locus-tag	class	description
FOB21_RS00025	COG0281	malic enzyme
FOB21_RS00030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB21_RS00045	COG0583	DNA-binding transcription factor activity
FOB21_RS00075	COG3657	addiction module killer protein
FOB21_RS00080	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_RS00085	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOB21_RS00090	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB21_RS00100	COG0583	DNA-binding transcription factor activity
FOB21_RS00105	COG3077	Addiction module antitoxin, RelB DinJ family
FOB21_RS00135	COG2801	Transposase and inactivated derivatives
FOB21_RS00150	COG3293	Transposase
FOB21_RS00185	COG3293	Transposase
FOB21_RS00195	COG1192	Involved in chromosome partitioning
FOB21_RS00215	COG3385	transposase activity
FOB21_RS00230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB21_RS00235	COG4774	siderophore transport
FOB21_RS00255	COG1454	alcohol dehydrogenase
FOB21_RS00280	COG4773	Receptor
FOB21_RS00305	COG2267	carboxylic ester hydrolase activity
FOB21_RS00305	COG2226	methyltransferase
FOB21_RS00320	COG4106	trans-aconitate 2-methyltransferase activity
FOB21_RS00330	COG0642	Histidine kinase
FOB21_RS00345	COG2186	Transcriptional regulator
FOB21_RS00355	COG4628	conserved protein (DUF2132)
FOB21_RS00380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB21_RS00385	COG3550	peptidyl-serine autophosphorylation
FOB21_RS00460	COG1203	CRISPR-associated helicase, Cas3
FOB21_RS00495	COG3540	Alkaline phosphatase
FOB21_RS00510	COG3293	Transposase
FOB21_RS00520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB21_RS00520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB21_RS00525	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB21_RS00530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB21_RS00530	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB21_RS00530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB21_RS00555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB21_RS00555	COG0475	glutathione-regulated potassium exporter activity
FOB21_RS00575	COG1309	transcriptional regulator
FOB21_RS00580	COG0604	alcohol dehydrogenase
FOB21_RS00605	COG2801	Transposase and inactivated derivatives
FOB21_RS00665	COG0730	response to heat
FOB21_RS00670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB21_RS00675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB21_RS00705	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB21_RS00735	COG3293	Transposase
FOB21_RS00740	COG3539	Fimbrial protein
FOB21_RS00790	COG0604	alcohol dehydrogenase
FOB21_RS00790	COG3321	synthase
FOB21_RS00795	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOB21_RS00800	COG0583	DNA-binding transcription factor activity
FOB21_RS00805	COG4221	oxidoreductase activity
FOB21_RS00830	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_RS00840	COG4372	Transposase
FOB21_RS00855	COG0640	Transcriptional regulator
FOB21_RS00885	COG2132	Multicopper oxidase
FOB21_RS00890	COG2801	Transposase and inactivated derivatives
FOB21_RS00935	COG2205	protein histidine kinase activity
FOB21_RS00940	COG3174	membrane
FOB21_RS00945	COG2217	Heavy metal translocating P-type atpase
FOB21_RS01005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_RS01090	COG0542	response to heat
FOB21_RS01120	COG0372	Belongs to the citrate synthase family
FOB21_RS01160	COG0753	catalase activity
FOB21_RS01165	COG2814	Major facilitator Superfamily
FOB21_RS01185	COG0439	Biotin carboxylase
FOB21_RS01195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB21_RS01200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB21_RS01235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB21_RS01275	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_RS01290	COG0596	Alpha beta hydrolase
FOB21_RS01305	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_RS01315	COG2801	Transposase and inactivated derivatives
FOB21_RS01320	COG0300	oxidoreductase activity
FOB21_RS01350	COG0642	Histidine kinase
FOB21_RS01355	COG0745	RESPONSE REGULATOR receiver
FOB21_RS01360	COG2194	sulfuric ester hydrolase activity
FOB21_RS01390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB21_RS01395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB21_RS01415	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_RS01425	COG1024	Enoyl-CoA hydratase
FOB21_RS01430	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS01435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB21_RS01450	COG0583	DNA-binding transcription factor activity
FOB21_RS01470	COG2814	Major facilitator Superfamily
FOB21_RS01480	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_RS01495	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS01505	COG1024	Enoyl-CoA hydratase
FOB21_RS01510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB21_RS01515	COG0235	Class ii aldolase
FOB21_RS01525	COG0183	Belongs to the thiolase family
FOB21_RS01530	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_RS01535	COG1024	Enoyl-CoA hydratase
FOB21_RS01540	COG2814	Major facilitator Superfamily
FOB21_RS01550	COG2814	Major facilitator Superfamily
FOB21_RS01555	COG5001	Diguanylate cyclase
FOB21_RS01560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB21_RS01565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOB21_RS01570	COG2814	Major facilitator Superfamily
FOB21_RS01575	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS01580	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS01590	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOB21_RS01590	COG0644	oxidoreductase
FOB21_RS01595	COG1944	ATP diphosphatase activity
FOB21_RS01615	COG1309	transcriptional regulator
FOB21_RS01620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB21_RS01635	COG0583	DNA-binding transcription factor activity
FOB21_RS01645	COG0515	serine threonine protein kinase
FOB21_RS01650	COG2116	formate transmembrane transporter activity
FOB21_RS01655	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FOB21_RS01675	COG3293	Transposase
FOB21_RS01680	COG2223	nitrite transmembrane transporter activity
FOB21_RS01685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOB21_RS01690	COG4149	molybdate abc transporter
FOB21_RS01695	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB21_RS01700	COG0303	'Molybdopterin
FOB21_RS01705	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB21_RS01705	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB21_RS01710	COG0314	molybdopterin synthase activity
FOB21_RS01720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOB21_RS01730	COG0243	molybdopterin cofactor binding
FOB21_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_RS01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_RS01750	COG1116	anion transmembrane transporter activity
FOB21_RS01750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB21_RS01755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB21_RS01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB21_RS01790	COG0864	Transcriptional regulator
FOB21_RS01840	COG0439	Biotin carboxylase
FOB21_RS01865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB21_RS01880	COG1017	nitric oxide dioxygenase activity
FOB21_RS01880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB21_RS01885	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_RS01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB21_RS01900	COG2814	Major facilitator Superfamily
FOB21_RS01905	COG0583	DNA-binding transcription factor activity
FOB21_RS01910	COG4948	Mandelate Racemase Muconate Lactonizing
FOB21_RS01915	COG4829	muconolactone delta-isomerase
FOB21_RS01925	COG4638	Rieske (2fe-2S)
FOB21_RS01930	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FOB21_RS01935	COG0543	2 iron, 2 sulfur cluster binding
FOB21_RS01935	COG0633	Ferredoxin
FOB21_RS01940	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_RS01945	COG3135	benzoate transporter
FOB21_RS01950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOB21_RS01955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB21_RS01960	COG0183	Belongs to the thiolase family
FOB21_RS01965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_RS01990	COG0183	Belongs to the thiolase family
