locus-tag	class	description
RZ95_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RZ95_RS00010	COG0592	DNA-directed DNA polymerase activity
RZ95_RS00020	COG0187	DNA topoisomerase II activity
RZ95_RS00030	COG0488	(ABC) transporter
RZ95_RS00095	COG0657	acetylesterase activity
RZ95_RS00115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RZ95_RS00145	COG2814	Major facilitator Superfamily
RZ95_RS00155	COG0733	neurotransmitter:sodium symporter activity
RZ95_RS00175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RZ95_RS00175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RZ95_RS00190	COG0129	dihydroxy-acid dehydratase activity
RZ95_RS00200	COG4774	siderophore transport
RZ95_RS00210	COG0583	DNA-binding transcription factor activity
RZ95_RS00215	COG2233	PERMEase
RZ95_RS00225	COG1309	transcriptional regulator
RZ95_RS00245	COG0484	heat shock protein binding
RZ95_RS00270	COG0436	Aminotransferase
RZ95_RS00275	COG1064	alcohol dehydrogenase
RZ95_RS00280	COG2818	Glycosylase
RZ95_RS00310	COG2983	Belongs to the UPF0260 family
RZ95_RS00315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RZ95_RS00345	COG4160	amino acid transport
RZ95_RS00350	COG4215	(ABC) transporter
RZ95_RS00355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RZ95_RS00375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RZ95_RS00390	COG0385	Bile acid
RZ95_RS00420	COG3385	transposase activity
RZ95_RS00465	COG0534	Mate efflux family protein
RZ95_RS00470	COG0436	Aminotransferase
RZ95_RS00475	COG2733	membrane
RZ95_RS00490	COG2918	glutathione biosynthetic process
RZ95_RS00495	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RZ95_RS00505	COG3150	esterase
RZ95_RS00590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RZ95_RS00605	COG1393	Belongs to the ArsC family
RZ95_RS00610	COG0708	Exodeoxyribonuclease III
RZ95_RS00620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RZ95_RS00635	COG1846	Transcriptional regulator
RZ95_RS00640	COG0386	Belongs to the glutathione peroxidase family
RZ95_RS00645	COG0189	ligase activity
RZ95_RS00655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RZ95_RS00665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RZ95_RS00675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RZ95_RS00705	COG2119	membrane
RZ95_RS00710	COG0426	domain, Protein
RZ95_RS00710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RZ95_RS00735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RZ95_RS00760	COG1902	pentaerythritol trinitrate reductase activity
RZ95_RS00765	COG1519	Transferase
RZ95_RS00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RZ95_RS00775	COG0668	transmembrane transport
RZ95_RS00780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RZ95_RS00785	COG0307	riboflavin synthase, alpha
RZ95_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS00805	COG0431	NADPH-dependent FMN reductase
RZ95_RS00820	COG0784	Response regulator, receiver
RZ95_RS00820	COG2205	protein histidine kinase activity
RZ95_RS00825	COG3162	membrane
RZ95_RS00830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RZ95_RS00840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RZ95_RS00865	COG3706	GGDEF domain
RZ95_RS00885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RZ95_RS00885	COG0352	thiamine-phosphate diphosphorylase activity
RZ95_RS00885	COG0351	phosphomethylpyrimidine kinase
RZ95_RS00900	COG2814	Major facilitator Superfamily
RZ95_RS00905	COG0629	single-stranded DNA binding
RZ95_RS00930	COG2826	transposase and inactivated derivatives, IS30 family
RZ95_RS00935	COG2801	Transposase and inactivated derivatives
RZ95_RS00955	COG2132	Multicopper oxidase
RZ95_RS00970	COG2205	protein histidine kinase activity
RZ95_RS00975	COG3174	membrane
RZ95_RS00980	COG2217	Heavy metal translocating P-type atpase
RZ95_RS01050	COG0732	type I restriction modification DNA specificity domain
RZ95_RS01070	COG0583	DNA-binding transcription factor activity
RZ95_RS01075	COG1301	dicarboxylic acid transport
RZ95_RS01095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RZ95_RS01110	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RZ95_RS01185	COG0582	viral genome integration into host DNA
RZ95_RS01215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RZ95_RS01240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RZ95_RS01245	COG1278	Cold shock
RZ95_RS01260	COG0531	amino acid
RZ95_RS01265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RZ95_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RZ95_RS01330	COG0427	acetyl-CoA hydrolase
RZ95_RS01360	COG4221	oxidoreductase activity
RZ95_RS01365	COG2873	o-acetylhomoserine
RZ95_RS01370	COG0488	(ABC) transporter
RZ95_RS01395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RZ95_RS01410	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RZ95_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RZ95_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RZ95_RS01445	COG2226	methyltransferase
RZ95_RS01505	COG0069	glutamate synthase activity
RZ95_RS01505	COG0067	glutamate synthase
RZ95_RS01505	COG0070	glutamate synthase
RZ95_RS01510	COG0493	'glutamate synthase
RZ95_RS01520	COG1704	LemA family
RZ95_RS01525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RZ95_RS01550	COG4372	Transposase
RZ95_RS01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RZ95_RS01585	COG1758	RNA polymerase activity
RZ95_RS01590	COG0194	GDP metabolic process
RZ95_RS01605	COG0228	four-way junction DNA binding
RZ95_RS01610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RZ95_RS01620	COG0335	large ribosomal subunit rRNA binding
RZ95_RS01635	COG3335	DDE superfamily endonuclease
RZ95_RS01650	COG5380	lipid catabolic process
RZ95_RS01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RZ95_RS01670	COG5006	permease, DMT superfamily
RZ95_RS01675	COG5006	permease, DMT superfamily
RZ95_RS01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RZ95_RS01685	COG0277	FAD linked oxidase domain protein
RZ95_RS01710	COG2814	Major facilitator Superfamily
RZ95_RS01715	COG1289	transmembrane transporter activity
RZ95_RS01720	COG2032	superoxide dismutase activity
RZ95_RS01725	COG0628	permease
RZ95_RS01730	COG1192	Involved in chromosome partitioning
RZ95_RS01740	COG2226	methyltransferase
RZ95_RS01755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RZ95_RS01760	COG0254	rRNA binding
RZ95_RS01765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RZ95_RS01775	COG0534	Mate efflux family protein
RZ95_RS01785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RZ95_RS01795	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS01810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RZ95_RS01820	COG0408	coproporphyrinogen oxidase activity
RZ95_RS01825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RZ95_RS01845	COG0513	Belongs to the DEAD box helicase family
RZ95_RS01850	COG1127	ABC transporter
RZ95_RS01855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RZ95_RS01860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RZ95_RS01865	COG2854	intermembrane phospholipid transfer
RZ95_RS01875	COG0598	Magnesium transport protein CorA
RZ95_RS01885	COG0494	nUDIX hydrolase
RZ95_RS01890	COG1040	competence protein
RZ95_RS01895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RZ95_RS01925	COG2937	Belongs to the GPAT DAPAT family
RZ95_RS01930	COG1946	Acyl-CoA thioesterase
RZ95_RS01935	COG1301	dicarboxylic acid transport
RZ95_RS01950	COG1959	2 iron, 2 sulfur cluster binding
RZ95_RS01960	COG0433	COG0433 Predicted ATPase
RZ95_RS01980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RZ95_RS01985	COG0088	Forms part of the polypeptide exit tunnel
RZ95_RS02000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RZ95_RS02050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RZ95_RS02055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RZ95_RS02065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RZ95_RS02090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RZ95_RS02105	COG0202	RNA polymerase activity
RZ95_RS02110	COG0203	ribosomal protein L17
RZ95_RS02115	COG2072	flavoprotein involved in K transport
RZ95_RS02125	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS02130	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RZ95_RS02160	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
RZ95_RS02165	COG0339	signal peptide processing
RZ95_RS02170	COG2720	vancomycin resistance protein
RZ95_RS02175	COG0557	exoribonuclease II activity
RZ95_RS02205	COG0179	Fumarylacetoacetate (FAA) hydrolase
RZ95_RS02220	COG1295	ribonuclease BN
