locus-tag	class	description
F9230_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F9230_RS00010	COG0592	DNA-directed DNA polymerase activity
F9230_RS00020	COG0187	DNA topoisomerase II activity
F9230_RS00030	COG0488	(ABC) transporter
F9230_RS00090	COG0657	acetylesterase activity
F9230_RS00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9230_RS00130	COG2814	Major facilitator Superfamily
F9230_RS00140	COG0733	neurotransmitter:sodium symporter activity
F9230_RS00185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9230_RS00185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F9230_RS00200	COG0129	dihydroxy-acid dehydratase activity
F9230_RS00210	COG4774	siderophore transport
F9230_RS00220	COG0583	DNA-binding transcription factor activity
F9230_RS00225	COG2233	PERMEase
F9230_RS00235	COG1309	transcriptional regulator
F9230_RS00255	COG0484	heat shock protein binding
F9230_RS00265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F9230_RS00280	COG0436	Aminotransferase
F9230_RS00285	COG1064	alcohol dehydrogenase
F9230_RS00290	COG2818	Glycosylase
F9230_RS00320	COG5487	UPF0391 membrane protein
F9230_RS00325	COG2983	Belongs to the UPF0260 family
F9230_RS00330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9230_RS00350	COG4160	amino acid transport
F9230_RS00355	COG4215	(ABC) transporter
F9230_RS00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9230_RS00385	COG1335	isochorismatase
F9230_RS00390	COG0385	Bile acid
F9230_RS00460	COG0534	Mate efflux family protein
F9230_RS00465	COG0436	Aminotransferase
F9230_RS00470	COG2733	membrane
F9230_RS00485	COG2918	glutathione biosynthetic process
F9230_RS00490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F9230_RS00500	COG3150	esterase
F9230_RS00585	COG3706	GGDEF domain
F9230_RS00590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F9230_RS00605	COG1393	Belongs to the ArsC family
F9230_RS00610	COG0708	Exodeoxyribonuclease III
F9230_RS00620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9230_RS00635	COG1846	Transcriptional regulator
F9230_RS00640	COG0386	Belongs to the glutathione peroxidase family
F9230_RS00645	COG0189	ligase activity
F9230_RS00655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9230_RS00665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F9230_RS00675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F9230_RS00705	COG2119	membrane
F9230_RS00710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_RS00710	COG0426	domain, Protein
F9230_RS00735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F9230_RS00760	COG1902	pentaerythritol trinitrate reductase activity
F9230_RS00765	COG1519	Transferase
F9230_RS00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9230_RS00775	COG0668	transmembrane transport
F9230_RS00780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9230_RS00790	COG0579	oxidoreductase
F9230_RS00800	COG0307	riboflavin synthase, alpha
F9230_RS00820	COG0431	NADPH-dependent FMN reductase
F9230_RS00835	COG2205	protein histidine kinase activity
F9230_RS00835	COG0784	Response regulator, receiver
F9230_RS00840	COG3162	membrane
F9230_RS00845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9230_RS00855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9230_RS00865	COG3706	GGDEF domain
F9230_RS00885	COG0351	phosphomethylpyrimidine kinase
F9230_RS00885	COG0352	thiamine-phosphate diphosphorylase activity
F9230_RS00885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9230_RS00895	COG2814	Major facilitator Superfamily
F9230_RS00900	COG0629	single-stranded DNA binding
F9230_RS00910	COG0583	DNA-binding transcription factor activity
F9230_RS00915	COG1301	dicarboxylic acid transport
F9230_RS00930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_RS00945	COG1335	isochorismatase
F9230_RS00955	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
F9230_RS01015	COG0582	viral genome integration into host DNA
F9230_RS01045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F9230_RS01070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F9230_RS01075	COG1278	Cold shock
F9230_RS01090	COG0531	amino acid
F9230_RS01095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9230_RS01130	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F9230_RS01165	COG0427	acetyl-CoA hydrolase
F9230_RS01195	COG4221	oxidoreductase activity
F9230_RS01200	COG2873	o-acetylhomoserine
F9230_RS01205	COG0488	(ABC) transporter
F9230_RS01225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9230_RS01240	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9230_RS01260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9230_RS01265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F9230_RS01275	COG2226	methyltransferase
F9230_RS01325	COG0070	glutamate synthase
F9230_RS01325	COG0069	glutamate synthase activity
F9230_RS01325	COG0067	glutamate synthase
F9230_RS01330	COG0493	'glutamate synthase
F9230_RS01340	COG1704	LemA family
F9230_RS01345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F9230_RS01390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9230_RS01395	COG1758	RNA polymerase activity
F9230_RS01400	COG0194	GDP metabolic process
F9230_RS01410	COG4969	Belongs to the N-Me-Phe pilin family
F9230_RS01445	COG0228	four-way junction DNA binding
F9230_RS01450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F9230_RS01460	COG0335	large ribosomal subunit rRNA binding
F9230_RS01475	COG5380	lipid catabolic process
F9230_RS01480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F9230_RS01500	COG5006	permease, DMT superfamily
F9230_RS01505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9230_RS01510	COG0277	FAD linked oxidase domain protein
F9230_RS01520	COG2197	response regulator
F9230_RS01525	COG0477	Major facilitator Superfamily
F9230_RS01535	COG2814	Major facilitator Superfamily
F9230_RS01540	COG1289	transmembrane transporter activity
F9230_RS01545	COG2032	superoxide dismutase activity
F9230_RS01550	COG0628	permease
F9230_RS01555	COG1192	Involved in chromosome partitioning
F9230_RS01565	COG2226	methyltransferase
F9230_RS01580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F9230_RS01585	COG0254	rRNA binding
F9230_RS01590	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9230_RS01600	COG0534	Mate efflux family protein
F9230_RS01610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9230_RS01630	COG1960	acyl-CoA dehydrogenase activity
F9230_RS01650	COG0408	coproporphyrinogen oxidase activity
F9230_RS01655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9230_RS01675	COG0513	Belongs to the DEAD box helicase family
F9230_RS01680	COG1127	ABC transporter
F9230_RS01685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9230_RS01690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F9230_RS01695	COG2854	intermembrane phospholipid transfer
F9230_RS01705	COG0598	Magnesium transport protein CorA
F9230_RS01715	COG0494	nUDIX hydrolase
F9230_RS01720	COG1040	competence protein
F9230_RS01725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F9230_RS01750	COG2937	Belongs to the GPAT DAPAT family
F9230_RS01755	COG1946	Acyl-CoA thioesterase
F9230_RS01760	COG1301	dicarboxylic acid transport
F9230_RS01775	COG1959	2 iron, 2 sulfur cluster binding
F9230_RS01785	COG0433	COG0433 Predicted ATPase
F9230_RS01805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F9230_RS01810	COG0088	Forms part of the polypeptide exit tunnel
F9230_RS01825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F9230_RS01875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F9230_RS01880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F9230_RS01890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F9230_RS01915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F9230_RS01930	COG0202	RNA polymerase activity
F9230_RS01935	COG0203	ribosomal protein L17
F9230_RS01940	COG2072	flavoprotein involved in K transport
F9230_RS01950	COG1960	acyl-CoA dehydrogenase activity
F9230_RS01955	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F9230_RS01985	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F9230_RS01990	COG0339	signal peptide processing
F9230_RS01995	COG2720	vancomycin resistance protein
F9230_RS02000	COG0557	exoribonuclease II activity
F9230_RS02030	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9230_RS02045	COG1295	ribonuclease BN
F9230_RS02085	COG4773	Receptor
F9230_RS02095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F9230_RS02100	COG1702	phosphate starvation-inducible protein PhoH
F9230_RS02105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9230_RS02110	COG0739	heme binding
F9230_RS02110	COG0741	lytic transglycosylase activity
F9230_RS02110	COG1196	nuclear chromosome segregation
F9230_RS02120	COG0039	L-malate dehydrogenase activity
