locus-tag	class	description
CDG57_RS00035	COG1660	Displays ATPase and GTPase activities
CDG57_RS00045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG57_RS00055	COG2026	Addiction module toxin, RelE StbE family
CDG57_RS00100	COG3173	Aminoglycoside phosphotransferase
CDG57_RS00105	COG0488	(ABC) transporter
CDG57_RS00140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDG57_RS00150	COG2026	Addiction module toxin, RelE StbE family
CDG57_RS00175	COG1192	Involved in chromosome partitioning
CDG57_RS00250	COG0592	DNA-directed DNA polymerase activity
CDG57_RS00260	COG0187	DNA topoisomerase II activity
CDG57_RS00270	COG0586	Pfam SNARE associated Golgi protein
CDG57_RS00275	COG0488	(ABC) transporter
CDG57_RS00310	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG57_RS00315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG57_RS00360	COG1012	belongs to the aldehyde dehydrogenase family
CDG57_RS00365	COG0733	neurotransmitter:sodium symporter activity
CDG57_RS00400	COG0583	DNA-binding transcription factor activity
CDG57_RS00415	COG2233	PERMEase
CDG57_RS00425	COG1309	transcriptional regulator
CDG57_RS00430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_RS00460	COG2814	Major facilitator Superfamily
CDG57_RS00470	COG0583	DNA-binding transcription factor activity
CDG57_RS00480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG57_RS00485	COG1064	alcohol dehydrogenase
CDG57_RS00490	COG2818	Glycosylase
CDG57_RS00500	COG0739	heme binding
CDG57_RS00515	COG5487	UPF0391 membrane protein
CDG57_RS00520	COG2983	Belongs to the UPF0260 family
CDG57_RS00525	COG2133	pyrroloquinoline quinone binding
CDG57_RS00535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDG57_RS00555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDG57_RS00565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG57_RS00570	COG1335	isochorismatase
CDG57_RS00645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDG57_RS00695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG57_RS00705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDG57_RS00710	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDG57_RS00715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDG57_RS00735	COG3830	Belongs to the UPF0237 family
CDG57_RS00735	COG0560	Phosphoserine phosphatase
CDG57_RS00780	COG0583	DNA-binding transcription factor activity
CDG57_RS00815	COG0534	Mate efflux family protein
CDG57_RS00820	COG0436	Aminotransferase
CDG57_RS00830	COG2733	membrane
CDG57_RS00845	COG2918	glutathione biosynthetic process
CDG57_RS00865	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_RS00895	COG1324	tolerance protein
CDG57_RS00900	COG0673	inositol 2-dehydrogenase activity
CDG57_RS00920	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_RS00930	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_RS01005	COG3150	esterase
CDG57_RS01050	COG0456	acetyltransferase
CDG57_RS01100	COG1393	Belongs to the ArsC family
CDG57_RS01105	COG0708	Exodeoxyribonuclease III
CDG57_RS01135	COG0386	Belongs to the glutathione peroxidase family
CDG57_RS01140	COG0189	ligase activity
CDG57_RS01160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDG57_RS01170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG57_RS01210	COG2119	membrane
CDG57_RS01215	COG4774	siderophore transport
CDG57_RS01220	COG0426	domain, Protein
CDG57_RS01220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG57_RS01240	COG0259	pyridoxamine-phosphate oxidase activity
CDG57_RS01245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDG57_RS01270	COG1902	pentaerythritol trinitrate reductase activity
CDG57_RS01275	COG1519	Transferase
CDG57_RS01280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG57_RS01285	COG0668	transmembrane transport
CDG57_RS01295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG57_RS01300	COG1335	isochorismatase
CDG57_RS01345	COG1309	transcriptional regulator
CDG57_RS01350	COG3321	synthase
CDG57_RS01350	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_RS01350	COG0604	alcohol dehydrogenase
CDG57_RS01360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG57_RS01375	COG2814	Major facilitator Superfamily
CDG57_RS01380	COG0629	single-stranded DNA binding
CDG57_RS01395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG57_RS01400	COG1012	belongs to the aldehyde dehydrogenase family
CDG57_RS01410	COG1335	isochorismatase
CDG57_RS01420	COG3293	Transposase
CDG57_RS01425	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG57_RS01495	COG0582	viral genome integration into host DNA
CDG57_RS01540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDG57_RS01560	COG2329	Antibiotic biosynthesis monooxygenase
CDG57_RS01570	COG1396	sequence-specific DNA binding
CDG57_RS01575	COG0659	secondary active sulfate transmembrane transporter activity
CDG57_RS01595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG57_RS01625	COG0427	acetyl-CoA hydrolase
CDG57_RS01680	COG0477	Major facilitator Superfamily
CDG57_RS01685	COG0789	Transcriptional regulator
CDG57_RS01690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG57_RS01690	COG3320	Male sterility
CDG57_RS01695	COG4221	oxidoreductase activity
CDG57_RS01705	COG0488	(ABC) transporter
CDG57_RS01775	COG0833	amino acid
CDG57_RS01800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG57_RS01820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDG57_RS01825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG57_RS01835	COG2226	methyltransferase
CDG57_RS01885	COG0067	glutamate synthase
CDG57_RS01885	COG0069	glutamate synthase activity
CDG57_RS01885	COG0070	glutamate synthase
CDG57_RS01890	COG0493	'glutamate synthase
CDG57_RS01895	COG1704	LemA family
CDG57_RS01900	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDG57_RS01910	COG4969	Belongs to the N-Me-Phe pilin family
CDG57_RS01925	COG3307	-O-antigen
CDG57_RS01945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_RS01955	COG0194	GDP metabolic process
CDG57_RS01960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDG57_RS01965	COG4968	Prepilin-type N-terminal cleavage methylation domain
CDG57_RS02000	COG0228	four-way junction DNA binding
CDG57_RS02005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG57_RS02015	COG0335	large ribosomal subunit rRNA binding
CDG57_RS02020	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDG57_RS02025	COG5380	lipid catabolic process
CDG57_RS02030	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG57_RS02050	COG5006	permease, DMT superfamily
CDG57_RS02055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG57_RS02060	COG0277	FAD linked oxidase domain protein
CDG57_RS02075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CDG57_RS02080	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG57_RS02100	COG1289	transmembrane transporter activity
CDG57_RS02105	COG2032	superoxide dismutase activity
CDG57_RS02110	COG0628	permease
CDG57_RS02115	COG1192	Involved in chromosome partitioning
CDG57_RS02125	COG2226	methyltransferase
CDG57_RS02140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG57_RS02190	COG0471	metal ion transport
CDG57_RS02200	COG0517	IMP dehydrogenase activity
CDG57_RS02205	COG1983	PspC domain protein
CDG57_RS02215	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS02235	COG0408	coproporphyrinogen oxidase activity
CDG57_RS02255	COG0513	Belongs to the DEAD box helicase family
CDG57_RS02265	COG1127	ABC transporter
CDG57_RS02270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG57_RS02275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG57_RS02280	COG2854	intermembrane phospholipid transfer
CDG57_RS02300	COG0598	Magnesium transport protein CorA
CDG57_RS02310	COG0494	nUDIX hydrolase
