locus-tag	class	description
HLV59_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLV59_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLV59_RS00035	ENOG4105C5H	ABC transporter
HLV59_RS00040	ENOG4108821	RND type efflux pump
HLV59_RS00045	ENOG4108821	RND type efflux pump
HLV59_RS00050	ENOG4108821	RND type efflux pump
HLV59_RS00060	ENOG4105D74	hydrolase
HLV59_RS00065	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HLV59_RS00070	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HLV59_RS00110	ENOG4105C8J	)-transporter
HLV59_RS00120	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HLV59_RS00150	ENOG4105C2W	permease
HLV59_RS00160	ENOG4108IG5	Transcriptional regulator
HLV59_RS00165	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HLV59_RS00200	ENOG4105F27	Major Facilitator
HLV59_RS00205	ENOG4105CV8	reductase
HLV59_RS00210	ENOG4105HEI	LysR family (Transcriptional regulator
HLV59_RS00230	ENOG4105DQ4	alcohol dehydrogenase
HLV59_RS00235	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HLV59_RS00250	ENOG4105CEN	a g-specific adenine glycosylase
HLV59_RS00270	ENOG4108ZZ3	UPF0260 protein
HLV59_RS00275	ENOG4105D8V	Glucose sorbosone dehydrogenase
HLV59_RS00280	ENOG4105D1H	recombination factor protein RarA
HLV59_RS00285	ENOG4105S64	Formate nitrite transporter
HLV59_RS00305	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLV59_RS00310	ENOG4108RWI	nicotinamidase
HLV59_RS00315	ENOG4105C09	Bile acid
HLV59_RS00320	ENOG4105UQX	Mate efflux family protein
HLV59_RS00325	ENOG4105EWC	Purine nucleoside phosphorylase
HLV59_RS00340	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HLV59_RS00345	ENOG4108RXX	maleylacetoacetate isomerase
HLV59_RS00355	ENOG4105C85	amino acid
HLV59_RS00365	ENOG4105CKI	cobalamin synthesis protein
HLV59_RS00375	ENOG4105CZE	histidine utilization repressor
HLV59_RS00380	ENOG41090B9	response to stress
HLV59_RS00395	ENOG4105C85	amino acid
HLV59_RS00405	ENOG41088SP	formiminoglutamate hydrolase
HLV59_RS00415	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
HLV59_RS00420	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLV59_RS00435	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLV59_RS00445	ENOG4108ZAI	phosphatidylglycerophosphatase a
HLV59_RS00450	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HLV59_RS00465	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HLV59_RS00500	ENOG4105KHC	sulfurtransferase
HLV59_RS00530	ENOG4105BZU	Histidine kinase
HLV59_RS00535	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLV59_RS00550	ENOG4107QJQ	Mate efflux family protein
HLV59_RS00555	ENOG4105CHM	Aminotransferase
HLV59_RS00560	ENOG4106BRA	Membrane
HLV59_RS00575	ENOG4105D9M	gamma-glutamylcysteine synthetase
HLV59_RS00585	ENOG4105CS6	Rhs element vgr protein
HLV59_RS00610	ENOG4105IPS	esterase
HLV59_RS00615	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLV59_RS00620	ENOG4108Z2U	ureidoglycolate hydrolase
HLV59_RS00630	ENOG41061H0	Monooxygenase
HLV59_RS00675	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HLV59_RS00680	ENOG4105BZU	Histidine kinase
HLV59_RS00695	ENOG4105KUZ	arsenate reductase
HLV59_RS00700	ENOG4105CGK	Exodeoxyribonuclease III
HLV59_RS00730	ENOG4105D7Z	glutathione synthase
HLV59_RS00750	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HLV59_RS00755	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HLV59_RS00760	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HLV59_RS00775	ENOG41063SB	peptidase
HLV59_RS00780	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HLV59_RS00785	ENOG4107QSN	dihydrolipoamide acetyltransferase
HLV59_RS00800	ENOG4105E0K	tonB-dependent siderophore receptor
HLV59_RS00810	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLV59_RS00825	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HLV59_RS00850	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS00855	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HLV59_RS00865	ENOG4105D64	Mechanosensitive ion channel
HLV59_RS00875	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HLV59_RS00880	ENOG4108W2Y	isochorismatase
HLV59_RS00890	ENOG4105FBW	Monooxygenase
HLV59_RS00895	ENOG4108UZX	fmn reductase
HLV59_RS00910	ENOG4105BZU	Histidine kinase
HLV59_RS00915	ENOG41062QD	Membrane
HLV59_RS00920	ENOG4107QN1	sodium solute
HLV59_RS00930	ENOG4105C94	Transporter
HLV59_RS00940	ENOG4105BZU	Histidine kinase
HLV59_RS00945	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HLV59_RS00950	ENOG4108WUH	Transcriptional regulator, TetR family
HLV59_RS00965	ENOG4105RA2	Membrane
HLV59_RS00970	ENOG4108IXY	short-chain dehydrogenase reductase
HLV59_RS00980	ENOG4105DWF	phosphomethylpyrimidine kinase
HLV59_RS00990	ENOG4107RDB	Major Facilitator
HLV59_RS00995	ENOG4108UUM	single-stranded DNA-binding protein
HLV59_RS01005	ENOG4108UMN	azlc family
HLV59_RS01025	ENOG4108JPW	Aminotransferase
HLV59_RS01030	ENOG4105C26	Dehydrogenase
HLV59_RS01040	ENOG4105CHJ	isochorismatase hydrolase
HLV59_RS01045	ENOG4105EUB	pirin domain protein
HLV59_RS01120	ENOG4105CPC	Aldo Keto reductase
HLV59_RS01125	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HLV59_RS01130	ENOG4105R8C	Transcriptional regulator
HLV59_RS01155	ENOG4105KVH	Transcriptional regulator
HLV59_RS01160	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HLV59_RS01190	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HLV59_RS01245	ENOG4105CUV	Homoserine Kinase
HLV59_RS01260	ENOG410631K	Membrane
HLV59_RS01270	ENOG41083J0	(ABC) transporter
HLV59_RS01290	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HLV59_RS01315	ENOG4108R6G	acetyltransferase
HLV59_RS01320	ENOG4105CYC	Transferase
HLV59_RS01330	ENOG4105E0F	Histidine kinase
HLV59_RS01345	ENOG4105CHH	sulfate transporter
HLV59_RS01350	ENOG4105PDP	Short chain dehydrogenase
HLV59_RS01360	ENOG4105C5H	ABC transporter
HLV59_RS01440	ENOG4108IQI	permease
HLV59_RS01465	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HLV59_RS01480	ENOG4105CJN	penicillin-binding protein
HLV59_RS01485	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HLV59_RS01490	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HLV59_RS01505	ENOG4105DHI	Methyltransferase
HLV59_RS01510	ENOG4108JQC	penicillin-binding protein 1A
HLV59_RS01535	ENOG4105E4G	Type IV pilus
HLV59_RS01555	ENOG4105CBC	glutamate synthase
HLV59_RS01560	ENOG4105BZ8	glutamate synthase
HLV59_RS01570	ENOG4108V0P	LemA family
HLV59_RS01575	ENOG4105HA9	of methanol dehydrogenase type
HLV59_RS01595	ENOG4108YSG	O-Antigen polymerase
HLV59_RS01600	ENOG4108UQY	Iron-storage protein
HLV59_RS01610	ENOG4105KME	endoribonuclease L-psp
HLV59_RS01615	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HLV59_RS01630	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HLV59_RS01680	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HLV59_RS01690	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HLV59_RS01695	ENOG4107IFA	Lipase (EC 3.1.1.3)
HLV59_RS01700	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
HLV59_RS01705	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HLV59_RS01725	ENOG4107AQZ	Membrane
HLV59_RS01730	ENOG4108JQ1	Dehydrogenase
HLV59_RS01735	ENOG4105CQB	FAD linked oxidase domain protein
HLV59_RS01745	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HLV59_RS01750	ENOG4105NF4	modulator of drug activity
HLV59_RS01760	ENOG4107QF7	multi-drug
HLV59_RS01765	ENOG4105EM2	membrane
HLV59_RS01770	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLV59_RS01775	ENOG4105IPI	Membrane
HLV59_RS01780	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HLV59_RS01810	ENOG4108IQI	permease
HLV59_RS01815	ENOG4105D82	Glutamate dehydrogenase
HLV59_RS01820	ENOG4105C8Y	Acetylornithine aminotransferase
HLV59_RS01830	ENOG4105C26	Dehydrogenase
HLV59_RS01855	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLV59_RS01895	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HLV59_RS01925	ENOG41067S9	phage shock protein C, PspC
HLV59_RS01935	ENOG4105CSU	acyl-Coa dehydrogenase
HLV59_RS01950	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HLV59_RS01965	ENOG4105ECY	inositol monophosphatase
HLV59_RS01970	ENOG4105C1J	atp-dependent rna helicase
HLV59_RS01980	ENOG4105DHJ	ABC, transporter
HLV59_RS01985	ENOG4105CY3	ABC transporter, permease
HLV59_RS01995	ENOG4105E3I	toluene tolerance
HLV59_RS02005	ENOG4105D7N	magnesium and cobalt transport protein CorA
HLV59_RS02010	ENOG4108URH	decarboxylase
HLV59_RS02020	ENOG4105MJ2	Competence protein
HLV59_RS02025	ENOG4105CB5	ATP-dependent DNA helicase recG
HLV59_RS02040	ENOG4105E55	glycerol-3-phosphate acyltransferase
HLV59_RS02045	ENOG4105C29	acyl-CoA thioesterase
HLV59_RS02050	ENOG4105CK2	sodium dicarboxylate symporter
HLV59_RS02065	ENOG4105KPV	Transcriptional regulator
HLV59_RS02080	ENOG4105D7A	ATP-binding protein
HLV59_RS02090	ENOG41089BK	Glutamine amido-transferase
HLV59_RS02100	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HLV59_RS02105	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HLV59_RS02200	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HLV59_RS02240	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS02275	ENOG4105VKU	nucleicacid-binding protein
HLV59_RS02280	ENOG4105DGW	oligopeptidase A
HLV59_RS02285	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HLV59_RS02330	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HLV59_RS02335	ENOG4107S2Z	UPF0761 membrane protein
HLV59_RS02340	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HLV59_RS02370	ENOG4105C9A	Phoh family
HLV59_RS02380	ENOG4105E4C	Lytic transglycosylase catalytic
HLV59_RS02410	ENOG4105D6S	protein involved in catabolism of external DNA
HLV59_RS02415	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HLV59_RS02460	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS02470	ENOG4108RZE	Tetr family transcriptional regulator
HLV59_RS02485	ENOG4107QX3	carboxylase
HLV59_RS02490	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS02510	ENOG4105KB2	stringent starvation protein b
HLV59_RS02515	ENOG4107MKT	Stringent starvation protein a
HLV59_RS02520	ENOG4108UJD	30S ribosomal protein S9
HLV59_RS02525	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HLV59_RS02530	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HLV59_RS02535	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HLV59_RS02540	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HLV59_RS02560	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HLV59_RS02570	ENOG4107RZC	phospholipase d
HLV59_RS02585	ENOG4108KHX	Diguanylate cyclase
HLV59_RS02590	ENOG4108WS1	
HLV59_RS02630	ENOG4107QN2	dihydrolipoyl dehydrogenase
HLV59_RS02645	ENOG4107U2T	alpha beta
HLV59_RS02655	ENOG4105NAU	thioesterase Superfamily protein
HLV59_RS02690	ENOG4105K9H	YciI-like protein
HLV59_RS02705	ENOG4105FFC	UPF0187 protein