RZ95_RS02265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RZ95_RS02270	COG1702	phosphate starvation-inducible protein PhoH
RZ95_RS02275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RZ95_RS02280	COG0741	lytic transglycosylase activity
RZ95_RS02280	COG1196	nuclear chromosome segregation
RZ95_RS02280	COG0739	heme binding
RZ95_RS02290	COG0039	L-malate dehydrogenase activity
RZ95_RS02315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RZ95_RS02320	COG1183	phosphatidylcholine synthase activity
RZ95_RS02380	COG1607	acyl-coa hydrolase
RZ95_RS02395	COG1666	GTP binding
RZ95_RS02415	COG2350	Protein conserved in bacteria
RZ95_RS02425	COG0613	PHP domain protein
RZ95_RS02430	COG3781	membrane
RZ95_RS02440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RZ95_RS02465	COG1162	GTPase activity
RZ95_RS02470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RZ95_RS02505	COG1538	Outer membrane efflux protein
RZ95_RS02515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RZ95_RS02540	COG0028	Belongs to the TPP enzyme family
RZ95_RS02545	COG0440	acetolactate synthase activity
RZ95_RS02605	COG1426	Protein conserved in bacteria
RZ95_RS02625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RZ95_RS02650	COG1862	Preprotein translocase
RZ95_RS02665	COG0675	Transposase, IS605 OrfB family
RZ95_RS02675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RZ95_RS02685	COG0582	viral genome integration into host DNA
RZ95_RS02740	COG5002	protein histidine kinase activity
RZ95_RS02745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RZ95_RS02815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RZ95_RS02845	COG3223	Belongs to the PsiE family
RZ95_RS02850	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS02855	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS02865	COG2205	protein histidine kinase activity
RZ95_RS02870	COG0745	RESPONSE REGULATOR receiver
RZ95_RS02875	COG1113	amino acid transport
RZ95_RS02880	COG2315	Protein conserved in bacteria
RZ95_RS02885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RZ95_RS02905	COG2096	Adenosyltransferase
RZ95_RS02910	COG4206	TonB-dependent receptor
RZ95_RS02960	COG0285	dihydrofolate synthase activity
RZ95_RS02980	COG0450	alkyl hydroperoxide reductase
RZ95_RS03000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RZ95_RS03005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RZ95_RS03035	COG2199	diguanylate cyclase activity
RZ95_RS03090	COG4372	Transposase
RZ95_RS03110	COG2969	positive regulation of protein catabolic process
RZ95_RS03115	COG0625	glutathione transferase activity
RZ95_RS03125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RZ95_RS03130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RZ95_RS03140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RZ95_RS03145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RZ95_RS03170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RZ95_RS03180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RZ95_RS03185	COG1408	metallophosphoesterase
RZ95_RS03195	COG0477	Major facilitator Superfamily
RZ95_RS03200	COG1272	protein, Hemolysin III
RZ95_RS03220	COG1250	3-hydroxyacyl-CoA dehydrogenase
RZ95_RS03220	COG1024	Enoyl-CoA hydratase
RZ95_RS03225	COG0183	Belongs to the thiolase family
RZ95_RS03230	COG2207	Transcriptional regulator
RZ95_RS03235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RZ95_RS03250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RZ95_RS03270	COG0183	Belongs to the thiolase family
RZ95_RS03285	COG0833	amino acid
RZ95_RS03290	COG2813	Specifically methylates the guanine in position
RZ95_RS03295	COG2233	PERMEase
RZ95_RS03300	COG1217	gtp-binding protein TYPA
RZ95_RS03305	COG1970	mechanosensitive ion channel activity
RZ95_RS03315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RZ95_RS03325	COG3659	wide pore channel activity
RZ95_RS03330	COG1902	pentaerythritol trinitrate reductase activity
RZ95_RS03360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RZ95_RS03375	COG4456	Virulence-associated protein
RZ95_RS03380	COG1487	ribonuclease activity
RZ95_RS03410	COG0346	lactoylglutathione lyase activity
RZ95_RS03415	COG0564	pseudouridine synthase activity
RZ95_RS03435	COG3189	MarR family transcriptional regulator
RZ95_RS03440	COG2824	Alkylphosphonate utilization operon protein PhnA
RZ95_RS03450	COG3422	double-strand break repair
RZ95_RS03475	COG0488	(ABC) transporter
RZ95_RS03490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RZ95_RS03510	COG0730	response to heat
RZ95_RS03520	COG1196	nuclear chromosome segregation
RZ95_RS03525	COG3115	cell septum assembly
RZ95_RS03530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RZ95_RS03535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RZ95_RS03560	COG2193	ferroxidase activity
RZ95_RS03565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RZ95_RS03570	COG2267	carboxylic ester hydrolase activity
RZ95_RS03585	COG4106	trans-aconitate 2-methyltransferase activity
RZ95_RS03655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RZ95_RS03660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RZ95_RS03670	COG0009	L-threonylcarbamoyladenylate synthase
RZ95_RS03675	COG3101	peptidyl-lysine hydroxylation
RZ95_RS03680	COG1399	metal-binding, possibly nucleic acid-binding protein
RZ95_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS03705	COG1652	LysM domain
RZ95_RS03710	COG1802	Transcriptional regulator
RZ95_RS03715	COG0439	Biotin carboxylase
RZ95_RS03745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RZ95_RS03755	COG0745	RESPONSE REGULATOR receiver
RZ95_RS03760	COG2205	protein histidine kinase activity
RZ95_RS03770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RZ95_RS03790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RZ95_RS03805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RZ95_RS03815	COG0713	ATP synthesis coupled electron transport
RZ95_RS03820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RZ95_RS03825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RZ95_RS03840	COG1278	Cold shock
RZ95_RS03845	COG1278	Cold shock
RZ95_RS03850	COG0583	DNA-binding transcription factor activity
RZ95_RS03870	COG2852	Protein conserved in bacteria
RZ95_RS03885	COG0525	valine-tRNA ligase activity
RZ95_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS03915	COG2433	Pfam Transposase IS66
RZ95_RS03920	COG4372	Transposase
RZ95_RS03930	COG0393	Putative heavy-metal-binding
RZ95_RS03935	COG1538	Outer membrane efflux protein
RZ95_RS03945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RZ95_RS03950	COG0671	phosphoesterase, PA-phosphatase related
RZ95_RS03970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RZ95_RS03980	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RZ95_RS03990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RZ95_RS03995	COG1648	precorrin-2 dehydrogenase activity
RZ95_RS03995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RZ95_RS04000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RZ95_RS04020	COG0531	amino acid
RZ95_RS04035	COG0321	lipoyl(octanoyl) transferase activity
RZ95_RS04040	COG2921	Belongs to the UPF0250 family
RZ95_RS04060	COG1280	lysine exporter protein (LysE YggA)
RZ95_RS04075	COG0586	Pfam SNARE associated Golgi protein
RZ95_RS04100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RZ95_RS04125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RZ95_RS04130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RZ95_RS04160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RZ95_RS04175	COG0358	DNA primase activity
RZ95_RS04185	COG0564	pseudouridine synthase activity
RZ95_RS04210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RZ95_RS04225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RZ95_RS04225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RZ95_RS04245	COG2072	flavoprotein involved in K transport
RZ95_RS04255	COG2009	succinate dehydrogenase
RZ95_RS04260	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RZ95_RS04265	COG1053	succinate dehydrogenase
RZ95_RS04270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RZ95_RS04285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RZ95_RS04295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RZ95_RS04305	COG2268	Band 7 protein
RZ95_RS04310	COG1585	Membrane protein implicated in regulation of membrane protease activity
RZ95_RS04320	COG2354	Protein conserved in bacteria
RZ95_RS04325	COG2321	neutral zinc metallopeptidase
RZ95_RS04340	COG3695	enzyme binding
RZ95_RS04365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RZ95_RS04370	COG0505	Belongs to the CarA family
