locus-tag	class	description
BFG52_RS00010	COG0592	DNA-directed DNA polymerase activity
BFG52_RS00020	COG0187	DNA topoisomerase II activity
BFG52_RS00035	COG0574	Belongs to the PEP-utilizing enzyme family
BFG52_RS00035	COG3848	Pyruvate phosphate dikinase
BFG52_RS00050	COG0488	(ABC) transporter
BFG52_RS00060	COG2197	response regulator
BFG52_RS00065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFG52_RS00075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFG52_RS00080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BFG52_RS00085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFG52_RS00130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFG52_RS00155	COG3738	Protein conserved in bacteria
BFG52_RS00160	COG0733	neurotransmitter:sodium symporter activity
BFG52_RS00165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFG52_RS00165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFG52_RS00175	COG0129	dihydroxy-acid dehydratase activity
BFG52_RS00195	COG2814	Major facilitator Superfamily
BFG52_RS00210	COG0583	DNA-binding transcription factor activity
BFG52_RS00215	COG2233	PERMEase
BFG52_RS00230	COG0484	heat shock protein binding
BFG52_RS00245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFG52_RS00250	COG2818	Glycosylase
BFG52_RS00265	COG1194	a g-specific adenine glycosylase
BFG52_RS00285	COG2983	Belongs to the UPF0260 family
BFG52_RS00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFG52_RS00295	COG2226	methyltransferase
BFG52_RS00315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFG52_RS00325	COG0657	acetylesterase activity
BFG52_RS00330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFG52_RS00365	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BFG52_RS00375	COG0671	phosphoesterase, PA-phosphatase related
BFG52_RS00375	COG2453	phosphatase
BFG52_RS00380	COG2267	carboxylic ester hydrolase activity
BFG52_RS00385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFG52_RS00390	COG1047	Peptidyl-prolyl cis-trans
BFG52_RS00400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFG52_RS00405	COG0196	riboflavin kinase activity
BFG52_RS00410	COG1309	transcriptional regulator
BFG52_RS00415	COG1116	anion transmembrane transporter activity
BFG52_RS00420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFG52_RS00425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFG52_RS00430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFG52_RS00435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFG52_RS00435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BFG52_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS00450	COG0546	phosphoglycolate phosphatase activity
BFG52_RS00455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFG52_RS00465	COG1309	transcriptional regulator
BFG52_RS00475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BFG52_RS00490	COG3023	N-Acetylmuramoyl-L-alanine amidase
BFG52_RS00520	COG1596	polysaccharide export
BFG52_RS00530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BFG52_RS00540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFG52_RS00565	COG0438	transferase activity, transferring glycosyl groups
BFG52_RS00580	COG0438	transferase activity, transferring glycosyl groups
BFG52_RS00580	COG0297	glycogen (starch) synthase activity
BFG52_RS00585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFG52_RS00590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFG52_RS00605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFG52_RS00610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFG52_RS00615	COG0281	malic enzyme
BFG52_RS00645	COG1132	(ABC) transporter
BFG52_RS00650	COG1538	Outer membrane efflux protein
BFG52_RS00670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BFG52_RS00675	COG0022	dehydrogenase e1 component
BFG52_RS00680	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFG52_RS00685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFG52_RS00710	COG3121	Chaperone
BFG52_RS00805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFG52_RS00830	COG0625	glutathione transferase activity
BFG52_RS00840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFG52_RS00845	COG1473	amidohydrolase
BFG52_RS00850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFG52_RS00865	COG0765	amino acid transport
BFG52_RS00870	COG1126	abc transporter atp-binding protein
BFG52_RS00880	COG1278	Cold shock
BFG52_RS00925	COG1289	transmembrane transporter activity
BFG52_RS00940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFG52_RS00950	COG0765	amino acid transport
BFG52_RS00960	COG1126	abc transporter atp-binding protein
BFG52_RS00965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFG52_RS00975	COG0497	DNA recombination
BFG52_RS00980	COG3123	guanosine phosphorylase activity
BFG52_RS00985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFG52_RS00995	COG0237	dephospho-CoA kinase activity
BFG52_RS01000	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BFG52_RS01005	COG1459	type II secretion system
BFG52_RS01040	COG0779	Required for maturation of 30S ribosomal subunits
BFG52_RS01045	COG0195	Participates in both transcription termination and antitermination
BFG52_RS01060	COG1704	LemA family
BFG52_RS01065	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BFG52_RS01085	COG3307	-O-antigen
BFG52_RS01110	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BFG52_RS01120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BFG52_RS01130	COG0778	Nitroreductase
BFG52_RS01135	COG0697	spore germination
BFG52_RS01140	COG1846	Transcriptional regulator
BFG52_RS01155	COG2837	iron assimilation
BFG52_RS01160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFG52_RS01165	COG1121	(ABC) transporter
BFG52_RS01170	COG0735	belongs to the Fur family
BFG52_RS01290	COG0582	viral genome integration into host DNA
BFG52_RS01300	COG3158	transport of potassium into the cell
BFG52_RS01325	COG0107	imidazoleglycerol-phosphate synthase activity
BFG52_RS01330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BFG52_RS01360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFG52_RS01390	COG0427	acetyl-CoA hydrolase
BFG52_RS01410	COG4221	oxidoreductase activity
BFG52_RS01415	COG2873	o-acetylhomoserine
BFG52_RS01420	COG0488	(ABC) transporter
BFG52_RS01450	COG0228	four-way junction DNA binding
BFG52_RS01455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFG52_RS01470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BFG52_RS01475	COG5380	lipid catabolic process
BFG52_RS01480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFG52_RS01510	COG0697	spore germination
BFG52_RS01520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFG52_RS01525	COG0277	FAD linked oxidase domain protein
BFG52_RS01540	COG1132	(ABC) transporter
BFG52_RS01545	COG1132	(ABC) transporter
BFG52_RS01550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFG52_RS01580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BFG52_RS01585	COG1074	ATP-dependent DNA helicase activity
BFG52_RS01590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFG52_RS01605	COG0598	Magnesium transport protein CorA
BFG52_RS01625	COG0640	Transcriptional regulator
BFG52_RS01650	COG0789	Transcriptional regulator
BFG52_RS01660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFG52_RS01670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFG52_RS01690	COG3293	Transposase
BFG52_RS01700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BFG52_RS01705	COG4535	Mg2 and Co2 transporter CorC
BFG52_RS01710	COG0425	Belongs to the sulfur carrier protein TusA family
BFG52_RS01715	COG0488	(ABC) transporter
BFG52_RS01720	COG2900	Belongs to the SlyX family
BFG52_RS01755	COG0583	DNA-binding transcription factor activity
BFG52_RS01780	COG0473	3-isopropylmalate dehydrogenase activity
BFG52_RS01815	COG1560	Kdo2-lipid A biosynthetic process
BFG52_RS01820	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BFG52_RS01820	COG0644	oxidoreductase
BFG52_RS01830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFG52_RS01845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFG52_RS01850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BFG52_RS01870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFG52_RS01875	COG0534	Mate efflux family protein
BFG52_RS01880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFG52_RS01890	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS01910	COG0408	coproporphyrinogen oxidase activity
BFG52_RS01940	COG1127	ABC transporter
BFG52_RS01945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFG52_RS01950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFG52_RS01965	COG0598	Magnesium transport protein CorA
