locus-tag	class	description
DKE47_RS00010	COG0592	DNA-directed DNA polymerase activity
DKE47_RS00030	COG0586	Pfam SNARE associated Golgi protein
DKE47_RS00060	COG0596	Alpha beta hydrolase
DKE47_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKE47_RS00110	COG0733	neurotransmitter:sodium symporter activity
DKE47_RS00150	COG2233	PERMEase
DKE47_RS00205	COG0656	L-ascorbic acid biosynthetic process
DKE47_RS00210	COG0583	DNA-binding transcription factor activity
DKE47_RS00230	COG1064	alcohol dehydrogenase
DKE47_RS00235	COG2818	Glycosylase
DKE47_RS00250	COG1194	a g-specific adenine glycosylase
DKE47_RS00265	COG5487	UPF0391 membrane protein
DKE47_RS00270	COG2983	Belongs to the UPF0260 family
DKE47_RS00275	COG2133	pyrroloquinoline quinone binding
DKE47_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE47_RS00315	COG0385	Bile acid
DKE47_RS00355	COG1113	amino acid transport
DKE47_RS00365	COG0523	cobalamin synthesis protein
DKE47_RS00375	COG2188	Transcriptional regulator
DKE47_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKE47_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKE47_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DKE47_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DKE47_RS00545	COG0436	Aminotransferase
DKE47_RS00550	COG2733	membrane
DKE47_RS00565	COG2918	glutathione biosynthetic process
DKE47_RS00650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE47_RS00660	COG2233	PERMEase
DKE47_RS00665	COG2351	hydroxyisourate hydrolase activity
DKE47_RS00720	COG0708	Exodeoxyribonuclease III
DKE47_RS00765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKE47_RS00810	COG2119	membrane
DKE47_RS00860	COG1902	pentaerythritol trinitrate reductase activity
DKE47_RS00895	COG1522	sequence-specific DNA binding
DKE47_RS00925	COG3162	membrane
DKE47_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE47_RS00970	COG1309	transcriptional regulator
DKE47_RS00990	COG0351	phosphomethylpyrimidine kinase
DKE47_RS00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE47_RS00990	COG0352	thiamine-phosphate diphosphorylase activity
DKE47_RS01000	COG2814	Major facilitator Superfamily
DKE47_RS01075	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_RS01085	COG1335	isochorismatase
DKE47_RS01120	COG2814	Major facilitator Superfamily
DKE47_RS01125	COG0583	DNA-binding transcription factor activity
DKE47_RS01165	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_RS01310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKE47_RS01375	COG4221	oxidoreductase activity
DKE47_RS01380	COG2873	o-acetylhomoserine
DKE47_RS01385	COG0028	Belongs to the TPP enzyme family
DKE47_RS01455	COG0833	amino acid
DKE47_RS01505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKE47_RS01585	COG1704	LemA family
DKE47_RS01590	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DKE47_RS01655	COG0194	GDP metabolic process
DKE47_RS01705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKE47_RS01725	COG5380	lipid catabolic process
DKE47_RS01745	COG5006	permease, DMT superfamily
DKE47_RS01775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DKE47_RS01780	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE47_RS01810	COG0628	permease
DKE47_RS01960	COG0517	IMP dehydrogenase activity
DKE47_RS01965	COG1983	PspC domain protein
DKE47_RS01990	COG0408	coproporphyrinogen oxidase activity
DKE47_RS02015	COG1127	ABC transporter
DKE47_RS02020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DKE47_RS02030	COG2854	intermembrane phospholipid transfer
DKE47_RS02050	COG0494	nUDIX hydrolase
DKE47_RS02055	COG1040	competence protein
DKE47_RS02080	COG1946	Acyl-CoA thioesterase
DKE47_RS02100	COG1959	2 iron, 2 sulfur cluster binding
DKE47_RS02105	COG1017	nitric oxide dioxygenase activity
DKE47_RS02105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE47_RS02130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKE47_RS02135	COG0088	Forms part of the polypeptide exit tunnel
DKE47_RS02270	COG1960	acyl-CoA dehydrogenase activity
DKE47_RS02275	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DKE47_RS02305	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DKE47_RS02315	COG0557	exoribonuclease II activity
DKE47_RS02360	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKE47_RS02365	COG2207	Transcriptional regulator
DKE47_RS02375	COG1295	ribonuclease BN
DKE47_RS02410	COG1702	phosphate starvation-inducible protein PhoH
DKE47_RS02450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DKE47_RS02455	COG1183	phosphatidylcholine synthase activity
DKE47_RS02570	COG2969	positive regulation of protein catabolic process