CDG57_RS02315	COG1040	competence protein
CDG57_RS02320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDG57_RS02335	COG2937	Belongs to the GPAT DAPAT family
CDG57_RS02340	COG1946	Acyl-CoA thioesterase
CDG57_RS02345	COG1301	dicarboxylic acid transport
CDG57_RS02360	COG1959	2 iron, 2 sulfur cluster binding
CDG57_RS02370	COG0433	COG0433 Predicted ATPase
CDG57_RS02375	COG0626	cystathionine gamma-synthase activity
CDG57_RS02390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDG57_RS02410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG57_RS02435	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDG57_RS02460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG57_RS02475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG57_RS02540	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS02545	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDG57_RS02580	COG0697	spore germination
CDG57_RS02595	COG0339	signal peptide processing
CDG57_RS02605	COG0557	exoribonuclease II activity
CDG57_RS02645	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG57_RS02665	COG1295	ribonuclease BN
CDG57_RS02700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDG57_RS02725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_RS02725	COG2813	Specifically methylates the guanine in position
CDG57_RS02735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG57_RS02745	COG4774	siderophore transport
CDG57_RS02755	COG0740	serine-type endopeptidase activity
CDG57_RS02775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG57_RS02775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG57_RS02785	COG0697	spore germination
CDG57_RS02790	COG0857	belongs to the CobB CobQ family
CDG57_RS02790	COG0280	phosphate acetyltransferase
CDG57_RS02795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDG57_RS02805	COG2267	carboxylic ester hydrolase activity
CDG57_RS02820	COG0793	Belongs to the peptidase S41A family
CDG57_RS02845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG57_RS02855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG57_RS02860	COG1408	metallophosphoesterase
CDG57_RS02870	COG2199	diguanylate cyclase activity
CDG57_RS02925	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS02930	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS02940	COG1309	transcriptional regulator
CDG57_RS02955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG57_RS02960	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS03015	COG2969	positive regulation of protein catabolic process
CDG57_RS03020	COG0625	glutathione transferase activity
CDG57_RS03025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG57_RS03040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDG57_RS03045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG57_RS03050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG57_RS03130	COG1862	Preprotein translocase
CDG57_RS03150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDG57_RS03185	COG2205	protein histidine kinase activity
CDG57_RS03185	COG0784	Response regulator, receiver
CDG57_RS03190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG57_RS03200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDG57_RS03210	COG0438	transferase activity, transferring glycosyl groups
CDG57_RS03255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG57_RS03295	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS03300	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS03310	COG2205	protein histidine kinase activity
CDG57_RS03315	COG0745	RESPONSE REGULATOR receiver
CDG57_RS03330	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDG57_RS03350	COG2096	Adenosyltransferase
CDG57_RS03355	COG4206	TonB-dependent receptor
CDG57_RS03410	COG0285	dihydrofolate synthase activity
CDG57_RS03435	COG0450	alkyl hydroperoxide reductase
CDG57_RS03460	COG0477	Major facilitator Superfamily
CDG57_RS03465	COG1272	protein, Hemolysin III
CDG57_RS03495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG57_RS03495	COG1024	Enoyl-CoA hydratase
CDG57_RS03500	COG0183	Belongs to the thiolase family
CDG57_RS03515	COG2207	Transcriptional regulator
CDG57_RS03520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG57_RS03535	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_RS03555	COG0183	Belongs to the thiolase family
CDG57_RS03570	COG1690	Belongs to the RtcB family
CDG57_RS03575	COG0833	amino acid
CDG57_RS03585	COG2233	PERMEase
CDG57_RS03590	COG1217	gtp-binding protein TYPA
CDG57_RS03595	COG1970	mechanosensitive ion channel activity
CDG57_RS03605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG57_RS03625	COG0354	folic acid binding
CDG57_RS03635	COG3189	MarR family transcriptional regulator
CDG57_RS03640	COG2824	Alkylphosphonate utilization operon protein PhnA
CDG57_RS03645	COG3422	double-strand break repair
CDG57_RS03675	COG0840	transmembrane signaling receptor activity
CDG57_RS03680	COG2198	Histidine kinase
CDG57_RS03680	COG0643	Histidine kinase
CDG57_RS03680	COG2198	Histidine kinase
CDG57_RS03680	COG0643	Histidine kinase
CDG57_RS03695	COG5510	response to toxic substance
CDG57_RS03705	COG2832	Protein of unknown function (DUF454)
CDG57_RS03710	COG1376	ErfK ybiS ycfS ynhG family protein
CDG57_RS03755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDG57_RS03765	COG1289	transmembrane transporter activity
CDG57_RS03785	COG0786	glutamate:sodium symporter activity
CDG57_RS03790	COG1115	amino acid carrier protein
CDG57_RS03795	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG57_RS03800	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDG57_RS03845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG57_RS03855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG57_RS03860	COG1077	Cell shape determining protein MreB Mrl
CDG57_RS03865	COG1792	Involved in formation and maintenance of cell shape
CDG57_RS03875	COG0424	maF-like protein
CDG57_RS03880	COG1530	ribonuclease E activity
CDG57_RS03890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG57_RS03900	COG0560	Phosphoserine phosphatase
CDG57_RS03910	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG57_RS03935	COG2851	Citrate transporter
CDG57_RS03945	COG0671	phosphoesterase, PA-phosphatase related
CDG57_RS03950	COG0174	glutamine synthetase
CDG57_RS03965	COG1113	amino acid transport
CDG57_RS03975	COG0142	geranyltranstransferase activity
CDG57_RS03980	COG2814	Major facilitator Superfamily
CDG57_RS03995	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG57_RS04015	COG2194	sulfuric ester hydrolase activity
CDG57_RS04020	COG0745	RESPONSE REGULATOR receiver
CDG57_RS04025	COG0642	Histidine kinase
CDG57_RS04040	COG0004	ammonium transporteR
CDG57_RS04055	COG0525	valine-tRNA ligase activity
CDG57_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_RS04070	COG0393	Putative heavy-metal-binding
CDG57_RS04075	COG0393	Putative heavy-metal-binding
CDG57_RS04080	COG1538	Outer membrane efflux protein
CDG57_RS04090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_RS04095	COG0671	phosphoesterase, PA-phosphatase related
CDG57_RS04125	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_RS04130	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDG57_RS04145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG57_RS04145	COG1648	precorrin-2 dehydrogenase activity
CDG57_RS04150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG57_RS04155	COG1733	regulation of RNA biosynthetic process
CDG57_RS04165	COG0531	amino acid
CDG57_RS04180	COG0321	lipoyl(octanoyl) transferase activity
CDG57_RS04215	COG0500	methyltransferase
CDG57_RS04220	COG0586	Pfam SNARE associated Golgi protein
CDG57_RS04225	COG1054	Belongs to the UPF0176 family