BFG52_RS01975	COG2816	NAD+ diphosphatase activity
BFG52_RS01980	COG1040	competence protein
BFG52_RS01985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFG52_RS02010	COG2937	Belongs to the GPAT DAPAT family
BFG52_RS02015	COG1946	Acyl-CoA thioesterase
BFG52_RS02020	COG1301	dicarboxylic acid transport
BFG52_RS02040	COG1959	2 iron, 2 sulfur cluster binding
BFG52_RS02045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFG52_RS02045	COG1017	nitric oxide dioxygenase activity
BFG52_RS02055	COG0433	COG0433 Predicted ATPase
BFG52_RS02060	COG0626	cystathionine gamma-synthase activity
BFG52_RS02070	COG0051	transcription antitermination factor activity, RNA binding
BFG52_RS02075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFG52_RS02080	COG0088	Forms part of the polypeptide exit tunnel
BFG52_RS02125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFG52_RS02135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFG52_RS02145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFG52_RS02160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFG52_RS02180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFG52_RS02190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFG52_RS02195	COG0202	RNA polymerase activity
BFG52_RS02200	COG0203	ribosomal protein L17
BFG52_RS02205	COG2072	flavoprotein involved in K transport
BFG52_RS02210	COG1595	DNA-templated transcription, initiation
BFG52_RS02225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BFG52_RS02240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BFG52_RS02245	COG0339	signal peptide processing
BFG52_RS02250	COG0069	glutamate synthase activity
BFG52_RS02250	COG0070	glutamate synthase
BFG52_RS02250	COG0067	glutamate synthase
BFG52_RS02255	COG0493	'glutamate synthase
BFG52_RS02260	COG4770	biotin carboxylase activity
BFG52_RS02280	COG1914	H( )-stimulated, divalent metal cation uptake system
BFG52_RS02285	COG0583	DNA-binding transcription factor activity
BFG52_RS02310	COG3433	isochorismatase activity
BFG52_RS02310	COG2226	methyltransferase
BFG52_RS02310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFG52_RS02325	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BFG52_RS02340	COG4771	TonB-dependent receptor
BFG52_RS02350	COG0271	Belongs to the BolA IbaG family
BFG52_RS02360	COG1192	Involved in chromosome partitioning
BFG52_RS02375	COG0586	Pfam SNARE associated Golgi protein
BFG52_RS02380	COG2259	Doxx family
BFG52_RS02385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFG52_RS02385	COG0519	Catalyzes the synthesis of GMP from XMP
BFG52_RS02395	COG0596	Alpha beta hydrolase
BFG52_RS02425	COG2223	nitrite transmembrane transporter activity
BFG52_RS02430	COG0477	Major facilitator Superfamily
BFG52_RS02455	COG3121	Chaperone
BFG52_RS02490	COG0754	glutathionylspermidine amidase activity
BFG52_RS02510	COG1214	PFAM Peptidase M22, glycoprotease
BFG52_RS02515	COG1968	undecaprenyl-diphosphatase activity
BFG52_RS02520	COG0742	ribosomal rna small subunit methyltransferase
BFG52_RS02540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BFG52_RS02550	COG2132	Multicopper oxidase
BFG52_RS02560	COG1335	isochorismatase
BFG52_RS02570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BFG52_RS02570	COG0351	phosphomethylpyrimidine kinase
BFG52_RS02570	COG0352	thiamine-phosphate diphosphorylase activity
BFG52_RS02580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BFG52_RS02580	COG2755	lipolytic protein G-D-S-L family
BFG52_RS02585	COG1981	membrane
BFG52_RS02610	COG3831	ATPase activity
BFG52_RS02625	COG2197	response regulator
BFG52_RS02640	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BFG52_RS02650	COG0714	Associated with various cellular activities
BFG52_RS02685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFG52_RS02690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFG52_RS02695	COG0649	NAD binding
BFG52_RS02695	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFG52_RS02705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BFG52_RS02715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BFG52_RS02730	COG0713	ATP synthesis coupled electron transport
BFG52_RS02740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFG52_RS02750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFG52_RS02760	COG0583	DNA-binding transcription factor activity
BFG52_RS02765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFG52_RS02780	COG0668	transmembrane transport
BFG52_RS02790	COG2081	HI0933 family
BFG52_RS02815	COG2226	methyltransferase
BFG52_RS02825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFG52_RS02825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFG52_RS02835	COG0489	protein tyrosine kinase activity
BFG52_RS02845	COG0717	Belongs to the dCTP deaminase family
BFG52_RS02850	COG0442	prolyl-tRNA aminoacylation
BFG52_RS02865	COG5510	response to toxic substance
BFG52_RS02875	COG2832	Protein of unknown function (DUF454)
BFG52_RS02930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFG52_RS02940	COG1289	transmembrane transporter activity
BFG52_RS02945	COG2814	Major facilitator Superfamily
BFG52_RS02955	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFG52_RS02960	COG1607	acyl-coa hydrolase
BFG52_RS02970	COG4681	YaeQ
BFG52_RS02985	COG1215	transferase activity, transferring glycosyl groups
BFG52_RS02990	COG1649	PFAM Uncharacterised BCR, COG1649
BFG52_RS02990	COG0726	polysaccharide deacetylase
BFG52_RS03005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFG52_RS03015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFG52_RS03030	COG0730	response to heat
BFG52_RS03040	COG1196	nuclear chromosome segregation
BFG52_RS03050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFG52_RS03055	COG2193	ferroxidase activity
BFG52_RS03070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFG52_RS03075	COG0596	Alpha beta hydrolase
BFG52_RS03090	COG4106	trans-aconitate 2-methyltransferase activity
BFG52_RS03105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFG52_RS03110	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BFG52_RS03125	COG0009	L-threonylcarbamoyladenylate synthase
BFG52_RS03130	COG3101	peptidyl-lysine hydroxylation
BFG52_RS03135	COG1399	metal-binding, possibly nucleic acid-binding protein
BFG52_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS03170	COG0579	oxidoreductase
BFG52_RS03180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFG52_RS03210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BFG52_RS03225	COG2194	sulfuric ester hydrolase activity
BFG52_RS03230	COG2194	sulfuric ester hydrolase activity
BFG52_RS03240	COG0726	polysaccharide deacetylase
BFG52_RS03245	COG0463	Glycosyl transferase, family 2
BFG52_RS03260	COG1442	glycosyl transferase family 8
BFG52_RS03285	COG1215	transferase activity, transferring glycosyl groups
BFG52_RS03330	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS03335	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS03345	COG2205	protein histidine kinase activity
BFG52_RS03350	COG0745	RESPONSE REGULATOR receiver
BFG52_RS03355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BFG52_RS03370	COG2096	Adenosyltransferase
BFG52_RS03380	COG4206	TonB-dependent receptor
BFG52_RS03410	COG0183	Belongs to the thiolase family
BFG52_RS03425	COG1690	Belongs to the RtcB family
BFG52_RS03430	COG0833	amino acid
BFG52_RS03440	COG2233	PERMEase
BFG52_RS03455	COG0154	amidase activity
BFG52_RS03465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFG52_RS03475	COG1012	belongs to the aldehyde dehydrogenase family
BFG52_RS03480	COG3724	N-succinylarginine dihydrolase activity
BFG52_RS03485	COG2988	succinylglutamate desuccinylase activity
BFG52_RS03495	COG1970	mechanosensitive ion channel activity
BFG52_RS03500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFG52_RS03535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BFG52_RS03545	COG1297	OPT oligopeptide transporter protein
BFG52_RS03555	COG0564	pseudouridine synthase activity
BFG52_RS03570	COG0456	acetyltransferase
BFG52_RS03575	COG2824	Alkylphosphonate utilization operon protein PhnA
BFG52_RS03585	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BFG52_RS03590	COG3201	nicotinamide mononucleotide transporter
BFG52_RS03600	COG0306	phosphate transporter
BFG52_RS03620	COG4771	TonB-dependent receptor
BFG52_RS03665	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BFG52_RS03675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFG52_RS03700	COG2951	lytic endotransglycosylase activity
BFG52_RS03705	COG0772	Belongs to the SEDS family
BFG52_RS03710	COG3293	Transposase
BFG52_RS03725	COG0842	Transport permease protein
