 5-phosphate isomerase
GA646_RS06275	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GA646_RS06285	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GA646_RS06290	ENOG4108IUZ	ABC transporter
GA646_RS06295	ENOG4105DFG	type I secretion outer membrane protein
GA646_RS06300	ENOG4108JJA	ABC, transporter
GA646_RS06305	ENOG4107QZV	Type I secretion membrane fusion protein
GA646_RS06325	ENOG4107ZBN	O-methyltransferase
GA646_RS06335	ENOG4108Z4U	Ferredoxin
GA646_RS06360	ENOG4108RS6	transposase
GA646_RS06390	ENOG4105C0B	DNA polymerase III (alpha subunit)
GA646_RS06395	ENOG4108UMI	ABC transporter, permease
GA646_RS06400	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GA646_RS06405	ENOG4105D01	(LipO)protein
GA646_RS06415	ENOG4105C12	Phosphoribosylglycinamide synthetase
GA646_RS06420	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GA646_RS06425	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GA646_RS06490	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GA646_RS06495	ENOG4105CDU	Replicative dna helicase
GA646_RS06505	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GA646_RS06520	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GA646_RS06525	ENOG4105CCU	oxidase (Subunit III)
GA646_RS06530	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GA646_RS06535	ENOG4105E2S	oxidase) subunit II
GA646_RS06560	ENOG4105DEN	Luciferase family
GA646_RS06575	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GA646_RS06580	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GA646_RS06585	ENOG4105FFC	UPF0187 protein
GA646_RS06605	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS06625	ENOG4105D06	uba thif-type nad fad binding protein
GA646_RS06635	ENOG4105KRF	dihydroneopterin aldolase
GA646_RS06655	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GA646_RS06680	ENOG4107QIJ	Aconitate hydratase 2
GA646_RS06700	ENOG4105D6U	Sodium Glutamate Symporter
GA646_RS06730	ENOG4105CD8	aminopeptidase N
GA646_RS06745	ENOG41081QV	Universal stress protein
GA646_RS06755	ENOG4105DKK	Benzoate
GA646_RS06760	ENOG4108NIW	Leucine export protein LeuE
GA646_RS06765	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GA646_RS06770	ENOG4105EVZ	LysR family transcriptional regulator
GA646_RS06780	ENOG4105CHU	acetyl-coa acetyltransferase
GA646_RS06785	ENOG4105CHR	reductase
GA646_RS06805	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GA646_RS06815	ENOG4105C0A	alcohol dehydrogenase
GA646_RS06820	ENOG4105KJF	protein tyrosine phosphatase
GA646_RS06840	ENOG4105CBC	glutamate synthase
GA646_RS06850	ENOG4105BZU	Histidine kinase
GA646_RS06855	ENOG4105EZE	Cupin 4 family protein
GA646_RS06860	ENOG4108UHJ	MAF-like protein
GA646_RS06880	ENOG4105D2N	Aldolase
GA646_RS06885	ENOG4108TZV	Membrane
GA646_RS06895	ENOG4108RCM	Nitroreductase
GA646_RS06900	ENOG4105CNV	Aldolase
GA646_RS06925	ENOG4108T58	Mg2 transport protein CorA
GA646_RS06945	ENOG4105C26	Dehydrogenase
GA646_RS06950	ENOG4105EW9	transcriptional regulator AsnC family
GA646_RS06955	ENOG4105CK7	Sodium proline symporter
GA646_RS06960	ENOG4108IJ0	Aspartate ammonia-lyase
GA646_RS06965	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GA646_RS06970	ENOG4105W8I	Transcriptional regulator
GA646_RS06975	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS06995	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GA646_RS07010	ENOG4105F27	Major Facilitator
GA646_RS07015	ENOG4105CV8	reductase
GA646_RS07020	ENOG4105HEI	LysR family (Transcriptional regulator
GA646_RS07040	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GA646_RS07045	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GA646_RS07055	ENOG4105CNI	cell division protein FtsW
GA646_RS07070	ENOG4105Y3E	Modulates RecA activity (By similarity)
GA646_RS07080	ENOG4105VEJ	Heat shock protein
GA646_RS07085	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
GA646_RS07090	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GA646_RS07110	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS07120	ENOG4105K4T	epimerase
GA646_RS07125	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GA646_RS07140	ENOG4108JA2	transcriptioN-repair coupling factor
GA646_RS07150	ENOG4105F8J	Adenylate Guanylate cyclase
GA646_RS07155	ENOG4108ZIT	Ferredoxin, 2FE-2S
GA646_RS07170	ENOG4108Z4V	iron-sulfur cluster assembly
GA646_RS07175	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GA646_RS07185	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GA646_RS07200	ENOG4105K70	DNA-binding protein
GA646_RS07205	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GA646_RS07230	ENOG4105K59	histidine triad (HIT) protein
GA646_RS07250	ENOG4105C28	cystathionine
GA646_RS07260	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GA646_RS07290	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GA646_RS07295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GA646_RS07330	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GA646_RS07375	ENOG4107RKG	DJ-1/PfpI family
GA646_RS07390	ENOG4108Z66	YbaK ebsC protein
GA646_RS07395	ENOG41067MG	lrgb family
GA646_RS07400	ENOG4105VAW	lrga family
GA646_RS07405	ENOG4105CMU	LysR family (Transcriptional regulator
GA646_RS07425	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GA646_RS07430	ENOG4105CMR	udp-glucose 4-epimerase
GA646_RS07445	ENOG4105X58	receptor
GA646_RS07460	ENOG4105CSU	acyl-Coa dehydrogenase
GA646_RS07465	ENOG4105CF7	AraC family transcriptional regulator
GA646_RS07470	ENOG4105CZM	Major Facilitator
