locus-tag	class	description
FYN22_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYN22_RS00010	COG0592	DNA-directed DNA polymerase activity
FYN22_RS00020	COG0187	DNA topoisomerase II activity
FYN22_RS00030	COG0488	(ABC) transporter
FYN22_RS00055	COG3385	transposase activity
FYN22_RS00095	COG0657	acetylesterase activity
FYN22_RS00105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYN22_RS00135	COG2814	Major facilitator Superfamily
FYN22_RS00145	COG0733	neurotransmitter:sodium symporter activity
FYN22_RS00165	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FYN22_RS00165	COG3266	domain, Protein
FYN22_RS00165	COG4932	domain protein
FYN22_RS00180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYN22_RS00180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYN22_RS00195	COG0129	dihydroxy-acid dehydratase activity
FYN22_RS00205	COG4774	siderophore transport
FYN22_RS00215	COG0583	DNA-binding transcription factor activity
FYN22_RS00220	COG2233	PERMEase
FYN22_RS00230	COG1309	transcriptional regulator
FYN22_RS00250	COG0484	heat shock protein binding
FYN22_RS00260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FYN22_RS00275	COG0436	Aminotransferase
FYN22_RS00280	COG1064	alcohol dehydrogenase
FYN22_RS00285	COG2818	Glycosylase
FYN22_RS00315	COG5487	UPF0391 membrane protein
FYN22_RS00320	COG2983	Belongs to the UPF0260 family
FYN22_RS00325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYN22_RS00345	COG4160	amino acid transport
FYN22_RS00350	COG4215	(ABC) transporter
FYN22_RS00375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYN22_RS00380	COG1335	isochorismatase
FYN22_RS00385	COG0385	Bile acid
FYN22_RS00415	COG3385	transposase activity
FYN22_RS00460	COG0534	Mate efflux family protein
FYN22_RS00465	COG0436	Aminotransferase
FYN22_RS00470	COG2733	membrane
FYN22_RS00485	COG2918	glutathione biosynthetic process
FYN22_RS00490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FYN22_RS00500	COG3150	esterase
FYN22_RS00565	COG3385	transposase activity
FYN22_RS00595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FYN22_RS00610	COG1393	Belongs to the ArsC family
FYN22_RS00615	COG0708	Exodeoxyribonuclease III
FYN22_RS00625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYN22_RS00640	COG1846	Transcriptional regulator
FYN22_RS00645	COG0386	Belongs to the glutathione peroxidase family
FYN22_RS00650	COG0189	ligase activity
FYN22_RS00660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYN22_RS00670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYN22_RS00680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FYN22_RS00705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYN22_RS00710	COG2119	membrane
FYN22_RS00715	COG0426	domain, Protein
FYN22_RS00715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_RS00740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYN22_RS00765	COG1902	pentaerythritol trinitrate reductase activity
FYN22_RS00770	COG1519	Transferase
FYN22_RS00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYN22_RS00780	COG0668	transmembrane transport
FYN22_RS00785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYN22_RS00790	COG0307	riboflavin synthase, alpha
FYN22_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS00810	COG0431	NADPH-dependent FMN reductase
FYN22_RS00825	COG2205	protein histidine kinase activity
FYN22_RS00825	COG0784	Response regulator, receiver
FYN22_RS00830	COG3162	membrane
FYN22_RS00835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYN22_RS00845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYN22_RS00855	COG3706	GGDEF domain
FYN22_RS00880	COG0351	phosphomethylpyrimidine kinase
FYN22_RS00880	COG0352	thiamine-phosphate diphosphorylase activity
FYN22_RS00880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FYN22_RS00890	COG2814	Major facilitator Superfamily
FYN22_RS00895	COG0629	single-stranded DNA binding
FYN22_RS00905	COG0583	DNA-binding transcription factor activity
FYN22_RS00930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_RS00955	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYN22_RS00980	COG3158	transport of potassium into the cell
FYN22_RS01000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FYN22_RS01025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FYN22_RS01030	COG1278	Cold shock
FYN22_RS01045	COG0531	amino acid
FYN22_RS01050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYN22_RS01085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FYN22_RS01120	COG0427	acetyl-CoA hydrolase
FYN22_RS01150	COG4221	oxidoreductase activity
FYN22_RS01155	COG2873	o-acetylhomoserine
FYN22_RS01160	COG0488	(ABC) transporter
FYN22_RS01165	COG3385	transposase activity
FYN22_RS01185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYN22_RS01195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYN22_RS01200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYN22_RS01220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYN22_RS01225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FYN22_RS01235	COG2226	methyltransferase
FYN22_RS01285	COG0069	glutamate synthase activity
FYN22_RS01285	COG0067	glutamate synthase
FYN22_RS01285	COG0070	glutamate synthase
FYN22_RS01290	COG0493	'glutamate synthase
FYN22_RS01300	COG1704	LemA family
FYN22_RS01305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYN22_RS01320	COG3307	-O-antigen
FYN22_RS01350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYN22_RS01355	COG1758	RNA polymerase activity
FYN22_RS01360	COG0194	GDP metabolic process
FYN22_RS01405	COG0228	four-way junction DNA binding
FYN22_RS01410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYN22_RS01420	COG0335	large ribosomal subunit rRNA binding
FYN22_RS01435	COG5380	lipid catabolic process
FYN22_RS01440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYN22_RS01460	COG5006	permease, DMT superfamily
FYN22_RS01465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYN22_RS01470	COG0277	FAD linked oxidase domain protein
FYN22_RS01495	COG2814	Major facilitator Superfamily
FYN22_RS01500	COG1289	transmembrane transporter activity
FYN22_RS01505	COG2032	superoxide dismutase activity
FYN22_RS01510	COG0628	permease
FYN22_RS01515	COG1192	Involved in chromosome partitioning
FYN22_RS01525	COG2226	methyltransferase
FYN22_RS01540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYN22_RS01545	COG0254	rRNA binding
FYN22_RS01550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYN22_RS01560	COG0534	Mate efflux family protein
FYN22_RS01570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYN22_RS01595	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS01615	COG0408	coproporphyrinogen oxidase activity
FYN22_RS01620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYN22_RS01640	COG0513	Belongs to the DEAD box helicase family
FYN22_RS01645	COG1127	ABC transporter
FYN22_RS01650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYN22_RS01655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYN22_RS01660	COG2854	intermembrane phospholipid transfer
FYN22_RS01670	COG0598	Magnesium transport protein CorA
FYN22_RS01680	COG0494	nUDIX hydrolase
FYN22_RS01685	COG1040	competence protein
FYN22_RS01690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYN22_RS01710	COG2937	Belongs to the GPAT DAPAT family
FYN22_RS01715	COG1946	Acyl-CoA thioesterase
FYN22_RS01720	COG1301	dicarboxylic acid transport
FYN22_RS01735	COG1959	2 iron, 2 sulfur cluster binding
FYN22_RS01745	COG0433	COG0433 Predicted ATPase
FYN22_RS01765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYN22_RS01770	COG0088	Forms part of the polypeptide exit tunnel
FYN22_RS01785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYN22_RS01835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYN22_RS01840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYN22_RS01850	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYN22_RS01875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYN22_RS01890	COG0202	RNA polymerase activity
FYN22_RS01895	COG0203	ribosomal protein L17
FYN22_RS01900	COG2072	flavoprotein involved in K transport
FYN22_RS01910	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS01915	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYN22_RS01945	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FYN22_RS01950	COG0339	signal peptide processing
FYN22_RS01955	COG2720	vancomycin resistance protein
FYN22_RS01960	COG0557	exoribonuclease II activity
FYN22_RS01995	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYN22_RS02010	COG1295	ribonuclease BN
FYN22_RS02050	COG4773	Receptor
FYN22_RS02060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYN22_RS02065	COG1702	phosphate starvation-inducible protein PhoH
FYN22_RS02070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYN22_RS02075	COG0739	heme binding