DKE47_RS02580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKE47_RS02585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKE47_RS02595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKE47_RS02600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKE47_RS02635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE47_RS02710	COG1607	acyl-coa hydrolase
DKE47_RS02745	COG2350	Protein conserved in bacteria
DKE47_RS02760	COG3781	membrane
DKE47_RS02775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKE47_RS02785	COG1862	Preprotein translocase
DKE47_RS02860	COG3646	Phage regulatory protein
DKE47_RS02900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE47_RS03055	COG2205	protein histidine kinase activity
DKE47_RS03055	COG2198	Histidine kinase
DKE47_RS03055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE47_RS03055	COG0784	Response regulator, receiver
DKE47_RS03075	COG2194	sulfuric ester hydrolase activity
DKE47_RS03170	COG1960	acyl-CoA dehydrogenase activity
DKE47_RS03190	COG0745	RESPONSE REGULATOR receiver
DKE47_RS03195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DKE47_RS03270	COG0285	dihydrofolate synthase activity
DKE47_RS03305	COG0477	Major facilitator Superfamily
DKE47_RS03320	COG2153	protein acetylation
DKE47_RS03345	COG2207	Transcriptional regulator
DKE47_RS03395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DKE47_RS03395	COG2885	chlorophyll binding
DKE47_RS03405	COG1690	Belongs to the RtcB family
DKE47_RS03410	COG0833	amino acid
DKE47_RS03425	COG1217	gtp-binding protein TYPA
DKE47_RS03450	COG2094	Belongs to the DNA glycosylase MPG family
DKE47_RS03455	COG4772	TonB-dependent receptor
DKE47_RS03495	COG3189	MarR family transcriptional regulator
DKE47_RS03500	COG2824	Alkylphosphonate utilization operon protein PhnA
DKE47_RS03545	COG0840	transmembrane signaling receptor activity
DKE47_RS03575	COG2832	Protein of unknown function (DUF454)
DKE47_RS03580	COG1376	ErfK ybiS ycfS ynhG family protein
DKE47_RS03660	COG1115	amino acid carrier protein
DKE47_RS03670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKE47_RS03705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE47_RS03715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE47_RS03720	COG1077	Cell shape determining protein MreB Mrl
DKE47_RS03725	COG1792	Involved in formation and maintenance of cell shape
DKE47_RS03730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DKE47_RS03735	COG0424	maF-like protein
DKE47_RS03740	COG1530	ribonuclease E activity
DKE47_RS03770	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE47_RS03795	COG2207	Transcriptional regulator
DKE47_RS03845	COG0142	geranyltranstransferase activity
DKE47_RS03850	COG2315	Protein conserved in bacteria
DKE47_RS03895	COG0745	RESPONSE REGULATOR receiver
DKE47_RS03900	COG0642	Histidine kinase
DKE47_RS03940	COG0525	valine-tRNA ligase activity
DKE47_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS03970	COG0393	Putative heavy-metal-binding
DKE47_RS03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE47_RS04025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DKE47_RS04045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKE47_RS04080	COG2921	Belongs to the UPF0250 family
DKE47_RS04120	COG2009	succinate dehydrogenase
DKE47_RS04125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DKE47_RS04130	COG1053	succinate dehydrogenase
DKE47_RS04135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DKE47_RS04185	COG2321	neutral zinc metallopeptidase
DKE47_RS04215	COG0589	response to stress
DKE47_RS04235	COG0505	Belongs to the CarA family
DKE47_RS04260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKE47_RS04335	COG1597	lipid kinase activity
DKE47_RS04340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DKE47_RS04360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_RS04365	COG0584	glycerophosphoryl diester phosphodiesterase
DKE47_RS04385	COG0741	lytic transglycosylase activity
DKE47_RS04415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DKE47_RS04495	COG1024	Enoyl-CoA hydratase
DKE47_RS04505	COG0183	Belongs to the thiolase family
DKE47_RS04510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DKE47_RS04580	COG3811	Belongs to the UPF0386 family
DKE47_RS04665	COG0596	Alpha beta hydrolase
DKE47_RS04665	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE47_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS04680	COG0583	DNA-binding transcription factor activity
DKE47_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_RS04710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE47_RS04715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKE47_RS04720	COG0778	Nitroreductase
DKE47_RS04745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DKE47_RS04750	COG3339	Conserved Protein
DKE47_RS04805	COG1280	lysine exporter protein (LysE YggA)