HLV59_RS02715	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HLV59_RS02720	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HLV59_RS02725	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HLV59_RS02730	ENOG4105VIE	preprotein translocase, subunit YajC
HLV59_RS02750	ENOG4105BZU	Histidine kinase
HLV59_RS02755	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HLV59_RS02760	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HLV59_RS02775	ENOG4107BJW	polysaccharide deacetylase
HLV59_RS02785	ENOG4108PQP	glycosyl transferase group 1
HLV59_RS02820	ENOG4105UGU	tonB-dependent Receptor
HLV59_RS02845	ENOG4108K3A	Glutathione S-transferase
HLV59_RS02850	ENOG4105EQ2	LysR family Transcriptional regulator
HLV59_RS02855	ENOG4105CSU	acyl-Coa dehydrogenase
HLV59_RS02860	ENOG4105CSU	acyl-Coa dehydrogenase
HLV59_RS02870	ENOG4105EB3	Histidine kinase
HLV59_RS02875	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HLV59_RS02885	ENOG4105CNG	UPF0061 protein
HLV59_RS02905	ENOG4108WBT	adenosyltransferase
HLV59_RS02910	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HLV59_RS02955	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HLV59_RS02980	ENOG4105D3R	alkyl hydroperoxide reductase
HLV59_RS02995	ENOG4105CSH	Transporter
HLV59_RS03000	ENOG4108UT2	hemolysin iii
HLV59_RS03010	ENOG41082BV	acetyltransferase
HLV59_RS03030	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS03035	ENOG4108R6W	Transcriptional regulator, ARAC family
HLV59_RS03045	ENOG4105TW1	Carbohydrate-selective porin OprB
HLV59_RS03050	ENOG4105DZG	Dehydrogenase
HLV59_RS03055	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HLV59_RS03075	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS03085	ENOG4108WHA	ompa motb domain protein
HLV59_RS03095	ENOG4105E0Y	RtcB Protein
HLV59_RS03100	ENOG4108IQI	permease
HLV59_RS03110	ENOG4105C2W	permease
HLV59_RS03115	ENOG4105CI3	gtp-binding protein typa
HLV59_RS03130	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HLV59_RS03140	ENOG4108VX5	3-methyladenine DNA glycosylase
HLV59_RS03145	ENOG4105CHB	tonB-dependent Receptor
HLV59_RS03150	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS03155	ENOG4108N2Y	auxin Efflux
HLV59_RS03165	ENOG4105T95	Thiol disulfide interChange protein
HLV59_RS03170	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HLV59_RS03185	ENOG4105K78	MarR family Transcriptional regulator
HLV59_RS03190	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HLV59_RS03195	ENOG4105KWI	UPF0339 protein
HLV59_RS03220	ENOG4108UNF	response regulator
HLV59_RS03225	ENOG4105M3Z	response regulator
HLV59_RS03230	ENOG4108ZGA	chew protein
HLV59_RS03235	ENOG4105C8Q	Methyl-accepting chemotaxis
HLV59_RS03240	ENOG4105CBS	Chea signal transduction histidine kinase
HLV59_RS03250	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLV59_RS03265	ENOG4107PEH	Entericidin EcnA/B family
HLV59_RS03275	ENOG4105WD1	Membrane
HLV59_RS03280	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HLV59_RS03330	ENOG4105EM2	membrane
HLV59_RS03335	ENOG4105C2C	drug resistance transporter, Bcr CflA
HLV59_RS03355	ENOG4105BZG	amino acid carrier protein
HLV59_RS03360	ENOG4105D78	K07001 NTE family protein
HLV59_RS03365	ENOG4105C7B	Threonine dehydratase
HLV59_RS03395	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HLV59_RS03405	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HLV59_RS03415	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HLV59_RS03420	ENOG4105VQ7	Rod shape-determining protein MreD
HLV59_RS03425	ENOG4108Z03	MAF-like protein
HLV59_RS03430	ENOG4105C03	ribonuclease
HLV59_RS03440	ENOG4105D8T	Acyltransferase
HLV59_RS03450	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HLV59_RS03460	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HLV59_RS03485	ENOG4105CF7	AraC family transcriptional regulator
HLV59_RS03510	ENOG4105C85	amino acid
HLV59_RS03515	ENOG4105C7F	AcnD-accessory protein PrpF
HLV59_RS03520	ENOG4105CTB	Polyprenyl synthetase
HLV59_RS03525	ENOG4105MSB	protein, conserved in bacteria
HLV59_RS03540	ENOG4105D78	K07001 NTE family protein
HLV59_RS03565	ENOG4105DIJ	Phosphoethanolamine transferase
HLV59_RS03570	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HLV59_RS03575	ENOG4105DHQ	Histidine kinase
HLV59_RS03590	ENOG4108M0I	Transcriptional regulator
HLV59_RS03610	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HLV59_RS03630	ENOG4108115	UPF0145 protein
HLV59_RS03635	ENOG4105K8R	UPF0145 protein
HLV59_RS03640	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HLV59_RS03645	ENOG4105BZS	acriflavin resistance protein
HLV59_RS03650	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HLV59_RS03655	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HLV59_RS03680	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HLV59_RS03695	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HLV59_RS03700	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HLV59_RS03735	ENOG4105CUB	amino acid
HLV59_RS03750	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HLV59_RS03755	ENOG41084BA	UPF0250 protein
HLV59_RS03760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLV59_RS03795	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HLV59_RS03800	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HLV59_RS03810	ENOG4105E33	succinate dehydrogenase
HLV59_RS03825	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HLV59_RS03830	ENOG4105C7S	Dehydrogenase
HLV59_RS03835	ENOG4107QN2	dihydrolipoyl dehydrogenase
HLV59_RS03845	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HLV59_RS03855	ENOG4105CKW	Inner membrane protein yedI
HLV59_RS03860	ENOG4105CGZ	zinc metallopeptidase
HLV59_RS03865	ENOG4105EEQ	Na H antiporter
HLV59_RS03880	ENOG4105PNM	synthesis protein
HLV59_RS03895	ENOG41080TK	Universal stress protein
HLV59_RS03910	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HLV59_RS03915	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HLV59_RS03935	ENOG4105HBR	Rna-binding protein
HLV59_RS03945	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HLV59_RS03950	ENOG4105EEI	dihydropteroate synthase
HLV59_RS04000	ENOG4105CSH	Transporter
HLV59_RS04005	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HLV59_RS04010	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HLV59_RS04025	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HLV59_RS04045	ENOG41080IJ	Diacylglycerol kinase
HLV59_RS04055	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HLV59_RS04060	ENOG4105BZS	acriflavin resistance protein
HLV59_RS04075	ENOG4105E4C	Lytic transglycosylase catalytic
HLV59_RS04090	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HLV59_RS04095	ENOG4108RRZ	Transcription elongation factor GreB
HLV59_RS04110	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HLV59_RS04120	ENOG4108IND	Tetr family transcriptional regulator
HLV59_RS04125	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS04130	ENOG4107TTQ	Alpha beta hydrolase fold
HLV59_RS04135	ENOG4107TTQ	Alpha beta hydrolase fold
HLV59_RS04140	ENOG4105CPT	Alpha beta hydrolase
HLV59_RS04145	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HLV59_RS04150	ENOG4105CC0	LysR family Transcriptional regulator
HLV59_RS04155	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HLV59_RS04160	ENOG4105C26	Dehydrogenase
HLV59_RS04180	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HLV59_RS04185	ENOG4105BZS	acriflavin resistance protein
HLV59_RS04205	ENOG4105BZW	Glycerate kinase
HLV59_RS04210	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HLV59_RS04215	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HLV59_RS04230	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HLV59_RS04240	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HLV59_RS04245	ENOG4105BZG	amino acid carrier protein
HLV59_RS04250	ENOG4105C85	amino acid
HLV59_RS04260	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HLV59_RS04270	ENOG4105N14	lysine exporter protein LysE YggA
HLV59_RS04275	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLV59_RS04280	ENOG4105BZJ	Electron transfer flavoprotein
HLV59_RS04285	ENOG4105C10	Electron transfer flavoprotein
HLV59_RS04290	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLV59_RS04305	ENOG4107KET	secretion protein, HlyD family
HLV59_RS04340	ENOG4105D60	lipoprotein releasing system transmembrane protein
HLV59_RS04345	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HLV59_RS04350	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HLV59_RS04360	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HLV59_RS04365	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HLV59_RS04370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HLV59_RS04380	ENOG4105C02	permease
HLV59_RS04430	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HLV59_RS04435	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HLV59_RS04445	ENOG4105M8F	Biopolymer transport protein exbD tolR
HLV59_RS04450	ENOG4105E02	MotA TolQ exbB proton channel
HLV59_RS04455	ENOG4107YD3	Thioesterase
HLV59_RS04460	ENOG4105CH2	amidohydrolase
HLV59_RS04480	ENOG4108ETH	Formylglycinamide ribotide synthetase
HLV59_RS04485	ENOG4105C2C	drug resistance transporter, Bcr CflA
HLV59_RS04490	ENOG4105EGD	dinuclear metal center protein, YbgI family
HLV59_RS04495	ENOG4108UKI	Enoyl-CoA hydratase
HLV59_RS04515	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLV59_RS04530	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HLV59_RS04535	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HLV59_RS04550	ENOG4107R11	Transcriptional regulator
HLV59_RS04555	ENOG4108IJ6	ABC transporter
HLV59_RS04565	ENOG4108I5D	sulfate abc transporter
HLV59_RS04575	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HLV59_RS04580	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HLV59_RS04585	ENOG4105HHA	aminodeoxychorismate lyase
HLV59_RS04600	ENOG4108IYU	L-aspartate oxidase
HLV59_RS04605	ENOG4105C0H	protease
HLV59_RS04615	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HLV59_RS04620	ENOG4105C3F	Signal peptidase i
HLV59_RS04630	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HLV59_RS04635	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HLV59_RS04645	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HLV59_RS04650	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HLV59_RS04655	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HLV59_RS04660	ENOG4105EMU	Dehydrogenase
HLV59_RS04700	ENOG4105BZU	Histidine kinase
HLV59_RS04710	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HLV59_RS04720	ENOG4105DTR	rard protein
HLV59_RS04755	ENOG4107QS8	(LipO)protein
HLV59_RS04760	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HLV59_RS04765	ENOG4105EA8	2-Nitropropane dioxygenase
HLV59_RS04790	ENOG4107R8N	Glycosyl transferase, family 2
HLV59_RS04805	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HLV59_RS04810	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HLV59_RS04815	ENOG4105CEP	NADH dehydrogenase
HLV59_RS04820	ENOG4105DZ1	carboxypeptidase