F9230_RS02145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F9230_RS02150	COG1183	phosphatidylcholine synthase activity
F9230_RS02210	COG1607	acyl-coa hydrolase
F9230_RS02225	COG1666	GTP binding
F9230_RS02245	COG2350	Protein conserved in bacteria
F9230_RS02255	COG0613	PHP domain protein
F9230_RS02260	COG3781	membrane
F9230_RS02270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F9230_RS02295	COG1162	GTPase activity
F9230_RS02300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F9230_RS02325	COG1538	Outer membrane efflux protein
F9230_RS02330	COG1136	(ABC) transporter
F9230_RS02330	COG0577	efflux transmembrane transporter activity
F9230_RS02335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_RS02360	COG0028	Belongs to the TPP enzyme family
F9230_RS02365	COG0440	acetolactate synthase activity
F9230_RS02425	COG1426	Protein conserved in bacteria
F9230_RS02445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9230_RS02470	COG1862	Preprotein translocase
F9230_RS02480	COG1704	LemA family
F9230_RS02490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F9230_RS02500	COG5002	protein histidine kinase activity
F9230_RS02505	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F9230_RS02535	COG0438	transferase activity, transferring glycosyl groups
F9230_RS02555	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F9230_RS02570	COG0463	Glycosyl transferase, family 2
F9230_RS02600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F9230_RS02630	COG3223	Belongs to the PsiE family
F9230_RS02635	COG1960	acyl-CoA dehydrogenase activity
F9230_RS02640	COG1960	acyl-CoA dehydrogenase activity
F9230_RS02650	COG2205	protein histidine kinase activity
F9230_RS02655	COG0745	RESPONSE REGULATOR receiver
F9230_RS02660	COG1113	amino acid transport
F9230_RS02670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F9230_RS02690	COG2096	Adenosyltransferase
F9230_RS02695	COG4206	TonB-dependent receptor
F9230_RS02720	COG3083	sulfuric ester hydrolase activity
F9230_RS02750	COG0285	dihydrofolate synthase activity
F9230_RS02770	COG0450	alkyl hydroperoxide reductase
F9230_RS02790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F9230_RS02795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F9230_RS02825	COG2199	diguanylate cyclase activity
F9230_RS02860	COG2814	Major facilitator Superfamily
F9230_RS02875	COG0693	protein deglycase activity
F9230_RS02900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F9230_RS02910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9230_RS02960	COG0494	nUDIX hydrolase
F9230_RS02965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9230_RS02970	COG1214	PFAM Peptidase M22, glycoprotease
F9230_RS02975	COG1968	undecaprenyl-diphosphatase activity
F9230_RS03010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F9230_RS03020	COG2132	Multicopper oxidase
F9230_RS03045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9230_RS03055	COG0351	phosphomethylpyrimidine kinase
F9230_RS03055	COG0352	thiamine-phosphate diphosphorylase activity
F9230_RS03055	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9230_RS03085	COG0251	oxidation-reduction process
F9230_RS03090	COG1113	amino acid transport
F9230_RS03100	COG1981	membrane
F9230_RS03115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F9230_RS03160	COG0456	acetyltransferase
F9230_RS03170	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F9230_RS03175	COG0492	ferredoxin-NADP+ reductase activity
F9230_RS03180	COG0531	amino acid
F9230_RS03180	COG1674	ftsk spoiiie
F9230_RS03195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F9230_RS03200	COG2894	cell division
F9230_RS03205	COG0850	regulation of cytokinetic process
F9230_RS03215	COG0204	Acyl-transferase
F9230_RS03220	COG2885	chlorophyll binding
F9230_RS03225	COG0210	DNA helicase
F9230_RS03230	COG0756	dUTP diphosphatase activity
F9230_RS03245	COG0121	glutamine amidotransferase
F9230_RS03260	COG2914	Belongs to the UPF0125 (RnfH) family
F9230_RS03265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9230_RS03270	COG0735	belongs to the Fur family
F9230_RS03300	COG0420	3'-5' exonuclease activity
F9230_RS03305	COG5001	Diguanylate cyclase
F9230_RS03305	COG4251	negative regulation of phosphorylation
F9230_RS03305	COG3706	GGDEF domain
F9230_RS03305	COG2203	Gaf domain
F9230_RS03315	COG1090	epimerase
F9230_RS03330	COG2050	protein possibly involved in aromatic compounds catabolism
F9230_RS03335	COG1566	PFAM secretion protein HlyD family protein
F9230_RS03340	COG2814	Major facilitator Superfamily
F9230_RS03345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F9230_RS03580	COG4695	Portal protein
F9230_RS03585	COG0582	viral genome integration into host DNA
F9230_RS03645	COG1215	transferase activity, transferring glycosyl groups
F9230_RS03660	COG1968	undecaprenyl-diphosphatase activity
F9230_RS03665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F9230_RS03670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F9230_RS03675	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F9230_RS03680	COG2205	protein histidine kinase activity
F9230_RS03685	COG0745	RESPONSE REGULATOR receiver
F9230_RS03690	COG0697	spore germination
F9230_RS03695	COG2721	sulfolactate sulfo-lyase activity
F9230_RS03700	COG2271	Major facilitator Superfamily
F9230_RS03710	COG1012	belongs to the aldehyde dehydrogenase family
F9230_RS03720	COG2186	Transcriptional regulator
F9230_RS03730	COG1802	Transcriptional regulator
F9230_RS03785	COG2814	Major facilitator Superfamily
F9230_RS03790	COG0583	DNA-binding transcription factor activity
F9230_RS03800	COG1522	sequence-specific DNA binding
F9230_RS03810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_RS03830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_RS03840	COG1294	oxidase, subunit
F9230_RS03845	COG1271	oxidase subunit
F9230_RS03860	COG1113	amino acid transport
F9230_RS03870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9230_RS03875	COG1012	belongs to the aldehyde dehydrogenase family
F9230_RS03885	COG1522	sequence-specific DNA binding
F9230_RS03890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9230_RS03900	COG3138	arginine N-succinyltransferase
F9230_RS03905	COG1012	belongs to the aldehyde dehydrogenase family
F9230_RS03910	COG3724	N-succinylarginine dihydrolase activity
F9230_RS03920	COG1113	amino acid transport
F9230_RS03945	COG1414	Transcriptional regulator
F9230_RS03950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9230_RS03955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_RS03960	COG0183	Belongs to the thiolase family
F9230_RS03965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9230_RS03970	COG0596	Alpha beta hydrolase
F9230_RS03975	COG2271	Major facilitator Superfamily
F9230_RS03980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9230_RS03985	COG3485	protocatechuate 3,4-dioxygenase
F9230_RS03990	COG3485	protocatechuate 3,4-dioxygenase
F9230_RS03995	COG0710	3-dehydroquinate dehydratase activity
F9230_RS04000	COG3420	alginic acid biosynthetic process
F9230_RS04005	COG3659	wide pore channel activity
F9230_RS04010	COG4993	Dehydrogenase
F9230_RS04015	COG4772	TonB-dependent receptor
F9230_RS04025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_RS04035	COG0583	DNA-binding transcription factor activity
F9230_RS04040	COG2610	gluconate transmembrane transporter activity
F9230_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS04055	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F9230_RS04090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9230_RS04100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9230_RS04105	COG1077	Cell shape determining protein MreB Mrl
F9230_RS04110	COG1792	Involved in formation and maintenance of cell shape
F9230_RS04115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F9230_RS04120	COG0424	maF-like protein
F9230_RS04135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9230_RS04185	COG0640	Transcriptional regulator
F9230_RS04195	COG0798	PFAM Bile acid sodium symporter
F9230_RS04200	COG0431	NADPH-dependent FMN reductase
F9230_RS04205	COG2072	flavoprotein involved in K transport
F9230_RS04215	COG0625	glutathione transferase activity
F9230_RS04235	COG1113	amino acid transport
F9230_RS04245	COG0583	DNA-binding transcription factor activity
F9230_RS04250	COG0006	proline dipeptidase activity
F9230_RS04265	COG1012	belongs to the aldehyde dehydrogenase family
F9230_RS04275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_RS04280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9230_RS04280	COG0723	plastoquinol--plastocyanin reductase activity
F9230_RS04305	COG0697	spore germination
F9230_RS04320	COG0582	viral genome integration into host DNA
F9230_RS04330	COG1113	amino acid transport
