locus-tag	class	description
E5093_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E5093_RS00015	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E5093_RS00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E5093_RS00025	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E5093_RS00050	ENOG4105PGM	cation diffusion facilitator family transporter
E5093_RS00055	ENOG4105T95	Thiol disulfide interChange protein
E5093_RS00065	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E5093_RS00075	ENOG4107QUY	Guanine deaminase
E5093_RS00080	ENOG4105DU1	integral membrane protein, terc
E5093_RS00090	ENOG410830R	acetyltransferase
E5093_RS00100	ENOG4105DFU	Cell wall formation (By similarity)
E5093_RS00115	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E5093_RS00120	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E5093_RS00130	ENOG4105CVE	Lytic murein transglycosylase
E5093_RS00180	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E5093_RS00210	ENOG4105D2S	major facilitator superfamily
E5093_RS00220	ENOG4105C26	Dehydrogenase
E5093_RS00225	ENOG4105C8J	)-transporter
E5093_RS00235	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E5093_RS00250	ENOG4105C01	Dihydroxy-acid dehydratase
E5093_RS00270	ENOG4105C2W	permease
E5093_RS00280	ENOG4105J7D	transcriptional regulator
E5093_RS00285	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5093_RS00320	ENOG4108MRJ	
E5093_RS00325	ENOG4105D75	Capsular exopolysaccharide family
E5093_RS00335	ENOG4105DAY	polysaccharide export protein
E5093_RS00340	ENOG4107QQG	Dehydrogenase
E5093_RS00345	ENOG4107R5Z	Oxidoreductase domain protein
E5093_RS00350	ENOG4105J5G	Transferase hexapeptide repeat containing protein
E5093_RS00355	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5093_RS00385	ENOG4105D3Q	Sugar transferase
E5093_RS00390	ENOG4107WZ3	Transferase
E5093_RS00395	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5093_RS00405	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5093_RS00410	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5093_RS00420	ENOG4105CMR	udp-glucose 4-epimerase
E5093_RS00430	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E5093_RS00440	ENOG4108ZAI	phosphatidylglycerophosphatase a
E5093_RS00445	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E5093_RS00455	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E5093_RS00460	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E5093_RS00485	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
E5093_RS00530	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
E5093_RS00655	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E5093_RS00660	ENOG4105C3J	Cysteine desulfurase
E5093_RS00670	ENOG4105ZTP	Protein of unknown function (DUF1376)
E5093_RS00705	ENOG4105M85	Bola protein
E5093_RS00715	ENOG4107QJE	Chromosome Partitioning Protein
E5093_RS00730	ENOG4105DQR	SNARE associated Golgi
E5093_RS00735	ENOG4108VBZ	doxx family
E5093_RS00740	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5093_RS00750	ENOG4105EUB	pirin domain protein
E5093_RS00780	ENOG4107R1I	NAD-dependent malic enzyme
E5093_RS00785	ENOG4105CS6	Rhs element vgr protein
E5093_RS00800	ENOG4105EZR	dyp-type peroxidase family protein
E5093_RS00805	ENOG410829K	Lysine exporter protein (Lyse ygga)
E5093_RS00810	ENOG4105FAV	ABC, transporter
E5093_RS00815	ENOG4105FDK	ABC transporter
E5093_RS00865	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E5093_RS00885	ENOG4105EUB	pirin domain protein
E5093_RS00895	ENOG4108V06	Glutathione peroxidase
E5093_RS00910	ENOG4105C79	DNA protecting protein DprA
E5093_RS00960	ENOG4105D94	Major Facilitator Superfamily
E5093_RS00965	ENOG4105CCT	upf0313 protein
E5093_RS00980	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E5093_RS00995	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5093_RS01010	ENOG4108URH	decarboxylase
E5093_RS01015	ENOG4105EE5	Membrane protein terC
E5093_RS01020	ENOG4105K5B	UPF0225 protein
E5093_RS01025	ENOG4105EN6	Membrane
E5093_RS01030	ENOG41079KZ	Major Facilitator Superfamily
E5093_RS01035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5093_RS01040	ENOG4105CEY	Amp-dependent synthetase and ligase
E5093_RS01055	ENOG4105F0N	pyrophosphate phospho-hydrolase
E5093_RS01070	ENOG4105C0P	Mg chelatase subunit ChlI
E5093_RS01085	ENOG4105BZU	Histidine kinase
E5093_RS01095	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E5093_RS01110	ENOG4105DQR	SNARE associated Golgi
E5093_RS01135	ENOG4108M8S	permease YjgP YjgQ family protein
E5093_RS01140	ENOG4108K5H	permease YjgP YjgQ family protein
E5093_RS01145	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E5093_RS01155	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5093_RS01160	ENOG4107TUY	Histidine kinase
E5093_RS01170	ENOG41061WM	D-Alanyl-D-Alanine
E5093_RS01180	ENOG4105D6E	homoserine dehydrogenase
E5093_RS01185	ENOG4105T95	Thiol disulfide interChange protein
E5093_RS01190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5093_RS01200	ENOG4105CE1	Ferrous iron transport protein b
E5093_RS01215	ENOG4105CNI	cell division protein FtsW
E5093_RS01225	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E5093_RS01235	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E5093_RS01240	ENOG41087AY	ADP-Ribose pyrophosphatase
E5093_RS01260	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E5093_RS01275	ENOG4108HRK	Histidine kinase
E5093_RS01280	ENOG4108NEV	two component transcriptional regulator, LytTR family
E5093_RS01285	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E5093_RS01310	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
E5093_RS01325	ENOG4105GVR	general secretion pathway protein D
E5093_RS01335	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5093_RS01375	ENOG4105PM1	preprotein translocase subunit SecE
E5093_RS01380	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E5093_RS01390	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E5093_RS01405	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5093_RS01410	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5093_RS01430	ENOG4105D3Y	Na H antiporter
E5093_RS01445	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E5093_RS01475	ENOG4107ZXU	DSBA oxidoreductase
E5093_RS01485	ENOG4105C2W	permease
E5093_RS01495	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5093_RS01510	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
E5093_RS01525	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E5093_RS01530	ENOG4105BZ1	(ABC) transporter
E5093_RS01545	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E5093_RS01555	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E5093_RS01560	ENOG4105NBK	UPF0345 protein
E5093_RS01565	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E5093_RS01575	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E5093_RS01590	ENOG4107QHF	type ii secretion system protein e
E5093_RS01600	ENOG4107EJC	Preprotein translocase subunit SecG
E5093_RS01625	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E5093_RS01630	ENOG4105CHV	Transcription elongation factor NusA
E5093_RS01640	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E5093_RS01645	ENOG4105KJM	monovalent cation h antiporter subunit g
E5093_RS01650	ENOG4105W4C	monovalent cation H antiporter subunit F
E5093_RS01655	ENOG4105SC1	monovalent cation H antiporter subunit E
E5093_RS01660	ENOG4107R4Z	monovalent cation h antiporter subunit d
E5093_RS01665	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E5093_RS01670	ENOG4105D65	subunit l
E5093_RS01685	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E5093_RS01695	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E5093_RS01705	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E5093_RS01715	ENOG4105CSR	polyphosphate kinase 2
E5093_RS01725	ENOG4105DSY	exodeoxyribonuclease V, gamma
E5093_RS01730	ENOG4107QKA	exodeoxyribonuclease V beta
E5093_RS01735	ENOG4107QYX	exodeoxyribonuclease v alpha
E5093_RS01745	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E5093_RS01760	ENOG4105Z2P	Protein of unknown function (DUF465)
E5093_RS01765	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
E5093_RS01775	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E5093_RS01785	ENOG4105C25	Primosomal protein n'
E5093_RS01790	ENOG4105D7Q	type ii secretion system
E5093_RS01795	ENOG4108VAU	general secretion pathway protein G
E5093_RS01805	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E5093_RS01810	ENOG4108JU5	Magnesium and cobalt efflux protein
E5093_RS01815	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E5093_RS01820	ENOG4105CS6	Rhs element vgr protein
E5093_RS01845	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E5093_RS01855	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E5093_RS01870	ENOG4105C5X	domain protein