DKE47_RS04810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DKE47_RS04910	COG4591	ABC-type transport system involved in lipoprotein release permease component
DKE47_RS04915	COG1136	(ABC) transporter
DKE47_RS04930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DKE47_RS04930	COG0616	signal peptide processing
DKE47_RS04940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DKE47_RS04950	COG0628	permease
DKE47_RS05025	COG0824	Thioesterase
DKE47_RS05055	COG2814	Major facilitator Superfamily
DKE47_RS05070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKE47_RS05075	COG1024	Enoyl-CoA hydratase
DKE47_RS05080	COG1051	belongs to the nudix hydrolase family
DKE47_RS05080	COG1056	cytidyltransferase-related domain
DKE47_RS05095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DKE47_RS05110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DKE47_RS05125	COG4625	pathogenesis
DKE47_RS05145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DKE47_RS05160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKE47_RS05225	COG1381	Involved in DNA repair and RecF pathway recombination
DKE47_RS05230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DKE47_RS05240	COG4221	oxidoreductase activity
DKE47_RS05375	COG1215	transferase activity, transferring glycosyl groups
DKE47_RS05400	COG1252	NADH dehydrogenase
DKE47_RS05405	COG1686	Belongs to the peptidase S11 family
DKE47_RS05420	COG1187	pseudouridine synthase activity
DKE47_RS05490	COG0352	thiamine-phosphate diphosphorylase activity
DKE47_RS05565	COG1522	sequence-specific DNA binding
DKE47_RS05580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKE47_RS05615	COG3647	Membrane
DKE47_RS05640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DKE47_RS05645	COG1686	Belongs to the peptidase S11 family
DKE47_RS05905	COG0582	viral genome integration into host DNA
DKE47_RS05920	COG0583	DNA-binding transcription factor activity
DKE47_RS05965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKE47_RS05975	COG2879	small protein
DKE47_RS06020	COG1741	Belongs to the pirin family
DKE47_RS06040	COG3739	integral membrane protein
DKE47_RS06065	COG0302	gtp cyclohydrolase
DKE47_RS06110	COG0512	Glutamine amidotransferase of anthranilate synthase
DKE47_RS06420	COG0174	glutamine synthetase
DKE47_RS06430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DKE47_RS06465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKE47_RS06495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKE47_RS06500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKE47_RS06525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE47_RS06530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE47_RS06550	COG0024	Methionine aminopeptidase
DKE47_RS06595	COG2951	lytic endotransglycosylase activity
DKE47_RS06615	COG0842	Transport permease protein
DKE47_RS06620	COG1131	(ABC) transporter
DKE47_RS06715	COG4215	(ABC) transporter
DKE47_RS06735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE47_RS06740	COG0826	peptidase U32
DKE47_RS06750	COG0384	phenazine biosynthesis protein PhzF
DKE47_RS06760	COG1720	tRNA m6t6A37 methyltransferase activity
DKE47_RS06775	COG3111	PFAM Bacterial OB fold (BOF) protein
DKE47_RS06810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKE47_RS06815	COG3139	Protein of unknown function (DUF1315)
DKE47_RS06835	COG1960	acyl-CoA dehydrogenase activity
DKE47_RS06855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DKE47_RS06875	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKE47_RS06935	COG0778	Nitroreductase
DKE47_RS06995	COG1610	YqeY-like protein
DKE47_RS07050	COG2831	hemolysin activation secretion protein
DKE47_RS07080	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DKE47_RS07170	COG2226	methyltransferase
DKE47_RS07285	COG1073	alpha beta
DKE47_RS07305	COG0583	DNA-binding transcription factor activity
DKE47_RS07310	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS07360	COG3008	intermembrane lipid transfer
DKE47_RS07360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DKE47_RS07370	COG2351	hydroxyisourate hydrolase activity
DKE47_RS07425	COG0642	Histidine kinase
DKE47_RS07465	COG0625	glutathione transferase activity
DKE47_RS07510	COG2011	ABC-type metal ion transport system permease component
DKE47_RS07535	COG0138	bifunctional purine biosynthesis protein purh
DKE47_RS07540	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DKE47_RS07580	COG1305	Transglutaminase-like
DKE47_RS07620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DKE47_RS07665	COG1215	transferase activity, transferring glycosyl groups
DKE47_RS07670	COG3658	cytochrome
DKE47_RS07680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE47_RS07720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKE47_RS07725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKE47_RS07750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE47_RS07780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DKE47_RS07785	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DKE47_RS07850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKE47_RS07855	COG2814	Major facilitator Superfamily
DKE47_RS07865	COG0583	DNA-binding transcription factor activity
DKE47_RS07900	COG0802	atpase or kinase
DKE47_RS07915	COG1923	regulation of RNA biosynthetic process
DKE47_RS07920	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_RS07955	COG0519	Catalyzes the synthesis of GMP from XMP
DKE47_RS07955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE47_RS07970	COG0531	amino acid
DKE47_RS07990	COG1454	alcohol dehydrogenase
DKE47_RS08065	COG1605	Chorismate mutase
DKE47_RS08115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE47_RS08120	COG0668	transmembrane transport
DKE47_RS08175	COG0589	response to stress
DKE47_RS08205	COG1522	sequence-specific DNA binding
DKE47_RS08220	COG0583	DNA-binding transcription factor activity
DKE47_RS08230	COG0183	Belongs to the thiolase family
DKE47_RS08240	COG2030	dehydratase
DKE47_RS08245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DKE47_RS08280	COG0824	Thioesterase
DKE47_RS08295	COG1335	isochorismatase
DKE47_RS08410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DKE47_RS08595	COG3755	Protein conserved in bacteria
DKE47_RS08765	COG0592	DNA-directed DNA polymerase activity
DKE47_RS08835	COG3293	Transposase
DKE47_RS08875	COG0511	ligase activity, forming carbon-carbon bonds
DKE47_RS08900	COG0745	RESPONSE REGULATOR receiver
DKE47_RS08940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DKE47_RS08955	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKE47_RS08955	COG0315	cyclic pyranopterin monophosphate synthase activity
DKE47_RS08995	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DKE47_RS09060	COG2204	response regulator
DKE47_RS09095	COG0575	Belongs to the CDS family
DKE47_RS09130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKE47_RS09145	COG2137	regulation of response to DNA damage stimulus
DKE47_RS09180	COG1522	sequence-specific DNA binding
DKE47_RS09190	COG1113	amino acid transport
DKE47_RS09215	COG2135	peptidase activity
DKE47_RS09255	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DKE47_RS09255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE47_RS09255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE47_RS09260	COG1105	Belongs to the carbohydrate kinase PfkB family
DKE47_RS09295	COG0024	Methionine aminopeptidase
DKE47_RS09310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DKE47_RS09315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE47_RS09320	COG0517	IMP dehydrogenase activity
DKE47_RS09320	COG0516	GMP reductase activity
DKE47_RS09350	COG0552	protein localization to endoplasmic reticulum
DKE47_RS09360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DKE47_RS09375	COG4890	Cyd operon protein YbgT
DKE47_RS09380	COG1294	oxidase, subunit
DKE47_RS09405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKE47_RS09435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKE47_RS09465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DKE47_RS09535	COG2323	membrane
DKE47_RS09545	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKE47_RS09570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DKE47_RS09580	COG2271	Major facilitator Superfamily
DKE47_RS09585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKE47_RS09595	COG3485	protocatechuate 3,4-dioxygenase
DKE47_RS09640	COG1414	Transcriptional regulator
DKE47_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS09735	COG3733	amine oxidase
DKE47_RS09745	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_RS09750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKE47_RS09755	COG0183	Belongs to the thiolase family
DKE47_RS09780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE47_RS09785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE47_RS09795	COG4829	muconolactone delta-isomerase
DKE47_RS09815	COG2186	Transcriptional regulator
DKE47_RS09860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DKE47_RS09870	COG0789	Transcriptional regulator
DKE47_RS10010	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_RS10040	COG2084	Dehydrogenase
DKE47_RS10070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE47_RS10095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE47_RS10240	COG2205	protein histidine kinase activity
DKE47_RS10250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE47_RS10280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKE47_RS10360	COG3539	Fimbrial protein
DKE47_RS10410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE47_RS10490	COG1535	isochorismatase
DKE47_RS10490	COG3433	isochorismatase activity
DKE47_RS10560	COG0725	ABC transporter, periplasmic molybdate-binding protein
DKE47_RS10575	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DKE47_RS10580	COG0543	2 iron, 2 sulfur cluster binding
DKE47_RS10580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE47_RS10595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE47_RS10635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_RS10690	COG0183	Belongs to the thiolase family
DKE47_RS10695	COG0583	DNA-binding transcription factor activity
DKE47_RS10750	COG4521	taurine ABC transporter
DKE47_RS10765	COG2188	Transcriptional regulator
DKE47_RS10775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKE47_RS10810	COG3453	Protein conserved in bacteria
DKE47_RS10810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_RS10825	COG1063	alcohol dehydrogenase
DKE47_RS10835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE47_RS10840	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE47_RS10850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE47_RS10855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE47_RS10895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKE47_RS11030	COG0842	Transport permease protein
DKE47_RS11035	COG1131	(ABC) transporter
DKE47_RS11075	COG0730	response to heat
DKE47_RS11080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKE47_RS11110	COG0406	alpha-ribazole phosphatase activity
DKE47_RS11210	COG0822	iron-sulfur transferase activity
DKE47_RS11215	COG0316	Belongs to the HesB IscA family
DKE47_RS11270	COG0702	epimerase
DKE47_RS11305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKE47_RS11415	COG0776	regulation of translation
DKE47_RS11480	COG0084	hydrolase, TatD family'
DKE47_RS11505	COG1132	(ABC) transporter
DKE47_RS11520	COG1192	Involved in chromosome partitioning
DKE47_RS11530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKE47_RS11550	COG0191	fructose-bisphosphate aldolase activity
DKE47_RS11585	COG0640	Transcriptional regulator
DKE47_RS11595	COG3619	membrane
DKE47_RS11600	COG3122	Protein conserved in bacteria
DKE47_RS11605	COG1132	(ABC) transporter
DKE47_RS11625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKE47_RS11630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE47_RS11650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKE47_RS11675	COG2353	YceI-like domain
DKE47_RS11750	COG3539	Fimbrial protein
DKE47_RS11795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DKE47_RS11855	COG1522	sequence-specific DNA binding
DKE47_RS11875	COG0765	amino acid transport
DKE47_RS11915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKE47_RS11925	COG0012	GTP binding
DKE47_RS11950	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DKE47_RS11980	COG1280	lysine exporter protein (LysE YggA)
DKE47_RS11990	COG0386	Belongs to the glutathione peroxidase family
DKE47_RS12070	COG0640	Transcriptional regulator
DKE47_RS12115	COG2175	clavaminate synthase activity
DKE47_RS12175	COG1271	oxidase subunit
DKE47_RS12180	COG1294	oxidase, subunit
DKE47_RS12260	COG1346	cytolysis
DKE47_RS12275	COG0625	glutathione transferase activity
DKE47_RS12280	COG0625	glutathione transferase activity
DKE47_RS12285	COG0583	DNA-binding transcription factor activity
DKE47_RS12310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DKE47_RS12315	COG1280	lysine exporter protein (LysE YggA)
DKE47_RS12335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE47_RS12345	COG0765	amino acid transport
DKE47_RS12350	COG0765	amino acid transport
DKE47_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS12485	COG0318	PFAM AMP-dependent synthetase and ligase
DKE47_RS12495	COG1309	transcriptional regulator
DKE47_RS12500	COG1960	acyl-CoA dehydrogenase activity
DKE47_RS12510	COG1024	Enoyl-CoA hydratase
DKE47_RS12515	COG4770	biotin carboxylase activity
DKE47_RS12560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE47_RS12565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE47_RS12575	COG1960	acyl-CoA dehydrogenase activity
DKE47_RS12580	COG1024	Enoyl-CoA hydratase
DKE47_RS12585	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS12590	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKE47_RS12595	COG0183	Belongs to the thiolase family
DKE47_RS12610	COG1280	lysine exporter protein (LysE YggA)
DKE47_RS12645	COG1960	acyl-CoA dehydrogenase activity
DKE47_RS12660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DKE47_RS12660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKE47_RS12690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE47_RS12735	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_RS12740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE47_RS12750	COG2267	carboxylic ester hydrolase activity
DKE47_RS12770	COG3038	cytochrome b561
DKE47_RS12780	COG1733	regulation of RNA biosynthetic process
DKE47_RS12830	COG2050	protein possibly involved in aromatic compounds catabolism
DKE47_RS12840	COG3327	negative regulation of DNA-templated transcription, initiation
DKE47_RS12875	COG2151	metal-sulfur cluster biosynthetic enzyme
DKE47_RS12885	COG3460	Phenylacetate-CoA oxygenase
DKE47_RS12890	COG3396	Phenylacetate-CoA oxygenase
DKE47_RS12920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DKE47_RS12940	COG0590	tRNA wobble adenosine to inosine editing
DKE47_RS13090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE47_RS13100	COG0864	Transcriptional regulator
DKE47_RS13110	COG1733	regulation of RNA biosynthetic process
DKE47_RS13135	COG1063	alcohol dehydrogenase
DKE47_RS13185	COG0038	chloride channel
DKE47_RS13235	COG3220	belongs to the UPF0276 family
DKE47_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS13280	COG3713	MltA-interacting MipA family protein
DKE47_RS13285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE47_RS13420	COG0789	Transcriptional regulator
DKE47_RS13435	COG0626	cystathionine gamma-synthase activity
DKE47_RS13445	COG1522	sequence-specific DNA binding
DKE47_RS13460	COG4774	siderophore transport
DKE47_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_RS13565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DKE47_RS13605	COG1538	Outer membrane efflux protein
DKE47_RS13610	COG1137	ATPase activity
DKE47_RS13615	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DKE47_RS13625	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DKE47_RS13630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DKE47_RS13630	COG0517	IMP dehydrogenase activity
DKE47_RS13835	COG5377	YqaJ viral recombinase family
DKE47_RS13920	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_RS13955	COG1280	lysine exporter protein (LysE YggA)
DKE47_RS14070	COG2871	sodium ion transport
DKE47_RS14090	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DKE47_RS14095	COG0633	Ferredoxin
DKE47_RS14095	COG0543	2 iron, 2 sulfur cluster binding
DKE47_RS14135	COG0450	alkyl hydroperoxide reductase
DKE47_RS14155	COG3634	alkyl hydroperoxide reductase activity
DKE47_RS14175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKE47_RS14180	COG0625	glutathione transferase activity
DKE47_RS14190	COG2885	chlorophyll binding
DKE47_RS14240	COG1765	OsmC-like protein
DKE47_RS14315	COG2252	PERMEase
DKE47_RS14330	COG0300	oxidoreductase activity
DKE47_RS14340	COG1741	Belongs to the pirin family
DKE47_RS14345	COG1309	transcriptional regulator
DKE47_RS14415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE47_RS14435	COG1024	Enoyl-CoA hydratase
DKE47_RS14480	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_RS14830	COG0582	viral genome integration into host DNA
DKE47_RS14895	COG4239	(ABC) transporter, permease
DKE47_RS14955	COG1279	arginine transmembrane transporter activity
DKE47_RS14985	COG0006	proline dipeptidase activity
DKE47_RS15055	COG3384	dioxygenase
DKE47_RS15075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKE47_RS15095	COG0768	penicillin binding
DKE47_RS15100	COG0742	ribosomal rna small subunit methyltransferase
DKE47_RS15225	COG1773	rubredoxin
DKE47_RS15230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE47_RS15240	COG0583	DNA-binding transcription factor activity
DKE47_RS15320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DKE47_RS15340	COG0306	phosphate transporter
DKE47_RS15375	COG2223	nitrite transmembrane transporter activity
DKE47_RS15380	COG0662	Cupin 2, conserved barrel domain protein
DKE47_RS15380	COG2207	Transcriptional regulator
DKE47_RS15390	COG0242	peptide deformylase activity
DKE47_RS15470	COG1414	Transcriptional regulator
DKE47_RS15500	COG1024	Enoyl-CoA hydratase
DKE47_RS15510	COG1215	transferase activity, transferring glycosyl groups
DKE47_RS15545	COG1607	acyl-coa hydrolase
DKE47_RS15565	COG1309	transcriptional regulator
DKE47_RS15615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE47_RS15720	COG2050	protein possibly involved in aromatic compounds catabolism
DKE47_RS15735	COG1090	epimerase
DKE47_RS15790	COG0735	belongs to the Fur family
DKE47_RS15850	COG2885	chlorophyll binding
DKE47_RS15870	COG2894	cell division
DKE47_RS15895	COG0492	ferredoxin-NADP+ reductase activity
DKE47_RS15910	COG0456	acetyltransferase
DKE47_RS15940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKE47_RS15970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKE47_RS15970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DKE47_RS16000	COG0657	acetylesterase activity
DKE47_RS16010	COG0473	3-isopropylmalate dehydrogenase activity
DKE47_RS16035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE47_RS16090	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DKE47_RS16120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE47_RS16165	COG0351	phosphomethylpyrimidine kinase
DKE47_RS16165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE47_RS16165	COG0352	thiamine-phosphate diphosphorylase activity
DKE47_RS16170	COG1652	LysM domain
DKE47_RS16195	COG1399	metal-binding, possibly nucleic acid-binding protein
DKE47_RS16200	COG3101	peptidyl-lysine hydroxylation
DKE47_RS16205	COG0009	L-threonylcarbamoyladenylate synthase
DKE47_RS16210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKE47_RS16215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKE47_RS16230	COG4106	trans-aconitate 2-methyltransferase activity
DKE47_RS16250	COG1877	trehalose-phosphatase activity
DKE47_RS16255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DKE47_RS16370	COG0489	protein tyrosine kinase activity
DKE47_RS16425	COG2081	HI0933 family
DKE47_RS16485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DKE47_RS16540	COG3706	GGDEF domain
DKE47_RS16555	COG0745	RESPONSE REGULATOR receiver
DKE47_RS16575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKE47_RS16630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE47_RS16645	COG0583	DNA-binding transcription factor activity
DKE47_RS16655	COG0583	DNA-binding transcription factor activity
DKE47_RS16720	COG1063	alcohol dehydrogenase
DKE47_RS16755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DKE47_RS16790	COG0561	phosphatase activity
DKE47_RS16795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKE47_RS16815	COG1214	PFAM Peptidase M22, glycoprotease
DKE47_RS16955	COG1846	Transcriptional regulator
DKE47_RS16960	COG1764	response to oxidative stress
DKE47_RS17010	COG0248	Ppx GppA phosphatase
DKE47_RS17065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKE47_RS17095	COG0318	PFAM AMP-dependent synthetase and ligase
DKE47_RS17100	COG3028	Belongs to the UPF0307 family
DKE47_RS17105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE47_RS17135	COG1555	photosystem II stabilization
DKE47_RS17185	COG3622	Belongs to the hyi family
DKE47_RS17225	COG2814	Major facilitator Superfamily
DKE47_RS17255	COG0492	ferredoxin-NADP+ reductase activity
DKE47_RS17275	COG0640	Transcriptional regulator
DKE47_RS17450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKE47_RS17480	COG0084	hydrolase, TatD family'
DKE47_RS17495	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DKE47_RS17540	COG1309	transcriptional regulator
DKE47_RS17570	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DKE47_RS17585	COG3321	synthase
DKE47_RS17585	COG0604	alcohol dehydrogenase
DKE47_RS17590	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DKE47_RS17605	COG4221	oxidoreductase activity
DKE47_RS17775	COG0440	acetolactate synthase activity
DKE47_RS17835	COG1162	GTPase activity
DKE47_RS17845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DKE47_RS17865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DKE47_RS17950	COG3265	gluconokinase activity
DKE47_RS17980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DKE47_RS17980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DKE47_RS18000	COG0740	serine-type endopeptidase activity
DKE47_RS18020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKE47_RS18030	COG2813	Specifically methylates the guanine in position
DKE47_RS18030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKE47_RS18180	COG0724	RNA recognition motif
DKE47_RS18185	COG0210	DNA helicase
DKE47_RS18215	COG1733	regulation of RNA biosynthetic process
DKE47_RS18225	COG2900	Belongs to the SlyX family
DKE47_RS18245	COG1560	Kdo2-lipid A biosynthetic process
DKE47_RS18310	COG0473	3-isopropylmalate dehydrogenase activity
DKE47_RS18380	COG0583	DNA-binding transcription factor activity
DKE47_RS18390	COG0625	glutathione transferase activity
DKE47_RS18395	COG2378	regulation of single-species biofilm formation
DKE47_RS18445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKE47_RS18470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DKE47_RS18495	COG0493	'glutamate synthase
DKE47_RS18495	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE47_RS18505	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DKE47_RS18510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_RS18550	COG4535	Mg2 and Co2 transporter CorC
DKE47_RS18560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE47_RS18580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKE47_RS18590	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKE47_RS18605	COG0789	Transcriptional regulator
DKE47_RS18625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DKE47_RS18630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKE47_RS18665	COG2226	methyltransferase
DKE47_RS18680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE47_RS18710	COG1006	Multisubunit Na H antiporter MnhC subunit
DKE47_RS18725	COG2212	antiporter activity
DKE47_RS18735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKE47_RS18795	COG0237	dephospho-CoA kinase activity
DKE47_RS18830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKE47_RS18845	COG1289	transmembrane transporter activity
DKE47_RS18860	COG2169	Transcriptional regulator
DKE47_RS18860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKE47_RS18865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKE47_RS18960	COG2056	Na+-H+ antiporter family
DKE47_RS19065	COG0546	phosphoglycolate phosphatase activity
DKE47_RS19070	COG1716	ATPase activity
DKE47_RS19125	COG3275	phosphorelay sensor kinase activity
DKE47_RS19170	COG0494	nUDIX hydrolase
DKE47_RS19180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE47_RS19185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKE47_RS19215	COG4974	Belongs to the 'phage' integrase family
DKE47_RS19230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DKE47_RS19255	COG0793	Belongs to the peptidase S41A family
DKE47_RS19265	COG0795	lipopolysaccharide-transporting ATPase activity
DKE47_RS19315	COG0004	ammonium transporteR
DKE47_RS19320	COG0347	Belongs to the P(II) protein family
DKE47_RS19395	COG0640	Transcriptional regulator
DKE47_RS19405	COG0789	Transcriptional regulator
DKE47_RS19460	COG0606	chelatase, subunit chli
DKE47_RS19495	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DKE47_RS19520	COG0477	Major facilitator Superfamily
DKE47_RS19525	COG2860	membrane
DKE47_RS19590	COG0655	NAD(P)H dehydrogenase (quinone) activity
DKE47_RS19605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE47_RS19640	COG1309	transcriptional regulator
DKE47_RS19675	COG0758	DNA mediated transformation
DKE47_RS19705	COG0386	Belongs to the glutathione peroxidase family
DKE47_RS19715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DKE47_RS19775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKE47_RS19780	COG1280	lysine exporter protein (LysE YggA)
DKE47_RS19785	COG2837	iron assimilation
DKE47_RS19825	COG0735	belongs to the Fur family
DKE47_RS19835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE47_RS19840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE47_RS19840	COG0519	Catalyzes the synthesis of GMP from XMP
DKE47_RS19845	COG4399	Belongs to the UPF0754 family
DKE47_RS19850	COG2259	Doxx family
DKE47_RS19880	COG0271	Belongs to the BolA IbaG family
DKE47_RS19935	COG0318	PFAM AMP-dependent synthetase and ligase
DKE47_RS19960	COG1024	Enoyl-CoA hydratase
DKE47_RS19975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKE47_RS20010	COG0251	oxidation-reduction process
DKE47_RS20100	COG1403	HNH endonuclease
DKE47_RS20130	COG1802	Transcriptional regulator
DKE47_RS20135	COG1448	Aminotransferase
DKE47_RS20150	COG2186	Transcriptional regulator
DKE47_RS20175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKE47_RS20190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKE47_RS20205	COG0438	transferase activity, transferring glycosyl groups
DKE47_RS20240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DKE47_RS20250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DKE47_RS20255	COG1596	polysaccharide export
DKE47_RS20280	COG0728	peptidoglycan biosynthetic process
DKE47_RS20340	COG0546	phosphoglycolate phosphatase activity
DKE47_RS20370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKE47_RS20375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE47_RS20385	COG1116	anion transmembrane transporter activity
DKE47_RS20395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DKE47_RS20405	COG0196	riboflavin kinase activity
DKE47_RS20420	COG1047	Peptidyl-prolyl cis-trans
DKE47_RS20460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DKE47_RS20545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKE47_RS20560	COG0861	Integral membrane protein TerC family
DKE47_RS20570	COG0754	glutathionylspermidine amidase activity
DKE47_RS20600	COG1230	cation diffusion facilitator family transporter
DKE47_RS21510	COG1373	ATPase (AAA superfamily
DKE47_RS21635	COG2369	cell adhesion
DKE47_RS21665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE47_RS21710	COG0582	viral genome integration into host DNA
DKE47_RS21735	COG1475	DNA binding
DKE47_RS21740	COG1785	Belongs to the alkaline phosphatase family