HLV59_RS04830	ENOG4105E9K	Isocitrate dehydrogenase
HLV59_RS04835	ENOG4108R99	pseudouridine synthase
HLV59_RS04850	ENOG4105CBP	Major Facilitator
HLV59_RS04855	ENOG4105EGI	Transcriptional regulator
HLV59_RS04860	ENOG4108ETY	sodium dicarboxylate symporter
HLV59_RS04865	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HLV59_RS04895	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HLV59_RS04910	ENOG4105D3G	Pseudouridine synthase
HLV59_RS04915	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HLV59_RS04930	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HLV59_RS04955	ENOG4108JPW	Aminotransferase
HLV59_RS04960	ENOG4105DY8	decarboxylase
HLV59_RS04970	ENOG4105F7P	transcriptional regulator AsnC family
HLV59_RS04975	ENOG4107RA9	decarboxylase
HLV59_RS04980	ENOG4105C85	amino acid
HLV59_RS04985	ENOG4105CVA	phosphate
HLV59_RS04990	ENOG4105C8U	phosphate abc transporter
HLV59_RS05000	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HLV59_RS05005	ENOG4105ERU	peptidase
HLV59_RS05020	ENOG4107QTF	adenylosuccinate lyase
HLV59_RS05040	ENOG4108Z0R	Transferase
HLV59_RS05045	ENOG4105DZ1	carboxypeptidase
HLV59_RS05065	ENOG4108K5P	(LipO)protein
HLV59_RS05070	ENOG4105EJC	lysr family transcriptional regulator
HLV59_RS05075	ENOG4105DAN	ATP-dependent protease
HLV59_RS05080	ENOG4105EYM	Major Facilitator superfamily
HLV59_RS05090	ENOG4105DHU	Bile acid
HLV59_RS05110	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HLV59_RS05115	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HLV59_RS05120	ENOG4105D22	carbon starvation protein
HLV59_RS05125	ENOG4105VCD	cytoplasmic protein
HLV59_RS05135	ENOG4105DFP	Integrase
HLV59_RS05190	ENOG4105ETT	transcriptional Regulator, LysR family
HLV59_RS05195	ENOG4105H1N	peptidase, M24
HLV59_RS05200	ENOG4105C94	Transporter
HLV59_RS05205	ENOG4105C94	Transporter
HLV59_RS05220	ENOG4107QZF	nitrite reductase NADPH large subunit
HLV59_RS05240	ENOG4105CHR	reductase
HLV59_RS05260	ENOG41060M8	Pfam:PhdYeFM
HLV59_RS05285	ENOG4105C2I	pirin domain protein
HLV59_RS05300	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS05315	ENOG4108IPW	abc transporter atp-binding protein
HLV59_RS05335	ENOG4105C0W	non-ribosomal peptide synthetase
HLV59_RS05340	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HLV59_RS05345	ENOG4105WQI	isochorismatase
HLV59_RS05360	ENOG4105BZ1	(ABC) transporter
HLV59_RS05365	ENOG4108JJ7	ABC transporter
HLV59_RS05380	ENOG4105E4F	Isochorismate synthase
HLV59_RS05395	ENOG4105NX3	Membrane
HLV59_RS05415	ENOG4105EUJ	GTP cyclohydrolase i
HLV59_RS05425	ENOG4105C7W	Xanthine dehydrogenase
HLV59_RS05450	ENOG4105DDQ	anthranilate synthase
HLV59_RS05465	ENOG4105DUX	Transporter
HLV59_RS05480	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HLV59_RS05515	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLV59_RS05520	ENOG4107QNR	UPF0135 protein
HLV59_RS05525	ENOG4105C0H	protease
HLV59_RS05535	ENOG4105C6K	Malic enzyme
HLV59_RS05540	ENOG4105BZU	Histidine kinase
HLV59_RS05545	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HLV59_RS05550	ENOG4105SYT	Methylenetetrahydrofolate reductase
HLV59_RS05555	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HLV59_RS05570	ENOG4107QPN	acyl-Coa dehydrogenase
HLV59_RS05575	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HLV59_RS05580	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HLV59_RS05590	ENOG4107RNU	major facilitator superfamily MFS_1
HLV59_RS05600	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLV59_RS05605	ENOG4105CE9	30S ribosomal protein S2
HLV59_RS05645	ENOG4105CVE	Lytic murein transglycosylase
HLV59_RS05650	ENOG4105CNI	cell division protein FtsW
HLV59_RS05665	ENOG4105E3A	(ABC) transporter
HLV59_RS05670	ENOG4105DA5	(ABC) transporter
HLV59_RS05835	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HLV59_RS05845	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HLV59_RS05855	ENOG4105E89	ABC transporter
HLV59_RS05860	ENOG4105DSP	amino acid AbC transporter
HLV59_RS05865	ENOG4106YG3	ABC transporter
HLV59_RS05870	ENOG4108JEH	abc transporter atp-binding protein
HLV59_RS05880	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HLV59_RS05885	ENOG4105CFP	Peptidase U32
HLV59_RS05890	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLV59_RS05895	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HLV59_RS05900	ENOG4105DP0	ferredoxin-NADP reductase
HLV59_RS05905	ENOG4108R96	Methyltransferase, YaeB family
HLV59_RS05915	ENOG4107QHF	type ii secretion system protein e
HLV59_RS05925	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HLV59_RS05930	ENOG4105DHQ	Histidine kinase
HLV59_RS05940	ENOG4105M6F	mutator MutT protein
HLV59_RS05950	ENOG4105BZ4	penicillin-binding protein
HLV59_RS05955	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HLV59_RS05960	ENOG4105VUT	cytoplasmic protein
HLV59_RS05965	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HLV59_RS05970	ENOG4105CK2	sodium dicarboxylate symporter
HLV59_RS05975	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS05990	ENOG4105CQC	Prephenate dehydratase
HLV59_RS05995	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HLV59_RS06005	ENOG4105CIN	aminoacyl-histidine dipeptidase
HLV59_RS06025	ENOG4105E0Y	RtcB Protein
HLV59_RS06030	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HLV59_RS06035	ENOG4105CYB	regulatoR
HLV59_RS06060	ENOG4105M08	Membrane
HLV59_RS06065	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLV59_RS06075	ENOG4105VEQ	Cold shock protein
HLV59_RS06080	ENOG4105C1J	atp-dependent rna helicase
HLV59_RS06090	ENOG41069NU	Nitroreductase
HLV59_RS06125	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HLV59_RS06140	ENOG4105C5I	Dehydrogenase
HLV59_RS06145	ENOG4105ERG	peptidase m48, ste24p
HLV59_RS06150	ENOG4105KTH	gatB Yqey
HLV59_RS06205	ENOG4105VEQ	Cold shock protein
HLV59_RS06235	ENOG4105CHJ	isochorismatase hydrolase
HLV59_RS06240	ENOG4105CR8	Transcriptional regulator
HLV59_RS06245	ENOG4105D6U	Sodium Glutamate Symporter
HLV59_RS06250	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HLV59_RS06265	ENOG4105R8C	Transcriptional regulator
HLV59_RS06270	ENOG4105CEB	Aspartate aminotransferase
HLV59_RS06285	ENOG4105F1S	paraquat-inducible protein a
HLV59_RS06290	ENOG4105DY2	Paraquat-inducible protein b
HLV59_RS06300	ENOG4105VT2	5-hydroxyisourate hydrolase
HLV59_RS06315	ENOG4105GR3	Histidine kinase
HLV59_RS06340	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HLV59_RS06350	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HLV59_RS06355	ENOG4105DHQ	Histidine kinase
HLV59_RS06360	ENOG4105ETX	regulatoR
HLV59_RS06380	ENOG41081VB	Hydrolase
HLV59_RS06390	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HLV59_RS06395	ENOG4105E2B	Taurine dioxygenase
HLV59_RS06405	ENOG4105F27	Major Facilitator
HLV59_RS06420	ENOG4105HMI	Membrane
HLV59_RS06455	ENOG4105D2S	major facilitator superfamily
HLV59_RS06480	ENOG4105CK2	sodium dicarboxylate symporter
HLV59_RS06490	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HLV59_RS06495	ENOG4108UMI	ABC transporter, permease
HLV59_RS06500	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLV59_RS06505	ENOG4105D01	(LipO)protein
HLV59_RS06510	ENOG4105C12	Phosphoribosylglycinamide synthetase
HLV59_RS06520	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HLV59_RS06545	ENOG4107RNH	Outer membrane receptor FepA
HLV59_RS06550	ENOG41090R7	Ferric uptake
HLV59_RS06595	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HLV59_RS06600	ENOG4105CDU	Replicative dna helicase
HLV59_RS06625	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HLV59_RS06630	ENOG4105CCU	oxidase (Subunit III)
HLV59_RS06635	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HLV59_RS06640	ENOG4105E2S	oxidase) subunit II
HLV59_RS06665	ENOG4107BJW	polysaccharide deacetylase
HLV59_RS06670	ENOG4105CND	Glycosyl transferase, family 2
HLV59_RS06685	ENOG4105DEN	Luciferase family
HLV59_RS06700	ENOG4105CC0	LysR family Transcriptional regulator
HLV59_RS06715	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HLV59_RS06720	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HLV59_RS06725	ENOG4105GVF	(ABC) transporter
HLV59_RS06740	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS06745	ENOG4108MEJ	flavin reductase domain protein
HLV59_RS06750	ENOG4105D06	uba thif-type nad fad binding protein
HLV59_RS06760	ENOG4105KRF	dihydroneopterin aldolase
HLV59_RS06770	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HLV59_RS06775	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HLV59_RS06785	ENOG4105C08	Histidine kinase
HLV59_RS06790	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HLV59_RS06795	ENOG4105CFQ	glutamine synthetase
HLV59_RS06810	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HLV59_RS06815	ENOG4105CFU	surface antigen
HLV59_RS06835	ENOG4107QIJ	Aconitate hydratase 2
HLV59_RS06855	ENOG4105EYW	Ion transport protein
HLV59_RS06860	ENOG4105F27	Major Facilitator
HLV59_RS06870	ENOG4105DZ2	Transcriptional regulator
HLV59_RS06885	ENOG4105I08	Pseudouridine synthase
HLV59_RS06905	ENOG4105K8N	protein family UPF0079, ATPase
HLV59_RS06910	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HLV59_RS06920	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HLV59_RS06925	ENOG4108TZV	Membrane
HLV59_RS06930	ENOG4108RCM	Nitroreductase
HLV59_RS06935	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HLV59_RS06945	ENOG4105CX6	glutaminyL-tRNA synthetase
HLV59_RS06950	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HLV59_RS06955	ENOG4107FQ9	ethanolamine ammonia-lyase
HLV59_RS06960	ENOG4105CPD	ethanolamine ammonia-lyase
HLV59_RS06965	ENOG4107R55	ethanolamine transporter
HLV59_RS06975	ENOG4107RR1	TRANSCRIPTIONal
HLV59_RS06985	ENOG4105C0A	alcohol dehydrogenase
HLV59_RS06990	ENOG4107QUV	Domain protein
HLV59_RS07000	ENOG4105F4I	Transcriptional regulator
HLV59_RS07020	ENOG4105CD8	aminopeptidase N
HLV59_RS07035	ENOG4108D1K	outer membrane usher protein
HLV59_RS07060	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
HLV59_RS07070	ENOG4105GAV	receptor
HLV59_RS07075	ENOG4108ESX	Receptor
HLV59_RS07120	ENOG4105KUS	lysozyme
HLV59_RS07185	ENOG41066UD	Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium
HLV59_RS07190	ENOG4105C5H	ABC transporter
HLV59_RS07195	ENOG41081QV	Universal stress protein
HLV59_RS07215	ENOG4105DKK	Benzoate
HLV59_RS07220	ENOG4105EW9	transcriptional regulator AsnC family
HLV59_RS07225	ENOG4108NIW	Leucine export protein LeuE
HLV59_RS07235	ENOG4107RSM	transcriptional regulator
HLV59_RS07245	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS07250	ENOG4105CHR	reductase
HLV59_RS07285	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HLV59_RS07290	ENOG4105HSS	phospholipase C
HLV59_RS07300	ENOG4105C0A	alcohol dehydrogenase
HLV59_RS07340	ENOG4105CBC	glutamate synthase
HLV59_RS07355	ENOG4108D1K	outer membrane usher protein