F9230_RS04335	COG2828	Protein conserved in bacteria
F9230_RS04340	COG0142	geranyltranstransferase activity
F9230_RS04355	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9230_RS04380	COG0745	RESPONSE REGULATOR receiver
F9230_RS04385	COG0642	Histidine kinase
F9230_RS04400	COG0004	ammonium transporteR
F9230_RS04410	COG1126	abc transporter atp-binding protein
F9230_RS04415	COG0765	amino acid transport
F9230_RS04420	COG0765	amino acid transport
F9230_RS04440	COG0668	transmembrane transport
F9230_RS04455	COG2081	HI0933 family
F9230_RS04460	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F9230_RS04490	COG4716	Myosin-crossreactive antigen
F9230_RS04525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9230_RS04525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9230_RS04550	COG0489	protein tyrosine kinase activity
F9230_RS04565	COG2358	TRAP transporter, solute receptor (TAXI family
F9230_RS04635	COG0840	transmembrane signaling receptor activity
F9230_RS04640	COG0643	Histidine kinase
F9230_RS04640	COG0784	Response regulator, receiver
F9230_RS04640	COG2198	Histidine kinase
F9230_RS04650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F9230_RS04665	COG2832	Protein of unknown function (DUF454)
F9230_RS04735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F9230_RS04745	COG1289	transmembrane transporter activity
F9230_RS04750	COG2814	Major facilitator Superfamily
F9230_RS04765	COG0786	glutamate:sodium symporter activity
F9230_RS04770	COG1115	amino acid carrier protein
F9230_RS04780	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9230_RS04785	COG1607	acyl-coa hydrolase
F9230_RS04795	COG0523	cobalamin synthesis protein
F9230_RS04800	COG4681	YaeQ
F9230_RS04810	COG2199	diguanylate cyclase activity
F9230_RS04810	COG2203	Gaf domain
F9230_RS04855	COG0477	Major facilitator Superfamily
F9230_RS04860	COG0242	peptide deformylase activity
F9230_RS04865	COG2207	Transcriptional regulator
F9230_RS04870	COG2223	nitrite transmembrane transporter activity
F9230_RS04900	COG0306	phosphate transporter
F9230_RS04925	COG4771	TonB-dependent receptor
F9230_RS04950	COG4181	ATPase activity
F9230_RS04955	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F9230_RS04975	COG0583	DNA-binding transcription factor activity
F9230_RS04985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_RS04990	COG1773	rubredoxin
F9230_RS04995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F9230_RS05035	COG1695	Transcriptional regulator
F9230_RS05050	COG0604	alcohol dehydrogenase
F9230_RS05050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9230_RS05050	COG3321	synthase
F9230_RS05050	COG4221	oxidoreductase activity
F9230_RS05090	COG0477	Major facilitator Superfamily
F9230_RS05110	COG1597	lipid kinase activity
F9230_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS05200	COG1063	alcohol dehydrogenase
F9230_RS05245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F9230_RS05250	COG1335	isochorismatase
F9230_RS05270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F9230_RS05290	COG2323	membrane
F9230_RS05335	COG2223	nitrite transmembrane transporter activity
F9230_RS05340	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F9230_RS05345	COG1877	trehalose-phosphatase activity
F9230_RS05360	COG1570	exodeoxyribonuclease VII activity
F9230_RS05405	COG0582	viral genome integration into host DNA
F9230_RS05415	COG0641	radical SAM
F9230_RS05420	COG3119	arylsulfatase activity
F9230_RS05445	COG0742	ribosomal rna small subunit methyltransferase
F9230_RS05450	COG0768	penicillin binding
F9230_RS05475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F9230_RS05480	COG2878	Part of a membrane complex involved in electron transport
F9230_RS05485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9230_RS05495	COG3384	dioxygenase
F9230_RS05505	COG2234	aminopeptidase activity
F9230_RS05520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F9230_RS05530	COG2217	Heavy metal translocating P-type atpase
F9230_RS05535	COG0583	DNA-binding transcription factor activity
F9230_RS05560	COG4770	biotin carboxylase activity
F9230_RS05565	COG3284	Transcriptional regulator
F9230_RS05590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9230_RS05595	COG0235	Class ii aldolase
F9230_RS05600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_RS05625	COG0006	proline dipeptidase activity
F9230_RS05650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9230_RS05655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9230_RS05675	COG2915	High frequency lysogenization protein hflD homolog
F9230_RS05695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9230_RS05700	COG1686	Belongs to the peptidase S11 family
F9230_RS05720	COG0789	Transcriptional regulator
F9230_RS05735	COG0753	catalase activity
F9230_RS05755	COG0583	DNA-binding transcription factor activity
F9230_RS05775	COG0657	acetylesterase activity
F9230_RS05790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9230_RS05795	COG1388	LysM domain
F9230_RS05795	COG0741	lytic transglycosylase activity
F9230_RS05800	COG4166	transmembrane transport
F9230_RS05805	COG4174	ABC transporter (Permease)
F9230_RS05810	COG4239	(ABC) transporter, permease
F9230_RS05815	COG4172	Belongs to the ABC transporter superfamily
F9230_RS05830	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F9230_RS05855	COG0833	amino acid
F9230_RS05865	COG0833	amino acid
F9230_RS05875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9230_RS05880	COG0418	dihydroorotase activity
F9230_RS05885	COG5001	Diguanylate cyclase
F9230_RS05885	COG4251	negative regulation of phosphorylation
F9230_RS05885	COG3706	GGDEF domain
F9230_RS05885	COG2203	Gaf domain
F9230_RS05900	COG2186	Transcriptional regulator
F9230_RS05910	COG0277	FAD linked oxidase domain protein
F9230_RS05915	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9230_RS05915	COG1902	pentaerythritol trinitrate reductase activity
F9230_RS05925	COG0583	DNA-binding transcription factor activity
F9230_RS05945	COG1012	belongs to the aldehyde dehydrogenase family
F9230_RS05950	COG0531	amino acid
F9230_RS05955	COG2957	Belongs to the agmatine deiminase family
F9230_RS05980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9230_RS05985	COG1960	acyl-CoA dehydrogenase activity
F9230_RS05990	COG1024	Enoyl-CoA hydratase
F9230_RS06040	COG1773	rubredoxin
F9230_RS06045	COG3119	arylsulfatase activity
F9230_RS06060	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F9230_RS06070	COG0280	phosphate acetyltransferase
F9230_RS06070	COG0281	malic enzyme
F9230_RS06075	COG5001	Diguanylate cyclase
F9230_RS06075	COG1716	ATPase activity
F9230_RS06080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9230_RS06085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F9230_RS06090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F9230_RS06130	COG1960	acyl-CoA dehydrogenase activity
F9230_RS06135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9230_RS06140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9230_RS06155	COG1671	Belongs to the UPF0178 family
F9230_RS06170	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9230_RS06175	COG1136	(ABC) transporter
F9230_RS06180	COG2333	competence protein COMEC
F9230_RS06180	COG0658	competence protein
F9230_RS06200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9230_RS06205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F9230_RS06210	COG0628	permease
F9230_RS06215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F9230_RS06245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9230_RS06265	COG0823	Involved in the tonB-independent uptake of proteins
F9230_RS06285	COG0824	Thioesterase
F9230_RS06300	COG2255	four-way junction helicase activity
F9230_RS06305	COG0632	four-way junction helicase activity
F9230_RS06315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F9230_RS06315	COG0047	phosphoribosylformylglycinamidine synthase activity
F9230_RS06330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9230_RS06330	COG3323	Protein of unknown function (DUF1653)
F9230_RS06335	COG0778	Nitroreductase
F9230_RS06340	COG1024	Enoyl-CoA hydratase
F9230_RS06345	COG1051	belongs to the nudix hydrolase family
F9230_RS06345	COG1056	cytidyltransferase-related domain
F9230_RS06350	COG2353	YceI-like domain
F9230_RS06355	COG0583	DNA-binding transcription factor activity
F9230_RS06365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9230_RS06380	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F9230_RS06385	COG0602	queuosine metabolic process
F9230_RS06405	COG0583	DNA-binding transcription factor activity
F9230_RS06410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F9230_RS06415	COG4208	sulfate ABC transporter
