locus-tag	class	description
OTEC02_RS00010	COG0592	DNA-directed DNA polymerase activity
OTEC02_RS00020	COG0187	DNA topoisomerase II activity
OTEC02_RS00035	COG0488	(ABC) transporter
OTEC02_RS00065	COG0596	Alpha beta hydrolase
OTEC02_RS00070	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OTEC02_RS00075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OTEC02_RS00105	COG0625	glutathione transferase activity
OTEC02_RS00115	COG0733	neurotransmitter:sodium symporter activity
OTEC02_RS00155	COG2233	PERMEase
OTEC02_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_RS00205	COG2814	Major facilitator Superfamily
OTEC02_RS00210	COG0656	L-ascorbic acid biosynthetic process
OTEC02_RS00215	COG0583	DNA-binding transcription factor activity
OTEC02_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_RS00235	COG1064	alcohol dehydrogenase
OTEC02_RS00240	COG2818	Glycosylase
OTEC02_RS00255	COG1194	a g-specific adenine glycosylase
OTEC02_RS00270	COG5487	UPF0391 membrane protein
OTEC02_RS00275	COG2983	Belongs to the UPF0260 family
OTEC02_RS00280	COG2133	pyrroloquinoline quinone binding
OTEC02_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OTEC02_RS00290	COG2116	formate transmembrane transporter activity
OTEC02_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OTEC02_RS00315	COG1335	isochorismatase
OTEC02_RS00320	COG0385	Bile acid
OTEC02_RS00325	COG0534	Mate efflux family protein
OTEC02_RS00330	COG1683	Conserved Protein
OTEC02_RS00345	COG0346	lactoylglutathione lyase activity
OTEC02_RS00350	COG0625	glutathione transferase activity
OTEC02_RS00360	COG1113	amino acid transport
OTEC02_RS00370	COG0523	cobalamin synthesis protein
OTEC02_RS00380	COG2188	Transcriptional regulator
OTEC02_RS00410	COG0010	Belongs to the arginase family
OTEC02_RS00420	COG0546	phosphoglycolate phosphatase activity
OTEC02_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OTEC02_RS00445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OTEC02_RS00455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OTEC02_RS00460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OTEC02_RS00565	COG0534	Mate efflux family protein
OTEC02_RS00570	COG0436	Aminotransferase
OTEC02_RS00575	COG2733	membrane
OTEC02_RS00590	COG2918	glutathione biosynthetic process
OTEC02_RS00605	COG1388	LysM domain
OTEC02_RS00605	COG0791	NLP P60 protein
OTEC02_RS00620	COG3150	esterase
OTEC02_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OTEC02_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_RS00650	COG2233	PERMEase
OTEC02_RS00655	COG2351	hydroxyisourate hydrolase activity
OTEC02_RS00690	COG3706	GGDEF domain
OTEC02_RS00705	COG1393	Belongs to the ArsC family
OTEC02_RS00710	COG0708	Exodeoxyribonuclease III
OTEC02_RS00735	COG0189	ligase activity
OTEC02_RS00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OTEC02_RS00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OTEC02_RS00780	COG4942	peptidase
OTEC02_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_RS00800	COG2119	membrane
OTEC02_RS00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_RS00810	COG0426	domain, Protein
OTEC02_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OTEC02_RS00855	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS00860	COG1519	Transferase
OTEC02_RS00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OTEC02_RS00870	COG0668	transmembrane transport
OTEC02_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OTEC02_RS00885	COG1335	isochorismatase
OTEC02_RS00890	COG1522	sequence-specific DNA binding
OTEC02_RS00915	COG2198	Histidine kinase
OTEC02_RS00915	COG0784	Response regulator, receiver
OTEC02_RS00915	COG2205	protein histidine kinase activity
OTEC02_RS00920	COG3162	membrane
OTEC02_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OTEC02_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OTEC02_RS00945	COG3706	GGDEF domain
OTEC02_RS00960	COG1309	transcriptional regulator
OTEC02_RS00980	COG0300	oxidoreductase activity
OTEC02_RS00990	COG0352	thiamine-phosphate diphosphorylase activity
OTEC02_RS00990	COG0351	phosphomethylpyrimidine kinase
OTEC02_RS00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OTEC02_RS01000	COG2814	Major facilitator Superfamily
OTEC02_RS01015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OTEC02_RS01025	COG1113	amino acid transport
OTEC02_RS01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OTEC02_RS01040	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS01050	COG1335	isochorismatase
OTEC02_RS01090	COG0583	DNA-binding transcription factor activity
OTEC02_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS01110	COG2814	Major facilitator Superfamily
OTEC02_RS01115	COG0583	DNA-binding transcription factor activity
OTEC02_RS01135	COG0667	Aldo Keto reductase
OTEC02_RS01170	COG1733	regulation of RNA biosynthetic process
OTEC02_RS01175	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_RS01240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OTEC02_RS01260	COG0697	spore germination
OTEC02_RS01285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OTEC02_RS01315	COG0427	acetyl-CoA hydrolase
OTEC02_RS01340	COG0659	secondary active sulfate transmembrane transporter activity
OTEC02_RS01345	COG4221	oxidoreductase activity
OTEC02_RS01350	COG2873	o-acetylhomoserine
OTEC02_RS01355	COG0488	(ABC) transporter
OTEC02_RS01435	COG0833	amino acid
OTEC02_RS01480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OTEC02_RS01485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OTEC02_RS01500	COG2226	methyltransferase
OTEC02_RS01555	COG0067	glutamate synthase
OTEC02_RS01555	COG0069	glutamate synthase activity
OTEC02_RS01555	COG0070	glutamate synthase
OTEC02_RS01560	COG0493	'glutamate synthase
OTEC02_RS01570	COG1704	LemA family
OTEC02_RS01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OTEC02_RS01585	COG4969	Belongs to the N-Me-Phe pilin family
OTEC02_RS01595	COG3307	-O-antigen
OTEC02_RS01615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OTEC02_RS01625	COG0194	GDP metabolic process
OTEC02_RS01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OTEC02_RS01685	COG0335	large ribosomal subunit rRNA binding
OTEC02_RS01695	COG5380	lipid catabolic process
OTEC02_RS01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OTEC02_RS01720	COG5006	permease, DMT superfamily
OTEC02_RS01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OTEC02_RS01730	COG0277	FAD linked oxidase domain protein
OTEC02_RS01740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OTEC02_RS01745	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_RS01760	COG1289	transmembrane transporter activity
OTEC02_RS01770	COG0628	permease
OTEC02_RS01775	COG1192	Involved in chromosome partitioning
OTEC02_RS01805	COG0833	amino acid
OTEC02_RS01810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OTEC02_RS01815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OTEC02_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS01850	COG1404	Belongs to the peptidase S8 family
OTEC02_RS01865	COG0583	DNA-binding transcription factor activity
OTEC02_RS01870	COG1794	racemase activity, acting on amino acids and derivatives
OTEC02_RS01875	COG0583	DNA-binding transcription factor activity
OTEC02_RS01890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OTEC02_RS01905	COG0752	glycyl-tRNA synthetase alpha subunit
OTEC02_RS01930	COG0517	IMP dehydrogenase activity
OTEC02_RS01935	COG1983	PspC domain protein
OTEC02_RS01945	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS01960	COG0408	coproporphyrinogen oxidase activity
OTEC02_RS01980	COG0513	Belongs to the DEAD box helicase family
OTEC02_RS01990	COG1127	ABC transporter
OTEC02_RS01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OTEC02_RS02005	COG2854	intermembrane phospholipid transfer
OTEC02_RS02015	COG0598	Magnesium transport protein CorA
OTEC02_RS02025	COG0494	nUDIX hydrolase
OTEC02_RS02030	COG1040	competence protein
OTEC02_RS02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OTEC02_RS02055	COG1946	Acyl-CoA thioesterase
OTEC02_RS02060	COG1301	dicarboxylic acid transport
OTEC02_RS02075	COG1959	2 iron, 2 sulfur cluster binding
OTEC02_RS02080	COG1017	nitric oxide dioxygenase activity
OTEC02_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_RS02085	COG0433	COG0433 Predicted ATPase
OTEC02_RS02090	COG0626	cystathionine gamma-synthase activity
OTEC02_RS02105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OTEC02_RS02110	COG0088	Forms part of the polypeptide exit tunnel
OTEC02_RS02245	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS02250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OTEC02_RS02280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OTEC02_RS02285	COG0339	signal peptide processing
OTEC02_RS02290	COG0557	exoribonuclease II activity
OTEC02_RS02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
OTEC02_RS02340	COG1295	ribonuclease BN
OTEC02_RS02375	COG1702	phosphate starvation-inducible protein PhoH
OTEC02_RS02385	COG1196	nuclear chromosome segregation
OTEC02_RS02385	COG0739	heme binding
OTEC02_RS02385	COG0741	lytic transglycosylase activity
OTEC02_RS02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OTEC02_RS02420	COG1183	phosphatidylcholine synthase activity
OTEC02_RS02465	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS02470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OTEC02_RS02475	COG1309	transcriptional regulator
OTEC02_RS02490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OTEC02_RS02495	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS02515	COG2969	positive regulation of protein catabolic process
OTEC02_RS02525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OTEC02_RS02530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OTEC02_RS02535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OTEC02_RS02540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OTEC02_RS02545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OTEC02_RS02565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OTEC02_RS02575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OTEC02_RS02580	COG1408	metallophosphoesterase
OTEC02_RS02585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OTEC02_RS02585	COG2885	chlorophyll binding
OTEC02_RS02590	COG2199	diguanylate cyclase activity
OTEC02_RS02635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_RS02660	COG1607	acyl-coa hydrolase
OTEC02_RS02695	COG2350	Protein conserved in bacteria
OTEC02_RS02710	COG3781	membrane
OTEC02_RS02720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OTEC02_RS02735	COG1862	Preprotein translocase
OTEC02_RS02755	COG0582	viral genome integration into host DNA
OTEC02_RS02860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OTEC02_RS02900	COG0726	polysaccharide deacetylase
OTEC02_RS02905	COG0463	Glycosyl transferase, family 2
OTEC02_RS02910	COG0438	transferase activity, transferring glycosyl groups
OTEC02_RS02925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OTEC02_RS02925	COG1215	transferase activity, transferring glycosyl groups
OTEC02_RS02980	COG0625	glutathione transferase activity
OTEC02_RS02985	COG0583	DNA-binding transcription factor activity
OTEC02_RS02990	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS02995	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS03005	COG2205	protein histidine kinase activity
OTEC02_RS03010	COG0745	RESPONSE REGULATOR receiver
OTEC02_RS03020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OTEC02_RS03040	COG2096	Adenosyltransferase
OTEC02_RS03045	COG4206	TonB-dependent receptor
OTEC02_RS03090	COG0285	dihydrofolate synthase activity
OTEC02_RS03115	COG0450	alkyl hydroperoxide reductase
OTEC02_RS03130	COG0477	Major facilitator Superfamily
OTEC02_RS03135	COG1272	protein, Hemolysin III
OTEC02_RS03145	COG2153	protein acetylation
OTEC02_RS03165	COG0183	Belongs to the thiolase family
OTEC02_RS03170	COG2207	Transcriptional regulator
OTEC02_RS03190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_RS03210	COG0183	Belongs to the thiolase family
OTEC02_RS03220	COG2885	chlorophyll binding
OTEC02_RS03220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OTEC02_RS03225	COG1690	Belongs to the RtcB family
OTEC02_RS03230	COG0833	amino acid
OTEC02_RS03240	COG2233	PERMEase
OTEC02_RS03245	COG1217	gtp-binding protein TYPA
OTEC02_RS03270	COG2094	Belongs to the DNA glycosylase MPG family
OTEC02_RS03275	COG4772	TonB-dependent receptor
OTEC02_RS03280	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS03285	COG0679	Auxin Efflux Carrier
OTEC02_RS03295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OTEC02_RS03300	COG0354	folic acid binding
OTEC02_RS03315	COG3189	MarR family transcriptional regulator
OTEC02_RS03320	COG2824	Alkylphosphonate utilization operon protein PhnA
OTEC02_RS03325	COG3422	double-strand break repair
OTEC02_RS03365	COG0840	transmembrane signaling receptor activity
OTEC02_RS03380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OTEC02_RS03395	COG5510	response to toxic substance
OTEC02_RS03405	COG2832	Protein of unknown function (DUF454)
OTEC02_RS03410	COG1376	ErfK ybiS ycfS ynhG family protein
OTEC02_RS03450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OTEC02_RS03460	COG1289	transmembrane transporter activity
OTEC02_RS03465	COG2814	Major facilitator Superfamily
OTEC02_RS03490	COG1115	amino acid carrier protein
OTEC02_RS03495	COG1752	Esterase of the alpha-beta hydrolase superfamily
OTEC02_RS03500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OTEC02_RS03505	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OTEC02_RS03530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OTEC02_RS03540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OTEC02_RS03545	COG1077	Cell shape determining protein MreB Mrl
OTEC02_RS03550	COG1792	Involved in formation and maintenance of cell shape
OTEC02_RS03555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OTEC02_RS03560	COG0424	maF-like protein
OTEC02_RS03565	COG1530	ribonuclease E activity
OTEC02_RS03575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_RS03595	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_RS03620	COG2207	Transcriptional regulator
OTEC02_RS03645	COG1113	amino acid transport
OTEC02_RS03650	COG2828	Protein conserved in bacteria
OTEC02_RS03655	COG0142	geranyltranstransferase activity
OTEC02_RS03660	COG2315	Protein conserved in bacteria
OTEC02_RS03675	COG1752	Esterase of the alpha-beta hydrolase superfamily
OTEC02_RS03700	COG2194	sulfuric ester hydrolase activity
OTEC02_RS03705	COG0745	RESPONSE REGULATOR receiver
OTEC02_RS03710	COG0642	Histidine kinase
OTEC02_RS03720	COG0004	ammonium transporteR
OTEC02_RS03725	COG0583	DNA-binding transcription factor activity
OTEC02_RS03745	COG0525	valine-tRNA ligase activity
OTEC02_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS03765	COG0393	Putative heavy-metal-binding
OTEC02_RS03770	COG0393	Putative heavy-metal-binding
OTEC02_RS03775	COG1538	Outer membrane efflux protein
OTEC02_RS03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_RS03790	COG0671	phosphoesterase, PA-phosphatase related
OTEC02_RS03815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OTEC02_RS03830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OTEC02_RS03830	COG1648	precorrin-2 dehydrogenase activity
OTEC02_RS03835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OTEC02_RS03870	COG0531	amino acid
OTEC02_RS03885	COG0321	lipoyl(octanoyl) transferase activity
OTEC02_RS03895	COG2921	Belongs to the UPF0250 family
OTEC02_RS03935	COG2009	succinate dehydrogenase
OTEC02_RS03940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OTEC02_RS03945	COG1053	succinate dehydrogenase
OTEC02_RS03950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OTEC02_RS03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_RS04000	COG2268	Band 7 protein
OTEC02_RS04010	COG2354	Protein conserved in bacteria
OTEC02_RS04015	COG2321	neutral zinc metallopeptidase
OTEC02_RS04035	COG2843	Capsule synthesis protein
OTEC02_RS04050	COG0589	response to stress
OTEC02_RS04070	COG0505	Belongs to the CarA family
OTEC02_RS04105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OTEC02_RS04110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OTEC02_RS04160	COG0477	Major facilitator Superfamily
OTEC02_RS04165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OTEC02_RS04180	COG1597	lipid kinase activity
OTEC02_RS04185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OTEC02_RS04215	COG0584	glycerophosphoryl diester phosphodiesterase
OTEC02_RS04235	COG0741	lytic transglycosylase activity
OTEC02_RS04255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OTEC02_RS04260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OTEC02_RS04295	COG1309	transcriptional regulator
OTEC02_RS04300	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS04305	COG0596	Alpha beta hydrolase
OTEC02_RS04305	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_RS04310	COG0596	Alpha beta hydrolase
OTEC02_RS04310	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_RS04315	COG0596	Alpha beta hydrolase
OTEC02_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS04325	COG0583	DNA-binding transcription factor activity
OTEC02_RS04330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OTEC02_RS04335	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS04350	COG0778	Nitroreductase
OTEC02_RS04355	COG1929	Belongs to the glycerate kinase type-1 family
OTEC02_RS04360	COG0243	molybdopterin cofactor binding
OTEC02_RS04365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OTEC02_RS04370	COG3339	Conserved Protein
OTEC02_RS04395	COG1115	amino acid carrier protein
OTEC02_RS04400	COG1113	amino acid transport
OTEC02_RS04410	COG0019	diaminopimelate decarboxylase activity
OTEC02_RS04420	COG1280	lysine exporter protein (LysE YggA)
OTEC02_RS04425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OTEC02_RS04455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_RS04485	COG4591	ABC-type transport system involved in lipoprotein release permease component
OTEC02_RS04490	COG1136	(ABC) transporter
OTEC02_RS04495	COG2333	competence protein COMEC
OTEC02_RS04495	COG0658	competence protein
OTEC02_RS04505	COG0616	signal peptide processing
OTEC02_RS04505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OTEC02_RS04510	COG0596	Alpha beta hydrolase
OTEC02_RS04515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OTEC02_RS04525	COG0628	permease
OTEC02_RS04565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OTEC02_RS04585	COG0823	Involved in the tonB-independent uptake of proteins
OTEC02_RS04605	COG0824	Thioesterase
OTEC02_RS04610	COG1473	amidohydrolase
OTEC02_RS04630	COG0047	phosphoribosylformylglycinamidine synthase activity
OTEC02_RS04630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OTEC02_RS04635	COG2814	Major facilitator Superfamily
OTEC02_RS04640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OTEC02_RS04645	COG1024	Enoyl-CoA hydratase
OTEC02_RS04650	COG1056	cytidyltransferase-related domain
OTEC02_RS04650	COG1051	belongs to the nudix hydrolase family
OTEC02_RS04665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OTEC02_RS04680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OTEC02_RS04685	COG0602	queuosine metabolic process
OTEC02_RS04695	COG4625	pathogenesis
OTEC02_RS04700	COG0583	DNA-binding transcription factor activity
OTEC02_RS04705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OTEC02_RS04710	COG4208	sulfate ABC transporter
OTEC02_RS04715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OTEC02_RS04725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OTEC02_RS04730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OTEC02_RS04735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OTEC02_RS04755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OTEC02_RS04765	COG0481	GTPase activity
OTEC02_RS04770	COG0681	Belongs to the peptidase S26 family
OTEC02_RS04780	COG0571	ribonuclease III activity
OTEC02_RS04785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OTEC02_RS04795	COG1381	Involved in DNA repair and RecF pathway recombination
OTEC02_RS04800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OTEC02_RS04810	COG4221	oxidoreductase activity
OTEC02_RS04840	COG0436	Aminotransferase
OTEC02_RS04860	COG0556	nucleotide-excision repair
OTEC02_RS04870	COG2962	Rard protein
OTEC02_RS04915	COG2070	2-Nitropropane dioxygenase
OTEC02_RS04930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OTEC02_RS04945	COG1215	transferase activity, transferring glycosyl groups
OTEC02_RS04960	COG0415	Belongs to the DNA photolyase family
OTEC02_RS04970	COG1252	NADH dehydrogenase
OTEC02_RS04975	COG1686	Belongs to the peptidase S11 family
OTEC02_RS04990	COG1187	pseudouridine synthase activity
OTEC02_RS05005	COG0477	Major facilitator Superfamily
OTEC02_RS05010	COG0583	DNA-binding transcription factor activity
OTEC02_RS05015	COG1823	symporter activity
OTEC02_RS05025	COG0612	Peptidase, M16
OTEC02_RS05050	COG0352	thiamine-phosphate diphosphorylase activity
OTEC02_RS05085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_RS05110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OTEC02_RS05115	COG0076	glutamate decarboxylase activity
OTEC02_RS05125	COG1522	sequence-specific DNA binding
OTEC02_RS05130	COG3961	Belongs to the TPP enzyme family
OTEC02_RS05135	COG1113	amino acid transport
OTEC02_RS05140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OTEC02_RS05145	COG0573	inorganic phosphate transmembrane transporter activity
OTEC02_RS05155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OTEC02_RS05160	COG0616	signal peptide processing
OTEC02_RS05195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OTEC02_RS05200	COG1686	Belongs to the peptidase S11 family
OTEC02_RS05220	COG4942	peptidase
OTEC02_RS05220	COG1388	LysM domain
OTEC02_RS05225	COG0583	DNA-binding transcription factor activity
OTEC02_RS05230	COG1067	ATP-dependent peptidase activity
OTEC02_RS05270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OTEC02_RS05275	COG1966	Carbon starvation protein
OTEC02_RS05280	COG2879	small protein
OTEC02_RS05295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OTEC02_RS05315	COG1741	Belongs to the pirin family
OTEC02_RS05330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_RS05340	COG4605	iron ion homeostasis
OTEC02_RS05345	COG4604	ABC transporter, ATP-binding protein
OTEC02_RS05350	COG4607	ABC-type enterochelin transport system periplasmic component
OTEC02_RS05355	COG4774	siderophore transport
OTEC02_RS05365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_RS05370	COG1021	2,3-dihydroxybenzoate-AMP ligase
OTEC02_RS05375	COG1535	isochorismatase
OTEC02_RS05375	COG3433	isochorismatase activity
OTEC02_RS05390	COG1132	(ABC) transporter
OTEC02_RS05395	COG1132	(ABC) transporter
OTEC02_RS05400	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OTEC02_RS05410	COG1169	isochorismate synthase
OTEC02_RS05430	COG3739	integral membrane protein
OTEC02_RS05450	COG0302	gtp cyclohydrolase
OTEC02_RS05460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OTEC02_RS05470	COG2840	Smr protein MutS2
OTEC02_RS05485	COG0512	Glutamine amidotransferase of anthranilate synthase
OTEC02_RS05505	COG0174	glutamine synthetase
OTEC02_RS05515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OTEC02_RS05550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OTEC02_RS05555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OTEC02_RS05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OTEC02_RS05580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OTEC02_RS05585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OTEC02_RS05590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OTEC02_RS05605	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS05610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OTEC02_RS05615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_RS05625	COG2223	nitrite transmembrane transporter activity
OTEC02_RS05635	COG0024	Methionine aminopeptidase
OTEC02_RS05640	COG0052	Belongs to the universal ribosomal protein uS2 family
OTEC02_RS05655	COG2207	Transcriptional regulator
OTEC02_RS05680	COG2951	lytic endotransglycosylase activity
OTEC02_RS05685	COG0772	Belongs to the SEDS family
OTEC02_RS05700	COG0842	Transport permease protein
OTEC02_RS05705	COG1131	(ABC) transporter
OTEC02_RS05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_RS05760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OTEC02_RS05765	COG4215	(ABC) transporter
OTEC02_RS05770	COG4160	amino acid transport
OTEC02_RS05775	COG4598	ABC transporter
OTEC02_RS05785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OTEC02_RS05790	COG0826	peptidase U32
OTEC02_RS05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_RS05810	COG1720	tRNA m6t6A37 methyltransferase activity
OTEC02_RS05820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OTEC02_RS05835	COG0642	Histidine kinase
OTEC02_RS05845	COG0494	nUDIX hydrolase
OTEC02_RS05855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OTEC02_RS05860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OTEC02_RS05865	COG3139	Protein of unknown function (DUF1315)
OTEC02_RS05870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OTEC02_RS05880	COG1301	dicarboxylic acid transport
OTEC02_RS05885	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS05905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OTEC02_RS05915	COG2195	Cleaves the N-terminal amino acid of tripeptides
OTEC02_RS05920	COG1234	tRNA 3'-trailer cleavage
OTEC02_RS05945	COG2363	Small membrane protein
OTEC02_RS05965	COG0513	Belongs to the DEAD box helicase family
OTEC02_RS05975	COG0778	Nitroreductase
OTEC02_RS06005	COG1286	toxin biosynthetic process
OTEC02_RS06030	COG4783	chaperone-mediated protein folding
OTEC02_RS06035	COG1610	YqeY-like protein
OTEC02_RS06090	COG1278	Cold shock
OTEC02_RS06110	COG2207	Transcriptional regulator
OTEC02_RS06115	COG3243	poly(R)-hydroxyalkanoic acid synthase
OTEC02_RS06120	COG1335	isochorismatase
OTEC02_RS06125	COG0583	DNA-binding transcription factor activity
OTEC02_RS06130	COG0786	glutamate:sodium symporter activity
OTEC02_RS06135	COG0475	glutathione-regulated potassium exporter activity
OTEC02_RS06135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OTEC02_RS06150	COG1309	transcriptional regulator
OTEC02_RS06160	COG2985	domain, Protein
OTEC02_RS06170	COG2995	paraquat-inducible protein a
OTEC02_RS06175	COG3008	intermembrane lipid transfer
OTEC02_RS06175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OTEC02_RS06185	COG2351	hydroxyisourate hydrolase activity
OTEC02_RS06225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OTEC02_RS06235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OTEC02_RS06240	COG0642	Histidine kinase
OTEC02_RS06245	COG0745	RESPONSE REGULATOR receiver
OTEC02_RS06265	COG1794	racemase activity, acting on amino acids and derivatives
OTEC02_RS06275	COG2175	clavaminate synthase activity
OTEC02_RS06280	COG3246	L-lysine catabolic process to acetate
OTEC02_RS06285	COG2814	Major facilitator Superfamily
OTEC02_RS06300	COG2855	membrane
OTEC02_RS06335	COG2814	Major facilitator Superfamily
OTEC02_RS06360	COG1301	dicarboxylic acid transport
OTEC02_RS06370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OTEC02_RS06375	COG2011	ABC-type metal ion transport system permease component
OTEC02_RS06380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OTEC02_RS06390	COG0151	Belongs to the GarS family
OTEC02_RS06400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OTEC02_RS06430	COG0735	belongs to the Fur family
OTEC02_RS06455	COG2308	Evidence 4 Homologs of previously reported genes of
OTEC02_RS06465	COG1305	Transglutaminase-like
OTEC02_RS06475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OTEC02_RS06480	COG0305	Participates in initiation and elongation during chromosome replication
OTEC02_RS06505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OTEC02_RS06515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OTEC02_RS06545	COG1649	PFAM Uncharacterised BCR, COG1649
OTEC02_RS06545	COG0726	polysaccharide deacetylase
OTEC02_RS06550	COG1215	transferase activity, transferring glycosyl groups
OTEC02_RS06555	COG3658	cytochrome
OTEC02_RS06565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OTEC02_RS06580	COG0583	DNA-binding transcription factor activity
OTEC02_RS06595	COG2890	protein-(glutamine-N5) methyltransferase activity
OTEC02_RS06600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_RS06605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_RS06620	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS06625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_RS06640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OTEC02_RS06650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OTEC02_RS06655	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OTEC02_RS06665	COG2205	protein histidine kinase activity
OTEC02_RS06675	COG0174	glutamine synthetase
OTEC02_RS06695	COG0729	surface antigen
OTEC02_RS06745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OTEC02_RS06750	COG2814	Major facilitator Superfamily
OTEC02_RS06760	COG0583	DNA-binding transcription factor activity
OTEC02_RS06775	COG1187	pseudouridine synthase activity
OTEC02_RS06795	COG0802	atpase or kinase
OTEC02_RS06810	COG1923	regulation of RNA biosynthetic process
OTEC02_RS06815	COG0697	spore germination
OTEC02_RS06825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OTEC02_RS06840	COG0519	Catalyzes the synthesis of GMP from XMP
OTEC02_RS06840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OTEC02_RS06845	COG4302	ethanolamine ammonia-lyase activity
OTEC02_RS06850	COG4303	Ethanolamine ammonia lyase large subunit
OTEC02_RS06855	COG0531	amino acid
OTEC02_RS06880	COG1454	alcohol dehydrogenase
OTEC02_RS06885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OTEC02_RS06895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OTEC02_RS06915	COG0308	aminopeptidase N
OTEC02_RS06955	COG1605	Chorismate mutase
OTEC02_RS06980	COG4772	TonB-dependent receptor
OTEC02_RS06985	COG4774	siderophore transport
OTEC02_RS07030	COG3772	lysozyme
OTEC02_RS07040	COG1733	regulation of RNA biosynthetic process
OTEC02_RS07065	COG0583	DNA-binding transcription factor activity
OTEC02_RS07105	COG0488	(ABC) transporter
OTEC02_RS07110	COG0589	response to stress
OTEC02_RS07130	COG3135	benzoate transporter
OTEC02_RS07135	COG1522	sequence-specific DNA binding
OTEC02_RS07145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OTEC02_RS07150	COG0583	DNA-binding transcription factor activity
OTEC02_RS07160	COG0183	Belongs to the thiolase family
OTEC02_RS07170	COG2030	dehydratase
OTEC02_RS07175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OTEC02_RS07200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OTEC02_RS07210	COG0824	Thioesterase
OTEC02_RS07215	COG1454	alcohol dehydrogenase
OTEC02_RS07240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OTEC02_RS07270	COG0069	glutamate synthase activity
OTEC02_RS07295	COG2814	Major facilitator Superfamily
OTEC02_RS07305	COG0439	Biotin carboxylase
OTEC02_RS07310	COG0511	ligase activity, forming carbon-carbon bonds
OTEC02_RS07340	COG2814	Major facilitator Superfamily
OTEC02_RS07345	COG4264	IucA IucC family
OTEC02_RS07350	COG4264	IucA IucC family
OTEC02_RS07360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OTEC02_RS07380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_RS07380	COG1116	anion transmembrane transporter activity
OTEC02_RS07395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_RS07395	COG2146	nitrite reductase [NAD(P)H] activity
OTEC02_RS07400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_RS07405	COG0243	molybdopterin cofactor binding
OTEC02_RS07415	COG0243	molybdopterin cofactor binding
OTEC02_RS07420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OTEC02_RS07435	COG0315	cyclic pyranopterin monophosphate synthase activity
OTEC02_RS07435	COG0521	Mo-molybdopterin cofactor biosynthetic process
OTEC02_RS07440	COG0303	'Molybdopterin
OTEC02_RS07450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_RS07455	COG0697	spore germination
OTEC02_RS07480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OTEC02_RS07545	COG2204	response regulator
OTEC02_RS07550	COG3852	Histidine kinase
OTEC02_RS07575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OTEC02_RS07595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OTEC02_RS07615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OTEC02_RS07630	COG2137	regulation of response to DNA damage stimulus
OTEC02_RS07640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OTEC02_RS07645	COG1011	Hydrolase
OTEC02_RS07660	COG1522	sequence-specific DNA binding
OTEC02_RS07670	COG1113	amino acid transport
OTEC02_RS07690	COG0659	secondary active sulfate transmembrane transporter activity
OTEC02_RS07710	COG3300	MHYT domain
OTEC02_RS07710	COG5001	Diguanylate cyclase
OTEC02_RS07725	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OTEC02_RS07725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OTEC02_RS07725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OTEC02_RS07730	COG1105	Belongs to the carbohydrate kinase PfkB family
OTEC02_RS07735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OTEC02_RS07735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OTEC02_RS07755	COG3193	protein, possibly involved in utilization of glycolate and propanediol
OTEC02_RS07765	COG0024	Methionine aminopeptidase
OTEC02_RS07770	COG0583	DNA-binding transcription factor activity
OTEC02_RS07780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OTEC02_RS07785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OTEC02_RS07790	COG0517	IMP dehydrogenase activity
OTEC02_RS07790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OTEC02_RS07815	COG0552	protein localization to endoplasmic reticulum
OTEC02_RS07825	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OTEC02_RS07840	COG4890	Cyd operon protein YbgT
OTEC02_RS07845	COG1294	oxidase, subunit
OTEC02_RS07860	COG1585	Membrane protein implicated in regulation of membrane protease activity
OTEC02_RS07870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OTEC02_RS07885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OTEC02_RS07890	COG0569	domain protein
OTEC02_RS07895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OTEC02_RS07925	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OTEC02_RS07930	COG0542	response to heat
OTEC02_RS07955	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_RS07955	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS07995	COG0148	phosphopyruvate hydratase activity
OTEC02_RS08000	COG2323	membrane
OTEC02_RS08010	COG4773	Receptor
OTEC02_RS08015	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OTEC02_RS08025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_RS08030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_RS08035	COG0183	Belongs to the thiolase family
OTEC02_RS08040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OTEC02_RS08045	COG0596	Alpha beta hydrolase
OTEC02_RS08050	COG2271	Major facilitator Superfamily
OTEC02_RS08055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OTEC02_RS08060	COG3485	protocatechuate 3,4-dioxygenase
OTEC02_RS08065	COG3485	protocatechuate 3,4-dioxygenase
OTEC02_RS08070	COG0710	3-dehydroquinate dehydratase activity
OTEC02_RS08075	COG3420	alginic acid biosynthetic process
OTEC02_RS08080	COG3659	wide pore channel activity
OTEC02_RS08085	COG4993	Dehydrogenase
OTEC02_RS08095	COG2391	methyltransferase activity
OTEC02_RS08110	COG1414	Transcriptional regulator
OTEC02_RS08115	COG0583	DNA-binding transcription factor activity
OTEC02_RS08120	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS08145	COG2814	Major facilitator Superfamily
OTEC02_RS08155	COG0154	amidase activity
OTEC02_RS08175	COG4638	Rieske (2fe-2S)
OTEC02_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_RS08205	COG3733	amine oxidase
OTEC02_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS08230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OTEC02_RS08235	COG0183	Belongs to the thiolase family
OTEC02_RS08240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_RS08245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_RS08255	COG4829	muconolactone delta-isomerase
OTEC02_RS08260	COG4948	Mandelate Racemase Muconate Lactonizing
OTEC02_RS08265	COG0583	DNA-binding transcription factor activity
OTEC02_RS08275	COG2186	Transcriptional regulator
OTEC02_RS08295	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS08300	COG1309	transcriptional regulator
OTEC02_RS08305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OTEC02_RS08335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OTEC02_RS08340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_RS08345	COG0745	RESPONSE REGULATOR receiver
OTEC02_RS08350	COG2205	protein histidine kinase activity
OTEC02_RS08380	COG2072	flavoprotein involved in K transport
OTEC02_RS08385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OTEC02_RS08420	COG1946	Acyl-CoA thioesterase
OTEC02_RS08425	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS08430	COG0583	DNA-binding transcription factor activity
OTEC02_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08470	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS08475	COG0183	Belongs to the thiolase family
OTEC02_RS08485	COG2271	Major facilitator Superfamily
OTEC02_RS08490	COG0251	oxidation-reduction process
OTEC02_RS08500	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS08520	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS08525	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08530	COG3829	transcription factor binding
OTEC02_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08555	COG1414	Transcriptional regulator
OTEC02_RS08560	COG1053	succinate dehydrogenase
OTEC02_RS08575	COG3659	wide pore channel activity
OTEC02_RS08580	COG1309	transcriptional regulator
OTEC02_RS08600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OTEC02_RS08610	COG1053	succinate dehydrogenase
OTEC02_RS08615	COG1053	succinate dehydrogenase
OTEC02_RS08625	COG1846	Transcriptional regulator
OTEC02_RS08630	COG1024	Enoyl-CoA hydratase
OTEC02_RS08635	COG2814	Major facilitator Superfamily
OTEC02_RS08655	COG0644	oxidoreductase
OTEC02_RS08655	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OTEC02_RS08665	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS08670	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS08680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OTEC02_RS08690	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS08705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OTEC02_RS08715	COG0583	DNA-binding transcription factor activity
OTEC02_RS08735	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS08740	COG1454	alcohol dehydrogenase
OTEC02_RS08745	COG3485	protocatechuate 3,4-dioxygenase
OTEC02_RS08760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_RS08765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_RS08770	COG0183	Belongs to the thiolase family
OTEC02_RS08795	COG1234	tRNA 3'-trailer cleavage
OTEC02_RS08800	COG2271	Major facilitator Superfamily
OTEC02_RS08810	COG3971	2-oxopent-4-enoate hydratase activity
OTEC02_RS08815	COG4569	acetaldehyde dehydrogenase (acetylating) activity
OTEC02_RS08835	COG0583	DNA-binding transcription factor activity
OTEC02_RS08840	COG4638	Rieske (2fe-2S)
OTEC02_RS08845	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OTEC02_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08860	COG3384	dioxygenase
OTEC02_RS08865	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_RS08870	COG2814	Major facilitator Superfamily
OTEC02_RS08875	COG2814	Major facilitator Superfamily
OTEC02_RS08880	COG0583	DNA-binding transcription factor activity
OTEC02_RS08900	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_RS08900	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS08945	COG1309	transcriptional regulator
OTEC02_RS08950	COG0604	alcohol dehydrogenase
OTEC02_RS08950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_RS08950	COG4221	oxidoreductase activity
OTEC02_RS08950	COG3321	synthase
OTEC02_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS08970	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS08980	COG0583	DNA-binding transcription factor activity
OTEC02_RS09095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_RS09110	COG2271	Major facilitator Superfamily
OTEC02_RS09115	COG1566	PFAM secretion protein HlyD family protein
OTEC02_RS09130	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS09135	COG0129	dihydroxy-acid dehydratase activity
OTEC02_RS09140	COG0129	dihydroxy-acid dehydratase activity
OTEC02_RS09150	COG0583	DNA-binding transcription factor activity
OTEC02_RS09155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OTEC02_RS09165	COG2084	Dehydrogenase
OTEC02_RS09170	COG2207	Transcriptional regulator
OTEC02_RS09175	COG1064	alcohol dehydrogenase
OTEC02_RS09185	COG1309	transcriptional regulator
OTEC02_RS09200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OTEC02_RS09205	COG1120	ATPase activity
OTEC02_RS09215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OTEC02_RS09280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OTEC02_RS09315	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
OTEC02_RS09330	COG1073	alpha beta
OTEC02_RS09345	COG3539	Fimbrial protein
OTEC02_RS09370	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OTEC02_RS09380	COG0753	catalase activity
OTEC02_RS09400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OTEC02_RS09465	COG1535	isochorismatase
OTEC02_RS09465	COG3433	isochorismatase activity
OTEC02_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS09490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OTEC02_RS09495	COG4149	molybdate abc transporter
OTEC02_RS09500	COG0725	ABC transporter, periplasmic molybdate-binding protein
OTEC02_RS09505	COG2005	Transcriptional regulator
OTEC02_RS09510	COG4638	Rieske (2fe-2S)
OTEC02_RS09515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OTEC02_RS09520	COG0543	2 iron, 2 sulfur cluster binding
OTEC02_RS09520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_RS09535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_RS09545	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS09565	COG2207	Transcriptional regulator
OTEC02_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS09575	COG2610	gluconate transmembrane transporter activity
OTEC02_RS09595	COG0583	DNA-binding transcription factor activity
OTEC02_RS09610	COG2031	fatty acid transporter
OTEC02_RS09615	COG0183	Belongs to the thiolase family
OTEC02_RS09620	COG0583	DNA-binding transcription factor activity
OTEC02_RS09625	COG0583	DNA-binding transcription factor activity
OTEC02_RS09640	COG1027	Aspartate ammonia-lyase
OTEC02_RS09650	COG0477	Major facilitator Superfamily
OTEC02_RS09670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_RS09675	COG4521	taurine ABC transporter
OTEC02_RS09690	COG2188	Transcriptional regulator
OTEC02_RS09700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OTEC02_RS09705	COG1733	regulation of RNA biosynthetic process
OTEC02_RS09710	COG3708	Transcriptional regulator
OTEC02_RS09710	COG2207	Transcriptional regulator
OTEC02_RS09725	COG0730	response to heat
OTEC02_RS09745	COG3781	membrane
OTEC02_RS09750	COG1063	alcohol dehydrogenase
OTEC02_RS09760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_RS09765	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_RS09770	COG0022	dehydrogenase e1 component
OTEC02_RS09775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OTEC02_RS09780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OTEC02_RS09795	COG3706	GGDEF domain
OTEC02_RS09815	COG0133	tryptophan synthase activity
OTEC02_RS09825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OTEC02_RS09855	COG0583	DNA-binding transcription factor activity
OTEC02_RS09860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OTEC02_RS09870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OTEC02_RS09925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OTEC02_RS09930	COG4773	Receptor
OTEC02_RS09950	COG0730	response to heat
OTEC02_RS09955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OTEC02_RS09975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OTEC02_RS09995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OTEC02_RS10010	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS10015	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS10020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OTEC02_RS10025	COG2207	Transcriptional regulator
OTEC02_RS10030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OTEC02_RS10035	COG0776	regulation of translation
OTEC02_RS10060	COG0822	iron-sulfur transferase activity
OTEC02_RS10065	COG0316	Belongs to the HesB IscA family
OTEC02_RS10095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OTEC02_RS10115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OTEC02_RS10120	COG0702	epimerase
OTEC02_RS10160	COG0601	transmembrane transport
OTEC02_RS10165	COG0339	signal peptide processing
OTEC02_RS10170	COG4166	transmembrane transport
OTEC02_RS10210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OTEC02_RS10215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OTEC02_RS10230	COG2431	L-lysine efflux transmembrane transporter activity
OTEC02_RS10245	COG0776	regulation of translation
OTEC02_RS10310	COG0084	hydrolase, TatD family'
OTEC02_RS10330	COG1663	tetraacyldisaccharide 4'-kinase activity
OTEC02_RS10335	COG1132	(ABC) transporter
OTEC02_RS10345	COG0811	peptide transport
OTEC02_RS10350	COG1475	DNA binding
OTEC02_RS10355	COG1192	Involved in chromosome partitioning
OTEC02_RS10365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OTEC02_RS10370	COG3178	'Phosphotransferase
OTEC02_RS10380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OTEC02_RS10405	COG0424	maF-like protein
OTEC02_RS10410	COG2850	peptidyl-arginine hydroxylation
OTEC02_RS10420	COG0640	Transcriptional regulator
OTEC02_RS10430	COG3619	membrane
OTEC02_RS10435	COG3122	Protein conserved in bacteria
OTEC02_RS10440	COG1132	(ABC) transporter
OTEC02_RS10460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OTEC02_RS10465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OTEC02_RS10475	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OTEC02_RS10475	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OTEC02_RS10475	COG0506	proline dehydrogenase activity
OTEC02_RS10480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OTEC02_RS10495	COG3698	Phosphodiester glycosidase
OTEC02_RS10505	COG2353	YceI-like domain
OTEC02_RS10515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OTEC02_RS10560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OTEC02_RS10560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OTEC02_RS10585	COG3539	Fimbrial protein
OTEC02_RS10590	COG3121	Chaperone
OTEC02_RS10610	COG0583	DNA-binding transcription factor activity
OTEC02_RS10615	COG0697	spore germination
OTEC02_RS10625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OTEC02_RS10650	COG1309	transcriptional regulator
OTEC02_RS10665	COG1522	sequence-specific DNA binding
OTEC02_RS10675	COG1126	abc transporter atp-binding protein
OTEC02_RS10680	COG0765	amino acid transport
OTEC02_RS10685	COG0765	amino acid transport
OTEC02_RS10715	COG1464	Belongs to the NlpA lipoprotein family
OTEC02_RS10725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OTEC02_RS10730	COG2011	ABC-type metal ion transport system permease component
OTEC02_RS10735	COG0012	GTP binding
OTEC02_RS10755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OTEC02_RS10790	COG2207	Transcriptional regulator
OTEC02_RS10790	COG1917	Cupin 2, conserved barrel domain protein
OTEC02_RS10795	COG0386	Belongs to the glutathione peroxidase family
OTEC02_RS10805	COG0436	Aminotransferase
OTEC02_RS10810	COG1301	dicarboxylic acid transport
OTEC02_RS10845	COG3634	alkyl hydroperoxide reductase activity
OTEC02_RS10860	COG0583	DNA-binding transcription factor activity
OTEC02_RS10865	COG0431	NADPH-dependent FMN reductase
OTEC02_RS10870	COG0798	PFAM Bile acid sodium symporter
OTEC02_RS10880	COG0640	Transcriptional regulator
OTEC02_RS10895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OTEC02_RS10905	COG0583	DNA-binding transcription factor activity
OTEC02_RS10915	COG1953	Uracil, thiamine, allantoin
OTEC02_RS10925	COG2175	clavaminate synthase activity
OTEC02_RS10930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_RS10935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OTEC02_RS10940	COG4521	taurine ABC transporter
OTEC02_RS10950	COG0477	Major facilitator Superfamily
OTEC02_RS10975	COG1271	oxidase subunit
OTEC02_RS10980	COG1294	oxidase, subunit
OTEC02_RS10990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_RS11010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OTEC02_RS11030	COG3052	prosthetic group binding
OTEC02_RS11035	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OTEC02_RS11045	COG0583	DNA-binding transcription factor activity
OTEC02_RS11060	COG2814	Major facilitator Superfamily
OTEC02_RS11080	COG1346	cytolysis
OTEC02_RS11090	COG0583	DNA-binding transcription factor activity
OTEC02_RS11095	COG0625	glutathione transferase activity
OTEC02_RS11100	COG0625	glutathione transferase activity
OTEC02_RS11105	COG0583	DNA-binding transcription factor activity
OTEC02_RS11120	COG1045	serine acetyltransferase
OTEC02_RS11125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OTEC02_RS11130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OTEC02_RS11140	COG1280	lysine exporter protein (LysE YggA)
OTEC02_RS11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OTEC02_RS11160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OTEC02_RS11170	COG0765	amino acid transport
OTEC02_RS11175	COG0765	amino acid transport
OTEC02_RS11195	COG0784	Response regulator, receiver
OTEC02_RS11195	COG2205	protein histidine kinase activity
OTEC02_RS11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OTEC02_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS11280	COG0583	DNA-binding transcription factor activity
OTEC02_RS11295	COG2814	Major facilitator Superfamily
OTEC02_RS11310	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS11315	COG1309	transcriptional regulator
OTEC02_RS11320	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS11325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OTEC02_RS11330	COG1024	Enoyl-CoA hydratase
OTEC02_RS11335	COG4770	biotin carboxylase activity
OTEC02_RS11345	COG0583	DNA-binding transcription factor activity
OTEC02_RS11370	COG2814	Major facilitator Superfamily
OTEC02_RS11380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_RS11385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_RS11390	COG2814	Major facilitator Superfamily