FYN22_RS02075	COG0741	lytic transglycosylase activity
FYN22_RS02075	COG1196	nuclear chromosome segregation
FYN22_RS02085	COG0039	L-malate dehydrogenase activity
FYN22_RS02110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYN22_RS02115	COG1183	phosphatidylcholine synthase activity
FYN22_RS02175	COG1607	acyl-coa hydrolase
FYN22_RS02190	COG1666	GTP binding
FYN22_RS02210	COG2350	Protein conserved in bacteria
FYN22_RS02220	COG0613	PHP domain protein
FYN22_RS02225	COG3781	membrane
FYN22_RS02235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYN22_RS02260	COG1162	GTPase activity
FYN22_RS02265	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYN22_RS02290	COG1538	Outer membrane efflux protein
FYN22_RS02295	COG1136	(ABC) transporter
FYN22_RS02295	COG0577	efflux transmembrane transporter activity
FYN22_RS02300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_RS02325	COG0028	Belongs to the TPP enzyme family
FYN22_RS02330	COG0440	acetolactate synthase activity
FYN22_RS02390	COG1426	Protein conserved in bacteria
FYN22_RS02410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYN22_RS02435	COG1862	Preprotein translocase
FYN22_RS02445	COG1704	LemA family
FYN22_RS02455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYN22_RS02465	COG5002	protein histidine kinase activity
FYN22_RS02470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYN22_RS02500	COG0438	transferase activity, transferring glycosyl groups
FYN22_RS02520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FYN22_RS02565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYN22_RS02595	COG3223	Belongs to the PsiE family
FYN22_RS02600	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS02605	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS02615	COG2205	protein histidine kinase activity
FYN22_RS02620	COG0745	RESPONSE REGULATOR receiver
FYN22_RS02625	COG1113	amino acid transport
FYN22_RS02630	COG2315	Protein conserved in bacteria
FYN22_RS02635	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYN22_RS02655	COG2096	Adenosyltransferase
FYN22_RS02660	COG4206	TonB-dependent receptor
FYN22_RS02685	COG3083	sulfuric ester hydrolase activity
FYN22_RS02715	COG0285	dihydrofolate synthase activity
FYN22_RS02735	COG0450	alkyl hydroperoxide reductase
FYN22_RS02755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYN22_RS02760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FYN22_RS02790	COG2199	diguanylate cyclase activity
FYN22_RS02850	COG2969	positive regulation of protein catabolic process
FYN22_RS02855	COG0625	glutathione transferase activity
FYN22_RS02865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYN22_RS02870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYN22_RS02875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYN22_RS02880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYN22_RS02885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYN22_RS02910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYN22_RS02920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYN22_RS02925	COG1408	metallophosphoesterase
FYN22_RS02935	COG0477	Major facilitator Superfamily
FYN22_RS02940	COG1272	protein, Hemolysin III
FYN22_RS02960	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYN22_RS02960	COG1024	Enoyl-CoA hydratase
FYN22_RS02965	COG0183	Belongs to the thiolase family
FYN22_RS02970	COG2207	Transcriptional regulator
FYN22_RS02975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYN22_RS02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_RS03010	COG0183	Belongs to the thiolase family
FYN22_RS03025	COG0833	amino acid
FYN22_RS03030	COG2813	Specifically methylates the guanine in position
FYN22_RS03035	COG2233	PERMEase
FYN22_RS03040	COG1217	gtp-binding protein TYPA
FYN22_RS03045	COG1970	mechanosensitive ion channel activity
FYN22_RS03055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYN22_RS03065	COG3659	wide pore channel activity
FYN22_RS03070	COG1902	pentaerythritol trinitrate reductase activity
FYN22_RS03100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYN22_RS03140	COG0346	lactoylglutathione lyase activity
FYN22_RS03145	COG0564	pseudouridine synthase activity
FYN22_RS03165	COG3189	MarR family transcriptional regulator
FYN22_RS03170	COG2824	Alkylphosphonate utilization operon protein PhnA
FYN22_RS03180	COG3422	double-strand break repair
FYN22_RS03200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYN22_RS03205	COG0488	(ABC) transporter
FYN22_RS03220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYN22_RS03230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYN22_RS03240	COG0730	response to heat
FYN22_RS03250	COG1196	nuclear chromosome segregation
FYN22_RS03255	COG3115	cell septum assembly
FYN22_RS03260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYN22_RS03265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYN22_RS03270	COG4774	siderophore transport
FYN22_RS03285	COG2193	ferroxidase activity
FYN22_RS03290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYN22_RS03295	COG0596	Alpha beta hydrolase
FYN22_RS03295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYN22_RS03295	COG2226	methyltransferase
FYN22_RS03310	COG4106	trans-aconitate 2-methyltransferase activity
FYN22_RS03340	COG4206	TonB-dependent receptor
FYN22_RS03380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYN22_RS03385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYN22_RS03395	COG0009	L-threonylcarbamoyladenylate synthase
FYN22_RS03400	COG3101	peptidyl-lysine hydroxylation
FYN22_RS03405	COG1399	metal-binding, possibly nucleic acid-binding protein
FYN22_RS03420	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS03430	COG1652	LysM domain
FYN22_RS03435	COG1802	Transcriptional regulator
FYN22_RS03475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FYN22_RS03485	COG0745	RESPONSE REGULATOR receiver
FYN22_RS03490	COG2205	protein histidine kinase activity
FYN22_RS03500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYN22_RS03520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FYN22_RS03535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYN22_RS03545	COG0713	ATP synthesis coupled electron transport
FYN22_RS03550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYN22_RS03555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYN22_RS03570	COG1278	Cold shock
FYN22_RS03580	COG0583	DNA-binding transcription factor activity
FYN22_RS03610	COG0525	valine-tRNA ligase activity
FYN22_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS03635	COG0393	Putative heavy-metal-binding
FYN22_RS03640	COG1538	Outer membrane efflux protein
FYN22_RS03650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_RS03655	COG0671	phosphoesterase, PA-phosphatase related
FYN22_RS03675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYN22_RS03685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYN22_RS03695	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYN22_RS03700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYN22_RS03700	COG1648	precorrin-2 dehydrogenase activity
FYN22_RS03705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FYN22_RS03725	COG0531	amino acid
FYN22_RS03740	COG0321	lipoyl(octanoyl) transferase activity
FYN22_RS03745	COG2921	Belongs to the UPF0250 family
FYN22_RS03770	COG0583	DNA-binding transcription factor activity
FYN22_RS03780	COG0586	Pfam SNARE associated Golgi protein
FYN22_RS03805	COG3385	transposase activity
FYN22_RS03840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYN22_RS03870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FYN22_RS03885	COG0358	DNA primase activity
FYN22_RS03895	COG0564	pseudouridine synthase activity
FYN22_RS03920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYN22_RS03945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYN22_RS03945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYN22_RS03965	COG2072	flavoprotein involved in K transport
FYN22_RS03975	COG2009	succinate dehydrogenase
FYN22_RS03980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYN22_RS03985	COG1053	succinate dehydrogenase
FYN22_RS03990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYN22_RS04005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_RS04015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYN22_RS04025	COG2268	Band 7 protein
FYN22_RS04030	COG1585	Membrane protein implicated in regulation of membrane protease activity
FYN22_RS04040	COG2354	Protein conserved in bacteria
FYN22_RS04045	COG2321	neutral zinc metallopeptidase
FYN22_RS04060	COG3695	enzyme binding
FYN22_RS04085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYN22_RS04090	COG0505	Belongs to the CarA family