FOB21_RS01995	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS02010	COG0789	Transcriptional regulator
FOB21_RS02020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB21_RS02025	COG0640	Transcriptional regulator
FOB21_RS02045	COG3122	Protein conserved in bacteria
FOB21_RS02050	COG0668	transmembrane transport
FOB21_RS02055	COG1132	(ABC) transporter
FOB21_RS02065	COG0509	glycine decarboxylation via glycine cleavage system
FOB21_RS02070	COG2814	Major facilitator Superfamily
FOB21_RS02085	COG2801	Transposase and inactivated derivatives
FOB21_RS02090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB21_RS02100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOB21_RS02105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB21_RS02160	COG1525	nuclease
FOB21_RS02170	COG1294	oxidase, subunit
FOB21_RS02175	COG1271	oxidase subunit
FOB21_RS02190	COG2169	Transcriptional regulator
FOB21_RS02195	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS02200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB21_RS02205	COG2207	Transcriptional regulator
FOB21_RS02210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB21_RS02215	COG0730	response to heat
FOB21_RS02220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB21_RS02285	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS02290	COG0456	acetyltransferase
FOB21_RS02325	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB21_RS02340	COG0552	protein localization to endoplasmic reticulum
FOB21_RS02345	COG0612	Peptidase, M16
FOB21_RS02375	COG0517	IMP dehydrogenase activity
FOB21_RS02380	COG0133	tryptophan synthase activity
FOB21_RS02390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB21_RS02410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB21_RS02440	COG0537	adenosine 5'-monophosphoramidase activity
FOB21_RS02460	COG1294	oxidase, subunit
FOB21_RS02465	COG4890	Cyd operon protein YbgT
FOB21_RS02475	COG0772	Belongs to the SEDS family
FOB21_RS02490	COG0148	phosphopyruvate hydratase activity
FOB21_RS02525	COG1902	pentaerythritol trinitrate reductase activity
FOB21_RS02525	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB21_RS02540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB21_RS02545	COG0583	DNA-binding transcription factor activity
FOB21_RS02610	COG1570	exodeoxyribonuclease VII activity
FOB21_RS02620	COG3385	transposase activity
FOB21_RS02655	COG0729	surface antigen
FOB21_RS02660	COG0477	Major facilitator Superfamily
FOB21_RS02675	COG3293	Transposase
FOB21_RS02705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB21_RS02715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB21_RS02720	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS02740	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB21_RS02745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB21_RS02760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_RS02785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB21_RS02790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB21_RS02795	COG1845	cytochrome c oxidase, subunit III
FOB21_RS02800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB21_RS02810	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB21_RS02825	COG0305	Participates in initiation and elongation during chromosome replication
FOB21_RS02830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB21_RS02845	COG1305	Transglutaminase-like
FOB21_RS02855	COG2308	Evidence 4 Homologs of previously reported genes of
FOB21_RS02865	COG0069	glutamate synthase activity
FOB21_RS02885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB21_RS02890	COG1454	alcohol dehydrogenase
FOB21_RS02895	COG0824	Thioesterase
FOB21_RS02900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB21_RS02925	COG0183	Belongs to the thiolase family
FOB21_RS02930	COG3385	transposase activity
FOB21_RS02945	COG0583	DNA-binding transcription factor activity
FOB21_RS02950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB21_RS02960	COG3135	benzoate transporter
FOB21_RS02975	COG0589	response to stress
FOB21_RS02980	COG0589	response to stress
FOB21_RS02990	COG0308	aminopeptidase N
FOB21_RS03010	COG1253	flavin adenine dinucleotide binding
FOB21_RS03030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB21_RS03035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB21_RS03050	COG2431	L-lysine efflux transmembrane transporter activity
FOB21_RS03065	COG0776	regulation of translation
FOB21_RS03095	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB21_RS03125	COG1309	transcriptional regulator
FOB21_RS03130	COG0084	hydrolase, TatD family'
FOB21_RS03150	COG1663	tetraacyldisaccharide 4'-kinase activity
FOB21_RS03155	COG1132	(ABC) transporter
FOB21_RS03165	COG0811	peptide transport
FOB21_RS03170	COG1475	DNA binding
FOB21_RS03175	COG1192	Involved in chromosome partitioning
FOB21_RS03185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOB21_RS03190	COG3178	'Phosphotransferase
FOB21_RS03200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB21_RS03205	COG1923	regulation of RNA biosynthetic process
FOB21_RS03215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB21_RS03220	COG0802	atpase or kinase
FOB21_RS03260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_RS03280	COG1643	Atp-dependent helicase
FOB21_RS03305	COG3634	alkyl hydroperoxide reductase activity
FOB21_RS03340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB21_RS03340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB21_RS03420	COG0656	L-ascorbic acid biosynthetic process
FOB21_RS03475	COG4372	Transposase
FOB21_RS03510	COG4372	Transposase
FOB21_RS03580	COG2233	PERMEase
FOB21_RS03600	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FOB21_RS03630	COG0583	DNA-binding transcription factor activity
FOB21_RS03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB21_RS03640	COG4266	Belongs to the allantoicase family
FOB21_RS03650	COG3385	transposase activity
FOB21_RS03660	COG2233	PERMEase
FOB21_RS03665	COG2351	hydroxyisourate hydrolase activity
FOB21_RS03685	COG0804	urea catabolic process
FOB21_RS03700	COG0831	urea catabolic process
FOB21_RS03705	COG0829	nickel cation binding
FOB21_RS03720	COG0830	nickel cation binding
FOB21_RS03755	COG4372	Transposase
FOB21_RS03775	COG4372	Transposase
FOB21_RS03800	COG0204	Acyl-transferase
FOB21_RS03825	COG0012	GTP binding
FOB21_RS03830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB21_RS03840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB21_RS03860	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOB21_RS03870	COG0386	Belongs to the glutathione peroxidase family
FOB21_RS03875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB21_RS03880	COG0436	Aminotransferase
FOB21_RS03905	COG2351	hydroxyisourate hydrolase activity
FOB21_RS03930	COG1686	Belongs to the peptidase S11 family
FOB21_RS03935	COG1252	NADH dehydrogenase
FOB21_RS03955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB21_RS03970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB21_RS03985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB21_RS03990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB21_RS03995	COG0527	aspartate kinase activity
FOB21_RS04005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB21_RS04025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB21_RS04030	COG2252	PERMEase
FOB21_RS04055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB21_RS04060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB21_RS04070	COG0693	protein deglycase activity
FOB21_RS04075	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS04080	COG1301	dicarboxylic acid transport
FOB21_RS04090	COG3139	Protein of unknown function (DUF1315)
FOB21_RS04095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB21_RS04100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB21_RS04110	COG0494	nUDIX hydrolase
FOB21_RS04120	COG0642	Histidine kinase
FOB21_RS04135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB21_RS04145	COG1720	tRNA m6t6A37 methyltransferase activity
FOB21_RS04175	COG0826	peptidase U32
FOB21_RS04180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB21_RS04185	COG3634	alkyl hydroperoxide reductase activity
FOB21_RS04205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB21_RS04250	COG3328	transposase activity
FOB21_RS04265	COG3706	GGDEF domain
FOB21_RS04410	COG2369	cell adhesion
FOB21_RS04415	COG3567	Phage-associated protein, HI1409 family
FOB21_RS04420	COG5410	chromosome segregation
FOB21_RS04570	COG1131	(ABC) transporter
FOB21_RS04575	COG0842	Transport permease protein
FOB21_RS04590	COG2951	lytic endotransglycosylase activity
FOB21_RS04615	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB21_RS04625	COG0436	Aminotransferase
FOB21_RS04630	COG0534	Mate efflux family protein
FOB21_RS04655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB21_RS04670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB21_RS04675	COG0571	ribonuclease III activity
FOB21_RS04700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB21_RS04730	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_RS04735	COG4372	Transposase
FOB21_RS04755	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_RS04790	COG4372	Transposase
FOB21_RS04805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB21_RS04815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB21_RS04820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB21_RS04835	COG4208	sulfate ABC transporter
FOB21_RS04840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB21_RS04845	COG0583	DNA-binding transcription factor activity
FOB21_RS04865	COG0602	queuosine metabolic process
FOB21_RS04870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOB21_RS04880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB21_RS04885	COG2353	YceI-like domain
FOB21_RS04895	COG0583	DNA-binding transcription factor activity
FOB21_RS04900	COG1056	cytidyltransferase-related domain
FOB21_RS04900	COG1051	belongs to the nudix hydrolase family
FOB21_RS04910	COG0778	Nitroreductase
FOB21_RS04915	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FOB21_RS04940	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB21_RS04940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB21_RS04960	COG2255	four-way junction helicase activity
FOB21_RS04975	COG1473	amidohydrolase
FOB21_RS04980	COG0824	Thioesterase
FOB21_RS05000	COG0823	Involved in the tonB-independent uptake of proteins
FOB21_RS05020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB21_RS05040	COG3385	transposase activity
FOB21_RS05065	COG2267	carboxylic ester hydrolase activity
FOB21_RS05070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB21_RS05075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB21_RS05080	COG0628	permease
FOB21_RS05085	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB21_RS05105	COG2333	competence protein COMEC
FOB21_RS05105	COG0658	competence protein
FOB21_RS05110	COG1136	(ABC) transporter
FOB21_RS05130	COG1671	Belongs to the UPF0178 family
FOB21_RS05155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_RS05175	COG3385	transposase activity
FOB21_RS05200	COG1280	lysine exporter protein (LysE YggA)
FOB21_RS05205	COG1522	sequence-specific DNA binding
FOB21_RS05215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB21_RS05220	COG2267	carboxylic ester hydrolase activity
FOB21_RS05230	COG0019	diaminopimelate decarboxylase activity
FOB21_RS05240	COG1113	amino acid transport
FOB21_RS05245	COG1115	amino acid carrier protein
FOB21_RS05285	COG3385	transposase activity
FOB21_RS05290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOB21_RS05295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB21_RS05300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB21_RS05305	COG5001	Diguanylate cyclase
FOB21_RS05305	COG1716	ATPase activity
FOB21_RS05320	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOB21_RS05340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB21_RS05355	COG0037	tRNA processing
FOB21_RS05360	COG0739	heme binding
FOB21_RS05360	COG0741	lytic transglycosylase activity
FOB21_RS05360	COG1196	nuclear chromosome segregation
FOB21_RS05365	COG0501	Belongs to the peptidase M48B family
FOB21_RS05375	COG2239	Acts as a magnesium transporter
FOB21_RS05400	COG1253	flavin adenine dinucleotide binding
FOB21_RS05435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB21_RS05445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB21_RS05475	COG0505	Belongs to the CarA family
FOB21_RS05480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB21_RS05490	COG1309	transcriptional regulator
FOB21_RS05495	COG0251	oxidation-reduction process
FOB21_RS05500	COG0110	maltose O-acetyltransferase activity
FOB21_RS05510	COG3293	Transposase
FOB21_RS05530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB21_RS05555	COG0564	pseudouridine synthase activity
FOB21_RS05565	COG0358	DNA primase activity
FOB21_RS05570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB21_RS05580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOB21_RS05610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB21_RS05615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB21_RS05640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB21_RS05665	COG0586	Pfam SNARE associated Golgi protein
FOB21_RS05695	COG0321	lipoyl(octanoyl) transferase activity
FOB21_RS05710	COG0531	amino acid
FOB21_RS05720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB21_RS05725	COG1648	precorrin-2 dehydrogenase activity
FOB21_RS05725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB21_RS05730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB21_RS05740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB21_RS05750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB21_RS05765	COG0671	phosphoesterase, PA-phosphatase related
FOB21_RS05770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_RS05785	COG0393	Putative heavy-metal-binding
FOB21_RS05790	COG0393	Putative heavy-metal-binding
FOB21_RS05820	COG2203	Gaf domain
FOB21_RS05820	COG4251	negative regulation of phosphorylation
FOB21_RS05820	COG3706	GGDEF domain
FOB21_RS05820	COG5001	Diguanylate cyclase
FOB21_RS05835	COG4681	YaeQ
FOB21_RS05840	COG0523	cobalamin synthesis protein
FOB21_RS05875	COG2814	Major facilitator Superfamily
FOB21_RS05885	COG1607	acyl-coa hydrolase
FOB21_RS05890	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB21_RS05895	COG2059	Chromate
FOB21_RS05900	COG1115	amino acid carrier protein
FOB21_RS05905	COG0786	glutamate:sodium symporter activity
FOB21_RS05920	COG1289	transmembrane transporter activity
FOB21_RS05930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB21_RS05990	COG2832	Protein of unknown function (DUF454)
FOB21_RS06020	COG0840	transmembrane signaling receptor activity
FOB21_RS06060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_RS06105	COG0489	protein tyrosine kinase activity
FOB21_RS06120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB21_RS06120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB21_RS06135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB21_RS06140	COG0004	ammonium transporteR
FOB21_RS06165	COG2081	HI0933 family
FOB21_RS06175	COG0668	transmembrane transport
FOB21_RS06185	COG4302	ethanolamine ammonia-lyase activity
FOB21_RS06195	COG0531	amino acid
FOB21_RS06215	COG0583	DNA-binding transcription factor activity
FOB21_RS06220	COG1278	Cold shock
FOB21_RS06245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB21_RS06250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB21_RS06255	COG0713	ATP synthesis coupled electron transport
FOB21_RS06265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB21_RS06280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOB21_RS06300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB21_RS06310	COG2205	protein histidine kinase activity
FOB21_RS06315	COG0745	RESPONSE REGULATOR receiver
FOB21_RS06320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB21_RS06320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB21_RS06325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB21_RS06330	COG3152	Membrane
FOB21_RS06335	COG2314	TM2 domain
FOB21_RS06345	COG4772	TonB-dependent receptor
FOB21_RS06365	COG3152	Membrane
FOB21_RS06380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB21_RS06380	COG0352	thiamine-phosphate diphosphorylase activity
FOB21_RS06380	COG0351	phosphomethylpyrimidine kinase
FOB21_RS06415	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB21_RS06440	COG0564	pseudouridine synthase activity
FOB21_RS06485	COG0354	folic acid binding
FOB21_RS06500	COG3385	transposase activity
FOB21_RS06510	COG1902	pentaerythritol trinitrate reductase activity
FOB21_RS06535	COG1217	gtp-binding protein TYPA
FOB21_RS06540	COG2233	PERMEase
FOB21_RS06550	COG0833	amino acid
FOB21_RS06570	COG0183	Belongs to the thiolase family
FOB21_RS06590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_RS06595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB21_RS06600	COG2207	Transcriptional regulator
FOB21_RS06605	COG0183	Belongs to the thiolase family
FOB21_RS06610	COG1024	Enoyl-CoA hydratase
FOB21_RS06610	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_RS06630	COG1272	protein, Hemolysin III
FOB21_RS06635	COG0477	Major facilitator Superfamily
FOB21_RS06645	COG1408	metallophosphoesterase
FOB21_RS06650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB21_RS06665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB21_RS06715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB21_RS06720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB21_RS06725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB21_RS06730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB21_RS06735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB21_RS06740	COG0625	glutathione transferase activity
FOB21_RS06745	COG2969	positive regulation of protein catabolic process
FOB21_RS06800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOB21_RS06805	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOB21_RS06815	COG0653	protein targeting
FOB21_RS06820	COG0450	alkyl hydroperoxide reductase
FOB21_RS06835	COG0285	dihydrofolate synthase activity
FOB21_RS06895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB21_RS06905	COG1704	LemA family
FOB21_RS06920	COG1862	Preprotein translocase
FOB21_RS06940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB21_RS06955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB21_RS06970	COG2084	Dehydrogenase
FOB21_RS06975	COG3622	Belongs to the hyi family
FOB21_RS07000	COG2814	Major facilitator Superfamily
FOB21_RS07010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB21_RS07020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB21_RS07025	COG2003	Belongs to the UPF0758 family
FOB21_RS07030	COG3781	membrane
FOB21_RS07045	COG2350	Protein conserved in bacteria
FOB21_RS07080	COG1607	acyl-coa hydrolase
FOB21_RS07140	COG1183	phosphatidylcholine synthase activity
FOB21_RS07145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB21_RS07175	COG3385	transposase activity
FOB21_RS07190	COG1196	nuclear chromosome segregation
FOB21_RS07190	COG0739	heme binding
FOB21_RS07190	COG0741	lytic transglycosylase activity
FOB21_RS07195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB21_RS07200	COG1702	phosphate starvation-inducible protein PhoH
FOB21_RS07300	COG1295	ribonuclease BN
FOB21_RS07320	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB21_RS07360	COG0557	exoribonuclease II activity
FOB21_RS07370	COG0339	signal peptide processing
FOB21_RS07375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOB21_RS07385	COG0697	spore germination
FOB21_RS07410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB21_RS07415	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS07420	COG2072	flavoprotein involved in K transport
FOB21_RS07425	COG0203	ribosomal protein L17
FOB21_RS07430	COG0202	RNA polymerase activity
FOB21_RS07435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB21_RS07445	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB21_RS07470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB21_RS07480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB21_RS07485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB21_RS07535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB21_RS07545	COG0089	rRNA binding
FOB21_RS07550	COG0088	Forms part of the polypeptide exit tunnel
FOB21_RS07570	COG0626	cystathionine gamma-synthase activity
FOB21_RS07575	COG0433	COG0433 Predicted ATPase
FOB21_RS07580	COG1017	nitric oxide dioxygenase activity
FOB21_RS07580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB21_RS07585	COG1959	2 iron, 2 sulfur cluster binding
FOB21_RS07595	COG1301	dicarboxylic acid transport
FOB21_RS07600	COG1946	Acyl-CoA thioesterase
FOB21_RS07605	COG2937	Belongs to the GPAT DAPAT family
FOB21_RS07615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB21_RS07620	COG1040	competence protein
FOB21_RS07625	COG0494	nUDIX hydrolase
FOB21_RS07635	COG0598	Magnesium transport protein CorA
FOB21_RS07655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB21_RS07660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB21_RS07665	COG1127	ABC transporter
FOB21_RS07670	COG0513	Belongs to the DEAD box helicase family
FOB21_RS07690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB21_RS07710	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS07715	COG1278	Cold shock
FOB21_RS07725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB21_RS07735	COG0534	Mate efflux family protein
FOB21_RS07745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB21_RS07750	COG0254	rRNA binding
FOB21_RS07755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB21_RS07790	COG0628	permease
FOB21_RS07800	COG1289	transmembrane transporter activity
FOB21_RS07805	COG2814	Major facilitator Superfamily
FOB21_RS07825	COG0277	FAD linked oxidase domain protein
FOB21_RS07830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB21_RS07880	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB21_RS07885	COG5380	lipid catabolic process
FOB21_RS07890	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB21_RS07895	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB21_RS07910	COG0335	large ribosomal subunit rRNA binding
FOB21_RS07920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB21_RS07925	COG0228	four-way junction DNA binding
FOB21_RS07975	COG0194	GDP metabolic process
FOB21_RS07980	COG1758	RNA polymerase activity
FOB21_RS07985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB21_RS08005	COG3307	-O-antigen
FOB21_RS08030	COG1704	LemA family
FOB21_RS08035	COG0493	'glutamate synthase
FOB21_RS08040	COG0070	glutamate synthase
FOB21_RS08040	COG0069	glutamate synthase activity
FOB21_RS08040	COG0067	glutamate synthase
FOB21_RS08095	COG2226	methyltransferase
FOB21_RS08105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB21_RS08110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB21_RS08130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB21_RS08150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB21_RS08170	COG0488	(ABC) transporter
FOB21_RS08180	COG4221	oxidoreductase activity
FOB21_RS08185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB21_RS08200	COG2111	Na H antiporter
FOB21_RS08200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB21_RS08205	COG1006	Multisubunit Na H antiporter MnhC subunit
FOB21_RS08210	COG0651	ATP synthesis coupled electron transport
FOB21_RS08215	COG1863	multisubunit Na H antiporter MnhE subunit
FOB21_RS08220	COG2212	antiporter activity
FOB21_RS08225	COG1320	monovalent cation:proton antiporter activity
FOB21_RS08235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB21_RS08245	COG0195	Participates in both transcription termination and antitermination
FOB21_RS08250	COG0779	Required for maturation of 30S ribosomal subunits
FOB21_RS08305	COG0237	dephospho-CoA kinase activity
FOB21_RS08315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB21_RS08320	COG3123	guanosine phosphorylase activity
FOB21_RS08325	COG0497	DNA recombination
FOB21_RS08335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB21_RS08345	COG1132	(ABC) transporter
FOB21_RS08375	COG0494	nUDIX hydrolase
FOB21_RS08385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB21_RS08390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB21_RS08400	COG0772	Belongs to the SEDS family
FOB21_RS08425	COG4974	Belongs to the 'phage' integrase family
FOB21_RS08430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_RS08440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB21_RS08445	COG1686	Belongs to the peptidase S11 family
FOB21_RS08450	COG2197	response regulator
FOB21_RS08465	COG0793	Belongs to the peptidase S41A family
FOB21_RS08465	COG3409	Peptidoglycan-binding domain 1 protein
FOB21_RS08470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOB21_RS08475	COG0795	lipopolysaccharide-transporting ATPase activity
FOB21_RS08480	COG0795	lipopolysaccharide-transporting ATPase activity
FOB21_RS08500	COG0586	Pfam SNARE associated Golgi protein
FOB21_RS08515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB21_RS08515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB21_RS08525	COG0004	ammonium transporteR
FOB21_RS08530	COG0347	Belongs to the P(II) protein family
FOB21_RS08540	COG0606	chelatase, subunit chli
FOB21_RS08555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB21_RS08570	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_RS08580	COG0477	Major facilitator Superfamily
FOB21_RS08585	COG2860	membrane
FOB21_RS08595	COG1253	flavin adenine dinucleotide binding
FOB21_RS08630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB21_RS08635	COG0477	Major facilitator Superfamily
FOB21_RS08655	COG2814	Major facilitator Superfamily
FOB21_RS08705	COG0758	DNA mediated transformation
FOB21_RS08715	COG0697	spore germination
FOB21_RS08720	COG0386	Belongs to the glutathione peroxidase family
FOB21_RS08735	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_RS08750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB21_RS08800	COG1121	(ABC) transporter
FOB21_RS08805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB21_RS08815	COG2837	iron assimilation
FOB21_RS08830	COG0436	Aminotransferase
FOB21_RS08835	COG0534	Mate efflux family protein
FOB21_RS08860	COG0625	glutathione transferase activity
FOB21_RS08870	COG3706	GGDEF domain
FOB21_RS08875	COG3706	GGDEF domain
FOB21_RS08880	COG1715	Restriction endonuclease
FOB21_RS08885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB21_RS08885	COG0519	Catalyzes the synthesis of GMP from XMP
FOB21_RS08890	COG0586	Pfam SNARE associated Golgi protein
FOB21_RS08905	COG1192	Involved in chromosome partitioning
FOB21_RS08915	COG0271	Belongs to the BolA IbaG family
FOB21_RS08950	COG3756	Protein conserved in bacteria
FOB21_RS09030	COG1538	Outer membrane efflux protein
FOB21_RS09350	COG0281	malic enzyme
FOB21_RS09370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOB21_RS09380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB21_RS09385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB21_RS09395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB21_RS09400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB21_RS09410	COG4372	Transposase
FOB21_RS09435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB21_RS09450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB21_RS09465	COG0297	glycogen (starch) synthase activity
FOB21_RS09470	COG0438	transferase activity, transferring glycosyl groups
FOB21_RS09475	COG0438	transferase activity, transferring glycosyl groups
FOB21_RS09495	COG1051	belongs to the nudix hydrolase family
FOB21_RS09505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB21_RS09525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB21_RS09535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB21_RS09545	COG0438	transferase activity, transferring glycosyl groups
FOB21_RS09550	COG0438	transferase activity, transferring glycosyl groups
FOB21_RS09555	COG0438	transferase activity, transferring glycosyl groups
FOB21_RS09580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB21_RS09620	COG1194	a g-specific adenine glycosylase
FOB21_RS09625	COG0739	heme binding
FOB21_RS09635	COG2818	Glycosylase
FOB21_RS09640	COG1064	alcohol dehydrogenase
FOB21_RS09680	COG0675	Transposase, IS605 OrfB family
FOB21_RS09700	COG1309	transcriptional regulator
FOB21_RS09725	COG2233	PERMEase
FOB21_RS09745	COG0129	dihydroxy-acid dehydratase activity
FOB21_RS09770	COG0129	dihydroxy-acid dehydratase activity
FOB21_RS09785	COG0428	transporter
FOB21_RS09795	COG0733	neurotransmitter:sodium symporter activity
FOB21_RS09800	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_RS09810	COG0693	protein deglycase activity
FOB21_RS09840	COG2814	Major facilitator Superfamily
FOB21_RS09845	COG2814	Major facilitator Superfamily
FOB21_RS09875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB21_RS09890	COG0657	acetylesterase activity
FOB21_RS09950	COG0488	(ABC) transporter
FOB21_RS09955	COG1063	alcohol dehydrogenase
FOB21_RS09960	COG0187	DNA topoisomerase II activity
FOB21_RS09970	COG0592	DNA-directed DNA polymerase activity
FOB21_RS09975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB21_RS09985	COG0594	ribonuclease P activity
FOB21_RS09990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOB21_RS09995	COG0706	membrane insertase activity
FOB21_RS10005	COG3385	transposase activity
FOB21_RS10030	COG0402	S-adenosylhomocysteine deaminase activity
FOB21_RS10040	COG0861	Integral membrane protein TerC family
FOB21_RS10050	COG2388	GCN5-related N-acetyl-transferase
FOB21_RS10075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB21_RS10090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB21_RS10095	COG2951	lytic endotransglycosylase activity
FOB21_RS10100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB21_RS10105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB21_RS10140	COG2133	pyrroloquinoline quinone binding
FOB21_RS10155	COG1047	Peptidyl-prolyl cis-trans
FOB21_RS10160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB21_RS10165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB21_RS10170	COG0196	riboflavin kinase activity
FOB21_RS10180	COG1309	transcriptional regulator
FOB21_RS10185	COG1116	anion transmembrane transporter activity
FOB21_RS10190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB21_RS10195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_RS10200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB21_RS10205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB21_RS10210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB21_RS10210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB21_RS10230	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_RS10235	COG0546	phosphoglycolate phosphatase activity
FOB21_RS10240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB21_RS10245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_RS10250	COG1309	transcriptional regulator
FOB21_RS10255	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB21_RS10270	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB21_RS10275	COG0728	peptidoglycan biosynthetic process
FOB21_RS10280	COG5487	UPF0391 membrane protein
FOB21_RS10285	COG2983	Belongs to the UPF0260 family
FOB21_RS10290	COG3300	MHYT domain
FOB21_RS10290	COG5001	Diguanylate cyclase
FOB21_RS10295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB21_RS10300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB21_RS10310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB21_RS10315	COG2814	Major facilitator Superfamily
FOB21_RS10320	COG1335	isochorismatase
FOB21_RS10325	COG0385	Bile acid
FOB21_RS10355	COG3385	transposase activity
FOB21_RS10365	COG0753	catalase activity
FOB21_RS10405	COG2733	membrane
FOB21_RS10420	COG2918	glutathione biosynthetic process
FOB21_RS10425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOB21_RS10435	COG3150	esterase
FOB21_RS10455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB21_RS10480	COG1247	-acetyltransferase
FOB21_RS10510	COG3706	GGDEF domain
FOB21_RS10540	COG0708	Exodeoxyribonuclease III
FOB21_RS10545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB21_RS10550	COG1278	Cold shock
FOB21_RS10565	COG2132	Multicopper oxidase
FOB21_RS10575	COG3293	Transposase
FOB21_RS10585	COG0189	ligase activity
FOB21_RS10600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB21_RS10610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB21_RS10620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB21_RS10645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB21_RS10655	COG2119	membrane
FOB21_RS10660	COG0426	domain, Protein