BFG52_RS03730	COG1131	(ABC) transporter
BFG52_RS03750	COG3723	Recombinational DNA repair protein, rece pathway
BFG52_RS03960	COG4771	TonB-dependent receptor
BFG52_RS03970	COG1570	exodeoxyribonuclease VII activity
BFG52_RS03975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BFG52_RS03980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFG52_RS03990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFG52_RS03995	COG1077	Cell shape determining protein MreB Mrl
BFG52_RS04000	COG1792	Involved in formation and maintenance of cell shape
BFG52_RS04005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BFG52_RS04010	COG0424	maF-like protein
BFG52_RS04015	COG1530	ribonuclease E activity
BFG52_RS04020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFG52_RS04055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BFG52_RS04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFG52_RS04070	COG0024	Methionine aminopeptidase
BFG52_RS04075	COG0052	Belongs to the universal ribosomal protein uS2 family
BFG52_RS04085	COG0477	Major facilitator Superfamily
BFG52_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS04105	COG0525	valine-tRNA ligase activity
BFG52_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS04120	COG0393	Putative heavy-metal-binding
BFG52_RS04125	COG0393	Putative heavy-metal-binding
BFG52_RS04130	COG1538	Outer membrane efflux protein
BFG52_RS04140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFG52_RS04160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFG52_RS04165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BFG52_RS04180	COG1648	precorrin-2 dehydrogenase activity
BFG52_RS04180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFG52_RS04185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BFG52_RS04190	COG0531	amino acid
BFG52_RS04205	COG0321	lipoyl(octanoyl) transferase activity
BFG52_RS04230	COG0500	methyltransferase
BFG52_RS04265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFG52_RS04270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFG52_RS04275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFG52_RS04285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BFG52_RS04295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFG52_RS04305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFG52_RS04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFG52_RS04340	COG2885	chlorophyll binding
BFG52_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
BFG52_RS04365	COG0824	Thioesterase
BFG52_RS04370	COG2255	four-way junction helicase activity
BFG52_RS04385	COG0047	phosphoribosylformylglycinamidine synthase activity
BFG52_RS04385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFG52_RS04390	COG0477	Major facilitator Superfamily
BFG52_RS04395	COG3323	Protein of unknown function (DUF1653)
BFG52_RS04395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFG52_RS04400	COG1024	Enoyl-CoA hydratase
BFG52_RS04405	COG1051	belongs to the nudix hydrolase family
BFG52_RS04405	COG1056	cytidyltransferase-related domain
BFG52_RS04410	COG0583	DNA-binding transcription factor activity
BFG52_RS04420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFG52_RS04430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFG52_RS04435	COG0602	queuosine metabolic process
BFG52_RS04440	COG2171	N-acyltransferase activity
BFG52_RS04450	COG0583	DNA-binding transcription factor activity
BFG52_RS04455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFG52_RS04460	COG4208	sulfate ABC transporter
BFG52_RS04465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BFG52_RS04475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BFG52_RS04485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFG52_RS04510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFG52_RS04530	COG4372	Transposase
BFG52_RS04550	COG3293	Transposase
BFG52_RS04560	COG1113	amino acid transport
BFG52_RS04565	COG1113	amino acid transport
BFG52_RS04570	COG2828	Protein conserved in bacteria
BFG52_RS04575	COG0142	geranyltranstransferase activity
BFG52_RS04580	COG0583	DNA-binding transcription factor activity
BFG52_RS04585	COG2267	carboxylic ester hydrolase activity
BFG52_RS04590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFG52_RS04595	COG1773	rubredoxin
BFG52_RS04625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFG52_RS04650	COG2851	Citrate transporter
BFG52_RS04655	COG1253	flavin adenine dinucleotide binding
BFG52_RS04675	COG2268	Band 7 protein
BFG52_RS04715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BFG52_RS04720	COG0505	Belongs to the CarA family
BFG52_RS04750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFG52_RS04755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BFG52_RS04760	COG2304	oxidoreductase activity
BFG52_RS04780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFG52_RS04785	COG2264	protein methyltransferase activity
BFG52_RS04795	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BFG52_RS04800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BFG52_RS04820	COG1595	DNA-templated transcription, initiation
BFG52_RS04830	COG4773	Receptor
BFG52_RS04835	COG4773	Receptor
BFG52_RS04870	COG4771	TonB-dependent receptor
BFG52_RS04885	COG4774	siderophore transport
BFG52_RS04905	COG0477	Major facilitator Superfamily
BFG52_RS04915	COG1595	DNA-templated transcription, initiation
BFG52_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS04940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BFG52_RS04950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFG52_RS04955	COG0477	Major facilitator Superfamily
BFG52_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS04970	COG1802	Transcriptional regulator
BFG52_RS04990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFG52_RS05020	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BFG52_RS05035	COG0358	DNA primase activity
BFG52_RS05045	COG0564	pseudouridine synthase activity
BFG52_RS05070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFG52_RS05090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFG52_RS05090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BFG52_RS05105	COG2009	succinate dehydrogenase
BFG52_RS05110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BFG52_RS05115	COG1053	succinate dehydrogenase
BFG52_RS05120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BFG52_RS05135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFG52_RS05145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFG52_RS05165	COG0742	ribosomal rna small subunit methyltransferase
BFG52_RS05170	COG0768	penicillin binding
BFG52_RS05195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFG52_RS05200	COG2878	Part of a membrane complex involved in electron transport
BFG52_RS05205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BFG52_RS05215	COG3384	dioxygenase
BFG52_RS05220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFG52_RS05230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFG52_RS05260	COG2031	fatty acid transporter
BFG52_RS05270	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BFG52_RS05275	COG3052	prosthetic group binding
BFG52_RS05295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BFG52_RS05365	COG0737	Belongs to the 5'-nucleotidase family
BFG52_RS05375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFG52_RS05385	COG1671	Belongs to the UPF0178 family
BFG52_RS05400	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFG52_RS05405	COG1136	(ABC) transporter
BFG52_RS05410	COG0658	competence protein
BFG52_RS05410	COG2333	competence protein COMEC
BFG52_RS05415	COG1560	Kdo2-lipid A biosynthetic process
BFG52_RS05430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFG52_RS05440	COG0628	permease
BFG52_RS05470	COG1720	tRNA m6t6A37 methyltransferase activity
BFG52_RS05485	COG0642	Histidine kinase
BFG52_RS05495	COG0494	nUDIX hydrolase
BFG52_RS05505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFG52_RS05510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFG52_RS05515	COG3139	Protein of unknown function (DUF1315)
BFG52_RS05525	COG1301	dicarboxylic acid transport
BFG52_RS05535	COG4521	taurine ABC transporter
BFG52_RS05540	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BFG52_RS05545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFG52_RS05550	COG2175	clavaminate synthase activity
BFG52_RS05560	COG5295	Hep Hag repeat protein
BFG52_RS05560	COG5295	Hep Hag repeat protein
BFG52_RS05575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFG52_RS05600	COG2814	Major facilitator Superfamily
BFG52_RS05615	COG4771	TonB-dependent receptor
BFG52_RS05620	COG3119	arylsulfatase activity
BFG52_RS05655	COG2239	Acts as a magnesium transporter
BFG52_RS05660	COG0501	Belongs to the peptidase M48B family
BFG52_RS05665	COG0739	heme binding
BFG52_RS05665	COG1196	nuclear chromosome segregation
BFG52_RS05665	COG0741	lytic transglycosylase activity
BFG52_RS05670	COG0037	tRNA processing
BFG52_RS05680	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFG52_RS05690	COG0477	Major facilitator Superfamily
BFG52_RS05695	COG0154	amidase activity
BFG52_RS05700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFG52_RS05760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFG52_RS05760	COG0517	IMP dehydrogenase activity
BFG52_RS05765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BFG52_RS05775	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BFG52_RS05780	COG1137	ATPase activity
BFG52_RS05790	COG3485	protocatechuate 3,4-dioxygenase
BFG52_RS05795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BFG52_RS05800	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BFG52_RS05810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFG52_RS05815	COG0183	Belongs to the thiolase family
BFG52_RS05820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BFG52_RS05825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BFG52_RS05830	COG4829	muconolactone delta-isomerase
BFG52_RS05835	COG4948	Mandelate Racemase Muconate Lactonizing
BFG52_RS05840	COG0583	DNA-binding transcription factor activity
BFG52_RS05845	COG1629	transport
BFG52_RS05855	COG1595	DNA-templated transcription, initiation
BFG52_RS05860	COG1129	ABC transporter
BFG52_RS05865	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFG52_RS05880	COG2807	transmembrane transport
BFG52_RS05885	COG2207	Transcriptional regulator
BFG52_RS05900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFG52_RS05905	COG1845	cytochrome c oxidase, subunit III
BFG52_RS05910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFG52_RS05915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BFG52_RS05945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BFG52_RS05955	COG0012	GTP binding
BFG52_RS05960	COG2011	ABC-type metal ion transport system permease component
BFG52_RS05965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFG52_RS05970	COG1464	Belongs to the NlpA lipoprotein family
BFG52_RS06040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFG52_RS06050	COG3178	'Phosphotransferase
BFG52_RS06055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BFG52_RS06065	COG1192	Involved in chromosome partitioning
BFG52_RS06070	COG1475	DNA binding
BFG52_RS06075	COG1132	(ABC) transporter
BFG52_RS06080	COG1663	tetraacyldisaccharide 4'-kinase activity
BFG52_RS06085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BFG52_RS06095	COG0084	hydrolase, TatD family'
BFG52_RS06120	COG3156	type II secretion system protein K
BFG52_RS06140	COG0590	tRNA wobble adenosine to inosine editing
BFG52_RS06150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFG52_RS06175	COG2431	L-lysine efflux transmembrane transporter activity
BFG52_RS06185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BFG52_RS06205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFG52_RS06215	COG2011	ABC-type metal ion transport system permease component
BFG52_RS06220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFG52_RS06235	COG0151	Belongs to the GarS family
BFG52_RS06240	COG0138	bifunctional purine biosynthesis protein purh
BFG52_RS06245	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BFG52_RS06290	COG3135	benzoate transporter
BFG52_RS06300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFG52_RS06305	COG0583	DNA-binding transcription factor activity
BFG52_RS06315	COG0183	Belongs to the thiolase family
BFG52_RS06330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFG52_RS06340	COG0443	Heat shock 70 kDa protein
BFG52_RS06345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BFG52_RS06365	COG0069	glutamate synthase activity
BFG52_RS06370	COG2850	peptidyl-arginine hydroxylation
BFG52_RS06375	COG0424	maF-like protein
BFG52_RS06395	COG3385	transposase activity
BFG52_RS06410	COG0697	spore germination
BFG52_RS06435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFG52_RS06465	COG1476	TRANSCRIPTIONal
BFG52_RS06495	COG0583	DNA-binding transcription factor activity
BFG52_RS06510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFG52_RS06515	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS06520	COG1024	Enoyl-CoA hydratase
BFG52_RS06525	COG1024	Enoyl-CoA hydratase
BFG52_RS06535	COG1063	alcohol dehydrogenase
BFG52_RS06540	COG3781	membrane
BFG52_RS06545	COG4607	ABC-type enterochelin transport system periplasmic component
BFG52_RS06550	COG4604	ABC transporter, ATP-binding protein
BFG52_RS06555	COG4605	iron ion homeostasis
BFG52_RS06560	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFG52_RS06565	COG1695	Transcriptional regulator
BFG52_RS06570	COG2375	cellular response to nickel ion
BFG52_RS06575	COG2814	Major facilitator Superfamily
BFG52_RS06605	COG4783	chaperone-mediated protein folding
BFG52_RS06610	COG1610	YqeY-like protein
BFG52_RS06630	COG1765	OsmC-like protein
BFG52_RS06640	COG0542	response to heat
BFG52_RS06665	COG0116	Belongs to the methyltransferase superfamily
BFG52_RS06665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFG52_RS06670	COG0540	Belongs to the ATCase OTCase family
BFG52_RS06690	COG1252	NADH dehydrogenase
BFG52_RS06695	COG1686	Belongs to the peptidase S11 family
BFG52_RS06720	COG2062	phosphohistidine phosphatase, SixA
BFG52_RS06755	COG2351	hydroxyisourate hydrolase activity
BFG52_RS06760	COG2233	PERMEase
BFG52_RS06765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFG52_RS06770	COG4266	Belongs to the allantoicase family
BFG52_RS06775	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BFG52_RS06800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BFG52_RS06805	COG0456	acetyltransferase
BFG52_RS06860	COG1132	(ABC) transporter
BFG52_RS06860	COG2375	cellular response to nickel ion
BFG52_RS06865	COG1132	(ABC) transporter
BFG52_RS06870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFG52_RS06875	COG4605	iron ion homeostasis
BFG52_RS06880	COG4604	ABC transporter, ATP-binding protein
BFG52_RS06885	COG4607	ABC-type enterochelin transport system periplasmic component
BFG52_RS06890	COG4774	siderophore transport
BFG52_RS06900	COG1309	transcriptional regulator
BFG52_RS06910	COG0579	oxidoreductase
BFG52_RS06925	COG4589	Belongs to the CDS family
BFG52_RS06935	COG0671	phosphoesterase, PA-phosphatase related
BFG52_RS06970	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BFG52_RS06980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFG52_RS07000	COG0443	Heat shock 70 kDa protein
BFG52_RS07010	COG0316	Belongs to the HesB IscA family
BFG52_RS07015	COG0822	iron-sulfur transferase activity
BFG52_RS07025	COG1959	2 iron, 2 sulfur cluster binding
BFG52_RS07040	COG0776	regulation of translation
BFG52_RS07045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFG52_RS07060	COG1215	transferase activity, transferring glycosyl groups
BFG52_RS07095	COG1595	DNA-templated transcription, initiation
BFG52_RS07120	COG0159	tryptophan synthase activity
BFG52_RS07150	COG2011	ABC-type metal ion transport system permease component
BFG52_RS07185	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BFG52_RS07185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFG52_RS07190	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BFG52_RS07205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BFG52_RS07210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BFG52_RS07375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFG52_RS07545	COG3561	AntA/AntB antirepressor
BFG52_RS07590	COG3385	transposase activity
BFG52_RS07605	COG3617	BRO family, N-terminal domain
BFG52_RS07745	COG0270	DNA (cytosine-5-)-methyltransferase activity
BFG52_RS07775	COG5410	chromosome segregation
BFG52_RS08085	COG3567	Phage-associated protein, HI1409 family
BFG52_RS08265	COG3293	Transposase
BFG52_RS08275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFG52_RS08315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFG52_RS08320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFG52_RS08325	COG1045	serine acetyltransferase
BFG52_RS08345	COG1228	amidohydrolase
BFG52_RS08350	COG0010	Belongs to the arginase family
BFG52_RS08355	COG2188	Transcriptional regulator
BFG52_RS08360	COG1595	DNA-templated transcription, initiation
BFG52_RS08375	COG4771	TonB-dependent receptor
BFG52_RS08380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFG52_RS08385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFG52_RS08395	COG3712	iron ion homeostasis