F9230_RS06430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9230_RS06440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9230_RS06460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9230_RS06475	COG0681	Belongs to the peptidase S26 family
F9230_RS06485	COG0571	ribonuclease III activity
F9230_RS06490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F9230_RS06500	COG1381	Involved in DNA repair and RecF pathway recombination
F9230_RS06505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F9230_RS06540	COG0436	Aminotransferase
F9230_RS06550	COG2199	diguanylate cyclase activity
F9230_RS06565	COG0556	nucleotide-excision repair
F9230_RS06595	COG0702	epimerase
F9230_RS06600	COG1733	regulation of RNA biosynthetic process
F9230_RS06610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F9230_RS06615	COG0671	phosphoesterase, PA-phosphatase related
F9230_RS06620	COG4772	TonB-dependent receptor
F9230_RS06630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9230_RS06635	COG0076	glutamate decarboxylase activity
F9230_RS06645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F9230_RS06650	COG0573	inorganic phosphate transmembrane transporter activity
F9230_RS06660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9230_RS06665	COG0616	signal peptide processing
F9230_RS06670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9230_RS06675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F9230_RS06680	COG1067	ATP-dependent peptidase activity
F9230_RS06700	COG0254	rRNA binding
F9230_RS06720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F9230_RS06725	COG1966	Carbon starvation protein
F9230_RS06730	COG2879	small protein
F9230_RS06735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F9230_RS06740	COG0714	Associated with various cellular activities
F9230_RS06845	COG3220	belongs to the UPF0276 family
F9230_RS06855	COG1595	DNA-templated transcription, initiation
F9230_RS06875	COG2199	diguanylate cyclase activity
F9230_RS06875	COG2203	Gaf domain
F9230_RS06895	COG2351	hydroxyisourate hydrolase activity
F9230_RS06910	COG3046	protein related to deoxyribodipyrimidine photolyase
F9230_RS06915	COG2816	NAD+ diphosphatase activity
F9230_RS06940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9230_RS06955	COG0642	Histidine kinase
F9230_RS06990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9230_RS06995	COG0783	Belongs to the Dps family
F9230_RS07130	COG3539	Fimbrial protein
F9230_RS07160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F9230_RS07210	COG0625	glutathione transferase activity
F9230_RS07220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_RS07225	COG1473	amidohydrolase
F9230_RS07230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_RS07235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9230_RS07245	COG0765	amino acid transport
F9230_RS07250	COG1126	abc transporter atp-binding protein
F9230_RS07270	COG0457	Tetratricopeptide repeat
F9230_RS07270	COG0463	Glycosyl transferase, family 2
F9230_RS07275	COG1538	Outer membrane efflux protein
F9230_RS07290	COG0697	spore germination
F9230_RS07295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_RS07315	COG3712	iron ion homeostasis
F9230_RS07325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_RS07330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9230_RS07335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9230_RS07375	COG1131	(ABC) transporter
F9230_RS07380	COG0842	Transport permease protein
F9230_RS07385	COG0842	Transport permease protein
F9230_RS07410	COG1309	transcriptional regulator
F9230_RS07475	COG1733	regulation of RNA biosynthetic process
F9230_RS07480	COG0604	alcohol dehydrogenase
F9230_RS07490	COG1278	Cold shock
F9230_RS07500	COG3038	cytochrome b561
F9230_RS07520	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9230_RS07530	COG5377	YqaJ viral recombinase family
F9230_RS07755	COG3772	lysozyme
F9230_RS07805	COG2070	2-Nitropropane dioxygenase
F9230_RS07830	COG3634	alkyl hydroperoxide reductase activity
F9230_RS07850	COG0436	Aminotransferase
F9230_RS07855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9230_RS07860	COG0386	Belongs to the glutathione peroxidase family
F9230_RS07885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F9230_RS07900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9230_RS07925	COG0012	GTP binding
F9230_RS07930	COG2011	ABC-type metal ion transport system permease component
F9230_RS07935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9230_RS07940	COG1464	Belongs to the NlpA lipoprotein family
F9230_RS07945	COG1464	Belongs to the NlpA lipoprotein family
F9230_RS07975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F9230_RS07985	COG0204	Acyl-transferase
F9230_RS08025	COG0424	maF-like protein
F9230_RS08035	COG0126	phosphoglycerate kinase activity
F9230_RS08050	COG0697	spore germination
F9230_RS08080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9230_RS08085	COG3781	membrane
F9230_RS08115	COG0506	proline dehydrogenase activity
F9230_RS08115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9230_RS08115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9230_RS08125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9230_RS08130	COG1027	Aspartate ammonia-lyase
F9230_RS08140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9230_RS08170	COG0316	Belongs to the HesB IscA family
F9230_RS08175	COG0822	iron-sulfur transferase activity
F9230_RS08185	COG1959	2 iron, 2 sulfur cluster binding
F9230_RS08200	COG0776	regulation of translation
F9230_RS08205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9230_RS08230	COG0537	adenosine 5'-monophosphoramidase activity
F9230_RS08290	COG2175	clavaminate synthase activity
F9230_RS08295	COG3246	L-lysine catabolic process to acetate
F9230_RS08315	COG2855	membrane
F9230_RS08345	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS08355	COG0372	Belongs to the citrate synthase family
F9230_RS08385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9230_RS08390	COG0730	response to heat
F9230_RS08415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9230_RS08420	COG1944	ATP diphosphatase activity
F9230_RS08425	COG2207	Transcriptional regulator
F9230_RS08430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9230_RS08435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F9230_RS08465	COG2223	nitrite transmembrane transporter activity
F9230_RS08480	COG1346	cytolysis
F9230_RS08485	COG1380	Effector of murein hydrolase LrgA
F9230_RS08490	COG0583	DNA-binding transcription factor activity
F9230_RS08495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9230_RS08520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F9230_RS08665	COG4383	Mu-like prophage protein gp29
F9230_RS08810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_RS08840	COG1846	Transcriptional regulator
F9230_RS08845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9230_RS08920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9230_RS08925	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F9230_RS08940	COG3300	MHYT domain
F9230_RS08940	COG5001	Diguanylate cyclase
F9230_RS08945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9230_RS08955	COG2814	Major facilitator Superfamily
F9230_RS08970	COG1132	(ABC) transporter
F9230_RS08980	COG0668	transmembrane transport
F9230_RS08985	COG3122	Protein conserved in bacteria
F9230_RS09005	COG0640	Transcriptional regulator
F9230_RS09010	COG0596	Alpha beta hydrolase
F9230_RS09015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_RS09020	COG1335	isochorismatase
F9230_RS09025	COG0251	oxidation-reduction process
F9230_RS09030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_RS09035	COG2233	PERMEase
F9230_RS09045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9230_RS09055	COG0183	Belongs to the thiolase family
F9230_RS09060	COG0583	DNA-binding transcription factor activity
F9230_RS09075	COG0439	Biotin carboxylase
F9230_RS09090	COG0511	ligase activity, forming carbon-carbon bonds
F9230_RS09100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9230_RS09105	COG0183	Belongs to the thiolase family
F9230_RS09110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_RS09115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9230_RS09120	COG3135	benzoate transporter
F9230_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS09130	COG0543	2 iron, 2 sulfur cluster binding
F9230_RS09130	COG0633	Ferredoxin
F9230_RS09135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F9230_RS09140	COG4638	Rieske (2fe-2S)
F9230_RS09150	COG4829	muconolactone delta-isomerase
F9230_RS09155	COG4948	Mandelate Racemase Muconate Lactonizing
F9230_RS09160	COG0583	DNA-binding transcription factor activity
F9230_RS09165	COG2814	Major facilitator Superfamily