GA646_RS07480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GA646_RS07485	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GA646_RS07495	ENOG4105KK6	nuclease
GA646_RS07505	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS07545	ENOG4107RZC	phospholipase d
GA646_RS07555	ENOG4105BZU	Histidine kinase
GA646_RS07565	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GA646_RS07570	ENOG4105CZX	twitching motility protein
GA646_RS07575	ENOG4105CZM	Major Facilitator
GA646_RS07585	ENOG4108ZX5	transcriptional regulator
GA646_RS07595	ENOG4105BZ1	(ABC) transporter
GA646_RS07610	ENOG4105CUY	Mechanosensitive ion channel
GA646_RS07615	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
GA646_RS07635	ENOG41080HT	Transcriptional regulator, arsr family
GA646_RS07640	ENOG4105E55	glycerol-3-phosphate acyltransferase
GA646_RS07645	ENOG4105C6T	cysteine synthase
GA646_RS07660	ENOG4107RNU	major facilitator superfamily MFS_1
GA646_RS07665	ENOG4107QZF	nitrite reductase NADPH large subunit
GA646_RS07670	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GA646_RS07700	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GA646_RS07705	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GA646_RS07715	ENOG4105E0C	molybdate abc transporter
GA646_RS07720	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GA646_RS07725	ENOG4105DDW	LysR family Transcriptional regulator
GA646_RS07745	ENOG4105F2Z	3-oxoadipate enol-lactonase
GA646_RS07750	ENOG4105CHU	acetyl-coa acetyltransferase
GA646_RS07755	ENOG4107QNJ	CoA-transferase subunit B
GA646_RS07760	ENOG4107QP7	CoA-transferase subunit A
GA646_RS07765	ENOG4105DKK	Benzoate
GA646_RS07770	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
GA646_RS07775	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
GA646_RS07780	ENOG4108UKV	benzoate 1,2-dioxygenase
GA646_RS07785	ENOG4105FUY	alpha subunit
GA646_RS07795	ENOG4105NN7	muconolactone delta-isomerase
GA646_RS07800	ENOG4105DTQ	mandelate racemase muconate lactonizing
GA646_RS07805	ENOG4108KB2	LysR family Transcriptional regulator
GA646_RS07810	ENOG4105D2S	major facilitator superfamily
GA646_RS07850	ENOG4106UW1	Major Facilitator superfamily
GA646_RS07860	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
GA646_RS07865	ENOG4105TMB	Formate nitrite transporter
GA646_RS07875	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GA646_RS07885	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS07890	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS07895	ENOG4107RGD	Major Facilitator superfamily
GA646_RS07900	ENOG4107QP7	CoA-transferase subunit A
GA646_RS07905	ENOG4107QNJ	CoA-transferase subunit B
GA646_RS07920	ENOG4107RGD	Major Facilitator superfamily
GA646_RS07930	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GA646_RS07935	ENOG4105CHU	acetyl-coa acetyltransferase
GA646_RS07945	ENOG4105MP9	class II Aldolase
GA646_RS07950	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GA646_RS07955	ENOG4108UKI	Enoyl-CoA hydratase
GA646_RS07960	ENOG4105EA8	2-Nitropropane dioxygenase
GA646_RS07965	ENOG4105CSU	acyl-Coa dehydrogenase
GA646_RS07970	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GA646_RS07975	ENOG4107RN6	Monooxygenase
GA646_RS07980	ENOG4107RGD	Major Facilitator superfamily
GA646_RS07985	ENOG4105CEY	Amp-dependent synthetase and ligase
GA646_RS07995	ENOG4107RGD	Major Facilitator superfamily
GA646_RS08000	ENOG4108U05	Transcriptional regulator
GA646_RS08010	ENOG4108IPT	Naphthoate synthase
GA646_RS08020	ENOG4105CEY	Amp-dependent synthetase and ligase
GA646_RS08035	ENOG4105C26	Dehydrogenase
GA646_RS08040	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GA646_RS08050	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS08055	ENOG4105E39	Enoyl-CoA hydratase
GA646_RS08070	ENOG4105C94	Transporter
GA646_RS08075	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GA646_RS08095	ENOG4105DHQ	Histidine kinase
GA646_RS08105	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GA646_RS08110	ENOG4107QX9	Thiol disulfide interChange protein
GA646_RS08115	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
GA646_RS08125	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
GA646_RS08140	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
GA646_RS08145	ENOG4105HF0	Membrane
GA646_RS08165	ENOG4107Z3H	Transcriptional regulator, TetR family
GA646_RS08195	ENOG4105EV9	Alpha Beta Hydrolase
GA646_RS08255	ENOG4105IYK	transposase
GA646_RS08265	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GA646_RS08270	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GA646_RS08285	ENOG4105D8G	Major Facilitator superfamily
GA646_RS08335	ENOG4105CEV	competence damage-inducible protein
GA646_RS08345	ENOG4105BZN	citrate synthase
GA646_RS08350	ENOG4105CR4	methylisocitrate lyase
GA646_RS08365	ENOG4105CSH	Transporter
GA646_RS08380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GA646_RS08385	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GA646_RS08405	ENOG4105E66	phosphoriboisomerase A
GA646_RS08410	ENOG4105C7B	Threonine dehydratase
GA646_RS08420	ENOG4105CZN	Potassium uptake protein
GA646_RS08425	ENOG4105HDD	phospholipase
GA646_RS08450	ENOG4105PV3	Inner membrane protein yqiJ
GA646_RS08460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GA646_RS08465	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GA646_RS08485	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GA646_RS08505	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS08510	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS08515	ENOG4108MJ3	acetyltransferase