E5093_RS01880	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E5093_RS01890	ENOG4105BZ8	glutamate synthase
E5093_RS01900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E5093_RS01915	ENOG4105C5I	Dehydrogenase
E5093_RS01945	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E5093_RS01960	ENOG41067S9	phage shock protein C, PspC
E5093_RS01985	ENOG4105J5T	Amp-dependent synthetase and ligase
E5093_RS01990	ENOG4105C03	ribonuclease
E5093_RS01995	ENOG4105EI2	Pseudouridine synthase
E5093_RS02000	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
E5093_RS02005	ENOG4105IKQ	hydratase
E5093_RS02010	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
E5093_RS02015	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
E5093_RS02020	ENOG4105EPF	Outer membrane porin
E5093_RS02035	ENOG4108W5M	transcriptional regulator
E5093_RS02040	ENOG4105FUY	alpha subunit
E5093_RS02055	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
E5093_RS02060	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
E5093_RS02065	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
E5093_RS02080	ENOG4105CH6	catalase
E5093_RS02090	ENOG4105CSU	acyl-Coa dehydrogenase
E5093_RS02105	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E5093_RS02110	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5093_RS02130	ENOG4105DUM	transcriptional regulator, lysR family
E5093_RS02140	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5093_RS02155	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E5093_RS02205	ENOG4105D1S	lipid A biosynthesis
E5093_RS02210	ENOG4105C5H	ABC transporter
E5093_RS02230	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5093_RS02245	ENOG4105BZW	Glycerate kinase
E5093_RS02255	ENOG4105C4R	Atp-dependent dna helicase
E5093_RS02275	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5093_RS02290	ENOG4107RGH	Aldehyde dehydrogenase
E5093_RS02295	ENOG41062JF	Transcriptional regulator
E5093_RS02300	ENOG4105CIY	formyltetrahydrofolate deformylase
E5093_RS02330	ENOG4107S2Z	UPF0761 membrane protein
E5093_RS02335	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E5093_RS02380	ENOG4105C9A	Phoh family
E5093_RS02390	ENOG4105E4C	Lytic transglycosylase catalytic
E5093_RS02430	ENOG4105D6S	protein involved in catabolism of external DNA
E5093_RS02435	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E5093_RS02500	ENOG4105NAU	thioesterase Superfamily protein
E5093_RS02510	ENOG4108VPT	UPF0234 protein
E5093_RS02530	ENOG4105K9H	YciI-like protein
E5093_RS02540	ENOG4105DB7	PHP domain protein
E5093_RS02545	ENOG4105FFC	UPF0187 protein
E5093_RS02555	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E5093_RS02565	ENOG4105VW4	glutaredoxin 3
E5093_RS02575	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E5093_RS02580	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E5093_RS02590	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E5093_RS02595	ENOG4105CS6	Rhs element vgr protein
E5093_RS02615	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5093_RS02620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5093_RS02625	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5093_RS02650	ENOG4105C7K	acetolactate synthase
E5093_RS02655	ENOG4108ZP8	Acetolactate synthase small subunit
E5093_RS02695	ENOG4105WVQ	Fe-S assembly protein IscX
E5093_RS02715	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E5093_RS02725	ENOG4105CUT	histidyl-tRNA synthetase
E5093_RS02735	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5093_RS02750	ENOG4105DXN	mazG family
E5093_RS02755	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
E5093_RS02760	ENOG4105DJ0	Poly(A) Polymerase
E5093_RS02765	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5093_RS02780	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E5093_RS02790	ENOG4105N42	UPF0307 protein
E5093_RS02795	ENOG4105CEY	Amp-dependent synthetase and ligase
E5093_RS02810	ENOG4105CYM	Glutathione S-transferase
E5093_RS02815	ENOG4105W39	Membrane
E5093_RS02850	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E5093_RS02865	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E5093_RS02875	ENOG4105C9X	ppx gppa phosphatase
E5093_RS02885	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E5093_RS02890	ENOG4105II7	pyrroline-5-carboxylate reductase
E5093_RS02895	ENOG4108VIA	integral membrane protein
E5093_RS02900	ENOG4105C2M	dna polymerase I
E5093_RS02920	ENOG4107QHF	type ii secretion system protein e
E5093_RS02980	ENOG4105KB2	stringent starvation protein b
E5093_RS02985	ENOG4107MKT	Stringent starvation protein a
E5093_RS02990	ENOG4108UJD	30S ribosomal protein S9
E5093_RS03000	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E5093_RS03005	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E5093_RS03010	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E5093_RS03045	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E5093_RS03055	ENOG4107RZC	phospholipase d
E5093_RS03060	ENOG4105DIN	metallophosphoesterase
E5093_RS03070	ENOG4105CSH	Transporter
E5093_RS03075	ENOG4108UT2	hemolysin iii
E5093_RS03095	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5093_RS03100	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS03105	ENOG4108R6W	Transcriptional regulator, ARAC family
E5093_RS03115	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E5093_RS03130	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS03150	ENOG4108IQI	permease
E5093_RS03160	ENOG4105C2W	permease
E5093_RS03165	ENOG4105CI3	gtp-binding protein typa
E5093_RS03170	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E5093_RS03175	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E5093_RS03185	ENOG4108K4C	ec 3.1.3.12
E5093_RS03190	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E5093_RS03200	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E5093_RS03215	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5093_RS03230	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E5093_RS03235	ENOG4108I0Z	Aconitate hydratase
E5093_RS03260	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5093_RS03265	ENOG4105D3G	Pseudouridine synthase
E5093_RS03280	ENOG4105K78	MarR family Transcriptional regulator
E5093_RS03285	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E5093_RS03295	ENOG4105DSF	transport protein
E5093_RS03310	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E5093_RS03315	ENOG4105K56	Transcriptional regulator
E5093_RS03335	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5093_RS03355	ENOG4105HF0	Membrane
E5093_RS03365	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E5093_RS03370	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
E5093_RS03375	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E5093_RS03380	ENOG4108UWD	Iron-storage protein
E5093_RS03385	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5093_RS03395	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5093_RS03400	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5093_RS03410	ENOG4105FE9	pseudouridine synthase
E5093_RS03415	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E5093_RS03420	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E5093_RS03430	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E5093_RS03435	ENOG4108BPE	-transporting atpase
E5093_RS03440	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E5093_RS03450	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E5093_RS03455	ENOG4105CHR	reductase
E5093_RS03465	ENOG4109066	lysm domain bon superfamily protein
E5093_RS03475	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5093_RS03485	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5093_RS03490	ENOG4107EXC	regulatoR
E5093_RS03495	ENOG4105JJR	Histidine kinase
E5093_RS03500	ENOG4105CK7	Sodium proline symporter
E5093_RS03515	ENOG4105D78	K07001 NTE family protein
E5093_RS03530	ENOG4108UHE	carbonic anhydrase
E5093_RS03535	ENOG4105CDA	abc transporter atp-binding protein
E5093_RS03540	ENOG4105DRP	amino acid AbC transporter
E5093_RS03545	ENOG4105EAD	ABC transporter
E5093_RS03550	ENOG4107RP9	extracellular solute-binding protein, family 3
E5093_RS03555	ENOG4107VMU	Membrane
E5093_RS03570	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
E5093_RS03580	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E5093_RS03590	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
E5093_RS03595	ENOG4105K8R	UPF0145 protein
E5093_RS03600	ENOG4105K8R	UPF0145 protein
E5093_RS03610	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5093_RS03615	ENOG4105BZS	acriflavin resistance protein
E5093_RS03620	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E5093_RS03625	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E5093_RS03650	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E5093_RS03660	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E5093_RS03665	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5093_RS03670	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E5093_RS03675	ENOG4105CUB	amino acid