HLV59_RS07365	ENOG4105D8G	Major Facilitator superfamily
HLV59_RS07375	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLV59_RS07380	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HLV59_RS07415	ENOG4105DUU	IucA IucC family protein
HLV59_RS07420	ENOG4105DJU	Siderophore biosynthesis protein
HLV59_RS07430	ENOG4105JSC	dimethylmenaquinone methyltransferase
HLV59_RS07460	ENOG4107QZF	nitrite reductase NADPH large subunit
HLV59_RS07465	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HLV59_RS07500	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLV59_RS07505	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HLV59_RS07515	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLV59_RS07520	ENOG4105T38	integral membrane protein
HLV59_RS07545	ENOG4105CMR	udp-glucose 4-epimerase
HLV59_RS07610	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HLV59_RS07615	ENOG4105CUX	Signal transduction histidine kinase
HLV59_RS07640	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HLV59_RS07645	ENOG4105KNE	Phosphatidate cytidylyltransferase
HLV59_RS07655	ENOG4105DZP	Membrane-associated zinc metalloprotease
HLV59_RS07660	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HLV59_RS07680	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HLV59_RS07695	ENOG4105Y3E	Modulates RecA activity (By similarity)
HLV59_RS07705	ENOG4105VEJ	Heat shock protein
HLV59_RS07710	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HLV59_RS07725	ENOG4105F7P	transcriptional regulator AsnC family
HLV59_RS07735	ENOG4105C85	amino acid
HLV59_RS07755	ENOG4105CHH	sulfate transporter
HLV59_RS07765	ENOG4105D8V	Glucose sorbosone dehydrogenase
HLV59_RS07775	ENOG4105BZU	Histidine kinase
HLV59_RS07790	ENOG4105DM4	PTS System
HLV59_RS07795	ENOG4105DE4	1-phosphofructokinase
HLV59_RS07800	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HLV59_RS07820	ENOG4108ZJF	Glcg protein
HLV59_RS07825	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HLV59_RS07830	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLV59_RS07835	ENOG4105CC0	LysR family Transcriptional regulator
HLV59_RS07845	ENOG4105M2J	Glutaredoxin
HLV59_RS07850	ENOG4105C8Y	Acetylornithine aminotransferase
HLV59_RS07855	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLV59_RS07880	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLV59_RS07890	ENOG41068P6	UPF0319 protein
HLV59_RS07905	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HLV59_RS07910	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HLV59_RS07920	ENOG4105PV3	Inner membrane protein yqiJ
HLV59_RS07940	ENOG4105HDD	phospholipase
HLV59_RS07945	ENOG4105CZN	Potassium uptake protein
HLV59_RS07955	ENOG4105C7B	Threonine dehydratase
HLV59_RS07985	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HLV59_RS07990	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLV59_RS08000	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HLV59_RS08015	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS08055	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HLV59_RS08060	ENOG4107VMU	Membrane
HLV59_RS08070	ENOG4105CNM	Receptor
HLV59_RS08075	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HLV59_RS08085	ENOG4107QP7	CoA-transferase subunit A
HLV59_RS08090	ENOG4107QNJ	CoA-transferase subunit B
HLV59_RS08095	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS08100	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HLV59_RS08105	ENOG4105F2Z	3-oxoadipate enol-lactonase
HLV59_RS08110	ENOG4105D2S	major facilitator superfamily
HLV59_RS08115	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HLV59_RS08120	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
HLV59_RS08125	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
HLV59_RS08130	ENOG4105FF2	Type I DHQase
HLV59_RS08135	ENOG4106JPM	3-dehydroshikimate dehydratase
HLV59_RS08140	ENOG4105TW1	Carbohydrate-selective porin OprB
HLV59_RS08145	ENOG4105DZG	Dehydrogenase
HLV59_RS08155	ENOG4105MD1	YeeE YedE family protein
HLV59_RS08170	ENOG4107HP6	Transcriptional regulator
HLV59_RS08175	ENOG4108PTX	LysR family Transcriptional regulator
HLV59_RS08180	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS08205	ENOG4105DNH	Major Facilitator
HLV59_RS08215	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HLV59_RS08235	ENOG4105FUY	alpha subunit
HLV59_RS08245	ENOG4105CHR	reductase
HLV59_RS08265	ENOG4105F11	amine oxidase
HLV59_RS08280	ENOG4105C26	Dehydrogenase
HLV59_RS08285	ENOG4105F2Z	3-oxoadipate enol-lactonase
HLV59_RS08290	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS08295	ENOG4107QNJ	CoA-transferase subunit B
HLV59_RS08300	ENOG4107QP7	CoA-transferase subunit A
HLV59_RS08310	ENOG4105NN7	muconolactone delta-isomerase
HLV59_RS08315	ENOG4105DTQ	mandelate racemase muconate lactonizing
HLV59_RS08320	ENOG4108KB2	LysR family Transcriptional regulator
HLV59_RS08330	ENOG4107EJG	GntR family transcriptional regulator
HLV59_RS08350	ENOG4105CZJ	Aldehyde dehydrogenase
HLV59_RS08355	ENOG4108JGH	Tetr family transcriptional regulator
HLV59_RS08360	ENOG4105CJP	fad dependent oxidoreductase
HLV59_RS08385	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HLV59_RS08390	ENOG4105BZS	acriflavin resistance protein
HLV59_RS08395	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HLV59_RS08400	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLV59_RS08405	ENOG4105EB3	Histidine kinase
HLV59_RS08435	ENOG4105CT3	Monooxygenase
HLV59_RS08440	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
HLV59_RS08475	ENOG4105C29	acyl-CoA thioesterase
HLV59_RS08480	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS08485	ENOG4105G2Y	Transcriptional regulator
HLV59_RS08490	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS08505	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HLV59_RS08510	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HLV59_RS08515	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HLV59_RS08525	ENOG4105CSU	acyl-Coa dehydrogenase
HLV59_RS08530	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS08540	ENOG4107TE1	transport protein
HLV59_RS08545	ENOG4105KME	endoribonuclease L-psp
HLV59_RS08555	ENOG4105CSU	acyl-Coa dehydrogenase
HLV59_RS08575	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS08580	ENOG4105CHR	reductase
HLV59_RS08585	ENOG4108JU7	Transcriptional regulator
HLV59_RS08605	ENOG4105CHR	reductase
HLV59_RS08610	ENOG4107HP6	Transcriptional regulator
HLV59_RS08615	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HLV59_RS08625	ENOG4105D2S	major facilitator superfamily
HLV59_RS08630	ENOG4105TW1	Carbohydrate-selective porin OprB
HLV59_RS08650	ENOG4105D2S	major facilitator superfamily
HLV59_RS08655	ENOG4105E2X	shikimate dehydrogenase
HLV59_RS08665	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HLV59_RS08670	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HLV59_RS08680	ENOG4108SY4	MarR family Transcriptional regulator
HLV59_RS08685	ENOG4105E39	Enoyl-CoA hydratase
HLV59_RS08690	ENOG4105D2S	major facilitator superfamily
HLV59_RS08695	ENOG4105BZJ	Electron transfer flavoprotein
HLV59_RS08700	ENOG4105C10	Electron transfer flavoprotein
HLV59_RS08710	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HLV59_RS08720	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS08725	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS08735	ENOG4108IPT	Naphthoate synthase
HLV59_RS08745	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS08755	ENOG4105IKQ	hydratase
HLV59_RS08760	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HLV59_RS08765	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HLV59_RS08770	ENOG4105EPF	Outer membrane porin
HLV59_RS08780	ENOG4108W5M	transcriptional regulator
HLV59_RS08785	ENOG4105FUY	alpha subunit
HLV59_RS08790	ENOG4108SBK	dioxygenase, subunit beta
HLV59_RS08800	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
HLV59_RS08805	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
HLV59_RS08810	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HLV59_RS08815	ENOG4108SC4	)-transporter
HLV59_RS08820	ENOG4105CZM	Major Facilitator
HLV59_RS08825	ENOG4108W5M	transcriptional regulator
HLV59_RS08845	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS08890	ENOG4107Z3H	Transcriptional regulator, TetR family
HLV59_RS08900	ENOG4105E1F	short-chain dehydrogenase reductase
HLV59_RS08910	ENOG4105KVH	Transcriptional regulator
HLV59_RS08915	ENOG4105ECR	NmrA family
HLV59_RS08920	ENOG4108ZX5	transcriptional regulator
HLV59_RS08925	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HLV59_RS08930	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
HLV59_RS08940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS09030	ENOG4105EVZ	LysR family transcriptional regulator
HLV59_RS09035	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HLV59_RS09040	ENOG4105C26	Dehydrogenase
HLV59_RS09060	ENOG4105MSY	salicylate hydroxylase
HLV59_RS09080	ENOG4105CW7	secretion protein, HlyD family
HLV59_RS09095	ENOG4105CZJ	Aldehyde dehydrogenase
HLV59_RS09110	ENOG4105DDW	LysR family Transcriptional regulator
HLV59_RS09115	ENOG4105EXW	epimerase dehydratase
HLV59_RS09125	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HLV59_RS09130	ENOG4105CF7	AraC family transcriptional regulator
HLV59_RS09135	ENOG4105DQ4	alcohol dehydrogenase
HLV59_RS09165	ENOG4105EHG	Permease protein
HLV59_RS09170	ENOG4105E0A	ABC, transporter
HLV59_RS09185	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HLV59_RS09290	ENOG4105ENX	hydrolase
HLV59_RS09295	ENOG4105EQ2	LysR family Transcriptional regulator
HLV59_RS09310	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLV59_RS09335	ENOG4105X0I	Fimbrial
HLV59_RS09390	ENOG4107RZC	phospholipase d
HLV59_RS09410	ENOG4108IGT	Dipeptidase
HLV59_RS09415	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HLV59_RS09425	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
HLV59_RS09430	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
HLV59_RS09445	ENOG4107T31	5'-nucleotidase
HLV59_RS09455	ENOG4105WQI	isochorismatase
HLV59_RS09460	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HLV59_RS09475	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HLV59_RS09480	ENOG4105E0C	molybdate abc transporter
HLV59_RS09485	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HLV59_RS09490	ENOG4105F4R	Transcriptional regulator mode
HLV59_RS09495	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
HLV59_RS09500	ENOG4108YS2	small subunit
HLV59_RS09505	ENOG4105F57	Anthranilate dioxygenase reductase
HLV59_RS09530	ENOG4105CHR	reductase
HLV59_RS09545	ENOG4105D2S	major facilitator superfamily
HLV59_RS09550	ENOG4105CF7	AraC family transcriptional regulator
HLV59_RS09555	ENOG4105DTD	Dehydrogenase
HLV59_RS09560	ENOG4105CY2	Citrate transporter
HLV59_RS09580	ENOG4108M0I	Transcriptional regulator
HLV59_RS09595	ENOG4105CRW	Short chain fatty acid transporter