OTEC02_RS11395	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS11400	COG1024	Enoyl-CoA hydratase
OTEC02_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS11415	COG0183	Belongs to the thiolase family
OTEC02_RS11425	COG2814	Major facilitator Superfamily
OTEC02_RS11435	COG1024	Enoyl-CoA hydratase
OTEC02_RS11450	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS11455	COG2814	Major facilitator Superfamily
OTEC02_RS11460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OTEC02_RS11465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OTEC02_RS11480	COG3842	ATPase activity
OTEC02_RS11485	COG1840	ABC-type Fe3 transport system, periplasmic component
OTEC02_RS11500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_RS11505	COG1414	Transcriptional regulator
OTEC02_RS11510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OTEC02_RS11515	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS11525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OTEC02_RS11535	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS11540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OTEC02_RS11575	COG1309	transcriptional regulator
OTEC02_RS11580	COG1309	transcriptional regulator
OTEC02_RS11595	COG0702	epimerase
OTEC02_RS11600	COG1733	regulation of RNA biosynthetic process
OTEC02_RS11605	COG4221	oxidoreductase activity
OTEC02_RS11610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OTEC02_RS11630	COG0300	oxidoreductase activity
OTEC02_RS11640	COG0534	Mate efflux family protein
OTEC02_RS11680	COG2050	protein possibly involved in aromatic compounds catabolism
OTEC02_RS11690	COG3327	negative regulation of DNA-templated transcription, initiation
OTEC02_RS11695	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OTEC02_RS11700	COG0183	Belongs to the thiolase family
OTEC02_RS11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
OTEC02_RS11710	COG1024	Enoyl-CoA hydratase
OTEC02_RS11715	COG1024	Enoyl-CoA hydratase
OTEC02_RS11720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_RS11725	COG2151	metal-sulfur cluster biosynthetic enzyme
OTEC02_RS11730	COG3396	Phenylacetate-CoA oxygenase
OTEC02_RS11735	COG3460	Phenylacetate-CoA oxygenase
OTEC02_RS11740	COG3396	Phenylacetate-CoA oxygenase
OTEC02_RS11745	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS11745	COG2030	dehydratase
OTEC02_RS11750	COG1760	l-serine dehydratase
OTEC02_RS11755	COG0697	spore germination
OTEC02_RS11765	COG0789	Transcriptional regulator
OTEC02_RS11775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OTEC02_RS11780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_RS11795	COG2807	transmembrane transport
OTEC02_RS11800	COG0590	tRNA wobble adenosine to inosine editing
OTEC02_RS11955	COG1116	anion transmembrane transporter activity
OTEC02_RS11970	COG0864	Transcriptional regulator
OTEC02_RS11980	COG1733	regulation of RNA biosynthetic process
OTEC02_RS11985	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_RS11990	COG0439	Biotin carboxylase
OTEC02_RS12005	COG1063	alcohol dehydrogenase
OTEC02_RS12010	COG1250	3-hydroxyacyl-CoA dehydrogenase
OTEC02_RS12080	COG0038	chloride channel
OTEC02_RS12085	COG4770	biotin carboxylase activity
OTEC02_RS12105	COG1914	H( )-stimulated, divalent metal cation uptake system
OTEC02_RS12120	COG1595	DNA-templated transcription, initiation
OTEC02_RS12130	COG3220	belongs to the UPF0276 family
OTEC02_RS12165	COG0598	Magnesium transport protein CorA
OTEC02_RS12200	COG1234	tRNA 3'-trailer cleavage
OTEC02_RS12205	COG1309	transcriptional regulator
OTEC02_RS12235	COG1595	DNA-templated transcription, initiation
OTEC02_RS12240	COG3712	iron ion homeostasis
OTEC02_RS12260	COG0402	S-adenosylhomocysteine deaminase activity
OTEC02_RS12290	COG3038	cytochrome b561
OTEC02_RS12295	COG0753	catalase activity
OTEC02_RS12300	COG1733	regulation of RNA biosynthetic process
OTEC02_RS12335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OTEC02_RS12345	COG4122	O-methyltransferase activity
OTEC02_RS12355	COG0110	maltose O-acetyltransferase activity
OTEC02_RS12375	COG1538	Outer membrane efflux protein
OTEC02_RS12380	COG1137	ATPase activity
OTEC02_RS12385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OTEC02_RS12395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OTEC02_RS12420	COG1476	TRANSCRIPTIONal
OTEC02_RS12455	COG3179	chitinase
OTEC02_RS12555	COG3566	protein conserved in bacteria
OTEC02_RS12570	COG3567	Phage-associated protein, HI1409 family
OTEC02_RS12575	COG5410	chromosome segregation
OTEC02_RS12650	COG3620	sequence-specific DNA binding
OTEC02_RS12725	COG2814	Major facilitator Superfamily
OTEC02_RS12735	COG0668	transmembrane transport
OTEC02_RS12775	COG1309	transcriptional regulator
OTEC02_RS12810	COG2226	methyltransferase
OTEC02_RS12835	COG1278	Cold shock
OTEC02_RS12840	COG1560	Kdo2-lipid A biosynthetic process
OTEC02_RS12845	COG1280	lysine exporter protein (LysE YggA)
OTEC02_RS12885	COG1570	exodeoxyribonuclease VII activity
OTEC02_RS12965	COG2871	sodium ion transport
OTEC02_RS12975	COG0583	DNA-binding transcription factor activity
OTEC02_RS12985	COG4638	Rieske (2fe-2S)
OTEC02_RS12995	COG0633	Ferredoxin
OTEC02_RS12995	COG0543	2 iron, 2 sulfur cluster binding
OTEC02_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS13005	COG3135	benzoate transporter
OTEC02_RS13010	COG2814	Major facilitator Superfamily
OTEC02_RS13025	COG1643	Atp-dependent helicase
OTEC02_RS13050	COG3634	alkyl hydroperoxide reductase activity
OTEC02_RS13070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OTEC02_RS13090	COG0625	glutathione transferase activity
OTEC02_RS13100	COG2885	chlorophyll binding
OTEC02_RS13130	COG1546	Belongs to the CinA family
OTEC02_RS13130	COG1058	Belongs to the CinA family
OTEC02_RS13135	COG0542	response to heat
OTEC02_RS13150	COG1765	OsmC-like protein
OTEC02_RS13165	COG0667	Aldo Keto reductase
OTEC02_RS13180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OTEC02_RS13195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OTEC02_RS13205	COG0527	aspartate kinase activity
OTEC02_RS13215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OTEC02_RS13225	COG3038	cytochrome b561
OTEC02_RS13230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OTEC02_RS13235	COG2252	PERMEase
OTEC02_RS13245	COG1741	Belongs to the pirin family
OTEC02_RS13250	COG1309	transcriptional regulator
OTEC02_RS13260	COG0300	oxidoreductase activity
OTEC02_RS13265	COG2072	flavoprotein involved in K transport
OTEC02_RS13270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OTEC02_RS13275	COG0583	DNA-binding transcription factor activity
OTEC02_RS13290	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OTEC02_RS13320	COG1944	ATP diphosphatase activity
OTEC02_RS13340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_RS13355	COG2814	Major facilitator Superfamily
OTEC02_RS13360	COG1024	Enoyl-CoA hydratase
OTEC02_RS13365	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS13375	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS13400	COG2186	Transcriptional regulator
OTEC02_RS13405	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS13415	COG4948	Mandelate Racemase Muconate Lactonizing
OTEC02_RS13420	COG2271	Major facilitator Superfamily
OTEC02_RS13425	COG2721	sulfolactate sulfo-lyase activity
OTEC02_RS13430	COG0697	spore germination
OTEC02_RS13460	COG1113	amino acid transport
OTEC02_RS13480	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS13500	COG0531	amino acid
OTEC02_RS13510	COG1113	amino acid transport
OTEC02_RS13545	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_RS13545	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_RS13555	COG5001	Diguanylate cyclase
OTEC02_RS13555	COG4251	negative regulation of phosphorylation
OTEC02_RS13555	COG3706	GGDEF domain
OTEC02_RS13555	COG2203	Gaf domain
OTEC02_RS13565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OTEC02_RS13585	COG4172	Belongs to the ABC transporter superfamily
OTEC02_RS13590	COG4239	(ABC) transporter, permease
OTEC02_RS13595	COG4174	ABC transporter (Permease)
OTEC02_RS13600	COG4166	transmembrane transport
OTEC02_RS13605	COG1388	LysM domain
OTEC02_RS13605	COG0741	lytic transglycosylase activity
OTEC02_RS13645	COG0583	DNA-binding transcription factor activity
OTEC02_RS13650	COG1279	arginine transmembrane transporter activity
OTEC02_RS13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_RS13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_RS13680	COG0006	proline dipeptidase activity
OTEC02_RS13720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OTEC02_RS13735	COG3384	dioxygenase
OTEC02_RS13745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OTEC02_RS13750	COG2878	Part of a membrane complex involved in electron transport
OTEC02_RS13755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OTEC02_RS13780	COG0768	penicillin binding
OTEC02_RS13785	COG0742	ribosomal rna small subunit methyltransferase
OTEC02_RS13800	COG0830	nickel cation binding
OTEC02_RS13810	COG0804	urea catabolic process
OTEC02_RS13835	COG3015	lipoprotein NlpE involved in copper resistance
OTEC02_RS13850	COG1253	flavin adenine dinucleotide binding
OTEC02_RS13855	COG2851	Citrate transporter
OTEC02_RS13895	COG1773	rubredoxin
OTEC02_RS13900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_RS13905	COG2267	carboxylic ester hydrolase activity
OTEC02_RS13910	COG0583	DNA-binding transcription factor activity
OTEC02_RS13940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OTEC02_RS13945	COG4181	ATPase activity
OTEC02_RS13970	COG4771	TonB-dependent receptor
OTEC02_RS13990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OTEC02_RS14010	COG0306	phosphate transporter
OTEC02_RS14020	COG3958	Transketolase
OTEC02_RS14025	COG3959	Transketolase, thiamine diphosphate binding domain
OTEC02_RS14030	COG2271	Major facilitator Superfamily
OTEC02_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS14040	COG0583	DNA-binding transcription factor activity
OTEC02_RS14060	COG2223	nitrite transmembrane transporter activity
OTEC02_RS14065	COG2207	Transcriptional regulator
OTEC02_RS14070	COG2066	Belongs to the glutaminase family
OTEC02_RS14075	COG0242	peptide deformylase activity
OTEC02_RS14080	COG0477	Major facilitator Superfamily
OTEC02_RS14095	COG0028	Belongs to the TPP enzyme family
OTEC02_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS14115	COG2267	carboxylic ester hydrolase activity
OTEC02_RS14125	COG2271	Major facilitator Superfamily
OTEC02_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS14160	COG1414	Transcriptional regulator
OTEC02_RS14175	COG1024	Enoyl-CoA hydratase
OTEC02_RS14185	COG1215	transferase activity, transferring glycosyl groups
OTEC02_RS14190	COG1649	PFAM Uncharacterised BCR, COG1649
OTEC02_RS14190	COG0726	polysaccharide deacetylase
OTEC02_RS14200	COG4681	YaeQ
OTEC02_RS14220	COG1607	acyl-coa hydrolase
OTEC02_RS14230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OTEC02_RS14235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OTEC02_RS14240	COG1309	transcriptional regulator
OTEC02_RS14265	COG2040	homocysteine
OTEC02_RS14270	COG0531	amino acid
OTEC02_RS14325	COG1595	DNA-templated transcription, initiation
OTEC02_RS14335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OTEC02_RS14340	COG0477	Major facilitator Superfamily
OTEC02_RS14395	COG0405	Gamma-glutamyltransferase
OTEC02_RS14400	COG2814	Major facilitator Superfamily
OTEC02_RS14410	COG2050	protein possibly involved in aromatic compounds catabolism
OTEC02_RS14425	COG1090	epimerase
OTEC02_RS14445	COG0420	3'-5' exonuclease activity
OTEC02_RS14470	COG0735	belongs to the Fur family
OTEC02_RS14475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OTEC02_RS14480	COG2914	Belongs to the UPF0125 (RnfH) family
OTEC02_RS14500	COG0121	glutamine amidotransferase
OTEC02_RS14515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OTEC02_RS14525	COG0210	DNA helicase
OTEC02_RS14530	COG2885	chlorophyll binding
OTEC02_RS14535	COG0204	Acyl-transferase
OTEC02_RS14550	COG2894	cell division
OTEC02_RS14565	COG1280	lysine exporter protein (LysE YggA)
OTEC02_RS14570	COG1674	ftsk spoiiie
OTEC02_RS14575	COG0492	ferredoxin-NADP+ reductase activity
OTEC02_RS14580	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OTEC02_RS14590	COG0456	acetyltransferase
OTEC02_RS14605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OTEC02_RS14610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OTEC02_RS14620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OTEC02_RS14635	COG1981	membrane
OTEC02_RS14645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OTEC02_RS14645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OTEC02_RS14665	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS14670	COG4638	Rieske (2fe-2S)
OTEC02_RS14675	COG0657	acetylesterase activity
OTEC02_RS14685	COG0473	3-isopropylmalate dehydrogenase activity
OTEC02_RS14690	COG0583	DNA-binding transcription factor activity
OTEC02_RS14710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OTEC02_RS14745	COG0358	DNA primase activity
OTEC02_RS14760	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OTEC02_RS14790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OTEC02_RS14820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OTEC02_RS14830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OTEC02_RS14830	COG0352	thiamine-phosphate diphosphorylase activity
OTEC02_RS14830	COG0351	phosphomethylpyrimidine kinase
OTEC02_RS14835	COG1652	LysM domain
OTEC02_RS14860	COG1399	metal-binding, possibly nucleic acid-binding protein
OTEC02_RS14865	COG3101	peptidyl-lysine hydroxylation
OTEC02_RS14870	COG0009	L-threonylcarbamoyladenylate synthase
OTEC02_RS14875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OTEC02_RS14880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OTEC02_RS14895	COG4106	trans-aconitate 2-methyltransferase activity
OTEC02_RS14910	COG2226	methyltransferase
OTEC02_RS14910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OTEC02_RS14910	COG0596	Alpha beta hydrolase
OTEC02_RS14920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OTEC02_RS14925	COG2223	nitrite transmembrane transporter activity
OTEC02_RS14945	COG1196	nuclear chromosome segregation
OTEC02_RS14955	COG0730	response to heat
OTEC02_RS14970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OTEC02_RS14980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OTEC02_RS15035	COG0489	protein tyrosine kinase activity
OTEC02_RS15045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_RS15045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_RS15080	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OTEC02_RS15085	COG2081	HI0933 family
OTEC02_RS15095	COG0668	transmembrane transport
OTEC02_RS15115	COG0583	DNA-binding transcription factor activity
OTEC02_RS15120	COG1278	Cold shock
OTEC02_RS15135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OTEC02_RS15140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OTEC02_RS15170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OTEC02_RS15195	COG2199	diguanylate cyclase activity
OTEC02_RS15210	COG0745	RESPONSE REGULATOR receiver
OTEC02_RS15225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OTEC02_RS15265	COG0110	maltose O-acetyltransferase activity
OTEC02_RS15270	COG0438	transferase activity, transferring glycosyl groups
OTEC02_RS15325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_RS15340	COG0583	DNA-binding transcription factor activity
OTEC02_RS15375	COG0583	DNA-binding transcription factor activity
OTEC02_RS15395	COG0583	DNA-binding transcription factor activity
OTEC02_RS15400	COG1053	succinate dehydrogenase
OTEC02_RS15415	COG1309	transcriptional regulator
OTEC02_RS15425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OTEC02_RS15430	COG2814	Major facilitator Superfamily
OTEC02_RS15435	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS15440	COG0583	DNA-binding transcription factor activity
OTEC02_RS15445	COG1063	alcohol dehydrogenase
OTEC02_RS15475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OTEC02_RS15480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OTEC02_RS15485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OTEC02_RS15505	COG2132	Multicopper oxidase
OTEC02_RS15515	COG0561	phosphatase activity
OTEC02_RS15520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OTEC02_RS15530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OTEC02_RS15545	COG1214	PFAM Peptidase M22, glycoprotease
OTEC02_RS15605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OTEC02_RS15610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OTEC02_RS15615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OTEC02_RS15675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OTEC02_RS15685	COG1846	Transcriptional regulator
OTEC02_RS15690	COG1764	response to oxidative stress
OTEC02_RS15730	COG0037	tRNA processing
OTEC02_RS15740	COG0248	Ppx GppA phosphatase
OTEC02_RS15770	COG0072	phenylalanine-tRNA ligase activity
OTEC02_RS15800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OTEC02_RS15815	COG1238	metal cluster binding
OTEC02_RS15820	COG0625	glutathione transferase activity
OTEC02_RS15840	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS15845	COG3028	Belongs to the UPF0307 family
OTEC02_RS15850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OTEC02_RS15870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OTEC02_RS15875	COG0617	tRNA 3'-terminal CCA addition
OTEC02_RS15880	COG1555	photosystem II stabilization
OTEC02_RS15885	COG3956	TIGRFAM MazG family protein
OTEC02_RS15895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OTEC02_RS15915	COG5002	protein histidine kinase activity
OTEC02_RS15915	COG2205	protein histidine kinase activity
OTEC02_RS15915	COG0784	Response regulator, receiver
OTEC02_RS15920	COG1024	Enoyl-CoA hydratase
OTEC02_RS15925	COG2084	Dehydrogenase
OTEC02_RS15930	COG3622	Belongs to the hyi family
OTEC02_RS15960	COG0697	spore germination
OTEC02_RS15970	COG2814	Major facilitator Superfamily
OTEC02_RS15975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OTEC02_RS15985	COG0583	DNA-binding transcription factor activity
OTEC02_RS15995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OTEC02_RS16005	COG0084	hydrolase, TatD family'
OTEC02_RS16020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OTEC02_RS16040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OTEC02_RS16045	COG0440	acetolactate synthase activity
OTEC02_RS16050	COG0028	Belongs to the TPP enzyme family
OTEC02_RS16070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_RS16075	COG1136	(ABC) transporter
OTEC02_RS16075	COG0577	efflux transmembrane transporter activity
OTEC02_RS16095	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OTEC02_RS16100	COG1162	GTPase activity
OTEC02_RS16110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OTEC02_RS16120	COG2091	lysine biosynthetic process via aminoadipic acid
OTEC02_RS16130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OTEC02_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS16175	COG2986	histidine ammonia-lyase
OTEC02_RS16185	COG1216	Glycosyl transferase, family 2
OTEC02_RS16200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OTEC02_RS16225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OTEC02_RS16245	COG1426	Protein conserved in bacteria
OTEC02_RS16280	COG0793	Belongs to the peptidase S41A family
OTEC02_RS16295	COG2267	carboxylic ester hydrolase activity
OTEC02_RS16305	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_RS16310	COG3265	gluconokinase activity
OTEC02_RS16320	COG0800	Aldolase
OTEC02_RS16340	COG0280	phosphate acetyltransferase
OTEC02_RS16340	COG0857	belongs to the CobB CobQ family
OTEC02_RS16345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OTEC02_RS16345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OTEC02_RS16365	COG0740	serine-type endopeptidase activity
OTEC02_RS16375	COG4774	siderophore transport
OTEC02_RS16385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OTEC02_RS16395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OTEC02_RS16395	COG2813	Specifically methylates the guanine in position
OTEC02_RS16495	COG0788	formyltetrahydrofolate deformylase activity
OTEC02_RS16520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OTEC02_RS16520	COG4651	solute:proton antiporter activity
OTEC02_RS16540	COG0724	RNA recognition motif
OTEC02_RS16545	COG0210	DNA helicase
OTEC02_RS16570	COG1733	regulation of RNA biosynthetic process
OTEC02_RS16580	COG2900	Belongs to the SlyX family
OTEC02_RS16585	COG0488	(ABC) transporter
OTEC02_RS16595	COG1560	Kdo2-lipid A biosynthetic process
OTEC02_RS16605	COG1301	dicarboxylic acid transport
OTEC02_RS16660	COG0473	3-isopropylmalate dehydrogenase activity
OTEC02_RS16685	COG0583	DNA-binding transcription factor activity
OTEC02_RS16725	COG0583	DNA-binding transcription factor activity
OTEC02_RS16735	COG0625	glutathione transferase activity
OTEC02_RS16740	COG2378	regulation of single-species biofilm formation
OTEC02_RS16745	COG0546	phosphoglycolate phosphatase activity
OTEC02_RS16760	COG1530	ribonuclease E activity
OTEC02_RS16765	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS16780	COG0583	DNA-binding transcription factor activity
OTEC02_RS16785	COG4221	oxidoreductase activity
OTEC02_RS16790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OTEC02_RS16800	COG0534	Mate efflux family protein
OTEC02_RS16815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OTEC02_RS16840	COG0493	'glutamate synthase
OTEC02_RS16850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OTEC02_RS16855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OTEC02_RS16870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OTEC02_RS16880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OTEC02_RS16880	COG0644	oxidoreductase
OTEC02_RS16895	COG4535	Mg2 and Co2 transporter CorC
OTEC02_RS16905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_RS16905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_RS16925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OTEC02_RS16935	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OTEC02_RS16945	COG0484	heat shock protein binding
OTEC02_RS16950	COG0789	Transcriptional regulator
OTEC02_RS16955	COG0598	Magnesium transport protein CorA
OTEC02_RS16960	COG1185	polyribonucleotide nucleotidyltransferase activity
OTEC02_RS16970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OTEC02_RS16975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OTEC02_RS16980	COG1074	ATP-dependent DNA helicase activity
OTEC02_RS16985	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OTEC02_RS17005	COG2226	methyltransferase
OTEC02_RS17015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OTEC02_RS17025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OTEC02_RS17040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OTEC02_RS17040	COG2111	Na H antiporter
OTEC02_RS17045	COG1006	Multisubunit Na H antiporter MnhC subunit
OTEC02_RS17050	COG0651	ATP synthesis coupled electron transport
OTEC02_RS17055	COG1863	multisubunit Na H antiporter MnhE subunit
OTEC02_RS17060	COG2212	antiporter activity
OTEC02_RS17065	COG1320	monovalent cation:proton antiporter activity
OTEC02_RS17070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OTEC02_RS17080	COG0195	Participates in both transcription termination and antitermination
OTEC02_RS17130	COG0237	dephospho-CoA kinase activity
OTEC02_RS17140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OTEC02_RS17155	COG0497	DNA recombination
OTEC02_RS17165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OTEC02_RS17200	COG2169	Transcriptional regulator
OTEC02_RS17200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OTEC02_RS17205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OTEC02_RS17275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OTEC02_RS17290	COG0326	Molecular chaperone. Has ATPase activity
OTEC02_RS17305	COG2056	Na+-H+ antiporter family
OTEC02_RS17375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OTEC02_RS17405	COG0546	phosphoglycolate phosphatase activity
OTEC02_RS17410	COG1716	ATPase activity
OTEC02_RS17455	COG0181	hydroxymethylbilane synthase activity
OTEC02_RS17465	COG3275	phosphorelay sensor kinase activity
OTEC02_RS17485	COG1538	Outer membrane efflux protein
OTEC02_RS17495	COG0697	spore germination
OTEC02_RS17515	COG0494	nUDIX hydrolase
OTEC02_RS17520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OTEC02_RS17525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OTEC02_RS17530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OTEC02_RS17535	COG0772	Belongs to the SEDS family
OTEC02_RS17560	COG4974	Belongs to the 'phage' integrase family
OTEC02_RS17565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OTEC02_RS17575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OTEC02_RS17585	COG2197	response regulator
OTEC02_RS17600	COG0793	Belongs to the peptidase S41A family
OTEC02_RS17605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OTEC02_RS17610	COG0795	lipopolysaccharide-transporting ATPase activity
OTEC02_RS17615	COG0795	lipopolysaccharide-transporting ATPase activity
OTEC02_RS17650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OTEC02_RS17650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OTEC02_RS17660	COG0004	ammonium transporteR
OTEC02_RS17665	COG0347	Belongs to the P(II) protein family
OTEC02_RS17675	COG0606	chelatase, subunit chli
OTEC02_RS17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_RS17690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OTEC02_RS17710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OTEC02_RS17725	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS17735	COG0477	Major facilitator Superfamily
OTEC02_RS17740	COG2860	membrane
OTEC02_RS17750	COG1253	flavin adenine dinucleotide binding
OTEC02_RS17765	COG2814	Major facilitator Superfamily
OTEC02_RS17775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OTEC02_RS17810	COG0655	NAD(P)H dehydrogenase (quinone) activity
OTEC02_RS17820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OTEC02_RS17855	COG1309	transcriptional regulator
OTEC02_RS17890	COG0758	DNA mediated transformation
OTEC02_RS17900	COG0697	spore germination
OTEC02_RS17905	COG1309	transcriptional regulator
OTEC02_RS17920	COG0386	Belongs to the glutathione peroxidase family
OTEC02_RS17940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OTEC02_RS17950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OTEC02_RS17990	COG1121	(ABC) transporter
OTEC02_RS17995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OTEC02_RS18000	COG1280	lysine exporter protein (LysE YggA)
OTEC02_RS18005	COG2837	iron assimilation
OTEC02_RS18010	COG0281	malic enzyme
OTEC02_RS18060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OTEC02_RS18060	COG0519	Catalyzes the synthesis of GMP from XMP
OTEC02_RS18065	COG4399	Belongs to the UPF0754 family
OTEC02_RS18070	COG2259	Doxx family
OTEC02_RS18075	COG0586	Pfam SNARE associated Golgi protein
OTEC02_RS18090	COG1192	Involved in chromosome partitioning
OTEC02_RS18100	COG0271	Belongs to the BolA IbaG family
OTEC02_RS18140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OTEC02_RS18140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OTEC02_RS18140	COG3321	synthase
OTEC02_RS18140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OTEC02_RS18145	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS18150	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_RS18155	COG2197	response regulator
OTEC02_RS18165	COG3916	Acyl-homoserine-lactone synthase
OTEC02_RS18170	COG0477	Major facilitator Superfamily
OTEC02_RS18175	COG1024	Enoyl-CoA hydratase
OTEC02_RS18180	COG1024	Enoyl-CoA hydratase
OTEC02_RS18185	COG1960	acyl-CoA dehydrogenase activity
OTEC02_RS18190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OTEC02_RS18230	COG1113	amino acid transport
OTEC02_RS18235	COG1113	amino acid transport
OTEC02_RS18240	COG0251	oxidation-reduction process
OTEC02_RS18280	COG0564	pseudouridine synthase activity
OTEC02_RS18360	COG1051	belongs to the nudix hydrolase family
OTEC02_RS18380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OTEC02_RS18395	COG1802	Transcriptional regulator
OTEC02_RS18405	COG1448	Aminotransferase
OTEC02_RS18420	COG2186	Transcriptional regulator
OTEC02_RS18430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OTEC02_RS18435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OTEC02_RS18450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OTEC02_RS18460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OTEC02_RS18470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OTEC02_RS18480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OTEC02_RS18510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OTEC02_RS18540	COG0728	peptidoglycan biosynthetic process
OTEC02_RS18545	COG3023	N-Acetylmuramoyl-L-alanine amidase
OTEC02_RS18580	COG1017	nitric oxide dioxygenase activity
OTEC02_RS18580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_RS18605	COG0546	phosphoglycolate phosphatase activity
OTEC02_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_RS18625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OTEC02_RS18625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OTEC02_RS18630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_RS18635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_RS18640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OTEC02_RS18645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_RS18650	COG1116	anion transmembrane transporter activity
OTEC02_RS18655	COG1309	transcriptional regulator
OTEC02_RS18660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OTEC02_RS18670	COG0196	riboflavin kinase activity
OTEC02_RS18675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OTEC02_RS18685	COG1047	Peptidyl-prolyl cis-trans
OTEC02_RS18725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OTEC02_RS18730	COG0657	acetylesterase activity
OTEC02_RS18780	COG2951	lytic endotransglycosylase activity
OTEC02_RS18785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OTEC02_RS18800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OTEC02_RS18810	COG0671	phosphoesterase, PA-phosphatase related
OTEC02_RS18815	COG0861	Integral membrane protein TerC family
OTEC02_RS18830	COG0754	glutathionylspermidine amidase activity
OTEC02_RS18840	COG0402	S-adenosylhomocysteine deaminase activity
OTEC02_RS18855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OTEC02_RS18860	COG1230	cation diffusion facilitator family transporter
OTEC02_RS18875	COG0706	membrane insertase activity