F9230_RS09265	COG0583	DNA-binding transcription factor activity
F9230_RS09275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9230_RS09280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9230_RS09285	COG0022	dehydrogenase e1 component
F9230_RS09290	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9230_RS09295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9230_RS09305	COG1063	alcohol dehydrogenase
F9230_RS09310	COG4628	conserved protein (DUF2132)
F9230_RS09440	COG0596	Alpha beta hydrolase
F9230_RS09510	COG0864	Transcriptional regulator
F9230_RS09535	COG2814	Major facilitator Superfamily
F9230_RS09590	COG1960	acyl-CoA dehydrogenase activity
F9230_RS09595	COG1960	acyl-CoA dehydrogenase activity
F9230_RS09645	COG0552	protein localization to endoplasmic reticulum
F9230_RS09650	COG0612	Peptidase, M16
F9230_RS09675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9230_RS09675	COG0517	IMP dehydrogenase activity
F9230_RS09680	COG0133	tryptophan synthase activity
F9230_RS09690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9230_RS09705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F9230_RS09710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F9230_RS09810	COG2850	peptidyl-arginine hydroxylation
F9230_RS09815	COG4585	Histidine kinase
F9230_RS09820	COG2197	response regulator
F9230_RS09825	COG0069	glutamate synthase activity
F9230_RS09845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F9230_RS09850	COG1454	alcohol dehydrogenase
F9230_RS09855	COG0824	Thioesterase
F9230_RS09860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9230_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS09890	COG0183	Belongs to the thiolase family
F9230_RS09905	COG0583	DNA-binding transcription factor activity
F9230_RS09910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F9230_RS09920	COG3135	benzoate transporter
F9230_RS09925	COG1309	transcriptional regulator
F9230_RS09930	COG2076	Multidrug Resistance protein
F9230_RS09945	COG0589	response to stress
F9230_RS09955	COG0308	aminopeptidase N
F9230_RS09980	COG1253	flavin adenine dinucleotide binding
F9230_RS10000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F9230_RS10005	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F9230_RS10020	COG2431	L-lysine efflux transmembrane transporter activity
F9230_RS10035	COG0776	regulation of translation
F9230_RS10055	COG0590	tRNA wobble adenosine to inosine editing
F9230_RS10065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F9230_RS10100	COG0084	hydrolase, TatD family'
F9230_RS10120	COG1663	tetraacyldisaccharide 4'-kinase activity
F9230_RS10125	COG1132	(ABC) transporter
F9230_RS10135	COG0811	peptide transport
F9230_RS10140	COG1475	DNA binding
F9230_RS10145	COG1192	Involved in chromosome partitioning
F9230_RS10155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F9230_RS10160	COG3178	'Phosphotransferase
F9230_RS10170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9230_RS10175	COG1923	regulation of RNA biosynthetic process
F9230_RS10185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F9230_RS10190	COG0802	atpase or kinase
F9230_RS10215	COG2707	UPF0756 membrane protein
F9230_RS10220	COG2814	Major facilitator Superfamily
F9230_RS10225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9230_RS10230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9230_RS10240	COG1454	alcohol dehydrogenase
F9230_RS10260	COG0531	amino acid
F9230_RS10265	COG4303	Ethanolamine ammonia lyase large subunit
F9230_RS10270	COG4302	ethanolamine ammonia-lyase activity
F9230_RS10280	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS10290	COG0519	Catalyzes the synthesis of GMP from XMP
F9230_RS10290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9230_RS10295	COG2353	YceI-like domain
F9230_RS10300	COG0456	acetyltransferase
F9230_RS10310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9230_RS10315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F9230_RS10370	COG0352	thiamine-phosphate diphosphorylase activity
F9230_RS10405	COG0612	Peptidase, M16
F9230_RS10415	COG1823	symporter activity
F9230_RS10420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_RS10460	COG2351	hydroxyisourate hydrolase activity
F9230_RS10470	COG1686	Belongs to the peptidase S11 family
F9230_RS10475	COG1252	NADH dehydrogenase
F9230_RS10480	COG1047	Peptidyl-prolyl cis-trans
F9230_RS10485	COG1254	Belongs to the acylphosphatase family
F9230_RS10490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9230_RS10490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9230_RS10510	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS10515	COG2819	hydrolase of the alpha beta superfamily
F9230_RS10525	COG0372	Belongs to the citrate synthase family
F9230_RS10555	COG0542	response to heat
F9230_RS10560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F9230_RS10575	COG3706	GGDEF domain
F9230_RS10585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F9230_RS10590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9230_RS10600	COG0569	domain protein
F9230_RS10605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9230_RS10625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9230_RS10635	COG1585	Membrane protein implicated in regulation of membrane protease activity
F9230_RS10650	COG1294	oxidase, subunit
F9230_RS10655	COG4890	Cyd operon protein YbgT
F9230_RS10670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9230_RS10675	COG1309	transcriptional regulator
F9230_RS10680	COG1012	belongs to the aldehyde dehydrogenase family
F9230_RS10690	COG0579	oxidoreductase
F9230_RS10705	COG0772	Belongs to the SEDS family
F9230_RS10720	COG0148	phosphopyruvate hydratase activity
F9230_RS10740	COG0583	DNA-binding transcription factor activity
F9230_RS10745	COG0656	L-ascorbic acid biosynthetic process
F9230_RS10750	COG2814	Major facilitator Superfamily
F9230_RS10765	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9230_RS10765	COG1902	pentaerythritol trinitrate reductase activity
F9230_RS10775	COG2267	carboxylic ester hydrolase activity
F9230_RS10785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9230_RS10790	COG0702	epimerase
F9230_RS10830	COG1011	Hydrolase
F9230_RS10835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F9230_RS10840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F9230_RS10845	COG2137	regulation of response to DNA damage stimulus
F9230_RS10860	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9230_RS10880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9230_RS10895	COG0575	Belongs to the CDS family
F9230_RS10900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F9230_RS10920	COG3852	Histidine kinase
F9230_RS10935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9230_RS10940	COG0583	DNA-binding transcription factor activity
F9230_RS10945	COG0024	Methionine aminopeptidase
F9230_RS10970	COG1113	amino acid transport
F9230_RS10980	COG0786	glutamate:sodium symporter activity
F9230_RS10985	COG4773	Receptor
F9230_RS11030	COG0729	surface antigen
F9230_RS11055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F9230_RS11070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9230_RS11075	COG1960	acyl-CoA dehydrogenase activity
F9230_RS11105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_RS11110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9230_RS11115	COG2890	protein-(glutamine-N5) methyltransferase activity
F9230_RS11120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F9230_RS11135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_RS11165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9230_RS11170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9230_RS11175	COG1845	cytochrome c oxidase, subunit III
F9230_RS11180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F9230_RS11200	COG0360	Binds together with S18 to 16S ribosomal RNA
F9230_RS11215	COG0305	Participates in initiation and elongation during chromosome replication
F9230_RS11220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F9230_RS11235	COG1305	Transglutaminase-like
F9230_RS11245	COG2308	Evidence 4 Homologs of previously reported genes of
F9230_RS11260	COG0445	tRNA wobble uridine modification
F9230_RS11290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9230_RS11295	COG0138	bifunctional purine biosynthesis protein purh
F9230_RS11300	COG0151	Belongs to the GarS family
F9230_RS11310	COG1024	Enoyl-CoA hydratase
F9230_RS11310	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9230_RS11320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9230_RS11325	COG2011	ABC-type metal ion transport system permease component
F9230_RS11365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F9230_RS11375	COG4122	O-methyltransferase activity