E5093_RS03690	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E5093_RS03700	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5093_RS03725	ENOG4107T5V	SNARE associated Golgi
E5093_RS03765	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E5093_RS03795	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E5093_RS03810	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E5093_RS03815	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5093_RS03820	ENOG4105C34	Pseudouridine synthase
E5093_RS03825	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E5093_RS03835	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E5093_RS03845	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E5093_RS03875	ENOG4105C4K	Nad synthetase
E5093_RS03890	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
E5093_RS03905	ENOG4105F95	Monooxygenase
E5093_RS03915	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E5093_RS03920	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E5093_RS03930	ENOG4105E33	succinate dehydrogenase
E5093_RS03935	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E5093_RS03940	ENOG4105C7S	Dehydrogenase
E5093_RS03945	ENOG4107QN2	dihydrolipoyl dehydrogenase
E5093_RS03955	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E5093_RS03965	ENOG4107BJW	polysaccharide deacetylase
E5093_RS03970	ENOG4105CND	Glycosyl transferase, family 2
E5093_RS03980	ENOG4107S78	Band 7 protein
E5093_RS03995	ENOG4105CKW	Inner membrane protein yedI
E5093_RS04000	ENOG4105CGZ	zinc metallopeptidase
E5093_RS04010	ENOG4108YV4	Universal stress protein
E5093_RS04015	ENOG4105EQK	-acetyltransferase
E5093_RS04020	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E5093_RS04030	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E5093_RS04035	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E5093_RS04050	ENOG4105HBR	Rna-binding protein
E5093_RS04060	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E5093_RS04070	ENOG4105EEI	dihydropteroate synthase
E5093_RS04105	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E5093_RS04150	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
E5093_RS04155	ENOG4105BZS	acriflavin resistance protein
E5093_RS04160	ENOG4105CJW	magnesium transporter
E5093_RS04170	ENOG4105D0M	Protease HtpX homolog
E5093_RS04175	ENOG4105E4C	Lytic transglycosylase catalytic
E5093_RS04180	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E5093_RS04190	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E5093_RS04195	ENOG4108RRZ	Transcription elongation factor GreB
E5093_RS04265	ENOG4105F5W	AtP-binding protein
E5093_RS04270	ENOG4105D70	Integrase catalytic subunit
E5093_RS04295	ENOG4105DDI	hemolysin-type calcium-binding region
E5093_RS04310	ENOG4108ZXE	
E5093_RS04360	ENOG4107QKW	extracellular solute-binding protein family 1
E5093_RS04365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5093_RS04370	ENOG4105C2I	pirin domain protein
E5093_RS04380	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E5093_RS04385	ENOG4105NX3	Membrane
E5093_RS04400	ENOG4105BZU	Histidine kinase
E5093_RS04415	ENOG4105EUJ	GTP cyclohydrolase i
E5093_RS04435	ENOG4105DDQ	anthranilate synthase
E5093_RS04450	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E5093_RS04495	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5093_RS04500	ENOG4107QNR	UPF0135 protein
E5093_RS04505	ENOG4105C0H	protease
E5093_RS04515	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E5093_RS04520	ENOG4105BZG	amino acid carrier protein
E5093_RS04525	ENOG4105C85	amino acid
E5093_RS04535	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E5093_RS04550	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5093_RS04560	ENOG4108YXU	transcriptional regulator AsnC family
E5093_RS04565	ENOG4105N14	lysine exporter protein LysE YggA
E5093_RS04570	ENOG4105BZJ	Electron transfer flavoprotein
E5093_RS04575	ENOG4105C10	Electron transfer flavoprotein
E5093_RS04585	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5093_RS04610	ENOG4108UPT	UPF0178 protein
E5093_RS04625	ENOG4105D60	lipoprotein releasing system transmembrane protein
E5093_RS04630	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5093_RS04635	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
E5093_RS04655	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E5093_RS04660	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E5093_RS04665	ENOG4105C02	permease
E5093_RS04670	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E5093_RS04715	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E5093_RS04720	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E5093_RS04730	ENOG4105M8F	Biopolymer transport protein exbD tolR
E5093_RS04735	ENOG4105E02	MotA TolQ exbB proton channel
E5093_RS04740	ENOG4107YD3	Thioesterase
E5093_RS04750	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E5093_RS04770	ENOG4108ETH	Formylglycinamide ribotide synthetase
E5093_RS04790	ENOG4105CGU	Enoyl-CoA hydratase
E5093_RS04800	ENOG4108YYC	ycei family
E5093_RS04805	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E5093_RS04815	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5093_RS04825	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E5093_RS04830	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E5093_RS04850	ENOG4107R11	Transcriptional regulator
E5093_RS04855	ENOG4108IJ6	ABC transporter
E5093_RS04865	ENOG4108I5D	sulfate abc transporter
E5093_RS04875	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E5093_RS04885	ENOG4105HHA	aminodeoxychorismate lyase
E5093_RS04900	ENOG4107VXZ	Hydrolase
E5093_RS04905	ENOG4108IYU	L-aspartate oxidase
E5093_RS04910	ENOG4105C0H	protease
E5093_RS04925	ENOG4105C3F	Signal peptidase i
E5093_RS04935	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E5093_RS04940	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E5093_RS04950	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E5093_RS04955	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E5093_RS04960	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E5093_RS04995	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E5093_RS05005	ENOG4105DTR	rard protein
E5093_RS05025	ENOG4105ECR	NmrA family
E5093_RS05030	ENOG4105KVH	Transcriptional regulator
E5093_RS05035	ENOG4105EQ0	Major Facilitator superfamily
E5093_RS05045	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E5093_RS05080	ENOG4105CDU	Replicative dna helicase
E5093_RS05090	ENOG41080IJ	Diacylglycerol kinase
E5093_RS05100	ENOG4105DHQ	Histidine kinase
E5093_RS05105	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5093_RS05110	ENOG4105DIJ	Phosphoethanolamine transferase
E5093_RS05170	ENOG4108JPW	Aminotransferase
E5093_RS05175	ENOG4105DY8	decarboxylase
E5093_RS05185	ENOG4105C8U	phosphate abc transporter
E5093_RS05195	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E5093_RS05200	ENOG4105ERU	peptidase
E5093_RS05210	ENOG4107QTF	adenylosuccinate lyase
E5093_RS05255	ENOG4108Z0R	Transferase
E5093_RS05260	ENOG4105DZ1	carboxypeptidase
E5093_RS05275	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E5093_RS05280	ENOG4108K5P	(LipO)protein
E5093_RS05285	ENOG4105EJC	lysr family transcriptional regulator
E5093_RS05290	ENOG4105C8Y	Acetylornithine aminotransferase
E5093_RS05295	ENOG4105M2J	Glutaredoxin
E5093_RS05300	ENOG4105DAN	ATP-dependent protease
E5093_RS05315	ENOG4105DHU	Bile acid
E5093_RS05335	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E5093_RS05340	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E5093_RS05345	ENOG4105D22	carbon starvation protein
E5093_RS05350	ENOG4105VCD	cytoplasmic protein
E5093_RS05355	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5093_RS05365	ENOG4105F8C	transglutaminase domain-containing protein
E5093_RS05385	ENOG4105C7N	Xanthine uracil vitamin C permease
E5093_RS05390	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E5093_RS05400	ENOG4105C3Q	Glycosyl transferase, family 2
E5093_RS05410	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5093_RS05420	ENOG4105CFH	Aspartokinase
E5093_RS05430	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E5093_RS05445	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E5093_RS05450	ENOG4108K0D	peptidase, M48
E5093_RS05465	ENOG4105CPC	Aldo Keto reductase
E5093_RS05470	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E5093_RS05475	ENOG4108UKZ	OsmC family
E5093_RS05480	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5093_RS05505	ENOG4105CXT	aspartate transcarbamylase
E5093_RS05510	ENOG4105CD3	dihydroorotase
E5093_RS05515	ENOG4105CDV	Ompa motb domain protein
E5093_RS05520	ENOG4107QNJ	CoA-transferase subunit B