FYN22_RS04115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYN22_RS04120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FYN22_RS04160	COG2851	Citrate transporter
FYN22_RS04165	COG1253	flavin adenine dinucleotide binding
FYN22_RS04195	COG2239	Acts as a magnesium transporter
FYN22_RS04210	COG0501	Belongs to the peptidase M48B family
FYN22_RS04215	COG0741	lytic transglycosylase activity
FYN22_RS04220	COG0037	tRNA processing
FYN22_RS04230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FYN22_RS04235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYN22_RS04265	COG1309	transcriptional regulator
FYN22_RS04280	COG1741	Belongs to the pirin family
FYN22_RS04300	COG3739	integral membrane protein
FYN22_RS04315	COG3706	GGDEF domain
FYN22_RS04325	COG0302	gtp cyclohydrolase
FYN22_RS04340	COG0134	indole-3-glycerol-phosphate synthase activity
FYN22_RS04345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYN22_RS04350	COG0512	Glutamine amidotransferase of anthranilate synthase
FYN22_RS04355	COG0174	glutamine synthetase
FYN22_RS04365	COG3161	chorismate lyase activity
FYN22_RS04370	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FYN22_RS04410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYN22_RS04415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYN22_RS04420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYN22_RS04425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYN22_RS04440	COG1115	amino acid carrier protein
FYN22_RS04445	COG1113	amino acid transport
FYN22_RS04455	COG0019	diaminopimelate decarboxylase activity
FYN22_RS04465	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYN22_RS04495	COG1522	sequence-specific DNA binding
FYN22_RS04500	COG1280	lysine exporter protein (LysE YggA)
FYN22_RS04535	COG0842	Transport permease protein
FYN22_RS04540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_RS04555	COG2175	clavaminate synthase activity
FYN22_RS04575	COG0052	Belongs to the universal ribosomal protein uS2 family
FYN22_RS04610	COG2951	lytic endotransglycosylase activity
FYN22_RS04625	COG0842	Transport permease protein
FYN22_RS04630	COG1131	(ABC) transporter
FYN22_RS04640	COG0303	'Molybdopterin
FYN22_RS04645	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYN22_RS04645	COG0315	cyclic pyranopterin monophosphate synthase activity
FYN22_RS04650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYN22_RS04655	COG0243	molybdopterin cofactor binding
FYN22_RS04660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FYN22_RS04670	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYN22_RS04675	COG4149	molybdate abc transporter
FYN22_RS04715	COG0235	Class ii aldolase
FYN22_RS04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYN22_RS04725	COG0697	spore germination
FYN22_RS04730	COG0475	glutathione-regulated potassium exporter activity
FYN22_RS04730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYN22_RS04735	COG3706	GGDEF domain
FYN22_RS04780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYN22_RS04805	COG3634	alkyl hydroperoxide reductase activity
FYN22_RS04810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYN22_RS04815	COG0826	peptidase U32
FYN22_RS04870	COG1720	tRNA m6t6A37 methyltransferase activity
FYN22_RS04880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FYN22_RS04895	COG0642	Histidine kinase
FYN22_RS04905	COG0494	nUDIX hydrolase
FYN22_RS04915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYN22_RS04920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYN22_RS04925	COG3139	Protein of unknown function (DUF1315)
FYN22_RS04940	COG1301	dicarboxylic acid transport
FYN22_RS04945	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS04950	COG0693	protein deglycase activity
FYN22_RS04960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYN22_RS04965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYN22_RS04995	COG0415	Belongs to the DNA photolyase family
FYN22_RS05005	COG2252	PERMEase
FYN22_RS05010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYN22_RS05020	COG3038	cytochrome b561
FYN22_RS05035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYN22_RS05045	COG0527	aspartate kinase activity
FYN22_RS05055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYN22_RS05070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYN22_RS05075	COG1522	sequence-specific DNA binding
FYN22_RS05090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYN22_RS05110	COG0667	Aldo Keto reductase
FYN22_RS05120	COG1765	OsmC-like protein
FYN22_RS05145	COG0540	Belongs to the ATCase OTCase family
FYN22_RS05165	COG2031	fatty acid transporter
FYN22_RS05170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_RS05185	COG4770	biotin carboxylase activity
FYN22_RS05195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYN22_RS05200	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS05205	COG1309	transcriptional regulator
FYN22_RS05210	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_RS05240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYN22_RS05250	COG0659	secondary active sulfate transmembrane transporter activity
FYN22_RS05255	COG0625	glutathione transferase activity
FYN22_RS05260	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYN22_RS05285	COG2363	Small membrane protein
FYN22_RS05300	COG1278	Cold shock
FYN22_RS05305	COG0513	Belongs to the DEAD box helicase family
FYN22_RS05315	COG0778	Nitroreductase
FYN22_RS05340	COG0167	dihydroorotate dehydrogenase activity
FYN22_RS05370	COG4783	chaperone-mediated protein folding
FYN22_RS05375	COG1610	YqeY-like protein
FYN22_RS05405	COG2815	serine threonine protein kinase
FYN22_RS05405	COG0515	serine threonine protein kinase
FYN22_RS05445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_RS05455	COG1643	Atp-dependent helicase
FYN22_RS05475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_RS05475	COG1116	anion transmembrane transporter activity
FYN22_RS05485	COG2223	nitrite transmembrane transporter activity
FYN22_RS05490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_RS05495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_RS05500	COG0243	molybdopterin cofactor binding
FYN22_RS05510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYN22_RS05545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FYN22_RS05550	COG0406	alpha-ribazole phosphatase activity
FYN22_RS05560	COG0517	IMP dehydrogenase activity
FYN22_RS05560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FYN22_RS05565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYN22_RS05575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FYN22_RS05580	COG1137	ATPase activity
FYN22_RS05600	COG4122	O-methyltransferase activity
FYN22_RS05610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FYN22_RS05650	COG2011	ABC-type metal ion transport system permease component
FYN22_RS05655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYN22_RS05665	COG0151	Belongs to the GarS family
FYN22_RS05670	COG0138	bifunctional purine biosynthesis protein purh
FYN22_RS05675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FYN22_RS05705	COG0445	tRNA wobble uridine modification
FYN22_RS05720	COG2308	Evidence 4 Homologs of previously reported genes of
FYN22_RS05730	COG1305	Transglutaminase-like
FYN22_RS05745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYN22_RS05750	COG0305	Participates in initiation and elongation during chromosome replication
FYN22_RS05765	COG0360	Binds together with S18 to 16S ribosomal RNA
FYN22_RS05785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYN22_RS05790	COG1845	cytochrome c oxidase, subunit III
FYN22_RS05795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYN22_RS05800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYN22_RS05830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYN22_RS05845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYN22_RS05850	COG2890	protein-(glutamine-N5) methyltransferase activity
FYN22_RS05860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_RS05890	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS05895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYN22_RS05915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FYN22_RS05940	COG0729	surface antigen
FYN22_RS05985	COG4773	Receptor
FYN22_RS05990	COG0786	glutamate:sodium symporter activity
FYN22_RS06000	COG1113	amino acid transport
FYN22_RS06025	COG0024	Methionine aminopeptidase
FYN22_RS06030	COG0583	DNA-binding transcription factor activity
FYN22_RS06035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYN22_RS06050	COG3852	Histidine kinase
FYN22_RS06070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYN22_RS06075	COG0575	Belongs to the CDS family
FYN22_RS06090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYN22_RS06110	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYN22_RS06135	COG2137	regulation of response to DNA damage stimulus