RZ95_RS04395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RZ95_RS04400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RZ95_RS04440	COG2851	Citrate transporter
RZ95_RS04445	COG1253	flavin adenine dinucleotide binding
RZ95_RS04475	COG2239	Acts as a magnesium transporter
RZ95_RS04490	COG0501	Belongs to the peptidase M48B family
RZ95_RS04495	COG0741	lytic transglycosylase activity
RZ95_RS04500	COG0037	tRNA processing
RZ95_RS04510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
RZ95_RS04515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RZ95_RS04535	COG0697	spore germination
RZ95_RS04545	COG1309	transcriptional regulator
RZ95_RS04560	COG1741	Belongs to the pirin family
RZ95_RS04580	COG3739	integral membrane protein
RZ95_RS04595	COG3706	GGDEF domain
RZ95_RS04605	COG0302	gtp cyclohydrolase
RZ95_RS04615	COG0134	indole-3-glycerol-phosphate synthase activity
RZ95_RS04620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RZ95_RS04625	COG0512	Glutamine amidotransferase of anthranilate synthase
RZ95_RS04630	COG0174	glutamine synthetase
RZ95_RS04640	COG3161	chorismate lyase activity
RZ95_RS04645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RZ95_RS04685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RZ95_RS04690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RZ95_RS04695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RZ95_RS04700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RZ95_RS04715	COG1115	amino acid carrier protein
RZ95_RS04720	COG1113	amino acid transport
RZ95_RS04730	COG0019	diaminopimelate decarboxylase activity
RZ95_RS04740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RZ95_RS04750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RZ95_RS04755	COG1522	sequence-specific DNA binding
RZ95_RS04760	COG1280	lysine exporter protein (LysE YggA)
RZ95_RS04795	COG0842	Transport permease protein
RZ95_RS04800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RZ95_RS04815	COG2175	clavaminate synthase activity
RZ95_RS04835	COG0052	Belongs to the universal ribosomal protein uS2 family
RZ95_RS04860	COG4372	Transposase
RZ95_RS04890	COG4372	Transposase
RZ95_RS04900	COG2951	lytic endotransglycosylase activity
RZ95_RS04920	COG0842	Transport permease protein
RZ95_RS04925	COG1131	(ABC) transporter
RZ95_RS04935	COG0303	'Molybdopterin
RZ95_RS04940	COG0521	Mo-molybdopterin cofactor biosynthetic process
RZ95_RS04940	COG0315	cyclic pyranopterin monophosphate synthase activity
RZ95_RS04945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RZ95_RS04950	COG0243	molybdopterin cofactor binding
RZ95_RS04955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RZ95_RS04965	COG0725	ABC transporter, periplasmic molybdate-binding protein
RZ95_RS04970	COG4149	molybdate abc transporter
RZ95_RS05000	COG2169	Transcriptional regulator
RZ95_RS05005	COG0235	Class ii aldolase
RZ95_RS05010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RZ95_RS05015	COG0697	spore germination
RZ95_RS05020	COG0475	glutathione-regulated potassium exporter activity
RZ95_RS05020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RZ95_RS05025	COG3706	GGDEF domain
RZ95_RS05065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RZ95_RS05085	COG3634	alkyl hydroperoxide reductase activity
RZ95_RS05090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RZ95_RS05095	COG0826	peptidase U32
RZ95_RS05150	COG1720	tRNA m6t6A37 methyltransferase activity
RZ95_RS05160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RZ95_RS05175	COG0642	Histidine kinase
RZ95_RS05180	COG0494	nUDIX hydrolase
RZ95_RS05190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RZ95_RS05195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RZ95_RS05200	COG3139	Protein of unknown function (DUF1315)
RZ95_RS05215	COG1301	dicarboxylic acid transport
RZ95_RS05225	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS05230	COG0693	protein deglycase activity
RZ95_RS05240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RZ95_RS05245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RZ95_RS05275	COG0415	Belongs to the DNA photolyase family
RZ95_RS05285	COG2252	PERMEase
RZ95_RS05290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RZ95_RS05300	COG3038	cytochrome b561
RZ95_RS05315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RZ95_RS05325	COG0527	aspartate kinase activity
RZ95_RS05335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RZ95_RS05350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RZ95_RS05355	COG1522	sequence-specific DNA binding
RZ95_RS05380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RZ95_RS05395	COG0667	Aldo Keto reductase
RZ95_RS05405	COG1765	OsmC-like protein
RZ95_RS05430	COG0540	Belongs to the ATCase OTCase family
RZ95_RS05450	COG2031	fatty acid transporter
RZ95_RS05455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RZ95_RS05470	COG4770	biotin carboxylase activity
RZ95_RS05480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RZ95_RS05485	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS05490	COG1309	transcriptional regulator
RZ95_RS05495	COG0318	PFAM AMP-dependent synthetase and ligase
RZ95_RS05525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RZ95_RS05535	COG0659	secondary active sulfate transmembrane transporter activity
RZ95_RS05540	COG0625	glutathione transferase activity
RZ95_RS05545	COG2249	NAD(P)H dehydrogenase (quinone) activity
RZ95_RS05570	COG2363	Small membrane protein
RZ95_RS05585	COG1278	Cold shock
RZ95_RS05590	COG0513	Belongs to the DEAD box helicase family
RZ95_RS05600	COG0778	Nitroreductase
RZ95_RS05625	COG0167	dihydroorotate dehydrogenase activity
RZ95_RS05655	COG4783	chaperone-mediated protein folding
RZ95_RS05660	COG1610	YqeY-like protein
RZ95_RS05690	COG2815	serine threonine protein kinase
RZ95_RS05690	COG0515	serine threonine protein kinase
RZ95_RS05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RZ95_RS05725	COG1643	Atp-dependent helicase
RZ95_RS05745	COG1116	anion transmembrane transporter activity
RZ95_RS05745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RZ95_RS05755	COG2223	nitrite transmembrane transporter activity
RZ95_RS05760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RZ95_RS05765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RZ95_RS05770	COG0243	molybdopterin cofactor binding
RZ95_RS05780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RZ95_RS05815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RZ95_RS05820	COG0406	alpha-ribazole phosphatase activity
RZ95_RS05830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RZ95_RS05830	COG0517	IMP dehydrogenase activity
RZ95_RS05835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RZ95_RS05845	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RZ95_RS05850	COG1137	ATPase activity
RZ95_RS05870	COG4122	O-methyltransferase activity
RZ95_RS05880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RZ95_RS05920	COG2011	ABC-type metal ion transport system permease component
RZ95_RS05925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RZ95_RS05935	COG0151	Belongs to the GarS family
RZ95_RS05940	COG0138	bifunctional purine biosynthesis protein purh
RZ95_RS05945	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
RZ95_RS05975	COG0445	tRNA wobble uridine modification
RZ95_RS05990	COG2308	Evidence 4 Homologs of previously reported genes of
RZ95_RS06000	COG1305	Transglutaminase-like
RZ95_RS06015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RZ95_RS06020	COG0305	Participates in initiation and elongation during chromosome replication
RZ95_RS06035	COG0360	Binds together with S18 to 16S ribosomal RNA
RZ95_RS06055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RZ95_RS06060	COG1845	cytochrome c oxidase, subunit III
RZ95_RS06065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RZ95_RS06070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RZ95_RS06100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RZ95_RS06115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RZ95_RS06120	COG2890	protein-(glutamine-N5) methyltransferase activity
RZ95_RS06125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RZ95_RS06130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RZ95_RS06160	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS06165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RZ95_RS06180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RZ95_RS06205	COG0729	surface antigen
RZ95_RS06250	COG0786	glutamate:sodium symporter activity
RZ95_RS06260	COG1113	amino acid transport
RZ95_RS06285	COG0024	Methionine aminopeptidase
RZ95_RS06290	COG0583	DNA-binding transcription factor activity