FOB21_RS10660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB21_RS10685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB21_RS10710	COG1902	pentaerythritol trinitrate reductase activity
FOB21_RS10715	COG1519	Transferase
FOB21_RS10720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB21_RS10725	COG0668	transmembrane transport
FOB21_RS10730	COG3152	Membrane
FOB21_RS10735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB21_RS10745	COG0415	Belongs to the DNA photolyase family
FOB21_RS10750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_RS10755	COG0431	NADPH-dependent FMN reductase
FOB21_RS10770	COG0784	Response regulator, receiver
FOB21_RS10770	COG2205	protein histidine kinase activity
FOB21_RS10775	COG3162	membrane
FOB21_RS10780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB21_RS10790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB21_RS10805	COG3706	GGDEF domain
FOB21_RS10825	COG0352	thiamine-phosphate diphosphorylase activity
FOB21_RS10825	COG0351	phosphomethylpyrimidine kinase
FOB21_RS10825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB21_RS10835	COG2814	Major facilitator Superfamily
FOB21_RS10850	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FOB21_RS10945	COG0305	Participates in initiation and elongation during chromosome replication
FOB21_RS10985	COG3158	transport of potassium into the cell
FOB21_RS11020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB21_RS11055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOB21_RS11125	COG1024	Enoyl-CoA hydratase
FOB21_RS11125	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_RS11150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB21_RS11170	COG3275	phosphorelay sensor kinase activity
FOB21_RS11180	COG0181	hydroxymethylbilane synthase activity
FOB21_RS11200	COG0824	Thioesterase
FOB21_RS11230	COG0546	phosphoglycolate phosphatase activity
FOB21_RS11260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB21_RS11285	COG0081	regulation of translation
FOB21_RS11290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB21_RS11295	COG0222	ribosome binding
FOB21_RS11300	COG0085	RNA polymerase activity
FOB21_RS11305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB21_RS11325	COG2056	Na+-H+ antiporter family
FOB21_RS11330	COG3047	cAMP biosynthetic process
FOB21_RS11340	COG0326	Molecular chaperone. Has ATPase activity
FOB21_RS11370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOB21_RS11375	COG0427	acetyl-CoA hydrolase
FOB21_RS11405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB21_RS11435	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB21_RS11440	COG1074	ATP-dependent DNA helicase activity
FOB21_RS11445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_RS11450	COG3293	Transposase
FOB21_RS11455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB21_RS11460	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB21_RS11465	COG2841	Protein conserved in bacteria
FOB21_RS11470	COG0789	Transcriptional regulator
FOB21_RS11480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB21_RS11485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB21_RS11485	COG0475	glutathione-regulated potassium exporter activity
FOB21_RS11490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB21_RS11510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB21_RS11515	COG4535	Mg2 and Co2 transporter CorC
FOB21_RS11520	COG0425	Belongs to the sulfur carrier protein TusA family
FOB21_RS11525	COG0644	oxidoreductase
FOB21_RS11525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOB21_RS11535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB21_RS11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB21_RS11560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOB21_RS11570	COG0493	'glutamate synthase
FOB21_RS11595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB21_RS11615	COG0751	glycine-tRNA ligase activity
FOB21_RS11640	COG0471	metal ion transport
FOB21_RS11650	COG1983	PspC domain protein
FOB21_RS11675	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_RS11680	COG1530	ribonuclease E activity
FOB21_RS11685	COG0564	pseudouridine synthase activity
FOB21_RS11700	COG3971	2-oxopent-4-enoate hydratase activity
FOB21_RS11705	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FOB21_RS11735	COG0583	DNA-binding transcription factor activity
FOB21_RS11740	COG4638	Rieske (2fe-2S)
FOB21_RS11755	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_RS11760	COG3384	dioxygenase
FOB21_RS11765	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB21_RS11785	COG3011	Protein conserved in bacteria
FOB21_RS11790	COG0753	catalase activity
FOB21_RS11830	COG0583	DNA-binding transcription factor activity
FOB21_RS11840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB21_RS11855	COG0473	3-isopropylmalate dehydrogenase activity
FOB21_RS11920	COG1560	Kdo2-lipid A biosynthetic process
FOB21_RS11925	COG0488	(ABC) transporter
FOB21_RS11930	COG2900	Belongs to the SlyX family
FOB21_RS11960	COG1929	Belongs to the glycerate kinase type-1 family
FOB21_RS11965	COG0210	DNA helicase
FOB21_RS11985	COG4651	solute:proton antiporter activity
FOB21_RS11985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB21_RS12010	COG0788	formyltetrahydrofolate deformylase activity
FOB21_RS12055	COG3040	lipid binding
FOB21_RS12120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_RS12120	COG2813	Specifically methylates the guanine in position
FOB21_RS12125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_RS12130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB21_RS12140	COG4774	siderophore transport
FOB21_RS12155	COG4771	TonB-dependent receptor
FOB21_RS12165	COG0740	serine-type endopeptidase activity
FOB21_RS12180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB21_RS12180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB21_RS12190	COG0280	phosphate acetyltransferase
FOB21_RS12190	COG0857	belongs to the CobB CobQ family
FOB21_RS12195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB21_RS12205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_RS12205	COG0596	Alpha beta hydrolase
FOB21_RS12205	COG2226	methyltransferase
FOB21_RS12220	COG0793	Belongs to the peptidase S41A family
FOB21_RS12230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB21_RS12245	COG0084	hydrolase, TatD family'
FOB21_RS12270	COG1162	GTPase activity
FOB21_RS12275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB21_RS12290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB21_RS12300	COG1538	Outer membrane efflux protein
FOB21_RS12305	COG1136	(ABC) transporter
FOB21_RS12305	COG0577	efflux transmembrane transporter activity
FOB21_RS12310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_RS12335	COG0028	Belongs to the TPP enzyme family
FOB21_RS12340	COG0440	acetolactate synthase activity
FOB21_RS12345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB21_RS12380	COG2975	iron-sulfur cluster assembly
FOB21_RS12400	COG1426	Protein conserved in bacteria
FOB21_RS12420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB21_RS12435	COG0300	oxidoreductase activity
FOB21_RS12440	COG3956	TIGRFAM MazG family protein
FOB21_RS12445	COG1555	photosystem II stabilization
FOB21_RS12450	COG0617	tRNA 3'-terminal CCA addition
FOB21_RS12455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB21_RS12470	COG1660	Displays ATPase and GTPase activities
FOB21_RS12475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB21_RS12485	COG2205	protein histidine kinase activity
FOB21_RS12490	COG0675	Transposase, IS605 OrfB family
FOB21_RS12495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB21_RS12550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB21_RS12590	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS12595	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS12605	COG2205	protein histidine kinase activity
FOB21_RS12610	COG0745	RESPONSE REGULATOR receiver
FOB21_RS12620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB21_RS12635	COG2096	Adenosyltransferase
FOB21_RS12640	COG4206	TonB-dependent receptor
FOB21_RS12655	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_RS12675	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB21_RS12690	COG0625	glutathione transferase activity
FOB21_RS12700	COG1238	metal cluster binding
FOB21_RS12730	COG0072	phenylalanine-tRNA ligase activity
FOB21_RS12755	COG0248	Ppx GppA phosphatase
FOB21_RS12765	COG0037	tRNA processing
FOB21_RS12810	COG1764	response to oxidative stress
FOB21_RS12815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB21_RS12880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB21_RS12885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB21_RS12930	COG3293	Transposase
FOB21_RS12945	COG0494	nUDIX hydrolase
FOB21_RS12955	COG1214	PFAM Peptidase M22, glycoprotease
FOB21_RS12960	COG1968	undecaprenyl-diphosphatase activity
FOB21_RS12995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB21_RS13005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB21_RS13015	COG2814	Major facilitator Superfamily
FOB21_RS13020	COG2030	dehydratase
FOB21_RS13020	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_RS13025	COG3396	Phenylacetate-CoA oxygenase
FOB21_RS13030	COG3460	Phenylacetate-CoA oxygenase
FOB21_RS13035	COG3396	Phenylacetate-CoA oxygenase
FOB21_RS13040	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB21_RS13045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB21_RS13050	COG1024	Enoyl-CoA hydratase
FOB21_RS13055	COG1024	Enoyl-CoA hydratase
FOB21_RS13060	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_RS13065	COG0183	Belongs to the thiolase family
FOB21_RS13070	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FOB21_RS13075	COG3327	negative regulation of DNA-templated transcription, initiation
FOB21_RS13085	COG4106	trans-aconitate 2-methyltransferase activity
FOB21_RS13095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB21_RS13120	COG0730	response to heat
FOB21_RS13130	COG1196	nuclear chromosome segregation
FOB21_RS13140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB21_RS13150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB21_RS13155	COG2193	ferroxidase activity
FOB21_RS13195	COG0339	signal peptide processing
FOB21_RS13220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOB21_RS13225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOB21_RS13240	COG0009	L-threonylcarbamoyladenylate synthase
FOB21_RS13245	COG3101	peptidyl-lysine hydroxylation
FOB21_RS13250	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB21_RS13260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB21_RS13265	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_RS13270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB21_RS13275	COG1652	LysM domain
FOB21_RS13300	COG1113	amino acid transport
FOB21_RS13305	COG1981	membrane
FOB21_RS13320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB21_RS13335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB21_RS13345	COG0456	acetyltransferase
FOB21_RS13355	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB21_RS13360	COG0492	ferredoxin-NADP+ reductase activity
FOB21_RS13365	COG1674	ftsk spoiiie
FOB21_RS13365	COG0531	amino acid
FOB21_RS13395	COG0204	Acyl-transferase
FOB21_RS13400	COG2885	chlorophyll binding
FOB21_RS13405	COG0210	DNA helicase
FOB21_RS13410	COG0756	dUTP diphosphatase activity
FOB21_RS13415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB21_RS13420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB21_RS13425	COG0121	glutamine amidotransferase
FOB21_RS13445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB21_RS13450	COG0735	belongs to the Fur family
FOB21_RS13465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB21_RS13480	COG0420	3'-5' exonuclease activity
FOB21_RS13490	COG1090	epimerase
FOB21_RS13495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB21_RS13505	COG2050	protein possibly involved in aromatic compounds catabolism
FOB21_RS13510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB21_RS13520	COG0582	viral genome integration into host DNA
FOB21_RS13535	COG0629	single-stranded DNA binding
FOB21_RS13570	COG3646	Phage regulatory protein
FOB21_RS13735	COG4695	Portal protein
FOB21_RS13750	COG0582	viral genome integration into host DNA
FOB21_RS13845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOB21_RS13870	COG1674	ftsk spoiiie
FOB21_RS13885	COG3177	Filamentation induced by cAMP protein fic
FOB21_RS13915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_RS13920	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB21_RS13925	COG1136	(ABC) transporter
FOB21_RS13930	COG0783	Belongs to the Dps family
FOB21_RS13955	COG0500	methyltransferase
FOB21_RS13965	COG2223	nitrite transmembrane transporter activity
FOB21_RS13970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FOB21_RS13980	COG3293	Transposase
FOB21_RS13990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FOB21_RS14020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB21_RS14030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB21_RS14035	COG1077	Cell shape determining protein MreB Mrl
FOB21_RS14040	COG1792	Involved in formation and maintenance of cell shape
FOB21_RS14045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB21_RS14050	COG0424	maF-like protein
FOB21_RS14070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB21_RS14105	COG1113	amino acid transport
FOB21_RS14110	COG2828	Protein conserved in bacteria
FOB21_RS14115	COG0142	geranyltranstransferase activity
FOB21_RS14120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB21_RS14135	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB21_RS14160	COG2323	membrane
FOB21_RS14195	COG0525	valine-tRNA ligase activity
FOB21_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_RS14215	COG2066	Belongs to the glutaminase family
FOB21_RS14235	COG0306	phosphate transporter
FOB21_RS14275	COG4771	TonB-dependent receptor
FOB21_RS14300	COG4181	ATPase activity
FOB21_RS14305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB21_RS14330	COG0583	DNA-binding transcription factor activity
FOB21_RS14335	COG2267	carboxylic ester hydrolase activity
FOB21_RS14340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_RS14345	COG1773	rubredoxin
FOB21_RS14350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB21_RS14370	COG2354	Protein conserved in bacteria
FOB21_RS14375	COG2321	neutral zinc metallopeptidase
FOB21_RS14395	COG0589	response to stress
FOB21_RS14430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB21_RS14435	COG1053	succinate dehydrogenase
FOB21_RS14440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB21_RS14455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB21_RS14470	COG2268	Band 7 protein
FOB21_RS14510	COG3118	belongs to the thioredoxin family
FOB21_RS14515	COG4221	oxidoreductase activity
FOB21_RS14515	COG0604	alcohol dehydrogenase
FOB21_RS14515	COG3321	synthase
FOB21_RS14515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB21_RS14545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB21_RS14565	COG1597	lipid kinase activity
FOB21_RS14625	COG0742	ribosomal rna small subunit methyltransferase
FOB21_RS14630	COG0768	penicillin binding
FOB21_RS14655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB21_RS14660	COG2878	Part of a membrane complex involved in electron transport
FOB21_RS14665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB21_RS14675	COG3384	dioxygenase
FOB21_RS14685	COG2234	aminopeptidase activity
FOB21_RS14690	COG3385	transposase activity
FOB21_RS14700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB21_RS14720	COG1802	Transcriptional regulator
FOB21_RS14755	COG0006	proline dipeptidase activity
FOB21_RS14760	COG2155	Conserved Protein
FOB21_RS14770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB21_RS14775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB21_RS14790	COG3107	peptidoglycan biosynthetic process
FOB21_RS14805	COG0657	acetylesterase activity
FOB21_RS14825	COG0741	lytic transglycosylase activity
FOB21_RS14825	COG1388	LysM domain
FOB21_RS14825	COG1388	LysM domain
FOB21_RS14825	COG0741	lytic transglycosylase activity
FOB21_RS14830	COG4166	transmembrane transport
FOB21_RS14835	COG4174	ABC transporter (Permease)
FOB21_RS14840	COG4239	(ABC) transporter, permease
FOB21_RS14880	COG0833	amino acid
FOB21_RS14905	COG0418	dihydroorotase activity
FOB21_RS14910	COG3706	GGDEF domain
FOB21_RS14910	COG5001	Diguanylate cyclase
FOB21_RS14910	COG2203	Gaf domain
FOB21_RS14910	COG4251	negative regulation of phosphorylation
FOB21_RS14925	COG1902	pentaerythritol trinitrate reductase activity
FOB21_RS14925	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB21_RS14940	COG1741	Belongs to the pirin family
FOB21_RS14955	COG3739	integral membrane protein
FOB21_RS14970	COG3706	GGDEF domain
FOB21_RS14985	COG0302	gtp cyclohydrolase
FOB21_RS15000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB21_RS15005	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB21_RS15100	COG3385	transposase activity
FOB21_RS15160	COG0174	glutamine synthetase
FOB21_RS15175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOB21_RS15215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB21_RS15220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB21_RS15225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB21_RS15235	COG0596	Alpha beta hydrolase
FOB21_RS15240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_RS15245	COG1335	isochorismatase
FOB21_RS15250	COG0251	oxidation-reduction process
FOB21_RS15255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB21_RS15260	COG2233	PERMEase
FOB21_RS15265	COG2084	Dehydrogenase
FOB21_RS15280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB21_RS15285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB21_RS15295	COG2175	clavaminate synthase activity
FOB21_RS15320	COG0556	nucleotide-excision repair
FOB21_RS15345	COG1733	regulation of RNA biosynthetic process
FOB21_RS15355	COG3293	Transposase
FOB21_RS15370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB21_RS15375	COG0671	phosphoesterase, PA-phosphatase related
FOB21_RS15385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB21_RS15390	COG0076	glutamate decarboxylase activity
FOB21_RS15395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB21_RS15400	COG0573	inorganic phosphate transmembrane transporter activity
FOB21_RS15410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB21_RS15415	COG0616	signal peptide processing
FOB21_RS15455	COG0482	sulfurtransferase activity
FOB21_RS15470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB21_RS15475	COG1686	Belongs to the peptidase S11 family
FOB21_RS15495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOB21_RS15505	COG0583	DNA-binding transcription factor activity
FOB21_RS15510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB21_RS15515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB21_RS15520	COG1067	ATP-dependent peptidase activity
FOB21_RS15540	COG0254	rRNA binding
FOB21_RS15555	COG1509	lysine 2,3-aminomutase activity
FOB21_RS15560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB21_RS15565	COG1966	Carbon starvation protein
FOB21_RS15570	COG2879	small protein
FOB21_RS15575	COG0714	Associated with various cellular activities
FOB21_RS15625	COG0640	Transcriptional regulator
FOB21_RS15635	COG0798	PFAM Bile acid sodium symporter
FOB21_RS15640	COG0431	NADPH-dependent FMN reductase
FOB21_RS15645	COG2072	flavoprotein involved in K transport
FOB21_RS15650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB21_RS15660	COG0642	Histidine kinase
FOB21_RS15665	COG0745	RESPONSE REGULATOR receiver
FOB21_RS15670	COG4232	protein-disulfide reductase activity
FOB21_RS15675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB21_RS15690	COG0640	Transcriptional regulator
FOB21_RS15720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB21_RS15725	COG1765	OsmC-like protein
FOB21_RS15735	COG0667	Aldo Keto reductase
FOB21_RS15760	COG0540	Belongs to the ATCase OTCase family
FOB21_RS15775	COG2031	fatty acid transporter
FOB21_RS15780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB21_RS15795	COG4770	biotin carboxylase activity
FOB21_RS15800	COG1024	Enoyl-CoA hydratase
FOB21_RS15805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB21_RS15810	COG1960	acyl-CoA dehydrogenase activity
FOB21_RS15815	COG1309	transcriptional regulator
FOB21_RS15820	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_RS15840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB21_RS15845	COG0659	secondary active sulfate transmembrane transporter activity
FOB21_RS15850	COG0625	glutathione transferase activity
FOB21_RS15865	COG2363	Small membrane protein
FOB21_RS15880	COG1278	Cold shock
FOB21_RS15885	COG0513	Belongs to the DEAD box helicase family
FOB21_RS15895	COG0778	Nitroreductase
FOB21_RS15920	COG0167	dihydroorotate dehydrogenase activity
FOB21_RS15935	COG0501	Belongs to the peptidase M48B family
FOB21_RS15950	COG4783	chaperone-mediated protein folding
FOB21_RS15975	COG2203	Gaf domain
FOB21_RS15975	COG2199	diguanylate cyclase activity
FOB21_RS16080	COG0612	Peptidase, M16
FOB21_RS16115	COG3025	triphosphatase activity
FOB21_RS16130	COG0352	thiamine-phosphate diphosphorylase activity
FOB21_RS16180	COG1309	transcriptional regulator
FOB21_RS16235	COG2391	methyltransferase activity
FOB21_RS16255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB21_RS16265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB21_RS16280	COG3335	DDE superfamily endonuclease
FOB21_RS16300	COG0505	Belongs to the CarA family
FOB21_RS16310	COG0625	glutathione transferase activity
FOB21_RS16340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB21_RS16340	COG0517	IMP dehydrogenase activity
FOB21_RS16345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOB21_RS16355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB21_RS16360	COG1137	ATPase activity
FOB21_RS16395	COG4122	O-methyltransferase activity
FOB21_RS16405	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOB21_RS16440	COG2011	ABC-type metal ion transport system permease component
FOB21_RS16445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB21_RS16450	COG1464	Belongs to the NlpA lipoprotein family
FOB21_RS16480	COG0151	Belongs to the GarS family
FOB21_RS16485	COG0138	bifunctional purine biosynthesis protein purh
FOB21_RS16490	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOB21_RS16525	COG2814	Major facilitator Superfamily
FOB21_RS16530	COG2814	Major facilitator Superfamily
FOB21_RS16545	COG3852	Histidine kinase
FOB21_RS16565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB21_RS16570	COG0575	Belongs to the CDS family
FOB21_RS16585	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB21_RS16595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB21_RS16600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB21_RS16605	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB21_RS16620	COG2137	regulation of response to DNA damage stimulus
FOB21_RS16625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB21_RS16630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB21_RS16635	COG1011	Hydrolase
FOB21_RS16650	COG0268	Binds directly to 16S ribosomal RNA
FOB21_RS16655	COG0702	epimerase
FOB21_RS16660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB21_RS16670	COG2197	response regulator
FOB21_RS16675	COG4585	Histidine kinase
FOB21_RS16680	COG2850	peptidyl-arginine hydroxylation
FOB21_RS16685	COG0424	maF-like protein
FOB21_RS16710	COG0697	spore germination
FOB21_RS16720	COG0778	Nitroreductase
FOB21_RS16765	COG3781	membrane
FOB21_RS16795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB21_RS16800	COG1027	Aspartate ammonia-lyase
FOB21_RS16810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB21_RS16845	COG0316	Belongs to the HesB IscA family
FOB21_RS16850	COG0822	iron-sulfur transferase activity
FOB21_RS16875	COG0776	regulation of translation
FOB21_RS16880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB21_RS16900	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOB21_RS16910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB21_RS16930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB21_RS16935	COG0569	domain protein
FOB21_RS16960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB21_RS16965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB21_RS16985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB21_RS17020	COG4456	Virulence-associated protein
FOB21_RS17060	COG2431	L-lysine efflux transmembrane transporter activity