HLV59_RS09600	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS09610	ENOG4107YNJ	LysR family Transcriptional regulator
HLV59_RS09625	ENOG4108IJ0	Aspartate ammonia-lyase
HLV59_RS09635	ENOG4105CSH	Transporter
HLV59_RS09660	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HLV59_RS09690	ENOG4105KVH	Transcriptional regulator
HLV59_RS09695	ENOG4105UEI	Transcriptional Regulator AraC Family
HLV59_RS09710	ENOG4108VCT	Sulfite exporter TauE/SafE
HLV59_RS09720	ENOG4107QPB	Beta-lactamase domain protein
HLV59_RS09730	ENOG4105FFC	UPF0187 protein
HLV59_RS09740	ENOG4105CHR	reductase
HLV59_RS09755	ENOG4105CPP	Dehydrogenase, E1 component
HLV59_RS09760	ENOG4107R0V	Pyruvate dehydrogenase
HLV59_RS09765	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HLV59_RS09780	ENOG4105BZU	Histidine kinase
HLV59_RS09795	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HLV59_RS09800	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HLV59_RS09845	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HLV59_RS09855	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HLV59_RS09870	ENOG4105C28	cystathionine
HLV59_RS09885	ENOG4105K59	histidine triad (HIT) protein
HLV59_RS09910	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HLV59_RS09915	ENOG4105CNM	Receptor
HLV59_RS09935	ENOG4107TSN	permease
HLV59_RS09940	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HLV59_RS09960	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HLV59_RS09965	ENOG4108YZT	Adenosylcobinamide kinase
HLV59_RS09975	ENOG4107VXZ	Hydrolase
HLV59_RS09980	ENOG4108Z66	YbaK ebsC protein
HLV59_RS09995	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS10000	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS10005	ENOG4105EEF	Alkane 1-monooxygenase
HLV59_RS10010	ENOG4105E7U	AraC family transcriptional regulator
HLV59_RS10015	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HLV59_RS10020	ENOG4105K70	DNA-binding protein
HLV59_RS10035	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HLV59_RS10045	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HLV59_RS10050	ENOG4108Z4V	iron-sulfur cluster assembly
HLV59_RS10065	ENOG4108ZIT	Ferredoxin, 2FE-2S
HLV59_RS10070	ENOG4105F8J	Adenylate Guanylate cyclase
HLV59_RS10080	ENOG4108JA2	transcriptioN-repair coupling factor
HLV59_RS10100	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HLV59_RS10105	ENOG4105K4T	epimerase
HLV59_RS10120	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HLV59_RS10150	ENOG4105DGW	oligopeptidase A
HLV59_RS10155	ENOG4107QSI	ABC, transporter
HLV59_RS10190	ENOG4105SG9	biopolymer transport protein, ExbD
HLV59_RS10195	ENOG4107QP3	malate synthase g
HLV59_RS10200	ENOG4105D6Z	AFG1 family ATPase
HLV59_RS10210	ENOG4107RN6	Monooxygenase
HLV59_RS10215	ENOG4105DWU	Membrane
HLV59_RS10230	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HLV59_RS10235	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HLV59_RS10250	ENOG4108Z6B	deaminase
HLV59_RS10270	ENOG4108RTD	type II secretion system protein K
HLV59_RS10295	ENOG4105F8V	Hydrolase, tatD family
HLV59_RS10305	ENOG4107QRG	dna polymerase iii
HLV59_RS10315	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HLV59_RS10320	ENOG4105BZ1	(ABC) transporter
HLV59_RS10335	ENOG4105FA0	parb-like partition protein
HLV59_RS10340	ENOG4107QJE	Chromosome Partitioning Protein
HLV59_RS10350	ENOG4108S0S	Nucleotidyl transferase
HLV59_RS10355	ENOG4105EHM	Aminoglycoside phosphotransferase
HLV59_RS10360	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HLV59_RS10365	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HLV59_RS10370	ENOG4105D2N	Aldolase
HLV59_RS10390	ENOG4108UHJ	MAF-like protein
HLV59_RS10395	ENOG4105EZE	Cupin 4 family protein
HLV59_RS10405	ENOG41080HT	Transcriptional regulator, arsr family
HLV59_RS10415	ENOG4105XPP	Protein of unknown function (DUF1275)
HLV59_RS10420	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HLV59_RS10435	ENOG4108ZX5	transcriptional regulator
HLV59_RS10445	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HLV59_RS10450	ENOG4105CK7	Sodium proline symporter
HLV59_RS10455	ENOG4105EW9	transcriptional regulator AsnC family
HLV59_RS10460	ENOG4105C26	Dehydrogenase
HLV59_RS10465	ENOG4105YGK	Pfam:UPF0157
HLV59_RS10480	ENOG4108T58	Mg2 transport protein CorA
HLV59_RS10490	ENOG4108YYC	ycei family
HLV59_RS10500	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HLV59_RS10525	ENOG4108HWY	Beta-lactamase
HLV59_RS10530	ENOG4108Z7F	N-acetyltransferase
HLV59_RS10545	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HLV59_RS10550	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HLV59_RS10570	ENOG4105X0I	Fimbrial
HLV59_RS10575	ENOG4105GQR	Chaperone
HLV59_RS10605	ENOG4108R4R	Iron-regulated virulence regulatory protein
HLV59_RS10610	ENOG4108IPJ	Membrane
HLV59_RS10620	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HLV59_RS10630	ENOG4105HEI	LysR family (Transcriptional regulator
HLV59_RS10645	ENOG41067SE	Tetr family transcriptional regulator
HLV59_RS10660	ENOG4105EW9	transcriptional regulator AsnC family
HLV59_RS10670	ENOG4105CDA	abc transporter atp-binding protein
HLV59_RS10675	ENOG4105DRP	amino acid AbC transporter
HLV59_RS10680	ENOG4105EAD	ABC transporter
HLV59_RS10695	ENOG4107T8P	acyl-Coa dehydrogenase
HLV59_RS10710	ENOG4105D01	(LipO)protein
HLV59_RS10715	ENOG4105D01	(LipO)protein
HLV59_RS10720	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLV59_RS10725	ENOG4108UMI	ABC transporter, permease
HLV59_RS10730	ENOG4105C3G	gtp-binding protein
HLV59_RS10750	ENOG4108UMN	azlc family
HLV59_RS10755	ENOG4105ZED	uncharacterized protein ygaH
HLV59_RS10785	ENOG4106AXJ	AraC family transcriptional regulator
HLV59_RS10790	ENOG4108V06	Glutathione peroxidase
HLV59_RS10800	ENOG4105CHM	Aminotransferase
HLV59_RS10805	ENOG4105CK2	sodium dicarboxylate symporter
HLV59_RS10815	ENOG4105C0B	DNA polymerase III (alpha subunit)
HLV59_RS10840	ENOG4108JU3	Alkyl hydroperoxide reductase
HLV59_RS10855	ENOG4108KB2	LysR family Transcriptional regulator
HLV59_RS10860	ENOG4105CAU	Arsenical resistance protein, ArsH
HLV59_RS10865	ENOG4105D6J	arsenicaL-resistance protein
HLV59_RS10875	ENOG41082YX	Transcriptional regulator, arsr family
HLV59_RS10890	ENOG4105CPN	adenine deaminase
HLV59_RS10900	ENOG4105CBN	LysR family transcriptional regulator
HLV59_RS10910	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HLV59_RS10925	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HLV59_RS10930	ENOG4108IY8	ABC, transporter
HLV59_RS10935	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HLV59_RS10945	ENOG4105C54	Major Facilitator superfamily
HLV59_RS10965	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HLV59_RS10970	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HLV59_RS10980	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLV59_RS10985	ENOG4108K70	Transcriptional regulator
HLV59_RS11000	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HLV59_RS11005	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
HLV59_RS11020	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HLV59_RS11025	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HLV59_RS11035	ENOG4105ETT	transcriptional Regulator, LysR family
HLV59_RS11050	ENOG4105DXI	Major Facilitator superfamily
HLV59_RS11070	ENOG41067MG	lrgb family
HLV59_RS11075	ENOG4105VAW	lrga family
HLV59_RS11080	ENOG4105CMU	LysR family (Transcriptional regulator
HLV59_RS11085	ENOG4108SHQ	Glutathione S-transferase
HLV59_RS11090	ENOG4105CYM	Glutathione S-transferase
HLV59_RS11095	ENOG4105CBN	LysR family transcriptional regulator
HLV59_RS11100	ENOG4105CHR	reductase
HLV59_RS11110	ENOG4105D7W	serine acetyltransferase
HLV59_RS11115	ENOG4105ESN	nucleotide-binding protein
HLV59_RS11120	ENOG4105C9B	Cysteine desulfurase
HLV59_RS11125	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HLV59_RS11130	ENOG4105EXG	Transcriptional regulator
HLV59_RS11135	ENOG4105CT1	(ABC) transporter
HLV59_RS11140	ENOG4107RP9	extracellular solute-binding protein, family 3
HLV59_RS11150	ENOG4108HW4	amino acid AbC transporter
HLV59_RS11155	ENOG4105EAD	ABC transporter
HLV59_RS11170	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLV59_RS11175	ENOG4105BZU	Histidine kinase
HLV59_RS11185	ENOG4105EW9	transcriptional regulator AsnC family
HLV59_RS11195	ENOG4105KT5	UmuD protein
HLV59_RS11215	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLV59_RS11260	ENOG4105HEI	LysR family (Transcriptional regulator
HLV59_RS11270	ENOG4105D2S	major facilitator superfamily
HLV59_RS11280	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HLV59_RS11285	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS11290	ENOG4105R8C	Transcriptional regulator
HLV59_RS11295	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS11300	ENOG4107QX3	carboxylase
HLV59_RS11305	ENOG4105E39	Enoyl-CoA hydratase
HLV59_RS11320	ENOG4105CC0	LysR family Transcriptional regulator
HLV59_RS11335	ENOG4105CSU	acyl-Coa dehydrogenase
HLV59_RS11355	ENOG4107QNJ	CoA-transferase subunit B
HLV59_RS11360	ENOG4107QP7	CoA-transferase subunit A
HLV59_RS11365	ENOG4107RGD	Major Facilitator superfamily
HLV59_RS11370	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS11375	ENOG4105E39	Enoyl-CoA hydratase
HLV59_RS11380	ENOG4105CHR	reductase
HLV59_RS11385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HLV59_RS11390	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS11400	ENOG4105EQ0	Major Facilitator superfamily
HLV59_RS11405	ENOG4105EA8	2-Nitropropane dioxygenase
HLV59_RS11410	ENOG4108UKI	Enoyl-CoA hydratase
HLV59_RS11425	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS11430	ENOG4107RGD	Major Facilitator superfamily
HLV59_RS11435	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HLV59_RS11440	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HLV59_RS11450	ENOG4107RCV	ABC transporter, permease
HLV59_RS11455	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLV59_RS11460	ENOG4105C4Y	ABC transporter
HLV59_RS11475	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
HLV59_RS11480	ENOG4107HP6	Transcriptional regulator
HLV59_RS11485	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HLV59_RS11490	ENOG4105C26	Dehydrogenase
HLV59_RS11500	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HLV59_RS11510	ENOG4105C26	Dehydrogenase
HLV59_RS11515	ENOG4108M8W	Monooxygenase
HLV59_RS11520	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HLV59_RS11525	ENOG4108MXF	Alpha Beta Hydrolase
HLV59_RS11565	ENOG4105VEQ	Cold shock protein
HLV59_RS11595	ENOG4108JGH	Tetr family transcriptional regulator
HLV59_RS11600	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HLV59_RS11615	ENOG4105EMU	Dehydrogenase
HLV59_RS11620	ENOG4105BZS	acriflavin resistance protein
HLV59_RS11640	ENOG4108W6C	Dehydrogenase
HLV59_RS11655	ENOG4105UQX	Mate efflux family protein
HLV59_RS11660	ENOG4108JGH	Tetr family transcriptional regulator
HLV59_RS11680	ENOG4108TGR	phosphatase