FYN22_RS06140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYN22_RS06145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FYN22_RS06150	COG1011	Hydrolase
FYN22_RS06185	COG3385	transposase activity
FYN22_RS06195	COG0702	epimerase
FYN22_RS06200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FYN22_RS06210	COG2267	carboxylic ester hydrolase activity
FYN22_RS06220	COG1902	pentaerythritol trinitrate reductase activity
FYN22_RS06220	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYN22_RS06235	COG2814	Major facilitator Superfamily
FYN22_RS06240	COG0656	L-ascorbic acid biosynthetic process
FYN22_RS06245	COG0583	DNA-binding transcription factor activity
FYN22_RS06265	COG0148	phosphopyruvate hydratase activity
FYN22_RS06280	COG0772	Belongs to the SEDS family
FYN22_RS06295	COG0579	oxidoreductase
FYN22_RS06305	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_RS06310	COG1309	transcriptional regulator
FYN22_RS06315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYN22_RS06330	COG4890	Cyd operon protein YbgT
FYN22_RS06335	COG1294	oxidase, subunit
FYN22_RS06350	COG1585	Membrane protein implicated in regulation of membrane protease activity
FYN22_RS06360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYN22_RS06380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYN22_RS06385	COG0569	domain protein
FYN22_RS06395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYN22_RS06400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYN22_RS06410	COG3706	GGDEF domain
FYN22_RS06425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYN22_RS06430	COG0542	response to heat
FYN22_RS06460	COG0372	Belongs to the citrate synthase family
FYN22_RS06465	COG3385	transposase activity
FYN22_RS06490	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_RS06515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYN22_RS06515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYN22_RS06525	COG1047	Peptidyl-prolyl cis-trans
FYN22_RS06530	COG1252	NADH dehydrogenase
FYN22_RS06535	COG1686	Belongs to the peptidase S11 family
FYN22_RS06545	COG2351	hydroxyisourate hydrolase activity
FYN22_RS06585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_RS06590	COG1823	symporter activity
FYN22_RS06600	COG0612	Peptidase, M16
FYN22_RS06635	COG0352	thiamine-phosphate diphosphorylase activity
FYN22_RS06680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYN22_RS06685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYN22_RS06700	COG2353	YceI-like domain
FYN22_RS06705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYN22_RS06705	COG0519	Catalyzes the synthesis of GMP from XMP
FYN22_RS06715	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS06725	COG4302	ethanolamine ammonia-lyase activity
FYN22_RS06730	COG4303	Ethanolamine ammonia lyase large subunit
FYN22_RS06735	COG0531	amino acid
FYN22_RS06755	COG1454	alcohol dehydrogenase
FYN22_RS06765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYN22_RS06770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYN22_RS06775	COG2814	Major facilitator Superfamily
FYN22_RS06780	COG2707	UPF0756 membrane protein
FYN22_RS06785	COG1187	pseudouridine synthase activity
FYN22_RS06805	COG0802	atpase or kinase
FYN22_RS06810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYN22_RS06820	COG1923	regulation of RNA biosynthetic process
FYN22_RS06825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYN22_RS06835	COG3178	'Phosphotransferase
FYN22_RS06840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYN22_RS06850	COG1192	Involved in chromosome partitioning
FYN22_RS06855	COG1475	DNA binding
FYN22_RS06860	COG0811	peptide transport
FYN22_RS06870	COG1132	(ABC) transporter
FYN22_RS06875	COG1663	tetraacyldisaccharide 4'-kinase activity
FYN22_RS06895	COG0084	hydrolase, TatD family'
FYN22_RS06930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYN22_RS06940	COG0590	tRNA wobble adenosine to inosine editing
FYN22_RS06960	COG0776	regulation of translation
FYN22_RS06975	COG2431	L-lysine efflux transmembrane transporter activity
FYN22_RS06990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYN22_RS06995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYN22_RS07015	COG1253	flavin adenine dinucleotide binding
FYN22_RS07040	COG0308	aminopeptidase N
FYN22_RS07050	COG0589	response to stress
FYN22_RS07065	COG2076	Multidrug Resistance protein
FYN22_RS07070	COG1309	transcriptional regulator
FYN22_RS07075	COG3135	benzoate transporter
FYN22_RS07085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYN22_RS07090	COG0583	DNA-binding transcription factor activity
FYN22_RS07105	COG0183	Belongs to the thiolase family
FYN22_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS07135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYN22_RS07140	COG0824	Thioesterase
FYN22_RS07145	COG1454	alcohol dehydrogenase
FYN22_RS07150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYN22_RS07170	COG0069	glutamate synthase activity
FYN22_RS07175	COG2197	response regulator
FYN22_RS07185	COG2850	peptidyl-arginine hydroxylation
FYN22_RS07195	COG0424	maF-like protein
FYN22_RS07205	COG0126	phosphoglycerate kinase activity
FYN22_RS07220	COG0697	spore germination
FYN22_RS07240	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYN22_RS07250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYN22_RS07255	COG3781	membrane
FYN22_RS07300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYN22_RS07315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYN22_RS07345	COG0316	Belongs to the HesB IscA family
FYN22_RS07350	COG0822	iron-sulfur transferase activity
FYN22_RS07360	COG1959	2 iron, 2 sulfur cluster binding
FYN22_RS07375	COG0776	regulation of translation
FYN22_RS07380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYN22_RS07410	COG0537	adenosine 5'-monophosphoramidase activity
FYN22_RS07445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYN22_RS07450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FYN22_RS07465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYN22_RS07475	COG0133	tryptophan synthase activity
FYN22_RS07480	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FYN22_RS07480	COG0517	IMP dehydrogenase activity
FYN22_RS07510	COG0612	Peptidase, M16
FYN22_RS07515	COG0552	protein localization to endoplasmic reticulum
FYN22_RS07565	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS07570	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS07615	COG2199	diguanylate cyclase activity
FYN22_RS07625	COG2814	Major facilitator Superfamily
FYN22_RS07650	COG0864	Transcriptional regulator
FYN22_RS07720	COG0596	Alpha beta hydrolase
FYN22_RS07825	COG4628	conserved protein (DUF2132)
FYN22_RS07830	COG1063	alcohol dehydrogenase
FYN22_RS07840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_RS07845	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYN22_RS07850	COG0022	dehydrogenase e1 component
FYN22_RS07855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FYN22_RS07860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYN22_RS07945	COG2814	Major facilitator Superfamily
FYN22_RS07950	COG0583	DNA-binding transcription factor activity
FYN22_RS07955	COG4948	Mandelate Racemase Muconate Lactonizing
FYN22_RS07960	COG4829	muconolactone delta-isomerase
FYN22_RS07970	COG4638	Rieske (2fe-2S)
FYN22_RS07975	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FYN22_RS07980	COG0543	2 iron, 2 sulfur cluster binding
FYN22_RS07980	COG0633	Ferredoxin
FYN22_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS07990	COG3135	benzoate transporter
FYN22_RS07995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FYN22_RS08000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_RS08005	COG0183	Belongs to the thiolase family
FYN22_RS08010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYN22_RS08020	COG0511	ligase activity, forming carbon-carbon bonds
FYN22_RS08035	COG0439	Biotin carboxylase
FYN22_RS08050	COG0583	DNA-binding transcription factor activity
FYN22_RS08055	COG0183	Belongs to the thiolase family
FYN22_RS08065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYN22_RS08075	COG2233	PERMEase
FYN22_RS08080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_RS08085	COG0251	oxidation-reduction process
FYN22_RS08090	COG1335	isochorismatase
FYN22_RS08095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYN22_RS08100	COG0596	Alpha beta hydrolase
FYN22_RS08105	COG0640	Transcriptional regulator
FYN22_RS08125	COG3122	Protein conserved in bacteria
FYN22_RS08130	COG0668	transmembrane transport
FYN22_RS08140	COG1132	(ABC) transporter
FYN22_RS08155	COG2814	Major facilitator Superfamily
FYN22_RS08165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYN22_RS08170	COG3300	MHYT domain
