locus-tag	class	description
CFH90_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFH90_RS00010	COG0592	DNA-directed DNA polymerase activity
CFH90_RS00020	COG0187	DNA topoisomerase II activity
CFH90_RS00035	COG0488	(ABC) transporter
CFH90_RS00095	COG0657	acetylesterase activity
CFH90_RS00115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFH90_RS00145	COG2814	Major facilitator Superfamily
CFH90_RS00155	COG2801	Transposase and inactivated derivatives
CFH90_RS00160	COG0733	neurotransmitter:sodium symporter activity
CFH90_RS00185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFH90_RS00185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFH90_RS00200	COG0129	dihydroxy-acid dehydratase activity
CFH90_RS00210	COG4774	siderophore transport
CFH90_RS00220	COG0583	DNA-binding transcription factor activity
CFH90_RS00225	COG2233	PERMEase
CFH90_RS00235	COG1309	transcriptional regulator
CFH90_RS00260	COG0484	heat shock protein binding
CFH90_RS00270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFH90_RS00290	COG1064	alcohol dehydrogenase
CFH90_RS00295	COG2818	Glycosylase
CFH90_RS00325	COG5487	UPF0391 membrane protein
CFH90_RS00330	COG2983	Belongs to the UPF0260 family
CFH90_RS00335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFH90_RS00365	COG4160	amino acid transport
CFH90_RS00370	COG4215	(ABC) transporter
CFH90_RS00375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFH90_RS00395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFH90_RS00405	COG1335	isochorismatase
CFH90_RS00410	COG0385	Bile acid
CFH90_RS00480	COG0534	Mate efflux family protein
CFH90_RS00485	COG0436	Aminotransferase
CFH90_RS00490	COG2733	membrane
CFH90_RS00505	COG2918	glutathione biosynthetic process
CFH90_RS00510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CFH90_RS00520	COG3150	esterase
CFH90_RS00615	COG3706	GGDEF domain
CFH90_RS00625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFH90_RS00640	COG1393	Belongs to the ArsC family
CFH90_RS00645	COG0708	Exodeoxyribonuclease III
CFH90_RS00655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFH90_RS00670	COG1846	Transcriptional regulator
CFH90_RS00675	COG0386	Belongs to the glutathione peroxidase family
CFH90_RS00680	COG0189	ligase activity
CFH90_RS00690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFH90_RS00700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFH90_RS00710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFH90_RS00735	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFH90_RS00740	COG2119	membrane
CFH90_RS00745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_RS00745	COG0426	domain, Protein
CFH90_RS00770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFH90_RS00795	COG1902	pentaerythritol trinitrate reductase activity
CFH90_RS00800	COG1519	Transferase
CFH90_RS00805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFH90_RS00810	COG0668	transmembrane transport
CFH90_RS00815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFH90_RS00820	COG0307	riboflavin synthase, alpha
CFH90_RS00825	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS00840	COG0431	NADPH-dependent FMN reductase
CFH90_RS00855	COG2205	protein histidine kinase activity
CFH90_RS00855	COG0784	Response regulator, receiver
CFH90_RS00860	COG3162	membrane
CFH90_RS00875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFH90_RS00915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CFH90_RS00915	COG0351	phosphomethylpyrimidine kinase
CFH90_RS00915	COG0352	thiamine-phosphate diphosphorylase activity
CFH90_RS00925	COG2814	Major facilitator Superfamily
CFH90_RS00930	COG0629	single-stranded DNA binding
CFH90_RS00950	COG4372	Transposase
CFH90_RS00955	COG0583	DNA-binding transcription factor activity
CFH90_RS00980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_RS01010	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CFH90_RS01135	COG0582	viral genome integration into host DNA
CFH90_RS01145	COG3158	transport of potassium into the cell
CFH90_RS01260	COG1840	ABC-type Fe3 transport system, periplasmic component
CFH90_RS01265	COG3842	ATPase activity
CFH90_RS01305	COG2801	Transposase and inactivated derivatives
CFH90_RS01345	COG3077	Addiction module antitoxin, RelB DinJ family
CFH90_RS01350	COG3706	GGDEF domain
CFH90_RS01355	COG0753	catalase activity
CFH90_RS01360	COG2801	Transposase and inactivated derivatives
CFH90_RS01380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFH90_RS01385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_RS01430	COG2814	Major facilitator Superfamily
CFH90_RS01510	COG2217	Heavy metal translocating P-type atpase
CFH90_RS01515	COG3174	membrane
CFH90_RS01520	COG2205	protein histidine kinase activity
CFH90_RS01535	COG2132	Multicopper oxidase
CFH90_RS01570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFH90_RS01595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFH90_RS01600	COG1278	Cold shock
CFH90_RS01635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFH90_RS01670	COG0427	acetyl-CoA hydrolase
CFH90_RS01700	COG4221	oxidoreductase activity
CFH90_RS01705	COG2873	o-acetylhomoserine
CFH90_RS01710	COG0488	(ABC) transporter
CFH90_RS01730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFH90_RS01775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFH90_RS01780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFH90_RS01790	COG2226	methyltransferase
CFH90_RS01840	COG0070	glutamate synthase
CFH90_RS01840	COG0069	glutamate synthase activity
CFH90_RS01840	COG0067	glutamate synthase
CFH90_RS01845	COG0493	'glutamate synthase
CFH90_RS01855	COG1704	LemA family
CFH90_RS01860	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CFH90_RS01945	COG4969	Belongs to the N-Me-Phe pilin family
CFH90_RS01985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFH90_RS01990	COG1758	RNA polymerase activity
CFH90_RS01995	COG0194	GDP metabolic process
CFH90_RS02045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFH90_RS02055	COG0335	large ribosomal subunit rRNA binding
CFH90_RS02070	COG5380	lipid catabolic process
CFH90_RS02075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFH90_RS02095	COG5006	permease, DMT superfamily
CFH90_RS02100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFH90_RS02105	COG0277	FAD linked oxidase domain protein
CFH90_RS02130	COG3335	DDE superfamily endonuclease
CFH90_RS02140	COG2814	Major facilitator Superfamily
CFH90_RS02145	COG1289	transmembrane transporter activity
CFH90_RS02150	COG2032	superoxide dismutase activity
CFH90_RS02155	COG0628	permease
CFH90_RS02160	COG1192	Involved in chromosome partitioning
CFH90_RS02170	COG2226	methyltransferase
CFH90_RS02185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFH90_RS02190	COG0254	rRNA binding
CFH90_RS02195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFH90_RS02205	COG0534	Mate efflux family protein
CFH90_RS02215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFH90_RS02235	COG1910	domain protein
CFH90_RS02240	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS02260	COG0408	coproporphyrinogen oxidase activity
CFH90_RS02265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFH90_RS02285	COG0513	Belongs to the DEAD box helicase family
CFH90_RS02290	COG1127	ABC transporter
CFH90_RS02295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFH90_RS02300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFH90_RS02305	COG2854	intermembrane phospholipid transfer
CFH90_RS02315	COG0598	Magnesium transport protein CorA
CFH90_RS02325	COG0494	nUDIX hydrolase
CFH90_RS02330	COG1040	competence protein
CFH90_RS02335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFH90_RS02360	COG2937	Belongs to the GPAT DAPAT family
CFH90_RS02365	COG1946	Acyl-CoA thioesterase
CFH90_RS02370	COG1301	dicarboxylic acid transport
CFH90_RS02385	COG1959	2 iron, 2 sulfur cluster binding
CFH90_RS02395	COG0433	COG0433 Predicted ATPase
CFH90_RS02415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFH90_RS02420	COG0088	Forms part of the polypeptide exit tunnel
CFH90_RS02435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFH90_RS02485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFH90_RS02490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFH90_RS02500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFH90_RS02525	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFH90_RS02540	COG0202	RNA polymerase activity
CFH90_RS02545	COG0203	ribosomal protein L17
CFH90_RS02550	COG2072	flavoprotein involved in K transport
CFH90_RS02560	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS02565	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CFH90_RS02595	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CFH90_RS02600	COG0339	signal peptide processing
CFH90_RS02605	COG2720	vancomycin resistance protein
CFH90_RS02610	COG0557	exoribonuclease II activity
CFH90_RS02645	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFH90_RS02660	COG1295	ribonuclease BN
CFH90_RS02710	COG4773	Receptor
CFH90_RS02720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFH90_RS02725	COG1702	phosphate starvation-inducible protein PhoH
CFH90_RS02730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFH90_RS02735	COG0741	lytic transglycosylase activity
CFH90_RS02735	COG0739	heme binding
CFH90_RS02735	COG1196	nuclear chromosome segregation
CFH90_RS02745	COG0039	L-malate dehydrogenase activity
CFH90_RS02770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFH90_RS02775	COG1183	phosphatidylcholine synthase activity
CFH90_RS02835	COG1607	acyl-coa hydrolase
CFH90_RS02850	COG1666	GTP binding
CFH90_RS02870	COG2350	Protein conserved in bacteria
CFH90_RS02880	COG0613	PHP domain protein
CFH90_RS02885	COG3781	membrane
CFH90_RS02895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFH90_RS02920	COG1162	GTPase activity
CFH90_RS02925	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CFH90_RS02955	COG1136	(ABC) transporter
CFH90_RS02955	COG0577	efflux transmembrane transporter activity
CFH90_RS02960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_RS02985	COG0028	Belongs to the TPP enzyme family
CFH90_RS02990	COG0440	acetolactate synthase activity
CFH90_RS03060	COG1426	Protein conserved in bacteria
CFH90_RS03080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFH90_RS03105	COG1862	Preprotein translocase
CFH90_RS03115	COG1704	LemA family
CFH90_RS03125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFH90_RS03140	COG5002	protein histidine kinase activity
CFH90_RS03145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFH90_RS03215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFH90_RS03245	COG3223	Belongs to the PsiE family
CFH90_RS03260	COG4969	Belongs to the N-Me-Phe pilin family
CFH90_RS03280	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS03285	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS03295	COG2205	protein histidine kinase activity
CFH90_RS03300	COG0745	RESPONSE REGULATOR receiver
CFH90_RS03305	COG1113	amino acid transport
CFH90_RS03310	COG2315	Protein conserved in bacteria
CFH90_RS03315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFH90_RS03335	COG2096	Adenosyltransferase
CFH90_RS03340	COG4206	TonB-dependent receptor
CFH90_RS03365	COG3083	sulfuric ester hydrolase activity
CFH90_RS03395	COG0285	dihydrofolate synthase activity
CFH90_RS03415	COG0450	alkyl hydroperoxide reductase
CFH90_RS03435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFH90_RS03440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFH90_RS03470	COG2199	diguanylate cyclase activity
CFH90_RS03505	COG2814	Major facilitator Superfamily
CFH90_RS03530	COG0693	protein deglycase activity
CFH90_RS03570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFH90_RS03580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFH90_RS03640	COG0494	nUDIX hydrolase
CFH90_RS03645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFH90_RS03650	COG1214	PFAM Peptidase M22, glycoprotease
CFH90_RS03655	COG1968	undecaprenyl-diphosphatase activity
CFH90_RS03690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFH90_RS03735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFH90_RS03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFH90_RS03775	COG0251	oxidation-reduction process
CFH90_RS03780	COG1113	amino acid transport
CFH90_RS03790	COG1981	membrane
CFH90_RS03805	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFH90_RS03820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFH90_RS03830	COG0456	acetyltransferase
CFH90_RS03840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFH90_RS03845	COG0492	ferredoxin-NADP+ reductase activity
CFH90_RS03850	COG1674	ftsk spoiiie
CFH90_RS03850	COG0531	amino acid
CFH90_RS03865	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFH90_RS03870	COG2894	cell division
CFH90_RS03875	COG0850	regulation of cytokinetic process
CFH90_RS03885	COG0204	Acyl-transferase
CFH90_RS03890	COG2885	chlorophyll binding
CFH90_RS03895	COG0210	DNA helicase
CFH90_RS03900	COG0756	dUTP diphosphatase activity
CFH90_RS03915	COG0121	glutamine amidotransferase
CFH90_RS03930	COG2914	Belongs to the UPF0125 (RnfH) family
CFH90_RS03935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFH90_RS03940	COG0735	belongs to the Fur family
CFH90_RS03970	COG0420	3'-5' exonuclease activity
CFH90_RS03975	COG2203	Gaf domain
CFH90_RS03975	COG3706	GGDEF domain
CFH90_RS03975	COG5001	Diguanylate cyclase
CFH90_RS03975	COG4251	negative regulation of phosphorylation
CFH90_RS03985	COG1090	epimerase
CFH90_RS04000	COG2050	protein possibly involved in aromatic compounds catabolism
CFH90_RS04005	COG1566	PFAM secretion protein HlyD family protein
CFH90_RS04010	COG2814	Major facilitator Superfamily
CFH90_RS04015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFH90_RS04025	COG0582	viral genome integration into host DNA
CFH90_RS04045	COG3617	BRO family, N-terminal domain
CFH90_RS04105	COG0582	viral genome integration into host DNA
CFH90_RS04180	COG3177	Filamentation induced by cAMP protein fic
CFH90_RS04215	COG4221	oxidoreductase activity
CFH90_RS04220	COG0583	DNA-binding transcription factor activity
CFH90_RS04225	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFH90_RS04230	COG3321	synthase
CFH90_RS04230	COG0604	alcohol dehydrogenase
CFH90_RS04245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFH90_RS04255	COG1979	alcohol dehydrogenase
CFH90_RS04265	COG1902	pentaerythritol trinitrate reductase activity
CFH90_RS04275	COG1309	transcriptional regulator
CFH90_RS04280	COG2130	NADP-dependent
CFH90_RS04310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_RS04320	COG1346	cytolysis
CFH90_RS04330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFH90_RS04340	COG1294	oxidase, subunit
CFH90_RS04345	COG1271	oxidase subunit
CFH90_RS04360	COG1113	amino acid transport
CFH90_RS04370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFH90_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
CFH90_RS04390	COG3138	arginine N-succinyltransferase
CFH90_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
CFH90_RS04400	COG3724	N-succinylarginine dihydrolase activity
CFH90_RS04410	COG1113	amino acid transport
CFH90_RS04420	COG1414	Transcriptional regulator
CFH90_RS04425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFH90_RS04430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_RS04435	COG0183	Belongs to the thiolase family
CFH90_RS04440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFH90_RS04445	COG0596	Alpha beta hydrolase
CFH90_RS04450	COG2271	Major facilitator Superfamily
CFH90_RS04455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFH90_RS04460	COG3485	protocatechuate 3,4-dioxygenase
CFH90_RS04465	COG3485	protocatechuate 3,4-dioxygenase
CFH90_RS04470	COG0710	3-dehydroquinate dehydratase activity
CFH90_RS04475	COG3420	alginic acid biosynthetic process
CFH90_RS04480	COG3659	wide pore channel activity
CFH90_RS04485	COG4993	Dehydrogenase
CFH90_RS04490	COG4772	TonB-dependent receptor
CFH90_RS04500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_RS04510	COG0583	DNA-binding transcription factor activity
CFH90_RS04515	COG2610	gluconate transmembrane transporter activity
CFH90_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS04535	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFH90_RS04565	COG2801	Transposase and inactivated derivatives
CFH90_RS04580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFH90_RS04590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFH90_RS04595	COG1077	Cell shape determining protein MreB Mrl
CFH90_RS04600	COG1792	Involved in formation and maintenance of cell shape
CFH90_RS04605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CFH90_RS04610	COG0424	maF-like protein
CFH90_RS04620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFH90_RS04675	COG0640	Transcriptional regulator
CFH90_RS04685	COG0798	PFAM Bile acid sodium symporter
CFH90_RS04690	COG0431	NADPH-dependent FMN reductase
CFH90_RS04705	COG0625	glutathione transferase activity
CFH90_RS04725	COG1113	amino acid transport
CFH90_RS04750	COG1113	amino acid transport
CFH90_RS04755	COG2828	Protein conserved in bacteria
CFH90_RS04760	COG0142	geranyltranstransferase activity
CFH90_RS04775	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFH90_RS04795	COG2194	sulfuric ester hydrolase activity
CFH90_RS04800	COG0745	RESPONSE REGULATOR receiver
CFH90_RS04805	COG0642	Histidine kinase
CFH90_RS04820	COG0004	ammonium transporteR
CFH90_RS04830	COG1126	abc transporter atp-binding protein
CFH90_RS04835	COG0765	amino acid transport
CFH90_RS04840	COG0765	amino acid transport
CFH90_RS04860	COG0668	transmembrane transport
CFH90_RS04870	COG2081	HI0933 family
CFH90_RS04875	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CFH90_RS04905	COG4716	Myosin-crossreactive antigen
CFH90_RS04930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_RS04940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFH90_RS04940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFH90_RS04960	COG0489	protein tyrosine kinase activity
CFH90_RS04975	COG2358	TRAP transporter, solute receptor (TAXI family
CFH90_RS05045	COG0840	transmembrane signaling receptor activity
CFH90_RS05050	COG0784	Response regulator, receiver
CFH90_RS05050	COG2198	Histidine kinase
CFH90_RS05050	COG0643	Histidine kinase
CFH90_RS05060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFH90_RS05065	COG5510	response to toxic substance
CFH90_RS05075	COG2832	Protein of unknown function (DUF454)
CFH90_RS05085	COG3293	Transposase
CFH90_RS05150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFH90_RS05160	COG1289	transmembrane transporter activity
CFH90_RS05165	COG2814	Major facilitator Superfamily
CFH90_RS05180	COG0786	glutamate:sodium symporter activity
CFH90_RS05185	COG1115	amino acid carrier protein
CFH90_RS05195	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFH90_RS05205	COG1607	acyl-coa hydrolase
CFH90_RS05215	COG0523	cobalamin synthesis protein
CFH90_RS05220	COG4681	YaeQ
CFH90_RS05230	COG2203	Gaf domain
CFH90_RS05230	COG2199	diguanylate cyclase activity
CFH90_RS05285	COG0477	Major facilitator Superfamily
CFH90_RS05290	COG0242	peptide deformylase activity
CFH90_RS05295	COG2207	Transcriptional regulator
CFH90_RS05315	COG0306	phosphate transporter
CFH90_RS05335	COG4771	TonB-dependent receptor
CFH90_RS05360	COG4181	ATPase activity
CFH90_RS05365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CFH90_RS05385	COG0583	DNA-binding transcription factor activity
CFH90_RS05395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_RS05400	COG1773	rubredoxin
CFH90_RS05405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFH90_RS05445	COG4221	oxidoreductase activity
CFH90_RS05445	COG0604	alcohol dehydrogenase
CFH90_RS05445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFH90_RS05445	COG3321	synthase
CFH90_RS05485	COG0477	Major facilitator Superfamily
CFH90_RS05505	COG1597	lipid kinase activity
CFH90_RS05550	COG0641	radical SAM
CFH90_RS05555	COG3119	arylsulfatase activity
CFH90_RS05580	COG3335	DDE superfamily endonuclease
CFH90_RS05600	COG0742	ribosomal rna small subunit methyltransferase
CFH90_RS05605	COG0768	penicillin binding
CFH90_RS05630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFH90_RS05635	COG2878	Part of a membrane complex involved in electron transport
CFH90_RS05640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFH90_RS05650	COG3384	dioxygenase
CFH90_RS05660	COG2234	aminopeptidase activity
CFH90_RS05675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFH90_RS05685	COG2217	Heavy metal translocating P-type atpase
CFH90_RS05690	COG0583	DNA-binding transcription factor activity
CFH90_RS05695	COG1914	H( )-stimulated, divalent metal cation uptake system
CFH90_RS05715	COG4770	biotin carboxylase activity
CFH90_RS05740	COG0006	proline dipeptidase activity
CFH90_RS05750	COG2801	Transposase and inactivated derivatives
CFH90_RS05850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFH90_RS05855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFH90_RS05875	COG2915	High frequency lysogenization protein hflD homolog
CFH90_RS05895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFH90_RS05900	COG1686	Belongs to the peptidase S11 family
CFH90_RS05940	COG0753	catalase activity
CFH90_RS05955	COG4942	peptidase
CFH90_RS05955	COG1388	LysM domain
CFH90_RS05960	COG0583	DNA-binding transcription factor activity
CFH90_RS05980	COG0657	acetylesterase activity
CFH90_RS05985	COG2816	NAD+ diphosphatase activity
CFH90_RS05995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFH90_RS06000	COG0741	lytic transglycosylase activity
CFH90_RS06000	COG1388	LysM domain
CFH90_RS06005	COG4166	transmembrane transport
CFH90_RS06010	COG4174	ABC transporter (Permease)
CFH90_RS06015	COG4239	(ABC) transporter, permease
CFH90_RS06020	COG4172	Belongs to the ABC transporter superfamily
CFH90_RS06035	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CFH90_RS06060	COG0833	amino acid
CFH90_RS06100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFH90_RS06105	COG0418	dihydroorotase activity
CFH90_RS06110	COG4251	negative regulation of phosphorylation
CFH90_RS06110	COG2203	Gaf domain
CFH90_RS06110	COG5001	Diguanylate cyclase
CFH90_RS06110	COG3706	GGDEF domain
CFH90_RS06125	COG2186	Transcriptional regulator
CFH90_RS06135	COG0277	FAD linked oxidase domain protein
CFH90_RS06140	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFH90_RS06140	COG1902	pentaerythritol trinitrate reductase activity
CFH90_RS06170	COG0280	phosphate acetyltransferase
CFH90_RS06170	COG0281	malic enzyme
CFH90_RS06180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFH90_RS06185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFH90_RS06190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFH90_RS06230	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS06235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFH90_RS06240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFH90_RS06250	COG1671	Belongs to the UPF0178 family
CFH90_RS06265	COG4591	ABC-type transport system involved in lipoprotein release permease component
CFH90_RS06270	COG1136	(ABC) transporter
CFH90_RS06275	COG0658	competence protein
CFH90_RS06275	COG2333	competence protein COMEC
CFH90_RS06295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFH90_RS06300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFH90_RS06305	COG0628	permease
CFH90_RS06310	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFH90_RS06345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFH90_RS06365	COG0823	Involved in the tonB-independent uptake of proteins
CFH90_RS06385	COG0824	Thioesterase
CFH90_RS06400	COG2255	four-way junction helicase activity
CFH90_RS06405	COG0632	four-way junction helicase activity
CFH90_RS06420	COG0047	phosphoribosylformylglycinamidine synthase activity
CFH90_RS06420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFH90_RS06430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFH90_RS06430	COG3323	Protein of unknown function (DUF1653)
CFH90_RS06450	COG1024	Enoyl-CoA hydratase
CFH90_RS06455	COG1056	cytidyltransferase-related domain
CFH90_RS06455	COG1051	belongs to the nudix hydrolase family
CFH90_RS06460	COG2353	YceI-like domain
CFH90_RS06465	COG0583	DNA-binding transcription factor activity
CFH90_RS06475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFH90_RS06490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFH90_RS06495	COG0602	queuosine metabolic process
CFH90_RS06515	COG0583	DNA-binding transcription factor activity
CFH90_RS06520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFH90_RS06525	COG4208	sulfate ABC transporter
CFH90_RS06540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFH90_RS06550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFH90_RS06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFH90_RS06575	COG3385	transposase activity
CFH90_RS06590	COG0681	Belongs to the peptidase S26 family
CFH90_RS06605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFH90_RS06615	COG1381	Involved in DNA repair and RecF pathway recombination
CFH90_RS06620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFH90_RS06655	COG0436	Aminotransferase
CFH90_RS06665	COG2199	diguanylate cyclase activity
CFH90_RS06680	COG0556	nucleotide-excision repair
CFH90_RS06715	COG0702	epimerase
CFH90_RS06720	COG1733	regulation of RNA biosynthetic process
CFH90_RS06730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFH90_RS06735	COG0671	phosphoesterase, PA-phosphatase related
CFH90_RS06740	COG4772	TonB-dependent receptor
CFH90_RS06750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFH90_RS06755	COG0076	glutamate decarboxylase activity
CFH90_RS06760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFH90_RS06765	COG0573	inorganic phosphate transmembrane transporter activity
CFH90_RS06775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFH90_RS06780	COG0616	signal peptide processing
CFH90_RS06785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFH90_RS06790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFH90_RS06795	COG1067	ATP-dependent peptidase activity
CFH90_RS06815	COG0254	rRNA binding
CFH90_RS06835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFH90_RS06840	COG1966	Carbon starvation protein
CFH90_RS06845	COG2879	small protein
CFH90_RS06855	COG0714	Associated with various cellular activities
CFH90_RS06930	COG4372	Transposase
CFH90_RS06970	COG3046	protein related to deoxyribodipyrimidine photolyase
CFH90_RS06975	COG2816	NAD+ diphosphatase activity
CFH90_RS07000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFH90_RS07015	COG0642	Histidine kinase
CFH90_RS07020	COG0745	RESPONSE REGULATOR receiver
CFH90_RS07055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFH90_RS07065	COG0783	Belongs to the Dps family
CFH90_RS07115	COG1131	(ABC) transporter
CFH90_RS07120	COG0842	Transport permease protein
CFH90_RS07125	COG0842	Transport permease protein
CFH90_RS07150	COG1309	transcriptional regulator
CFH90_RS07200	COG4372	Transposase
CFH90_RS07240	COG1733	regulation of RNA biosynthetic process
CFH90_RS07285	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFH90_RS07290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFH90_RS07305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFH90_RS07315	COG0133	tryptophan synthase activity
CFH90_RS07320	COG0517	IMP dehydrogenase activity
CFH90_RS07320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFH90_RS07350	COG0612	Peptidase, M16
CFH90_RS07355	COG0552	protein localization to endoplasmic reticulum
CFH90_RS07360	COG3293	Transposase
CFH90_RS07390	COG2175	clavaminate synthase activity
CFH90_RS07395	COG3246	L-lysine catabolic process to acetate
CFH90_RS07415	COG2855	membrane
CFH90_RS07445	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS07455	COG0372	Belongs to the citrate synthase family
CFH90_RS07485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFH90_RS07490	COG0730	response to heat
CFH90_RS07515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFH90_RS07520	COG1944	ATP diphosphatase activity
CFH90_RS07525	COG2207	Transcriptional regulator
CFH90_RS07530	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFH90_RS07535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFH90_RS07565	COG2223	nitrite transmembrane transporter activity
CFH90_RS07580	COG1346	cytolysis
CFH90_RS07585	COG1380	Effector of murein hydrolase LrgA
CFH90_RS07590	COG0583	DNA-binding transcription factor activity
CFH90_RS07595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFH90_RS07625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFH90_RS07695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFH90_RS07700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFH90_RS07715	COG5001	Diguanylate cyclase
CFH90_RS07715	COG3300	MHYT domain
CFH90_RS07720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFH90_RS07730	COG2814	Major facilitator Superfamily
CFH90_RS07745	COG1132	(ABC) transporter
CFH90_RS07755	COG0668	transmembrane transport
CFH90_RS07760	COG3122	Protein conserved in bacteria
CFH90_RS07780	COG0640	Transcriptional regulator
CFH90_RS07785	COG0596	Alpha beta hydrolase
CFH90_RS07790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFH90_RS07795	COG1335	isochorismatase
CFH90_RS07800	COG0251	oxidation-reduction process
CFH90_RS07805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_RS07810	COG2233	PERMEase
CFH90_RS07820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFH90_RS07845	COG0183	Belongs to the thiolase family
CFH90_RS07850	COG0583	DNA-binding transcription factor activity
CFH90_RS07865	COG0439	Biotin carboxylase
CFH90_RS07880	COG0511	ligase activity, forming carbon-carbon bonds
CFH90_RS07890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_RS07895	COG0183	Belongs to the thiolase family
CFH90_RS07900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_RS07905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFH90_RS07910	COG3135	benzoate transporter
CFH90_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS07920	COG0633	Ferredoxin
CFH90_RS07920	COG0543	2 iron, 2 sulfur cluster binding
CFH90_RS07925	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CFH90_RS07930	COG4638	Rieske (2fe-2S)
CFH90_RS07940	COG4829	muconolactone delta-isomerase
CFH90_RS07945	COG4948	Mandelate Racemase Muconate Lactonizing
CFH90_RS07950	COG0583	DNA-binding transcription factor activity
CFH90_RS07955	COG2814	Major facilitator Superfamily
CFH90_RS08130	COG2814	Major facilitator Superfamily
CFH90_RS08155	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFH90_RS08160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFH90_RS08165	COG0022	dehydrogenase e1 component
CFH90_RS08170	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFH90_RS08175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFH90_RS08185	COG1063	alcohol dehydrogenase
CFH90_RS08190	COG4628	conserved protein (DUF2132)
CFH90_RS08215	COG0656	L-ascorbic acid biosynthetic process
CFH90_RS08220	COG1073	alpha beta
CFH90_RS08235	COG1064	alcohol dehydrogenase
CFH90_RS08255	COG2814	Major facilitator Superfamily
CFH90_RS08360	COG2801	Transposase and inactivated derivatives
CFH90_RS08375	COG1230	cation diffusion facilitator family transporter
CFH90_RS08380	COG0730	response to heat
CFH90_RS08385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_RS08505	COG0300	oxidoreductase activity
CFH90_RS08515	COG1022	Amp-dependent synthetase and ligase
CFH90_RS08525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFH90_RS08530	COG0842	Transport permease protein
CFH90_RS08535	COG1129	ABC transporter
CFH90_RS08535	COG0842	Transport permease protein
CFH90_RS08540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_RS08575	COG0745	RESPONSE REGULATOR receiver
CFH90_RS08580	COG0642	Histidine kinase
CFH90_RS08595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFH90_RS08625	COG0640	Transcriptional regulator
CFH90_RS08675	COG0596	Alpha beta hydrolase
CFH90_RS08745	COG0864	Transcriptional regulator
CFH90_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS08775	COG2814	Major facilitator Superfamily
CFH90_RS08785	COG2199	diguanylate cyclase activity
CFH90_RS08830	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS08835	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS08890	COG3293	Transposase
CFH90_RS08935	COG1464	Belongs to the NlpA lipoprotein family
CFH90_RS08940	COG1464	Belongs to the NlpA lipoprotein family
CFH90_RS08945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFH90_RS08950	COG2011	ABC-type metal ion transport system permease component
CFH90_RS08960	COG0012	GTP binding
CFH90_RS08985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFH90_RS09000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFH90_RS09035	COG0386	Belongs to the glutathione peroxidase family
CFH90_RS09040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFH90_RS09045	COG0436	Aminotransferase
CFH90_RS09085	COG3634	alkyl hydroperoxide reductase activity
CFH90_RS09110	COG2070	2-Nitropropane dioxygenase
CFH90_RS09145	COG0537	adenosine 5'-monophosphoramidase activity
CFH90_RS09170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFH90_RS09175	COG0776	regulation of translation
CFH90_RS09190	COG1959	2 iron, 2 sulfur cluster binding
CFH90_RS09200	COG0822	iron-sulfur transferase activity
CFH90_RS09205	COG0316	Belongs to the HesB IscA family
CFH90_RS09235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFH90_RS09255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFH90_RS09265	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFH90_RS09265	COG0506	proline dehydrogenase activity
CFH90_RS09265	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFH90_RS09300	COG3781	membrane
CFH90_RS09305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFH90_RS09315	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFH90_RS09335	COG0697	spore germination
CFH90_RS09350	COG0126	phosphoglycerate kinase activity
CFH90_RS09360	COG0424	maF-like protein
CFH90_RS09370	COG2850	peptidyl-arginine hydroxylation
CFH90_RS09375	COG4585	Histidine kinase
CFH90_RS09380	COG2197	response regulator
CFH90_RS09385	COG0069	glutamate synthase activity
CFH90_RS09405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFH90_RS09410	COG1454	alcohol dehydrogenase
CFH90_RS09415	COG0824	Thioesterase
CFH90_RS09420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFH90_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS09445	COG0183	Belongs to the thiolase family
CFH90_RS09460	COG0583	DNA-binding transcription factor activity
CFH90_RS09465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFH90_RS09475	COG3135	benzoate transporter
CFH90_RS09480	COG1309	transcriptional regulator
CFH90_RS09485	COG2076	Multidrug Resistance protein
CFH90_RS09500	COG0589	response to stress
CFH90_RS09510	COG0308	aminopeptidase N
CFH90_RS09535	COG1253	flavin adenine dinucleotide binding
CFH90_RS09555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFH90_RS09560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFH90_RS09575	COG2431	L-lysine efflux transmembrane transporter activity
CFH90_RS09590	COG0776	regulation of translation
CFH90_RS09610	COG0590	tRNA wobble adenosine to inosine editing
CFH90_RS09620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFH90_RS09655	COG0084	hydrolase, TatD family'
CFH90_RS09675	COG1663	tetraacyldisaccharide 4'-kinase activity
CFH90_RS09680	COG1132	(ABC) transporter
CFH90_RS09690	COG0811	peptide transport
CFH90_RS09695	COG1475	DNA binding
CFH90_RS09700	COG1192	Involved in chromosome partitioning
CFH90_RS09710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFH90_RS09715	COG3178	'Phosphotransferase
CFH90_RS09725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFH90_RS09730	COG1923	regulation of RNA biosynthetic process
CFH90_RS09740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFH90_RS09745	COG0802	atpase or kinase
CFH90_RS09770	COG2707	UPF0756 membrane protein
CFH90_RS09775	COG2814	Major facilitator Superfamily
CFH90_RS09780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFH90_RS09785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFH90_RS09795	COG1454	alcohol dehydrogenase
CFH90_RS09820	COG4303	Ethanolamine ammonia lyase large subunit
CFH90_RS09845	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS09855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFH90_RS09855	COG0519	Catalyzes the synthesis of GMP from XMP
CFH90_RS09875	COG2353	YceI-like domain
CFH90_RS09890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFH90_RS09895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFH90_RS09950	COG0352	thiamine-phosphate diphosphorylase activity
CFH90_RS09955	COG3293	Transposase
CFH90_RS09990	COG0612	Peptidase, M16
CFH90_RS10000	COG1823	symporter activity
CFH90_RS10005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_RS10050	COG2351	hydroxyisourate hydrolase activity
CFH90_RS10060	COG1686	Belongs to the peptidase S11 family
CFH90_RS10065	COG1252	NADH dehydrogenase
CFH90_RS10070	COG1047	Peptidyl-prolyl cis-trans
CFH90_RS10080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFH90_RS10080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFH90_RS10105	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS10110	COG2819	hydrolase of the alpha beta superfamily
CFH90_RS10125	COG0372	Belongs to the citrate synthase family
CFH90_RS10155	COG0542	response to heat
CFH90_RS10160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFH90_RS10180	COG3293	Transposase
CFH90_RS10190	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFH90_RS10195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFH90_RS10205	COG0569	domain protein
CFH90_RS10210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFH90_RS10230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFH90_RS10240	COG1585	Membrane protein implicated in regulation of membrane protease activity
CFH90_RS10255	COG1294	oxidase, subunit
CFH90_RS10260	COG4890	Cyd operon protein YbgT
CFH90_RS10275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFH90_RS10280	COG1309	transcriptional regulator
CFH90_RS10285	COG1012	belongs to the aldehyde dehydrogenase family
CFH90_RS10295	COG0579	oxidoreductase
CFH90_RS10310	COG0772	Belongs to the SEDS family
CFH90_RS10325	COG0148	phosphopyruvate hydratase activity
CFH90_RS10345	COG0583	DNA-binding transcription factor activity
CFH90_RS10355	COG2814	Major facilitator Superfamily
CFH90_RS10370	COG1902	pentaerythritol trinitrate reductase activity
CFH90_RS10370	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFH90_RS10380	COG2267	carboxylic ester hydrolase activity
CFH90_RS10390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFH90_RS10395	COG0702	epimerase
CFH90_RS10425	COG3293	Transposase
CFH90_RS10455	COG1011	Hydrolase
CFH90_RS10460	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CFH90_RS10465	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFH90_RS10470	COG2137	regulation of response to DNA damage stimulus
CFH90_RS10500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFH90_RS10520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFH90_RS10535	COG0575	Belongs to the CDS family
CFH90_RS10540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFH90_RS10560	COG3852	Histidine kinase
CFH90_RS10575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFH90_RS10580	COG0583	DNA-binding transcription factor activity
CFH90_RS10585	COG0024	Methionine aminopeptidase
CFH90_RS10610	COG1113	amino acid transport
CFH90_RS10620	COG0786	glutamate:sodium symporter activity
CFH90_RS10625	COG4773	Receptor
CFH90_RS10685	COG0729	surface antigen
CFH90_RS10710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFH90_RS10725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFH90_RS10730	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS10765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_RS10770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFH90_RS10775	COG2890	protein-(glutamine-N5) methyltransferase activity
CFH90_RS10780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFH90_RS10795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFH90_RS10825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFH90_RS10830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFH90_RS10835	COG1845	cytochrome c oxidase, subunit III
CFH90_RS10840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFH90_RS10860	COG0360	Binds together with S18 to 16S ribosomal RNA
CFH90_RS10875	COG0305	Participates in initiation and elongation during chromosome replication
CFH90_RS10880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFH90_RS10895	COG1305	Transglutaminase-like
CFH90_RS10905	COG2308	Evidence 4 Homologs of previously reported genes of
CFH90_RS10920	COG0445	tRNA wobble uridine modification
CFH90_RS10950	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CFH90_RS10955	COG0138	bifunctional purine biosynthesis protein purh
CFH90_RS10960	COG0151	Belongs to the GarS family
CFH90_RS10975	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFH90_RS11000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFH90_RS11005	COG2011	ABC-type metal ion transport system permease component
CFH90_RS11045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFH90_RS11055	COG4122	O-methyltransferase activity
CFH90_RS11075	COG1137	ATPase activity
CFH90_RS11080	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFH90_RS11090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CFH90_RS11095	COG0517	IMP dehydrogenase activity
CFH90_RS11095	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFH90_RS11105	COG0406	alpha-ribazole phosphatase activity
CFH90_RS11110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFH90_RS11145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFH90_RS11155	COG0243	molybdopterin cofactor binding
CFH90_RS11160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_RS11165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_RS11170	COG2223	nitrite transmembrane transporter activity
CFH90_RS11180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_RS11180	COG1116	anion transmembrane transporter activity
CFH90_RS11200	COG1643	Atp-dependent helicase
CFH90_RS11210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_RS11250	COG0515	serine threonine protein kinase
CFH90_RS11250	COG2815	serine threonine protein kinase
CFH90_RS11280	COG1610	YqeY-like protein
CFH90_RS11285	COG4783	chaperone-mediated protein folding
CFH90_RS11340	COG0778	Nitroreductase
CFH90_RS11350	COG0513	Belongs to the DEAD box helicase family
CFH90_RS11355	COG1278	Cold shock
CFH90_RS11370	COG2363	Small membrane protein
CFH90_RS11390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CFH90_RS11395	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFH90_RS11400	COG0625	glutathione transferase activity
CFH90_RS11405	COG0659	secondary active sulfate transmembrane transporter activity
CFH90_RS11415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFH90_RS11445	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS11450	COG1309	transcriptional regulator
CFH90_RS11455	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS11460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFH90_RS11470	COG4770	biotin carboxylase activity
CFH90_RS11485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_RS11490	COG2031	fatty acid transporter
CFH90_RS11510	COG0540	Belongs to the ATCase OTCase family
CFH90_RS11535	COG1765	OsmC-like protein
CFH90_RS11545	COG0667	Aldo Keto reductase
CFH90_RS11560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFH90_RS11575	COG1522	sequence-specific DNA binding
CFH90_RS11580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFH90_RS11595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CFH90_RS11605	COG0527	aspartate kinase activity
CFH90_RS11615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFH90_RS11630	COG3038	cytochrome b561
CFH90_RS11640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFH90_RS11645	COG2252	PERMEase
CFH90_RS11655	COG0415	Belongs to the DNA photolyase family
CFH90_RS11685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFH90_RS11690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFH90_RS11700	COG0693	protein deglycase activity
CFH90_RS11705	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS11710	COG1301	dicarboxylic acid transport
CFH90_RS11725	COG3139	Protein of unknown function (DUF1315)
CFH90_RS11730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFH90_RS11735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFH90_RS11745	COG0494	nUDIX hydrolase
CFH90_RS11755	COG0642	Histidine kinase
CFH90_RS11770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFH90_RS11780	COG1720	tRNA m6t6A37 methyltransferase activity
CFH90_RS11815	COG0826	peptidase U32
CFH90_RS11820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFH90_RS11825	COG3634	alkyl hydroperoxide reductase activity
CFH90_RS11850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFH90_RS11905	COG0235	Class ii aldolase
CFH90_RS11910	COG2169	Transcriptional regulator
CFH90_RS11930	COG4149	molybdate abc transporter
CFH90_RS11935	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFH90_RS11945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFH90_RS11960	COG0315	cyclic pyranopterin monophosphate synthase activity
CFH90_RS11960	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFH90_RS11965	COG0303	'Molybdopterin
CFH90_RS11985	COG3177	Filamentation induced by cAMP protein fic
CFH90_RS11990	COG0583	DNA-binding transcription factor activity
CFH90_RS11995	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS12000	COG2301	Belongs to the HpcH HpaI aldolase family
CFH90_RS12005	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFH90_RS12010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFH90_RS12015	COG0583	DNA-binding transcription factor activity
CFH90_RS12025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_RS12030	COG2814	Major facilitator Superfamily
CFH90_RS12040	COG4829	muconolactone delta-isomerase
CFH90_RS12045	COG0427	acetyl-CoA hydrolase
CFH90_RS12050	COG0183	Belongs to the thiolase family
CFH90_RS12085	COG3586	endonuclease activity
CFH90_RS12110	COG2184	nucleotidyltransferase activity
CFH90_RS12145	COG0582	viral genome integration into host DNA
CFH90_RS12155	COG1131	(ABC) transporter
CFH90_RS12160	COG0842	Transport permease protein
CFH90_RS12175	COG2951	lytic endotransglycosylase activity
CFH90_RS12215	COG0052	Belongs to the universal ribosomal protein uS2 family
CFH90_RS12235	COG2175	clavaminate synthase activity
CFH90_RS12250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_RS12255	COG0842	Transport permease protein
CFH90_RS12290	COG1280	lysine exporter protein (LysE YggA)
CFH90_RS12295	COG1522	sequence-specific DNA binding
CFH90_RS12300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFH90_RS12310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CFH90_RS12320	COG0019	diaminopimelate decarboxylase activity
CFH90_RS12330	COG1113	amino acid transport
CFH90_RS12340	COG1115	amino acid carrier protein
CFH90_RS12355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFH90_RS12360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFH90_RS12365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFH90_RS12370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFH90_RS12410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFH90_RS12415	COG3161	chorismate lyase activity
CFH90_RS12425	COG0174	glutamine synthetase
CFH90_RS12430	COG0512	Glutamine amidotransferase of anthranilate synthase
CFH90_RS12435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFH90_RS12440	COG0134	indole-3-glycerol-phosphate synthase activity
CFH90_RS12460	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS12475	COG0302	gtp cyclohydrolase
CFH90_RS12485	COG3706	GGDEF domain
CFH90_RS12500	COG3739	integral membrane protein
CFH90_RS12520	COG1741	Belongs to the pirin family
CFH90_RS12535	COG1309	transcriptional regulator
CFH90_RS12570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFH90_RS12575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CFH90_RS12585	COG0037	tRNA processing
CFH90_RS12590	COG0741	lytic transglycosylase activity
CFH90_RS12595	COG0501	Belongs to the peptidase M48B family
CFH90_RS12610	COG2239	Acts as a magnesium transporter
CFH90_RS12640	COG1253	flavin adenine dinucleotide binding
CFH90_RS12645	COG2851	Citrate transporter
CFH90_RS12685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFH90_RS12690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFH90_RS12715	COG0505	Belongs to the CarA family
CFH90_RS12720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFH90_RS12760	COG3695	enzyme binding
CFH90_RS12775	COG2321	neutral zinc metallopeptidase
CFH90_RS12780	COG2354	Protein conserved in bacteria
CFH90_RS12790	COG1585	Membrane protein implicated in regulation of membrane protease activity
CFH90_RS12795	COG2268	Band 7 protein
CFH90_RS12805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFH90_RS12815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFH90_RS12830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFH90_RS12835	COG1053	succinate dehydrogenase
CFH90_RS12840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CFH90_RS12845	COG2009	succinate dehydrogenase
CFH90_RS12875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFH90_RS12875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CFH90_RS12900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFH90_RS12925	COG0564	pseudouridine synthase activity
CFH90_RS12935	COG0358	DNA primase activity
CFH90_RS12950	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CFH90_RS12980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFH90_RS12985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFH90_RS13045	COG0586	Pfam SNARE associated Golgi protein
CFH90_RS13080	COG2921	Belongs to the UPF0250 family
CFH90_RS13085	COG0321	lipoyl(octanoyl) transferase activity
CFH90_RS13100	COG0531	amino acid
CFH90_RS13120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFH90_RS13125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFH90_RS13125	COG1648	precorrin-2 dehydrogenase activity
CFH90_RS13130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFH90_RS13140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFH90_RS13150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFH90_RS13170	COG0671	phosphoesterase, PA-phosphatase related
CFH90_RS13175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_RS13185	COG1538	Outer membrane efflux protein
CFH90_RS13190	COG0393	Putative heavy-metal-binding
CFH90_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS13215	COG0525	valine-tRNA ligase activity
CFH90_RS13250	COG0583	DNA-binding transcription factor activity
CFH90_RS13260	COG1278	Cold shock
CFH90_RS13275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFH90_RS13280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFH90_RS13285	COG0713	ATP synthesis coupled electron transport
CFH90_RS13295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFH90_RS13310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFH90_RS13330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFH90_RS13340	COG2205	protein histidine kinase activity
CFH90_RS13345	COG0745	RESPONSE REGULATOR receiver
CFH90_RS13355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFH90_RS13415	COG0439	Biotin carboxylase
CFH90_RS13420	COG1802	Transcriptional regulator
CFH90_RS13425	COG1652	LysM domain
CFH90_RS13435	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS13450	COG1399	metal-binding, possibly nucleic acid-binding protein
CFH90_RS13455	COG3101	peptidyl-lysine hydroxylation
CFH90_RS13460	COG0009	L-threonylcarbamoyladenylate synthase
CFH90_RS13475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFH90_RS13480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFH90_RS13525	COG4106	trans-aconitate 2-methyltransferase activity
CFH90_RS13540	COG0596	Alpha beta hydrolase
CFH90_RS13540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_RS13540	COG2226	methyltransferase
CFH90_RS13550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFH90_RS13555	COG2193	ferroxidase activity
CFH90_RS13570	COG4774	siderophore transport
CFH90_RS13575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFH90_RS13580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFH90_RS13585	COG3115	cell septum assembly
CFH90_RS13590	COG1196	nuclear chromosome segregation
CFH90_RS13600	COG0730	response to heat
CFH90_RS13620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFH90_RS13645	COG0488	(ABC) transporter
CFH90_RS13670	COG3422	double-strand break repair
CFH90_RS13680	COG2824	Alkylphosphonate utilization operon protein PhnA
CFH90_RS13685	COG3189	MarR family transcriptional regulator
CFH90_RS13705	COG0564	pseudouridine synthase activity
CFH90_RS13710	COG0346	lactoylglutathione lyase activity
CFH90_RS13745	COG1487	ribonuclease activity
CFH90_RS13750	COG4456	Virulence-associated protein
CFH90_RS13770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFH90_RS13800	COG1902	pentaerythritol trinitrate reductase activity
CFH90_RS13815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFH90_RS13825	COG1970	mechanosensitive ion channel activity
CFH90_RS13830	COG1217	gtp-binding protein TYPA
CFH90_RS13835	COG2233	PERMEase
CFH90_RS13840	COG2813	Specifically methylates the guanine in position
CFH90_RS13845	COG0833	amino acid
CFH90_RS13860	COG0183	Belongs to the thiolase family
CFH90_RS13880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_RS13895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFH90_RS13900	COG2207	Transcriptional regulator
CFH90_RS13905	COG0183	Belongs to the thiolase family
CFH90_RS13910	COG1024	Enoyl-CoA hydratase
CFH90_RS13910	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFH90_RS13930	COG1272	protein, Hemolysin III
CFH90_RS13935	COG0477	Major facilitator Superfamily
CFH90_RS13945	COG1408	metallophosphoesterase
CFH90_RS13950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFH90_RS13960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFH90_RS13985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFH90_RS13990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFH90_RS14010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFH90_RS14015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFH90_RS14020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFH90_RS14030	COG0625	glutathione transferase activity
CFH90_RS14035	COG2969	positive regulation of protein catabolic process
CFH90_RS14050	COG3293	Transposase
CFH90_RS14100	COG2853	Lipoprotein
CFH90_RS14105	COG2208	phosphoserine phosphatase activity
CFH90_RS14115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFH90_RS14120	COG1764	response to oxidative stress
CFH90_RS14150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFH90_RS14150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFH90_RS14165	COG0037	tRNA processing
CFH90_RS14175	COG0248	Ppx GppA phosphatase
CFH90_RS14200	COG0072	phenylalanine-tRNA ligase activity
CFH90_RS14245	COG1238	metal cluster binding
CFH90_RS14255	COG0625	glutathione transferase activity
CFH90_RS14275	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS14280	COG3028	Belongs to the UPF0307 family
CFH90_RS14290	COG1660	Displays ATPase and GTPase activities
CFH90_RS14295	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFH90_RS14305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFH90_RS14310	COG0617	tRNA 3'-terminal CCA addition
CFH90_RS14315	COG1555	photosystem II stabilization
CFH90_RS14320	COG3956	TIGRFAM MazG family protein
CFH90_RS14330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFH90_RS14345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFH90_RS14350	COG5002	protein histidine kinase activity
CFH90_RS14350	COG0784	Response regulator, receiver
CFH90_RS14350	COG2205	protein histidine kinase activity
CFH90_RS14355	COG1024	Enoyl-CoA hydratase
CFH90_RS14360	COG2084	Dehydrogenase
CFH90_RS14365	COG3622	Belongs to the hyi family
CFH90_RS14380	COG0004	ammonium transporteR
CFH90_RS14405	COG2814	Major facilitator Superfamily
CFH90_RS14420	COG4638	Rieske (2fe-2S)
CFH90_RS14425	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CFH90_RS14430	COG0543	2 iron, 2 sulfur cluster binding
CFH90_RS14430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFH90_RS14440	COG3385	transposase activity
CFH90_RS14475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_RS14485	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS14520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CFH90_RS14535	COG0732	type I restriction modification DNA specificity domain
CFH90_RS14545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CFH90_RS14815	COG3620	sequence-specific DNA binding
CFH90_RS14870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFH90_RS14885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CFH90_RS14895	COG0084	hydrolase, TatD family'
CFH90_RS14910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFH90_RS14925	COG0793	Belongs to the peptidase S41A family
CFH90_RS14950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFH90_RS14955	COG0857	belongs to the CobB CobQ family
CFH90_RS14955	COG0280	phosphate acetyltransferase
CFH90_RS14965	COG2318	DinB family
CFH90_RS14975	COG1917	Cupin 2, conserved barrel domain protein
CFH90_RS14975	COG2207	Transcriptional regulator
CFH90_RS14985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFH90_RS14985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CFH90_RS15005	COG0740	serine-type endopeptidase activity
CFH90_RS15015	COG4771	TonB-dependent receptor
CFH90_RS15020	COG4774	siderophore transport
CFH90_RS15035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFH90_RS15045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_RS15045	COG2813	Specifically methylates the guanine in position
CFH90_RS15150	COG0788	formyltetrahydrofolate deformylase activity
CFH90_RS15175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFH90_RS15175	COG4651	solute:proton antiporter activity
CFH90_RS15195	COG0210	DNA helicase
CFH90_RS15200	COG1929	Belongs to the glycerate kinase type-1 family
CFH90_RS15240	COG2900	Belongs to the SlyX family
CFH90_RS15245	COG0488	(ABC) transporter
CFH90_RS15255	COG1560	Kdo2-lipid A biosynthetic process
CFH90_RS15315	COG0473	3-isopropylmalate dehydrogenase activity
CFH90_RS15330	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFH90_RS15340	COG0583	DNA-binding transcription factor activity
CFH90_RS15375	COG1280	lysine exporter protein (LysE YggA)
CFH90_RS15390	COG1960	acyl-CoA dehydrogenase activity
CFH90_RS15440	COG0583	DNA-binding transcription factor activity
CFH90_RS15455	COG0564	pseudouridine synthase activity
CFH90_RS15465	COG1530	ribonuclease E activity
CFH90_RS15470	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS15495	COG1983	PspC domain protein
CFH90_RS15520	COG0751	glycine-tRNA ligase activity
CFH90_RS15555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFH90_RS15570	COG2226	methyltransferase
CFH90_RS15585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFH90_RS15585	COG0493	'glutamate synthase
CFH90_RS15595	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFH90_RS15605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_RS15610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFH90_RS15620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFH90_RS15630	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CFH90_RS15630	COG0644	oxidoreductase
CFH90_RS15640	COG0425	Belongs to the sulfur carrier protein TusA family
CFH90_RS15645	COG4535	Mg2 and Co2 transporter CorC
CFH90_RS15650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFH90_RS15655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFH90_RS15675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFH90_RS15685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFH90_RS15705	COG2841	Protein conserved in bacteria
CFH90_RS15710	COG0598	Magnesium transport protein CorA
CFH90_RS15715	COG1185	polyribonucleotide nucleotidyltransferase activity
CFH90_RS15725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFH90_RS15730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFH90_RS15735	COG1074	ATP-dependent DNA helicase activity
CFH90_RS15740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CFH90_RS15770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFH90_RS15785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFH90_RS15795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFH90_RS15800	COG2111	Na H antiporter
CFH90_RS15800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFH90_RS15805	COG1006	Multisubunit Na H antiporter MnhC subunit
CFH90_RS15810	COG0651	ATP synthesis coupled electron transport
CFH90_RS15815	COG1863	multisubunit Na H antiporter MnhE subunit
CFH90_RS15820	COG2212	antiporter activity
CFH90_RS15825	COG1320	monovalent cation:proton antiporter activity
CFH90_RS15830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFH90_RS15840	COG0195	Participates in both transcription termination and antitermination
CFH90_RS15900	COG0237	dephospho-CoA kinase activity
CFH90_RS15910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFH90_RS15920	COG0497	DNA recombination
CFH90_RS15925	COG1678	Uncharacterized ACR, COG1678
CFH90_RS15930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFH90_RS15945	COG1289	transmembrane transporter activity
CFH90_RS15960	COG1132	(ABC) transporter
CFH90_RS15965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFH90_RS16035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CFH90_RS16060	COG0326	Molecular chaperone. Has ATPase activity
CFH90_RS16070	COG3047	cAMP biosynthetic process
CFH90_RS16075	COG2056	Na+-H+ antiporter family
CFH90_RS16100	COG3385	transposase activity
CFH90_RS16105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFH90_RS16110	COG0085	RNA polymerase activity
CFH90_RS16115	COG0222	ribosome binding
CFH90_RS16120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFH90_RS16125	COG0081	regulation of translation
CFH90_RS16130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFH90_RS16150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFH90_RS16180	COG0546	phosphoglycolate phosphatase activity
CFH90_RS16210	COG0824	Thioesterase
CFH90_RS16230	COG0181	hydroxymethylbilane synthase activity
CFH90_RS16240	COG3275	phosphorelay sensor kinase activity
CFH90_RS16260	COG1538	Outer membrane efflux protein
CFH90_RS16270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFH90_RS16280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFH90_RS16285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFH90_RS16290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFH90_RS16295	COG0772	Belongs to the SEDS family
CFH90_RS16300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFH90_RS16320	COG4974	Belongs to the 'phage' integrase family
CFH90_RS16325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_RS16335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFH90_RS16345	COG2197	response regulator
CFH90_RS16360	COG0793	Belongs to the peptidase S41A family
CFH90_RS16365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFH90_RS16370	COG0795	lipopolysaccharide-transporting ATPase activity
CFH90_RS16375	COG0795	lipopolysaccharide-transporting ATPase activity
CFH90_RS16395	COG0586	Pfam SNARE associated Golgi protein
CFH90_RS16410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFH90_RS16410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFH90_RS16420	COG0004	ammonium transporteR
CFH90_RS16425	COG0347	Belongs to the P(II) protein family
CFH90_RS16435	COG0606	chelatase, subunit chli
CFH90_RS16455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFH90_RS16470	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_RS16485	COG0477	Major facilitator Superfamily
CFH90_RS16490	COG2860	membrane
CFH90_RS16495	COG3012	SEC-C Motif Domain Protein
CFH90_RS16500	COG1253	flavin adenine dinucleotide binding
CFH90_RS16520	COG2814	Major facilitator Superfamily
CFH90_RS16530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFH90_RS16610	COG0758	DNA mediated transformation
CFH90_RS16620	COG0697	spore germination
CFH90_RS16630	COG0386	Belongs to the glutathione peroxidase family
CFH90_RS16665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFH90_RS16715	COG1121	(ABC) transporter
CFH90_RS16720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFH90_RS16725	COG1683	Conserved Protein
CFH90_RS16735	COG2837	iron assimilation
CFH90_RS16765	COG1388	LysM domain
CFH90_RS16765	COG0791	NLP P60 protein
CFH90_RS16775	COG0281	malic enzyme
CFH90_RS16830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFH90_RS16830	COG0519	Catalyzes the synthesis of GMP from XMP
CFH90_RS16835	COG3111	PFAM Bacterial OB fold (BOF) protein
CFH90_RS16845	COG0586	Pfam SNARE associated Golgi protein
CFH90_RS16860	COG1192	Involved in chromosome partitioning
CFH90_RS16870	COG0271	Belongs to the BolA IbaG family
CFH90_RS16890	COG3655	Transcriptional regulator
CFH90_RS16915	COG1203	CRISPR-associated helicase, Cas3
CFH90_RS17025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFH90_RS17050	COG0640	Transcriptional regulator
CFH90_RS17075	COG0642	Histidine kinase
CFH90_RS17100	COG3550	peptidyl-serine autophosphorylation
CFH90_RS17105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFH90_RS17145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFH90_RS17160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFH90_RS17160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFH90_RS17160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CFH90_RS17165	COG1105	Belongs to the carbohydrate kinase PfkB family
CFH90_RS17170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFH90_RS17170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFH90_RS17175	COG0583	DNA-binding transcription factor activity
CFH90_RS17180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFH90_RS17195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFH90_RS17205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CFH90_RS17210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFH90_RS17220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFH90_RS17260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFH90_RS17265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFH90_RS17280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFH90_RS17290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFH90_RS17300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFH90_RS17305	COG0438	transferase activity, transferring glycosyl groups
CFH90_RS17315	COG0367	asparagine synthase
CFH90_RS17325	COG0438	transferase activity, transferring glycosyl groups
CFH90_RS17340	COG0110	maltose O-acetyltransferase activity
CFH90_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS17350	COG1083	cytidylyl-transferase
CFH90_RS17355	COG0673	inositol 2-dehydrogenase activity
CFH90_RS17360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFH90_RS17370	COG2089	acid synthase
CFH90_RS17375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFH90_RS17380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFH90_RS17390	COG2244	polysaccharide biosynthetic process
CFH90_RS17405	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFH90_RS17420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFH90_RS17455	COG0728	peptidoglycan biosynthetic process
CFH90_RS17460	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFH90_RS17470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFH90_RS17480	COG3307	-O-antigen
CFH90_RS17485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_RS17490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFH90_RS17495	COG0546	phosphoglycolate phosphatase activity
CFH90_RS17500	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_RS17520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CFH90_RS17520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFH90_RS17525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_RS17530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_RS17535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFH90_RS17540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFH90_RS17545	COG1116	anion transmembrane transporter activity
CFH90_RS17550	COG1309	transcriptional regulator
CFH90_RS17565	COG0196	riboflavin kinase activity
CFH90_RS17570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFH90_RS17575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFH90_RS17580	COG1047	Peptidyl-prolyl cis-trans
CFH90_RS17595	COG2133	pyrroloquinoline quinone binding
CFH90_RS17625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFH90_RS17630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFH90_RS17635	COG2951	lytic endotransglycosylase activity
CFH90_RS17640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFH90_RS17655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFH90_RS17675	COG0861	Integral membrane protein TerC family
CFH90_RS17695	COG0402	S-adenosylhomocysteine deaminase activity
CFH90_RS17715	COG1230	cation diffusion facilitator family transporter
CFH90_RS17735	COG0706	membrane insertase activity
CFH90_RS17740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFH90_RS17810	COG0778	Nitroreductase
CFH90_RS17855	COG2871	sodium ion transport
CFH90_RS17900	COG0583	DNA-binding transcription factor activity
CFH90_RS17910	COG4680	protein conserved in bacteria
CFH90_RS17915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_RS17920	COG0183	Belongs to the thiolase family
CFH90_RS17925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_RS17930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFH90_RS17935	COG4829	muconolactone delta-isomerase
CFH90_RS17940	COG4948	Mandelate Racemase Muconate Lactonizing
CFH90_RS17945	COG0583	DNA-binding transcription factor activity
CFH90_RS17950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CFH90_RS17955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFH90_RS17960	COG3485	protocatechuate 3,4-dioxygenase
CFH90_RS18010	COG0582	viral genome integration into host DNA
CFH90_RS18080	COG3971	2-oxopent-4-enoate hydratase activity
CFH90_RS18085	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CFH90_RS18090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFH90_RS18095	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFH90_RS18120	COG2801	Transposase and inactivated derivatives
CFH90_RS18155	COG0659	secondary active sulfate transmembrane transporter activity
CFH90_RS18160	COG2801	Transposase and inactivated derivatives
CFH90_RS18165	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CFH90_RS18200	COG0753	catalase activity
CFH90_RS18220	COG0477	Major facilitator Superfamily
CFH90_RS18235	COG1475	DNA binding
CFH90_RS18240	COG1192	Involved in chromosome partitioning
CFH90_RS18245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFH90_RS18250	COG1192	Involved in chromosome partitioning
CFH90_RS18295	COG0789	Transcriptional regulator
CFH90_RS18390	COG3077	Addiction module antitoxin, RelB DinJ family