F9230_RS11395	COG1137	ATPase activity
F9230_RS11400	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F9230_RS11410	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F9230_RS11415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9230_RS11415	COG0517	IMP dehydrogenase activity
F9230_RS11425	COG0406	alpha-ribazole phosphatase activity
F9230_RS11430	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F9230_RS11465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9230_RS11475	COG0243	molybdopterin cofactor binding
F9230_RS11480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_RS11485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_RS11490	COG2223	nitrite transmembrane transporter activity
F9230_RS11500	COG1116	anion transmembrane transporter activity
F9230_RS11500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_RS11520	COG1643	Atp-dependent helicase
F9230_RS11530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9230_RS11570	COG2815	serine threonine protein kinase
F9230_RS11570	COG0515	serine threonine protein kinase
F9230_RS11585	COG1335	isochorismatase
F9230_RS11600	COG1610	YqeY-like protein
F9230_RS11605	COG4783	chaperone-mediated protein folding
F9230_RS11660	COG0778	Nitroreductase
F9230_RS11670	COG0513	Belongs to the DEAD box helicase family
F9230_RS11675	COG1278	Cold shock
F9230_RS11690	COG2363	Small membrane protein
F9230_RS11715	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9230_RS11720	COG0625	glutathione transferase activity
F9230_RS11725	COG0659	secondary active sulfate transmembrane transporter activity
F9230_RS11735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9230_RS11765	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS11770	COG1309	transcriptional regulator
F9230_RS11775	COG1960	acyl-CoA dehydrogenase activity
F9230_RS11780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9230_RS11790	COG4770	biotin carboxylase activity
F9230_RS11805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_RS11810	COG2031	fatty acid transporter
F9230_RS11830	COG0540	Belongs to the ATCase OTCase family
F9230_RS11855	COG1765	OsmC-like protein
F9230_RS11865	COG0667	Aldo Keto reductase
F9230_RS11880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9230_RS11895	COG1522	sequence-specific DNA binding
F9230_RS11900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9230_RS11915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9230_RS11925	COG0527	aspartate kinase activity
F9230_RS11935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F9230_RS11950	COG3038	cytochrome b561
F9230_RS11960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F9230_RS11965	COG2252	PERMEase
F9230_RS11975	COG0415	Belongs to the DNA photolyase family
F9230_RS12005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F9230_RS12010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F9230_RS12020	COG0693	protein deglycase activity
F9230_RS12025	COG1960	acyl-CoA dehydrogenase activity
F9230_RS12030	COG1301	dicarboxylic acid transport
F9230_RS12035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F9230_RS12045	COG3139	Protein of unknown function (DUF1315)
F9230_RS12050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F9230_RS12055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F9230_RS12065	COG0494	nUDIX hydrolase
F9230_RS12075	COG0642	Histidine kinase
F9230_RS12090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F9230_RS12100	COG1720	tRNA m6t6A37 methyltransferase activity
F9230_RS12170	COG0826	peptidase U32
F9230_RS12175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9230_RS12200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9230_RS12245	COG3706	GGDEF domain
F9230_RS12250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9230_RS12250	COG0475	glutathione-regulated potassium exporter activity
F9230_RS12255	COG0697	spore germination
F9230_RS12260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_RS12265	COG0235	Class ii aldolase
F9230_RS12305	COG4149	molybdate abc transporter
F9230_RS12310	COG0725	ABC transporter, periplasmic molybdate-binding protein
F9230_RS12320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F9230_RS12325	COG0243	molybdopterin cofactor binding
F9230_RS12330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9230_RS12335	COG0315	cyclic pyranopterin monophosphate synthase activity
F9230_RS12335	COG0521	Mo-molybdopterin cofactor biosynthetic process
F9230_RS12340	COG0303	'Molybdopterin
F9230_RS12355	COG1131	(ABC) transporter
F9230_RS12360	COG0842	Transport permease protein
F9230_RS12375	COG2951	lytic endotransglycosylase activity
F9230_RS12410	COG0052	Belongs to the universal ribosomal protein uS2 family
F9230_RS12430	COG2175	clavaminate synthase activity
F9230_RS12445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_RS12450	COG0842	Transport permease protein
F9230_RS12485	COG1280	lysine exporter protein (LysE YggA)
F9230_RS12490	COG1522	sequence-specific DNA binding
F9230_RS12495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9230_RS12505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F9230_RS12515	COG0019	diaminopimelate decarboxylase activity
F9230_RS12525	COG1113	amino acid transport
F9230_RS12530	COG1115	amino acid carrier protein
F9230_RS12545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9230_RS12550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9230_RS12555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9230_RS12560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9230_RS12600	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F9230_RS12605	COG3161	chorismate lyase activity
F9230_RS12615	COG0174	glutamine synthetase
F9230_RS12620	COG0512	Glutamine amidotransferase of anthranilate synthase
F9230_RS12625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F9230_RS12630	COG0134	indole-3-glycerol-phosphate synthase activity
F9230_RS12645	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS12660	COG0302	gtp cyclohydrolase
F9230_RS12670	COG3706	GGDEF domain
F9230_RS12685	COG3739	integral membrane protein
F9230_RS12705	COG1741	Belongs to the pirin family
F9230_RS12720	COG1309	transcriptional regulator
F9230_RS12750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9230_RS12755	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F9230_RS12765	COG0037	tRNA processing
F9230_RS12770	COG0741	lytic transglycosylase activity
F9230_RS12775	COG0501	Belongs to the peptidase M48B family
F9230_RS12790	COG2239	Acts as a magnesium transporter
F9230_RS12820	COG1253	flavin adenine dinucleotide binding
F9230_RS12825	COG2851	Citrate transporter
F9230_RS12865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9230_RS12870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9230_RS12895	COG0505	Belongs to the CarA family
F9230_RS12900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F9230_RS12910	COG0110	maltose O-acetyltransferase activity
F9230_RS12925	COG3695	enzyme binding
F9230_RS12940	COG2321	neutral zinc metallopeptidase
F9230_RS12945	COG2354	Protein conserved in bacteria
F9230_RS12960	COG2268	Band 7 protein
F9230_RS12970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F9230_RS12980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9230_RS12995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F9230_RS13000	COG1053	succinate dehydrogenase
F9230_RS13005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F9230_RS13010	COG2009	succinate dehydrogenase
F9230_RS13020	COG2072	flavoprotein involved in K transport
F9230_RS13040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F9230_RS13040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9230_RS13065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9230_RS13090	COG0564	pseudouridine synthase activity
F9230_RS13100	COG0358	DNA primase activity
F9230_RS13115	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F9230_RS13145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9230_RS13150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F9230_RS13175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9230_RS13200	COG0586	Pfam SNARE associated Golgi protein
F9230_RS13215	COG1280	lysine exporter protein (LysE YggA)
F9230_RS13235	COG2921	Belongs to the UPF0250 family
F9230_RS13240	COG0321	lipoyl(octanoyl) transferase activity
F9230_RS13255	COG0531	amino acid
F9230_RS13275	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F9230_RS13280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9230_RS13280	COG1648	precorrin-2 dehydrogenase activity
F9230_RS13285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F9230_RS13295	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F9230_RS13305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F9230_RS13325	COG0671	phosphoesterase, PA-phosphatase related