RZ95_RS06295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RZ95_RS06310	COG3852	Histidine kinase
RZ95_RS06330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RZ95_RS06335	COG0575	Belongs to the CDS family
RZ95_RS06350	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RZ95_RS06370	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RZ95_RS06380	COG2137	regulation of response to DNA damage stimulus
RZ95_RS06385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RZ95_RS06390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RZ95_RS06395	COG1011	Hydrolase
RZ95_RS06420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RZ95_RS06645	COG0702	epimerase
RZ95_RS06650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RZ95_RS06670	COG0446	pyridine nucleotide-disulphide oxidoreductase
RZ95_RS06670	COG1902	pentaerythritol trinitrate reductase activity
RZ95_RS06685	COG2814	Major facilitator Superfamily
RZ95_RS06690	COG0656	L-ascorbic acid biosynthetic process
RZ95_RS06705	COG0583	DNA-binding transcription factor activity
RZ95_RS06725	COG0148	phosphopyruvate hydratase activity
RZ95_RS06740	COG0772	Belongs to the SEDS family
RZ95_RS06755	COG0579	oxidoreductase
RZ95_RS06765	COG1012	belongs to the aldehyde dehydrogenase family
RZ95_RS06770	COG1309	transcriptional regulator
RZ95_RS06775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RZ95_RS06790	COG4890	Cyd operon protein YbgT
RZ95_RS06795	COG1294	oxidase, subunit
RZ95_RS06810	COG1585	Membrane protein implicated in regulation of membrane protease activity
RZ95_RS06820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RZ95_RS06840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RZ95_RS06845	COG0569	domain protein
RZ95_RS06855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RZ95_RS06860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RZ95_RS06895	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RZ95_RS06900	COG0542	response to heat
RZ95_RS06930	COG0372	Belongs to the citrate synthase family
RZ95_RS06940	COG2819	hydrolase of the alpha beta superfamily
RZ95_RS06945	COG0318	PFAM AMP-dependent synthetase and ligase
RZ95_RS06970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RZ95_RS06970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RZ95_RS06975	COG1254	Belongs to the acylphosphatase family
RZ95_RS06980	COG1047	Peptidyl-prolyl cis-trans
RZ95_RS06985	COG1252	NADH dehydrogenase
RZ95_RS06990	COG1686	Belongs to the peptidase S11 family
RZ95_RS07000	COG2351	hydroxyisourate hydrolase activity
RZ95_RS07045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RZ95_RS07050	COG1335	isochorismatase
RZ95_RS07070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RZ95_RS07085	COG2323	membrane
RZ95_RS07125	COG2223	nitrite transmembrane transporter activity
RZ95_RS07130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RZ95_RS07135	COG1877	trehalose-phosphatase activity
RZ95_RS07145	COG1570	exodeoxyribonuclease VII activity
RZ95_RS07170	COG2826	transposase and inactivated derivatives, IS30 family
RZ95_RS07175	COG0582	viral genome integration into host DNA
RZ95_RS07195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RZ95_RS07200	COG1823	symporter activity
RZ95_RS07210	COG0612	Peptidase, M16
RZ95_RS07245	COG0352	thiamine-phosphate diphosphorylase activity
RZ95_RS07265	COG3293	Transposase
RZ95_RS07310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RZ95_RS07315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RZ95_RS07330	COG0456	acetyltransferase
RZ95_RS07335	COG2353	YceI-like domain
RZ95_RS07340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RZ95_RS07340	COG0519	Catalyzes the synthesis of GMP from XMP
RZ95_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS07360	COG4302	ethanolamine ammonia-lyase activity
RZ95_RS07365	COG4303	Ethanolamine ammonia lyase large subunit
RZ95_RS07370	COG0531	amino acid
RZ95_RS07395	COG1454	alcohol dehydrogenase
RZ95_RS07405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RZ95_RS07410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RZ95_RS07415	COG2814	Major facilitator Superfamily
RZ95_RS07420	COG2707	UPF0756 membrane protein
RZ95_RS07425	COG1187	pseudouridine synthase activity
RZ95_RS07440	COG0564	pseudouridine synthase activity
RZ95_RS07445	COG0802	atpase or kinase
RZ95_RS07450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RZ95_RS07460	COG1923	regulation of RNA biosynthetic process
RZ95_RS07465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RZ95_RS07475	COG3178	'Phosphotransferase
RZ95_RS07480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RZ95_RS07490	COG1192	Involved in chromosome partitioning
RZ95_RS07495	COG1475	DNA binding
RZ95_RS07500	COG0811	peptide transport
RZ95_RS07510	COG1132	(ABC) transporter
RZ95_RS07515	COG1663	tetraacyldisaccharide 4'-kinase activity
RZ95_RS07535	COG0084	hydrolase, TatD family'
RZ95_RS07570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RZ95_RS07580	COG0590	tRNA wobble adenosine to inosine editing
RZ95_RS07600	COG0776	regulation of translation
RZ95_RS07615	COG2431	L-lysine efflux transmembrane transporter activity
RZ95_RS07630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RZ95_RS07635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RZ95_RS07655	COG1253	flavin adenine dinucleotide binding
RZ95_RS07680	COG0308	aminopeptidase N
RZ95_RS07690	COG0589	response to stress
RZ95_RS07705	COG2076	Multidrug Resistance protein
RZ95_RS07710	COG1309	transcriptional regulator
RZ95_RS07715	COG3135	benzoate transporter
RZ95_RS07725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RZ95_RS07730	COG0583	DNA-binding transcription factor activity
RZ95_RS07745	COG0183	Belongs to the thiolase family
RZ95_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS07770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RZ95_RS07775	COG0824	Thioesterase
RZ95_RS07780	COG1454	alcohol dehydrogenase
RZ95_RS07785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RZ95_RS07805	COG0069	glutamate synthase activity
RZ95_RS07810	COG2197	response regulator
RZ95_RS07820	COG2850	peptidyl-arginine hydroxylation
RZ95_RS07830	COG0424	maF-like protein
RZ95_RS07840	COG0126	phosphoglycerate kinase activity
RZ95_RS07855	COG0697	spore germination
RZ95_RS07875	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RZ95_RS07885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RZ95_RS07890	COG3781	membrane
RZ95_RS07935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RZ95_RS07945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RZ95_RS07975	COG0316	Belongs to the HesB IscA family
RZ95_RS07980	COG0822	iron-sulfur transferase activity
RZ95_RS07990	COG1959	2 iron, 2 sulfur cluster binding
RZ95_RS08005	COG0776	regulation of translation
RZ95_RS08010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RZ95_RS08035	COG0537	adenosine 5'-monophosphoramidase activity
RZ95_RS08070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RZ95_RS08085	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RZ95_RS08100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RZ95_RS08110	COG0133	tryptophan synthase activity
RZ95_RS08115	COG0517	IMP dehydrogenase activity
RZ95_RS08115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RZ95_RS08140	COG0612	Peptidase, M16
RZ95_RS08145	COG0552	protein localization to endoplasmic reticulum
RZ95_RS08195	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS08200	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS08245	COG2199	diguanylate cyclase activity
RZ95_RS08255	COG2814	Major facilitator Superfamily
RZ95_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS08285	COG0864	Transcriptional regulator
RZ95_RS08355	COG0596	Alpha beta hydrolase
RZ95_RS08395	COG3293	Transposase
RZ95_RS08505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RZ95_RS08510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RZ95_RS08570	COG2814	Major facilitator Superfamily
RZ95_RS08610	COG1253	flavin adenine dinucleotide binding
RZ95_RS08620	COG0604	alcohol dehydrogenase
RZ95_RS08625	COG1309	transcriptional regulator
RZ95_RS08680	COG1063	alcohol dehydrogenase
RZ95_RS08690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RZ95_RS08695	COG0508	dehydrogenase complex catalyzes the overall conversion of
RZ95_RS08700	COG0022	dehydrogenase e1 component
RZ95_RS08705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RZ95_RS08710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RZ95_RS08720	COG0745	RESPONSE REGULATOR receiver
RZ95_RS08725	COG5002	protein histidine kinase activity
RZ95_RS08735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RZ95_RS08740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RZ95_RS08750	COG0583	DNA-binding transcription factor activity
RZ95_RS08840	COG2814	Major facilitator Superfamily
RZ95_RS08845	COG0583	DNA-binding transcription factor activity
RZ95_RS08850	COG4948	Mandelate Racemase Muconate Lactonizing
RZ95_RS08855	COG4829	muconolactone delta-isomerase
RZ95_RS08865	COG4638	Rieske (2fe-2S)
RZ95_RS08870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
RZ95_RS08875	COG0543	2 iron, 2 sulfur cluster binding
RZ95_RS08875	COG0633	Ferredoxin
RZ95_RS08880	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS08885	COG3135	benzoate transporter
RZ95_RS08890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RZ95_RS08895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RZ95_RS08900	COG0183	Belongs to the thiolase family
RZ95_RS08905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RZ95_RS08920	COG0511	ligase activity, forming carbon-carbon bonds
RZ95_RS08935	COG0439	Biotin carboxylase
RZ95_RS08950	COG0583	DNA-binding transcription factor activity
RZ95_RS08955	COG0183	Belongs to the thiolase family
RZ95_RS08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RZ95_RS08975	COG2233	PERMEase
RZ95_RS08980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RZ95_RS08985	COG0251	oxidation-reduction process
RZ95_RS08990	COG1335	isochorismatase
RZ95_RS08995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RZ95_RS09000	COG0596	Alpha beta hydrolase
RZ95_RS09005	COG0640	Transcriptional regulator
RZ95_RS09025	COG3122	Protein conserved in bacteria
RZ95_RS09030	COG0668	transmembrane transport
RZ95_RS09040	COG1132	(ABC) transporter
RZ95_RS09065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RZ95_RS09070	COG3300	MHYT domain
RZ95_RS09070	COG5001	Diguanylate cyclase
RZ95_RS09085	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RZ95_RS09090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RZ95_RS09160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RZ95_RS09205	COG3293	Transposase
RZ95_RS09295	COG3561	AntA/AntB antirepressor
RZ95_RS09370	COG5410	chromosome segregation
RZ95_RS09385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RZ95_RS09545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RZ95_RS09550	COG0583	DNA-binding transcription factor activity
RZ95_RS09555	COG1380	Effector of murein hydrolase LrgA
RZ95_RS09560	COG1346	cytolysis
RZ95_RS09575	COG2223	nitrite transmembrane transporter activity
RZ95_RS09605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RZ95_RS09610	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RZ95_RS09615	COG2207	Transcriptional regulator
RZ95_RS09620	COG1944	ATP diphosphatase activity
RZ95_RS09625	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RZ95_RS09645	COG0730	response to heat
RZ95_RS09650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RZ95_RS09670	COG1546	Belongs to the CinA family
RZ95_RS09670	COG1058	Belongs to the CinA family
RZ95_RS09695	COG0204	Acyl-transferase
RZ95_RS09735	COG1464	Belongs to the NlpA lipoprotein family
RZ95_RS09745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RZ95_RS09750	COG2011	ABC-type metal ion transport system permease component
RZ95_RS09755	COG0012	GTP binding
RZ95_RS09780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RZ95_RS09795	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RZ95_RS09820	COG0386	Belongs to the glutathione peroxidase family
RZ95_RS09825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RZ95_RS09830	COG0436	Aminotransferase
RZ95_RS09850	COG3634	alkyl hydroperoxide reductase activity
RZ95_RS09875	COG2070	2-Nitropropane dioxygenase
RZ95_RS09885	COG3038	cytochrome b561
RZ95_RS09905	COG1278	Cold shock
RZ95_RS09915	COG0604	alcohol dehydrogenase
RZ95_RS09920	COG1733	regulation of RNA biosynthetic process
RZ95_RS09980	COG1309	transcriptional regulator
RZ95_RS10005	COG0842	Transport permease protein
RZ95_RS10010	COG0842	Transport permease protein
RZ95_RS10015	COG1131	(ABC) transporter
RZ95_RS10060	COG0697	spore germination
RZ95_RS10075	COG1538	Outer membrane efflux protein
RZ95_RS10080	COG0463	Glycosyl transferase, family 2
RZ95_RS10080	COG0457	Tetratricopeptide repeat
RZ95_RS10105	COG1126	abc transporter atp-binding protein
RZ95_RS10110	COG0765	amino acid transport
RZ95_RS10130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RZ95_RS10150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RZ95_RS10155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RZ95_RS10190	COG4695	Portal protein
RZ95_RS10405	COG0714	Associated with various cellular activities
RZ95_RS10415	COG2879	small protein
RZ95_RS10420	COG1966	Carbon starvation protein
RZ95_RS10425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RZ95_RS10430	COG1509	lysine 2,3-aminomutase activity
RZ95_RS10445	COG0254	rRNA binding
RZ95_RS10465	COG1067	ATP-dependent peptidase activity
RZ95_RS10470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RZ95_RS10475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RZ95_RS10480	COG0616	signal peptide processing
RZ95_RS10485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RZ95_RS10495	COG0573	inorganic phosphate transmembrane transporter activity
RZ95_RS10500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RZ95_RS10505	COG0076	glutamate decarboxylase activity
RZ95_RS10510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RZ95_RS10525	COG0671	phosphoesterase, PA-phosphatase related
RZ95_RS10530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RZ95_RS10540	COG1733	regulation of RNA biosynthetic process
RZ95_RS10545	COG0702	epimerase
RZ95_RS10575	COG0556	nucleotide-excision repair
RZ95_RS10590	COG2199	diguanylate cyclase activity
RZ95_RS10600	COG3293	Transposase
RZ95_RS10605	COG0436	Aminotransferase
RZ95_RS10640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RZ95_RS10645	COG1381	Involved in DNA repair and RecF pathway recombination
RZ95_RS10655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RZ95_RS10670	COG0681	Belongs to the peptidase S26 family
RZ95_RS10705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RZ95_RS10715	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RZ95_RS10730	COG4208	sulfate ABC transporter
RZ95_RS10735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RZ95_RS10740	COG0583	DNA-binding transcription factor activity
RZ95_RS10760	COG0602	queuosine metabolic process
RZ95_RS10765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RZ95_RS10780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RZ95_RS10790	COG0583	DNA-binding transcription factor activity
RZ95_RS10795	COG2353	YceI-like domain
RZ95_RS10800	COG1051	belongs to the nudix hydrolase family
RZ95_RS10800	COG1056	cytidyltransferase-related domain
RZ95_RS10805	COG1024	Enoyl-CoA hydratase
RZ95_RS10815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RZ95_RS10815	COG3323	Protein of unknown function (DUF1653)
RZ95_RS10825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RZ95_RS10825	COG0047	phosphoribosylformylglycinamidine synthase activity
RZ95_RS10845	COG0632	four-way junction helicase activity
RZ95_RS10850	COG2255	four-way junction helicase activity
RZ95_RS10865	COG0824	Thioesterase
RZ95_RS10885	COG0823	Involved in the tonB-independent uptake of proteins
RZ95_RS10905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RZ95_RS10935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RZ95_RS10940	COG0628	permease
RZ95_RS10945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RZ95_RS10950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RZ95_RS10970	COG0658	competence protein
RZ95_RS10970	COG2333	competence protein COMEC
RZ95_RS10975	COG1136	(ABC) transporter
RZ95_RS10995	COG1671	Belongs to the UPF0178 family
RZ95_RS11005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RZ95_RS11010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RZ95_RS11055	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RZ95_RS11060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RZ95_RS11065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RZ95_RS11070	COG5001	Diguanylate cyclase
RZ95_RS11070	COG1716	ATPase activity
RZ95_RS11075	COG0281	malic enzyme
RZ95_RS11075	COG0280	phosphate acetyltransferase
RZ95_RS11110	COG0446	pyridine nucleotide-disulphide oxidoreductase
RZ95_RS11110	COG1902	pentaerythritol trinitrate reductase activity
RZ95_RS11115	COG0277	FAD linked oxidase domain protein
RZ95_RS11125	COG2186	Transcriptional regulator
RZ95_RS11140	COG5001	Diguanylate cyclase
RZ95_RS11140	COG4251	negative regulation of phosphorylation
RZ95_RS11140	COG2203	Gaf domain
RZ95_RS11140	COG3706	GGDEF domain
RZ95_RS11145	COG0418	dihydroorotase activity
RZ95_RS11150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RZ95_RS11160	COG0833	amino acid
RZ95_RS11170	COG0833	amino acid
RZ95_RS11195	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
RZ95_RS11210	COG4172	Belongs to the ABC transporter superfamily
RZ95_RS11215	COG4239	(ABC) transporter, permease
RZ95_RS11220	COG4174	ABC transporter (Permease)
RZ95_RS11225	COG4166	transmembrane transport
RZ95_RS11230	COG1388	LysM domain
RZ95_RS11230	COG0741	lytic transglycosylase activity
RZ95_RS11235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RZ95_RS11245	COG2816	NAD+ diphosphatase activity
RZ95_RS11250	COG0657	acetylesterase activity
RZ95_RS11270	COG0583	DNA-binding transcription factor activity
RZ95_RS11275	COG1388	LysM domain
RZ95_RS11275	COG4942	peptidase
RZ95_RS11290	COG0753	catalase activity
RZ95_RS11320	COG1686	Belongs to the peptidase S11 family
RZ95_RS11325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RZ95_RS11340	COG2915	High frequency lysogenization protein hflD homolog
RZ95_RS11360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RZ95_RS11365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RZ95_RS11380	COG0006	proline dipeptidase activity
RZ95_RS11455	COG1785	Belongs to the alkaline phosphatase family
RZ95_RS11485	COG4770	biotin carboxylase activity
RZ95_RS11505	COG1914	H( )-stimulated, divalent metal cation uptake system
RZ95_RS11510	COG0583	DNA-binding transcription factor activity
RZ95_RS11515	COG2217	Heavy metal translocating P-type atpase
RZ95_RS11525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RZ95_RS11540	COG2234	aminopeptidase activity
RZ95_RS11550	COG3384	dioxygenase
RZ95_RS11560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RZ95_RS11565	COG2878	Part of a membrane complex involved in electron transport
RZ95_RS11570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RZ95_RS11595	COG0768	penicillin binding
RZ95_RS11600	COG0742	ribosomal rna small subunit methyltransferase
RZ95_RS11625	COG3119	arylsulfatase activity
RZ95_RS11630	COG0641	radical SAM
RZ95_RS11655	COG1597	lipid kinase activity
RZ95_RS11670	COG0477	Major facilitator Superfamily
RZ95_RS11685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RZ95_RS11710	COG4221	oxidoreductase activity
RZ95_RS11710	COG3321	synthase
RZ95_RS11710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RZ95_RS11710	COG0604	alcohol dehydrogenase
RZ95_RS11725	COG1695	Transcriptional regulator
RZ95_RS11770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RZ95_RS11775	COG1773	rubredoxin
RZ95_RS11780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RZ95_RS11790	COG0583	DNA-binding transcription factor activity
RZ95_RS11810	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RZ95_RS11815	COG4181	ATPase activity
RZ95_RS11840	COG4771	TonB-dependent receptor
RZ95_RS11860	COG0306	phosphate transporter
RZ95_RS11880	COG2852	Protein conserved in bacteria
RZ95_RS11890	COG2223	nitrite transmembrane transporter activity
RZ95_RS11895	COG2207	Transcriptional regulator
RZ95_RS11900	COG0242	peptide deformylase activity
RZ95_RS11905	COG0477	Major facilitator Superfamily
RZ95_RS11945	COG0456	acetyltransferase
RZ95_RS11960	COG4681	YaeQ
RZ95_RS11965	COG0523	cobalamin synthesis protein
RZ95_RS11980	COG1607	acyl-coa hydrolase
RZ95_RS11985	COG1752	Esterase of the alpha-beta hydrolase superfamily
RZ95_RS11995	COG1115	amino acid carrier protein
RZ95_RS12000	COG0786	glutamate:sodium symporter activity
RZ95_RS12025	COG2814	Major facilitator Superfamily
RZ95_RS12030	COG1289	transmembrane transporter activity
RZ95_RS12040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RZ95_RS12100	COG2832	Protein of unknown function (DUF454)
RZ95_RS12115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RZ95_RS12125	COG0643	Histidine kinase
RZ95_RS12125	COG2198	Histidine kinase
RZ95_RS12125	COG0784	Response regulator, receiver
RZ95_RS12130	COG0840	transmembrane signaling receptor activity
RZ95_RS12210	COG2358	TRAP transporter, solute receptor (TAXI family
RZ95_RS12225	COG0489	protein tyrosine kinase activity
RZ95_RS12250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RZ95_RS12250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RZ95_RS12285	COG4716	Myosin-crossreactive antigen
RZ95_RS12315	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RZ95_RS12320	COG2081	HI0933 family
RZ95_RS12330	COG0668	transmembrane transport
RZ95_RS12350	COG0765	amino acid transport
RZ95_RS12355	COG0765	amino acid transport
RZ95_RS12360	COG1126	abc transporter atp-binding protein
RZ95_RS12370	COG0004	ammonium transporteR
RZ95_RS12385	COG0642	Histidine kinase
RZ95_RS12390	COG0745	RESPONSE REGULATOR receiver
RZ95_RS12425	COG1752	Esterase of the alpha-beta hydrolase superfamily
RZ95_RS12440	COG0142	geranyltranstransferase activity
RZ95_RS12445	COG2828	Protein conserved in bacteria
RZ95_RS12450	COG1113	amino acid transport
RZ95_RS12465	COG1113	amino acid transport
RZ95_RS12470	COG1448	Aminotransferase
RZ95_RS12485	COG0625	glutathione transferase activity
RZ95_RS12495	COG2072	flavoprotein involved in K transport
RZ95_RS12500	COG0431	NADPH-dependent FMN reductase
RZ95_RS12505	COG0798	PFAM Bile acid sodium symporter
RZ95_RS12515	COG0640	Transcriptional regulator
RZ95_RS12560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RZ95_RS12570	COG0424	maF-like protein
RZ95_RS12575	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RZ95_RS12580	COG1792	Involved in formation and maintenance of cell shape
RZ95_RS12590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RZ95_RS12600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RZ95_RS12640	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RZ95_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS12655	COG2610	gluconate transmembrane transporter activity
RZ95_RS12660	COG0583	DNA-binding transcription factor activity
RZ95_RS12670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RZ95_RS12680	COG4772	TonB-dependent receptor
RZ95_RS12685	COG4993	Dehydrogenase
RZ95_RS12690	COG3659	wide pore channel activity
RZ95_RS12695	COG3420	alginic acid biosynthetic process
RZ95_RS12700	COG0710	3-dehydroquinate dehydratase activity
RZ95_RS12705	COG3485	protocatechuate 3,4-dioxygenase
RZ95_RS12710	COG3485	protocatechuate 3,4-dioxygenase
RZ95_RS12715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RZ95_RS12720	COG2271	Major facilitator Superfamily
RZ95_RS12725	COG0596	Alpha beta hydrolase
RZ95_RS12730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RZ95_RS12735	COG0183	Belongs to the thiolase family
RZ95_RS12740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RZ95_RS12745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RZ95_RS12750	COG1414	Transcriptional regulator
RZ95_RS12760	COG1113	amino acid transport
RZ95_RS12770	COG3724	N-succinylarginine dihydrolase activity
RZ95_RS12775	COG1012	belongs to the aldehyde dehydrogenase family
RZ95_RS12780	COG3138	arginine N-succinyltransferase
RZ95_RS12790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RZ95_RS12795	COG1522	sequence-specific DNA binding
RZ95_RS12810	COG1012	belongs to the aldehyde dehydrogenase family
RZ95_RS12815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RZ95_RS12825	COG1113	amino acid transport
RZ95_RS12840	COG1271	oxidase subunit
RZ95_RS12845	COG1294	oxidase, subunit
RZ95_RS12850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RZ95_RS12860	COG1346	cytolysis
RZ95_RS12875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RZ95_RS12885	COG1522	sequence-specific DNA binding
RZ95_RS12900	COG2814	Major facilitator Superfamily
RZ95_RS12930	COG2826	transposase and inactivated derivatives, IS30 family
RZ95_RS12965	COG2130	NADP-dependent
RZ95_RS12970	COG1309	transcriptional regulator
RZ95_RS12980	COG1902	pentaerythritol trinitrate reductase activity
RZ95_RS12990	COG1979	alcohol dehydrogenase
RZ95_RS13000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RZ95_RS13015	COG3321	synthase
RZ95_RS13015	COG0604	alcohol dehydrogenase
RZ95_RS13020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RZ95_RS13025	COG0583	DNA-binding transcription factor activity
RZ95_RS13030	COG4221	oxidoreductase activity
RZ95_RS13050	COG3177	Filamentation induced by cAMP protein fic
RZ95_RS13060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RZ95_RS13095	COG0642	Histidine kinase
RZ95_RS13110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RZ95_RS13135	COG2816	NAD+ diphosphatase activity