CDG57_RS04255	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDG57_RS04260	COG1053	succinate dehydrogenase
CDG57_RS04265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG57_RS04280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG57_RS04295	COG2268	Band 7 protein
CDG57_RS04300	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG57_RS04310	COG2354	Protein conserved in bacteria
CDG57_RS04315	COG2321	neutral zinc metallopeptidase
CDG57_RS04330	COG0589	response to stress
CDG57_RS04350	COG0505	Belongs to the CarA family
CDG57_RS04375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG57_RS04380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG57_RS04385	COG2304	oxidoreductase activity
CDG57_RS04405	COG3201	nicotinamide mononucleotide transporter
CDG57_RS04410	COG0584	glycerophosphoryl diester phosphodiesterase
CDG57_RS04415	COG2194	sulfuric ester hydrolase activity
CDG57_RS04430	COG2239	Acts as a magnesium transporter
CDG57_RS04440	COG0501	Belongs to the peptidase M48B family
CDG57_RS04445	COG0741	lytic transglycosylase activity
CDG57_RS04460	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CDG57_RS04495	COG0071	Belongs to the small heat shock protein (HSP20) family
CDG57_RS04500	COG0542	response to heat
CDG57_RS04545	COG0501	Belongs to the peptidase M48B family
CDG57_RS04550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG57_RS04555	COG3293	Transposase
CDG57_RS04580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG57_RS04600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG57_RS04730	COG1301	dicarboxylic acid transport
CDG57_RS04740	COG0583	DNA-binding transcription factor activity
CDG57_RS04755	COG1607	acyl-coa hydrolase
CDG57_RS04765	COG0523	cobalamin synthesis protein
CDG57_RS04770	COG4681	YaeQ
CDG57_RS04785	COG0726	polysaccharide deacetylase
CDG57_RS04785	COG1649	PFAM Uncharacterised BCR, COG1649
CDG57_RS04790	COG1215	transferase activity, transferring glycosyl groups
CDG57_RS04810	COG3293	Transposase
CDG57_RS04850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG57_RS04865	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CDG57_RS04870	COG1597	lipid kinase activity
CDG57_RS04905	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDG57_RS04925	COG4771	TonB-dependent receptor
CDG57_RS04940	COG0288	reversible hydration of carbon dioxide
CDG57_RS04955	COG4181	ATPase activity
CDG57_RS04960	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDG57_RS04965	COG0457	Tetratricopeptide repeat
CDG57_RS04965	COG0705	Rhomboid family
CDG57_RS04980	COG2070	2-Nitropropane dioxygenase
CDG57_RS04985	COG1294	oxidase, subunit
CDG57_RS04990	COG1271	oxidase subunit
CDG57_RS05005	COG0415	Belongs to the DNA photolyase family
CDG57_RS05015	COG1252	NADH dehydrogenase
CDG57_RS05020	COG1686	Belongs to the peptidase S11 family
CDG57_RS05040	COG1187	pseudouridine synthase activity
CDG57_RS05055	COG0612	Peptidase, M16
CDG57_RS05085	COG0352	thiamine-phosphate diphosphorylase activity
CDG57_RS05095	COG0564	pseudouridine synthase activity
CDG57_RS05105	COG0783	Belongs to the Dps family
CDG57_RS05115	COG1309	transcriptional regulator
CDG57_RS05135	COG1309	transcriptional regulator
CDG57_RS05145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG57_RS05150	COG0076	glutamate decarboxylase activity
CDG57_RS05165	COG0573	inorganic phosphate transmembrane transporter activity
CDG57_RS05175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG57_RS05180	COG0616	signal peptide processing
CDG57_RS05205	COG0742	ribosomal rna small subunit methyltransferase
CDG57_RS05210	COG0768	penicillin binding
CDG57_RS05235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDG57_RS05240	COG2878	Part of a membrane complex involved in electron transport
CDG57_RS05245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG57_RS05255	COG3384	dioxygenase
CDG57_RS05270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG57_RS05295	COG3831	ATPase activity
CDG57_RS05300	COG0714	Associated with various cellular activities
CDG57_RS05310	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CDG57_RS05345	COG0006	proline dipeptidase activity
CDG57_RS05350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG57_RS05355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG57_RS05410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG57_RS05415	COG1388	LysM domain
CDG57_RS05415	COG0741	lytic transglycosylase activity
CDG57_RS05420	COG4166	transmembrane transport
CDG57_RS05425	COG4174	ABC transporter (Permease)
CDG57_RS05430	COG4239	(ABC) transporter, permease
CDG57_RS05435	COG4172	Belongs to the ABC transporter superfamily
CDG57_RS05455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG57_RS05465	COG4251	negative regulation of phosphorylation
CDG57_RS05465	COG3706	GGDEF domain
CDG57_RS05465	COG2203	Gaf domain
CDG57_RS05465	COG5001	Diguanylate cyclase
CDG57_RS05480	COG3739	integral membrane protein
CDG57_RS05500	COG0302	gtp cyclohydrolase
CDG57_RS05515	COG3293	Transposase
CDG57_RS05530	COG0633	Ferredoxin
CDG57_RS05530	COG3217	Mosc domain protein beta barrel domain protein
CDG57_RS05535	COG1823	symporter activity
CDG57_RS05540	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG57_RS05545	COG0174	glutamine synthetase
CDG57_RS05550	COG3161	chorismate lyase activity
CDG57_RS05555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG57_RS05590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG57_RS05595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG57_RS05600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG57_RS05610	COG2223	nitrite transmembrane transporter activity
CDG57_RS05620	COG0024	Methionine aminopeptidase
CDG57_RS05625	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG57_RS05640	COG0280	phosphate acetyltransferase
CDG57_RS05640	COG0281	malic enzyme
CDG57_RS05650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG57_RS05655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDG57_RS05660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG57_RS05685	COG2011	ABC-type metal ion transport system permease component
CDG57_RS05690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG57_RS05700	COG0151	Belongs to the GarS family
CDG57_RS05705	COG0138	bifunctional purine biosynthesis protein purh
CDG57_RS05710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG57_RS05775	COG2252	PERMEase
CDG57_RS05780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG57_RS05785	COG3038	cytochrome b561
CDG57_RS05800	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG57_RS05810	COG0527	aspartate kinase activity
CDG57_RS05820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDG57_RS05835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG57_RS05845	COG2308	Evidence 4 Homologs of previously reported genes of
CDG57_RS05855	COG1305	Transglutaminase-like
CDG57_RS05865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG57_RS05870	COG0305	Participates in initiation and elongation during chromosome replication
CDG57_RS05905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDG57_RS05910	COG1845	cytochrome c oxidase, subunit III
CDG57_RS05915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG57_RS05920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG57_RS05945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG57_RS05970	COG0564	pseudouridine synthase activity
CDG57_RS05980	COG0802	atpase or kinase
CDG57_RS05985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDG57_RS05995	COG1923	regulation of RNA biosynthetic process
CDG57_RS06000	COG0697	spore germination
CDG57_RS06005	COG0778	Nitroreductase
CDG57_RS06010	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_RS06020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG57_RS06030	COG0519	Catalyzes the synthesis of GMP from XMP
CDG57_RS06030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG57_RS06040	COG0531	amino acid
CDG57_RS06050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG57_RS06105	COG0308	aminopeptidase N
CDG57_RS06120	COG1714	RDD family
CDG57_RS06125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG57_RS06125	COG0475	glutathione-regulated potassium exporter activity
CDG57_RS06130	COG3135	benzoate transporter
CDG57_RS06140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG57_RS06155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDG57_RS06185	COG0316	Belongs to the HesB IscA family
CDG57_RS06190	COG0822	iron-sulfur transferase activity
CDG57_RS06220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG57_RS06235	COG2137	regulation of response to DNA damage stimulus
CDG57_RS06245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDG57_RS06250	COG1011	Hydrolase
CDG57_RS06270	COG0268	Binds directly to 16S ribosomal RNA
CDG57_RS06275	COG0702	epimerase
CDG57_RS06280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG57_RS06305	COG2030	dehydratase
CDG57_RS06310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG57_RS06330	COG0424	maF-like protein
CDG57_RS06355	COG0778	Nitroreductase
CDG57_RS06390	COG1286	toxin biosynthetic process
CDG57_RS06440	COG3634	alkyl hydroperoxide reductase activity
CDG57_RS06445	COG2267	carboxylic ester hydrolase activity
CDG57_RS06480	COG0436	Aminotransferase
CDG57_RS06490	COG0386	Belongs to the glutathione peroxidase family
CDG57_RS06540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG57_RS06555	COG0012	GTP binding
CDG57_RS06560	COG2011	ABC-type metal ion transport system permease component
CDG57_RS06565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG57_RS06570	COG1464	Belongs to the NlpA lipoprotein family
CDG57_RS06605	COG0204	Acyl-transferase
CDG57_RS06630	COG1560	Kdo2-lipid A biosynthetic process
CDG57_RS06695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG57_RS06745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG57_RS06750	COG0826	peptidase U32
CDG57_RS06765	COG4682	membrane
CDG57_RS06780	COG2808	Putative FMN-binding domain
CDG57_RS06795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG57_RS06805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG57_RS06830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDG57_RS06860	COG0729	surface antigen
CDG57_RS06890	COG0471	metal ion transport
CDG57_RS06895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG57_RS06910	COG3647	Membrane
CDG57_RS06915	COG2814	Major facilitator Superfamily
CDG57_RS06920	COG0583	DNA-binding transcription factor activity
CDG57_RS06930	COG3293	Transposase
CDG57_RS06955	COG1720	tRNA m6t6A37 methyltransferase activity
CDG57_RS06965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDG57_RS06980	COG0642	Histidine kinase
CDG57_RS06990	COG0494	nUDIX hydrolase
CDG57_RS07000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG57_RS07005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG57_RS07010	COG3139	Protein of unknown function (DUF1315)
CDG57_RS07045	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS07060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG57_RS07075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDG57_RS07080	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDG57_RS07100	COG1690	Belongs to the RtcB family
CDG57_RS07105	COG1234	tRNA 3'-trailer cleavage
CDG57_RS07115	COG4650	regulator
CDG57_RS07180	COG0513	Belongs to the DEAD box helicase family
CDG57_RS07190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG57_RS07200	COG3178	'Phosphotransferase
CDG57_RS07205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDG57_RS07215	COG1192	Involved in chromosome partitioning
CDG57_RS07220	COG1475	DNA binding
CDG57_RS07225	COG0811	peptide transport
CDG57_RS07235	COG1132	(ABC) transporter
CDG57_RS07240	COG1663	tetraacyldisaccharide 4'-kinase activity
CDG57_RS07260	COG0084	hydrolase, TatD family'
CDG57_RS07325	COG0776	regulation of translation
CDG57_RS07360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDG57_RS07365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG57_RS07400	COG0024	Methionine aminopeptidase
CDG57_RS07405	COG0583	DNA-binding transcription factor activity
CDG57_RS07410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_RS07420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG57_RS07425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG57_RS07430	COG0517	IMP dehydrogenase activity
CDG57_RS07430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG57_RS07455	COG0552	protein localization to endoplasmic reticulum
CDG57_RS07485	COG4890	Cyd operon protein YbgT
CDG57_RS07490	COG1294	oxidase, subunit
CDG57_RS07515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG57_RS07535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG57_RS07540	COG0569	domain protein
CDG57_RS07545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG57_RS07550	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDG57_RS07575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG57_RS07580	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG57_RS07585	COG0542	response to heat
CDG57_RS07595	COG0488	(ABC) transporter
CDG57_RS07605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG57_RS07610	COG2267	carboxylic ester hydrolase activity
CDG57_RS07620	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG57_RS07620	COG1902	pentaerythritol trinitrate reductase activity
CDG57_RS07660	COG0148	phosphopyruvate hydratase activity
CDG57_RS07665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CDG57_RS07710	COG1802	Transcriptional regulator
CDG57_RS07725	COG1063	alcohol dehydrogenase
CDG57_RS07755	COG1454	alcohol dehydrogenase
CDG57_RS07765	COG2814	Major facilitator Superfamily
CDG57_RS07770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_RS07775	COG0183	Belongs to the thiolase family
CDG57_RS07780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG57_RS07785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG57_RS07790	COG3135	benzoate transporter
CDG57_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_RS07800	COG0633	Ferredoxin
CDG57_RS07800	COG0543	2 iron, 2 sulfur cluster binding
CDG57_RS07805	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDG57_RS07810	COG4638	Rieske (2fe-2S)
CDG57_RS07820	COG4829	muconolactone delta-isomerase
CDG57_RS07825	COG4948	Mandelate Racemase Muconate Lactonizing
CDG57_RS07830	COG0583	DNA-binding transcription factor activity
CDG57_RS07840	COG1944	ATP diphosphatase activity
CDG57_RS07855	COG0583	DNA-binding transcription factor activity
CDG57_RS07865	COG4770	biotin carboxylase activity
CDG57_RS07870	COG1024	Enoyl-CoA hydratase
CDG57_RS07875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG57_RS07880	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS07885	COG1309	transcriptional regulator
CDG57_RS07890	COG0318	PFAM AMP-dependent synthetase and ligase
CDG57_RS07930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG57_RS07935	COG0730	response to heat
CDG57_RS08305	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG57_RS08315	COG3706	GGDEF domain
CDG57_RS08330	COG0133	tryptophan synthase activity
CDG57_RS08340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG57_RS08360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG57_RS08390	COG0537	adenosine 5'-monophosphoramidase activity
CDG57_RS08415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_RS08435	COG0730	response to heat
CDG57_RS08470	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDG57_RS08485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG57_RS08500	COG2223	nitrite transmembrane transporter activity
CDG57_RS08530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG57_RS08545	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS08550	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS08555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG57_RS08560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG57_RS08565	COG2207	Transcriptional regulator
CDG57_RS08570	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_RS08580	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_RS08605	COG0575	Belongs to the CDS family
CDG57_RS08610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG57_RS08615	COG0233	cytoplasmic translational termination
CDG57_RS08630	COG3852	Histidine kinase
CDG57_RS08635	COG2204	response regulator
CDG57_RS08710	COG0303	'Molybdopterin
CDG57_RS08715	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG57_RS08715	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDG57_RS08730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG57_RS08735	COG0243	molybdopterin cofactor binding
CDG57_RS08750	COG0243	molybdopterin cofactor binding
CDG57_RS08755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_RS08760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_RS08760	COG2146	nitrite reductase [NAD(P)H] activity
CDG57_RS08765	COG2223	nitrite transmembrane transporter activity
CDG57_RS08775	COG1116	anion transmembrane transporter activity
CDG57_RS08775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG57_RS08805	COG2814	Major facilitator Superfamily
CDG57_RS08810	COG1113	amino acid transport
CDG57_RS08820	COG0625	glutathione transferase activity
CDG57_RS08840	COG0069	glutamate synthase activity
CDG57_RS08875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG57_RS08880	COG1454	alcohol dehydrogenase
CDG57_RS08885	COG0824	Thioesterase
CDG57_RS08890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDG57_RS08895	COG2850	peptidyl-arginine hydroxylation
CDG57_RS08930	COG3122	Protein conserved in bacteria
CDG57_RS08935	COG0668	transmembrane transport
CDG57_RS08950	COG1132	(ABC) transporter
CDG57_RS08970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG57_RS08980	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG57_RS08980	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG57_RS08980	COG0506	proline dehydrogenase activity
CDG57_RS08985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG57_RS08995	COG3698	Phosphodiester glycosidase
CDG57_RS09010	COG3811	Belongs to the UPF0386 family
CDG57_RS09020	COG2353	YceI-like domain
CDG57_RS09030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDG57_RS09035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG57_RS09075	COG1278	Cold shock
CDG57_RS09095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDG57_RS09095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDG57_RS09120	COG3539	Fimbrial protein
CDG57_RS09140	COG1309	transcriptional regulator
CDG57_RS09155	COG1979	alcohol dehydrogenase
CDG57_RS09165	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDG57_RS09180	COG3321	synthase
CDG57_RS09180	COG0604	alcohol dehydrogenase
CDG57_RS09185	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG57_RS09190	COG0583	DNA-binding transcription factor activity
CDG57_RS09195	COG4221	oxidoreductase activity
CDG57_RS09225	COG0277	FAD linked oxidase domain protein
CDG57_RS09235	COG2186	Transcriptional regulator
CDG57_RS09245	COG3177	Filamentation induced by cAMP protein fic
CDG57_RS09285	COG1131	(ABC) transporter
CDG57_RS09290	COG0842	Transport permease protein
CDG57_RS09305	COG0772	Belongs to the SEDS family
CDG57_RS09310	COG2951	lytic endotransglycosylase activity
CDG57_RS09330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG57_RS09335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG57_RS09355	COG1643	Atp-dependent helicase
CDG57_RS09375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG57_RS09395	COG3634	alkyl hydroperoxide reductase activity
CDG57_RS09415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG57_RS09465	COG1765	OsmC-like protein
CDG57_RS09475	COG0501	Belongs to the peptidase M48B family
CDG57_RS09480	COG4770	biotin carboxylase activity
CDG57_RS09485	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDG57_RS09490	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDG57_RS09495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDG57_RS09500	COG2072	flavoprotein involved in K transport
CDG57_RS09520	COG1309	transcriptional regulator
CDG57_RS09560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG57_RS09565	COG0010	Belongs to the arginase family
CDG57_RS09595	COG2188	Transcriptional regulator
CDG57_RS09625	COG1116	anion transmembrane transporter activity
CDG57_RS09630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG57_RS09660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG57_RS09670	COG3293	Transposase
CDG57_RS09680	COG2351	hydroxyisourate hydrolase activity
CDG57_RS09705	COG0745	RESPONSE REGULATOR receiver
CDG57_RS09710	COG0642	Histidine kinase
CDG57_RS09715	COG4106	trans-aconitate 2-methyltransferase activity
CDG57_RS09725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDG57_RS09765	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS09790	COG3293	Transposase
CDG57_RS09810	COG3293	Transposase
CDG57_RS09825	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG57_RS09850	COG2132	Multicopper oxidase
CDG57_RS09865	COG2205	protein histidine kinase activity
CDG57_RS09870	COG2217	Heavy metal translocating P-type atpase
CDG57_RS09910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDG57_RS09920	COG2184	nucleotidyltransferase activity
CDG57_RS09985	COG0789	Transcriptional regulator
CDG57_RS10040	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG57_RS10040	COG1902	pentaerythritol trinitrate reductase activity
CDG57_RS10050	COG1741	Belongs to the pirin family
CDG57_RS10120	COG0714	Associated with various cellular activities
CDG57_RS10125	COG2879	small protein
CDG57_RS10130	COG1966	Carbon starvation protein
CDG57_RS10135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG57_RS10140	COG1509	lysine 2,3-aminomutase activity
CDG57_RS10180	COG1067	ATP-dependent peptidase activity
CDG57_RS10185	COG0583	DNA-binding transcription factor activity
CDG57_RS10210	COG1686	Belongs to the peptidase S11 family
CDG57_RS10215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG57_RS10230	COG0482	sulfurtransferase activity
CDG57_RS10275	COG0028	Belongs to the TPP enzyme family
CDG57_RS10290	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_RS10310	COG1414	Transcriptional regulator
CDG57_RS10335	COG0515	serine threonine protein kinase
CDG57_RS10335	COG2815	serine threonine protein kinase
CDG57_RS10355	COG0697	spore germination
CDG57_RS10375	COG1610	YqeY-like protein
CDG57_RS10390	COG4783	chaperone-mediated protein folding
CDG57_RS10425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG57_RS10430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG57_RS10445	COG2351	hydroxyisourate hydrolase activity
CDG57_RS10460	COG5002	protein histidine kinase activity
CDG57_RS10480	COG0772	Belongs to the SEDS family
CDG57_RS10485	COG1253	flavin adenine dinucleotide binding
CDG57_RS10495	COG3842	ATPase activity
CDG57_RS10500	COG1840	ABC-type Fe3 transport system, periplasmic component
CDG57_RS10515	COG3293	Transposase
CDG57_RS10525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDG57_RS10575	COG1137	ATPase activity
CDG57_RS10580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDG57_RS10590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDG57_RS10595	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG57_RS10595	COG0517	IMP dehydrogenase activity
CDG57_RS10630	COG1253	flavin adenine dinucleotide binding
CDG57_RS10635	COG0222	ribosome binding
CDG57_RS10650	COG0175	sulfate reduction
CDG57_RS10660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDG57_RS10670	COG1773	rubredoxin
CDG57_RS10675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_RS10680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_RS10685	COG0583	DNA-binding transcription factor activity
CDG57_RS10745	COG0556	nucleotide-excision repair
CDG57_RS10770	COG0436	Aminotransferase
CDG57_RS10790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDG57_RS10805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG57_RS10810	COG0571	ribonuclease III activity
CDG57_RS10825	COG0481	GTPase activity
CDG57_RS10835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG57_RS10850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDG57_RS10855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDG57_RS10860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG57_RS10870	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDG57_RS10875	COG4208	sulfate ABC transporter
CDG57_RS10880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDG57_RS10885	COG0583	DNA-binding transcription factor activity
CDG57_RS10900	COG0602	queuosine metabolic process
CDG57_RS10905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDG57_RS10920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG57_RS10940	COG1942	4-Oxalocrotonate Tautomerase
CDG57_RS10945	COG0625	glutathione transferase activity
CDG57_RS10955	COG1051	belongs to the nudix hydrolase family
CDG57_RS10955	COG1056	cytidyltransferase-related domain
CDG57_RS10960	COG1024	Enoyl-CoA hydratase
CDG57_RS10965	COG0778	Nitroreductase
CDG57_RS10970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG57_RS10970	COG3323	Protein of unknown function (DUF1653)
CDG57_RS10980	COG2814	Major facilitator Superfamily
CDG57_RS10985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG57_RS10985	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG57_RS11010	COG0824	Thioesterase
CDG57_RS11030	COG0823	Involved in the tonB-independent uptake of proteins
CDG57_RS11050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG57_RS11085	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_RS11105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG57_RS11110	COG0628	permease
CDG57_RS11120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDG57_RS11130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG57_RS11130	COG0616	signal peptide processing
CDG57_RS11140	COG2333	competence protein COMEC
CDG57_RS11140	COG0658	competence protein
CDG57_RS11145	COG1136	(ABC) transporter
CDG57_RS11150	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDG57_RS11165	COG1671	Belongs to the UPF0178 family
CDG57_RS11185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_RS11205	COG2318	DinB family
CDG57_RS11225	COG1280	lysine exporter protein (LysE YggA)
CDG57_RS11235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDG57_RS11240	COG0019	diaminopimelate decarboxylase activity
CDG57_RS11250	COG1113	amino acid transport
CDG57_RS11255	COG1115	amino acid carrier protein
CDG57_RS11275	COG0306	phosphate transporter
CDG57_RS11285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_RS11295	COG0242	peptide deformylase activity
CDG57_RS11315	COG0589	response to stress
CDG57_RS11320	COG2175	clavaminate synthase activity
CDG57_RS11325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG57_RS11340	COG4521	taurine ABC transporter
CDG57_RS11350	COG1230	cation diffusion facilitator family transporter
CDG57_RS11365	COG4149	molybdate abc transporter
CDG57_RS11370	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDG57_RS11395	COG3040	lipid binding
CDG57_RS11400	COG0833	amino acid
CDG57_RS11415	COG1012	belongs to the aldehyde dehydrogenase family
CDG57_RS11425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG57_RS11430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG57_RS11465	COG0582	viral genome integration into host DNA
CDG57_RS11505	COG0629	single-stranded DNA binding
CDG57_RS11510	COG2217	Heavy metal translocating P-type atpase
CDG57_RS11515	COG0789	Transcriptional regulator
CDG57_RS11525	COG2814	Major facilitator Superfamily
CDG57_RS11530	COG1566	PFAM secretion protein HlyD family protein
CDG57_RS11545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG57_RS11550	COG1090	epimerase
CDG57_RS11600	COG0420	3'-5' exonuclease activity
CDG57_RS11630	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG57_RS11650	COG0121	glutamine amidotransferase
CDG57_RS11665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG57_RS11670	COG0756	dUTP diphosphatase activity
CDG57_RS11675	COG0210	DNA helicase
CDG57_RS11680	COG2885	chlorophyll binding
CDG57_RS11685	COG0204	Acyl-transferase
CDG57_RS11695	COG0850	regulation of cytokinetic process
CDG57_RS11705	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDG57_RS11715	COG1280	lysine exporter protein (LysE YggA)
CDG57_RS11720	COG1674	ftsk spoiiie
CDG57_RS11725	COG0492	ferredoxin-NADP+ reductase activity
CDG57_RS11730	COG0500	methyltransferase
CDG57_RS11735	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG57_RS11745	COG0456	acetyltransferase
CDG57_RS11760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDG57_RS11770	COG0049	tRNA binding
CDG57_RS11790	COG1981	membrane
CDG57_RS11800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG57_RS11800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG57_RS11825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG57_RS11870	COG0564	pseudouridine synthase activity
CDG57_RS11895	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDG57_RS11925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDG57_RS11950	COG3293	Transposase
CDG57_RS11970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG57_RS11980	COG0352	thiamine-phosphate diphosphorylase activity
CDG57_RS11980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG57_RS11980	COG0351	phosphomethylpyrimidine kinase
CDG57_RS11985	COG1652	LysM domain
CDG57_RS12005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDG57_RS12010	COG1399	metal-binding, possibly nucleic acid-binding protein
CDG57_RS12015	COG3101	peptidyl-lysine hydroxylation
CDG57_RS12020	COG0009	L-threonylcarbamoyladenylate synthase
CDG57_RS12035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG57_RS12040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG57_RS12050	COG4172	Belongs to the ABC transporter superfamily
CDG57_RS12075	COG4166	transmembrane transport
CDG57_RS12120	COG4106	trans-aconitate 2-methyltransferase activity
CDG57_RS12135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_RS12135	COG2226	methyltransferase
CDG57_RS12135	COG0596	Alpha beta hydrolase
CDG57_RS12145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG57_RS12165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG57_RS12175	COG1196	nuclear chromosome segregation
CDG57_RS12185	COG0730	response to heat
CDG57_RS12205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDG57_RS12215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG57_RS12220	COG4636	protein conserved in cyanobacteria
CDG57_RS12270	COG0489	protein tyrosine kinase activity
CDG57_RS12295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG57_RS12295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG57_RS12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG57_RS12335	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CDG57_RS12345	COG2081	HI0933 family
CDG57_RS12355	COG0668	transmembrane transport
CDG57_RS12370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG57_RS12375	COG0583	DNA-binding transcription factor activity
CDG57_RS12380	COG1278	Cold shock
CDG57_RS12405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_RS12410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG57_RS12425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_RS12440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDG57_RS12450	COG0649	NAD binding
CDG57_RS12450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_RS12460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_RS12465	COG3706	GGDEF domain
CDG57_RS12475	COG2205	protein histidine kinase activity
CDG57_RS12480	COG0745	RESPONSE REGULATOR receiver
CDG57_RS12500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG57_RS12505	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CDG57_RS12620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG57_RS12625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG57_RS12655	COG2132	Multicopper oxidase
CDG57_RS12665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDG57_RS12690	COG1968	undecaprenyl-diphosphatase activity
CDG57_RS12730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG57_RS12735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG57_RS12740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDG57_RS12800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG57_RS12810	COG1764	response to oxidative stress
CDG57_RS12835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG57_RS12835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG57_RS12850	COG0037	tRNA processing
CDG57_RS12860	COG0248	Ppx GppA phosphatase
CDG57_RS12885	COG0072	phenylalanine-tRNA ligase activity
CDG57_RS12920	COG1238	metal cluster binding
CDG57_RS12930	COG0625	glutathione transferase activity
CDG57_RS12950	COG0318	PFAM AMP-dependent synthetase and ligase
CDG57_RS12955	COG3028	Belongs to the UPF0307 family
CDG57_RS12980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDG57_RS12985	COG0617	tRNA 3'-terminal CCA addition
CDG57_RS12990	COG1555	photosystem II stabilization
CDG57_RS12995	COG3956	TIGRFAM MazG family protein
CDG57_RS13005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_RS13025	COG2205	protein histidine kinase activity
CDG57_RS13025	COG5002	protein histidine kinase activity
CDG57_RS13025	COG0784	Response regulator, receiver
CDG57_RS13030	COG1024	Enoyl-CoA hydratase
CDG57_RS13035	COG2084	Dehydrogenase
CDG57_RS13040	COG3622	Belongs to the hyi family
CDG57_RS13055	COG0004	ammonium transporteR
CDG57_RS13060	COG0300	oxidoreductase activity
CDG57_RS13090	COG2814	Major facilitator Superfamily
CDG57_RS13115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG57_RS13120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG57_RS13130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG57_RS13170	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDG57_RS13180	COG0732	type I restriction modification DNA specificity domain
CDG57_RS13190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDG57_RS13210	COG0174	glutamine synthetase
CDG57_RS13225	COG0745	RESPONSE REGULATOR receiver
CDG57_RS13230	COG2205	protein histidine kinase activity
CDG57_RS13240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDG57_RS13245	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG57_RS13325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG57_RS13335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDG57_RS13350	COG0084	hydrolase, TatD family'
CDG57_RS13355	COG0726	polysaccharide deacetylase
CDG57_RS13365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG57_RS13380	COG0431	NADPH-dependent FMN reductase
CDG57_RS13385	COG0798	PFAM Bile acid sodium symporter
CDG57_RS13395	COG0640	Transcriptional regulator
CDG57_RS13405	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDG57_RS13420	COG0440	acetolactate synthase activity
CDG57_RS13425	COG0028	Belongs to the TPP enzyme family
CDG57_RS13445	COG1466	dna polymerase III delta subunit
CDG57_RS13450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDG57_RS13455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_RS13460	COG1136	(ABC) transporter
CDG57_RS13460	COG0577	efflux transmembrane transporter activity
CDG57_RS13465	COG1538	Outer membrane efflux protein
CDG57_RS13490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG57_RS13495	COG1162	GTPase activity
CDG57_RS13530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDG57_RS13535	COG2003	Belongs to the UPF0758 family
CDG57_RS13540	COG3781	membrane
CDG57_RS13545	COG0613	PHP domain protein
CDG57_RS13555	COG2350	Protein conserved in bacteria
CDG57_RS13575	COG1666	GTP binding
CDG57_RS13590	COG1956	GAF domain-containing protein
CDG57_RS13595	COG1607	acyl-coa hydrolase
CDG57_RS13650	COG1183	phosphatidylcholine synthase activity
CDG57_RS13655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDG57_RS13685	COG0739	heme binding
CDG57_RS13685	COG0741	lytic transglycosylase activity
CDG57_RS13685	COG1196	nuclear chromosome segregation
CDG57_RS13695	COG1702	phosphate starvation-inducible protein PhoH
CDG57_RS13710	COG4773	Receptor
CDG57_RS13780	COG0788	formyltetrahydrofolate deformylase activity
CDG57_RS13805	COG4651	solute:proton antiporter activity
CDG57_RS13805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG57_RS13830	COG0724	RNA recognition motif
CDG57_RS13835	COG0210	DNA helicase
CDG57_RS13870	COG2900	Belongs to the SlyX family
CDG57_RS13875	COG0488	(ABC) transporter
CDG57_RS13885	COG1560	Kdo2-lipid A biosynthetic process
CDG57_RS13940	COG0473	3-isopropylmalate dehydrogenase activity
CDG57_RS13965	COG0583	DNA-binding transcription factor activity
CDG57_RS13990	COG0494	nUDIX hydrolase
CDG57_RS14000	COG0753	catalase activity
CDG57_RS14010	COG0583	DNA-binding transcription factor activity
CDG57_RS14045	COG1530	ribonuclease E activity
CDG57_RS14070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG57_RS14080	COG0534	Mate efflux family protein
CDG57_RS14085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG57_RS14130	COG0493	'glutamate synthase
CDG57_RS14130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG57_RS14140	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDG57_RS14145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG57_RS14160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG57_RS14170	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CDG57_RS14170	COG0644	oxidoreductase
CDG57_RS14180	COG1595	DNA-templated transcription, initiation
CDG57_RS14195	COG3220	belongs to the UPF0276 family
CDG57_RS14210	COG1279	arginine transmembrane transporter activity
CDG57_RS14215	COG0425	Belongs to the sulfur carrier protein TusA family
CDG57_RS14220	COG4535	Mg2 and Co2 transporter CorC
CDG57_RS14245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDG57_RS14255	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDG57_RS14270	COG0789	Transcriptional regulator
CDG57_RS14275	COG0598	Magnesium transport protein CorA
CDG57_RS14280	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG57_RS14285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDG57_RS14290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG57_RS14295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG57_RS14300	COG1074	ATP-dependent DNA helicase activity
CDG57_RS14305	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDG57_RS14330	COG2226	methyltransferase
CDG57_RS14340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG57_RS14355	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG57_RS14370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG57_RS14370	COG2111	Na H antiporter
CDG57_RS14375	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG57_RS14380	COG0651	ATP synthesis coupled electron transport
CDG57_RS14385	COG1863	multisubunit Na H antiporter MnhE subunit
CDG57_RS14390	COG2212	antiporter activity
CDG57_RS14395	COG1320	monovalent cation:proton antiporter activity
CDG57_RS14400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG57_RS14410	COG0195	Participates in both transcription termination and antitermination
CDG57_RS14460	COG0237	dephospho-CoA kinase activity
CDG57_RS14470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG57_RS14480	COG0497	DNA recombination
CDG57_RS14490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDG57_RS14515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDG57_RS14545	COG3706	GGDEF domain
CDG57_RS14575	COG1132	(ABC) transporter
CDG57_RS14585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG57_RS14605	COG0326	Molecular chaperone. Has ATPase activity
CDG57_RS14620	COG2056	Na+-H+ antiporter family
CDG57_RS14665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDG57_RS14685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDG57_RS14715	COG0546	phosphoglycolate phosphatase activity
CDG57_RS14720	COG1716	ATPase activity
CDG57_RS14765	COG0181	hydroxymethylbilane synthase activity
CDG57_RS14775	COG3275	phosphorelay sensor kinase activity
CDG57_RS14815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDG57_RS14820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG57_RS14825	COG0772	Belongs to the SEDS family
CDG57_RS14850	COG4974	Belongs to the 'phage' integrase family
CDG57_RS14855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG57_RS14865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG57_RS14885	COG2197	response regulator
CDG57_RS14900	COG0793	Belongs to the peptidase S41A family
CDG57_RS14905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDG57_RS14910	COG0795	lipopolysaccharide-transporting ATPase activity
CDG57_RS14915	COG0795	lipopolysaccharide-transporting ATPase activity
CDG57_RS14950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG57_RS14950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG57_RS14960	COG0004	ammonium transporteR
CDG57_RS14965	COG0347	Belongs to the P(II) protein family
CDG57_RS14975	COG0606	chelatase, subunit chli
CDG57_RS15000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG57_RS15015	COG0318	PFAM AMP-dependent synthetase and ligase
CDG57_RS15035	COG2860	membrane
CDG57_RS15045	COG1253	flavin adenine dinucleotide binding
CDG57_RS15065	COG2814	Major facilitator Superfamily
CDG57_RS15080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG57_RS15085	COG0745	RESPONSE REGULATOR receiver
CDG57_RS15090	COG2205	protein histidine kinase activity
CDG57_RS15095	COG4452	Inner membrane protein CreD
CDG57_RS15120	COG2814	Major facilitator Superfamily
CDG57_RS15140	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDG57_RS15160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG57_RS15195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG57_RS15215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG57_RS15220	COG3162	membrane
CDG57_RS15225	COG2205	protein histidine kinase activity
CDG57_RS15225	COG0784	Response regulator, receiver
CDG57_RS15250	COG1652	LysM domain
CDG57_RS15255	COG0758	DNA mediated transformation
CDG57_RS15270	COG1309	transcriptional regulator
CDG57_RS15285	COG0386	Belongs to the glutathione peroxidase family
CDG57_RS15305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG57_RS15345	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDG57_RS15355	COG1121	(ABC) transporter
CDG57_RS15360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG57_RS15370	COG2837	iron assimilation
CDG57_RS15380	COG0281	malic enzyme
CDG57_RS15415	COG0519	Catalyzes the synthesis of GMP from XMP
CDG57_RS15415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG57_RS15420	COG4399	Belongs to the UPF0754 family
CDG57_RS15430	COG2259	Doxx family
CDG57_RS15435	COG0586	Pfam SNARE associated Golgi protein
CDG57_RS15450	COG1192	Involved in chromosome partitioning
CDG57_RS15460	COG0271	Belongs to the BolA IbaG family
CDG57_RS15495	COG3756	Protein conserved in bacteria
CDG57_RS15525	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDG57_RS15530	COG0842	Transport permease protein
CDG57_RS15535	COG1129	ABC transporter
CDG57_RS15535	COG0842	Transport permease protein
CDG57_RS15540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_RS15590	COG3550	peptidyl-serine autophosphorylation
CDG57_RS15595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG57_RS15675	COG0477	Major facilitator Superfamily
CDG57_RS15680	COG1024	Enoyl-CoA hydratase
CDG57_RS15685	COG1024	Enoyl-CoA hydratase
CDG57_RS15690	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS15695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG57_RS15715	COG1113	amino acid transport
CDG57_RS15720	COG0251	oxidation-reduction process
CDG57_RS15755	COG0564	pseudouridine synthase activity
CDG57_RS15800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDG57_RS15815	COG1802	Transcriptional regulator
CDG57_RS15820	COG1448	Aminotransferase
CDG57_RS15825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG57_RS15830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG57_RS15845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG57_RS15850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG57_RS15890	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDG57_RS15895	COG1088	dTDP-glucose 4,6-dehydratase activity
CDG57_RS15920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG57_RS15930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG57_RS15965	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDG57_RS15970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDG57_RS15980	COG0545	Peptidyl-prolyl cis-trans isomerase
CDG57_RS15985	COG0728	peptidoglycan biosynthetic process
CDG57_RS15990	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDG57_RS16005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG57_RS16040	COG0546	phosphoglycolate phosphatase activity
CDG57_RS16045	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_RS16055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG57_RS16055	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG57_RS16060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG57_RS16070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG57_RS16075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG57_RS16080	COG1116	anion transmembrane transporter activity
CDG57_RS16085	COG1309	transcriptional regulator
CDG57_RS16100	COG0196	riboflavin kinase activity
CDG57_RS16105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG57_RS16115	COG1047	Peptidyl-prolyl cis-trans
CDG57_RS16155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG57_RS16160	COG0657	acetylesterase activity
CDG57_RS16175	COG0583	DNA-binding transcription factor activity
CDG57_RS16185	COG0443	Heat shock 70 kDa protein
CDG57_RS16190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDG57_RS16215	COG2951	lytic endotransglycosylase activity
CDG57_RS16220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDG57_RS16240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG57_RS16260	COG1960	acyl-CoA dehydrogenase activity
CDG57_RS16265	COG0583	DNA-binding transcription factor activity
CDG57_RS16275	COG0861	Integral membrane protein TerC family
CDG57_RS16285	COG0754	glutathionylspermidine amidase activity
CDG57_RS16295	COG0402	S-adenosylhomocysteine deaminase activity
CDG57_RS16325	COG0706	membrane insertase activity