BFG52_RS08400	COG4771	TonB-dependent receptor
BFG52_RS08425	COG1045	serine acetyltransferase
BFG52_RS08435	COG0805	protein transport
BFG52_RS08460	COG2175	clavaminate synthase activity
BFG52_RS08465	COG0277	FAD linked oxidase domain protein
BFG52_RS08470	COG2841	Protein conserved in bacteria
BFG52_RS08475	COG1113	amino acid transport
BFG52_RS08480	COG0583	DNA-binding transcription factor activity
BFG52_RS08485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFG52_RS08490	COG1012	belongs to the aldehyde dehydrogenase family
BFG52_RS08505	COG0789	Transcriptional regulator
BFG52_RS08515	COG0583	DNA-binding transcription factor activity
BFG52_RS08535	COG0583	DNA-binding transcription factor activity
BFG52_RS08550	COG0488	(ABC) transporter
BFG52_RS08555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFG52_RS08560	COG0583	DNA-binding transcription factor activity
BFG52_RS08580	COG3386	PFAM SMP-30 Gluconolaconase
BFG52_RS08585	COG1132	(ABC) transporter
BFG52_RS08590	COG2030	dehydratase
BFG52_RS08595	COG0509	glycine decarboxylation via glycine cleavage system
BFG52_RS08600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BFG52_RS08615	COG0596	Alpha beta hydrolase
BFG52_RS08620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFG52_RS08625	COG2808	Putative FMN-binding domain
BFG52_RS08640	COG1595	DNA-templated transcription, initiation
BFG52_RS08680	COG0583	DNA-binding transcription factor activity
BFG52_RS08685	COG1522	sequence-specific DNA binding
BFG52_RS08700	COG3293	Transposase
BFG52_RS08715	COG0360	Binds together with S18 to 16S ribosomal RNA
BFG52_RS08720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFG52_RS08730	COG0308	aminopeptidase N
BFG52_RS08760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFG52_RS08765	COG0730	response to heat
BFG52_RS08780	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BFG52_RS08790	COG1733	regulation of RNA biosynthetic process
BFG52_RS08815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFG52_RS08825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFG52_RS08835	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BFG52_RS08840	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BFG52_RS08860	COG0386	Belongs to the glutathione peroxidase family
BFG52_RS08870	COG0702	epimerase
BFG52_RS08875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFG52_RS08880	COG0436	Aminotransferase
BFG52_RS08925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFG52_RS08930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFG52_RS08955	COG1595	DNA-templated transcription, initiation
BFG52_RS08960	COG3712	iron ion homeostasis
BFG52_RS09020	COG0582	viral genome integration into host DNA
BFG52_RS09065	COG1187	pseudouridine synthase activity
BFG52_RS09070	COG0513	Belongs to the DEAD box helicase family
BFG52_RS09090	COG2363	Small membrane protein
BFG52_RS09105	COG1629	transport
BFG52_RS09110	COG1629	transport
BFG52_RS09125	COG1643	Atp-dependent helicase
BFG52_RS09130	COG0174	glutamine synthetase
BFG52_RS09140	COG1923	regulation of RNA biosynthetic process
BFG52_RS09150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFG52_RS09155	COG0802	atpase or kinase
BFG52_RS09170	COG1187	pseudouridine synthase activity
BFG52_RS09180	COG0583	DNA-binding transcription factor activity
BFG52_RS09185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFG52_RS09190	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BFG52_RS09195	COG2814	Major facilitator Superfamily
BFG52_RS09200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFG52_RS09205	COG1113	amino acid transport
BFG52_RS09215	COG3539	Fimbrial protein
BFG52_RS09220	COG3121	Chaperone
BFG52_RS09250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFG52_RS09260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFG52_RS09280	COG3122	Protein conserved in bacteria
BFG52_RS09285	COG0583	DNA-binding transcription factor activity
BFG52_RS09295	COG1346	cytolysis
BFG52_RS09300	COG0668	transmembrane transport
BFG52_RS09310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFG52_RS09320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFG52_RS09330	COG0506	proline dehydrogenase activity
BFG52_RS09330	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BFG52_RS09330	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BFG52_RS09350	COG0024	Methionine aminopeptidase
BFG52_RS09365	COG0729	surface antigen
BFG52_RS09370	COG0477	Major facilitator Superfamily
BFG52_RS09380	COG0745	RESPONSE REGULATOR receiver
BFG52_RS09385	COG1595	DNA-templated transcription, initiation
BFG52_RS09400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFG52_RS09425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFG52_RS09455	COG0537	adenosine 5'-monophosphoramidase activity
BFG52_RS09525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BFG52_RS09535	COG1733	regulation of RNA biosynthetic process
BFG52_RS09550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BFG52_RS09555	COG4149	molybdate abc transporter
BFG52_RS09560	COG0725	ABC transporter, periplasmic molybdate-binding protein
BFG52_RS09565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFG52_RS09570	COG0314	molybdopterin synthase activity
BFG52_RS09585	COG0303	'Molybdopterin
BFG52_RS09590	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFG52_RS09590	COG0315	cyclic pyranopterin monophosphate synthase activity
BFG52_RS09595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BFG52_RS09650	COG3328	transposase activity
BFG52_RS09670	COG3210	domain, Protein
BFG52_RS09685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BFG52_RS09695	COG4122	O-methyltransferase activity
BFG52_RS09715	COG3293	Transposase
BFG52_RS09720	COG5295	Hep Hag repeat protein
BFG52_RS09735	COG1113	amino acid transport
BFG52_RS09745	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS09790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFG52_RS09800	COG0848	biopolymer transport protein
BFG52_RS09815	COG4178	(ABC) transporter
BFG52_RS09835	COG4206	TonB-dependent receptor
BFG52_RS09835	COG1629	transport
BFG52_RS09855	COG0552	protein localization to endoplasmic reticulum
BFG52_RS09860	COG0612	Peptidase, M16
BFG52_RS09885	COG0517	IMP dehydrogenase activity
BFG52_RS09925	COG0556	nucleotide-excision repair
BFG52_RS09940	COG0436	Aminotransferase
BFG52_RS09965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BFG52_RS09970	COG3161	chorismate lyase activity
BFG52_RS09980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFG52_RS10000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFG52_RS10015	COG0575	Belongs to the CDS family
BFG52_RS10020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFG52_RS10025	COG0233	cytoplasmic translational termination
BFG52_RS10040	COG3852	Histidine kinase
BFG52_RS10045	COG2204	response regulator
BFG52_RS10050	COG0372	Belongs to the citrate synthase family
BFG52_RS10075	COG0542	response to heat
BFG52_RS10080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BFG52_RS10090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFG52_RS10110	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BFG52_RS10135	COG0511	ligase activity, forming carbon-carbon bonds
BFG52_RS10165	COG4232	protein-disulfide reductase activity
BFG52_RS10180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BFG52_RS10205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFG52_RS10225	COG1011	Hydrolase
BFG52_RS10230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BFG52_RS10240	COG2137	regulation of response to DNA damage stimulus
BFG52_RS10255	COG0305	Participates in initiation and elongation during chromosome replication
BFG52_RS10260	COG4774	siderophore transport
BFG52_RS10270	COG2197	response regulator
BFG52_RS10275	COG4585	Histidine kinase
BFG52_RS10305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BFG52_RS10320	COG1566	PFAM secretion protein HlyD family protein
BFG52_RS10340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFG52_RS10345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFG52_RS10350	COG1309	transcriptional regulator
BFG52_RS10365	COG1115	amino acid carrier protein
BFG52_RS10385	COG2207	Transcriptional regulator
BFG52_RS10390	COG0243	molybdopterin cofactor binding
BFG52_RS10395	COG2223	nitrite transmembrane transporter activity
BFG52_RS10435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFG52_RS10450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFG52_RS10475	COG0569	domain protein
BFG52_RS10480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFG52_RS10495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFG52_RS10505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFG52_RS10520	COG0505	Belongs to the CarA family
BFG52_RS10525	COG0477	Major facilitator Superfamily
BFG52_RS10535	COG0500	methyltransferase
BFG52_RS10570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFG52_RS10575	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS10580	COG0583	DNA-binding transcription factor activity
BFG52_RS10595	COG0583	DNA-binding transcription factor activity
BFG52_RS10600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFG52_RS10620	COG1294	oxidase, subunit
BFG52_RS10625	COG4890	Cyd operon protein YbgT
BFG52_RS10645	COG4122	O-methyltransferase activity
BFG52_RS10655	COG3634	alkyl hydroperoxide reductase activity
BFG52_RS10660	COG1473	amidohydrolase
BFG52_RS10665	COG0477	Major facilitator Superfamily
BFG52_RS10685	COG2070	2-Nitropropane dioxygenase
BFG52_RS10765	COG2807	transmembrane transport
BFG52_RS10775	COG0561	phosphatase activity
BFG52_RS10790	COG2814	Major facilitator Superfamily
BFG52_RS10820	COG0019	diaminopimelate decarboxylase activity
BFG52_RS10830	COG1535	isochorismatase
BFG52_RS10830	COG3433	isochorismatase activity
BFG52_RS10835	COG1021	2,3-dihydroxybenzoate-AMP ligase
BFG52_RS10840	COG1169	isochorismate synthase
BFG52_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS10890	COG1902	pentaerythritol trinitrate reductase activity
BFG52_RS10890	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFG52_RS10895	COG3739	integral membrane protein
BFG52_RS10925	COG0302	gtp cyclohydrolase
BFG52_RS10940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFG52_RS10945	COG0512	Glutamine amidotransferase of anthranilate synthase
BFG52_RS10980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFG52_RS11020	COG2871	sodium ion transport
BFG52_RS11030	COG1283	sodium-dependent phosphate transmembrane transporter activity
BFG52_RS11125	COG1304	FMN binding
BFG52_RS11165	COG0028	Belongs to the TPP enzyme family
BFG52_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS11185	COG0596	Alpha beta hydrolase
BFG52_RS11195	COG2271	Major facilitator Superfamily
BFG52_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS11240	COG1741	Belongs to the pirin family
BFG52_RS11250	COG0418	dihydroorotase activity
BFG52_RS11255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFG52_RS11260	COG0833	amino acid
BFG52_RS11265	COG0833	amino acid
BFG52_RS11295	COG2814	Major facilitator Superfamily
BFG52_RS11310	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFG52_RS11310	COG1902	pentaerythritol trinitrate reductase activity
BFG52_RS11315	COG4172	Belongs to the ABC transporter superfamily
BFG52_RS11320	COG4239	(ABC) transporter, permease
BFG52_RS11325	COG4174	ABC transporter (Permease)
BFG52_RS11330	COG4166	transmembrane transport
BFG52_RS11335	COG1388	LysM domain
BFG52_RS11335	COG1388	LysM domain
BFG52_RS11335	COG0741	lytic transglycosylase activity
BFG52_RS11335	COG0741	lytic transglycosylase activity
BFG52_RS11375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFG52_RS11380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFG52_RS11385	COG0006	proline dipeptidase activity
BFG52_RS11490	COG3293	Transposase
BFG52_RS11500	COG0527	aspartate kinase activity
BFG52_RS11510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFG52_RS11515	COG3038	cytochrome b561
BFG52_RS11520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFG52_RS11525	COG2252	PERMEase
BFG52_RS11550	COG1566	PFAM secretion protein HlyD family protein
BFG52_RS11555	COG2814	Major facilitator Superfamily
BFG52_RS11585	COG1271	oxidase subunit
BFG52_RS11590	COG1294	oxidase, subunit
BFG52_RS11595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFG52_RS11620	COG1309	transcriptional regulator
BFG52_RS11625	COG1280	lysine exporter protein (LysE YggA)
BFG52_RS11635	COG4772	TonB-dependent receptor
BFG52_RS11650	COG4993	Dehydrogenase
BFG52_RS11655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BFG52_RS11720	COG0612	Peptidase, M16
BFG52_RS11740	COG1823	symporter activity
BFG52_RS11750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFG52_RS11765	COG2879	small protein
BFG52_RS11770	COG1966	Carbon starvation protein
BFG52_RS11780	COG1509	lysine 2,3-aminomutase activity
BFG52_RS11830	COG2211	Major facilitator Superfamily
BFG52_RS11835	COG1067	ATP-dependent peptidase activity
BFG52_RS11840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFG52_RS11845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BFG52_RS11850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFG52_RS11855	COG0583	DNA-binding transcription factor activity
BFG52_RS11870	COG1686	Belongs to the peptidase S11 family
BFG52_RS11920	COG3539	Fimbrial protein
BFG52_RS11925	COG0616	signal peptide processing
BFG52_RS11930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFG52_RS11940	COG0573	inorganic phosphate transmembrane transporter activity
BFG52_RS11945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BFG52_RS11950	COG0076	glutamate decarboxylase activity
BFG52_RS11955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFG52_RS11975	COG1309	transcriptional regulator
BFG52_RS12010	COG0564	pseudouridine synthase activity
BFG52_RS12030	COG0352	thiamine-phosphate diphosphorylase activity
BFG52_RS12040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BFG52_RS12060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFG52_RS12100	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BFG52_RS12105	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BFG52_RS12120	COG1113	amino acid transport
BFG52_RS12135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFG52_RS12140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFG52_RS12145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFG52_RS12170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BFG52_RS12175	COG1381	Involved in DNA repair and RecF pathway recombination
BFG52_RS12185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BFG52_RS12190	COG0571	ribonuclease III activity
BFG52_RS12205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFG52_RS12210	COG5383	Protein conserved in bacteria
BFG52_RS12215	COG1301	dicarboxylic acid transport
BFG52_RS12220	COG0583	DNA-binding transcription factor activity
BFG52_RS12225	COG0277	FAD linked oxidase domain protein
BFG52_RS12225	COG0247	lactate metabolic process
BFG52_RS12240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BFG52_RS12245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BFG52_RS12250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFG52_RS12260	COG0281	malic enzyme
BFG52_RS12260	COG0280	phosphate acetyltransferase
BFG52_RS12270	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BFG52_RS12275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFG52_RS12305	COG4774	siderophore transport
BFG52_RS12315	COG5002	protein histidine kinase activity
BFG52_RS12325	COG1396	sequence-specific DNA binding
BFG52_RS12335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BFG52_RS12340	COG2814	Major facilitator Superfamily
BFG52_RS12350	COG2050	protein possibly involved in aromatic compounds catabolism
BFG52_RS12380	COG0642	Histidine kinase
BFG52_RS12385	COG0745	RESPONSE REGULATOR receiver
BFG52_RS12395	COG2814	Major facilitator Superfamily
BFG52_RS12405	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFG52_RS12455	COG0420	3'-5' exonuclease activity
BFG52_RS12480	COG0735	belongs to the Fur family
BFG52_RS12485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFG52_RS12490	COG2914	Belongs to the UPF0125 (RnfH) family
BFG52_RS12500	COG0121	glutamine amidotransferase
BFG52_RS12515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFG52_RS12520	COG0307	riboflavin synthase, alpha
BFG52_RS12525	COG0456	acetyltransferase
BFG52_RS12535	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BFG52_RS12540	COG2885	chlorophyll binding
BFG52_RS12545	COG0204	Acyl-transferase
BFG52_RS12555	COG0850	regulation of cytokinetic process
BFG52_RS12565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BFG52_RS12580	COG1674	ftsk spoiiie
BFG52_RS12585	COG0492	ferredoxin-NADP+ reductase activity
BFG52_RS12590	COG0210	DNA helicase
BFG52_RS12595	COG0756	dUTP diphosphatase activity
BFG52_RS12600	COG2205	protein histidine kinase activity
BFG52_RS12605	COG0745	RESPONSE REGULATOR receiver
BFG52_RS12610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFG52_RS12610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFG52_RS12615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFG52_RS12625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BFG52_RS12640	COG3397	chitin binding