RZ95_RS13140	COG3046	protein related to deoxyribodipyrimidine photolyase
RZ95_RS13215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RZ95_RS13220	COG2814	Major facilitator Superfamily
RZ95_RS13225	COG1566	PFAM secretion protein HlyD family protein
RZ95_RS13230	COG2050	protein possibly involved in aromatic compounds catabolism
RZ95_RS13245	COG1090	epimerase
RZ95_RS13255	COG5001	Diguanylate cyclase
RZ95_RS13255	COG4251	negative regulation of phosphorylation
RZ95_RS13255	COG2203	Gaf domain
RZ95_RS13255	COG3706	GGDEF domain
RZ95_RS13260	COG0420	3'-5' exonuclease activity
RZ95_RS13290	COG0735	belongs to the Fur family
RZ95_RS13295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RZ95_RS13300	COG2914	Belongs to the UPF0125 (RnfH) family
RZ95_RS13315	COG2826	transposase and inactivated derivatives, IS30 family
RZ95_RS13320	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RZ95_RS13330	COG2826	transposase and inactivated derivatives, IS30 family
RZ95_RS13335	COG0121	glutamine amidotransferase
RZ95_RS13350	COG0756	dUTP diphosphatase activity
RZ95_RS13355	COG0210	DNA helicase
RZ95_RS13360	COG2885	chlorophyll binding
RZ95_RS13365	COG0204	Acyl-transferase
RZ95_RS13375	COG0850	regulation of cytokinetic process
RZ95_RS13385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RZ95_RS13400	COG0531	amino acid
RZ95_RS13400	COG1674	ftsk spoiiie
RZ95_RS13405	COG0492	ferredoxin-NADP+ reductase activity
RZ95_RS13410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RZ95_RS13420	COG0456	acetyltransferase
RZ95_RS13445	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RZ95_RS13460	COG1981	membrane
RZ95_RS13470	COG1113	amino acid transport
RZ95_RS13475	COG0251	oxidation-reduction process
RZ95_RS13505	COG0351	phosphomethylpyrimidine kinase
RZ95_RS13505	COG0352	thiamine-phosphate diphosphorylase activity
RZ95_RS13505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RZ95_RS13515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RZ95_RS13540	COG2132	Multicopper oxidase
RZ95_RS13550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RZ95_RS13585	COG1968	undecaprenyl-diphosphatase activity
RZ95_RS13590	COG1214	PFAM Peptidase M22, glycoprotease
RZ95_RS13595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RZ95_RS13600	COG0494	nUDIX hydrolase
RZ95_RS13650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RZ95_RS13660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RZ95_RS13685	COG0693	protein deglycase activity
RZ95_RS13705	COG2814	Major facilitator Superfamily
RZ95_RS13735	COG2853	Lipoprotein
RZ95_RS13740	COG2208	phosphoserine phosphatase activity
RZ95_RS13750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RZ95_RS13755	COG1764	response to oxidative stress
RZ95_RS13785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RZ95_RS13785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RZ95_RS13800	COG0037	tRNA processing
RZ95_RS13810	COG0248	Ppx GppA phosphatase
RZ95_RS13835	COG0072	phenylalanine-tRNA ligase activity
RZ95_RS13880	COG1238	metal cluster binding
RZ95_RS13895	COG0625	glutathione transferase activity
RZ95_RS13915	COG0318	PFAM AMP-dependent synthetase and ligase
RZ95_RS13920	COG3028	Belongs to the UPF0307 family
RZ95_RS13930	COG1660	Displays ATPase and GTPase activities
RZ95_RS13935	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RZ95_RS13945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RZ95_RS13950	COG0617	tRNA 3'-terminal CCA addition
RZ95_RS13955	COG1555	photosystem II stabilization
RZ95_RS13960	COG3956	TIGRFAM MazG family protein
RZ95_RS13970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RZ95_RS13985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RZ95_RS13990	COG5002	protein histidine kinase activity
RZ95_RS13990	COG2205	protein histidine kinase activity
RZ95_RS13990	COG0784	Response regulator, receiver
RZ95_RS13995	COG1024	Enoyl-CoA hydratase
RZ95_RS14000	COG2084	Dehydrogenase
RZ95_RS14005	COG3622	Belongs to the hyi family
RZ95_RS14020	COG0004	ammonium transporteR
RZ95_RS14045	COG2814	Major facilitator Superfamily
RZ95_RS14065	COG0174	glutamine synthetase
RZ95_RS14070	COG0745	RESPONSE REGULATOR receiver
RZ95_RS14075	COG2205	protein histidine kinase activity
RZ95_RS14085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RZ95_RS14090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RZ95_RS14120	COG1271	oxidase subunit
RZ95_RS14125	COG1294	oxidase, subunit
RZ95_RS14150	COG0492	ferredoxin-NADP+ reductase activity
RZ95_RS14155	COG0431	NADPH-dependent FMN reductase
RZ95_RS14160	COG0798	PFAM Bile acid sodium symporter
RZ95_RS14170	COG0640	Transcriptional regulator
RZ95_RS14200	COG4372	Transposase
RZ95_RS14255	COG2207	Transcriptional regulator
RZ95_RS14295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RZ95_RS14320	COG0084	hydrolase, TatD family'
RZ95_RS14335	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RZ95_RS14345	COG0793	Belongs to the peptidase S41A family
RZ95_RS14360	COG2267	carboxylic ester hydrolase activity
RZ95_RS14370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RZ95_RS14375	COG0857	belongs to the CobB CobQ family
RZ95_RS14375	COG0280	phosphate acetyltransferase
RZ95_RS14390	COG0697	spore germination
RZ95_RS14395	COG3708	Transcriptional regulator
RZ95_RS14395	COG2207	Transcriptional regulator
RZ95_RS14405	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RZ95_RS14405	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RZ95_RS14425	COG0740	serine-type endopeptidase activity
RZ95_RS14440	COG4771	TonB-dependent receptor
RZ95_RS14445	COG4774	siderophore transport
RZ95_RS14460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RZ95_RS14465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RZ95_RS14470	COG2813	Specifically methylates the guanine in position
RZ95_RS14470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RZ95_RS14580	COG0788	formyltetrahydrofolate deformylase activity
RZ95_RS14605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RZ95_RS14605	COG4651	solute:proton antiporter activity
RZ95_RS14630	COG0210	DNA helicase
RZ95_RS14635	COG1929	Belongs to the glycerate kinase type-1 family
RZ95_RS14680	COG2900	Belongs to the SlyX family
RZ95_RS14685	COG0488	(ABC) transporter
RZ95_RS14695	COG1560	Kdo2-lipid A biosynthetic process
RZ95_RS14750	COG0473	3-isopropylmalate dehydrogenase activity
RZ95_RS14765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RZ95_RS14775	COG0583	DNA-binding transcription factor activity
RZ95_RS14825	COG1960	acyl-CoA dehydrogenase activity
RZ95_RS14840	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RZ95_RS14855	COG0583	DNA-binding transcription factor activity
RZ95_RS14870	COG0564	pseudouridine synthase activity
RZ95_RS14875	COG1530	ribonuclease E activity
RZ95_RS14880	COG0318	PFAM AMP-dependent synthetase and ligase
RZ95_RS14905	COG1983	PspC domain protein
RZ95_RS14925	COG0751	glycine-tRNA ligase activity
RZ95_RS14930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RZ95_RS14965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RZ95_RS14980	COG2226	methyltransferase
RZ95_RS14995	COG0493	'glutamate synthase
RZ95_RS14995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RZ95_RS15005	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RZ95_RS15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RZ95_RS15020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RZ95_RS15030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RZ95_RS15040	COG0644	oxidoreductase
RZ95_RS15040	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RZ95_RS15050	COG0425	Belongs to the sulfur carrier protein TusA family
RZ95_RS15055	COG4535	Mg2 and Co2 transporter CorC
RZ95_RS15060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RZ95_RS15065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RZ95_RS15085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RZ95_RS15095	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RZ95_RS15115	COG2841	Protein conserved in bacteria
RZ95_RS15120	COG0598	Magnesium transport protein CorA
RZ95_RS15125	COG1185	polyribonucleotide nucleotidyltransferase activity
RZ95_RS15135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RZ95_RS15140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RZ95_RS15150	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RZ95_RS15180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RZ95_RS15195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RZ95_RS15205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RZ95_RS15210	COG2111	Na H antiporter
RZ95_RS15210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RZ95_RS15215	COG1006	Multisubunit Na H antiporter MnhC subunit
RZ95_RS15220	COG0651	ATP synthesis coupled electron transport
RZ95_RS15225	COG1863	multisubunit Na H antiporter MnhE subunit
RZ95_RS15230	COG2212	antiporter activity
RZ95_RS15235	COG1320	monovalent cation:proton antiporter activity
RZ95_RS15240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RZ95_RS15250	COG0195	Participates in both transcription termination and antitermination
RZ95_RS15310	COG0237	dephospho-CoA kinase activity
RZ95_RS15320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RZ95_RS15330	COG0497	DNA recombination
RZ95_RS15340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RZ95_RS15355	COG1289	transmembrane transporter activity
RZ95_RS15370	COG1132	(ABC) transporter
RZ95_RS15375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RZ95_RS15450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RZ95_RS15475	COG0326	Molecular chaperone. Has ATPase activity
RZ95_RS15485	COG3047	cAMP biosynthetic process
RZ95_RS15490	COG2056	Na+-H+ antiporter family
RZ95_RS15515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RZ95_RS15520	COG0085	RNA polymerase activity
RZ95_RS15525	COG0222	ribosome binding
RZ95_RS15530	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RZ95_RS15535	COG0081	regulation of translation
RZ95_RS15540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RZ95_RS15590	COG0546	phosphoglycolate phosphatase activity
RZ95_RS15620	COG0824	Thioesterase
RZ95_RS15640	COG0181	hydroxymethylbilane synthase activity
RZ95_RS15650	COG3275	phosphorelay sensor kinase activity
RZ95_RS15655	COG0165	Argininosuccinate lyase
RZ95_RS15670	COG1538	Outer membrane efflux protein
RZ95_RS15680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RZ95_RS15690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RZ95_RS15695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RZ95_RS15700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RZ95_RS15705	COG0772	Belongs to the SEDS family
RZ95_RS15710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RZ95_RS15730	COG4974	Belongs to the 'phage' integrase family
RZ95_RS15735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RZ95_RS15745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RZ95_RS15750	COG1686	Belongs to the peptidase S11 family
RZ95_RS15755	COG2197	response regulator
RZ95_RS15770	COG0793	Belongs to the peptidase S41A family
RZ95_RS15775	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RZ95_RS15780	COG0795	lipopolysaccharide-transporting ATPase activity
RZ95_RS15785	COG0795	lipopolysaccharide-transporting ATPase activity
RZ95_RS15805	COG0586	Pfam SNARE associated Golgi protein
RZ95_RS15820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RZ95_RS15820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RZ95_RS15830	COG0004	ammonium transporteR
RZ95_RS15835	COG0347	Belongs to the P(II) protein family
RZ95_RS15900	COG0640	Transcriptional regulator
RZ95_RS15955	COG0606	chelatase, subunit chli
RZ95_RS15980	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RZ95_RS15995	COG0318	PFAM AMP-dependent synthetase and ligase
RZ95_RS16010	COG0477	Major facilitator Superfamily
RZ95_RS16015	COG2860	membrane
RZ95_RS16020	COG3012	SEC-C Motif Domain Protein
RZ95_RS16025	COG1253	flavin adenine dinucleotide binding
RZ95_RS16055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RZ95_RS16130	COG0758	DNA mediated transformation
RZ95_RS16140	COG0697	spore germination
RZ95_RS16150	COG0386	Belongs to the glutathione peroxidase family
RZ95_RS16185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RZ95_RS16235	COG1121	(ABC) transporter
RZ95_RS16240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RZ95_RS16255	COG2837	iron assimilation
RZ95_RS16270	COG0791	NLP P60 protein
RZ95_RS16270	COG1388	LysM domain
RZ95_RS16280	COG0281	malic enzyme
RZ95_RS16330	COG0519	Catalyzes the synthesis of GMP from XMP
RZ95_RS16330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RZ95_RS16345	COG0586	Pfam SNARE associated Golgi protein
RZ95_RS16360	COG1192	Involved in chromosome partitioning
RZ95_RS16370	COG0271	Belongs to the BolA IbaG family
RZ95_RS16415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RZ95_RS16420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RZ95_RS16420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RZ95_RS16420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RZ95_RS16425	COG1105	Belongs to the carbohydrate kinase PfkB family
RZ95_RS16430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RZ95_RS16430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RZ95_RS16435	COG0583	DNA-binding transcription factor activity
RZ95_RS16440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RZ95_RS16455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RZ95_RS16465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RZ95_RS16470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RZ95_RS16480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RZ95_RS16485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RZ95_RS16495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RZ95_RS16510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RZ95_RS16515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RZ95_RS16525	COG0438	transferase activity, transferring glycosyl groups
RZ95_RS16535	COG0438	transferase activity, transferring glycosyl groups
RZ95_RS16560	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RZ95_RS16565	COG1088	dTDP-glucose 4,6-dehydratase activity
RZ95_RS16575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RZ95_RS16585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RZ95_RS16590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RZ95_RS16595	COG0438	transferase activity, transferring glycosyl groups
RZ95_RS16600	COG0438	transferase activity, transferring glycosyl groups
RZ95_RS16605	COG0438	transferase activity, transferring glycosyl groups
RZ95_RS16630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RZ95_RS16660	COG0728	peptidoglycan biosynthetic process
RZ95_RS16665	COG3023	N-Acetylmuramoyl-L-alanine amidase
RZ95_RS16675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RZ95_RS16685	COG3307	-O-antigen
RZ95_RS16690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RZ95_RS16695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RZ95_RS16700	COG0546	phosphoglycolate phosphatase activity
RZ95_RS16705	COG1028	Short-chain dehydrogenase reductase Sdr
RZ95_RS16725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RZ95_RS16725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RZ95_RS16730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RZ95_RS16735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RZ95_RS16740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RZ95_RS16745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RZ95_RS16750	COG1116	anion transmembrane transporter activity
RZ95_RS16755	COG1309	transcriptional regulator
RZ95_RS16770	COG0196	riboflavin kinase activity
RZ95_RS16775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RZ95_RS16780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RZ95_RS16785	COG1047	Peptidyl-prolyl cis-trans
RZ95_RS16805	COG2433	Pfam Transposase IS66
RZ95_RS16845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RZ95_RS16850	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RZ95_RS16855	COG2951	lytic endotransglycosylase activity
RZ95_RS16860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RZ95_RS16875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RZ95_RS16905	COG0861	Integral membrane protein TerC family
RZ95_RS16915	COG0754	glutathionylspermidine amidase activity
RZ95_RS16925	COG0402	S-adenosylhomocysteine deaminase activity
RZ95_RS16950	COG1230	cation diffusion facilitator family transporter
RZ95_RS16970	COG0706	membrane insertase activity
RZ95_RS16975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RZ95_RS17040	COG0488	(ABC) transporter
RZ95_RS17175	COG0733	neurotransmitter:sodium symporter activity
RZ95_RS17935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RZ95_RS17950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RZ95_RS18040	COG2826	transposase and inactivated derivatives, IS30 family
RZ95_RS18255	COG0450	alkyl hydroperoxide reductase
RZ95_RS18425	COG2183	response to ionizing radiation
RZ95_RS18480	COG0488	(ABC) transporter
RZ95_RS19230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RZ95_RS19455	COG0488	(ABC) transporter
RZ95_RS19555	COG0733	neurotransmitter:sodium symporter activity