HLV59_RS11695	ENOG4107YAU	phenylacetic acid degradation protein
HLV59_RS11700	ENOG4108Z0R	Transferase
HLV59_RS11705	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
HLV59_RS11710	ENOG4105DZS	Phenylacetate-CoA ligase
HLV59_RS11715	ENOG4105CHU	acetyl-coa acetyltransferase
HLV59_RS11720	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HLV59_RS11725	ENOG4108UKI	Enoyl-CoA hydratase
HLV59_RS11730	ENOG4105E39	Enoyl-CoA hydratase
HLV59_RS11735	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HLV59_RS11740	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HLV59_RS11745	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HLV59_RS11750	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HLV59_RS11755	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HLV59_RS11760	ENOG4105DXM	phenylacetic acid degradation protein
HLV59_RS11765	ENOG4105EJQ	L-serine dehydratase
HLV59_RS11770	ENOG4108RNG	Permease of the drug metabolite transporter
HLV59_RS11780	ENOG4108Z4X	TRANSCRIPTIONal
HLV59_RS11790	ENOG4105WPN	DNA integration recombination invertion protein
HLV59_RS11795	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLV59_RS11810	ENOG4105DJ2	Major Facilitator Superfamily
HLV59_RS11815	ENOG4107Y2X	deaminase
HLV59_RS11825	ENOG4105EMY	transcriptional regulator
HLV59_RS11855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLV59_RS11965	ENOG4105CNA	YD repeat protein
HLV59_RS12000	ENOG4105MRR	Transcriptional regulator (By similarity)
HLV59_RS12010	ENOG4105KVH	Transcriptional regulator
HLV59_RS12015	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
HLV59_RS12020	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLV59_RS12035	ENOG4105E2A	Dehydrogenase
HLV59_RS12040	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HLV59_RS12100	ENOG4107R4J	Chloride channel
HLV59_RS12105	ENOG4108JIK	carboxylase
HLV59_RS12125	ENOG4105C5A	transporter
HLV59_RS12140	ENOG4108WQI	RNA Polymerase
HLV59_RS12150	ENOG4105E18	UPF0276 protein
HLV59_RS12185	ENOG4105D7N	magnesium and cobalt transport protein CorA
HLV59_RS12220	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HLV59_RS12225	ENOG4108IND	Tetr family transcriptional regulator
HLV59_RS12250	ENOG4105BZU	Histidine kinase
HLV59_RS12260	ENOG4108S3W	Anti-feci sigma factor, fecr
HLV59_RS12285	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HLV59_RS12310	ENOG4105D2S	major facilitator superfamily
HLV59_RS12315	ENOG4105CPW	cytochrome b561
HLV59_RS12320	ENOG4107VGR	Catalase
HLV59_RS12325	ENOG4105KVH	Transcriptional regulator
HLV59_RS12355	ENOG4108Z4U	Ferredoxin
HLV59_RS12375	ENOG4105EQK	-acetyltransferase
HLV59_RS12385	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HLV59_RS12385	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HLV59_RS12395	ENOG4105DFG	type I secretion outer membrane protein
HLV59_RS12400	ENOG4108IUZ	ABC transporter
HLV59_RS12405	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HLV59_RS12415	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HLV59_RS12420	ENOG4105C2X	Arabinose 5-phosphate isomerase
HLV59_RS12465	ENOG4105CUY	Mechanosensitive ion channel
HLV59_RS12510	ENOG4105R8C	Transcriptional regulator
HLV59_RS12540	ENOG4105F2W	methyltransferase
HLV59_RS12545	ENOG4105EW9	transcriptional regulator AsnC family
HLV59_RS12555	ENOG4105II7	pyrroline-5-carboxylate reductase
HLV59_RS12565	ENOG4105VEQ	Cold shock protein
HLV59_RS12570	ENOG4105D1S	lipid A biosynthesis
HLV59_RS12575	ENOG410829K	Lysine exporter protein (Lyse ygga)
HLV59_RS12610	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HLV59_RS12670	ENOG4105EUV	Phenol 2-monooxygenase
HLV59_RS12690	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HLV59_RS12700	ENOG4108KB2	LysR family Transcriptional regulator
HLV59_RS12710	ENOG4105FUY	alpha subunit
HLV59_RS12715	ENOG4108UKV	benzoate 1,2-dioxygenase
HLV59_RS12720	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HLV59_RS12725	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
HLV59_RS12730	ENOG4105DKK	Benzoate
HLV59_RS12735	ENOG4105D2S	major facilitator superfamily
HLV59_RS12750	ENOG4105CQ7	ATP-dependent helicase
HLV59_RS12755	ENOG4105D3R	alkyl hydroperoxide reductase
HLV59_RS12775	ENOG4108JU3	Alkyl hydroperoxide reductase
HLV59_RS12785	ENOG4108K3A	Glutathione S-transferase
HLV59_RS12795	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HLV59_RS12810	ENOG4108TGY	Glutathione S-transferase
HLV59_RS12820	ENOG4108ZG0	Ompa motb domain protein
HLV59_RS12825	ENOG4105CD3	dihydroorotase
HLV59_RS12850	ENOG4105CEV	competence damage-inducible protein
HLV59_RS12855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLV59_RS12870	ENOG4108UKZ	OsmC family
HLV59_RS12880	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HLV59_RS12885	ENOG4105CPC	Aldo Keto reductase
HLV59_RS12900	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HLV59_RS12915	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HLV59_RS12925	ENOG4105CFH	Aspartokinase
HLV59_RS12935	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HLV59_RS12945	ENOG4105CPW	cytochrome b561
HLV59_RS12950	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HLV59_RS12955	ENOG4105C7N	Xanthine uracil vitamin C permease
HLV59_RS12985	ENOG4105F95	Monooxygenase
HLV59_RS12990	ENOG4105JQZ	Methyltransferase
HLV59_RS12995	ENOG4105EJC	lysr family transcriptional regulator
HLV59_RS13010	ENOG4107GFK	fumarate
HLV59_RS13020	ENOG4107RN6	Monooxygenase
HLV59_RS13040	ENOG4105DDY	UPF0142 protein ycaO
HLV59_RS13045	ENOG4105EPF	Outer membrane porin
HLV59_RS13050	ENOG4105D2S	major facilitator superfamily
HLV59_RS13055	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HLV59_RS13060	ENOG4105E6M	Sulphatase-modifying factor protein
HLV59_RS13075	ENOG4105E3J	oxidoreductase
HLV59_RS13090	ENOG4108SC4	)-transporter
HLV59_RS13095	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HLV59_RS13110	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS13115	ENOG4105EPF	Outer membrane porin
HLV59_RS13120	ENOG4105NI3	Protein of unknown function (DUF3237)
HLV59_RS13135	ENOG4105JXH	GntR family transcriptional regulator
HLV59_RS13140	ENOG4105CZJ	Aldehyde dehydrogenase
HLV59_RS13150	ENOG4105EQX	glucarate dehydratase
HLV59_RS13155	ENOG4105DJB	Major Facilitator Superfamily
HLV59_RS13160	ENOG4105CTX	dehydratase
HLV59_RS13165	ENOG4105DJP	Membrane
HLV59_RS13170	ENOG4108ZX5	transcriptional regulator
HLV59_RS13175	ENOG4107RGH	Aldehyde dehydrogenase
HLV59_RS13195	ENOG4105C85	amino acid
HLV59_RS13215	ENOG4105C26	Dehydrogenase
HLV59_RS13235	ENOG4105CUB	amino acid
HLV59_RS13245	ENOG4105C85	amino acid
HLV59_RS13255	ENOG4107Y60	(LipO)protein
HLV59_RS13265	ENOG4106B0W	Curli production assembly transport component CsgG
HLV59_RS13280	ENOG4105D01	(LipO)protein
HLV59_RS13290	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLV59_RS13310	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HLV59_RS13330	ENOG4108JQ5	ABC transporter
HLV59_RS13335	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HLV59_RS13340	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HLV59_RS13345	ENOG4105E43	Extracellular solute-binding protein, family 5
HLV59_RS13350	ENOG4105E9H	Lytic Murein transglycosylase
HLV59_RS13355	ENOG4107RZZ	dna polymerase iii epsilon subunit
HLV59_RS13365	ENOG4105E09	nadh pyrophosphatase
HLV59_RS13375	ENOG4105W4M	Transport-associated protein
HLV59_RS13385	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HLV59_RS13395	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HLV59_RS13400	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HLV59_RS13420	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HLV59_RS13425	ENOG4105D0A	hydroxylase
HLV59_RS13430	ENOG4107RAQ	aminopeptidase
HLV59_RS13470	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HLV59_RS13485	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HLV59_RS13495	ENOG4105D82	Glutamate dehydrogenase
HLV59_RS13500	ENOG4108R3D	Electron transport complex
HLV59_RS13505	ENOG4105CSM	endonuclease III
HLV59_RS13530	ENOG4105CJN	penicillin-binding protein
HLV59_RS13535	ENOG4106H78	methyltransferase
HLV59_RS13550	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HLV59_RS13560	ENOG4105CQM	Urea amidohydrolase subunit alpha
HLV59_RS13585	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HLV59_RS13590	ENOG4107RET	Isocitrate lyase
HLV59_RS13600	ENOG4105C37	(CBS) domain
HLV59_RS13605	ENOG4105D4T	Citrate transporter
HLV59_RS13625	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HLV59_RS13640	ENOG4108MRJ	
HLV59_RS13660	ENOG4105VCQ	rubredoxin
HLV59_RS13665	ENOG4107QZF	nitrite reductase NADPH large subunit
HLV59_RS13670	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HLV59_RS13675	ENOG4105C5Q	Transcriptional regulator
HLV59_RS13700	ENOG4107U91	Rhomboid family
HLV59_RS13705	ENOG4105CV6	ABC transporter, permease
HLV59_RS13710	ENOG4108I0Y	(ABC) transporter
HLV59_RS13715	ENOG4108UJV	acyl-CoA thioesterase i
HLV59_RS13735	ENOG4105D05	Receptor
HLV59_RS13750	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HLV59_RS13755	ENOG4105E6M	Sulphatase-modifying factor protein
HLV59_RS13775	ENOG4105CJ3	phosphate transporter
HLV59_RS13780	ENOG4105C3R	Methionine synthase
HLV59_RS13795	ENOG4105CSP	Major Facilitator Superfamily
HLV59_RS13805	ENOG4108PZW	LysR family Transcriptional regulator
HLV59_RS13810	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HLV59_RS13820	ENOG4105EU0	Major facilitator Superfamily
HLV59_RS13825	ENOG4108R6W	Transcriptional regulator, ARAC family
HLV59_RS13830	ENOG4105CSV	Glutaminase
HLV59_RS13835	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HLV59_RS13840	ENOG4105CSH	Transporter
HLV59_RS13850	ENOG4105C7K	acetolactate synthase
HLV59_RS13865	ENOG4105CHR	reductase
HLV59_RS13870	ENOG4108MXF	Alpha Beta Hydrolase
HLV59_RS13880	ENOG4105DJB	Major Facilitator Superfamily
HLV59_RS13915	ENOG41069M3	Transcriptional regulator
HLV59_RS13940	ENOG4105CND	Glycosyl transferase, family 2
HLV59_RS13945	ENOG4107BJW	polysaccharide deacetylase
HLV59_RS13955	ENOG4108VWS	Yaeq family
HLV59_RS13965	ENOG4105CKI	cobalamin synthesis protein
HLV59_RS13975	ENOG4108S4H	thioesterase Superfamily protein
HLV59_RS13985	ENOG4105C94	Transporter
HLV59_RS13990	ENOG4105C94	Transporter
HLV59_RS13995	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HLV59_RS14020	ENOG4107QK5	Homocysteine s-methyltransferase
HLV59_RS14025	ENOG4105D5Q	Arginine ornithine antiporter
HLV59_RS14050	ENOG4108YNN	Heme oxygenase
HLV59_RS14080	ENOG4108SF5	RNA Polymerase
HLV59_RS14090	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLV59_RS14095	ENOG4105C54	Major Facilitator superfamily
HLV59_RS14125	ENOG4105DZR	Type I site-specific deoxyribonuclease
HLV59_RS14135	ENOG4105CVR	type I restriction-modification system
HLV59_RS14145	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HLV59_RS14150	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLV59_RS14155	ENOG4105CW7	secretion protein, HlyD family
HLV59_RS14160	ENOG4108VUY	thioesterase Superfamily protein
HLV59_RS14165	ENOG4105D52	delta-aminolevulinic acid dehydratase
HLV59_RS14170	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HLV59_RS14175	ENOG4105ECP	epimerase
HLV59_RS14195	ENOG4107RH8	nuclease SbcCD subunit D
HLV59_RS14200	ENOG4105EYH	Exonuclease
HLV59_RS14205	ENOG4105DFA	alanine racemase domain protein
HLV59_RS14210	ENOG4105CZX	twitching motility protein
HLV59_RS14215	ENOG4105CZX	twitching motility protein
HLV59_RS14220	ENOG41090R7	Ferric uptake
HLV59_RS14230	ENOG4105VDB	UPF0125 protein
HLV59_RS14245	ENOG4105E7A	Glutamine amidotransferase
HLV59_RS14260	ENOG4107QKV	phosphomannomutase
HLV59_RS14270	ENOG4105C4R	Atp-dependent dna helicase
HLV59_RS14275	ENOG4108ZG0	Ompa motb domain protein
HLV59_RS14280	ENOG4106HNH	Acyl-transferase
HLV59_RS14295	ENOG4107QMS	site-determining protein
HLV59_RS14310	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HLV59_RS14315	ENOG4105CNU	cell division protein FtsK
HLV59_RS14320	ENOG4105C3M	thioredoxin reductase
HLV59_RS14325	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HLV59_RS14335	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HLV59_RS14350	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HLV59_RS14355	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HLV59_RS14365	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HLV59_RS14380	ENOG4108YXA	Membrane
HLV59_RS14390	ENOG4105C4K	Nad synthetase
HLV59_RS14405	ENOG4105E3J	oxidoreductase
HLV59_RS14410	ENOG4105C26	Dehydrogenase
HLV59_RS14415	ENOG4105DVW	rieske (2Fe-2S)
HLV59_RS14425	ENOG4105C94	Transporter
HLV59_RS14430	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLV59_RS14435	ENOG4105EJC	lysr family transcriptional regulator
HLV59_RS14455	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HLV59_RS14475	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HLV59_RS14480	ENOG4105C34	Pseudouridine synthase
HLV59_RS14485	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HLV59_RS14490	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HLV59_RS14505	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HLV59_RS14535	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HLV59_RS14565	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HLV59_RS14570	ENOG4107XGZ	Hydrolase
HLV59_RS14575	ENOG4105DWF	phosphomethylpyrimidine kinase
HLV59_RS14580	ENOG4109066	lysm domain bon superfamily protein
HLV59_RS14590	ENOG4105CHR	reductase
HLV59_RS14595	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HLV59_RS14605	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HLV59_RS14610	ENOG4108BPE	-transporting atpase
HLV59_RS14615	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HLV59_RS14620	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HLV59_RS14625	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HLV59_RS14630	ENOG4105FE9	pseudouridine synthase
HLV59_RS14640	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HLV59_RS14645	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HLV59_RS14655	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HLV59_RS14660	ENOG4108K4C	ec 3.1.3.12
HLV59_RS14665	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HLV59_RS14670	ENOG4106UW1	Major Facilitator superfamily
HLV59_RS14690	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HLV59_RS14700	ENOG4105HF0	Membrane
HLV59_RS14715	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLV59_RS14725	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HLV59_RS14770	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HLV59_RS14775	ENOG4105D1F	ATP-binding protein
HLV59_RS14785	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HLV59_RS14820	ENOG4105K6H	D-cysteine desulfhydrase
HLV59_RS14825	ENOG4105CBX	hi0933 family
HLV59_RS14850	ENOG4105DP0	ferredoxin-NADP reductase
HLV59_RS14855	ENOG4105DUM	transcriptional regulator, lysR family
HLV59_RS14875	ENOG4105C8S	subunit m
HLV59_RS14880	ENOG4105D65	subunit l
HLV59_RS14890	ENOG4107UFS	subunit j
HLV59_RS14905	ENOG4108IEH	NADH dehydrogenase subunit g
HLV59_RS14910	ENOG4107QIZ	NADH dehydrogenase
HLV59_RS14915	ENOG4105GKE	subunit e
HLV59_RS14935	ENOG4105BZU	Histidine kinase
HLV59_RS14945	ENOG4105E0F	Histidine kinase
HLV59_RS14950	ENOG4107EXC	regulatoR
HLV59_RS14955	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLV59_RS14965	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLV59_RS15005	ENOG4105EQK	-acetyltransferase
HLV59_RS15010	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
HLV59_RS15045	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HLV59_RS15060	ENOG4105ETT	transcriptional Regulator, LysR family
HLV59_RS15080	ENOG4105CH2	amidohydrolase
HLV59_RS15115	ENOG4106P55	Transcriptional regulator
HLV59_RS15130	ENOG4106P55	Transcriptional regulator
HLV59_RS15135	ENOG4107EFR	Flavocytochrome c
HLV59_RS15160	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HLV59_RS15165	ENOG4107RGD	Major Facilitator superfamily
HLV59_RS15170	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS15175	ENOG4105ETT	transcriptional Regulator, LysR family
HLV59_RS15210	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HLV59_RS15215	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HLV59_RS15220	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HLV59_RS15240	ENOG4105E3B	Multicopper oxidase
HLV59_RS15250	ENOG4108HCJ	Hydrolase
HLV59_RS15255	ENOG4105DJV	ribulose-phosphate 3-epimerase
HLV59_RS15265	ENOG4105C4W	S-formylglutathione hydrolase
HLV59_RS15280	ENOG41072GX	Peptidase M22 Glycoprotease
HLV59_RS15285	ENOG4108Z0R	Transferase
HLV59_RS15340	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HLV59_RS15345	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HLV59_RS15350	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HLV59_RS15420	ENOG4105K56	Transcriptional regulator
HLV59_RS15425	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HLV59_RS15430	ENOG4107QHF	type ii secretion system protein e
HLV59_RS15450	ENOG4105C2M	dna polymerase I
HLV59_RS15455	ENOG4108VIA	integral membrane protein
HLV59_RS15460	ENOG4105II7	pyrroline-5-carboxylate reductase
HLV59_RS15465	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HLV59_RS15475	ENOG4105C9X	ppx gppa phosphatase
HLV59_RS15485	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HLV59_RS15505	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HLV59_RS15530	ENOG41082NX	50s ribosomal protein l35
HLV59_RS15545	ENOG4105W39	Membrane
HLV59_RS15550	ENOG4105CYM	Glutathione S-transferase
HLV59_RS15565	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS15570	ENOG4105N42	UPF0307 protein
HLV59_RS15575	ENOG41080Z8	PHOSPHOCARRIER protein
HLV59_RS15595	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLV59_RS15600	ENOG4105DJ0	Poly(A) Polymerase
HLV59_RS15605	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HLV59_RS15610	ENOG4105DXN	mazG family
HLV59_RS15620	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HLV59_RS15635	ENOG4105C6T	cysteine synthase
HLV59_RS15640	ENOG4105BZU	Histidine kinase
HLV59_RS15645	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HLV59_RS15655	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HLV59_RS15670	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HLV59_RS15675	ENOG4105W8H	transhydrogenase (subunit alpha
HLV59_RS15680	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HLV59_RS15685	ENOG4106UX7	integral membrane protein
HLV59_RS15700	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HLV59_RS15710	ENOG4107RSM	transcriptional regulator
HLV59_RS15720	ENOG4105CUZ	uba thif-type nad fad binding protein
HLV59_RS15725	ENOG4107QM5	aconitate hydratase
HLV59_RS15730	ENOG4105F8V	Hydrolase, tatD family
HLV59_RS15745	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HLV59_RS15760	ENOG4105BZU	Histidine kinase
HLV59_RS15765	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HLV59_RS15770	ENOG4108ZP8	Acetolactate synthase small subunit
HLV59_RS15775	ENOG4105C7K	acetolactate synthase
HLV59_RS15795	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HLV59_RS15800	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLV59_RS15805	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HLV59_RS15810	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HLV59_RS15820	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HLV59_RS15825	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HLV59_RS15835	ENOG4105VW4	glutaredoxin 3
HLV59_RS15855	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLV59_RS15860	ENOG4105C2D	reductase
HLV59_RS15870	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLV59_RS15900	ENOG4105C84	Histidine ammonia-lyase
HLV59_RS15910	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HLV59_RS15915	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS15930	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HLV59_RS15950	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HLV59_RS15970	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HLV59_RS15990	ENOG4105WVQ	Fe-S assembly protein IscX
HLV59_RS16005	ENOG4105CN1	protease
HLV59_RS16020	ENOG4106HB6	Alpha beta hydrolase
HLV59_RS16030	ENOG4105C26	Dehydrogenase
HLV59_RS16035	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HLV59_RS16040	ENOG4105C6Z	Gluconate
HLV59_RS16045	ENOG4108UHU	Aldolase
HLV59_RS16050	ENOG4105C01	Dihydroxy-acid dehydratase
HLV59_RS16060	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HLV59_RS16065	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HLV59_RS16070	ENOG4107GFK	fumarate
HLV59_RS16090	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HLV59_RS16100	ENOG4108ESX	Receptor
HLV59_RS16110	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HLV59_RS16120	ENOG4105DWV	Homoserine O-trans-acetylase
HLV59_RS16220	ENOG4105CIY	formyltetrahydrofolate deformylase
HLV59_RS16230	ENOG4107RGH	Aldehyde dehydrogenase
HLV59_RS16245	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HLV59_RS16265	ENOG4105VFU	Rna-binding protein
HLV59_RS16270	ENOG4105C4R	Atp-dependent dna helicase
HLV59_RS16285	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HLV59_RS16295	ENOG4105KVH	Transcriptional regulator
HLV59_RS16305	ENOG41069P5	Protein slyX homolog
HLV59_RS16310	ENOG4105C5H	ABC transporter
HLV59_RS16320	ENOG4105D1S	lipid A biosynthesis
HLV59_RS16330	ENOG4105CK2	sodium dicarboxylate symporter
HLV59_RS16385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLV59_RS16435	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HLV59_RS16450	ENOG4108W5M	transcriptional regulator
HLV59_RS16465	ENOG4105D29	Helix-turn-helix type 11 domain protein
HLV59_RS16470	ENOG4107XGZ	Hydrolase
HLV59_RS16475	ENOG4105EI2	Pseudouridine synthase
HLV59_RS16480	ENOG4107QQB	Ribonuclease E
HLV59_RS16485	ENOG4105J5T	Amp-dependent synthetase and ligase
HLV59_RS16500	ENOG4105CBN	LysR family transcriptional regulator
HLV59_RS16505	ENOG4105EMU	Dehydrogenase
HLV59_RS16510	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLV59_RS16520	ENOG4107QI1	Mate efflux family protein
HLV59_RS16530	ENOG4107T8P	acyl-Coa dehydrogenase
HLV59_RS16560	ENOG4105BZ8	glutamate synthase
HLV59_RS16570	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HLV59_RS16575	ENOG4105C5X	domain protein
HLV59_RS16590	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLV59_RS16600	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HLV59_RS16610	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HLV59_RS16615	ENOG4108JU5	Magnesium and cobalt efflux protein
HLV59_RS16620	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HLV59_RS16625	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HLV59_RS16635	ENOG4108VAU	general secretion pathway protein G
HLV59_RS16640	ENOG4105D7Q	type ii secretion system
HLV59_RS16645	ENOG4105C25	Primosomal protein n'
HLV59_RS16655	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HLV59_RS16665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HLV59_RS16670	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HLV59_RS16675	ENOG4107QUT	magnesium and cobalt transport protein CorA
HLV59_RS16680	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HLV59_RS16695	ENOG4107QYX	exodeoxyribonuclease v alpha
HLV59_RS16700	ENOG4107QKA	exodeoxyribonuclease V beta
HLV59_RS16705	ENOG4105DSY	exodeoxyribonuclease V, gamma
HLV59_RS16715	ENOG4105CSR	polyphosphate kinase 2
HLV59_RS16725	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLV59_RS16735	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HLV59_RS16745	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HLV59_RS16760	ENOG4105D65	subunit l
HLV59_RS16765	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HLV59_RS16770	ENOG4107R4Z	monovalent cation h antiporter subunit d
HLV59_RS16775	ENOG4105SC1	monovalent cation H antiporter subunit E
HLV59_RS16780	ENOG4105W4C	monovalent cation H antiporter subunit F
HLV59_RS16785	ENOG4105KJM	monovalent cation h antiporter subunit g
HLV59_RS16790	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HLV59_RS16800	ENOG4105CHV	Transcription elongation factor NusA
HLV59_RS16825	ENOG4107EJC	Preprotein translocase subunit SecG
HLV59_RS16835	ENOG4107QHF	type ii secretion system protein e
HLV59_RS16850	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HLV59_RS16860	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HLV59_RS16875	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HLV59_RS16885	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HLV59_RS16920	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HLV59_RS16925	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HLV59_RS16985	ENOG4108Z6Z	Transcriptional regulator
HLV59_RS16995	ENOG4107ZXU	DSBA oxidoreductase
HLV59_RS17010	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HLV59_RS17025	ENOG4105D3Y	Na H antiporter
HLV59_RS17080	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HLV59_RS17085	ENOG4105PM1	preprotein translocase subunit SecE
HLV59_RS17095	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HLV59_RS17125	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HLV59_RS17130	ENOG4105TV9	FHA Domain-Containing protein
HLV59_RS17135	ENOG4105GVR	general secretion pathway protein D
HLV59_RS17150	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
HLV59_RS17175	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HLV59_RS17180	ENOG4108NEV	two component transcriptional regulator, LytTR family
HLV59_RS17185	ENOG4108HRK	Histidine kinase
HLV59_RS17200	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HLV59_RS17205	ENOG4105DFG	type I secretion outer membrane protein
HLV59_RS17215	ENOG4108RNG	Permease of the drug metabolite transporter
HLV59_RS17235	ENOG41087AY	ADP-Ribose pyrophosphatase
HLV59_RS17240	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HLV59_RS17250	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HLV59_RS17255	ENOG4105CNI	cell division protein FtsW
HLV59_RS17270	ENOG4105CE1	Ferrous iron transport protein b
HLV59_RS17280	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLV59_RS17285	ENOG4105T95	Thiol disulfide interChange protein
HLV59_RS17290	ENOG4105D6E	homoserine dehydrogenase
HLV59_RS17300	ENOG41061WM	D-Alanyl-D-Alanine
HLV59_RS17310	ENOG4107TUY	Histidine kinase
HLV59_RS17315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HLV59_RS17320	ENOG4105CN1	protease
HLV59_RS17325	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HLV59_RS17330	ENOG4108K5H	permease YjgP YjgQ family protein
HLV59_RS17335	ENOG4108M8S	permease YjgP YjgQ family protein
HLV59_RS17370	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HLV59_RS17380	ENOG4105BZU	Histidine kinase
HLV59_RS17395	ENOG4105C0P	Mg chelatase subunit ChlI
HLV59_RS17400	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLV59_RS17405	ENOG4105FB2	class II Aldolase
HLV59_RS17410	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLV59_RS17425	ENOG4105EPF	Outer membrane porin
HLV59_RS17430	ENOG4105F0N	pyrophosphate phospho-hydrolase
HLV59_RS17445	ENOG4105CEY	Amp-dependent synthetase and ligase
HLV59_RS17450	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLV59_RS17455	ENOG41079KZ	Major Facilitator Superfamily
HLV59_RS17460	ENOG4105EN6	Membrane
HLV59_RS17465	ENOG4105K5B	UPF0225 protein
HLV59_RS17470	ENOG4105EE5	Membrane protein terC
HLV59_RS17475	ENOG4108URH	decarboxylase
HLV59_RS17485	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLV59_RS17495	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HLV59_RS17510	ENOG4105CCT	upf0313 protein
HLV59_RS17530	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HLV59_RS17540	ENOG4105C6T	cysteine synthase
HLV59_RS17545	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HLV59_RS17575	ENOG4105Y7M	Transcriptional regulator, TetR family
HLV59_RS17610	ENOG4105C79	DNA protecting protein DprA
HLV59_RS17625	ENOG4108IND	Tetr family transcriptional regulator
HLV59_RS17630	ENOG4107RTG	Major Facilitator superfamily
HLV59_RS17640	ENOG4108V06	Glutathione peroxidase
HLV59_RS17650	ENOG41090VV	Protein of unknown function (DUF2846)
HLV59_RS17660	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HLV59_RS17670	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HLV59_RS17710	ENOG4105FDK	ABC transporter
HLV59_RS17715	ENOG4105FAV	ABC, transporter
HLV59_RS17720	ENOG410829K	Lysine exporter protein (Lyse ygga)
HLV59_RS17725	ENOG4105EZR	dyp-type peroxidase family protein
HLV59_RS17730	ENOG4107R1I	NAD-dependent malic enzyme
HLV59_RS17755	ENOG4105EUB	pirin domain protein
HLV59_RS17760	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HLV59_RS17765	ENOG4106MP8	UPF0754 membrane protein
HLV59_RS17770	ENOG4108VBZ	doxx family
HLV59_RS17775	ENOG4105DQR	SNARE associated Golgi
HLV59_RS17790	ENOG4107QJE	Chromosome Partitioning Protein
HLV59_RS17800	ENOG4107PSF	BolA-like protein
HLV59_RS17845	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS17850	ENOG4107RCI	amp-dependent synthetase and ligase
HLV59_RS17870	ENOG4105CSH	Transporter
HLV59_RS17875	ENOG4105E39	Enoyl-CoA hydratase
HLV59_RS17880	ENOG4105E39	Enoyl-CoA hydratase
HLV59_RS17885	ENOG4105C1G	acyl-Coa dehydrogenase
HLV59_RS17895	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HLV59_RS17900	ENOG4105C26	Dehydrogenase
HLV59_RS17930	ENOG4105C85	amino acid
HLV59_RS17935	ENOG4105C85	amino acid
HLV59_RS17940	ENOG4105M4H	endoribonuclease L-psp
HLV59_RS17955	ENOG4105EW9	transcriptional regulator AsnC family
HLV59_RS17980	ENOG4105D3G	Pseudouridine synthase
HLV59_RS18055	ENOG4108I0Z	Aconitate hydratase
HLV59_RS18060	ENOG4105BZN	citrate synthase
HLV59_RS18065	ENOG4105CR4	methylisocitrate lyase
HLV59_RS18070	ENOG4105DRR	Transcriptional regulator, GntR family
HLV59_RS18080	ENOG4105CGF	Aromatic amino acid aminotransferase
HLV59_RS18085	ENOG4105CXG	d-lactate dehydrogenase
HLV59_RS18095	ENOG41073TP	transcriptional regulator
HLV59_RS18100	ENOG4105DAA	L-lactate
HLV59_RS18105	ENOG4107QKV	phosphomannomutase
HLV59_RS18110	ENOG4105CMR	udp-glucose 4-epimerase
HLV59_RS18120	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HLV59_RS18125	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HLV59_RS18135	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HLV59_RS18140	ENOG4107WZ3	Transferase
HLV59_RS18145	ENOG4105D3Q	Sugar transferase
HLV59_RS18185	ENOG4107QQG	Dehydrogenase
HLV59_RS18190	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HLV59_RS18195	ENOG4107QQG	Dehydrogenase
HLV59_RS18200	ENOG4105DAY	polysaccharide export protein
HLV59_RS18210	ENOG4105D75	Capsular exopolysaccharide family
HLV59_RS18215	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HLV59_RS18220	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HLV59_RS18225	ENOG4105CJR	Integral membrane protein (MviN
HLV59_RS18230	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HLV59_RS18235	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HLV59_RS18245	ENOG4105HSS	phospholipase C
HLV59_RS18265	ENOG4105EJ2	Transcriptional regulator
HLV59_RS18270	ENOG41062JF	Transcriptional regulator
HLV59_RS18275	ENOG4108Z33	Thiol disulfide Interchange Protein
HLV59_RS18285	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HLV59_RS18290	ENOG4105UBK	short-chain dehydrogenase reductase
HLV59_RS18305	ENOG4107QZM	n-acetylglutamate synthase
HLV59_RS18310	ENOG4105GVF	(ABC) transporter
HLV59_RS18315	ENOG4105GVF	(ABC) transporter
HLV59_RS18320	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HLV59_RS18325	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HLV59_RS18330	ENOG4108VM9	ABC, transporter
HLV59_RS18335	ENOG4108R86	Transcriptional regulator
HLV59_RS18340	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HLV59_RS18350	ENOG4105DTN	riboflavin biosynthesis protein ribF
HLV59_RS18355	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HLV59_RS18365	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HLV59_RS18405	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HLV59_RS18460	ENOG4105CVE	Lytic murein transglycosylase
HLV59_RS18465	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HLV59_RS18470	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HLV59_RS18485	ENOG4105DFU	Cell wall formation (By similarity)
HLV59_RS18495	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HLV59_RS18500	ENOG4105DU1	integral membrane protein, terc
HLV59_RS18510	ENOG4106032	Glutathionylspermidine synthase
HLV59_RS18520	ENOG4107QUY	Guanine deaminase
HLV59_RS18525	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HLV59_RS18535	ENOG4105T95	Thiol disulfide interChange protein
HLV59_RS18540	ENOG4105PGM	cation diffusion facilitator family transporter
HLV59_RS18555	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins