locus-tag	class	description
J7649_RS00010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J7649_RS00015	COG0358	DNA primase activity
J7649_RS00025	COG0564	pseudouridine synthase activity
J7649_RS00050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J7649_RS00070	COG0110	maltose O-acetyltransferase activity
J7649_RS00075	COG0251	oxidation-reduction process
J7649_RS00080	COG1309	transcriptional regulator
J7649_RS00090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J7649_RS00095	COG0505	Belongs to the CarA family
J7649_RS00125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J7649_RS00135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J7649_RS00170	COG1253	flavin adenine dinucleotide binding
J7649_RS00195	COG2239	Acts as a magnesium transporter
J7649_RS00205	COG0501	Belongs to the peptidase M48B family
J7649_RS00210	COG1196	nuclear chromosome segregation
J7649_RS00210	COG0739	heme binding
J7649_RS00210	COG0741	lytic transglycosylase activity
J7649_RS00215	COG0037	tRNA processing
J7649_RS00230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J7649_RS00250	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J7649_RS00265	COG5001	Diguanylate cyclase
J7649_RS00265	COG1716	ATPase activity
J7649_RS00270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J7649_RS00275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J7649_RS00280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J7649_RS00325	COG1115	amino acid carrier protein
J7649_RS00330	COG1113	amino acid transport
J7649_RS00340	COG0019	diaminopimelate decarboxylase activity
J7649_RS00355	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J7649_RS00365	COG1522	sequence-specific DNA binding
J7649_RS00370	COG1280	lysine exporter protein (LysE YggA)
J7649_RS00410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J7649_RS00430	COG1671	Belongs to the UPF0178 family
J7649_RS00450	COG1136	(ABC) transporter
J7649_RS00455	COG0658	competence protein
J7649_RS00455	COG2333	competence protein COMEC
J7649_RS00470	COG2267	carboxylic ester hydrolase activity
J7649_RS00475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J7649_RS00480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J7649_RS00485	COG0628	permease
J7649_RS00490	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J7649_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J7649_RS00540	COG0823	Involved in the tonB-independent uptake of proteins
J7649_RS00560	COG0824	Thioesterase
J7649_RS00565	COG1473	amidohydrolase
J7649_RS00580	COG2255	four-way junction helicase activity
J7649_RS00605	COG0047	phosphoribosylformylglycinamidine synthase activity
J7649_RS00605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J7649_RS00630	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
J7649_RS00645	COG0778	Nitroreductase
J7649_RS00655	COG1051	belongs to the nudix hydrolase family
J7649_RS00655	COG1056	cytidyltransferase-related domain
J7649_RS00660	COG0583	DNA-binding transcription factor activity
J7649_RS00670	COG2353	YceI-like domain
J7649_RS00675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J7649_RS00685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J7649_RS00690	COG0602	queuosine metabolic process
J7649_RS00710	COG0583	DNA-binding transcription factor activity
J7649_RS00715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J7649_RS00720	COG4208	sulfate ABC transporter
J7649_RS00735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J7649_RS00740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J7649_RS00750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J7649_RS00770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J7649_RS00795	COG0571	ribonuclease III activity
J7649_RS00800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J7649_RS00815	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J7649_RS00840	COG0534	Mate efflux family protein
J7649_RS00845	COG0436	Aminotransferase
J7649_RS00855	COG0052	Belongs to the universal ribosomal protein uS2 family
J7649_RS00880	COG2951	lytic endotransglycosylase activity
J7649_RS00895	COG0842	Transport permease protein
J7649_RS00900	COG1131	(ABC) transporter
J7649_RS00910	COG0582	viral genome integration into host DNA
J7649_RS00990	COG0737	Belongs to the 5'-nucleotidase family
J7649_RS01035	COG2814	Major facilitator Superfamily
J7649_RS01070	COG3706	GGDEF domain
J7649_RS01100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J7649_RS01120	COG3634	alkyl hydroperoxide reductase activity
J7649_RS01125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J7649_RS01130	COG0826	peptidase U32
J7649_RS01160	COG1720	tRNA m6t6A37 methyltransferase activity
J7649_RS01180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J7649_RS01195	COG0642	Histidine kinase
J7649_RS01205	COG0352	thiamine-phosphate diphosphorylase activity
J7649_RS01215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J7649_RS01220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J7649_RS01225	COG3139	Protein of unknown function (DUF1315)
J7649_RS01235	COG1301	dicarboxylic acid transport
J7649_RS01240	COG1960	acyl-CoA dehydrogenase activity
J7649_RS01245	COG0693	protein deglycase activity
J7649_RS01255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J7649_RS01260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J7649_RS01285	COG2252	PERMEase
J7649_RS01290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J7649_RS01310	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J7649_RS01320	COG0527	aspartate kinase activity
J7649_RS01325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J7649_RS01330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J7649_RS01345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J7649_RS01360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J7649_RS01380	COG1252	NADH dehydrogenase
J7649_RS01385	COG1686	Belongs to the peptidase S11 family
J7649_RS01395	COG2050	protein possibly involved in aromatic compounds catabolism
J7649_RS01430	COG0436	Aminotransferase
J7649_RS01435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J7649_RS01440	COG0386	Belongs to the glutathione peroxidase family
J7649_RS01450	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J7649_RS01470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J7649_RS01480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J7649_RS01485	COG0012	GTP binding
J7649_RS01515	COG0204	Acyl-transferase
J7649_RS01565	COG0830	nickel cation binding
J7649_RS01580	COG0829	nickel cation binding
J7649_RS01585	COG0831	urea catabolic process
J7649_RS01600	COG0804	urea catabolic process
J7649_RS01620	COG2351	hydroxyisourate hydrolase activity
J7649_RS01625	COG2233	PERMEase
J7649_RS01640	COG4266	Belongs to the allantoicase family
J7649_RS01645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J7649_RS01650	COG0583	DNA-binding transcription factor activity
J7649_RS01660	COG2233	PERMEase
J7649_RS01665	COG3248	Nucleoside-binding outer membrane protein
J7649_RS01680	COG0583	DNA-binding transcription factor activity
J7649_RS01735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J7649_RS01755	COG1401	restriction endodeoxyribonuclease activity
J7649_RS01755	COG1401	restriction endodeoxyribonuclease activity
J7649_RS01765	COG0210	DNA helicase
J7649_RS01770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J7649_RS01815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J7649_RS01815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J7649_RS01850	COG3634	alkyl hydroperoxide reductase activity
J7649_RS01875	COG1643	Atp-dependent helicase
J7649_RS01895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J7649_RS01930	COG0802	atpase or kinase
J7649_RS01935	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J7649_RS01945	COG1923	regulation of RNA biosynthetic process
J7649_RS01950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J7649_RS01960	COG3178	'Phosphotransferase
J7649_RS01965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J7649_RS01975	COG1192	Involved in chromosome partitioning
J7649_RS01980	COG1475	DNA binding
J7649_RS01985	COG0811	peptide transport
J7649_RS01995	COG1132	(ABC) transporter
J7649_RS02000	COG1663	tetraacyldisaccharide 4'-kinase activity
J7649_RS02020	COG0084	hydrolase, TatD family'
J7649_RS02025	COG1309	transcriptional regulator
J7649_RS02055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J7649_RS02085	COG0776	regulation of translation
J7649_RS02105	COG2431	L-lysine efflux transmembrane transporter activity
J7649_RS02120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J7649_RS02125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J7649_RS02145	COG1253	flavin adenine dinucleotide binding
J7649_RS02165	COG0308	aminopeptidase N
J7649_RS02175	COG0589	response to stress
J7649_RS02180	COG0589	response to stress
J7649_RS02195	COG3135	benzoate transporter
J7649_RS02205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J7649_RS02210	COG0583	DNA-binding transcription factor activity
J7649_RS02225	COG0183	Belongs to the thiolase family
J7649_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS02240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J7649_RS02250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J7649_RS02255	COG0824	Thioesterase
J7649_RS02260	COG1454	alcohol dehydrogenase
J7649_RS02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J7649_RS02285	COG0069	glutamate synthase activity
J7649_RS02295	COG2308	Evidence 4 Homologs of previously reported genes of
J7649_RS02305	COG1305	Transglutaminase-like
J7649_RS02320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J7649_RS02325	COG0305	Participates in initiation and elongation during chromosome replication
J7649_RS02340	COG0360	Binds together with S18 to 16S ribosomal RNA
J7649_RS02350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J7649_RS02355	COG1845	cytochrome c oxidase, subunit III
J7649_RS02360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J7649_RS02365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J7649_RS02390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7649_RS02405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J7649_RS02410	COG2890	protein-(glutamine-N5) methyltransferase activity
J7649_RS02430	COG1960	acyl-CoA dehydrogenase activity
J7649_RS02435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J7649_RS02445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J7649_RS02480	COG0477	Major facilitator Superfamily
J7649_RS02485	COG0729	surface antigen
J7649_RS02535	COG1570	exodeoxyribonuclease VII activity
J7649_RS02600	COG0583	DNA-binding transcription factor activity
J7649_RS02620	COG0446	pyridine nucleotide-disulphide oxidoreductase
J7649_RS02620	COG1902	pentaerythritol trinitrate reductase activity
J7649_RS02650	COG0148	phosphopyruvate hydratase activity
J7649_RS02665	COG0772	Belongs to the SEDS family
J7649_RS02675	COG4890	Cyd operon protein YbgT
J7649_RS02680	COG1294	oxidase, subunit
J7649_RS02700	COG0537	adenosine 5'-monophosphoramidase activity
J7649_RS02730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J7649_RS02750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J7649_RS02760	COG0133	tryptophan synthase activity
J7649_RS02765	COG0517	IMP dehydrogenase activity
J7649_RS02795	COG0612	Peptidase, M16
J7649_RS02800	COG0552	protein localization to endoplasmic reticulum
J7649_RS02850	COG0456	acetyltransferase
J7649_RS02860	COG1960	acyl-CoA dehydrogenase activity
J7649_RS02920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J7649_RS02925	COG0730	response to heat
J7649_RS02930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J7649_RS02935	COG2207	Transcriptional regulator
J7649_RS02940	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J7649_RS02945	COG1960	acyl-CoA dehydrogenase activity
J7649_RS02950	COG2169	Transcriptional regulator
J7649_RS02965	COG1271	oxidase subunit
J7649_RS02970	COG1294	oxidase, subunit
J7649_RS02980	COG1525	nuclease
J7649_RS03035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J7649_RS03040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J7649_RS03050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J7649_RS03060	COG2801	Transposase and inactivated derivatives
J7649_RS03070	COG2801	Transposase and inactivated derivatives
J7649_RS03080	COG2814	Major facilitator Superfamily
J7649_RS03085	COG0509	glycine decarboxylation via glycine cleavage system
J7649_RS03095	COG1132	(ABC) transporter
J7649_RS03100	COG0668	transmembrane transport
J7649_RS03105	COG3122	Protein conserved in bacteria
J7649_RS03125	COG0640	Transcriptional regulator
J7649_RS03130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J7649_RS03140	COG0789	Transcriptional regulator
J7649_RS03155	COG1960	acyl-CoA dehydrogenase activity
J7649_RS03160	COG0183	Belongs to the thiolase family
J7649_RS03175	COG3293	Transposase
J7649_RS03190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J7649_RS03195	COG0183	Belongs to the thiolase family
J7649_RS03200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J7649_RS03205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J7649_RS03210	COG3135	benzoate transporter
J7649_RS03215	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS03220	COG0543	2 iron, 2 sulfur cluster binding
J7649_RS03220	COG0633	Ferredoxin
J7649_RS03225	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J7649_RS03230	COG4638	Rieske (2fe-2S)
J7649_RS03240	COG4829	muconolactone delta-isomerase
J7649_RS03245	COG4948	Mandelate Racemase Muconate Lactonizing
J7649_RS03250	COG0583	DNA-binding transcription factor activity
J7649_RS03255	COG2814	Major facilitator Superfamily
J7649_RS03265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J7649_RS03270	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS03275	COG1017	nitric oxide dioxygenase activity
J7649_RS03275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J7649_RS03290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J7649_RS03310	COG0439	Biotin carboxylase
J7649_RS03320	COG0864	Transcriptional regulator
J7649_RS03355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7649_RS03360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J7649_RS03360	COG1116	anion transmembrane transporter activity
J7649_RS03370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J7649_RS03375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J7649_RS03380	COG0243	molybdopterin cofactor binding
J7649_RS03390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J7649_RS03400	COG0314	molybdopterin synthase activity
J7649_RS03405	COG0315	cyclic pyranopterin monophosphate synthase activity
J7649_RS03405	COG0521	Mo-molybdopterin cofactor biosynthetic process
J7649_RS03410	COG0303	'Molybdopterin
J7649_RS03415	COG0725	ABC transporter, periplasmic molybdate-binding protein
J7649_RS03420	COG4149	molybdate abc transporter
J7649_RS03425	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J7649_RS03430	COG2223	nitrite transmembrane transporter activity
J7649_RS03435	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
J7649_RS03440	COG2116	formate transmembrane transporter activity
J7649_RS03445	COG0515	serine threonine protein kinase
J7649_RS03460	COG3293	Transposase
J7649_RS03465	COG0583	DNA-binding transcription factor activity
J7649_RS03485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J7649_RS03490	COG1309	transcriptional regulator
J7649_RS03515	COG1944	ATP diphosphatase activity
J7649_RS03520	COG0644	oxidoreductase
J7649_RS03520	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J7649_RS03530	COG1960	acyl-CoA dehydrogenase activity
J7649_RS03535	COG1960	acyl-CoA dehydrogenase activity
J7649_RS03540	COG2814	Major facilitator Superfamily
J7649_RS03545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J7649_RS03550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J7649_RS03555	COG5001	Diguanylate cyclase
J7649_RS03560	COG2814	Major facilitator Superfamily
J7649_RS03570	COG2814	Major facilitator Superfamily
J7649_RS03580	COG1250	3-hydroxyacyl-CoA dehydrogenase
J7649_RS03585	COG0183	Belongs to the thiolase family
J7649_RS03595	COG0235	Class ii aldolase
J7649_RS03605	COG1024	Enoyl-CoA hydratase
J7649_RS03615	COG1960	acyl-CoA dehydrogenase activity
J7649_RS03630	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS03635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J7649_RS03640	COG2814	Major facilitator Superfamily
J7649_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS03655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J7649_RS03665	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS03690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J7649_RS03695	COG1960	acyl-CoA dehydrogenase activity
J7649_RS03700	COG1024	Enoyl-CoA hydratase
J7649_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS03730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J7649_RS03735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J7649_RS03740	COG1012	belongs to the aldehyde dehydrogenase family
J7649_RS03770	COG2351	hydroxyisourate hydrolase activity
J7649_RS03790	COG4266	Belongs to the allantoicase family
J7649_RS03795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J7649_RS03800	COG0583	DNA-binding transcription factor activity
J7649_RS03815	COG3845	ABC transporter
J7649_RS03825	COG1079	Belongs to the binding-protein-dependent transport system permease family
J7649_RS03840	COG2194	sulfuric ester hydrolase activity
J7649_RS03845	COG0745	RESPONSE REGULATOR receiver
J7649_RS03850	COG0642	Histidine kinase
J7649_RS03870	COG1022	Amp-dependent synthetase and ligase
J7649_RS03880	COG0300	oxidoreductase activity
J7649_RS03890	COG0596	Alpha beta hydrolase
J7649_RS03920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J7649_RS03955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J7649_RS03960	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J7649_RS03970	COG0439	Biotin carboxylase
J7649_RS03990	COG2814	Major facilitator Superfamily
J7649_RS03995	COG0753	catalase activity
J7649_RS04045	COG0372	Belongs to the citrate synthase family
J7649_RS04075	COG0542	response to heat
J7649_RS04080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J7649_RS04100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J7649_RS04105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J7649_RS04115	COG0569	domain protein
J7649_RS04120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J7649_RS04140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J7649_RS04150	COG1585	Membrane protein implicated in regulation of membrane protease activity
J7649_RS04170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J7649_RS04175	COG0776	regulation of translation
J7649_RS04200	COG0822	iron-sulfur transferase activity
J7649_RS04205	COG0316	Belongs to the HesB IscA family
J7649_RS04235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J7649_RS04245	COG1027	Aspartate ammonia-lyase
J7649_RS04250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J7649_RS04280	COG3781	membrane
J7649_RS04315	COG0778	Nitroreductase
J7649_RS04325	COG0697	spore germination
J7649_RS04350	COG0424	maF-like protein
J7649_RS04355	COG2850	peptidyl-arginine hydroxylation
J7649_RS04360	COG4585	Histidine kinase
J7649_RS04365	COG2197	response regulator
J7649_RS04375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J7649_RS04380	COG0702	epimerase
J7649_RS04385	COG0268	Binds directly to 16S ribosomal RNA
J7649_RS04400	COG1011	Hydrolase
J7649_RS04405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J7649_RS04410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J7649_RS04415	COG2137	regulation of response to DNA damage stimulus
J7649_RS04430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J7649_RS04435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J7649_RS04450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J7649_RS04465	COG0575	Belongs to the CDS family
J7649_RS04470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J7649_RS04490	COG3852	Histidine kinase
J7649_RS04510	COG2814	Major facilitator Superfamily
J7649_RS04545	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J7649_RS04550	COG0138	bifunctional purine biosynthesis protein purh
J7649_RS04570	COG1464	Belongs to the NlpA lipoprotein family
J7649_RS04575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J7649_RS04580	COG2011	ABC-type metal ion transport system permease component
J7649_RS04615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J7649_RS04625	COG4122	O-methyltransferase activity
J7649_RS04660	COG1137	ATPase activity
J7649_RS04665	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J7649_RS04675	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J7649_RS04680	COG0517	IMP dehydrogenase activity
J7649_RS04680	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J7649_RS04710	COG0625	glutathione transferase activity
J7649_RS04715	COG0505	Belongs to the CarA family
J7649_RS04735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J7649_RS04745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J7649_RS04755	COG2391	methyltransferase activity
J7649_RS04810	COG1309	transcriptional regulator
J7649_RS04830	COG0564	pseudouridine synthase activity
J7649_RS04855	COG0352	thiamine-phosphate diphosphorylase activity
J7649_RS04870	COG3025	triphosphatase activity
J7649_RS04895	COG0612	Peptidase, M16
J7649_RS04995	COG2199	diguanylate cyclase activity
J7649_RS04995	COG2203	Gaf domain
J7649_RS05020	COG4783	chaperone-mediated protein folding
J7649_RS05035	COG0501	Belongs to the peptidase M48B family
J7649_RS05050	COG0167	dihydroorotate dehydrogenase activity
J7649_RS05075	COG0778	Nitroreductase
J7649_RS05085	COG0513	Belongs to the DEAD box helicase family
J7649_RS05090	COG1278	Cold shock
J7649_RS05105	COG2363	Small membrane protein
J7649_RS05120	COG0625	glutathione transferase activity
J7649_RS05125	COG0659	secondary active sulfate transmembrane transporter activity
J7649_RS05130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J7649_RS05150	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS05155	COG1309	transcriptional regulator
J7649_RS05160	COG1960	acyl-CoA dehydrogenase activity
J7649_RS05165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J7649_RS05170	COG1024	Enoyl-CoA hydratase
J7649_RS05175	COG4770	biotin carboxylase activity
J7649_RS05190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J7649_RS05195	COG2031	fatty acid transporter
J7649_RS05210	COG0540	Belongs to the ATCase OTCase family
J7649_RS05235	COG0667	Aldo Keto reductase
J7649_RS05245	COG1765	OsmC-like protein
J7649_RS05250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J7649_RS05270	COG0714	Associated with various cellular activities
J7649_RS05275	COG2879	small protein
J7649_RS05280	COG1966	Carbon starvation protein
J7649_RS05285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J7649_RS05290	COG1509	lysine 2,3-aminomutase activity
J7649_RS05305	COG0254	rRNA binding
J7649_RS05325	COG1067	ATP-dependent peptidase activity
J7649_RS05330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J7649_RS05335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J7649_RS05340	COG0583	DNA-binding transcription factor activity
J7649_RS05350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J7649_RS05365	COG1686	Belongs to the peptidase S11 family
J7649_RS05370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J7649_RS05385	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J7649_RS05385	COG2755	lipolytic protein G-D-S-L family
J7649_RS05395	COG0482	sulfurtransferase activity
J7649_RS05425	COG0616	signal peptide processing
J7649_RS05430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J7649_RS05440	COG0573	inorganic phosphate transmembrane transporter activity
J7649_RS05445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J7649_RS05450	COG0076	glutamate decarboxylase activity
J7649_RS05455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J7649_RS05465	COG0671	phosphoesterase, PA-phosphatase related
J7649_RS05470	COG0629	single-stranded DNA binding
J7649_RS05520	COG0582	viral genome integration into host DNA
J7649_RS05525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J7649_RS05535	COG1733	regulation of RNA biosynthetic process
J7649_RS05555	COG0556	nucleotide-excision repair
J7649_RS05580	COG2175	clavaminate synthase activity
J7649_RS05590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J7649_RS05595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J7649_RS05600	COG1960	acyl-CoA dehydrogenase activity
J7649_RS05610	COG2084	Dehydrogenase
J7649_RS05615	COG2233	PERMEase
J7649_RS05620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J7649_RS05625	COG0251	oxidation-reduction process
J7649_RS05630	COG1335	isochorismatase
J7649_RS05635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7649_RS05640	COG0596	Alpha beta hydrolase
J7649_RS05650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J7649_RS05655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J7649_RS05660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J7649_RS05705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J7649_RS05720	COG0174	glutamine synthetase
J7649_RS05725	COG0512	Glutamine amidotransferase of anthranilate synthase
J7649_RS05730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J7649_RS05745	COG0302	gtp cyclohydrolase
J7649_RS05760	COG3706	GGDEF domain
J7649_RS05775	COG3739	integral membrane protein
J7649_RS05790	COG1741	Belongs to the pirin family
J7649_RS05805	COG1902	pentaerythritol trinitrate reductase activity
J7649_RS05805	COG0446	pyridine nucleotide-disulphide oxidoreductase
J7649_RS05820	COG2203	Gaf domain
J7649_RS05820	COG3706	GGDEF domain
J7649_RS05820	COG4251	negative regulation of phosphorylation
J7649_RS05820	COG5001	Diguanylate cyclase
J7649_RS05825	COG0418	dihydroorotase activity
J7649_RS05840	COG4771	TonB-dependent receptor
J7649_RS05855	COG0833	amino acid
J7649_RS05895	COG4239	(ABC) transporter, permease
J7649_RS05900	COG4174	ABC transporter (Permease)
J7649_RS05905	COG4166	transmembrane transport
J7649_RS05910	COG0741	lytic transglycosylase activity
J7649_RS05910	COG1388	LysM domain
J7649_RS05910	COG0741	lytic transglycosylase activity
J7649_RS05910	COG1388	LysM domain
J7649_RS05925	COG2816	NAD+ diphosphatase activity
J7649_RS05930	COG0657	acetylesterase activity
J7649_RS05945	COG3107	peptidoglycan biosynthetic process
J7649_RS05960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J7649_RS05965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J7649_RS05975	COG2155	Conserved Protein
J7649_RS05980	COG0006	proline dipeptidase activity
J7649_RS06015	COG1802	Transcriptional regulator
J7649_RS06040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J7649_RS06050	COG2234	aminopeptidase activity
J7649_RS06060	COG3384	dioxygenase
J7649_RS06070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J7649_RS06075	COG2878	Part of a membrane complex involved in electron transport
J7649_RS06080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J7649_RS06105	COG0768	penicillin binding
J7649_RS06110	COG0742	ribosomal rna small subunit methyltransferase
J7649_RS06175	COG1597	lipid kinase activity
J7649_RS06195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J7649_RS06220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J7649_RS06220	COG0604	alcohol dehydrogenase
J7649_RS06220	COG3321	synthase
J7649_RS06220	COG4221	oxidoreductase activity
J7649_RS06225	COG3118	belongs to the thioredoxin family
J7649_RS06255	COG2268	Band 7 protein
J7649_RS06270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J7649_RS06285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J7649_RS06290	COG1053	succinate dehydrogenase
J7649_RS06295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J7649_RS06330	COG0589	response to stress
J7649_RS06350	COG2321	neutral zinc metallopeptidase
J7649_RS06355	COG2354	Protein conserved in bacteria
J7649_RS06375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J7649_RS06380	COG1773	rubredoxin
J7649_RS06385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J7649_RS06390	COG2267	carboxylic ester hydrolase activity
J7649_RS06395	COG0583	DNA-binding transcription factor activity
J7649_RS06420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J7649_RS06425	COG4181	ATPase activity
J7649_RS06450	COG4771	TonB-dependent receptor
J7649_RS06470	COG0306	phosphate transporter
J7649_RS06485	COG2376	Dihydroxyacetone kinase
J7649_RS06490	COG2066	Belongs to the glutaminase family
J7649_RS06495	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS06505	COG0525	valine-tRNA ligase activity
J7649_RS06515	COG2852	Protein conserved in bacteria
J7649_RS06530	COG2323	membrane
J7649_RS06535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J7649_RS06555	COG1752	Esterase of the alpha-beta hydrolase superfamily
J7649_RS06570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J7649_RS06575	COG0142	geranyltranstransferase activity
J7649_RS06580	COG2828	Protein conserved in bacteria
J7649_RS06585	COG1113	amino acid transport
J7649_RS06615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J7649_RS06630	COG0424	maF-like protein
J7649_RS06635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J7649_RS06640	COG1792	Involved in formation and maintenance of cell shape
J7649_RS06645	COG1077	Cell shape determining protein MreB Mrl
J7649_RS06650	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J7649_RS06660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J7649_RS06690	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J7649_RS06705	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
J7649_RS06710	COG2223	nitrite transmembrane transporter activity
J7649_RS06720	COG0500	methyltransferase
J7649_RS06745	COG0783	Belongs to the Dps family
J7649_RS06750	COG1136	(ABC) transporter
J7649_RS06760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J7649_RS06775	COG1012	belongs to the aldehyde dehydrogenase family
J7649_RS06795	COG2186	Transcriptional regulator
J7649_RS06800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J7649_RS06805	COG2814	Major facilitator Superfamily
J7649_RS06810	COG2084	Dehydrogenase
J7649_RS06820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J7649_RS06840	COG0129	dihydroxy-acid dehydratase activity
J7649_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
J7649_RS06875	COG3177	Filamentation induced by cAMP protein fic
J7649_RS06890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J7649_RS06895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J7649_RS06925	COG0640	Transcriptional regulator
J7649_RS06935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J7649_RS06950	COG0642	Histidine kinase
J7649_RS06980	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J7649_RS07035	COG0582	viral genome integration into host DNA
J7649_RS07045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J7649_RS07050	COG2050	protein possibly involved in aromatic compounds catabolism
J7649_RS07060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J7649_RS07065	COG1090	epimerase
J7649_RS07075	COG0420	3'-5' exonuclease activity
J7649_RS07090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J7649_RS07105	COG0735	belongs to the Fur family
J7649_RS07110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J7649_RS07130	COG0121	glutamine amidotransferase
J7649_RS07135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J7649_RS07140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J7649_RS07145	COG0756	dUTP diphosphatase activity
J7649_RS07150	COG0210	DNA helicase
J7649_RS07155	COG2885	chlorophyll binding
J7649_RS07160	COG0204	Acyl-transferase
J7649_RS07190	COG1674	ftsk spoiiie
J7649_RS07190	COG0531	amino acid
J7649_RS07195	COG0492	ferredoxin-NADP+ reductase activity
J7649_RS07200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J7649_RS07210	COG0456	acetyltransferase
J7649_RS07220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J7649_RS07235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J7649_RS07250	COG1981	membrane
J7649_RS07255	COG1113	amino acid transport
J7649_RS07260	COG0251	oxidation-reduction process
J7649_RS07280	COG1652	LysM domain
J7649_RS07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J7649_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS07295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J7649_RS07305	COG1399	metal-binding, possibly nucleic acid-binding protein
J7649_RS07310	COG3101	peptidyl-lysine hydroxylation
J7649_RS07315	COG0009	L-threonylcarbamoyladenylate synthase
J7649_RS07330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J7649_RS07335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J7649_RS07360	COG0339	signal peptide processing
J7649_RS07400	COG2193	ferroxidase activity
J7649_RS07405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J7649_RS07410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J7649_RS07420	COG1196	nuclear chromosome segregation
J7649_RS07430	COG0730	response to heat
J7649_RS07455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J7649_RS07465	COG4106	trans-aconitate 2-methyltransferase activity
J7649_RS07475	COG3327	negative regulation of DNA-templated transcription, initiation
J7649_RS07480	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J7649_RS07485	COG0183	Belongs to the thiolase family
J7649_RS07490	COG1250	3-hydroxyacyl-CoA dehydrogenase
J7649_RS07495	COG1024	Enoyl-CoA hydratase
J7649_RS07500	COG1024	Enoyl-CoA hydratase
J7649_RS07505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J7649_RS07510	COG2151	metal-sulfur cluster biosynthetic enzyme
J7649_RS07515	COG3396	Phenylacetate-CoA oxygenase
J7649_RS07520	COG3460	Phenylacetate-CoA oxygenase
J7649_RS07525	COG3396	Phenylacetate-CoA oxygenase
J7649_RS07530	COG2030	dehydratase
J7649_RS07530	COG1012	belongs to the aldehyde dehydrogenase family
J7649_RS07535	COG2814	Major facilitator Superfamily
J7649_RS07545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J7649_RS07555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J7649_RS07570	COG4269	membrane
J7649_RS07590	COG1968	undecaprenyl-diphosphatase activity
J7649_RS07595	COG1214	PFAM Peptidase M22, glycoprotease
J7649_RS07605	COG0494	nUDIX hydrolase
J7649_RS07655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J7649_RS07660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J7649_RS07730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J7649_RS07735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J7649_RS07745	COG0653	protein targeting
J7649_RS07750	COG0450	alkyl hydroperoxide reductase
J7649_RS07765	COG0285	dihydrofolate synthase activity
J7649_RS07820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J7649_RS07830	COG1704	LemA family
J7649_RS07850	COG1862	Preprotein translocase
J7649_RS07860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J7649_RS07870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J7649_RS07900	COG2084	Dehydrogenase
J7649_RS07905	COG3622	Belongs to the hyi family
J7649_RS07930	COG2814	Major facilitator Superfamily
J7649_RS07940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J7649_RS07950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J7649_RS07955	COG2003	Belongs to the UPF0758 family
J7649_RS07960	COG3781	membrane
J7649_RS07975	COG2350	Protein conserved in bacteria
J7649_RS08005	COG1607	acyl-coa hydrolase
J7649_RS08070	COG1183	phosphatidylcholine synthase activity
J7649_RS08075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J7649_RS08115	COG1196	nuclear chromosome segregation
J7649_RS08115	COG0741	lytic transglycosylase activity
J7649_RS08115	COG0739	heme binding
J7649_RS08120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J7649_RS08125	COG1702	phosphate starvation-inducible protein PhoH
J7649_RS08180	COG1295	ribonuclease BN
J7649_RS08185	COG0697	spore germination
J7649_RS08200	COG0179	Fumarylacetoacetate (FAA) hydrolase
J7649_RS08240	COG0557	exoribonuclease II activity
J7649_RS08245	COG0339	signal peptide processing
J7649_RS08250	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J7649_RS08260	COG0697	spore germination
J7649_RS08285	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J7649_RS08290	COG1960	acyl-CoA dehydrogenase activity
J7649_RS08295	COG2072	flavoprotein involved in K transport
J7649_RS08300	COG0203	ribosomal protein L17
J7649_RS08305	COG0202	RNA polymerase activity
J7649_RS08310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J7649_RS08320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J7649_RS08345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J7649_RS08355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J7649_RS08360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J7649_RS08410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J7649_RS08420	COG0089	rRNA binding
J7649_RS08425	COG0088	Forms part of the polypeptide exit tunnel
J7649_RS08445	COG0626	cystathionine gamma-synthase activity
J7649_RS08450	COG0433	COG0433 Predicted ATPase
J7649_RS08455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J7649_RS08455	COG1017	nitric oxide dioxygenase activity
J7649_RS08460	COG1959	2 iron, 2 sulfur cluster binding
J7649_RS08470	COG1301	dicarboxylic acid transport
J7649_RS08475	COG1946	Acyl-CoA thioesterase
J7649_RS08480	COG2937	Belongs to the GPAT DAPAT family
J7649_RS08490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J7649_RS08495	COG1040	competence protein
J7649_RS08500	COG0494	nUDIX hydrolase
J7649_RS08510	COG0598	Magnesium transport protein CorA
J7649_RS08525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J7649_RS08530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J7649_RS08535	COG1127	ABC transporter
J7649_RS08540	COG0513	Belongs to the DEAD box helicase family
J7649_RS08560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J7649_RS08565	COG0408	coproporphyrinogen oxidase activity
J7649_RS08580	COG1960	acyl-CoA dehydrogenase activity
J7649_RS08585	COG1278	Cold shock
J7649_RS08600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J7649_RS08610	COG0534	Mate efflux family protein
J7649_RS08620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J7649_RS08625	COG0254	rRNA binding
J7649_RS08630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J7649_RS08665	COG0628	permease
J7649_RS08675	COG1289	transmembrane transporter activity
J7649_RS08680	COG2814	Major facilitator Superfamily
J7649_RS08705	COG0277	FAD linked oxidase domain protein
J7649_RS08710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J7649_RS08715	COG5006	permease, DMT superfamily
J7649_RS08740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J7649_RS08745	COG5380	lipid catabolic process
J7649_RS08750	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J7649_RS08755	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J7649_RS08760	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J7649_RS08765	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J7649_RS08770	COG0335	large ribosomal subunit rRNA binding
J7649_RS08780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J7649_RS08785	COG0228	four-way junction DNA binding
J7649_RS08820	COG4969	Belongs to the N-Me-Phe pilin family
J7649_RS08830	COG0194	GDP metabolic process
J7649_RS08835	COG1758	RNA polymerase activity
J7649_RS08840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J7649_RS08860	COG3307	-O-antigen
J7649_RS08885	COG1704	LemA family
J7649_RS08890	COG0493	'glutamate synthase
J7649_RS08895	COG0067	glutamate synthase
J7649_RS08895	COG0069	glutamate synthase activity
J7649_RS08895	COG0070	glutamate synthase
J7649_RS08945	COG2226	methyltransferase
J7649_RS08950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J7649_RS08955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J7649_RS08960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J7649_RS08980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J7649_RS08995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J7649_RS09015	COG0488	(ABC) transporter
J7649_RS09020	COG2873	o-acetylhomoserine
J7649_RS09025	COG4221	oxidoreductase activity
J7649_RS09030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J7649_RS09045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J7649_RS09045	COG2111	Na H antiporter
J7649_RS09050	COG1006	Multisubunit Na H antiporter MnhC subunit
J7649_RS09055	COG0651	ATP synthesis coupled electron transport
J7649_RS09060	COG1863	multisubunit Na H antiporter MnhE subunit
J7649_RS09065	COG2212	antiporter activity
J7649_RS09070	COG1320	monovalent cation:proton antiporter activity
J7649_RS09075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J7649_RS09085	COG0195	Participates in both transcription termination and antitermination
J7649_RS09090	COG0779	Required for maturation of 30S ribosomal subunits
J7649_RS09145	COG0237	dephospho-CoA kinase activity
J7649_RS09155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J7649_RS09160	COG3123	guanosine phosphorylase activity
J7649_RS09165	COG0497	DNA recombination
J7649_RS09190	COG2826	transposase and inactivated derivatives, IS30 family
J7649_RS09200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J7649_RS09210	COG1132	(ABC) transporter
J7649_RS09230	COG1538	Outer membrane efflux protein
J7649_RS09245	COG0494	nUDIX hydrolase
J7649_RS09250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J7649_RS09255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J7649_RS09260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J7649_RS09270	COG0772	Belongs to the SEDS family
J7649_RS09295	COG4974	Belongs to the 'phage' integrase family
J7649_RS09300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J7649_RS09310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J7649_RS09315	COG1686	Belongs to the peptidase S11 family
J7649_RS09320	COG2197	response regulator
J7649_RS09325	COG4191	Histidine kinase
J7649_RS09335	COG0793	Belongs to the peptidase S41A family
J7649_RS09335	COG3409	Peptidoglycan-binding domain 1 protein
J7649_RS09340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J7649_RS09345	COG0795	lipopolysaccharide-transporting ATPase activity
J7649_RS09350	COG0795	lipopolysaccharide-transporting ATPase activity
J7649_RS09370	COG0586	Pfam SNARE associated Golgi protein
J7649_RS09385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J7649_RS09385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J7649_RS09395	COG0004	ammonium transporteR
J7649_RS09400	COG0347	Belongs to the P(II) protein family
J7649_RS09410	COG0606	chelatase, subunit chli
J7649_RS09425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J7649_RS09440	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS09450	COG0477	Major facilitator Superfamily
J7649_RS09455	COG2860	membrane
J7649_RS09465	COG1253	flavin adenine dinucleotide binding
J7649_RS09500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J7649_RS09505	COG0477	Major facilitator Superfamily
J7649_RS09525	COG2814	Major facilitator Superfamily
J7649_RS09575	COG0758	DNA mediated transformation
J7649_RS09585	COG0697	spore germination
J7649_RS09590	COG0386	Belongs to the glutathione peroxidase family
J7649_RS09605	COG1012	belongs to the aldehyde dehydrogenase family
J7649_RS09625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J7649_RS09675	COG1121	(ABC) transporter
J7649_RS09680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J7649_RS09690	COG2837	iron assimilation
J7649_RS09700	COG3179	chitinase
J7649_RS09710	COG0436	Aminotransferase
J7649_RS09715	COG0534	Mate efflux family protein
J7649_RS09750	COG3706	GGDEF domain
J7649_RS09755	COG3706	GGDEF domain
J7649_RS09760	COG1715	Restriction endonuclease
J7649_RS09765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J7649_RS09765	COG0519	Catalyzes the synthesis of GMP from XMP
J7649_RS09770	COG0586	Pfam SNARE associated Golgi protein
J7649_RS09785	COG1192	Involved in chromosome partitioning
J7649_RS09795	COG0271	Belongs to the BolA IbaG family
J7649_RS09855	COG0281	malic enzyme
J7649_RS09875	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J7649_RS09885	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J7649_RS09890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J7649_RS09900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J7649_RS09945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J7649_RS09955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J7649_RS09970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J7649_RS09980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J7649_RS09985	COG1181	Belongs to the D-alanine--D-alanine ligase family
J7649_RS10000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J7649_RS10035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J7649_RS10055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J7649_RS10070	COG0463	Glycosyl transferase, family 2
J7649_RS10080	COG1216	Glycosyl transferase, family 2
J7649_RS10085	COG2244	polysaccharide biosynthetic process
J7649_RS10100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J7649_RS10110	COG1596	polysaccharide export
J7649_RS10145	COG0739	heme binding
J7649_RS10155	COG2818	Glycosylase
J7649_RS10160	COG1064	alcohol dehydrogenase
J7649_RS10195	COG0675	Transposase, IS605 OrfB family
J7649_RS10215	COG1309	transcriptional regulator
J7649_RS10225	COG2233	PERMEase
J7649_RS10245	COG0675	Transposase, IS605 OrfB family
J7649_RS10250	COG0129	dihydroxy-acid dehydratase activity
J7649_RS10255	COG0129	dihydroxy-acid dehydratase activity
J7649_RS10265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J7649_RS10270	COG0428	transporter
J7649_RS10280	COG0733	neurotransmitter:sodium symporter activity
J7649_RS10285	COG1012	belongs to the aldehyde dehydrogenase family
J7649_RS10295	COG0693	protein deglycase activity
J7649_RS10300	COG0666	response to abiotic stimulus
J7649_RS10310	COG2814	Major facilitator Superfamily
J7649_RS10315	COG2814	Major facilitator Superfamily
J7649_RS10345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J7649_RS10355	COG0657	acetylesterase activity
J7649_RS10410	COG0488	(ABC) transporter
J7649_RS10415	COG1063	alcohol dehydrogenase
J7649_RS10420	COG0187	DNA topoisomerase II activity
J7649_RS10430	COG0592	DNA-directed DNA polymerase activity
J7649_RS10435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J7649_RS10445	COG0594	ribonuclease P activity
J7649_RS10450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J7649_RS10455	COG0706	membrane insertase activity
J7649_RS10490	COG0402	S-adenosylhomocysteine deaminase activity
J7649_RS10500	COG0861	Integral membrane protein TerC family
J7649_RS10510	COG2388	GCN5-related N-acetyl-transferase
J7649_RS10535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J7649_RS10555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J7649_RS10560	COG2951	lytic endotransglycosylase activity
J7649_RS10565	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J7649_RS10570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J7649_RS10605	COG2133	pyrroloquinoline quinone binding
J7649_RS10620	COG1047	Peptidyl-prolyl cis-trans
J7649_RS10625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J7649_RS10630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J7649_RS10635	COG0196	riboflavin kinase activity
J7649_RS10645	COG1309	transcriptional regulator
J7649_RS10650	COG1116	anion transmembrane transporter activity
J7649_RS10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7649_RS10660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7649_RS10665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J7649_RS10670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J7649_RS10675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J7649_RS10675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J7649_RS10700	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS10705	COG0546	phosphoglycolate phosphatase activity
J7649_RS10710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J7649_RS10715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J7649_RS10725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J7649_RS10740	COG3023	N-Acetylmuramoyl-L-alanine amidase
J7649_RS10745	COG0728	peptidoglycan biosynthetic process
J7649_RS10750	COG5487	UPF0391 membrane protein
J7649_RS10755	COG2983	Belongs to the UPF0260 family
J7649_RS10760	COG3300	MHYT domain
J7649_RS10760	COG5001	Diguanylate cyclase
J7649_RS10765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J7649_RS10770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J7649_RS10780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J7649_RS10785	COG2814	Major facilitator Superfamily
J7649_RS10790	COG1335	isochorismatase
J7649_RS10795	COG0385	Bile acid
J7649_RS10830	COG0753	catalase activity
J7649_RS10875	COG2733	membrane
J7649_RS10890	COG2918	glutathione biosynthetic process
J7649_RS10895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J7649_RS10905	COG3150	esterase
J7649_RS10925	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7649_RS10950	COG1247	-acetyltransferase
J7649_RS10955	COG3248	Nucleoside-binding outer membrane protein
J7649_RS10980	COG3706	GGDEF domain
J7649_RS10985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J7649_RS11005	COG0708	Exodeoxyribonuclease III
J7649_RS11010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J7649_RS11025	COG1278	Cold shock
J7649_RS11040	COG2132	Multicopper oxidase
J7649_RS11055	COG0189	ligase activity
J7649_RS11070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J7649_RS11080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J7649_RS11090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J7649_RS11115	COG0508	dehydrogenase complex catalyzes the overall conversion of
J7649_RS11120	COG2119	membrane
J7649_RS11125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J7649_RS11125	COG0426	domain, Protein
J7649_RS11150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J7649_RS11175	COG1902	pentaerythritol trinitrate reductase activity
J7649_RS11180	COG1519	Transferase
J7649_RS11185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J7649_RS11190	COG0668	transmembrane transport
J7649_RS11195	COG3152	Membrane
J7649_RS11200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J7649_RS11210	COG0415	Belongs to the DNA photolyase family
J7649_RS11215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J7649_RS11220	COG0431	NADPH-dependent FMN reductase
J7649_RS11235	COG0784	Response regulator, receiver
J7649_RS11235	COG2205	protein histidine kinase activity
J7649_RS11240	COG3162	membrane
J7649_RS11245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J7649_RS11255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J7649_RS11270	COG3706	GGDEF domain
J7649_RS11290	COG0351	phosphomethylpyrimidine kinase
J7649_RS11290	COG0352	thiamine-phosphate diphosphorylase activity
J7649_RS11290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J7649_RS11300	COG2814	Major facilitator Superfamily
J7649_RS11315	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
J7649_RS11340	COG3158	transport of potassium into the cell
J7649_RS11375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J7649_RS11410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J7649_RS11475	COG1250	3-hydroxyacyl-CoA dehydrogenase
J7649_RS11475	COG1024	Enoyl-CoA hydratase
J7649_RS11500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J7649_RS11520	COG3275	phosphorelay sensor kinase activity
J7649_RS11530	COG0181	hydroxymethylbilane synthase activity
J7649_RS11550	COG0824	Thioesterase
J7649_RS11580	COG0546	phosphoglycolate phosphatase activity
J7649_RS11610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J7649_RS11635	COG0081	regulation of translation
J7649_RS11640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J7649_RS11645	COG0222	ribosome binding
J7649_RS11650	COG0085	RNA polymerase activity
J7649_RS11655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J7649_RS11675	COG2056	Na+-H+ antiporter family
J7649_RS11680	COG3047	cAMP biosynthetic process
J7649_RS11690	COG0326	Molecular chaperone. Has ATPase activity
J7649_RS11725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J7649_RS11730	COG0427	acetyl-CoA hydrolase
J7649_RS11760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J7649_RS11790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J7649_RS11795	COG1074	ATP-dependent DNA helicase activity
J7649_RS11800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J7649_RS11805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J7649_RS11810	COG1185	polyribonucleotide nucleotidyltransferase activity
J7649_RS11815	COG0598	Magnesium transport protein CorA
J7649_RS11820	COG2841	Protein conserved in bacteria
J7649_RS11825	COG0789	Transcriptional regulator
J7649_RS11835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J7649_RS11840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J7649_RS11840	COG0475	glutathione-regulated potassium exporter activity
J7649_RS11845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J7649_RS11870	COG4535	Mg2 and Co2 transporter CorC
J7649_RS11875	COG0425	Belongs to the sulfur carrier protein TusA family
J7649_RS11880	COG0644	oxidoreductase
J7649_RS11880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J7649_RS11890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J7649_RS11905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J7649_RS11910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J7649_RS11920	COG0493	'glutamate synthase
J7649_RS11945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J7649_RS11965	COG0751	glycine-tRNA ligase activity
J7649_RS11985	COG0471	metal ion transport
J7649_RS11995	COG1983	PspC domain protein
J7649_RS12020	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS12025	COG1530	ribonuclease E activity
J7649_RS12030	COG0564	pseudouridine synthase activity
J7649_RS12040	COG0546	phosphoglycolate phosphatase activity
J7649_RS12045	COG3971	2-oxopent-4-enoate hydratase activity
J7649_RS12050	COG4569	acetaldehyde dehydrogenase (acetylating) activity
J7649_RS12075	COG0583	DNA-binding transcription factor activity
J7649_RS12080	COG4638	Rieske (2fe-2S)
J7649_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
J7649_RS12100	COG3384	dioxygenase
J7649_RS12105	COG0446	pyridine nucleotide-disulphide oxidoreductase
J7649_RS12130	COG3011	Protein conserved in bacteria
J7649_RS12135	COG0753	catalase activity
J7649_RS12175	COG0583	DNA-binding transcription factor activity
J7649_RS12185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J7649_RS12200	COG0473	3-isopropylmalate dehydrogenase activity
J7649_RS12255	COG1560	Kdo2-lipid A biosynthetic process
J7649_RS12260	COG0488	(ABC) transporter
J7649_RS12265	COG2900	Belongs to the SlyX family
J7649_RS12295	COG1929	Belongs to the glycerate kinase type-1 family
J7649_RS12300	COG0210	DNA helicase
J7649_RS12320	COG4651	solute:proton antiporter activity
J7649_RS12320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J7649_RS12345	COG0788	formyltetrahydrofolate deformylase activity
J7649_RS12390	COG3040	lipid binding
J7649_RS12430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J7649_RS12445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J7649_RS12455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J7649_RS12455	COG2813	Specifically methylates the guanine in position
J7649_RS12460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J7649_RS12465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J7649_RS12475	COG4774	siderophore transport
J7649_RS12480	COG4771	TonB-dependent receptor
J7649_RS12490	COG0740	serine-type endopeptidase activity
J7649_RS12505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J7649_RS12505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J7649_RS12515	COG0857	belongs to the CobB CobQ family
J7649_RS12515	COG0280	phosphate acetyltransferase
J7649_RS12520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J7649_RS12545	COG0793	Belongs to the peptidase S41A family
J7649_RS12555	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J7649_RS12570	COG0084	hydrolase, TatD family'
J7649_RS12585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J7649_RS12595	COG1162	GTPase activity
J7649_RS12600	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J7649_RS12610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J7649_RS12620	COG1538	Outer membrane efflux protein
J7649_RS12625	COG0577	efflux transmembrane transporter activity
J7649_RS12625	COG1136	(ABC) transporter
J7649_RS12630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J7649_RS12655	COG0028	Belongs to the TPP enzyme family
J7649_RS12660	COG0440	acetolactate synthase activity
J7649_RS12665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J7649_RS12705	COG2975	iron-sulfur cluster assembly
J7649_RS12725	COG1426	Protein conserved in bacteria
J7649_RS12735	COG0124	histidyl-tRNA synthetase
J7649_RS12745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J7649_RS12760	COG0300	oxidoreductase activity
J7649_RS12765	COG3956	TIGRFAM MazG family protein
J7649_RS12770	COG1555	photosystem II stabilization
J7649_RS12775	COG0617	tRNA 3'-terminal CCA addition
J7649_RS12780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J7649_RS12795	COG1660	Displays ATPase and GTPase activities
J7649_RS12810	COG2205	protein histidine kinase activity
J7649_RS12815	COG0675	Transposase, IS605 OrfB family
J7649_RS12820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J7649_RS12835	COG0463	Glycosyl transferase, family 2
J7649_RS12860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J7649_RS12905	COG1960	acyl-CoA dehydrogenase activity
J7649_RS12910	COG1960	acyl-CoA dehydrogenase activity
J7649_RS12920	COG2205	protein histidine kinase activity
J7649_RS12925	COG0745	RESPONSE REGULATOR receiver
J7649_RS12930	COG3153	acetyltransferase
J7649_RS12935	COG2315	Protein conserved in bacteria
J7649_RS12940	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J7649_RS12955	COG2096	Adenosyltransferase
J7649_RS12960	COG4206	TonB-dependent receptor
J7649_RS12975	COG0318	PFAM AMP-dependent synthetase and ligase
J7649_RS12995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J7649_RS13010	COG0625	glutathione transferase activity
J7649_RS13020	COG1238	metal cluster binding
J7649_RS13050	COG0072	phenylalanine-tRNA ligase activity
J7649_RS13075	COG0248	Ppx GppA phosphatase
J7649_RS13085	COG0037	tRNA processing
J7649_RS13130	COG1764	response to oxidative stress
J7649_RS13135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J7649_RS13185	COG2969	positive regulation of protein catabolic process
J7649_RS13190	COG0625	glutathione transferase activity
J7649_RS13195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J7649_RS13200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J7649_RS13205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J7649_RS13210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J7649_RS13215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J7649_RS13250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J7649_RS13260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J7649_RS13265	COG1408	metallophosphoesterase
J7649_RS13275	COG0477	Major facilitator Superfamily
J7649_RS13280	COG1272	protein, Hemolysin III
J7649_RS13300	COG1250	3-hydroxyacyl-CoA dehydrogenase
J7649_RS13300	COG1024	Enoyl-CoA hydratase
J7649_RS13305	COG0183	Belongs to the thiolase family
J7649_RS13310	COG2207	Transcriptional regulator
J7649_RS13315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J7649_RS13320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J7649_RS13335	COG0183	Belongs to the thiolase family
J7649_RS13355	COG0833	amino acid
J7649_RS13365	COG2233	PERMEase
J7649_RS13370	COG1217	gtp-binding protein TYPA
J7649_RS13395	COG1902	pentaerythritol trinitrate reductase activity
J7649_RS13415	COG0354	folic acid binding
J7649_RS13420	COG2132	Multicopper oxidase
J7649_RS13465	COG0564	pseudouridine synthase activity
J7649_RS13485	COG2824	Alkylphosphonate utilization operon protein PhnA
J7649_RS13500	COG0628	permease
J7649_RS13510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J7649_RS13510	COG0352	thiamine-phosphate diphosphorylase activity
J7649_RS13510	COG0351	phosphomethylpyrimidine kinase
J7649_RS13525	COG3152	Membrane
J7649_RS13540	COG4772	TonB-dependent receptor
J7649_RS13545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J7649_RS13560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J7649_RS13560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J7649_RS13565	COG0745	RESPONSE REGULATOR receiver
J7649_RS13570	COG2205	protein histidine kinase activity
J7649_RS13585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7649_RS13605	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J7649_RS13620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7649_RS13630	COG0713	ATP synthesis coupled electron transport
J7649_RS13635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J7649_RS13640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J7649_RS13670	COG0583	DNA-binding transcription factor activity
J7649_RS13680	COG1126	abc transporter atp-binding protein
J7649_RS13685	COG0765	amino acid transport
J7649_RS13690	COG0765	amino acid transport
J7649_RS13705	COG0531	amino acid
J7649_RS13710	COG4303	Ethanolamine ammonia lyase large subunit
J7649_RS13725	COG0668	transmembrane transport
J7649_RS13740	COG2081	HI0933 family
J7649_RS13750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J7649_RS13765	COG0004	ammonium transporteR
J7649_RS13770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J7649_RS13785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J7649_RS13785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J7649_RS13795	COG0489	protein tyrosine kinase activity
J7649_RS13840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J7649_RS13865	COG0840	transmembrane signaling receptor activity
J7649_RS13870	COG0643	Histidine kinase
J7649_RS13870	COG2198	Histidine kinase
J7649_RS13870	COG0784	Response regulator, receiver
J7649_RS13895	COG2832	Protein of unknown function (DUF454)
J7649_RS13955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J7649_RS13965	COG1289	transmembrane transporter activity
J7649_RS13970	COG2814	Major facilitator Superfamily
J7649_RS13980	COG0786	glutamate:sodium symporter activity
J7649_RS13985	COG1115	amino acid carrier protein
J7649_RS13990	COG2059	Chromate
J7649_RS13995	COG1752	Esterase of the alpha-beta hydrolase superfamily
J7649_RS14005	COG1607	acyl-coa hydrolase
J7649_RS14015	COG2814	Major facilitator Superfamily
J7649_RS14020	COG0583	DNA-binding transcription factor activity
J7649_RS14040	COG0523	cobalamin synthesis protein
J7649_RS14045	COG4681	YaeQ
J7649_RS14060	COG5001	Diguanylate cyclase
J7649_RS14060	COG4251	negative regulation of phosphorylation
J7649_RS14060	COG3706	GGDEF domain
J7649_RS14060	COG2203	Gaf domain
J7649_RS14090	COG0393	Putative heavy-metal-binding
J7649_RS14095	COG0393	Putative heavy-metal-binding
J7649_RS14110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J7649_RS14115	COG0671	phosphoesterase, PA-phosphatase related
J7649_RS14130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J7649_RS14140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J7649_RS14150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J7649_RS14155	COG1648	precorrin-2 dehydrogenase activity
J7649_RS14155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J7649_RS14160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J7649_RS14170	COG0531	amino acid
J7649_RS14185	COG0321	lipoyl(octanoyl) transferase activity
J7649_RS14190	COG2921	Belongs to the UPF0250 family
J7649_RS14215	COG0586	Pfam SNARE associated Golgi protein
J7649_RS14260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J7649_RS14265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J7649_RS14295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J7649_RS14375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J7649_RS14410	COG3421	Type III restriction
J7649_RS14415	COG2189	Belongs to the N(4) N(6)-methyltransferase family
J7649_RS14425	COG1525	nuclease
J7649_RS14475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J7649_RS14640	COG2826	transposase and inactivated derivatives, IS30 family
J7649_RS14650	COG2826	transposase and inactivated derivatives, IS30 family
J7649_RS14720	COG1132	(ABC) transporter
J7649_RS14770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J7649_RS14790	COG3293	Transposase
J7649_RS14835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J7649_RS14845	COG1683	Conserved Protein
J7649_RS15025	COG1475	DNA binding
J7649_RS15030	COG1192	Involved in chromosome partitioning
J7649_RS15335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J7649_RS15390	COG3173	Aminoglycoside phosphotransferase
J7649_RS15395	COG0488	(ABC) transporter
J7649_RS15410	COG2801	Transposase and inactivated derivatives
J7649_RS15420	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J7649_RS15425	COG3657	addiction module killer protein
J7649_RS15430	COG2801	Transposase and inactivated derivatives
J7649_RS15455	COG2963	transposase activity
J7649_RS15485	COG0860	N-Acetylmuramoyl-L-alanine amidase
J7649_RS15515	COG0604	alcohol dehydrogenase
J7649_RS15515	COG3321	synthase
J7649_RS15560	COG1192	Involved in chromosome partitioning
J7649_RS15570	COG3293	Transposase
J7649_RS15620	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
J7649_RS15630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J7649_RS15635	COG1335	isochorismatase
J7649_RS15655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J7649_RS15680	COG1454	alcohol dehydrogenase
J7649_RS15705	COG4773	Receptor
J7649_RS15730	COG2267	carboxylic ester hydrolase activity
J7649_RS15730	COG2226	methyltransferase
J7649_RS15745	COG4106	trans-aconitate 2-methyltransferase activity
J7649_RS15755	COG0642	Histidine kinase
J7649_RS15770	COG2186	Transcriptional regulator
J7649_RS15785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J7649_RS15785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J7649_RS15790	COG1105	Belongs to the carbohydrate kinase PfkB family
J7649_RS15795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J7649_RS15795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J7649_RS15795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J7649_RS15820	COG0475	glutathione-regulated potassium exporter activity
J7649_RS15820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J7649_RS15840	COG1309	transcriptional regulator
J7649_RS15845	COG0604	alcohol dehydrogenase
J7649_RS15865	COG2801	Transposase and inactivated derivatives
J7649_RS15920	COG0730	response to heat
J7649_RS15925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J7649_RS15930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J7649_RS15955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J7649_RS15995	COG0579	oxidoreductase
J7649_RS16020	COG2130	NADP-dependent
J7649_RS16025	COG1309	transcriptional regulator
J7649_RS16035	COG1902	pentaerythritol trinitrate reductase activity
J7649_RS16045	COG1979	alcohol dehydrogenase
J7649_RS16055	COG2801	Transposase and inactivated derivatives
J7649_RS16080	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
J7649_RS16095	COG3077	Addiction module antitoxin, RelB DinJ family
J7649_RS16100	COG2801	Transposase and inactivated derivatives
J7649_RS16115	COG2132	Multicopper oxidase
J7649_RS16175	COG2072	flavoprotein involved in K transport
J7649_RS16180	COG0431	NADPH-dependent FMN reductase
J7649_RS16185	COG0798	PFAM Bile acid sodium symporter
J7649_RS16195	COG0640	Transcriptional regulator
J7649_RS16205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J7649_RS16210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J7649_RS16255	COG2217	Heavy metal translocating P-type atpase
J7649_RS16260	COG3174	membrane
J7649_RS16265	COG2205	protein histidine kinase activity
J7649_RS16280	COG2132	Multicopper oxidase
J7649_RS16300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J7649_RS16305	COG1846	Transcriptional regulator
J7649_RS16310	COG1764	response to oxidative stress
J7649_RS16350	COG1192	Involved in chromosome partitioning
J7649_RS16430	COG3293	Transposase
J7649_RS16455	COG3504	Conjugal transfer protein
J7649_RS16480	COG0739	heme binding
J7649_RS16480	COG1196	nuclear chromosome segregation
J7649_RS16480	COG0741	lytic transglycosylase activity
J7649_RS16495	COG1196	nuclear chromosome segregation
J7649_RS16495	COG0741	lytic transglycosylase activity
J7649_RS16495	COG0739	heme binding
J7649_RS16505	COG3451	type IV secretory pathway VirB4
J7649_RS16565	COG2826	transposase and inactivated derivatives, IS30 family
J7649_RS16570	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J7649_RS16580	COG2826	transposase and inactivated derivatives, IS30 family
J7649_RS16615	COG4227	nucleotidyltransferase activity
J7649_RS16640	COG1192	Involved in chromosome partitioning
J7649_RS16650	COG3293	Transposase
J7649_RS16680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J7649_RS16685	COG0659	secondary active sulfate transmembrane transporter activity