E5093_RS05530	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E5093_RS05540	ENOG4105E39	Enoyl-CoA hydratase
E5093_RS05545	ENOG4107QX3	carboxylase
E5093_RS05550	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS05555	ENOG4108SGK	Tetr family transcriptional regulator
E5093_RS05560	ENOG4105CEY	Amp-dependent synthetase and ligase
E5093_RS05580	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E5093_RS05590	ENOG4105CHH	sulfate transporter
E5093_RS05595	ENOG4108K3A	Glutathione S-transferase
E5093_RS05610	ENOG4105M08	Membrane
E5093_RS05615	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5093_RS05625	ENOG4105VEQ	Cold shock protein
E5093_RS05630	ENOG4105C1J	atp-dependent rna helicase
E5093_RS05675	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E5093_RS05690	ENOG4105C5I	Dehydrogenase
E5093_RS05695	ENOG4105ERG	peptidase m48, ste24p
E5093_RS05710	ENOG4105KTH	gatB Yqey
E5093_RS05740	ENOG4105D9P	serine threonine protein kinase
E5093_RS05785	ENOG4105CHM	Aminotransferase
E5093_RS05790	ENOG4105E0X	reductase
E5093_RS05795	ENOG4108V06	Glutathione peroxidase
E5093_RS05805	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E5093_RS05815	ENOG4105ZED	uncharacterized protein ygaH
E5093_RS05820	ENOG4108UMN	azlc family
E5093_RS05830	ENOG4105C3G	gtp-binding protein
E5093_RS05855	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E5093_RS05895	ENOG4105BZU	Histidine kinase
E5093_RS05900	ENOG4105BZU	Histidine kinase
E5093_RS05910	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E5093_RS05925	ENOG4107HP6	Transcriptional regulator
E5093_RS05930	ENOG4107QP7	CoA-transferase subunit A
E5093_RS05935	ENOG4107QNJ	CoA-transferase subunit B
E5093_RS05940	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS05945	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E5093_RS05950	ENOG4105F2Z	3-oxoadipate enol-lactonase
E5093_RS05980	ENOG4105VT2	5-hydroxyisourate hydrolase
E5093_RS05995	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
E5093_RS06000	ENOG4105E09	nadh pyrophosphatase
E5093_RS06025	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E5093_RS06040	ENOG4105DHQ	Histidine kinase
E5093_RS06045	ENOG4105ETX	regulatoR
E5093_RS06060	ENOG4108MGI	Transcriptional regulator
E5093_RS06075	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E5093_RS06105	ENOG4105CNM	Receptor
E5093_RS06115	ENOG4105M8F	Biopolymer transport protein exbD tolR
E5093_RS06120	ENOG4105E02	MotA TolQ exbB proton channel
E5093_RS06125	ENOG4107T32	3-phytase (EC 3.1.3.8)
E5093_RS06135	ENOG4105BZU	Histidine kinase
E5093_RS06155	ENOG4105DNH	Major Facilitator
E5093_RS06160	ENOG4105DXM	phenylacetic acid degradation protein
E5093_RS06165	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
E5093_RS06170	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
E5093_RS06175	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
E5093_RS06180	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
E5093_RS06185	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5093_RS06190	ENOG4105E39	Enoyl-CoA hydratase
E5093_RS06195	ENOG4108UKI	Enoyl-CoA hydratase
E5093_RS06200	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5093_RS06205	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS06210	ENOG4105DZS	Phenylacetate-CoA ligase
E5093_RS06215	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
E5093_RS06225	ENOG4105CEY	Amp-dependent synthetase and ligase
E5093_RS06245	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E5093_RS06250	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E5093_RS06255	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E5093_RS06270	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
E5093_RS06285	ENOG4105N0V	mono-oxygenase ydhR
E5093_RS06290	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E5093_RS06295	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E5093_RS06305	ENOG4108YYC	ycei family
E5093_RS06310	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5093_RS06320	ENOG4107RR1	TRANSCRIPTIONal
E5093_RS06340	ENOG4107QUV	Domain protein
E5093_RS06345	ENOG4105DZ2	Transcriptional regulator
E5093_RS06355	ENOG4108VMM	UPF0756 membrane protein
E5093_RS06360	ENOG4105I08	Pseudouridine synthase
E5093_RS06380	ENOG4105K8N	protein family UPF0079, ATPase
E5093_RS06385	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E5093_RS06395	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E5093_RS06400	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E5093_RS06405	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E5093_RS06410	ENOG4105EHM	Aminoglycoside phosphotransferase
E5093_RS06415	ENOG4108S0S	Nucleotidyl transferase
E5093_RS06425	ENOG4107QJE	Chromosome Partitioning Protein
E5093_RS06430	ENOG4105FA0	parb-like partition protein
E5093_RS06445	ENOG4105BZ1	(ABC) transporter
E5093_RS06450	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E5093_RS06460	ENOG4107QRG	dna polymerase iii
E5093_RS06470	ENOG4105F8V	Hydrolase, tatD family
E5093_RS06495	ENOG4108RTD	type II secretion system protein K
E5093_RS06505	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E5093_RS06515	ENOG4108Z6B	deaminase
E5093_RS06530	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E5093_RS06535	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E5093_RS06545	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E5093_RS06550	ENOG4105DWU	Membrane
E5093_RS06555	ENOG4107RN6	Monooxygenase
E5093_RS06565	ENOG4105D6Z	AFG1 family ATPase
E5093_RS06570	ENOG4107QP3	malate synthase g
E5093_RS06590	ENOG4105EE5	Membrane protein terC
E5093_RS06610	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5093_RS06615	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E5093_RS06620	ENOG4105CC0	LysR family Transcriptional regulator
E5093_RS06630	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5093_RS06635	ENOG4105CUX	Signal transduction histidine kinase
E5093_RS06650	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E5093_RS06655	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E5093_RS06660	ENOG4105KNE	Phosphatidate cytidylyltransferase
E5093_RS06670	ENOG4105DZP	Membrane-associated zinc metalloprotease
E5093_RS06675	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5093_RS06695	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5093_RS06725	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5093_RS06735	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5093_RS06740	ENOG4105E7U	AraC family transcriptional regulator
E5093_RS06745	ENOG4105EEF	Alkane 1-monooxygenase
E5093_RS06750	ENOG4108MJ3	acetyltransferase
E5093_RS06755	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS06760	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS06780	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E5093_RS06800	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5093_RS06805	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5093_RS06815	ENOG4105PV3	Inner membrane protein yqiJ
E5093_RS06840	ENOG4105HDD	phospholipase
E5093_RS06845	ENOG4105CZN	Potassium uptake protein
E5093_RS06855	ENOG4105C7B	Threonine dehydratase
E5093_RS06860	ENOG4105E66	phosphoriboisomerase A
E5093_RS06880	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E5093_RS06885	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5093_RS06915	ENOG4105CR4	methylisocitrate lyase
E5093_RS06920	ENOG4105BZN	citrate synthase
E5093_RS06930	ENOG4105CEV	competence damage-inducible protein
E5093_RS06965	ENOG4105D8G	Major Facilitator superfamily
E5093_RS06980	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E5093_RS06985	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E5093_RS07020	ENOG4105EV9	Alpha Beta Hydrolase
E5093_RS07050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5093_RS07110	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E5093_RS07115	ENOG4105C26	Dehydrogenase
E5093_RS07125	ENOG4105ETS	cytosine purines uracil thiamine allantoin
E5093_RS07130	ENOG4105C26	Dehydrogenase
E5093_RS07135	ENOG4108M8W	Monooxygenase
E5093_RS07140	ENOG4105MXW	flavin reductase domain protein, FMN-binding
E5093_RS07145	ENOG4108MXF	Alpha Beta Hydrolase
E5093_RS07170	ENOG4105HF0	Membrane
E5093_RS07175	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E5093_RS07190	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E5093_RS07195	ENOG4107QX9	Thiol disulfide interChange protein
E5093_RS07200	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E5093_RS07210	ENOG4105DHQ	Histidine kinase
E5093_RS07225	ENOG4105C26	Dehydrogenase
E5093_RS07230	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
E5093_RS07235	ENOG4105C94	Transporter
E5093_RS07265	ENOG4107KET	secretion protein, HlyD family
E5093_RS07295	ENOG4105CEY	Amp-dependent synthetase and ligase
E5093_RS07305	ENOG4108IPT	Naphthoate synthase
E5093_RS07315	ENOG4108U05	Transcriptional regulator
E5093_RS07320	ENOG4107RGD	Major Facilitator superfamily
E5093_RS07335	ENOG4105CEY	Amp-dependent synthetase and ligase
E5093_RS07350	ENOG4107RN6	Monooxygenase
E5093_RS07355	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5093_RS07360	ENOG4105CSU	acyl-Coa dehydrogenase
E5093_RS07365	ENOG4105EA8	2-Nitropropane dioxygenase
E5093_RS07370	ENOG4108UKI	Enoyl-CoA hydratase
E5093_RS07375	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
E5093_RS07380	ENOG4105MP9	class II Aldolase
E5093_RS07390	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS07395	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5093_RS07400	ENOG4105E39	Enoyl-CoA hydratase
E5093_RS07405	ENOG4107RGD	Major Facilitator superfamily
E5093_RS07425	ENOG4107QNJ	CoA-transferase subunit B
E5093_RS07430	ENOG4107QP7	CoA-transferase subunit A
E5093_RS07435	ENOG4107RGD	Major Facilitator superfamily
E5093_RS07440	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS07445	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS07455	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E5093_RS07465	ENOG4105TMB	Formate nitrite transporter
E5093_RS07470	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
E5093_RS07480	ENOG4106UW1	Major Facilitator superfamily
E5093_RS07520	ENOG4105D2S	major facilitator superfamily
E5093_RS07525	ENOG4108KB2	LysR family Transcriptional regulator
E5093_RS07530	ENOG4105DTQ	mandelate racemase muconate lactonizing
E5093_RS07535	ENOG4105NN7	muconolactone delta-isomerase
E5093_RS07545	ENOG4105FUY	alpha subunit
E5093_RS07550	ENOG4108UKV	benzoate 1,2-dioxygenase
E5093_RS07555	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
E5093_RS07560	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
E5093_RS07565	ENOG4105DKK	Benzoate
E5093_RS07570	ENOG4107QP7	CoA-transferase subunit A
E5093_RS07575	ENOG4107QNJ	CoA-transferase subunit B
E5093_RS07580	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS07585	ENOG4105F2Z	3-oxoadipate enol-lactonase
E5093_RS07605	ENOG4105DDW	LysR family Transcriptional regulator
E5093_RS07610	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E5093_RS07615	ENOG4105E0C	molybdate abc transporter
E5093_RS07620	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E5093_RS07625	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E5093_RS07630	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E5093_RS07660	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E5093_RS07665	ENOG4107QZF	nitrite reductase NADPH large subunit
E5093_RS07670	ENOG4107RNU	major facilitator superfamily MFS_1
E5093_RS07685	ENOG4105C6T	cysteine synthase
E5093_RS07690	ENOG4105E55	glycerol-3-phosphate acyltransferase
E5093_RS07695	ENOG41080HT	Transcriptional regulator, arsr family
E5093_RS07715	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
E5093_RS07720	ENOG4105CUY	Mechanosensitive ion channel
E5093_RS07740	ENOG4105BZ1	(ABC) transporter
E5093_RS07750	ENOG4108ZX5	transcriptional regulator
E5093_RS07760	ENOG4105CZM	Major Facilitator
E5093_RS07765	ENOG4105CZX	twitching motility protein
E5093_RS07770	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5093_RS07780	ENOG4105C85	amino acid
E5093_RS07785	ENOG4105CGF	Aromatic amino acid aminotransferase
E5093_RS07790	ENOG4105BZU	Histidine kinase
E5093_RS07800	ENOG4107RZC	phospholipase d
E5093_RS07840	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS07850	ENOG4105KK6	nuclease
E5093_RS07860	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5093_RS07865	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5093_RS07870	ENOG41065XD	Transcriptional regulator
E5093_RS07875	ENOG4105CZM	Major Facilitator
E5093_RS07880	ENOG4105CF7	AraC family transcriptional regulator
E5093_RS07885	ENOG4105CSU	acyl-Coa dehydrogenase
E5093_RS07905	ENOG4105X58	receptor
E5093_RS07920	ENOG4105CMR	udp-glucose 4-epimerase
E5093_RS07945	ENOG4105CMU	LysR family (Transcriptional regulator
E5093_RS07955	ENOG41067MG	lrgb family
E5093_RS07960	ENOG4108Z66	YbaK ebsC protein
E5093_RS07975	ENOG4107RKG	DJ-1/PfpI family
E5093_RS08020	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E5093_RS08060	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E5093_RS08090	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E5093_RS08100	ENOG4105C28	cystathionine
E5093_RS08120	ENOG4105K59	histidine triad (HIT) protein
E5093_RS08145	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E5093_RS08150	ENOG4105K70	DNA-binding protein
E5093_RS08165	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E5093_RS08175	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E5093_RS08180	ENOG4108Z4V	iron-sulfur cluster assembly
E5093_RS08195	ENOG4108ZIT	Ferredoxin, 2FE-2S
E5093_RS08200	ENOG4105F8J	Adenylate Guanylate cyclase
E5093_RS08210	ENOG4108JA2	transcriptioN-repair coupling factor
E5093_RS08225	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E5093_RS08230	ENOG4105K4T	epimerase
E5093_RS08235	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E5093_RS08250	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E5093_RS08255	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E5093_RS08260	ENOG4105VEJ	Heat shock protein
E5093_RS08270	ENOG4105Y3E	Modulates RecA activity (By similarity)
E5093_RS08285	ENOG4105CNI	cell division protein FtsW
E5093_RS08295	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E5093_RS08300	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E5093_RS08330	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5093_RS08345	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E5093_RS08360	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS08365	ENOG4105W8I	Transcriptional regulator
E5093_RS08370	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E5093_RS08375	ENOG4108IJ0	Aspartate ammonia-lyase
E5093_RS08380	ENOG4105CK7	Sodium proline symporter
E5093_RS08385	ENOG4105EW9	transcriptional regulator AsnC family
E5093_RS08390	ENOG4105C26	Dehydrogenase
E5093_RS08410	ENOG4108T58	Mg2 transport protein CorA
E5093_RS08435	ENOG4105CNV	Aldolase
E5093_RS08440	ENOG4108RCM	Nitroreductase
E5093_RS08450	ENOG4108TZV	Membrane
E5093_RS08455	ENOG4105D2N	Aldolase
E5093_RS08475	ENOG4108UHJ	MAF-like protein
E5093_RS08480	ENOG4105EZE	Cupin 4 family protein
E5093_RS08485	ENOG4105BZU	Histidine kinase
E5093_RS08495	ENOG4105CBC	glutamate synthase
E5093_RS08515	ENOG4105KJF	protein tyrosine phosphatase
E5093_RS08520	ENOG4105C0A	alcohol dehydrogenase
E5093_RS08530	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E5093_RS08550	ENOG4105CHR	reductase
E5093_RS08555	ENOG4105CHU	acetyl-coa acetyltransferase
E5093_RS08565	ENOG4105EVZ	LysR family transcriptional regulator
E5093_RS08570	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5093_RS08575	ENOG4108NIW	Leucine export protein LeuE
E5093_RS08580	ENOG4105DKK	Benzoate
E5093_RS08590	ENOG41081QV	Universal stress protein
E5093_RS08605	ENOG4105CD8	aminopeptidase N
E5093_RS08635	ENOG4105D6U	Sodium Glutamate Symporter
E5093_RS08650	ENOG4107QIJ	Aconitate hydratase 2
E5093_RS08675	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
E5093_RS08690	ENOG4105KRF	dihydroneopterin aldolase
E5093_RS08700	ENOG4105D06	uba thif-type nad fad binding protein
E5093_RS08715	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS08735	ENOG4105FFC	UPF0187 protein
E5093_RS08740	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E5093_RS08745	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E5093_RS08760	ENOG4105DEN	Luciferase family
E5093_RS08785	ENOG4105E2S	oxidase) subunit II
E5093_RS08790	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E5093_RS08795	ENOG4105CCU	oxidase (Subunit III)
E5093_RS08800	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E5093_RS08815	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E5093_RS08825	ENOG4105CDU	Replicative dna helicase
E5093_RS08830	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5093_RS08895	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E5093_RS08900	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E5093_RS08905	ENOG4105C12	Phosphoribosylglycinamide synthetase
E5093_RS08915	ENOG4105D01	(LipO)protein
E5093_RS08920	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E5093_RS08925	ENOG4108UMI	ABC transporter, permease
E5093_RS08930	ENOG4105C0B	DNA polymerase III (alpha subunit)
E5093_RS08970	ENOG4108Z4U	Ferredoxin
E5093_RS09000	ENOG4107QZV	Type I secretion membrane fusion protein
E5093_RS09005	ENOG4108JJA	ABC, transporter
E5093_RS09010	ENOG4105DFG	type I secretion outer membrane protein
E5093_RS09015	ENOG4108IUZ	ABC transporter
E5093_RS09020	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E5093_RS09035	ENOG4105C2X	Arabinose 5-phosphate isomerase
E5093_RS09060	ENOG4105CQ7	ATP-dependent helicase
E5093_RS09065	ENOG4105D3R	alkyl hydroperoxide reductase
E5093_RS09090	ENOG4108JU3	Alkyl hydroperoxide reductase
E5093_RS09100	ENOG41066VF	YeeE YedE family protein
E5093_RS09125	ENOG4105EA8	2-Nitropropane dioxygenase
E5093_RS09135	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5093_RS09140	ENOG4105VEQ	Cold shock protein
E5093_RS09155	ENOG4107QS8	(LipO)protein
E5093_RS09190	ENOG4105X0D	Fimbrial protein
E5093_RS09205	ENOG4105EJ2	Transcriptional regulator
E5093_RS09210	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
E5093_RS09220	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E5093_RS09225	ENOG4105D3G	Pseudouridine synthase
E5093_RS09250	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E5093_RS09290	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E5093_RS09295	ENOG4108MEJ	flavin reductase domain protein
E5093_RS09305	ENOG4105FAA	peptidase M23
E5093_RS09320	ENOG4108R99	pseudouridine synthase
E5093_RS09335	ENOG4105DZ1	carboxypeptidase
E5093_RS09340	ENOG4105CEP	NADH dehydrogenase
E5093_RS09345	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E5093_RS09370	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E5093_RS09375	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E5093_RS09380	ENOG4105CQC	Prephenate dehydratase
E5093_RS09390	ENOG4107R7Y	intracellular protease Pfpi family
E5093_RS09395	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS09400	ENOG4105CK2	sodium dicarboxylate symporter
E5093_RS09410	ENOG4105VUT	cytoplasmic protein
E5093_RS09415	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E5093_RS09420	ENOG4105BZ4	penicillin-binding protein
E5093_RS09440	ENOG4105DHQ	Histidine kinase
E5093_RS09445	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5093_RS09455	ENOG4107QHF	type ii secretion system protein e
E5093_RS09465	ENOG4108R96	Methyltransferase, YaeB family
E5093_RS09470	ENOG4105DP0	ferredoxin-NADP reductase
E5093_RS09485	ENOG4105CAU	Arsenical resistance protein, ArsH
E5093_RS09490	ENOG4105D6J	arsenicaL-resistance protein
E5093_RS09500	ENOG41082YX	Transcriptional regulator, arsr family
E5093_RS09510	ENOG4105CFP	Peptidase U32
E5093_RS09515	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E5093_RS09520	ENOG4108JU3	Alkyl hydroperoxide reductase
E5093_RS09540	ENOG4105NXH	GreA GreB family elongation factor
E5093_RS09545	ENOG4105VNT	transposase (IS4 family) protein
E5093_RS09710	ENOG4108TFU	terminase (Small subunit)
E5093_RS09850	ENOG4105DA5	(ABC) transporter
E5093_RS09855	ENOG4105E3A	(ABC) transporter
E5093_RS09870	ENOG4105CVE	Lytic murein transglycosylase
E5093_RS09895	ENOG4105CE9	30S ribosomal protein S2
E5093_RS09900	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E5093_RS09925	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5093_RS09955	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E5093_RS09960	ENOG4105SYT	Methylenetetrahydrofolate reductase
E5093_RS09965	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E5093_RS09970	ENOG4105BZU	Histidine kinase
E5093_RS09975	ENOG4105C6K	Malic enzyme
E5093_RS09985	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
E5093_RS10015	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
E5093_RS10035	ENOG4105DFP	Integrase
E5093_RS10060	ENOG4105EYM	Major Facilitator superfamily
E5093_RS10130	ENOG4105D6J	arsenicaL-resistance protein
E5093_RS10140	ENOG41082YX	Transcriptional regulator, arsr family
E5093_RS10165	ENOG4105CVR	type I restriction-modification system
E5093_RS10215	ENOG4105W1Y	Transcriptional regulator
E5093_RS10235	ENOG4105W1Y	Transcriptional regulator
E5093_RS10280	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5093_RS10300	ENOG4105EKE	dihydroorotase
E5093_RS10305	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E5093_RS10330	ENOG4108IQI	permease
E5093_RS10360	ENOG4108JQ5	ABC transporter
E5093_RS10365	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E5093_RS10370	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E5093_RS10375	ENOG4105E43	Extracellular solute-binding protein, family 5
E5093_RS10380	ENOG4105E9H	Lytic Murein transglycosylase
E5093_RS10385	ENOG4107RZZ	dna polymerase iii epsilon subunit
E5093_RS10395	ENOG4105E09	nadh pyrophosphatase
E5093_RS10400	ENOG4105EBR	Carboxylesterase
E5093_RS10405	ENOG4105W4M	Transport-associated protein
E5093_RS10415	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E5093_RS10420	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E5093_RS10430	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E5093_RS10435	ENOG4105D0A	hydroxylase
E5093_RS10440	ENOG4107RAQ	aminopeptidase
E5093_RS10445	ENOG4105E07	UPF0149 protein
E5093_RS10475	ENOG4105CXG	d-lactate dehydrogenase
E5093_RS10485	ENOG41073TP	transcriptional regulator
E5093_RS10490	ENOG4105DAA	L-lactate
E5093_RS10505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E5093_RS10515	ENOG4107VAM	peptidase, m28
E5093_RS10525	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E5093_RS10535	ENOG4105D82	Glutamate dehydrogenase
E5093_RS10540	ENOG4108R3D	Electron transport complex
E5093_RS10545	ENOG4105CSM	endonuclease III
E5093_RS10570	ENOG4105CJN	penicillin-binding protein
E5093_RS10575	ENOG4106H78	methyltransferase
E5093_RS10590	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E5093_RS10605	ENOG4105CQM	Urea amidohydrolase subunit alpha
E5093_RS10625	ENOG4105CHR	reductase
E5093_RS10635	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E5093_RS10640	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
E5093_RS10650	ENOG4107RET	Isocitrate lyase
E5093_RS10660	ENOG4105C37	(CBS) domain
E5093_RS10690	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E5093_RS10715	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E5093_RS10720	ENOG4105VCQ	rubredoxin
E5093_RS10725	ENOG4107QZF	nitrite reductase NADPH large subunit
E5093_RS10735	ENOG4105C5Q	Transcriptional regulator
E5093_RS10745	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E5093_RS10750	ENOG4107U91	Rhomboid family
E5093_RS10755	ENOG4105CV6	ABC transporter, permease
E5093_RS10760	ENOG4108I0Y	(ABC) transporter
E5093_RS10765	ENOG4108UJV	acyl-CoA thioesterase i
E5093_RS10785	ENOG4105D05	Receptor
E5093_RS10810	ENOG4105CJ3	phosphate transporter
E5093_RS10815	ENOG4105C3R	Methionine synthase
E5093_RS10835	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
E5093_RS10840	ENOG4105CSV	Glutaminase
E5093_RS10850	ENOG4105CSH	Transporter
E5093_RS10880	ENOG4105BZU	Histidine kinase
E5093_RS10890	ENOG4108VWS	Yaeq family
E5093_RS10895	ENOG4105CKI	cobalamin synthesis protein
E5093_RS10915	ENOG4108W5M	transcriptional regulator
E5093_RS10920	ENOG4105CZM	Major Facilitator
E5093_RS10930	ENOG4108S4H	thioesterase Superfamily protein
E5093_RS10940	ENOG4105D78	K07001 NTE family protein
E5093_RS10945	ENOG4105FGV	Chromate
E5093_RS10950	ENOG4105BZG	amino acid carrier protein
E5093_RS10955	ENOG4105D6U	Sodium Glutamate Symporter
E5093_RS10970	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5093_RS10975	ENOG4105EM2	membrane
E5093_RS10985	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E5093_RS11040	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
E5093_RS11045	ENOG4105WD1	Membrane
E5093_RS11055	ENOG4106BSU	Entericidin B
E5093_RS11075	ENOG4105C8Q	Methyl-accepting chemotaxis
E5093_RS11080	ENOG4108ZGA	chew protein
E5093_RS11085	ENOG4105M3Z	response regulator
E5093_RS11090	ENOG4108UNF	response regulator
E5093_RS11110	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E5093_RS11145	ENOG4105H1G	trap transporter solute receptor taxi family
E5093_RS11160	ENOG4105D1F	ATP-binding protein
E5093_RS11165	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E5093_RS11195	ENOG4105K6H	D-cysteine desulfhydrase
E5093_RS11210	ENOG4105CBX	hi0933 family
E5093_RS11245	ENOG4105DP0	ferredoxin-NADP reductase
E5093_RS11250	ENOG4105DUM	transcriptional regulator, lysR family
E5093_RS11260	ENOG4105VEQ	Cold shock protein
E5093_RS11275	ENOG4105C8S	subunit m
E5093_RS11280	ENOG4105D65	subunit l
E5093_RS11285	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5093_RS11290	ENOG4107UFS	subunit j
E5093_RS11295	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5093_RS11300	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E5093_RS11305	ENOG4108IEH	NADH dehydrogenase subunit g
E5093_RS11310	ENOG4107QIZ	NADH dehydrogenase
E5093_RS11315	ENOG4105GKE	subunit e
E5093_RS11330	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E5093_RS11340	ENOG4105CTB	Polyprenyl synthetase
E5093_RS11345	ENOG4105C7F	AcnD-accessory protein PrpF
E5093_RS11350	ENOG4105C85	amino acid
E5093_RS11370	ENOG4108RXX	maleylacetoacetate isomerase
E5093_RS11400	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
E5093_RS11410	ENOG4105D8T	Acyltransferase
E5093_RS11420	ENOG4105C03	ribonuclease
E5093_RS11425	ENOG4108Z03	MAF-like protein
E5093_RS11430	ENOG4105VQ7	Rod shape-determining protein MreD
E5093_RS11435	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E5093_RS11445	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E5093_RS11450	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E5093_RS11455	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E5093_RS11505	ENOG4105CND	Glycosyl transferase, family 2
E5093_RS11510	ENOG4107BJW	polysaccharide deacetylase
E5093_RS11540	ENOG4107R3N	Filamentation induced by cAMP protein fic
E5093_RS11560	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E5093_RS11585	ENOG41080HT	Transcriptional regulator, arsr family
E5093_RS11590	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E5093_RS11595	ENOG4107QX9	Thiol disulfide interChange protein
E5093_RS11600	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E5093_RS11610	ENOG4105DHQ	Histidine kinase
E5093_RS11620	ENOG4105DZR	Type I site-specific deoxyribonuclease
E5093_RS11695	ENOG4105DFP	Integrase
E5093_RS11705	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E5093_RS11710	ENOG4108VUY	thioesterase Superfamily protein
E5093_RS11715	ENOG4105D52	delta-aminolevulinic acid dehydratase
E5093_RS11720	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E5093_RS11730	ENOG4107RH8	nuclease SbcCD subunit D
E5093_RS11735	ENOG4105EYH	Exonuclease
E5093_RS11745	ENOG4105DFA	alanine racemase domain protein
E5093_RS11750	ENOG4105CZX	twitching motility protein
E5093_RS11755	ENOG4105CZX	twitching motility protein
E5093_RS11760	ENOG41090R7	Ferric uptake
E5093_RS11770	ENOG4105VDB	UPF0125 protein
E5093_RS11785	ENOG4105E7A	Glutamine amidotransferase
E5093_RS11800	ENOG4107QKV	phosphomannomutase
E5093_RS11810	ENOG4105C4R	Atp-dependent dna helicase
E5093_RS11815	ENOG4108ZG0	Ompa motb domain protein
E5093_RS11820	ENOG4106HNH	Acyl-transferase
E5093_RS11830	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E5093_RS11835	ENOG4107QMS	site-determining protein
E5093_RS11850	ENOG4105CNU	cell division protein FtsK
E5093_RS11855	ENOG4105C3M	thioredoxin reductase
E5093_RS11860	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E5093_RS11870	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E5093_RS11895	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E5093_RS11910	ENOG4108YXA	Membrane
E5093_RS11920	ENOG4105M4H	endoribonuclease L-psp
E5093_RS11935	ENOG4105EW9	transcriptional regulator AsnC family
E5093_RS11940	ENOG4107XGZ	Hydrolase
E5093_RS11945	ENOG4105DWF	phosphomethylpyrimidine kinase
E5093_RS11960	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E5093_RS11975	ENOG4105E3B	Multicopper oxidase
E5093_RS11985	ENOG4105DJV	ribulose-phosphate 3-epimerase
E5093_RS12000	ENOG4108M3P	Membrane
E5093_RS12020	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E5093_RS12025	ENOG41072GX	Peptidase M22 Glycoprotease
E5093_RS12030	ENOG4108Z0R	Transferase
E5093_RS12035	ENOG4105P8F	nudix hydrolase
E5093_RS12075	ENOG4105CRQ	synthase (Component I)
E5093_RS12085	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E5093_RS12090	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E5093_RS12150	ENOG4108KHX	Diguanylate cyclase
E5093_RS12155	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
E5093_RS12180	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E5093_RS12185	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E5093_RS12200	ENOG4105D3R	alkyl hydroperoxide reductase
E5093_RS12215	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E5093_RS12220	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E5093_RS12265	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E5093_RS12270	ENOG4108WBT	adenosyltransferase
E5093_RS12295	ENOG4105MSB	protein, conserved in bacteria
E5093_RS12305	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5093_RS12310	ENOG4105EB3	Histidine kinase
E5093_RS12320	ENOG4105CSU	acyl-Coa dehydrogenase
E5093_RS12325	ENOG4105CSU	acyl-Coa dehydrogenase
E5093_RS12330	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
E5093_RS12350	ENOG4105UGU	tonB-dependent Receptor
E5093_RS12365	ENOG4105C9M	aspartyl-trna synthetase
E5093_RS12380	ENOG4107J0A	lipopolysaccharide biosynthetic process
E5093_RS12395	ENOG4106WTF	Glycosyl transferase, family 2
E5093_RS12405	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5093_RS12410	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E5093_RS12415	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E5093_RS12420	ENOG4105BZU	Histidine kinase
E5093_RS12425	ENOG4105E9K	Isocitrate dehydrogenase
E5093_RS12430	ENOG4105DZR	Type I site-specific deoxyribonuclease
E5093_RS12440	ENOG4107XZC	Restriction modification system DNA (Specificity
E5093_RS12445	ENOG4105CVR	type I restriction-modification system
E5093_RS12460	ENOG4105KT5	UmuD protein
E5093_RS12465	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E5093_RS12470	ENOG4105K4U	addiction module toxin, RelE StbE family
E5093_RS12480	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E5093_RS12525	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E5093_RS12535	ENOG4108V0P	LemA family
E5093_RS12555	ENOG4105VIE	preprotein translocase, subunit YajC
E5093_RS12560	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5093_RS12565	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5093_RS12575	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5093_RS12590	ENOG4105C6T	cysteine synthase
E5093_RS12595	ENOG4105BZU	Histidine kinase
E5093_RS12600	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
E5093_RS12610	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E5093_RS12620	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5093_RS12625	ENOG4105W8H	transhydrogenase (subunit alpha
E5093_RS12630	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5093_RS12635	ENOG4106UX7	integral membrane protein
E5093_RS12680	ENOG4105DZR	Type I site-specific deoxyribonuclease
E5093_RS12690	ENOG4105EKX	Restriction modification system DNA (Specificity
E5093_RS12695	ENOG4105CB5	ATP-dependent DNA helicase recG
E5093_RS12700	ENOG4105CVR	type I restriction-modification system
E5093_RS12715	ENOG4105CFQ	glutamine synthetase
E5093_RS12730	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E5093_RS12735	ENOG4105C08	Histidine kinase
E5093_RS12745	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5093_RS12750	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5093_RS12830	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5093_RS12835	ENOG4105CUZ	uba thif-type nad fad binding protein
E5093_RS12840	ENOG4105F8V	Hydrolase, tatD family
E5093_RS12855	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E5093_RS12865	ENOG4105BZU	Histidine kinase
E5093_RS12870	ENOG4105CN1	protease
E5093_RS12900	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E5093_RS12905	ENOG4108DNC	Involved in acetate metabolism (By similarity)
E5093_RS12930	ENOG4107GFK	fumarate
E5093_RS12945	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E5093_RS12955	ENOG4105D05	Receptor
E5093_RS12960	ENOG4108IU3	tonb-dependent siderophore receptor
E5093_RS12965	ENOG4107E2E	PKHD-type hydroxylase
E5093_RS12975	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5093_RS12980	ENOG4105DWV	Homoserine O-trans-acetylase
E5093_RS12985	ENOG4105DWV	Homoserine O-trans-acetylase
E5093_RS13045	ENOG4105QNF	Outer membrane lipoprotein
E5093_RS13110	ENOG4105QNF	Outer membrane lipoprotein
E5093_RS13140	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E5093_RS13180	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E5093_RS13190	ENOG4105DGW	oligopeptidase A
E5093_RS13195	ENOG4105VKU	nucleicacid-binding protein
E5093_RS13205	ENOG4105EMK	carboxylate amino acid amine transporter
E5093_RS13240	ENOG4105C1G	acyl-Coa dehydrogenase
E5093_RS13245	ENOG4105CT3	Monooxygenase
E5093_RS13255	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5093_RS13260	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E5093_RS13280	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E5093_RS13295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E5093_RS13305	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E5093_RS13310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E5093_RS13345	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E5093_RS13375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E5093_RS13390	ENOG41089BK	Glutamine amido-transferase
E5093_RS13400	ENOG4105D7A	ATP-binding protein
E5093_RS13430	ENOG4105CK2	sodium dicarboxylate symporter
E5093_RS13435	ENOG4105C29	acyl-CoA thioesterase
E5093_RS13440	ENOG4105E55	glycerol-3-phosphate acyltransferase
E5093_RS13450	ENOG4105CB5	ATP-dependent DNA helicase recG
E5093_RS13455	ENOG4105MJ2	Competence protein
E5093_RS13465	ENOG4108URH	decarboxylase
E5093_RS13470	ENOG4107QUT	magnesium and cobalt transport protein CorA
E5093_RS13480	ENOG4105E3I	toluene tolerance
E5093_RS13485	ENOG4107PE3	Mammalian cell entry related domain protein
E5093_RS13490	ENOG4105CY3	ABC transporter, permease
E5093_RS13495	ENOG4105DHJ	ABC, transporter
E5093_RS13500	ENOG4105C1J	atp-dependent rna helicase
E5093_RS13505	ENOG4105ECY	inositol monophosphatase
E5093_RS13525	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E5093_RS13540	ENOG4105CSU	acyl-Coa dehydrogenase
E5093_RS13545	ENOG4105CSA	Coproporphyrinogen iii oxidase
E5093_RS13555	ENOG4107QI1	Mate efflux family protein
E5093_RS13565	ENOG4105NRA	50s ribosomal protein l31 type b
E5093_RS13570	ENOG4105WMR	Protein CrcB homolog
E5093_RS13590	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E5093_RS13605	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E5093_RS13610	ENOG4105IPI	Membrane
E5093_RS13615	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5093_RS13620	ENOG4105VCH	membrane
E5093_RS13625	ENOG4107QF7	multi-drug
E5093_RS13635	ENOG4105CQB	FAD linked oxidase domain protein
E5093_RS13640	ENOG4108JQ1	Dehydrogenase
E5093_RS13665	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E5093_RS13670	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
E5093_RS13675	ENOG4107IFA	Lipase (EC 3.1.1.3)
E5093_RS13680	ENOG4107IFA	Lipase (EC 3.1.1.3)
E5093_RS13690	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E5093_RS13700	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E5093_RS13705	ENOG4105K5M	30s ribosomal protein S16
E5093_RS13750	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E5093_RS13755	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E5093_RS13760	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5093_RS13765	ENOG4105KME	endoribonuclease L-psp
E5093_RS13775	ENOG4108UQY	Iron-storage protein
E5093_RS13780	ENOG4108YSG	O-Antigen polymerase
E5093_RS13785	ENOG4105YWY	
E5093_RS13795	ENOG4105KHS	type IV fimbrial pilin protein
E5093_RS13805	ENOG4105HA9	of methanol dehydrogenase type
E5093_RS13810	ENOG4108V0P	LemA family
E5093_RS13820	ENOG4105BZ8	glutamate synthase
E5093_RS13825	ENOG4105CBC	glutamate synthase
E5093_RS13845	ENOG4105E4G	Type IV pilus
E5093_RS13870	ENOG4108JQC	penicillin-binding protein 1A
E5093_RS13885	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E5093_RS13890	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E5093_RS13895	ENOG4105CJN	penicillin-binding protein
E5093_RS13905	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E5093_RS13910	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E5093_RS13920	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E5093_RS13940	ENOG4105C5H	ABC transporter
E5093_RS13950	ENOG4105PDP	Short chain dehydrogenase
E5093_RS13980	ENOG4105E0F	Histidine kinase
E5093_RS13985	ENOG4105CYC	Transferase
E5093_RS14015	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E5093_RS14035	ENOG4108Q5Y	Membrane
E5093_RS14050	ENOG4105CUV	Homoserine Kinase
E5093_RS14090	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E5093_RS14115	ENOG4105CVN	desaturase
E5093_RS14120	ENOG4105EUB	pirin domain protein
E5093_RS14125	ENOG4105D3R	alkyl hydroperoxide reductase
E5093_RS14160	ENOG4105E3B	Multicopper oxidase
E5093_RS14215	ENOG4105E3B	Multicopper oxidase
E5093_RS14230	ENOG4105GR3	Histidine kinase
E5093_RS14235	ENOG4107PU6	Membrane
E5093_RS14240	ENOG4105C59	p-type ATPase
E5093_RS14280	ENOG4108BUD	transposase
E5093_RS14330	ENOG4108BUD	transposase
E5093_RS14340	ENOG4108UUM	single-stranded DNA-binding protein
E5093_RS14345	ENOG4107RDB	Major Facilitator
E5093_RS14355	ENOG4105ETU	transcriptional activator (TenA
E5093_RS14360	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E5093_RS14365	ENOG4105BZU	Histidine kinase
E5093_RS14375	ENOG4105C94	Transporter
E5093_RS14395	ENOG4107QN1	sodium solute
E5093_RS14400	ENOG41062QD	Membrane
E5093_RS14405	ENOG4105BZU	Histidine kinase
E5093_RS14420	ENOG4108UZX	fmn reductase
E5093_RS14430	ENOG4107T8P	acyl-Coa dehydrogenase
E5093_RS14435	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5093_RS14440	ENOG4105D64	Mechanosensitive ion channel
E5093_RS14450	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E5093_RS14455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5093_RS14460	ENOG4105NPE	arsR family transcriptional regulator
E5093_RS14465	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
E5093_RS14480	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E5093_RS14495	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5093_RS14515	ENOG4107QSN	dihydrolipoamide acetyltransferase
E5093_RS14520	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E5093_RS14540	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E5093_RS14545	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E5093_RS14550	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E5093_RS14560	ENOG4105DFU	Cell wall formation (By similarity)
E5093_RS14565	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E5093_RS14570	ENOG4105D7Z	glutathione synthase
E5093_RS14575	ENOG4108V06	Glutathione peroxidase
E5093_RS14580	ENOG4105K56	Transcriptional regulator
E5093_RS14595	ENOG4105CGK	Exodeoxyribonuclease III
E5093_RS14600	ENOG4105KUZ	arsenate reductase
E5093_RS14615	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E5093_RS14620	ENOG4105BZU	Histidine kinase
E5093_RS14625	ENOG4108K3A	Glutathione S-transferase
E5093_RS14665	ENOG4108Z7F	N-acetyltransferase
E5093_RS14670	ENOG41061H0	Monooxygenase
E5093_RS14680	ENOG4108Z2U	ureidoglycolate hydrolase
E5093_RS14690	ENOG4105C8P	)-transporter
E5093_RS14700	ENOG4108IV0	ABC, transporter
E5093_RS14705	ENOG4105C0Z	ABC transporter
E5093_RS14715	ENOG4105C32	Amino acid ABC transporter (Permease)
E5093_RS14720	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
E5093_RS14725	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5093_RS14730	ENOG4105IPS	esterase
E5093_RS14740	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E5093_RS14745	ENOG4105D9M	gamma-glutamylcysteine synthetase
E5093_RS14760	ENOG4106BRA	Membrane
E5093_RS14765	ENOG4105CHM	Aminotransferase
E5093_RS14770	ENOG4107QJQ	Mate efflux family protein
E5093_RS14785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5093_RS14790	ENOG4105BZU	Histidine kinase
E5093_RS14800	ENOG4105KHC	sulfurtransferase
E5093_RS14815	ENOG4105CH6	catalase
E5093_RS14835	ENOG4105EAC	phosphoserine phosphatase
E5093_RS14850	ENOG4105C09	Bile acid
E5093_RS14855	ENOG4108RWI	nicotinamidase
E5093_RS14860	ENOG4108SC4	)-transporter
E5093_RS14865	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5093_RS14875	ENOG4105C8V	SAICAR synthetase
E5093_RS14880	ENOG4105D1H	recombination factor protein RarA
E5093_RS14885	ENOG4108ZZ3	UPF0260 protein
E5093_RS14905	ENOG4105CEN	a g-specific adenine glycosylase
E5093_RS14910	ENOG4105FAA	peptidase M23
E5093_RS14920	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E5093_RS14925	ENOG4105DQ4	alcohol dehydrogenase
E5093_RS14930	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5093_RS14935	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5093_RS14940	ENOG4105CJR	Integral membrane protein (MviN
E5093_RS14945	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E5093_RS14950	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E5093_RS14955	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E5093_RS14960	ENOG4105EJ2	Transcriptional regulator
E5093_RS14965	ENOG4108Z33	Thiol disulfide Interchange Protein
E5093_RS14970	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E5093_RS14975	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5093_RS14980	ENOG4105UBK	short-chain dehydrogenase reductase
E5093_RS15005	ENOG4107QZM	n-acetylglutamate synthase
E5093_RS15010	ENOG4105GVF	(ABC) transporter
E5093_RS15015	ENOG4105GVF	(ABC) transporter
E5093_RS15020	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
E5093_RS15025	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E5093_RS15030	ENOG4108VM9	ABC, transporter
E5093_RS15035	ENOG4108R86	Transcriptional regulator
E5093_RS15045	ENOG4105DTN	riboflavin biosynthesis protein ribF
E5093_RS15050	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E5093_RS15055	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E5093_RS15060	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E5093_RS15075	ENOG4105D2S	major facilitator superfamily
E5093_RS15105	ENOG4105CGH	5'-nucleotidase
E5093_RS15115	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5093_RS15120	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E5093_RS15130	ENOG4108821	RND type efflux pump
E5093_RS15135	ENOG4108821	RND type efflux pump
E5093_RS15140	ENOG4108821	RND type efflux pump
E5093_RS15145	ENOG4105C5H	ABC transporter
E5093_RS15150	ENOG4105E2A	Dehydrogenase
E5093_RS15155	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5093_RS15165	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)