F9230_RS13330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_RS13340	COG1538	Outer membrane efflux protein
F9230_RS13345	COG0393	Putative heavy-metal-binding
F9230_RS13350	COG0393	Putative heavy-metal-binding
F9230_RS13360	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS13370	COG0525	valine-tRNA ligase activity
F9230_RS13385	COG2852	Protein conserved in bacteria
F9230_RS13405	COG0583	DNA-binding transcription factor activity
F9230_RS13410	COG1278	Cold shock
F9230_RS13415	COG1278	Cold shock
F9230_RS13430	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9230_RS13435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9230_RS13440	COG0713	ATP synthesis coupled electron transport
F9230_RS13450	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9230_RS13465	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F9230_RS13485	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9230_RS13495	COG2205	protein histidine kinase activity
F9230_RS13500	COG0745	RESPONSE REGULATOR receiver
F9230_RS13515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9230_RS13570	COG0439	Biotin carboxylase
F9230_RS13575	COG1802	Transcriptional regulator
F9230_RS13580	COG1652	LysM domain
F9230_RS13590	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS13605	COG1399	metal-binding, possibly nucleic acid-binding protein
F9230_RS13610	COG3101	peptidyl-lysine hydroxylation
F9230_RS13615	COG0009	L-threonylcarbamoyladenylate synthase
F9230_RS13625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F9230_RS13630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F9230_RS13700	COG4106	trans-aconitate 2-methyltransferase activity
F9230_RS13715	COG2226	methyltransferase
F9230_RS13715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9230_RS13715	COG0596	Alpha beta hydrolase
F9230_RS13720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9230_RS13725	COG2193	ferroxidase activity
F9230_RS13750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9230_RS13755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F9230_RS13760	COG3115	cell septum assembly
F9230_RS13765	COG1196	nuclear chromosome segregation
F9230_RS13775	COG0730	response to heat
F9230_RS13785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F9230_RS13795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9230_RS13810	COG0488	(ABC) transporter
F9230_RS13835	COG3422	double-strand break repair
F9230_RS13845	COG2824	Alkylphosphonate utilization operon protein PhnA
F9230_RS13850	COG3189	MarR family transcriptional regulator
F9230_RS13870	COG0564	pseudouridine synthase activity
F9230_RS13875	COG0346	lactoylglutathione lyase activity
F9230_RS13920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F9230_RS13955	COG1902	pentaerythritol trinitrate reductase activity
F9230_RS13960	COG3659	wide pore channel activity
F9230_RS13970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9230_RS13980	COG1970	mechanosensitive ion channel activity
F9230_RS13985	COG1217	gtp-binding protein TYPA
F9230_RS13990	COG2233	PERMEase
F9230_RS13995	COG2813	Specifically methylates the guanine in position
F9230_RS14000	COG0833	amino acid
F9230_RS14015	COG0183	Belongs to the thiolase family
F9230_RS14035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_RS14050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9230_RS14055	COG2207	Transcriptional regulator
F9230_RS14060	COG0183	Belongs to the thiolase family
F9230_RS14065	COG1024	Enoyl-CoA hydratase
F9230_RS14065	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9230_RS14085	COG1272	protein, Hemolysin III
F9230_RS14090	COG0477	Major facilitator Superfamily
F9230_RS14100	COG1408	metallophosphoesterase
F9230_RS14105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9230_RS14115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9230_RS14140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F9230_RS14145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9230_RS14150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F9230_RS14155	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F9230_RS14160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F9230_RS14170	COG0625	glutathione transferase activity
F9230_RS14175	COG2969	positive regulation of protein catabolic process
F9230_RS14230	COG2853	Lipoprotein
F9230_RS14235	COG2208	phosphoserine phosphatase activity
F9230_RS14245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9230_RS14250	COG1764	response to oxidative stress
F9230_RS14280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9230_RS14280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9230_RS14295	COG0037	tRNA processing
F9230_RS14305	COG0248	Ppx GppA phosphatase
F9230_RS14330	COG0072	phenylalanine-tRNA ligase activity
F9230_RS14375	COG1238	metal cluster binding
F9230_RS14385	COG0625	glutathione transferase activity
F9230_RS14395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F9230_RS14405	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS14410	COG3028	Belongs to the UPF0307 family
F9230_RS14420	COG1660	Displays ATPase and GTPase activities
F9230_RS14425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F9230_RS14435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9230_RS14440	COG0617	tRNA 3'-terminal CCA addition
F9230_RS14445	COG1555	photosystem II stabilization
F9230_RS14450	COG3956	TIGRFAM MazG family protein
F9230_RS14460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9230_RS14475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9230_RS14480	COG5002	protein histidine kinase activity
F9230_RS14480	COG2205	protein histidine kinase activity
F9230_RS14480	COG0784	Response regulator, receiver
F9230_RS14485	COG1024	Enoyl-CoA hydratase
F9230_RS14490	COG2084	Dehydrogenase
F9230_RS14495	COG3622	Belongs to the hyi family
F9230_RS14510	COG0004	ammonium transporteR
F9230_RS14535	COG2814	Major facilitator Superfamily
F9230_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS14550	COG0641	radical SAM
F9230_RS14555	COG0641	radical SAM
F9230_RS14560	COG3119	arylsulfatase activity
F9230_RS14645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9230_RS14655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F9230_RS14665	COG0084	hydrolase, TatD family'
F9230_RS14680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9230_RS14695	COG0793	Belongs to the peptidase S41A family
F9230_RS14720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9230_RS14725	COG0280	phosphate acetyltransferase
F9230_RS14725	COG0857	belongs to the CobB CobQ family
F9230_RS14750	COG2207	Transcriptional regulator
F9230_RS14750	COG1917	Cupin 2, conserved barrel domain protein
F9230_RS14755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F9230_RS14755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F9230_RS14775	COG0740	serine-type endopeptidase activity
F9230_RS14785	COG4771	TonB-dependent receptor
F9230_RS14790	COG4774	siderophore transport
F9230_RS14805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9230_RS14815	COG2813	Specifically methylates the guanine in position
F9230_RS14815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9230_RS14920	COG0788	formyltetrahydrofolate deformylase activity
F9230_RS14945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9230_RS14945	COG4651	solute:proton antiporter activity
F9230_RS14970	COG0210	DNA helicase
F9230_RS14975	COG1929	Belongs to the glycerate kinase type-1 family
F9230_RS15015	COG2900	Belongs to the SlyX family
F9230_RS15020	COG0488	(ABC) transporter
F9230_RS15030	COG1560	Kdo2-lipid A biosynthetic process
F9230_RS15080	COG0473	3-isopropylmalate dehydrogenase activity
F9230_RS15095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F9230_RS15105	COG0583	DNA-binding transcription factor activity
F9230_RS15140	COG1280	lysine exporter protein (LysE YggA)
F9230_RS15155	COG1960	acyl-CoA dehydrogenase activity
F9230_RS15190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F9230_RS15195	COG0583	DNA-binding transcription factor activity
F9230_RS15210	COG0564	pseudouridine synthase activity
F9230_RS15215	COG1530	ribonuclease E activity
F9230_RS15220	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS15245	COG1983	PspC domain protein
F9230_RS15265	COG0751	glycine-tRNA ligase activity
F9230_RS15290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9230_RS15305	COG2226	methyltransferase
F9230_RS15320	COG0493	'glutamate synthase
F9230_RS15320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9230_RS15330	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F9230_RS15335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9230_RS15340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F9230_RS15350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F9230_RS15360	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F9230_RS15360	COG0644	oxidoreductase