BFG52_RS12655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFG52_RS12670	COG1012	belongs to the aldehyde dehydrogenase family
BFG52_RS12675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFG52_RS12680	COG1012	belongs to the aldehyde dehydrogenase family
BFG52_RS12700	COG0531	amino acid
BFG52_RS12705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFG52_RS12720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFG52_RS12735	COG1607	acyl-coa hydrolase
BFG52_RS12750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFG52_RS12795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFG52_RS12825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFG52_RS12825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFG52_RS12840	COG0037	tRNA processing
BFG52_RS12870	COG0776	regulation of translation
BFG52_RS12875	COG0072	phenylalanine-tRNA ligase activity
BFG52_RS12905	COG0625	glutathione transferase activity
BFG52_RS12930	COG0318	PFAM AMP-dependent synthetase and ligase
BFG52_RS12935	COG3028	Belongs to the UPF0307 family
BFG52_RS12940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFG52_RS12960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BFG52_RS12965	COG0617	tRNA 3'-terminal CCA addition
BFG52_RS12970	COG1555	photosystem II stabilization
BFG52_RS12970	COG1596	polysaccharide export
BFG52_RS12975	COG3956	TIGRFAM MazG family protein
BFG52_RS12985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFG52_RS13005	COG2205	protein histidine kinase activity
BFG52_RS13005	COG5002	protein histidine kinase activity
BFG52_RS13005	COG0784	Response regulator, receiver
BFG52_RS13010	COG1024	Enoyl-CoA hydratase
BFG52_RS13015	COG2084	Dehydrogenase
BFG52_RS13020	COG3622	Belongs to the hyi family
BFG52_RS13030	COG0004	ammonium transporteR
BFG52_RS13070	COG2814	Major facilitator Superfamily
BFG52_RS13075	COG0531	amino acid
BFG52_RS13095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFG52_RS13100	COG1349	DNA-binding transcription factor activity
BFG52_RS13150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BFG52_RS13155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BFG52_RS13180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFG52_RS13190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFG52_RS13200	COG0028	Belongs to the TPP enzyme family
BFG52_RS13225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFG52_RS13230	COG1136	(ABC) transporter
BFG52_RS13230	COG0577	efflux transmembrane transporter activity
BFG52_RS13235	COG1538	Outer membrane efflux protein
BFG52_RS13250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BFG52_RS13255	COG1162	GTPase activity
BFG52_RS13265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFG52_RS13280	COG0285	dihydrofolate synthase activity
BFG52_RS13285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFG52_RS13300	COG2207	Transcriptional regulator
BFG52_RS13310	COG2153	protein acetylation
BFG52_RS13320	COG1272	protein, Hemolysin III
BFG52_RS13325	COG0477	Major facilitator Superfamily
BFG52_RS13330	COG1408	metallophosphoesterase
BFG52_RS13335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFG52_RS13345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFG52_RS13360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFG52_RS13365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BFG52_RS13370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BFG52_RS13380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BFG52_RS13385	COG0625	glutathione transferase activity
BFG52_RS13390	COG2969	positive regulation of protein catabolic process
BFG52_RS13440	COG2885	chlorophyll binding
BFG52_RS13475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BFG52_RS13495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFG52_RS13495	COG2169	Transcriptional regulator
BFG52_RS13500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFG52_RS13505	COG3781	membrane
BFG52_RS13510	COG0587	DNA-directed DNA polymerase activity
BFG52_RS13520	COG2350	Protein conserved in bacteria
BFG52_RS13540	COG1862	Preprotein translocase
BFG52_RS13575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFG52_RS13580	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS13620	COG2986	histidine ammonia-lyase
BFG52_RS13645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFG52_RS13650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFG52_RS13670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFG52_RS13690	COG1426	Protein conserved in bacteria
BFG52_RS13710	COG2975	iron-sulfur cluster assembly
BFG52_RS13735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BFG52_RS13760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BFG52_RS13765	COG0084	hydrolase, TatD family'
BFG52_RS13775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BFG52_RS13790	COG0793	Belongs to the peptidase S41A family
BFG52_RS13800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFG52_RS13805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFG52_RS13810	COG0857	belongs to the CobB CobQ family
BFG52_RS13810	COG0280	phosphate acetyltransferase
BFG52_RS13815	COG1051	belongs to the nudix hydrolase family
BFG52_RS13820	COG1696	Membrane protein involved in D-alanine export
BFG52_RS13835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BFG52_RS13835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BFG52_RS13850	COG0494	nUDIX hydrolase
BFG52_RS13860	COG0753	catalase activity
BFG52_RS13870	COG0546	phosphoglycolate phosphatase activity
BFG52_RS13875	COG0564	pseudouridine synthase activity
BFG52_RS13880	COG1530	ribonuclease E activity
BFG52_RS13885	COG0318	PFAM AMP-dependent synthetase and ligase
BFG52_RS13905	COG1983	PspC domain protein
BFG52_RS13975	COG0628	permease
BFG52_RS13985	COG1289	transmembrane transporter activity
BFG52_RS14005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFG52_RS14015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFG52_RS14035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BFG52_RS14035	COG2111	Na H antiporter
BFG52_RS14040	COG1006	Multisubunit Na H antiporter MnhC subunit
BFG52_RS14045	COG0651	ATP synthesis coupled electron transport
BFG52_RS14050	COG1863	multisubunit Na H antiporter MnhE subunit
BFG52_RS14055	COG2212	antiporter activity
BFG52_RS14060	COG1320	monovalent cation:proton antiporter activity
BFG52_RS14070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFG52_RS14075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFG52_RS14080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BFG52_RS14090	COG4774	siderophore transport
BFG52_RS14095	COG4716	Myosin-crossreactive antigen
BFG52_RS14105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFG52_RS14110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BFG52_RS14140	COG0765	amino acid transport
BFG52_RS14145	COG0765	amino acid transport
BFG52_RS14150	COG1126	abc transporter atp-binding protein
BFG52_RS14160	COG0741	lytic transglycosylase activity
BFG52_RS14195	COG1183	phosphatidylcholine synthase activity
BFG52_RS14200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BFG52_RS14215	COG0039	L-malate dehydrogenase activity
BFG52_RS14225	COG0739	heme binding
BFG52_RS14225	COG0741	lytic transglycosylase activity
BFG52_RS14225	COG1196	nuclear chromosome segregation
BFG52_RS14230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFG52_RS14235	COG1702	phosphate starvation-inducible protein PhoH
BFG52_RS14240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFG52_RS14280	COG1295	ribonuclease BN
BFG52_RS14310	COG0740	serine-type endopeptidase activity
BFG52_RS14320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFG52_RS14330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFG52_RS14330	COG2813	Specifically methylates the guanine in position
BFG52_RS14340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFG52_RS14365	COG2819	hydrolase of the alpha beta superfamily
BFG52_RS14370	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFG52_RS14375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFG52_RS14415	COG0788	formyltetrahydrofolate deformylase activity
BFG52_RS14440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFG52_RS14440	COG4651	solute:proton antiporter activity
BFG52_RS14450	COG0179	Fumarylacetoacetate (FAA) hydrolase
BFG52_RS14480	COG0557	exoribonuclease II activity
BFG52_RS14500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFG52_RS14540	COG2226	methyltransferase
BFG52_RS14545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFG52_RS14550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFG52_RS14555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFG52_RS14575	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BFG52_RS14585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFG52_RS14625	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BFG52_RS14630	COG0194	GDP metabolic process
BFG52_RS14635	COG1758	RNA polymerase activity
BFG52_RS14640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFG52_RS14650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFG52_RS14655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFG52_RS14685	COG1944	ATP diphosphatase activity
BFG52_RS14750	COG3409	Peptidoglycan-binding domain 1 protein
BFG52_RS14750	COG5632	N-Acetylmuramoyl-L-alanine amidase
BFG52_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
BFG52_RS14765	COG2207	Transcriptional regulator
BFG52_RS14765	COG3708	Transcriptional regulator
BFG52_RS14770	COG0697	spore germination
BFG52_RS14775	COG0629	single-stranded DNA binding
BFG52_RS14780	COG2814	Major facilitator Superfamily
BFG52_RS14785	COG0351	phosphomethylpyrimidine kinase
BFG52_RS14785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BFG52_RS14785	COG0352	thiamine-phosphate diphosphorylase activity
BFG52_RS14800	COG3188	usher protein
BFG52_RS14805	COG3121	Chaperone
BFG52_RS14825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFG52_RS14830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFG52_RS14835	COG3162	membrane
BFG52_RS14840	COG2205	protein histidine kinase activity
BFG52_RS14840	COG0784	Response regulator, receiver
BFG52_RS14855	COG0431	NADPH-dependent FMN reductase
BFG52_RS14860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFG52_RS14890	COG0009	L-threonylcarbamoyladenylate synthase
BFG52_RS14895	COG0758	DNA mediated transformation
BFG52_RS14915	COG0697	spore germination
BFG52_RS14920	COG1309	transcriptional regulator
BFG52_RS14925	COG2814	Major facilitator Superfamily
BFG52_RS14930	COG0386	Belongs to the glutathione peroxidase family
BFG52_RS14970	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFG52_RS14970	COG1024	Enoyl-CoA hydratase
BFG52_RS14975	COG0183	Belongs to the thiolase family
BFG52_RS14995	COG2995	paraquat-inducible protein a
BFG52_RS15000	COG2995	paraquat-inducible protein a
BFG52_RS15005	COG3008	intermembrane lipid transfer
BFG52_RS15005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFG52_RS15020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFG52_RS15025	COG0085	RNA polymerase activity
BFG52_RS15040	COG0081	regulation of translation
BFG52_RS15055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFG52_RS15145	COG0181	hydroxymethylbilane synthase activity
BFG52_RS15175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BFG52_RS15185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BFG52_RS15190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFG52_RS15195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFG52_RS15200	COG0772	Belongs to the SEDS family
BFG52_RS15210	COG4667	esterase of the alpha-beta hydrolase superfamily
BFG52_RS15230	COG4974	Belongs to the 'phage' integrase family
BFG52_RS15235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFG52_RS15250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFG52_RS15255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BFG52_RS15320	COG3293	Transposase
BFG52_RS15370	COG0326	Molecular chaperone. Has ATPase activity
BFG52_RS15395	COG0277	FAD linked oxidase domain protein
BFG52_RS15405	COG2186	Transcriptional regulator
BFG52_RS15410	COG1620	l-lactate permease
BFG52_RS15430	COG0842	Transport permease protein
BFG52_RS15435	COG0842	Transport permease protein
BFG52_RS15435	COG1129	ABC transporter
BFG52_RS15440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFG52_RS15505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BFG52_RS15510	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BFG52_RS15515	COG1113	amino acid transport
BFG52_RS15525	COG1686	Belongs to the peptidase S11 family
BFG52_RS15530	COG2197	response regulator
BFG52_RS15535	COG0793	Belongs to the peptidase S41A family
BFG52_RS15540	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BFG52_RS15545	COG0795	lipopolysaccharide-transporting ATPase activity
BFG52_RS15550	COG0795	lipopolysaccharide-transporting ATPase activity
BFG52_RS15570	COG0586	Pfam SNARE associated Golgi protein
BFG52_RS15585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFG52_RS15585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFG52_RS15590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFG52_RS15595	COG0004	ammonium transporteR
BFG52_RS15600	COG0347	Belongs to the P(II) protein family
BFG52_RS15615	COG0583	DNA-binding transcription factor activity
BFG52_RS15625	COG2814	Major facilitator Superfamily
BFG52_RS15630	COG0697	spore germination
BFG52_RS15635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFG52_RS15655	COG1519	Transferase
BFG52_RS15665	COG0668	transmembrane transport
BFG52_RS15670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFG52_RS15680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BFG52_RS15705	COG2119	membrane
BFG52_RS15745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BFG52_RS15780	COG0708	Exodeoxyribonuclease III
BFG52_RS15795	COG0625	glutathione transferase activity
BFG52_RS15820	COG1247	-acetyltransferase
BFG52_RS15835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFG52_RS15840	COG1335	isochorismatase
BFG52_RS15845	COG0385	Bile acid
BFG52_RS15880	COG0560	Phosphoserine phosphatase
BFG52_RS15880	COG3830	Belongs to the UPF0237 family
BFG52_RS15900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BFG52_RS15915	COG0318	PFAM AMP-dependent synthetase and ligase
BFG52_RS15925	COG0477	Major facilitator Superfamily
BFG52_RS15930	COG2860	membrane
BFG52_RS15935	COG3012	SEC-C Motif Domain Protein
BFG52_RS15940	COG1253	flavin adenine dinucleotide binding
BFG52_RS15950	COG2814	Major facilitator Superfamily
BFG52_RS15960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFG52_RS15975	COG1280	lysine exporter protein (LysE YggA)
BFG52_RS15990	COG0789	Transcriptional regulator
BFG52_RS15995	COG2814	Major facilitator Superfamily
BFG52_RS16000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFG52_RS16010	COG2951	lytic endotransglycosylase activity
BFG52_RS16030	COG0534	Mate efflux family protein
BFG52_RS16040	COG0436	Aminotransferase
BFG52_RS16045	COG2733	membrane
BFG52_RS16055	COG2918	glutathione biosynthetic process
BFG52_RS16070	COG3150	esterase
BFG52_RS16080	COG1448	Aminotransferase
BFG52_RS16090	COG1280	lysine exporter protein (LysE YggA)
BFG52_RS16095	COG1301	dicarboxylic acid transport
BFG52_RS16100	COG3121	Chaperone
BFG52_RS16110	COG3188	usher protein
BFG52_RS16115	COG3121	Chaperone
BFG52_RS16125	COG0783	Belongs to the Dps family
BFG52_RS16140	COG1595	DNA-templated transcription, initiation
BFG52_RS16150	COG4774	siderophore transport
BFG52_RS16175	COG0235	Class ii aldolase
BFG52_RS16180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFG52_RS16210	COG1595	DNA-templated transcription, initiation
BFG52_RS16220	COG4773	Receptor
BFG52_RS16230	COG0318	PFAM AMP-dependent synthetase and ligase
BFG52_RS16235	COG1309	transcriptional regulator
BFG52_RS16240	COG1960	acyl-CoA dehydrogenase activity
BFG52_RS16245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFG52_RS16250	COG1024	Enoyl-CoA hydratase
BFG52_RS16265	COG1595	DNA-templated transcription, initiation
BFG52_RS16280	COG3135	benzoate transporter
BFG52_RS16285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFG52_RS16295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFG52_RS16300	COG0505	Belongs to the CarA family
BFG52_RS16330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BFG52_RS16360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFG52_RS16370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BFG52_RS16375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BFG52_RS16430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BFG52_RS16440	COG0861	Integral membrane protein TerC family
BFG52_RS16455	COG0402	S-adenosylhomocysteine deaminase activity
BFG52_RS16470	COG1309	transcriptional regulator
BFG52_RS16475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFG52_RS16480	COG1230	cation diffusion facilitator family transporter
BFG52_RS16495	COG4771	TonB-dependent receptor
BFG52_RS16505	COG0706	membrane insertase activity
BFG52_RS16510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BFG52_RS16515	COG0594	ribonuclease P activity
BFG52_RS16575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFG52_RS16585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BFG52_RS16615	COG3209	COG3209 Rhs family protein
BFG52_RS16715	COG3209	COG3209 Rhs family protein