GA646_RS08520	ENOG4105EEF	Alkane 1-monooxygenase
GA646_RS08525	ENOG4105E7U	AraC family transcriptional regulator
GA646_RS08530	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GA646_RS08535	ENOG4107TSN	permease
GA646_RS08540	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GA646_RS08570	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GA646_RS08590	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA646_RS08595	ENOG4105DZP	Membrane-associated zinc metalloprotease
GA646_RS08605	ENOG4105KNE	Phosphatidate cytidylyltransferase
GA646_RS08610	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GA646_RS08615	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GA646_RS08630	ENOG4105CUX	Signal transduction histidine kinase
GA646_RS08635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GA646_RS08645	ENOG4105CC0	LysR family Transcriptional regulator
GA646_RS08650	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GA646_RS08655	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GA646_RS08675	ENOG4105EE5	Membrane protein terC
GA646_RS08695	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS08700	ENOG4107QP3	malate synthase g
GA646_RS08705	ENOG4105D6Z	AFG1 family ATPase
GA646_RS08715	ENOG4107RN6	Monooxygenase
GA646_RS08720	ENOG4105DWU	Membrane
GA646_RS08725	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GA646_RS08735	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GA646_RS08740	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GA646_RS08755	ENOG4108Z6B	deaminase
GA646_RS08765	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GA646_RS08775	ENOG4108RTD	type II secretion system protein K
GA646_RS08800	ENOG4105F8V	Hydrolase, tatD family
GA646_RS08810	ENOG4107QRG	dna polymerase iii
GA646_RS08820	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GA646_RS08825	ENOG4105BZ1	(ABC) transporter
GA646_RS08840	ENOG4105FA0	parb-like partition protein
GA646_RS08845	ENOG4107QJE	Chromosome Partitioning Protein
GA646_RS08855	ENOG4108S0S	Nucleotidyl transferase
GA646_RS08860	ENOG4105EHM	Aminoglycoside phosphotransferase
GA646_RS08865	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GA646_RS08870	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GA646_RS08875	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GA646_RS08885	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GA646_RS08890	ENOG4105K8N	protein family UPF0079, ATPase
GA646_RS08910	ENOG4105I08	Pseudouridine synthase
GA646_RS08915	ENOG4108VMM	UPF0756 membrane protein
GA646_RS08925	ENOG4105DZ2	Transcriptional regulator
GA646_RS08930	ENOG4107QUV	Domain protein
GA646_RS08950	ENOG4107RR1	TRANSCRIPTIONal
GA646_RS08960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GA646_RS08965	ENOG4108YYC	ycei family
GA646_RS08975	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GA646_RS08980	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GA646_RS08985	ENOG4105N0V	mono-oxygenase ydhR
GA646_RS09000	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GA646_RS09015	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GA646_RS09020	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GA646_RS09025	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GA646_RS09045	ENOG4105CEY	Amp-dependent synthetase and ligase
GA646_RS09050	ENOG4108Z0R	Transferase
GA646_RS09055	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
GA646_RS09060	ENOG4105DZS	Phenylacetate-CoA ligase
GA646_RS09070	ENOG4105DNH	Major Facilitator
GA646_RS09090	ENOG4105BZU	Histidine kinase
GA646_RS09100	ENOG4107T32	3-phytase (EC 3.1.3.8)
GA646_RS09105	ENOG4105E02	MotA TolQ exbB proton channel
GA646_RS09110	ENOG4105M8F	Biopolymer transport protein exbD tolR
GA646_RS09120	ENOG4105CNM	Receptor
GA646_RS09155	ENOG4105DWT	malate dehydrogenase (quinone)
GA646_RS09225	ENOG4107QKA	exodeoxyribonuclease V beta
GA646_RS09260	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GA646_RS09290	ENOG4105CHR	reductase
GA646_RS09300	ENOG4105C7S	Dehydrogenase
GA646_RS09305	ENOG4105CPP	Dehydrogenase, E1 component
GA646_RS09310	ENOG4107R0V	Pyruvate dehydrogenase
GA646_RS09315	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GA646_RS09330	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GA646_RS09355	ENOG4105C3G	gtp-binding protein
GA646_RS09365	ENOG4108UMN	azlc family
GA646_RS09370	ENOG4105ZED	uncharacterized protein ygaH
GA646_RS09375	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GA646_RS09380	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GA646_RS09390	ENOG4108V06	Glutathione peroxidase
GA646_RS09395	ENOG4105E0X	reductase
GA646_RS09400	ENOG4105CHM	Aminotransferase
GA646_RS09405	ENOG4105EXC	Acyl-transferase
GA646_RS09445	ENOG4105D9P	serine threonine protein kinase
GA646_RS09470	ENOG4105VCC	30S ribosomal protein S21
GA646_RS09475	ENOG4105KTH	gatB Yqey
GA646_RS09490	ENOG4105ERG	peptidase m48, ste24p
GA646_RS09510	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GA646_RS09555	ENOG4105C1J	atp-dependent rna helicase
GA646_RS09560	ENOG4105VEQ	Cold shock protein
GA646_RS09570	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GA646_RS09575	ENOG4105M08	Membrane
GA646_RS09590	ENOG4108K3A	Glutathione S-transferase
GA646_RS09595	ENOG4105CHH	sulfate transporter
GA646_RS09605	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GA646_RS09625	ENOG4105CEY	Amp-dependent synthetase and ligase
GA646_RS09630	ENOG4108SGK	Tetr family transcriptional regulator
GA646_RS09635	ENOG4105C1G	acyl-Coa dehydrogenase
GA646_RS09640	ENOG4107QX3	carboxylase
GA646_RS09645	ENOG4105E39	Enoyl-CoA hydratase
GA646_RS09655	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GA646_RS09665	ENOG4107QNJ	CoA-transferase subunit B
GA646_RS09670	ENOG4105CDV	Ompa motb domain protein
GA646_RS09675	ENOG4105CD3	dihydroorotase
GA646_RS09680	ENOG4105CXT	aspartate transcarbamylase
GA646_RS09695	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GA646_RS09700	ENOG4108UKZ	OsmC family
GA646_RS09705	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GA646_RS09710	ENOG4105CPC	Aldo Keto reductase
GA646_RS09725	ENOG4108K0D	peptidase, M48
GA646_RS09730	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GA646_RS09745	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GA646_RS09755	ENOG4105CFH	Aspartokinase
GA646_RS09765	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GA646_RS09775	ENOG4105C3Q	Glycosyl transferase, family 2
GA646_RS09785	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GA646_RS09790	ENOG4105C7N	Xanthine uracil vitamin C permease
GA646_RS09815	ENOG4105CAR	Terminase, large subunit
GA646_RS09880	ENOG4105F8C	transglutaminase domain-containing protein
GA646_RS09890	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GA646_RS09895	ENOG4105VCD	cytoplasmic protein
GA646_RS09900	ENOG4105D22	carbon starvation protein
GA646_RS09905	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GA646_RS09910	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GA646_RS09930	ENOG4105DHU	Bile acid
GA646_RS09945	ENOG4105DAN	ATP-dependent protease
GA646_RS09950	ENOG4105M2J	Glutaredoxin
GA646_RS09955	ENOG4105C8Y	Acetylornithine aminotransferase
GA646_RS09960	ENOG4105EJC	lysr family transcriptional regulator
GA646_RS09965	ENOG4108K5P	(LipO)protein
GA646_RS09970	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GA646_RS09985	ENOG4105DZ1	carboxypeptidase
GA646_RS09990	ENOG4108Z0R	Transferase
GA646_RS09995	ENOG4105BZW	Glycerate kinase
GA646_RS10025	ENOG4107QTF	adenylosuccinate lyase
GA646_RS10035	ENOG4105ERU	peptidase
GA646_RS10040	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GA646_RS10050	ENOG4105C8U	phosphate abc transporter
GA646_RS10060	ENOG4105DY8	decarboxylase
GA646_RS10065	ENOG4108JPW	Aminotransferase
GA646_RS10075	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GA646_RS10085	ENOG4105EQ0	Major Facilitator superfamily
GA646_RS10090	ENOG4105KVH	Transcriptional regulator
GA646_RS10095	ENOG4105ECR	NmrA family
GA646_RS10115	ENOG4105DTR	rard protein
GA646_RS10125	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GA646_RS10145	ENOG4105CHM	Aminotransferase
GA646_RS10165	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GA646_RS10170	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GA646_RS10175	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GA646_RS10185	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GA646_RS10190	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GA646_RS10200	ENOG4105C3F	Signal peptidase i
GA646_RS10215	ENOG4105C0H	protease
GA646_RS10220	ENOG4108IYU	L-aspartate oxidase
GA646_RS10225	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
GA646_RS10240	ENOG4105HHA	aminodeoxychorismate lyase
GA646_RS10250	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GA646_RS10260	ENOG4108I5D	sulfate abc transporter
GA646_RS10270	ENOG4108IJ6	ABC transporter
GA646_RS10275	ENOG4107R11	Transcriptional regulator
GA646_RS10295	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GA646_RS10300	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GA646_RS10310	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GA646_RS10315	ENOG4108YYC	ycei family
GA646_RS10325	ENOG4105CGU	Enoyl-CoA hydratase
GA646_RS10345	ENOG4108ETH	Formylglycinamide ribotide synthetase
GA646_RS10365	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GA646_RS10375	ENOG4107SCA	Formamidase (EC 3.5.1.49)
GA646_RS10380	ENOG4105CH2	amidohydrolase
GA646_RS10385	ENOG4107YD3	Thioesterase
GA646_RS10390	ENOG4105E02	MotA TolQ exbB proton channel
GA646_RS10395	ENOG4105M8F	Biopolymer transport protein exbD tolR
GA646_RS10405	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GA646_RS10410	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GA646_RS10415	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS10460	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GA646_RS10465	ENOG4105C02	permease
GA646_RS10470	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GA646_RS10475	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GA646_RS10495	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GA646_RS10500	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GA646_RS10505	ENOG4105D60	lipoprotein releasing system transmembrane protein
GA646_RS10520	ENOG4108UPT	UPF0178 protein
GA646_RS10540	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GA646_RS10550	ENOG4105C10	Electron transfer flavoprotein
GA646_RS10555	ENOG4105BZJ	Electron transfer flavoprotein
GA646_RS10560	ENOG4105N14	lysine exporter protein LysE YggA
GA646_RS10565	ENOG4108YXU	transcriptional regulator AsnC family
GA646_RS10575	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GA646_RS10590	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GA646_RS10600	ENOG4105C85	amino acid
GA646_RS10605	ENOG4105BZG	amino acid carrier protein
GA646_RS10610	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GA646_RS10620	ENOG4105C0H	protease
GA646_RS10625	ENOG4107QNR	UPF0135 protein
GA646_RS10630	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GA646_RS10665	ENOG4108W5M	transcriptional regulator
GA646_RS10675	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GA646_RS10685	ENOG4105C5F	glutamine synthetase
GA646_RS10690	ENOG4105DDQ	anthranilate synthase
GA646_RS10710	ENOG4105EUJ	GTP cyclohydrolase i
GA646_RS10720	ENOG4105BZU	Histidine kinase
GA646_RS10735	ENOG4105NX3	Membrane
GA646_RS10740	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GA646_RS10750	ENOG4105C2I	pirin domain protein
GA646_RS10770	ENOG4108RRZ	Transcription elongation factor GreB
GA646_RS10775	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GA646_RS10785	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GA646_RS10790	ENOG4105E4C	Lytic transglycosylase catalytic
GA646_RS10795	ENOG4105D0M	Protease HtpX homolog
GA646_RS10800	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS10810	ENOG4105CJW	magnesium transporter
GA646_RS10815	ENOG4105BZS	acriflavin resistance protein
GA646_RS10865	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GA646_RS10925	ENOG4105EEI	dihydropteroate synthase
GA646_RS10935	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GA646_RS10945	ENOG4105HBR	Rna-binding protein
GA646_RS10960	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GA646_RS10965	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GA646_RS10975	ENOG4108Q5F	Tetr family transcriptional regulator
GA646_RS10980	ENOG4108UQ8	endoribonuclease L-psp
GA646_RS10985	ENOG4105EQK	-acetyltransferase
GA646_RS10990	ENOG4108YV4	Universal stress protein
GA646_RS11000	ENOG4105CGZ	zinc metallopeptidase
GA646_RS11005	ENOG4105CKW	Inner membrane protein yedI
GA646_RS11025	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GA646_RS11035	ENOG4107QN2	dihydrolipoyl dehydrogenase
GA646_RS11040	ENOG4105C7S	Dehydrogenase
GA646_RS11045	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GA646_RS11050	ENOG4105E33	succinate dehydrogenase
GA646_RS11060	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GA646_RS11065	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GA646_RS11075	ENOG4105F95	Monooxygenase
GA646_RS11090	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GA646_RS11105	ENOG4105C4K	Nad synthetase
GA646_RS11135	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GA646_RS11145	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GA646_RS11155	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GA646_RS11160	ENOG4105C34	Pseudouridine synthase
GA646_RS11165	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GA646_RS11170	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GA646_RS11185	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GA646_RS11215	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GA646_RS11235	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS11260	ENOG4107T5V	SNARE associated Golgi
GA646_RS11290	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GA646_RS11300	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GA646_RS11315	ENOG4105CUB	amino acid
GA646_RS11320	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GA646_RS11325	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GA646_RS11330	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GA646_RS11340	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GA646_RS11365	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GA646_RS11370	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GA646_RS11375	ENOG4105BZS	acriflavin resistance protein
GA646_RS11380	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GA646_RS11385	ENOG4105K8R	UPF0145 protein
GA646_RS11390	ENOG4105K8R	UPF0145 protein
GA646_RS11395	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
GA646_RS11405	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GA646_RS11415	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GA646_RS11430	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
GA646_RS11445	ENOG4107VMU	Membrane
GA646_RS11455	ENOG4107RP9	extracellular solute-binding protein, family 3
GA646_RS11460	ENOG4105EAD	ABC transporter
GA646_RS11465	ENOG4105DRP	amino acid AbC transporter
GA646_RS11470	ENOG4105CDA	abc transporter atp-binding protein
GA646_RS11475	ENOG4108UHE	carbonic anhydrase
GA646_RS11490	ENOG4105D78	K07001 NTE family protein
GA646_RS11505	ENOG4105CK7	Sodium proline symporter
GA646_RS11510	ENOG4105JJR	Histidine kinase
GA646_RS11515	ENOG4107EXC	regulatoR
GA646_RS11520	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GA646_RS11530	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GA646_RS11535	ENOG4109066	lysm domain bon superfamily protein
GA646_RS11545	ENOG4105CHR	reductase
GA646_RS11550	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GA646_RS11555	ENOG4105VGS	50s ribosomal protein l32
GA646_RS11560	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GA646_RS11565	ENOG4108BPE	-transporting atpase
GA646_RS11570	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GA646_RS11585	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GA646_RS11590	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GA646_RS11595	ENOG4105FE9	pseudouridine synthase
GA646_RS11605	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GA646_RS11610	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GA646_RS11620	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GA646_RS11625	ENOG4108UWD	Iron-storage protein
GA646_RS11630	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GA646_RS11635	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GA646_RS11640	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GA646_RS11650	ENOG4105HF0	Membrane
GA646_RS11670	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GA646_RS11680	ENOG4105FDP	GntR family transcriptional regulator
GA646_RS11710	ENOG4105DSF	transport protein
GA646_RS11720	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GA646_RS11725	ENOG4105K78	MarR family Transcriptional regulator
GA646_RS11740	ENOG4105D3G	Pseudouridine synthase
GA646_RS11745	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
GA646_RS11770	ENOG4108I0Z	Aconitate hydratase
GA646_RS11775	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GA646_RS11790	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GA646_RS11805	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GA646_RS11840	ENOG4108K4C	ec 3.1.3.12
GA646_RS11850	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GA646_RS11855	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GA646_RS11865	ENOG4105C2W	permease
GA646_RS11875	ENOG4108IQI	permease
GA646_RS11885	ENOG4108WHA	ompa motb domain protein
GA646_RS11895	ENOG4105CHU	acetyl-coa acetyltransferase
GA646_RS11910	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GA646_RS11920	ENOG4108R6W	Transcriptional regulator, ARAC family
GA646_RS11925	ENOG4105CHU	acetyl-coa acetyltransferase
GA646_RS11930	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GA646_RS11950	ENOG4108UT2	hemolysin iii
GA646_RS11955	ENOG4105CSH	Transporter
GA646_RS11965	ENOG4105DIN	metallophosphoesterase
GA646_RS11970	ENOG4107RZC	phospholipase d
GA646_RS11980	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GA646_RS12010	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GA646_RS12015	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GA646_RS12020	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GA646_RS12030	ENOG4108UJD	30S ribosomal protein S9
GA646_RS12035	ENOG4107MKT	Stringent starvation protein a
GA646_RS12040	ENOG4105KB2	stringent starvation protein b
GA646_RS12115	ENOG4107QHF	type ii secretion system protein e
GA646_RS12135	ENOG4105C2M	dna polymerase I
GA646_RS12140	ENOG4108VIA	integral membrane protein
GA646_RS12145	ENOG4105II7	pyrroline-5-carboxylate reductase
GA646_RS12150	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GA646_RS12160	ENOG4105C9X	ppx gppa phosphatase
GA646_RS12170	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GA646_RS12185	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GA646_RS12205	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GA646_RS12220	ENOG4105W39	Membrane
GA646_RS12225	ENOG4105CYM	Glutathione S-transferase
GA646_RS12240	ENOG4105CEY	Amp-dependent synthetase and ligase
GA646_RS12245	ENOG4105N42	UPF0307 protein
GA646_RS12255	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GA646_RS12270	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GA646_RS12275	ENOG4105DJ0	Poly(A) Polymerase
GA646_RS12280	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GA646_RS12285	ENOG4105DXN	mazG family
GA646_RS12300	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GA646_RS12310	ENOG4105CUT	histidyl-tRNA synthetase
GA646_RS12320	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GA646_RS12340	ENOG4105WVQ	Fe-S assembly protein IscX
GA646_RS12390	ENOG4108ZP8	Acetolactate synthase small subunit
GA646_RS12395	ENOG4105C7K	acetolactate synthase
GA646_RS12445	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GA646_RS12450	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GA646_RS12455	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GA646_RS12465	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GA646_RS12475	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GA646_RS12480	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GA646_RS12490	ENOG4105VW4	glutaredoxin 3
GA646_RS12500	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS12505	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GA646_RS12515	ENOG4105FFC	UPF0187 protein
GA646_RS12520	ENOG4105DB7	PHP domain protein
GA646_RS12530	ENOG4105K9H	YciI-like protein
GA646_RS12550	ENOG4108VPT	UPF0234 protein
GA646_RS12560	ENOG4105NAU	thioesterase Superfamily protein
GA646_RS12575	ENOG4107QPB	Beta-lactamase domain protein
GA646_RS12620	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GA646_RS12625	ENOG4105D6S	protein involved in catabolism of external DNA
GA646_RS12665	ENOG4105E4C	Lytic transglycosylase catalytic
GA646_RS12670	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GA646_RS12675	ENOG4105C9A	Phoh family
GA646_RS12720	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GA646_RS12725	ENOG4107S2Z	UPF0761 membrane protein
GA646_RS12755	ENOG4105CIY	formyltetrahydrofolate deformylase
GA646_RS12760	ENOG41062JF	Transcriptional regulator
GA646_RS12765	ENOG4107RGH	Aldehyde dehydrogenase
GA646_RS12770	ENOG4105KDC	50s ribosomal protein l28
GA646_RS12775	ENOG4105W0E	50S ribosomal protein L33
GA646_RS12780	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GA646_RS12800	ENOG4105C4R	Atp-dependent dna helicase
GA646_RS12810	ENOG4105BZW	Glycerate kinase
GA646_RS12825	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GA646_RS12840	ENOG41069P5	Protein slyX homolog
GA646_RS12845	ENOG4105C5H	ABC transporter
GA646_RS12850	ENOG4105D1S	lipid A biosynthesis
GA646_RS12910	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GA646_RS12925	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GA646_RS12935	ENOG4105DUM	transcriptional regulator, lysR family
GA646_RS12955	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GA646_RS12960	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GA646_RS12985	ENOG4105CH6	catalase
GA646_RS13000	ENOG4105E5H	Transposase
GA646_RS13010	ENOG4105IYK	transposase
GA646_RS13015	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
GA646_RS13020	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
GA646_RS13025	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
GA646_RS13040	ENOG4105FUY	alpha subunit
GA646_RS13045	ENOG4108W5M	transcriptional regulator
GA646_RS13060	ENOG4105EPF	Outer membrane porin
GA646_RS13065	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
GA646_RS13070	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
GA646_RS13075	ENOG4105IKQ	hydratase
GA646_RS13080	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
GA646_RS13085	ENOG4105EI2	Pseudouridine synthase
GA646_RS13090	ENOG4105C03	ribonuclease
GA646_RS13120	ENOG41067S9	phage shock protein C, PspC
GA646_RS13135	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GA646_RS13160	ENOG4105C5I	Dehydrogenase
GA646_RS13175	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GA646_RS13185	ENOG4105BZ8	glutamate synthase
GA646_RS13195	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GA646_RS13205	ENOG4105C5X	domain protein
GA646_RS13220	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GA646_RS13230	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GA646_RS13240	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GA646_RS13245	ENOG4108JU5	Magnesium and cobalt efflux protein
GA646_RS13250	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GA646_RS13260	ENOG4108VAU	general secretion pathway protein G
GA646_RS13265	ENOG4105D7Q	type ii secretion system
GA646_RS13270	ENOG4105C25	Primosomal protein n'
GA646_RS13280	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GA646_RS13290	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
GA646_RS13295	ENOG4105Z2P	Protein of unknown function (DUF465)
GA646_RS13310	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GA646_RS13315	ENOG4105D7V	transposase
GA646_RS13320	ENOG4107QYX	exodeoxyribonuclease v alpha
GA646_RS13325	ENOG4107QKA	exodeoxyribonuclease V beta
GA646_RS13330	ENOG4105DSY	exodeoxyribonuclease V, gamma
GA646_RS13340	ENOG4105CSR	polyphosphate kinase 2
GA646_RS13350	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GA646_RS13360	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GA646_RS13370	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GA646_RS13385	ENOG4105D65	subunit l
GA646_RS13390	ENOG4108ZE9	Monovalent cation H antiporter subunit C
GA646_RS13395	ENOG4107R4Z	monovalent cation h antiporter subunit d
GA646_RS13400	ENOG4105SC1	monovalent cation H antiporter subunit E
GA646_RS13405	ENOG4105W4C	monovalent cation H antiporter subunit F
GA646_RS13410	ENOG4105KJM	monovalent cation h antiporter subunit g
GA646_RS13415	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GA646_RS13425	ENOG4105CHV	Transcription elongation factor NusA
GA646_RS13430	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GA646_RS13455	ENOG4107EJC	Preprotein translocase subunit SecG
GA646_RS13465	ENOG4107QHF	type ii secretion system protein e
GA646_RS13480	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GA646_RS13490	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GA646_RS13495	ENOG4105NBK	UPF0345 protein
GA646_RS13500	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GA646_RS13510	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GA646_RS13525	ENOG4105BZ1	(ABC) transporter
GA646_RS13530	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GA646_RS13545	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
GA646_RS13560	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GA646_RS13570	ENOG4105C2W	permease
GA646_RS13580	ENOG4107ZXU	DSBA oxidoreductase
GA646_RS13605	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GA646_RS13620	ENOG4105D3Y	Na H antiporter
GA646_RS13640	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GA646_RS13645	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GA646_RS13660	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GA646_RS13670	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GA646_RS13675	ENOG4105PM1	preprotein translocase subunit SecE
GA646_RS13715	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GA646_RS13725	ENOG4105GVR	general secretion pathway protein D
GA646_RS13740	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
GA646_RS13765	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GA646_RS13770	ENOG4108NEV	two component transcriptional regulator, LytTR family
GA646_RS13775	ENOG4108HRK	Histidine kinase
GA646_RS13790	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GA646_RS13810	ENOG41087AY	ADP-Ribose pyrophosphatase
GA646_RS13815	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GA646_RS13820	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GA646_RS13825	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GA646_RS13835	ENOG4105CNI	cell division protein FtsW
GA646_RS13850	ENOG4105CE1	Ferrous iron transport protein b
GA646_RS13860	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GA646_RS13865	ENOG4105T95	Thiol disulfide interChange protein
GA646_RS13870	ENOG4105D6E	homoserine dehydrogenase
GA646_RS13880	ENOG41061WM	D-Alanyl-D-Alanine
GA646_RS13890	ENOG4107TUY	Histidine kinase
GA646_RS13895	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GA646_RS13905	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GA646_RS13910	ENOG4108K5H	permease YjgP YjgQ family protein
GA646_RS13915	ENOG4108M8S	permease YjgP YjgQ family protein
GA646_RS13940	ENOG4105DQR	SNARE associated Golgi
GA646_RS13955	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GA646_RS13965	ENOG4105BZU	Histidine kinase
GA646_RS13980	ENOG4105C0P	Mg chelatase subunit ChlI
GA646_RS13990	ENOG4105EPF	Outer membrane porin
GA646_RS13995	ENOG4105F0N	pyrophosphate phospho-hydrolase
GA646_RS14010	ENOG4105CEY	Amp-dependent synthetase and ligase
GA646_RS14015	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GA646_RS14020	ENOG41079KZ	Major Facilitator Superfamily
GA646_RS14025	ENOG4105EN6	Membrane
GA646_RS14030	ENOG4105K5B	UPF0225 protein
GA646_RS14035	ENOG4105EE5	Membrane protein terC
GA646_RS14040	ENOG4108URH	decarboxylase
GA646_RS14060	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GA646_RS14075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GA646_RS14090	ENOG4105CCT	upf0313 protein
GA646_RS14095	ENOG4105D94	Major Facilitator Superfamily
GA646_RS14145	ENOG4105C79	DNA protecting protein DprA
GA646_RS14160	ENOG4108V06	Glutathione peroxidase
GA646_RS14170	ENOG4105EUB	pirin domain protein
GA646_RS14180	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GA646_RS14190	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GA646_RS14205	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GA646_RS14230	ENOG4105FDK	ABC transporter
GA646_RS14235	ENOG4105FAV	ABC, transporter
GA646_RS14240	ENOG410829K	Lysine exporter protein (Lyse ygga)
GA646_RS14245	ENOG4105EZR	dyp-type peroxidase family protein
GA646_RS14250	ENOG4107R1I	NAD-dependent malic enzyme
GA646_RS14280	ENOG4105EUB	pirin domain protein
GA646_RS14285	ENOG4105BZU	Histidine kinase
GA646_RS14290	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GA646_RS14295	ENOG4108VBZ	doxx family
GA646_RS14300	ENOG4105DQR	SNARE associated Golgi
GA646_RS14315	ENOG4107QJE	Chromosome Partitioning Protein
GA646_RS14325	ENOG4105M85	Bola protein
GA646_RS14360	ENOG4105ZTP	Protein of unknown function (DUF1376)
GA646_RS14440	ENOG4105KT5	UmuD protein
GA646_RS14470	ENOG4105ENX	hydrolase
GA646_RS14475	ENOG4107RTG	Major Facilitator superfamily
GA646_RS14485	ENOG4105DQ4	alcohol dehydrogenase
GA646_RS14495	ENOG4105EQ2	LysR family Transcriptional regulator
GA646_RS14585	ENOG4105C0D	helicase
GA646_RS14595	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
GA646_RS14605	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GA646_RS14610	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GA646_RS14620	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GA646_RS14625	ENOG4108ZAI	phosphatidylglycerophosphatase a
GA646_RS14635	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GA646_RS14650	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GA646_RS14655	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GA646_RS14665	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GA646_RS14670	ENOG4107WZ3	Transferase
GA646_RS14675	ENOG4105D3Q	Sugar transferase
GA646_RS14685	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GA646_RS14695	ENOG4105C5E	polysaccharide biosynthesis protein
GA646_RS14740	ENOG4108IJ1	Dehydrogenase
GA646_RS14745	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GA646_RS14750	ENOG4107QQG	Dehydrogenase
GA646_RS14755	ENOG4105DAY	polysaccharide export protein
GA646_RS14765	ENOG4105D75	Capsular exopolysaccharide family
GA646_RS14770	ENOG4108MRJ	
GA646_RS14805	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GA646_RS14820	ENOG4105C2W	permease
GA646_RS14835	ENOG4105C01	Dihydroxy-acid dehydratase
GA646_RS14845	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS14860	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GA646_RS14870	ENOG4105C8J	)-transporter
GA646_RS14875	ENOG4105C26	Dehydrogenase
GA646_RS14885	ENOG4108RS6	transposase
GA646_RS14895	ENOG4105D2S	major facilitator superfamily
GA646_RS14925	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GA646_RS14970	ENOG4105CVE	Lytic murein transglycosylase
GA646_RS14980	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GA646_RS14985	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GA646_RS15000	ENOG4105DFU	Cell wall formation (By similarity)
GA646_RS15010	ENOG4108RS6	transposase
GA646_RS15020	ENOG410830R	acetyltransferase
GA646_RS15030	ENOG4105DU1	integral membrane protein, terc
GA646_RS15035	ENOG4105VNT	transposase (IS4 family) protein
GA646_RS15040	ENOG4107QUY	Guanine deaminase
GA646_RS15045	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GA646_RS15055	ENOG4105T95	Thiol disulfide interChange protein
GA646_RS15085	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GA646_RS15090	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GA646_RS15095	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GA646_RS15100	ENOG4105VG0	50S ribosomal protein l34
GA646_RS15165	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
GA646_RS15190	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GA646_RS15220	ENOG4105F9F	transposase
GA646_RS15235	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GA646_RS15240	ENOG4105EPC	oxidoreductase
GA646_RS15325	ENOG4105MZU	cell filamentation protein
GA646_RS15360	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GA646_RS15370	ENOG4105E5H	Transposase
GA646_RS15385	ENOG4105E5H	Transposase
GA646_RS15400	ENOG4105E5H	Transposase
GA646_RS15460	ENOG4108C66	Inherit from COG: DNA primase
GA646_RS15500	ENOG4105E5H	Transposase
GA646_RS15595	ENOG4105E4P	ATPase (AAA