FYN22_RS08170	COG5001	Diguanylate cyclase
FYN22_RS08185	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FYN22_RS08190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYN22_RS08260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FYN22_RS08265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FYN22_RS08265	COG2755	lipolytic protein G-D-S-L family
FYN22_RS08380	COG4695	Portal protein
FYN22_RS08470	COG4197	protein conserved in bacteria, prophage-related
FYN22_RS08565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYN22_RS08570	COG0583	DNA-binding transcription factor activity
FYN22_RS08575	COG1380	Effector of murein hydrolase LrgA
FYN22_RS08580	COG1346	cytolysis
FYN22_RS08595	COG2223	nitrite transmembrane transporter activity
FYN22_RS08625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYN22_RS08630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYN22_RS08635	COG2207	Transcriptional regulator
FYN22_RS08640	COG1944	ATP diphosphatase activity
FYN22_RS08645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYN22_RS08670	COG0730	response to heat
FYN22_RS08675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYN22_RS08730	COG2072	flavoprotein involved in K transport
FYN22_RS08740	COG2144	transferase activity, transferring acyl groups
FYN22_RS08765	COG3604	Transcriptional regulator
FYN22_RS08785	COG2814	Major facilitator Superfamily
FYN22_RS08820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYN22_RS08825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_RS08845	COG3188	usher protein
FYN22_RS08850	COG3121	Chaperone
FYN22_RS08885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYN22_RS08895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYN22_RS08900	COG1113	amino acid transport
FYN22_RS08905	COG0697	spore germination
FYN22_RS08920	COG1064	alcohol dehydrogenase
FYN22_RS08940	COG3293	Transposase
FYN22_RS08950	COG0204	Acyl-transferase
FYN22_RS08990	COG1464	Belongs to the NlpA lipoprotein family
FYN22_RS08995	COG1464	Belongs to the NlpA lipoprotein family
FYN22_RS09000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYN22_RS09005	COG2011	ABC-type metal ion transport system permease component
FYN22_RS09010	COG0012	GTP binding
FYN22_RS09035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYN22_RS09050	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYN22_RS09075	COG0386	Belongs to the glutathione peroxidase family
FYN22_RS09080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_RS09085	COG0436	Aminotransferase
FYN22_RS09105	COG3634	alkyl hydroperoxide reductase activity
FYN22_RS09130	COG2070	2-Nitropropane dioxygenase
FYN22_RS09140	COG3038	cytochrome b561
FYN22_RS09170	COG1278	Cold shock
FYN22_RS09180	COG0604	alcohol dehydrogenase
FYN22_RS09185	COG1733	regulation of RNA biosynthetic process
FYN22_RS09260	COG1309	transcriptional regulator
FYN22_RS09285	COG0842	Transport permease protein
FYN22_RS09290	COG0842	Transport permease protein
FYN22_RS09295	COG1131	(ABC) transporter
FYN22_RS09330	COG1538	Outer membrane efflux protein
FYN22_RS09390	COG0714	Associated with various cellular activities
FYN22_RS09395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FYN22_RS09400	COG2879	small protein
FYN22_RS09405	COG1966	Carbon starvation protein
FYN22_RS09410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYN22_RS09430	COG0254	rRNA binding
FYN22_RS09450	COG1067	ATP-dependent peptidase activity
FYN22_RS09455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYN22_RS09460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYN22_RS09465	COG0616	signal peptide processing
FYN22_RS09470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYN22_RS09480	COG0573	inorganic phosphate transmembrane transporter activity
FYN22_RS09485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FYN22_RS09490	COG0076	glutamate decarboxylase activity
FYN22_RS09495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYN22_RS09505	COG4772	TonB-dependent receptor
FYN22_RS09510	COG0671	phosphoesterase, PA-phosphatase related
FYN22_RS09515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYN22_RS09525	COG1733	regulation of RNA biosynthetic process
FYN22_RS09530	COG0702	epimerase
FYN22_RS09560	COG0556	nucleotide-excision repair
FYN22_RS09575	COG2199	diguanylate cyclase activity
FYN22_RS09585	COG0436	Aminotransferase
FYN22_RS09625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYN22_RS09630	COG1381	Involved in DNA repair and RecF pathway recombination
FYN22_RS09640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYN22_RS09655	COG0681	Belongs to the peptidase S26 family
FYN22_RS09685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_RS09795	COG4387	Mu-like prophage protein GP36
FYN22_RS09830	COG4383	Mu-like prophage protein gp29
FYN22_RS10005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYN22_RS10025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYN22_RS10035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYN22_RS10050	COG4208	sulfate ABC transporter
FYN22_RS10055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYN22_RS10060	COG0583	DNA-binding transcription factor activity
FYN22_RS10080	COG0602	queuosine metabolic process
FYN22_RS10085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYN22_RS10100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYN22_RS10110	COG0583	DNA-binding transcription factor activity
FYN22_RS10115	COG2353	YceI-like domain
FYN22_RS10120	COG1056	cytidyltransferase-related domain
FYN22_RS10120	COG1051	belongs to the nudix hydrolase family
FYN22_RS10125	COG1024	Enoyl-CoA hydratase
FYN22_RS10140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYN22_RS10140	COG3323	Protein of unknown function (DUF1653)
FYN22_RS10150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYN22_RS10150	COG0047	phosphoribosylformylglycinamidine synthase activity
FYN22_RS10170	COG2255	four-way junction helicase activity
FYN22_RS10185	COG0824	Thioesterase
FYN22_RS10205	COG0823	Involved in the tonB-independent uptake of proteins
FYN22_RS10225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYN22_RS10260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYN22_RS10265	COG0628	permease
FYN22_RS10270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYN22_RS10275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FYN22_RS10295	COG2333	competence protein COMEC
FYN22_RS10295	COG0658	competence protein
FYN22_RS10300	COG1136	(ABC) transporter
FYN22_RS10305	COG4591	ABC-type transport system involved in lipoprotein release permease component
FYN22_RS10320	COG1671	Belongs to the UPF0178 family
FYN22_RS10330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_RS10335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYN22_RS10340	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS10380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FYN22_RS10385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYN22_RS10390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYN22_RS10395	COG5001	Diguanylate cyclase
FYN22_RS10395	COG1716	ATPase activity
FYN22_RS10400	COG0280	phosphate acetyltransferase
FYN22_RS10400	COG0281	malic enzyme
FYN22_RS10430	COG1024	Enoyl-CoA hydratase
FYN22_RS10435	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS10440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYN22_RS10470	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYN22_RS10470	COG1902	pentaerythritol trinitrate reductase activity
FYN22_RS10475	COG0277	FAD linked oxidase domain protein
FYN22_RS10485	COG2186	Transcriptional regulator
FYN22_RS10500	COG2203	Gaf domain
FYN22_RS10500	COG3706	GGDEF domain
FYN22_RS10500	COG4251	negative regulation of phosphorylation
FYN22_RS10500	COG5001	Diguanylate cyclase
FYN22_RS10505	COG0418	dihydroorotase activity
FYN22_RS10510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYN22_RS10520	COG0833	amino acid
FYN22_RS10535	COG0833	amino acid
FYN22_RS10555	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FYN22_RS10570	COG4172	Belongs to the ABC transporter superfamily
FYN22_RS10575	COG4239	(ABC) transporter, permease
FYN22_RS10580	COG4174	ABC transporter (Permease)
FYN22_RS10585	COG4166	transmembrane transport
FYN22_RS10590	COG1388	LysM domain
FYN22_RS10590	COG0741	lytic transglycosylase activity
FYN22_RS10595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYN22_RS10610	COG0657	acetylesterase activity
FYN22_RS10630	COG0583	DNA-binding transcription factor activity
FYN22_RS10635	COG4942	peptidase
FYN22_RS10635	COG1388	LysM domain
FYN22_RS10650	COG0753	catalase activity
FYN22_RS10680	COG1686	Belongs to the peptidase S11 family
FYN22_RS10685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FYN22_RS10705	COG2915	High frequency lysogenization protein hflD homolog
FYN22_RS10725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYN22_RS10730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYN22_RS10750	COG0006	proline dipeptidase activity
FYN22_RS10805	COG3706	GGDEF domain
FYN22_RS10820	COG1785	Belongs to the alkaline phosphatase family
FYN22_RS10825	COG1785	Belongs to the alkaline phosphatase family
FYN22_RS10845	COG4770	biotin carboxylase activity
FYN22_RS10865	COG1914	H( )-stimulated, divalent metal cation uptake system
FYN22_RS10870	COG0583	DNA-binding transcription factor activity
FYN22_RS10875	COG2217	Heavy metal translocating P-type atpase
FYN22_RS10885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYN22_RS10900	COG2234	aminopeptidase activity
FYN22_RS10910	COG3384	dioxygenase
FYN22_RS10920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYN22_RS10925	COG2878	Part of a membrane complex involved in electron transport
FYN22_RS10930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYN22_RS10955	COG0768	penicillin binding
FYN22_RS10960	COG0742	ribosomal rna small subunit methyltransferase
FYN22_RS10990	COG3119	arylsulfatase activity
FYN22_RS11015	COG1597	lipid kinase activity
FYN22_RS11035	COG0477	Major facilitator Superfamily
FYN22_RS11075	COG3321	synthase
FYN22_RS11075	COG4221	oxidoreductase activity
FYN22_RS11075	COG0604	alcohol dehydrogenase
FYN22_RS11075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYN22_RS11090	COG1695	Transcriptional regulator
FYN22_RS11135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYN22_RS11140	COG1773	rubredoxin
FYN22_RS11145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_RS11155	COG0583	DNA-binding transcription factor activity
FYN22_RS11175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYN22_RS11180	COG4181	ATPase activity
FYN22_RS11205	COG4771	TonB-dependent receptor
FYN22_RS11225	COG0306	phosphate transporter
FYN22_RS11240	COG2852	Protein conserved in bacteria
FYN22_RS11255	COG2223	nitrite transmembrane transporter activity
FYN22_RS11260	COG2207	Transcriptional regulator
FYN22_RS11265	COG0242	peptide deformylase activity
FYN22_RS11270	COG0477	Major facilitator Superfamily
FYN22_RS11315	COG2199	diguanylate cyclase activity
FYN22_RS11315	COG2203	Gaf domain
FYN22_RS11325	COG4681	YaeQ
FYN22_RS11330	COG0523	cobalamin synthesis protein
FYN22_RS11340	COG1607	acyl-coa hydrolase
FYN22_RS11345	COG1752	Esterase of the alpha-beta hydrolase superfamily
FYN22_RS11355	COG1115	amino acid carrier protein
FYN22_RS11360	COG0786	glutamate:sodium symporter activity
FYN22_RS11375	COG2814	Major facilitator Superfamily
FYN22_RS11380	COG1289	transmembrane transporter activity
FYN22_RS11390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FYN22_RS11460	COG2832	Protein of unknown function (DUF454)
FYN22_RS11470	COG5510	response to toxic substance
FYN22_RS11475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYN22_RS11485	COG0643	Histidine kinase
FYN22_RS11485	COG2198	Histidine kinase
FYN22_RS11485	COG0784	Response regulator, receiver
FYN22_RS11490	COG0840	transmembrane signaling receptor activity
FYN22_RS11560	COG2358	TRAP transporter, solute receptor (TAXI family
FYN22_RS11575	COG0489	protein tyrosine kinase activity
FYN22_RS11600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYN22_RS11600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYN22_RS11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_RS11635	COG4716	Myosin-crossreactive antigen
FYN22_RS11665	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FYN22_RS11670	COG2081	HI0933 family
FYN22_RS11680	COG0668	transmembrane transport
FYN22_RS11700	COG0765	amino acid transport
FYN22_RS11705	COG0765	amino acid transport
FYN22_RS11710	COG1126	abc transporter atp-binding protein
FYN22_RS11720	COG0004	ammonium transporteR
FYN22_RS11735	COG0642	Histidine kinase
FYN22_RS11740	COG0745	RESPONSE REGULATOR receiver
FYN22_RS11765	COG1752	Esterase of the alpha-beta hydrolase superfamily
FYN22_RS11780	COG0142	geranyltranstransferase activity
FYN22_RS11785	COG2828	Protein conserved in bacteria
FYN22_RS11790	COG1113	amino acid transport
FYN22_RS11805	COG1113	amino acid transport
FYN22_RS11825	COG0625	glutathione transferase activity
FYN22_RS11840	COG0431	NADPH-dependent FMN reductase
FYN22_RS11845	COG0798	PFAM Bile acid sodium symporter
FYN22_RS11855	COG0640	Transcriptional regulator
FYN22_RS11905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYN22_RS11915	COG0424	maF-like protein
FYN22_RS11920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FYN22_RS11925	COG1792	Involved in formation and maintenance of cell shape
FYN22_RS11930	COG1077	Cell shape determining protein MreB Mrl
FYN22_RS11935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYN22_RS11945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYN22_RS11980	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FYN22_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS11995	COG2610	gluconate transmembrane transporter activity
FYN22_RS12000	COG0583	DNA-binding transcription factor activity
FYN22_RS12010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_RS12020	COG4772	TonB-dependent receptor
FYN22_RS12025	COG4993	Dehydrogenase
FYN22_RS12030	COG3659	wide pore channel activity
FYN22_RS12035	COG3420	alginic acid biosynthetic process
FYN22_RS12040	COG0710	3-dehydroquinate dehydratase activity
FYN22_RS12045	COG3485	protocatechuate 3,4-dioxygenase
FYN22_RS12050	COG3485	protocatechuate 3,4-dioxygenase
FYN22_RS12055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYN22_RS12060	COG2271	Major facilitator Superfamily
FYN22_RS12065	COG0596	Alpha beta hydrolase
FYN22_RS12070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYN22_RS12075	COG0183	Belongs to the thiolase family
FYN22_RS12080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_RS12085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FYN22_RS12090	COG1414	Transcriptional regulator
FYN22_RS12120	COG1113	amino acid transport
FYN22_RS12130	COG3724	N-succinylarginine dihydrolase activity
FYN22_RS12135	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_RS12140	COG3138	arginine N-succinyltransferase
FYN22_RS12150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYN22_RS12155	COG1522	sequence-specific DNA binding
FYN22_RS12175	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_RS12180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYN22_RS12190	COG1113	amino acid transport
FYN22_RS12205	COG1271	oxidase subunit
FYN22_RS12210	COG1294	oxidase, subunit
FYN22_RS12220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYN22_RS12230	COG1346	cytolysis
FYN22_RS12240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_RS12250	COG1522	sequence-specific DNA binding
FYN22_RS12275	COG2963	transposase activity
FYN22_RS12285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYN22_RS12305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FYN22_RS12310	COG0583	DNA-binding transcription factor activity
FYN22_RS12315	COG4221	oxidoreductase activity
FYN22_RS12345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FYN22_RS12380	COG0642	Histidine kinase
FYN22_RS12395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYN22_RS12420	COG2816	NAD+ diphosphatase activity
FYN22_RS12425	COG3046	protein related to deoxyribodipyrimidine photolyase
FYN22_RS12470	COG3177	Filamentation induced by cAMP protein fic
FYN22_RS12475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FYN22_RS12535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FYN22_RS12600	COG0582	viral genome integration into host DNA
FYN22_RS12610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYN22_RS12615	COG2814	Major facilitator Superfamily
FYN22_RS12620	COG1566	PFAM secretion protein HlyD family protein
FYN22_RS12625	COG2050	protein possibly involved in aromatic compounds catabolism
FYN22_RS12640	COG1090	epimerase
FYN22_RS12650	COG5001	Diguanylate cyclase
FYN22_RS12650	COG4251	negative regulation of phosphorylation
FYN22_RS12650	COG2203	Gaf domain
FYN22_RS12650	COG3706	GGDEF domain
FYN22_RS12655	COG0420	3'-5' exonuclease activity
FYN22_RS12685	COG0735	belongs to the Fur family
FYN22_RS12690	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYN22_RS12695	COG2914	Belongs to the UPF0125 (RnfH) family
FYN22_RS12710	COG0121	glutamine amidotransferase
FYN22_RS12725	COG0756	dUTP diphosphatase activity
FYN22_RS12730	COG0210	DNA helicase
FYN22_RS12735	COG2885	chlorophyll binding
FYN22_RS12740	COG0204	Acyl-transferase
FYN22_RS12750	COG0850	regulation of cytokinetic process
FYN22_RS12755	COG2894	cell division
FYN22_RS12760	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYN22_RS12775	COG0531	amino acid
FYN22_RS12775	COG1674	ftsk spoiiie
FYN22_RS12780	COG0492	ferredoxin-NADP+ reductase activity
FYN22_RS12785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYN22_RS12795	COG0456	acetyltransferase
FYN22_RS12840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYN22_RS12855	COG1981	membrane
FYN22_RS12865	COG1113	amino acid transport
FYN22_RS12870	COG0251	oxidation-reduction process
FYN22_RS12900	COG0351	phosphomethylpyrimidine kinase
FYN22_RS12900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FYN22_RS12900	COG0352	thiamine-phosphate diphosphorylase activity
FYN22_RS12910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYN22_RS12935	COG2132	Multicopper oxidase
FYN22_RS12945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYN22_RS12980	COG1968	undecaprenyl-diphosphatase activity
FYN22_RS12985	COG1214	PFAM Peptidase M22, glycoprotease
FYN22_RS12990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FYN22_RS12995	COG0494	nUDIX hydrolase
FYN22_RS13045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYN22_RS13055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYN22_RS13080	COG0693	protein deglycase activity
FYN22_RS13100	COG2814	Major facilitator Superfamily
FYN22_RS13130	COG2853	Lipoprotein
FYN22_RS13135	COG2208	phosphoserine phosphatase activity
FYN22_RS13145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYN22_RS13150	COG1764	response to oxidative stress
FYN22_RS13180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYN22_RS13180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYN22_RS13195	COG0037	tRNA processing
FYN22_RS13205	COG0248	Ppx GppA phosphatase
FYN22_RS13230	COG0072	phenylalanine-tRNA ligase activity
FYN22_RS13275	COG1238	metal cluster binding
FYN22_RS13285	COG0625	glutathione transferase activity
FYN22_RS13305	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_RS13310	COG3028	Belongs to the UPF0307 family
FYN22_RS13320	COG1660	Displays ATPase and GTPase activities
FYN22_RS13325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYN22_RS13335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FYN22_RS13340	COG0617	tRNA 3'-terminal CCA addition
FYN22_RS13345	COG1555	photosystem II stabilization
FYN22_RS13350	COG3956	TIGRFAM MazG family protein
FYN22_RS13360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYN22_RS13375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYN22_RS13380	COG0784	Response regulator, receiver
FYN22_RS13380	COG5002	protein histidine kinase activity
FYN22_RS13380	COG2205	protein histidine kinase activity
FYN22_RS13385	COG1024	Enoyl-CoA hydratase
FYN22_RS13390	COG2084	Dehydrogenase
FYN22_RS13395	COG3622	Belongs to the hyi family
FYN22_RS13410	COG0004	ammonium transporteR
FYN22_RS13440	COG2814	Major facilitator Superfamily
FYN22_RS13455	COG2072	flavoprotein involved in K transport
FYN22_RS13460	COG0492	ferredoxin-NADP+ reductase activity
FYN22_RS13465	COG0431	NADPH-dependent FMN reductase
FYN22_RS13470	COG0798	PFAM Bile acid sodium symporter
FYN22_RS13480	COG0640	Transcriptional regulator
FYN22_RS13560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYN22_RS13580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYN22_RS13635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYN22_RS13645	COG0084	hydrolase, TatD family'
FYN22_RS13660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYN22_RS13670	COG0793	Belongs to the peptidase S41A family
FYN22_RS13690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYN22_RS13695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYN22_RS13700	COG0857	belongs to the CobB CobQ family
FYN22_RS13700	COG0280	phosphate acetyltransferase
FYN22_RS13725	COG2207	Transcriptional regulator
FYN22_RS13725	COG3708	Transcriptional regulator
FYN22_RS13735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FYN22_RS13735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FYN22_RS13755	COG0740	serine-type endopeptidase activity
FYN22_RS13765	COG4771	TonB-dependent receptor
FYN22_RS13770	COG4774	siderophore transport
FYN22_RS13785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYN22_RS13795	COG2813	Specifically methylates the guanine in position
FYN22_RS13795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYN22_RS13905	COG0788	formyltetrahydrofolate deformylase activity
FYN22_RS13930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYN22_RS13930	COG4651	solute:proton antiporter activity
FYN22_RS13955	COG0210	DNA helicase
FYN22_RS13960	COG1929	Belongs to the glycerate kinase type-1 family
FYN22_RS14000	COG2900	Belongs to the SlyX family
FYN22_RS14005	COG0488	(ABC) transporter
FYN22_RS14015	COG1560	Kdo2-lipid A biosynthetic process
FYN22_RS14075	COG0473	3-isopropylmalate dehydrogenase activity
FYN22_RS14090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYN22_RS14100	COG0583	DNA-binding transcription factor activity
FYN22_RS14135	COG1280	lysine exporter protein (LysE YggA)
FYN22_RS14150	COG1960	acyl-CoA dehydrogenase activity
FYN22_RS14160	COG3293	Transposase
FYN22_RS14200	COG0583	DNA-binding transcription factor activity
FYN22_RS14215	COG0564	pseudouridine synthase activity
FYN22_RS14225	COG1530	ribonuclease E activity
FYN22_RS14230	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_RS14255	COG1983	PspC domain protein
FYN22_RS14275	COG0751	glycine-tRNA ligase activity
FYN22_RS14310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYN22_RS14325	COG2226	methyltransferase
FYN22_RS14340	COG0493	'glutamate synthase
FYN22_RS14340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYN22_RS14350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FYN22_RS14360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_RS14365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYN22_RS14375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FYN22_RS14385	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FYN22_RS14385	COG0644	oxidoreductase
FYN22_RS14395	COG0425	Belongs to the sulfur carrier protein TusA family
FYN22_RS14400	COG4535	Mg2 and Co2 transporter CorC
FYN22_RS14405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYN22_RS14410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYN22_RS14430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYN22_RS14440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYN22_RS14460	COG2841	Protein conserved in bacteria
FYN22_RS14465	COG0598	Magnesium transport protein CorA
FYN22_RS14470	COG1185	polyribonucleotide nucleotidyltransferase activity
FYN22_RS14480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FYN22_RS14485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYN22_RS14490	COG1074	ATP-dependent DNA helicase activity
FYN22_RS14495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FYN22_RS14525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYN22_RS14540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYN22_RS14550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FYN22_RS14555	COG2111	Na H antiporter
FYN22_RS14555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYN22_RS14560	COG1006	Multisubunit Na H antiporter MnhC subunit
FYN22_RS14565	COG0651	ATP synthesis coupled electron transport
FYN22_RS14570	COG1863	multisubunit Na H antiporter MnhE subunit
FYN22_RS14575	COG2212	antiporter activity
FYN22_RS14580	COG1320	monovalent cation:proton antiporter activity
FYN22_RS14585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYN22_RS14595	COG0195	Participates in both transcription termination and antitermination
FYN22_RS14655	COG0237	dephospho-CoA kinase activity
FYN22_RS14665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYN22_RS14675	COG0497	DNA recombination
FYN22_RS14680	COG1678	Uncharacterized ACR, COG1678
FYN22_RS14685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYN22_RS14700	COG1289	transmembrane transporter activity
FYN22_RS14715	COG1132	(ABC) transporter
FYN22_RS14720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYN22_RS14790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FYN22_RS14815	COG0326	Molecular chaperone. Has ATPase activity
FYN22_RS14825	COG3047	cAMP biosynthetic process
FYN22_RS14830	COG2056	Na+-H+ antiporter family
FYN22_RS14855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYN22_RS14860	COG0085	RNA polymerase activity
FYN22_RS14865	COG0222	ribosome binding
FYN22_RS14870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYN22_RS14875	COG0081	regulation of translation
FYN22_RS14880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYN22_RS14930	COG0546	phosphoglycolate phosphatase activity
FYN22_RS14965	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_RS14995	COG1324	tolerance protein
FYN22_RS15000	COG0673	inositol 2-dehydrogenase activity
FYN22_RS15020	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_RS15025	COG0824	Thioesterase
FYN22_RS15045	COG0181	hydroxymethylbilane synthase activity
FYN22_RS15055	COG3275	phosphorelay sensor kinase activity
FYN22_RS15075	COG1538	Outer membrane efflux protein
FYN22_RS15085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYN22_RS15095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYN22_RS15100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FYN22_RS15105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYN22_RS15110	COG0772	Belongs to the SEDS family
FYN22_RS15115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYN22_RS15135	COG4974	Belongs to the 'phage' integrase family
FYN22_RS15140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYN22_RS15150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FYN22_RS15155	COG1686	Belongs to the peptidase S11 family
FYN22_RS15160	COG2197	response regulator
FYN22_RS15175	COG0793	Belongs to the peptidase S41A family
FYN22_RS15180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FYN22_RS15185	COG0795	lipopolysaccharide-transporting ATPase activity
FYN22_RS15190	COG0795	lipopolysaccharide-transporting ATPase activity
FYN22_RS15210	COG0586	Pfam SNARE associated Golgi protein
FYN22_RS15225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYN22_RS15225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYN22_RS15235	COG0004	ammonium transporteR
FYN22_RS15240	COG0347	Belongs to the P(II) protein family
FYN22_RS15250	COG0606	chelatase, subunit chli
FYN22_RS15270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FYN22_RS15285	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_RS15295	COG0477	Major facilitator Superfamily
FYN22_RS15300	COG2860	membrane
FYN22_RS15305	COG3012	SEC-C Motif Domain Protein
FYN22_RS15310	COG1253	flavin adenine dinucleotide binding
FYN22_RS15330	COG2814	Major facilitator Superfamily
FYN22_RS15340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_RS15420	COG0758	DNA mediated transformation
FYN22_RS15430	COG0697	spore germination
FYN22_RS15440	COG0386	Belongs to the glutathione peroxidase family
FYN22_RS15475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYN22_RS15525	COG1121	(ABC) transporter
FYN22_RS15530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYN22_RS15545	COG2837	iron assimilation
FYN22_RS15555	COG1388	LysM domain
FYN22_RS15555	COG5632	N-Acetylmuramoyl-L-alanine amidase
FYN22_RS15555	COG3409	Peptidoglycan-binding domain 1 protein
FYN22_RS15565	COG0281	malic enzyme
FYN22_RS15615	COG0519	Catalyzes the synthesis of GMP from XMP
FYN22_RS15615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYN22_RS15630	COG0586	Pfam SNARE associated Golgi protein
FYN22_RS15645	COG1192	Involved in chromosome partitioning
FYN22_RS15655	COG0271	Belongs to the BolA IbaG family
FYN22_RS15750	COG1538	Outer membrane efflux protein
FYN22_RS15950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYN22_RS15955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FYN22_RS15955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYN22_RS15955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYN22_RS15960	COG1105	Belongs to the carbohydrate kinase PfkB family
FYN22_RS15965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYN22_RS15965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYN22_RS15970	COG0583	DNA-binding transcription factor activity
FYN22_RS15975	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYN22_RS15990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYN22_RS16000	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FYN22_RS16005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYN22_RS16015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FYN22_RS16020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYN22_RS16025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FYN22_RS16040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FYN22_RS16055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYN22_RS16070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FYN22_RS16080	COG1086	Polysaccharide biosynthesis protein
FYN22_RS16095	COG0438	transferase activity, transferring glycosyl groups
FYN22_RS16105	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYN22_RS16115	COG1596	polysaccharide export
FYN22_RS16140	COG0728	peptidoglycan biosynthetic process
FYN22_RS16145	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYN22_RS16155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYN22_RS16165	COG3307	-O-antigen
FYN22_RS16170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYN22_RS16175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYN22_RS16180	COG0546	phosphoglycolate phosphatase activity
FYN22_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_RS16205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYN22_RS16205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYN22_RS16210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_RS16215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_RS16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYN22_RS16225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYN22_RS16230	COG1116	anion transmembrane transporter activity
FYN22_RS16235	COG1309	transcriptional regulator
FYN22_RS16250	COG0196	riboflavin kinase activity
FYN22_RS16255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYN22_RS16260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYN22_RS16265	COG1047	Peptidyl-prolyl cis-trans
FYN22_RS16280	COG2133	pyrroloquinoline quinone binding
FYN22_RS16310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYN22_RS16315	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYN22_RS16320	COG2951	lytic endotransglycosylase activity
FYN22_RS16325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYN22_RS16340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYN22_RS16360	COG0861	Integral membrane protein TerC family
FYN22_RS16370	COG0754	glutathionylspermidine amidase activity
FYN22_RS16380	COG0402	S-adenosylhomocysteine deaminase activity
FYN22_RS16400	COG1230	cation diffusion facilitator family transporter
FYN22_RS16420	COG0706	membrane insertase activity
FYN22_RS16425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYN22_RS16535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYN22_RS16560	COG0789	Transcriptional regulator
FYN22_RS16635	COG0210	DNA helicase
FYN22_RS16655	COG0583	DNA-binding transcription factor activity
FYN22_RS16660	COG2814	Major facilitator Superfamily
FYN22_RS16690	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_RS16730	COG1538	Outer membrane efflux protein
FYN22_RS16735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYN22_RS16745	COG0745	RESPONSE REGULATOR receiver
FYN22_RS16750	COG2205	protein histidine kinase activity
FYN22_RS16765	COG3173	Aminoglycoside phosphotransferase
FYN22_RS16770	COG0488	(ABC) transporter
FYN22_RS16790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYN22_RS16795	COG3657	addiction module killer protein
FYN22_RS16890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYN22_RS16910	COG4372	Transposase
FYN22_RS17225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_RS17230	COG1230	cation diffusion facilitator family transporter
FYN22_RS17240	COG0640	Transcriptional regulator
FYN22_RS17250	COG0789	Transcriptional regulator
FYN22_RS17360	COG1192	Involved in chromosome partitioning
FYN22_RS17365	COG1475	DNA binding
FYN22_RS17545	COG2009	succinate dehydrogenase
FYN22_RS17565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYN22_RS17575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYN22_RS17630	COG0625	glutathione transferase activity
FYN22_RS17635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_RS17660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_RS17695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_RS17760	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_RS17770	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_RS17930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYN22_RS17985	COG1525	nuclease
FYN22_RS18025	COG4977	sequence-specific DNA binding
FYN22_RS18025	COG1917	Cupin 2, conserved barrel domain protein
FYN22_RS18030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_RS18040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYN22_RS18045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_RS18060	COG0183	Belongs to the thiolase family
FYN22_RS18065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_RS18135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FYN22_RS18155	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FYN22_RS18160	COG3421	Type III restriction
FYN22_RS18200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FYN22_RS18315	COG4115	mRNA cleavage
FYN22_RS18360	COG4115	mRNA cleavage
FYN22_RS18405	COG4115	mRNA cleavage