F9230_RS15380	COG0425	Belongs to the sulfur carrier protein TusA family
F9230_RS15385	COG4535	Mg2 and Co2 transporter CorC
F9230_RS15390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F9230_RS15395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9230_RS15415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F9230_RS15425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F9230_RS15445	COG2841	Protein conserved in bacteria
F9230_RS15450	COG0598	Magnesium transport protein CorA
F9230_RS15455	COG1185	polyribonucleotide nucleotidyltransferase activity
F9230_RS15465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F9230_RS15470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9230_RS15475	COG1074	ATP-dependent DNA helicase activity
F9230_RS15480	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F9230_RS15510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9230_RS15525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F9230_RS15535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F9230_RS15540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9230_RS15540	COG2111	Na H antiporter
F9230_RS15545	COG1006	Multisubunit Na H antiporter MnhC subunit
F9230_RS15550	COG0651	ATP synthesis coupled electron transport
F9230_RS15555	COG1863	multisubunit Na H antiporter MnhE subunit
F9230_RS15560	COG2212	antiporter activity
F9230_RS15565	COG1320	monovalent cation:proton antiporter activity
F9230_RS15570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F9230_RS15580	COG0195	Participates in both transcription termination and antitermination
F9230_RS15640	COG0237	dephospho-CoA kinase activity
F9230_RS15650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9230_RS15660	COG0497	DNA recombination
F9230_RS15665	COG1678	Uncharacterized ACR, COG1678
F9230_RS15670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F9230_RS15685	COG1289	transmembrane transporter activity
F9230_RS15700	COG1132	(ABC) transporter
F9230_RS15705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F9230_RS15775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F9230_RS15805	COG0326	Molecular chaperone. Has ATPase activity
F9230_RS15815	COG3047	cAMP biosynthetic process
F9230_RS15820	COG2056	Na+-H+ antiporter family
F9230_RS15845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F9230_RS15850	COG0085	RNA polymerase activity
F9230_RS15855	COG0222	ribosome binding
F9230_RS15860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F9230_RS15865	COG0081	regulation of translation
F9230_RS15870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F9230_RS15920	COG0546	phosphoglycolate phosphatase activity
F9230_RS15950	COG0824	Thioesterase
F9230_RS15970	COG0181	hydroxymethylbilane synthase activity
F9230_RS15980	COG3275	phosphorelay sensor kinase activity
F9230_RS16000	COG1538	Outer membrane efflux protein
F9230_RS16010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F9230_RS16020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9230_RS16025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9230_RS16030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9230_RS16035	COG0772	Belongs to the SEDS family
F9230_RS16040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F9230_RS16060	COG4974	Belongs to the 'phage' integrase family
F9230_RS16065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9230_RS16075	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F9230_RS16080	COG1686	Belongs to the peptidase S11 family
F9230_RS16085	COG2197	response regulator
F9230_RS16100	COG0793	Belongs to the peptidase S41A family
F9230_RS16105	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F9230_RS16110	COG0795	lipopolysaccharide-transporting ATPase activity
F9230_RS16115	COG0795	lipopolysaccharide-transporting ATPase activity
F9230_RS16135	COG0586	Pfam SNARE associated Golgi protein
F9230_RS16150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9230_RS16150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9230_RS16160	COG0004	ammonium transporteR
F9230_RS16165	COG0347	Belongs to the P(II) protein family
F9230_RS16175	COG0606	chelatase, subunit chli
F9230_RS16195	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9230_RS16210	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_RS16220	COG0477	Major facilitator Superfamily
F9230_RS16225	COG2860	membrane
F9230_RS16230	COG3012	SEC-C Motif Domain Protein
F9230_RS16235	COG1253	flavin adenine dinucleotide binding
F9230_RS16255	COG2814	Major facilitator Superfamily
F9230_RS16265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9230_RS16340	COG0758	DNA mediated transformation
F9230_RS16350	COG0697	spore germination
F9230_RS16360	COG0386	Belongs to the glutathione peroxidase family
F9230_RS16400	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F9230_RS16450	COG1121	(ABC) transporter
F9230_RS16455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9230_RS16460	COG1683	Conserved Protein
F9230_RS16470	COG2837	iron assimilation
F9230_RS16480	COG1876	peptidase activity
F9230_RS16490	COG0281	malic enzyme
F9230_RS16535	COG1715	Restriction endonuclease
F9230_RS16540	COG0519	Catalyzes the synthesis of GMP from XMP
F9230_RS16540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9230_RS16550	COG2259	Doxx family
F9230_RS16555	COG0586	Pfam SNARE associated Golgi protein
F9230_RS16570	COG1192	Involved in chromosome partitioning
F9230_RS16580	COG0271	Belongs to the BolA IbaG family
F9230_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS16650	COG2986	histidine ammonia-lyase
F9230_RS16665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F9230_RS16675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F9230_RS16695	COG0583	DNA-binding transcription factor activity
F9230_RS16700	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9230_RS16715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F9230_RS16725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F9230_RS16730	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F9230_RS16740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9230_RS16745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9230_RS16750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9230_RS16765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F9230_RS16775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F9230_RS16785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F9230_RS16825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F9230_RS16830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F9230_RS16835	COG1596	polysaccharide export
F9230_RS16860	COG0728	peptidoglycan biosynthetic process
F9230_RS16865	COG3023	N-Acetylmuramoyl-L-alanine amidase
F9230_RS16875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F9230_RS16885	COG3307	-O-antigen
F9230_RS16895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9230_RS16900	COG0546	phosphoglycolate phosphatase activity
F9230_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_RS16930	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F9230_RS16930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F9230_RS16935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_RS16940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_RS16945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_RS16950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9230_RS16955	COG1116	anion transmembrane transporter activity
F9230_RS16960	COG1309	transcriptional regulator
F9230_RS16975	COG0196	riboflavin kinase activity
F9230_RS16980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F9230_RS16985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F9230_RS16990	COG1047	Peptidyl-prolyl cis-trans
F9230_RS17010	COG2133	pyrroloquinoline quinone binding
F9230_RS17040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9230_RS17045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F9230_RS17050	COG2951	lytic endotransglycosylase activity
F9230_RS17055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9230_RS17070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9230_RS17090	COG0861	Integral membrane protein TerC family
F9230_RS17100	COG0754	glutathionylspermidine amidase activity
F9230_RS17110	COG0402	S-adenosylhomocysteine deaminase activity
F9230_RS17130	COG1230	cation diffusion facilitator family transporter
F9230_RS17145	COG0583	DNA-binding transcription factor activity
F9230_RS17160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F9230_RS17165	COG0281	malic enzyme
F9230_RS17175	COG0706	membrane insertase activity
F9230_RS17180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane