locus-tag	class	description
AL533_RS00015	COG1289	transmembrane transporter activity
AL533_RS00025	COG0628	permease
AL533_RS00030	COG1192	Involved in chromosome partitioning
AL533_RS00060	COG0833	amino acid
AL533_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL533_RS00070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL533_RS00080	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS00120	COG0583	DNA-binding transcription factor activity
AL533_RS00165	COG0517	IMP dehydrogenase activity
AL533_RS00170	COG1983	PspC domain protein
AL533_RS00180	COG1960	acyl-CoA dehydrogenase activity
AL533_RS00195	COG0408	coproporphyrinogen oxidase activity
AL533_RS00220	COG1127	ABC transporter
AL533_RS00225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL533_RS00235	COG2854	intermembrane phospholipid transfer
AL533_RS00245	COG0598	Magnesium transport protein CorA
AL533_RS00255	COG0494	nUDIX hydrolase
AL533_RS00260	COG1040	competence protein
AL533_RS00265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL533_RS00285	COG1946	Acyl-CoA thioesterase
AL533_RS00290	COG1301	dicarboxylic acid transport
AL533_RS00305	COG1959	2 iron, 2 sulfur cluster binding
AL533_RS00310	COG1017	nitric oxide dioxygenase activity
AL533_RS00310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL533_RS00315	COG0433	COG0433 Predicted ATPase
AL533_RS00320	COG0626	cystathionine gamma-synthase activity
AL533_RS00335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL533_RS00340	COG0088	Forms part of the polypeptide exit tunnel
AL533_RS00475	COG1960	acyl-CoA dehydrogenase activity
AL533_RS00480	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL533_RS00510	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL533_RS00515	COG0339	signal peptide processing
AL533_RS00520	COG0557	exoribonuclease II activity
AL533_RS00565	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL533_RS00570	COG2207	Transcriptional regulator
AL533_RS00580	COG1295	ribonuclease BN
AL533_RS00615	COG1702	phosphate starvation-inducible protein PhoH
AL533_RS00625	COG0739	heme binding
AL533_RS00625	COG1196	nuclear chromosome segregation
AL533_RS00625	COG0741	lytic transglycosylase activity
AL533_RS00655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL533_RS00660	COG1183	phosphatidylcholine synthase activity
AL533_RS00710	COG1960	acyl-CoA dehydrogenase activity
AL533_RS00715	COG1309	transcriptional regulator
AL533_RS00730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL533_RS00785	COG2969	positive regulation of protein catabolic process
AL533_RS00795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL533_RS00800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL533_RS00805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL533_RS00810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL533_RS00815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL533_RS00835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL533_RS00845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL533_RS00850	COG1408	metallophosphoesterase
AL533_RS00860	COG2199	diguanylate cyclase activity
AL533_RS00920	COG1607	acyl-coa hydrolase
AL533_RS00955	COG2350	Protein conserved in bacteria
AL533_RS00965	COG0613	PHP domain protein
AL533_RS00970	COG3781	membrane
AL533_RS00980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL533_RS00985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL533_RS00995	COG1862	Preprotein translocase
AL533_RS01025	COG0784	Response regulator, receiver
AL533_RS01025	COG2198	Histidine kinase
AL533_RS01025	COG2205	protein histidine kinase activity
AL533_RS01025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL533_RS01030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL533_RS01045	COG2194	sulfuric ester hydrolase activity
AL533_RS01055	COG0726	polysaccharide deacetylase
AL533_RS01060	COG0463	Glycosyl transferase, family 2
AL533_RS01065	COG0438	transferase activity, transferring glycosyl groups
AL533_RS01130	COG1960	acyl-CoA dehydrogenase activity
AL533_RS01135	COG1960	acyl-CoA dehydrogenase activity
AL533_RS01145	COG2205	protein histidine kinase activity
AL533_RS01150	COG0745	RESPONSE REGULATOR receiver
AL533_RS01155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL533_RS01175	COG2096	Adenosyltransferase
AL533_RS01230	COG0285	dihydrofolate synthase activity
AL533_RS01250	COG0450	alkyl hydroperoxide reductase
AL533_RS01265	COG0477	Major facilitator Superfamily
AL533_RS01270	COG1272	protein, Hemolysin III
AL533_RS01280	COG2153	protein acetylation
AL533_RS01300	COG0183	Belongs to the thiolase family
AL533_RS01305	COG2207	Transcriptional regulator
AL533_RS01325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL533_RS01345	COG0183	Belongs to the thiolase family
AL533_RS01355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL533_RS01355	COG2885	chlorophyll binding
AL533_RS01360	COG1690	Belongs to the RtcB family
AL533_RS01365	COG0833	amino acid
AL533_RS01375	COG2233	PERMEase
AL533_RS01380	COG1217	gtp-binding protein TYPA
AL533_RS01405	COG2094	Belongs to the DNA glycosylase MPG family
AL533_RS01410	COG4772	TonB-dependent receptor
AL533_RS01415	COG1902	pentaerythritol trinitrate reductase activity
AL533_RS01430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL533_RS01435	COG0354	folic acid binding
AL533_RS01445	COG3189	MarR family transcriptional regulator
AL533_RS01450	COG2824	Alkylphosphonate utilization operon protein PhnA
AL533_RS01455	COG3422	double-strand break repair
AL533_RS01495	COG0840	transmembrane signaling receptor activity
AL533_RS01525	COG2832	Protein of unknown function (DUF454)
AL533_RS01530	COG1376	ErfK ybiS ycfS ynhG family protein
AL533_RS01570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL533_RS01580	COG1289	transmembrane transporter activity
AL533_RS01585	COG2814	Major facilitator Superfamily
AL533_RS01610	COG1115	amino acid carrier protein
AL533_RS01615	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL533_RS01620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL533_RS01625	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AL533_RS01655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL533_RS01665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL533_RS01670	COG1077	Cell shape determining protein MreB Mrl
AL533_RS01675	COG1792	Involved in formation and maintenance of cell shape
AL533_RS01680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL533_RS01685	COG0424	maF-like protein
AL533_RS01690	COG1530	ribonuclease E activity
AL533_RS01700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL533_RS01720	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL533_RS01745	COG2207	Transcriptional regulator
AL533_RS01775	COG3046	protein related to deoxyribodipyrimidine photolyase
AL533_RS01780	COG2816	NAD+ diphosphatase activity
AL533_RS01785	COG1113	amino acid transport
AL533_RS01790	COG2828	Protein conserved in bacteria
AL533_RS01795	COG0142	geranyltranstransferase activity
AL533_RS01800	COG2315	Protein conserved in bacteria
AL533_RS01815	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL533_RS01835	COG2194	sulfuric ester hydrolase activity
AL533_RS01840	COG0745	RESPONSE REGULATOR receiver
AL533_RS01845	COG0642	Histidine kinase
AL533_RS01855	COG0004	ammonium transporteR
AL533_RS01865	COG0583	DNA-binding transcription factor activity
AL533_RS01885	COG0525	valine-tRNA ligase activity
AL533_RS01895	COG0525	valine-tRNA ligase activity
AL533_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS01915	COG0393	Putative heavy-metal-binding
AL533_RS01920	COG0393	Putative heavy-metal-binding
AL533_RS01925	COG1538	Outer membrane efflux protein
AL533_RS01935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS01940	COG0671	phosphoesterase, PA-phosphatase related
AL533_RS01970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL533_RS01985	COG1648	precorrin-2 dehydrogenase activity
AL533_RS01985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL533_RS01990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL533_RS01995	COG1733	regulation of RNA biosynthetic process
AL533_RS02005	COG0531	amino acid
AL533_RS02020	COG0321	lipoyl(octanoyl) transferase activity
AL533_RS02025	COG2921	Belongs to the UPF0250 family
AL533_RS02060	COG2009	succinate dehydrogenase
AL533_RS02065	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL533_RS02070	COG1053	succinate dehydrogenase
AL533_RS02075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL533_RS02100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL533_RS02120	COG2354	Protein conserved in bacteria
AL533_RS02125	COG2321	neutral zinc metallopeptidase
AL533_RS02145	COG2843	Capsule synthesis protein
AL533_RS02175	COG0589	response to stress
AL533_RS02185	COG0251	oxidation-reduction process
AL533_RS02190	COG1309	transcriptional regulator
AL533_RS02205	COG0505	Belongs to the CarA family
AL533_RS02235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL533_RS02240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL533_RS02290	COG0477	Major facilitator Superfamily
AL533_RS02295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL533_RS02310	COG1597	lipid kinase activity
AL533_RS02315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL533_RS02335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL533_RS02340	COG0584	glycerophosphoryl diester phosphodiesterase
AL533_RS02360	COG0741	lytic transglycosylase activity
AL533_RS02385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL533_RS02400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL533_RS02410	COG3811	Belongs to the UPF0386 family
AL533_RS02460	COG1309	transcriptional regulator
AL533_RS02465	COG1902	pentaerythritol trinitrate reductase activity
AL533_RS02470	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL533_RS02470	COG0596	Alpha beta hydrolase
AL533_RS02480	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS02490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS02495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL533_RS02500	COG0778	Nitroreductase
AL533_RS02505	COG0300	oxidoreductase activity
AL533_RS02515	COG1929	Belongs to the glycerate kinase type-1 family
AL533_RS02520	COG0243	molybdopterin cofactor binding
AL533_RS02530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL533_RS02545	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL533_RS02560	COG1113	amino acid transport
AL533_RS02565	COG1113	amino acid transport
AL533_RS02575	COG0019	diaminopimelate decarboxylase activity
AL533_RS02585	COG1280	lysine exporter protein (LysE YggA)
AL533_RS02590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL533_RS02610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL533_RS02620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL533_RS02630	COG0463	Glycosyl transferase, family 2
AL533_RS02650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS02680	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL533_RS02685	COG1136	(ABC) transporter
AL533_RS02700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL533_RS02700	COG0616	signal peptide processing
AL533_RS02705	COG0596	Alpha beta hydrolase
AL533_RS02710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL533_RS02720	COG0628	permease
AL533_RS02755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL533_RS02775	COG0823	Involved in the tonB-independent uptake of proteins
AL533_RS02795	COG0824	Thioesterase
AL533_RS02800	COG1473	amidohydrolase
AL533_RS02820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL533_RS02820	COG0047	phosphoribosylformylglycinamidine synthase activity
AL533_RS02825	COG2814	Major facilitator Superfamily
AL533_RS02840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL533_RS02845	COG1024	Enoyl-CoA hydratase
AL533_RS02850	COG1051	belongs to the nudix hydrolase family
AL533_RS02850	COG1056	cytidyltransferase-related domain
AL533_RS02865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL533_RS02880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL533_RS02885	COG0602	queuosine metabolic process
AL533_RS02895	COG4625	pathogenesis
AL533_RS02900	COG0583	DNA-binding transcription factor activity
AL533_RS02905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL533_RS02910	COG4208	sulfate ABC transporter
AL533_RS02915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL533_RS02925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL533_RS02930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL533_RS02935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL533_RS02955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL533_RS02965	COG0481	GTPase activity
AL533_RS02970	COG0681	Belongs to the peptidase S26 family
AL533_RS02985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL533_RS02995	COG1381	Involved in DNA repair and RecF pathway recombination
AL533_RS03000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL533_RS03010	COG4221	oxidoreductase activity
AL533_RS03040	COG0436	Aminotransferase
AL533_RS03060	COG0556	nucleotide-excision repair
AL533_RS03115	COG2070	2-Nitropropane dioxygenase
AL533_RS03145	COG1215	transferase activity, transferring glycosyl groups
AL533_RS03160	COG0415	Belongs to the DNA photolyase family
AL533_RS03170	COG1252	NADH dehydrogenase
AL533_RS03175	COG1686	Belongs to the peptidase S11 family
AL533_RS03190	COG1187	pseudouridine synthase activity
AL533_RS03215	COG0477	Major facilitator Superfamily
AL533_RS03220	COG0583	DNA-binding transcription factor activity
AL533_RS03225	COG1823	symporter activity
AL533_RS03235	COG0612	Peptidase, M16
AL533_RS03260	COG0352	thiamine-phosphate diphosphorylase activity
AL533_RS03295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL533_RS03320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL533_RS03325	COG0076	glutamate decarboxylase activity
AL533_RS03335	COG1522	sequence-specific DNA binding
AL533_RS03340	COG3961	Belongs to the TPP enzyme family
AL533_RS03345	COG1113	amino acid transport
AL533_RS03350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL533_RS03355	COG0573	inorganic phosphate transmembrane transporter activity
AL533_RS03365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL533_RS03370	COG0616	signal peptide processing
AL533_RS03385	COG3647	Membrane
AL533_RS03410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL533_RS03415	COG1686	Belongs to the peptidase S11 family
AL533_RS03440	COG0583	DNA-binding transcription factor activity
AL533_RS03445	COG1067	ATP-dependent peptidase activity
AL533_RS03470	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL533_RS03485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL533_RS03490	COG1966	Carbon starvation protein
AL533_RS03495	COG2879	small protein
AL533_RS03540	COG2964	Protein conserved in bacteria
AL533_RS03545	COG1741	Belongs to the pirin family
AL533_RS03565	COG3739	integral membrane protein
AL533_RS03585	COG0302	gtp cyclohydrolase
AL533_RS03595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL533_RS03605	COG2840	Smr protein MutS2
AL533_RS03625	COG0308	aminopeptidase N
AL533_RS03630	COG0512	Glutamine amidotransferase of anthranilate synthase
AL533_RS03675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL533_RS03905	COG0582	viral genome integration into host DNA
AL533_RS03920	COG0174	glutamine synthetase
AL533_RS03930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL533_RS03965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL533_RS03970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL533_RS03975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL533_RS03995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL533_RS04000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL533_RS04005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL533_RS04020	COG1960	acyl-CoA dehydrogenase activity
AL533_RS04025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL533_RS04030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL533_RS04040	COG2223	nitrite transmembrane transporter activity
AL533_RS04050	COG0024	Methionine aminopeptidase
AL533_RS04055	COG0052	Belongs to the universal ribosomal protein uS2 family
AL533_RS04070	COG2207	Transcriptional regulator
AL533_RS04095	COG2951	lytic endotransglycosylase activity
AL533_RS04100	COG0772	Belongs to the SEDS family
AL533_RS04115	COG0842	Transport permease protein
AL533_RS04120	COG1131	(ABC) transporter
AL533_RS04145	COG3328	transposase activity
AL533_RS04210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS04225	COG4215	(ABC) transporter
AL533_RS04230	COG4160	amino acid transport
AL533_RS04235	COG4598	ABC transporter
AL533_RS04245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL533_RS04250	COG0826	peptidase U32
AL533_RS04255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL533_RS04260	COG0384	phenazine biosynthesis protein PhzF
AL533_RS04270	COG1720	tRNA m6t6A37 methyltransferase activity
AL533_RS04280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL533_RS04285	COG3111	PFAM Bacterial OB fold (BOF) protein
AL533_RS04295	COG0642	Histidine kinase
AL533_RS04305	COG0494	nUDIX hydrolase
AL533_RS04315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL533_RS04320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL533_RS04325	COG3139	Protein of unknown function (DUF1315)
AL533_RS04330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL533_RS04340	COG1301	dicarboxylic acid transport
AL533_RS04345	COG1960	acyl-CoA dehydrogenase activity
AL533_RS04355	COG2819	hydrolase of the alpha beta superfamily
AL533_RS04365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL533_RS04375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL533_RS04380	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL533_RS04385	COG1234	tRNA 3'-trailer cleavage
AL533_RS04410	COG2363	Small membrane protein
AL533_RS04430	COG0513	Belongs to the DEAD box helicase family
AL533_RS04440	COG0778	Nitroreductase
AL533_RS04470	COG1286	toxin biosynthetic process
AL533_RS04500	COG1610	YqeY-like protein
AL533_RS04530	COG2815	serine threonine protein kinase
AL533_RS04530	COG0515	serine threonine protein kinase
AL533_RS04555	COG2831	hemolysin activation secretion protein
AL533_RS04565	COG3328	transposase activity
AL533_RS04580	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AL533_RS04670	COG2226	methyltransferase
AL533_RS04680	COG3111	PFAM Bacterial OB fold (BOF) protein
AL533_RS04695	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL533_RS04700	COG0786	glutamate:sodium symporter activity
AL533_RS04705	COG0475	glutathione-regulated potassium exporter activity
AL533_RS04705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL533_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS04775	COG1073	alpha beta
AL533_RS04785	COG0583	DNA-binding transcription factor activity
AL533_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS04795	COG2207	Transcriptional regulator
AL533_RS04830	COG2995	paraquat-inducible protein a
AL533_RS04835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL533_RS04835	COG3008	intermembrane lipid transfer
AL533_RS04845	COG2351	hydroxyisourate hydrolase activity
AL533_RS04860	COG5002	protein histidine kinase activity
AL533_RS04885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL533_RS04895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL533_RS04900	COG0642	Histidine kinase
AL533_RS04905	COG0745	RESPONSE REGULATOR receiver
AL533_RS04940	COG0625	glutathione transferase activity
AL533_RS04955	COG1301	dicarboxylic acid transport
AL533_RS04970	COG2011	ABC-type metal ion transport system permease component
AL533_RS04975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL533_RS04990	COG0151	Belongs to the GarS family
AL533_RS04995	COG0138	bifunctional purine biosynthesis protein purh
AL533_RS05000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL533_RS05030	COG2308	Evidence 4 Homologs of previously reported genes of
AL533_RS05040	COG1305	Transglutaminase-like
AL533_RS05050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL533_RS05055	COG0305	Participates in initiation and elongation during chromosome replication
AL533_RS05080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL533_RS05090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL533_RS05120	COG0726	polysaccharide deacetylase
AL533_RS05120	COG1649	PFAM Uncharacterised BCR, COG1649
AL533_RS05125	COG1215	transferase activity, transferring glycosyl groups
AL533_RS05130	COG3658	cytochrome
AL533_RS05140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL533_RS05160	COG0583	DNA-binding transcription factor activity
AL533_RS05170	COG3328	transposase activity
AL533_RS05185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL533_RS05190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL533_RS05205	COG1960	acyl-CoA dehydrogenase activity
AL533_RS05210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL533_RS05215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL533_RS05240	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AL533_RS05245	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL533_RS05250	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL533_RS05255	COG2205	protein histidine kinase activity
AL533_RS05260	COG0745	RESPONSE REGULATOR receiver
AL533_RS05265	COG0174	glutamine synthetase
AL533_RS05285	COG0729	surface antigen
AL533_RS05315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL533_RS05325	COG0583	DNA-binding transcription factor activity
AL533_RS05340	COG1187	pseudouridine synthase activity
AL533_RS05360	COG0802	atpase or kinase
AL533_RS05365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL533_RS05375	COG1923	regulation of RNA biosynthetic process
AL533_RS05380	COG0697	spore germination
AL533_RS05410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL533_RS05410	COG0519	Catalyzes the synthesis of GMP from XMP
AL533_RS05415	COG4302	ethanolamine ammonia-lyase activity
AL533_RS05420	COG4303	Ethanolamine ammonia lyase large subunit
AL533_RS05425	COG0531	amino acid
AL533_RS05445	COG1454	alcohol dehydrogenase
AL533_RS05450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL533_RS05475	COG0308	aminopeptidase N
AL533_RS05515	COG1605	Chorismate mutase
AL533_RS05550	COG4264	IucA IucC family
AL533_RS05560	COG4264	IucA IucC family
AL533_RS05565	COG2423	ornithine cyclodeaminase activity
AL533_RS05570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL533_RS05575	COG0668	transmembrane transport
AL533_RS05620	COG0488	(ABC) transporter
AL533_RS05625	COG0589	response to stress
AL533_RS05650	COG3135	benzoate transporter
AL533_RS05655	COG1522	sequence-specific DNA binding
AL533_RS05665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL533_RS05670	COG0583	DNA-binding transcription factor activity
AL533_RS05680	COG0183	Belongs to the thiolase family
AL533_RS05690	COG2030	dehydratase
AL533_RS05695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL533_RS05720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL533_RS05730	COG0824	Thioesterase
AL533_RS05735	COG1454	alcohol dehydrogenase
AL533_RS05745	COG1335	isochorismatase
AL533_RS05760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL533_RS05790	COG0069	glutamate synthase activity
AL533_RS05840	COG3328	transposase activity
AL533_RS05995	COG5410	chromosome segregation
AL533_RS06000	COG3567	Phage-associated protein, HI1409 family
AL533_RS06015	COG3566	protein conserved in bacteria
AL533_RS06095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL533_RS06145	COG2814	Major facilitator Superfamily
AL533_RS06155	COG0439	Biotin carboxylase
AL533_RS06160	COG0511	ligase activity, forming carbon-carbon bonds
AL533_RS06180	COG1116	anion transmembrane transporter activity
AL533_RS06180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL533_RS06185	COG0745	RESPONSE REGULATOR receiver
AL533_RS06195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL533_RS06195	COG2146	nitrite reductase [NAD(P)H] activity
AL533_RS06200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL533_RS06205	COG0243	molybdopterin cofactor binding
AL533_RS06215	COG0243	molybdopterin cofactor binding
AL533_RS06220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL533_RS06235	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL533_RS06235	COG0315	cyclic pyranopterin monophosphate synthase activity
AL533_RS06240	COG0303	'Molybdopterin
AL533_RS06250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL533_RS06255	COG0697	spore germination
AL533_RS06275	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL533_RS06280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL533_RS06340	COG2204	response regulator
AL533_RS06345	COG3852	Histidine kinase
AL533_RS06370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL533_RS06375	COG0575	Belongs to the CDS family
AL533_RS06410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL533_RS06425	COG2137	regulation of response to DNA damage stimulus
AL533_RS06435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL533_RS06440	COG1011	Hydrolase
AL533_RS06460	COG1522	sequence-specific DNA binding
AL533_RS06470	COG1113	amino acid transport
AL533_RS06485	COG0659	secondary active sulfate transmembrane transporter activity
AL533_RS06490	COG2135	peptidase activity
AL533_RS06505	COG3300	MHYT domain
AL533_RS06505	COG5001	Diguanylate cyclase
AL533_RS06520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL533_RS06520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL533_RS06520	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL533_RS06525	COG1105	Belongs to the carbohydrate kinase PfkB family
AL533_RS06530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL533_RS06530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL533_RS06560	COG0024	Methionine aminopeptidase
AL533_RS06565	COG0583	DNA-binding transcription factor activity
AL533_RS06575	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL533_RS06580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL533_RS06585	COG0516	GMP reductase activity
AL533_RS06585	COG0517	IMP dehydrogenase activity
AL533_RS06610	COG0552	protein localization to endoplasmic reticulum
AL533_RS06620	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL533_RS06635	COG4890	Cyd operon protein YbgT
AL533_RS06640	COG1294	oxidase, subunit
AL533_RS06655	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL533_RS06665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL533_RS06670	COG4774	siderophore transport
AL533_RS06685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL533_RS06690	COG0569	domain protein
AL533_RS06695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL533_RS06725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL533_RS06730	COG0542	response to heat
AL533_RS06755	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL533_RS06755	COG1902	pentaerythritol trinitrate reductase activity
AL533_RS06795	COG2323	membrane
AL533_RS06805	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL533_RS06815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL533_RS06820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL533_RS06825	COG0183	Belongs to the thiolase family
AL533_RS06830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL533_RS06835	COG0596	Alpha beta hydrolase
AL533_RS06840	COG2271	Major facilitator Superfamily
AL533_RS06845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL533_RS06850	COG3485	protocatechuate 3,4-dioxygenase
AL533_RS06855	COG3485	protocatechuate 3,4-dioxygenase
AL533_RS06860	COG0710	3-dehydroquinate dehydratase activity
AL533_RS06865	COG3420	alginic acid biosynthetic process
AL533_RS06870	COG3659	wide pore channel activity
AL533_RS06875	COG4993	Dehydrogenase
AL533_RS06885	COG2391	methyltransferase activity
AL533_RS06900	COG1414	Transcriptional regulator
AL533_RS06905	COG0583	DNA-binding transcription factor activity
AL533_RS06910	COG1960	acyl-CoA dehydrogenase activity
AL533_RS06935	COG2814	Major facilitator Superfamily
AL533_RS06945	COG0154	amidase activity
AL533_RS06965	COG4638	Rieske (2fe-2S)
AL533_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS06985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL533_RS06995	COG3733	amine oxidase
AL533_RS07005	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS07010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL533_RS07015	COG0183	Belongs to the thiolase family
AL533_RS07025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL533_RS07030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL533_RS07040	COG4829	muconolactone delta-isomerase
AL533_RS07045	COG4948	Mandelate Racemase Muconate Lactonizing
AL533_RS07050	COG0583	DNA-binding transcription factor activity
AL533_RS07060	COG2186	Transcriptional regulator
AL533_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS07105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL533_RS07115	COG0789	Transcriptional regulator
AL533_RS07130	COG1309	transcriptional regulator
AL533_RS07145	COG1309	transcriptional regulator
AL533_RS07150	COG2831	hemolysin activation secretion protein
AL533_RS07155	COG3210	domain, Protein
AL533_RS07195	COG2188	Transcriptional regulator
AL533_RS07200	COG0583	DNA-binding transcription factor activity
AL533_RS07220	COG1566	PFAM secretion protein HlyD family protein
AL533_RS07235	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS07240	COG0129	dihydroxy-acid dehydratase activity
AL533_RS07250	COG0583	DNA-binding transcription factor activity
AL533_RS07255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL533_RS07265	COG2084	Dehydrogenase
AL533_RS07270	COG2207	Transcriptional regulator
AL533_RS07285	COG1064	alcohol dehydrogenase
AL533_RS07305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL533_RS07310	COG1120	ATPase activity
AL533_RS07330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL533_RS07380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL533_RS07460	COG2259	Doxx family
AL533_RS07465	COG0583	DNA-binding transcription factor activity
AL533_RS07470	COG2205	protein histidine kinase activity
AL533_RS07475	COG0745	RESPONSE REGULATOR receiver
AL533_RS07480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS07485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL533_RS07490	COG1538	Outer membrane efflux protein
AL533_RS07500	COG2072	flavoprotein involved in K transport
AL533_RS07510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL533_RS07640	COG3539	Fimbrial protein
AL533_RS07665	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL533_RS07675	COG0753	catalase activity
AL533_RS07690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL533_RS07755	COG4771	TonB-dependent receptor
AL533_RS07760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL533_RS07765	COG1535	isochorismatase
AL533_RS07765	COG3433	isochorismatase activity
AL533_RS07770	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL533_RS07775	COG1169	isochorismate synthase
AL533_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS07790	COG3251	PFAM MbtH domain protein
AL533_RS07795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL533_RS07825	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL533_RS07830	COG4149	molybdate abc transporter
AL533_RS07835	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL533_RS07845	COG4638	Rieske (2fe-2S)
AL533_RS07850	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL533_RS07855	COG0543	2 iron, 2 sulfur cluster binding
AL533_RS07855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL533_RS07870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL533_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS07895	COG2207	Transcriptional regulator
AL533_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS07905	COG2610	gluconate transmembrane transporter activity
AL533_RS07910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL533_RS07940	COG0583	DNA-binding transcription factor activity
AL533_RS07955	COG2031	fatty acid transporter
AL533_RS07960	COG0183	Belongs to the thiolase family
AL533_RS07965	COG0583	DNA-binding transcription factor activity
AL533_RS07970	COG0583	DNA-binding transcription factor activity
AL533_RS07985	COG1027	Aspartate ammonia-lyase
AL533_RS07995	COG0477	Major facilitator Superfamily
AL533_RS08015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL533_RS08020	COG4521	taurine ABC transporter
AL533_RS08035	COG2188	Transcriptional regulator
AL533_RS08045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL533_RS08050	COG1733	regulation of RNA biosynthetic process
AL533_RS08055	COG2207	Transcriptional regulator
AL533_RS08055	COG3708	Transcriptional regulator
AL533_RS08070	COG0730	response to heat
AL533_RS08080	COG3453	Protein conserved in bacteria
AL533_RS08080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL533_RS08090	COG3781	membrane
AL533_RS08095	COG1063	alcohol dehydrogenase
AL533_RS08105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL533_RS08110	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL533_RS08115	COG0022	dehydrogenase e1 component
AL533_RS08120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL533_RS08125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL533_RS08165	COG0133	tryptophan synthase activity
AL533_RS08175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL533_RS08210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL533_RS08235	COG2226	methyltransferase
AL533_RS08290	COG0842	Transport permease protein
AL533_RS08295	COG0842	Transport permease protein
AL533_RS08300	COG1131	(ABC) transporter
AL533_RS08315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL533_RS08320	COG4773	Receptor
AL533_RS08340	COG0730	response to heat
AL533_RS08345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL533_RS08355	COG4772	TonB-dependent receptor
AL533_RS08370	COG0406	alpha-ribazole phosphatase activity
AL533_RS08375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL533_RS08400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL533_RS08415	COG1960	acyl-CoA dehydrogenase activity
AL533_RS08420	COG1960	acyl-CoA dehydrogenase activity
AL533_RS08425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL533_RS08430	COG2207	Transcriptional regulator
AL533_RS08435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL533_RS08440	COG0776	regulation of translation
AL533_RS08465	COG0822	iron-sulfur transferase activity
AL533_RS08470	COG0316	Belongs to the HesB IscA family
AL533_RS08500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL533_RS08520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL533_RS08525	COG0702	epimerase
AL533_RS08555	COG4172	Belongs to the ABC transporter superfamily
AL533_RS08560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL533_RS08565	COG0601	transmembrane transport
AL533_RS08570	COG0339	signal peptide processing
AL533_RS08595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL533_RS08625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL533_RS08630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL533_RS08645	COG2431	L-lysine efflux transmembrane transporter activity
AL533_RS08660	COG0776	regulation of translation
AL533_RS08725	COG0084	hydrolase, TatD family'
AL533_RS08745	COG1663	tetraacyldisaccharide 4'-kinase activity
AL533_RS08750	COG1132	(ABC) transporter
AL533_RS08760	COG0811	peptide transport
AL533_RS08765	COG1475	DNA binding
AL533_RS08770	COG1192	Involved in chromosome partitioning
AL533_RS08780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL533_RS08795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL533_RS08800	COG0191	fructose-bisphosphate aldolase activity
AL533_RS08820	COG0424	maF-like protein
AL533_RS08825	COG2850	peptidyl-arginine hydroxylation
AL533_RS08835	COG0640	Transcriptional regulator
AL533_RS08845	COG3619	membrane
AL533_RS08850	COG3122	Protein conserved in bacteria
AL533_RS08855	COG1132	(ABC) transporter
AL533_RS08875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL533_RS08880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL533_RS08890	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL533_RS08890	COG0506	proline dehydrogenase activity
AL533_RS08890	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL533_RS08895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL533_RS08910	COG3698	Phosphodiester glycosidase
AL533_RS08920	COG2353	YceI-like domain
AL533_RS08930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL533_RS08970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL533_RS08970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL533_RS08995	COG3539	Fimbrial protein
AL533_RS09000	COG3121	Chaperone
AL533_RS09030	COG0697	spore germination
AL533_RS09040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL533_RS09050	COG0583	DNA-binding transcription factor activity
AL533_RS09070	COG1309	transcriptional regulator
AL533_RS09085	COG1522	sequence-specific DNA binding
AL533_RS09095	COG1126	abc transporter atp-binding protein
AL533_RS09100	COG0765	amino acid transport
AL533_RS09105	COG0765	amino acid transport
AL533_RS09135	COG1464	Belongs to the NlpA lipoprotein family
AL533_RS09145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL533_RS09150	COG2011	ABC-type metal ion transport system permease component
AL533_RS09155	COG0012	GTP binding
AL533_RS09180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL533_RS09210	COG1280	lysine exporter protein (LysE YggA)
AL533_RS09220	COG0386	Belongs to the glutathione peroxidase family
AL533_RS09230	COG0436	Aminotransferase
AL533_RS09235	COG1301	dicarboxylic acid transport
AL533_RS09270	COG3634	alkyl hydroperoxide reductase activity
AL533_RS09285	COG0583	DNA-binding transcription factor activity
AL533_RS09290	COG0798	PFAM Bile acid sodium symporter
AL533_RS09295	COG0640	Transcriptional regulator
AL533_RS09315	COG0583	DNA-binding transcription factor activity
AL533_RS09325	COG1953	Uracil, thiamine, allantoin
AL533_RS09335	COG2175	clavaminate synthase activity
AL533_RS09340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL533_RS09345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL533_RS09350	COG4521	taurine ABC transporter
AL533_RS09360	COG0477	Major facilitator Superfamily
AL533_RS09385	COG1271	oxidase subunit
AL533_RS09390	COG1294	oxidase, subunit
AL533_RS09400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL533_RS09420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL533_RS09440	COG3052	prosthetic group binding
AL533_RS09445	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AL533_RS09470	COG1346	cytolysis
AL533_RS09480	COG0583	DNA-binding transcription factor activity
AL533_RS09485	COG0625	glutathione transferase activity
AL533_RS09490	COG0625	glutathione transferase activity
AL533_RS09495	COG0583	DNA-binding transcription factor activity
AL533_RS09510	COG1045	serine acetyltransferase
AL533_RS09515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL533_RS09520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL533_RS09525	COG1280	lysine exporter protein (LysE YggA)
AL533_RS09540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL533_RS09545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL533_RS09550	COG1126	abc transporter atp-binding protein
AL533_RS09555	COG0765	amino acid transport
AL533_RS09560	COG0765	amino acid transport
AL533_RS09580	COG0784	Response regulator, receiver
AL533_RS09580	COG2205	protein histidine kinase activity
AL533_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS09675	COG0583	DNA-binding transcription factor activity
AL533_RS09695	COG1309	transcriptional regulator
AL533_RS09700	COG1960	acyl-CoA dehydrogenase activity
AL533_RS09705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL533_RS09710	COG1024	Enoyl-CoA hydratase
AL533_RS09715	COG4770	biotin carboxylase activity
AL533_RS09725	COG0583	DNA-binding transcription factor activity
AL533_RS09740	COG1960	acyl-CoA dehydrogenase activity
AL533_RS09750	COG2814	Major facilitator Superfamily
AL533_RS09760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL533_RS09765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL533_RS09770	COG2814	Major facilitator Superfamily
AL533_RS09775	COG1960	acyl-CoA dehydrogenase activity
AL533_RS09780	COG1024	Enoyl-CoA hydratase
AL533_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS09790	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL533_RS09795	COG0183	Belongs to the thiolase family
AL533_RS09810	COG1280	lysine exporter protein (LysE YggA)
AL533_RS09815	COG2192	nodulation
AL533_RS09830	COG1024	Enoyl-CoA hydratase
AL533_RS09845	COG1960	acyl-CoA dehydrogenase activity
AL533_RS09850	COG2814	Major facilitator Superfamily
AL533_RS09855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL533_RS09860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL533_RS09860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL533_RS09875	COG3842	ATPase activity
AL533_RS09880	COG1840	ABC-type Fe3 transport system, periplasmic component
AL533_RS09890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL533_RS09895	COG1414	Transcriptional regulator
AL533_RS09905	COG0583	DNA-binding transcription factor activity
AL533_RS09910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL533_RS09915	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS09925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL533_RS09935	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS09940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL533_RS09945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL533_RS09950	COG2267	carboxylic ester hydrolase activity
AL533_RS09970	COG3038	cytochrome b561
AL533_RS09975	COG0753	catalase activity
AL533_RS09980	COG1733	regulation of RNA biosynthetic process
AL533_RS10025	COG2050	protein possibly involved in aromatic compounds catabolism
AL533_RS10035	COG3327	negative regulation of DNA-templated transcription, initiation
AL533_RS10040	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AL533_RS10045	COG0183	Belongs to the thiolase family
AL533_RS10050	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL533_RS10055	COG1024	Enoyl-CoA hydratase
AL533_RS10060	COG1024	Enoyl-CoA hydratase
AL533_RS10065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL533_RS10070	COG2151	metal-sulfur cluster biosynthetic enzyme
AL533_RS10075	COG3396	Phenylacetate-CoA oxygenase
AL533_RS10080	COG3460	Phenylacetate-CoA oxygenase
AL533_RS10085	COG3396	Phenylacetate-CoA oxygenase
AL533_RS10090	COG2030	dehydratase
AL533_RS10090	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS10095	COG1760	l-serine dehydratase
AL533_RS10105	COG0789	Transcriptional regulator
AL533_RS10115	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL533_RS10130	COG2807	transmembrane transport
AL533_RS10135	COG0590	tRNA wobble adenosine to inosine editing
AL533_RS10180	COG2885	chlorophyll binding
AL533_RS10240	COG0477	Major facilitator Superfamily
AL533_RS10255	COG1116	anion transmembrane transporter activity
AL533_RS10270	COG0864	Transcriptional regulator
AL533_RS10280	COG1733	regulation of RNA biosynthetic process
AL533_RS10285	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL533_RS10290	COG0439	Biotin carboxylase
AL533_RS10305	COG1063	alcohol dehydrogenase
AL533_RS10345	COG0038	chloride channel
AL533_RS10350	COG4770	biotin carboxylase activity
AL533_RS10370	COG1914	H( )-stimulated, divalent metal cation uptake system
AL533_RS10375	COG0583	DNA-binding transcription factor activity
AL533_RS10385	COG1595	DNA-templated transcription, initiation
AL533_RS10395	COG3220	belongs to the UPF0276 family
AL533_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS10435	COG2076	Multidrug Resistance protein
AL533_RS10450	COG3713	MltA-interacting MipA family protein
AL533_RS10455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL533_RS10545	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL533_RS10555	COG0789	Transcriptional regulator
AL533_RS10560	COG1278	Cold shock
AL533_RS10570	COG0626	cystathionine gamma-synthase activity
AL533_RS10580	COG1522	sequence-specific DNA binding
AL533_RS10595	COG4774	siderophore transport
AL533_RS10615	COG2814	Major facilitator Superfamily
AL533_RS10655	COG0583	DNA-binding transcription factor activity
AL533_RS10660	COG1960	acyl-CoA dehydrogenase activity
AL533_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS10695	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL533_RS10705	COG4122	O-methyltransferase activity
AL533_RS10735	COG1538	Outer membrane efflux protein
AL533_RS10740	COG1137	ATPase activity
AL533_RS10745	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL533_RS10755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL533_RS10760	COG0517	IMP dehydrogenase activity
AL533_RS10760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL533_RS10795	COG3328	transposase activity
AL533_RS10850	COG1280	lysine exporter protein (LysE YggA)
AL533_RS10880	COG1570	exodeoxyribonuclease VII activity
AL533_RS10965	COG2871	sodium ion transport
AL533_RS10975	COG0583	DNA-binding transcription factor activity
AL533_RS10980	COG4638	Rieske (2fe-2S)
AL533_RS10985	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL533_RS10990	COG0633	Ferredoxin
AL533_RS10990	COG0543	2 iron, 2 sulfur cluster binding
AL533_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS11000	COG3135	benzoate transporter
AL533_RS11005	COG2814	Major facilitator Superfamily
AL533_RS11020	COG1643	Atp-dependent helicase
AL533_RS11025	COG0450	alkyl hydroperoxide reductase
AL533_RS11045	COG3634	alkyl hydroperoxide reductase activity
AL533_RS11065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL533_RS11070	COG0625	glutathione transferase activity
AL533_RS11080	COG2885	chlorophyll binding
AL533_RS11115	COG0542	response to heat
AL533_RS11130	COG1765	OsmC-like protein
AL533_RS11140	COG0667	Aldo Keto reductase
AL533_RS11155	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL533_RS11175	COG0527	aspartate kinase activity
AL533_RS11185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL533_RS11195	COG3038	cytochrome b561
AL533_RS11200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL533_RS11205	COG2252	PERMEase
AL533_RS11215	COG2072	flavoprotein involved in K transport
AL533_RS11220	COG0300	oxidoreductase activity
AL533_RS11230	COG1741	Belongs to the pirin family
AL533_RS11235	COG1309	transcriptional regulator
AL533_RS11250	COG2072	flavoprotein involved in K transport
AL533_RS11255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AL533_RS11285	COG1944	ATP diphosphatase activity
AL533_RS11305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL533_RS11320	COG2814	Major facilitator Superfamily
AL533_RS11325	COG1024	Enoyl-CoA hydratase
AL533_RS11330	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS11340	COG1960	acyl-CoA dehydrogenase activity
AL533_RS11365	COG0697	spore germination
AL533_RS11380	COG1113	amino acid transport
AL533_RS11410	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS11430	COG0531	amino acid
AL533_RS11440	COG1113	amino acid transport
AL533_RS11555	COG2059	Chromate
AL533_RS11565	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL533_RS11575	COG1230	cation diffusion facilitator family transporter
AL533_RS11590	COG2814	Major facilitator Superfamily
AL533_RS11635	COG3328	transposase activity
AL533_RS11705	COG0582	viral genome integration into host DNA
AL533_RS11715	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL533_RS11715	COG1902	pentaerythritol trinitrate reductase activity
AL533_RS11730	COG5001	Diguanylate cyclase
AL533_RS11730	COG3706	GGDEF domain
AL533_RS11730	COG4251	negative regulation of phosphorylation
AL533_RS11730	COG2203	Gaf domain
AL533_RS11740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL533_RS11765	COG4172	Belongs to the ABC transporter superfamily
AL533_RS11770	COG4239	(ABC) transporter, permease
AL533_RS11775	COG4174	ABC transporter (Permease)
AL533_RS11785	COG0741	lytic transglycosylase activity
AL533_RS11785	COG1388	LysM domain
AL533_RS11785	COG0741	lytic transglycosylase activity
AL533_RS11785	COG1388	LysM domain
AL533_RS11825	COG0583	DNA-binding transcription factor activity
AL533_RS11830	COG1279	arginine transmembrane transporter activity
AL533_RS11850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL533_RS11855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL533_RS11860	COG0006	proline dipeptidase activity
AL533_RS11895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL533_RS11935	COG3384	dioxygenase
AL533_RS11945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL533_RS11950	COG2878	Part of a membrane complex involved in electron transport
AL533_RS11955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL533_RS11980	COG0768	penicillin binding
AL533_RS11985	COG0742	ribosomal rna small subunit methyltransferase
AL533_RS12005	COG0830	nickel cation binding
AL533_RS12015	COG0804	urea catabolic process
AL533_RS12055	COG1253	flavin adenine dinucleotide binding
AL533_RS12120	COG1773	rubredoxin
AL533_RS12125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL533_RS12135	COG0583	DNA-binding transcription factor activity
AL533_RS12160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL533_RS12165	COG4181	ATPase activity
AL533_RS12210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL533_RS12230	COG0306	phosphate transporter
AL533_RS12260	COG2223	nitrite transmembrane transporter activity
AL533_RS12265	COG0662	Cupin 2, conserved barrel domain protein
AL533_RS12265	COG2207	Transcriptional regulator
AL533_RS12270	COG2066	Belongs to the glutaminase family
AL533_RS12275	COG0242	peptide deformylase activity
AL533_RS12280	COG0477	Major facilitator Superfamily
AL533_RS12290	COG0028	Belongs to the TPP enzyme family
AL533_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS12310	COG2267	carboxylic ester hydrolase activity
AL533_RS12320	COG2271	Major facilitator Superfamily
AL533_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS12355	COG1414	Transcriptional regulator
AL533_RS12380	COG1024	Enoyl-CoA hydratase
AL533_RS12390	COG1215	transferase activity, transferring glycosyl groups
AL533_RS12395	COG1649	PFAM Uncharacterised BCR, COG1649
AL533_RS12395	COG0726	polysaccharide deacetylase
AL533_RS12405	COG4681	YaeQ
AL533_RS12415	COG0523	cobalamin synthesis protein
AL533_RS12425	COG1607	acyl-coa hydrolase
AL533_RS12435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL533_RS12440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL533_RS12445	COG1309	transcriptional regulator
AL533_RS12470	COG2040	homocysteine
AL533_RS12475	COG0531	amino acid
AL533_RS12495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL533_RS12500	COG0477	Major facilitator Superfamily
AL533_RS12510	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AL533_RS12565	COG3177	Filamentation induced by cAMP protein fic
AL533_RS12570	COG3328	transposase activity
AL533_RS12585	COG1360	Flagellar Motor Protein
AL533_RS12600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL533_RS12610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL533_RS12625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL533_RS12635	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL533_RS12655	COG0500	methyltransferase
AL533_RS12655	COG3615	Tellurite resistance protein tehB
AL533_RS12720	COG0582	viral genome integration into host DNA
AL533_RS12730	COG0405	Gamma-glutamyltransferase
AL533_RS12735	COG2814	Major facilitator Superfamily
AL533_RS12745	COG2050	protein possibly involved in aromatic compounds catabolism
AL533_RS12760	COG1090	epimerase
AL533_RS12780	COG0420	3'-5' exonuclease activity
AL533_RS12790	COG1968	undecaprenyl-diphosphatase activity
AL533_RS12810	COG0735	belongs to the Fur family
AL533_RS12815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL533_RS12840	COG0121	glutamine amidotransferase
AL533_RS12855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL533_RS12865	COG0210	DNA helicase
AL533_RS12870	COG2885	chlorophyll binding
AL533_RS12875	COG0204	Acyl-transferase
AL533_RS12890	COG2894	cell division
AL533_RS12905	COG1280	lysine exporter protein (LysE YggA)
AL533_RS12910	COG1674	ftsk spoiiie
AL533_RS12915	COG0492	ferredoxin-NADP+ reductase activity
AL533_RS12920	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL533_RS12930	COG0456	acetyltransferase
AL533_RS12960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL533_RS12975	COG1981	membrane
AL533_RS12990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL533_RS12990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL533_RS13010	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS13015	COG4638	Rieske (2fe-2S)
AL533_RS13020	COG0657	acetylesterase activity
AL533_RS13030	COG0473	3-isopropylmalate dehydrogenase activity
AL533_RS13035	COG0583	DNA-binding transcription factor activity
AL533_RS13055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL533_RS13065	COG0582	viral genome integration into host DNA
AL533_RS13235	COG0358	DNA primase activity
AL533_RS13250	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL533_RS13280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL533_RS13310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL533_RS13320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL533_RS13320	COG0351	phosphomethylpyrimidine kinase
AL533_RS13320	COG0352	thiamine-phosphate diphosphorylase activity
AL533_RS13325	COG1652	LysM domain
AL533_RS13350	COG1399	metal-binding, possibly nucleic acid-binding protein
AL533_RS13355	COG3101	peptidyl-lysine hydroxylation
AL533_RS13360	COG0009	L-threonylcarbamoyladenylate synthase
AL533_RS13365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL533_RS13370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL533_RS13385	COG4106	trans-aconitate 2-methyltransferase activity
AL533_RS13400	COG2226	methyltransferase
AL533_RS13400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL533_RS13400	COG0596	Alpha beta hydrolase
AL533_RS13405	COG1877	trehalose-phosphatase activity
AL533_RS13410	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AL533_RS13415	COG2223	nitrite transmembrane transporter activity
AL533_RS13440	COG1196	nuclear chromosome segregation
AL533_RS13450	COG0730	response to heat
AL533_RS13465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL533_RS13530	COG0489	protein tyrosine kinase activity
AL533_RS13545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL533_RS13545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL533_RS13580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL533_RS13585	COG2081	HI0933 family
AL533_RS13595	COG0668	transmembrane transport
AL533_RS13615	COG0583	DNA-binding transcription factor activity
AL533_RS13640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL533_RS13645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL533_RS13675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AL533_RS13700	COG3706	GGDEF domain
AL533_RS13715	COG0745	RESPONSE REGULATOR receiver
AL533_RS13735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL533_RS13740	COG0384	phenazine biosynthesis protein PhzF
AL533_RS13765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL533_RS13780	COG0583	DNA-binding transcription factor activity
AL533_RS13790	COG0583	DNA-binding transcription factor activity
AL533_RS13810	COG0583	DNA-binding transcription factor activity
AL533_RS13815	COG1053	succinate dehydrogenase
AL533_RS13830	COG1309	transcriptional regulator
AL533_RS13835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL533_RS13840	COG2814	Major facilitator Superfamily
AL533_RS13845	COG1960	acyl-CoA dehydrogenase activity
AL533_RS13850	COG0583	DNA-binding transcription factor activity
AL533_RS13855	COG1063	alcohol dehydrogenase
AL533_RS13885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL533_RS13890	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL533_RS13895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL533_RS13915	COG2132	Multicopper oxidase
AL533_RS13925	COG0561	phosphatase activity
AL533_RS13930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL533_RS13955	COG1214	PFAM Peptidase M22, glycoprotease
AL533_RS14025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL533_RS14030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL533_RS14035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL533_RS14095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL533_RS14105	COG1846	Transcriptional regulator
AL533_RS14110	COG1764	response to oxidative stress
AL533_RS14150	COG0037	tRNA processing
AL533_RS14160	COG0248	Ppx GppA phosphatase
AL533_RS14190	COG0072	phenylalanine-tRNA ligase activity
AL533_RS14220	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL533_RS14230	COG1238	metal cluster binding
AL533_RS14235	COG0625	glutathione transferase activity
AL533_RS14250	COG0318	PFAM AMP-dependent synthetase and ligase
AL533_RS14255	COG3028	Belongs to the UPF0307 family
AL533_RS14260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL533_RS14280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL533_RS14285	COG0617	tRNA 3'-terminal CCA addition
AL533_RS14290	COG1555	photosystem II stabilization
AL533_RS14295	COG3956	TIGRFAM MazG family protein
AL533_RS14305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL533_RS14325	COG5002	protein histidine kinase activity
AL533_RS14325	COG0784	Response regulator, receiver
AL533_RS14325	COG2205	protein histidine kinase activity
AL533_RS14330	COG1024	Enoyl-CoA hydratase
AL533_RS14335	COG2084	Dehydrogenase
AL533_RS14340	COG3622	Belongs to the hyi family
AL533_RS14370	COG0697	spore germination
AL533_RS14380	COG2814	Major facilitator Superfamily
AL533_RS14405	COG2072	flavoprotein involved in K transport
AL533_RS14410	COG0492	ferredoxin-NADP+ reductase activity
AL533_RS14415	COG0431	NADPH-dependent FMN reductase
AL533_RS14420	COG0798	PFAM Bile acid sodium symporter
AL533_RS14430	COG0640	Transcriptional regulator
AL533_RS14460	COG3328	transposase activity
AL533_RS14475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL533_RS14500	COG2132	Multicopper oxidase
AL533_RS14515	COG2205	protein histidine kinase activity
AL533_RS14595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL533_RS14615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL533_RS14625	COG0084	hydrolase, TatD family'
AL533_RS14640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL533_RS14650	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL533_RS14665	COG0732	type I restriction modification DNA specificity domain
AL533_RS14675	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL533_RS14775	COG0440	acetolactate synthase activity
AL533_RS14780	COG0028	Belongs to the TPP enzyme family
AL533_RS14805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS14810	COG1136	(ABC) transporter
AL533_RS14810	COG0577	efflux transmembrane transporter activity
AL533_RS14815	COG1538	Outer membrane efflux protein
AL533_RS14830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL533_RS14835	COG1162	GTPase activity
AL533_RS14845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL533_RS14865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL533_RS14885	COG1426	Protein conserved in bacteria
AL533_RS14920	COG0793	Belongs to the peptidase S41A family
AL533_RS14945	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS14950	COG3265	gluconokinase activity
AL533_RS14960	COG0800	Aldolase
AL533_RS14970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL533_RS14975	COG0280	phosphate acetyltransferase
AL533_RS14975	COG0857	belongs to the CobB CobQ family
AL533_RS14980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL533_RS14980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL533_RS14990	COG3328	transposase activity
AL533_RS15005	COG0740	serine-type endopeptidase activity
AL533_RS15015	COG4774	siderophore transport
AL533_RS15025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL533_RS15035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL533_RS15035	COG2813	Specifically methylates the guanine in position
AL533_RS15140	COG0788	formyltetrahydrofolate deformylase activity
AL533_RS15165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL533_RS15165	COG4651	solute:proton antiporter activity
AL533_RS15185	COG0724	RNA recognition motif
AL533_RS15190	COG0210	DNA helicase
AL533_RS15220	COG1733	regulation of RNA biosynthetic process
AL533_RS15230	COG2900	Belongs to the SlyX family
AL533_RS15235	COG0488	(ABC) transporter
AL533_RS15245	COG1280	lysine exporter protein (LysE YggA)
AL533_RS15250	COG1560	Kdo2-lipid A biosynthetic process
AL533_RS15260	COG1301	dicarboxylic acid transport
AL533_RS15315	COG0473	3-isopropylmalate dehydrogenase activity
AL533_RS15340	COG0583	DNA-binding transcription factor activity
AL533_RS15385	COG0583	DNA-binding transcription factor activity
AL533_RS15395	COG0625	glutathione transferase activity
AL533_RS15400	COG2378	regulation of single-species biofilm formation
AL533_RS15420	COG1530	ribonuclease E activity
AL533_RS15425	COG0318	PFAM AMP-dependent synthetase and ligase
AL533_RS15440	COG0583	DNA-binding transcription factor activity
AL533_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS15450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL533_RS15460	COG0534	Mate efflux family protein
AL533_RS15475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL533_RS15500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL533_RS15500	COG0493	'glutamate synthase
AL533_RS15510	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL533_RS15515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL533_RS15530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL533_RS15540	COG0644	oxidoreductase
AL533_RS15540	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AL533_RS15555	COG4535	Mg2 and Co2 transporter CorC
AL533_RS15565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL533_RS15585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL533_RS15590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL533_RS15590	COG0475	glutathione-regulated potassium exporter activity
AL533_RS15595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL533_RS15605	COG0484	heat shock protein binding
AL533_RS15610	COG0789	Transcriptional regulator
AL533_RS15615	COG0598	Magnesium transport protein CorA
AL533_RS15620	COG1185	polyribonucleotide nucleotidyltransferase activity
AL533_RS15630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL533_RS15635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL533_RS15640	COG1074	ATP-dependent DNA helicase activity
AL533_RS15645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL533_RS15670	COG2226	methyltransferase
AL533_RS15680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL533_RS15685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL533_RS15695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL533_RS15710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL533_RS15710	COG2111	Na H antiporter
AL533_RS15715	COG1006	Multisubunit Na H antiporter MnhC subunit
AL533_RS15720	COG0651	ATP synthesis coupled electron transport
AL533_RS15725	COG1863	multisubunit Na H antiporter MnhE subunit
AL533_RS15730	COG2212	antiporter activity
AL533_RS15735	COG1320	monovalent cation:proton antiporter activity
AL533_RS15740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL533_RS15750	COG0195	Participates in both transcription termination and antitermination
AL533_RS15800	COG0237	dephospho-CoA kinase activity
AL533_RS15810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL533_RS15825	COG0497	DNA recombination
AL533_RS15835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL533_RS15850	COG1289	transmembrane transporter activity
AL533_RS15865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL533_RS15865	COG2169	Transcriptional regulator
AL533_RS15870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL533_RS15940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AL533_RS15955	COG0326	Molecular chaperone. Has ATPase activity
AL533_RS15970	COG2056	Na+-H+ antiporter family
AL533_RS15975	COG0596	Alpha beta hydrolase
AL533_RS16075	COG0546	phosphoglycolate phosphatase activity
AL533_RS16080	COG1716	ATPase activity
AL533_RS16125	COG0181	hydroxymethylbilane synthase activity
AL533_RS16135	COG3275	phosphorelay sensor kinase activity
AL533_RS16155	COG1538	Outer membrane efflux protein
AL533_RS16160	COG0697	spore germination
AL533_RS16180	COG0494	nUDIX hydrolase
AL533_RS16185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL533_RS16190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL533_RS16195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL533_RS16200	COG0772	Belongs to the SEDS family
AL533_RS16225	COG4974	Belongs to the 'phage' integrase family
AL533_RS16230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL533_RS16240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL533_RS16250	COG2197	response regulator
AL533_RS16265	COG0793	Belongs to the peptidase S41A family
AL533_RS16270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL533_RS16275	COG0795	lipopolysaccharide-transporting ATPase activity
AL533_RS16315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL533_RS16315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL533_RS16325	COG0004	ammonium transporteR
AL533_RS16330	COG0347	Belongs to the P(II) protein family
AL533_RS16340	COG0606	chelatase, subunit chli
AL533_RS16345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL533_RS16350	COG0235	Class ii aldolase
AL533_RS16355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL533_RS16370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL533_RS16385	COG0318	PFAM AMP-dependent synthetase and ligase
AL533_RS16395	COG0477	Major facilitator Superfamily
AL533_RS16400	COG2860	membrane
AL533_RS16410	COG1253	flavin adenine dinucleotide binding
AL533_RS16420	COG2814	Major facilitator Superfamily
AL533_RS16430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL533_RS16465	COG0655	NAD(P)H dehydrogenase (quinone) activity
AL533_RS16480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL533_RS16515	COG1309	transcriptional regulator
AL533_RS16550	COG0758	DNA mediated transformation
AL533_RS16560	COG0697	spore germination
AL533_RS16565	COG1309	transcriptional regulator
AL533_RS16580	COG0386	Belongs to the glutathione peroxidase family
AL533_RS16590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL533_RS16645	COG1121	(ABC) transporter
AL533_RS16650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL533_RS16655	COG1280	lysine exporter protein (LysE YggA)
AL533_RS16660	COG2837	iron assimilation
AL533_RS16665	COG0281	malic enzyme
AL533_RS16705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL533_RS16710	COG0519	Catalyzes the synthesis of GMP from XMP
AL533_RS16710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL533_RS16715	COG4399	Belongs to the UPF0754 family
AL533_RS16720	COG2259	Doxx family
AL533_RS16725	COG0586	Pfam SNARE associated Golgi protein
AL533_RS16740	COG1192	Involved in chromosome partitioning
AL533_RS16750	COG0271	Belongs to the BolA IbaG family
AL533_RS16795	COG1960	acyl-CoA dehydrogenase activity
AL533_RS16800	COG0318	PFAM AMP-dependent synthetase and ligase
AL533_RS16815	COG3916	Acyl-homoserine-lactone synthase
AL533_RS16820	COG0477	Major facilitator Superfamily
AL533_RS16825	COG1024	Enoyl-CoA hydratase
AL533_RS16830	COG1024	Enoyl-CoA hydratase
AL533_RS16835	COG1960	acyl-CoA dehydrogenase activity
AL533_RS16840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL533_RS16860	COG1113	amino acid transport
AL533_RS16865	COG1113	amino acid transport
AL533_RS16870	COG0251	oxidation-reduction process
AL533_RS16910	COG0564	pseudouridine synthase activity
AL533_RS16960	COG1403	HNH endonuclease
AL533_RS16965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL533_RS16980	COG1802	Transcriptional regulator
AL533_RS16990	COG1448	Aminotransferase
AL533_RS16995	COG0277	FAD linked oxidase domain protein
AL533_RS17005	COG2186	Transcriptional regulator
AL533_RS17015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL533_RS17025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL533_RS17040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL533_RS17045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL533_RS17055	COG0438	transferase activity, transferring glycosyl groups
AL533_RS17065	COG0438	transferase activity, transferring glycosyl groups
AL533_RS17070	COG0463	Glycosyl transferase, family 2
AL533_RS17070	COG1216	Glycosyl transferase, family 2
AL533_RS17090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL533_RS17100	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL533_RS17105	COG1596	polysaccharide export
AL533_RS17130	COG0728	peptidoglycan biosynthetic process
AL533_RS17135	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL533_RS17195	COG0546	phosphoglycolate phosphatase activity
AL533_RS17200	COG1028	Short-chain dehydrogenase reductase Sdr
AL533_RS17215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL533_RS17215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL533_RS17220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL533_RS17225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL533_RS17230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL533_RS17235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL533_RS17240	COG1116	anion transmembrane transporter activity
AL533_RS17245	COG1309	transcriptional regulator
AL533_RS17250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL533_RS17260	COG0196	riboflavin kinase activity
AL533_RS17265	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL533_RS17275	COG1047	Peptidyl-prolyl cis-trans
AL533_RS17315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL533_RS17320	COG0657	acetylesterase activity
AL533_RS17370	COG2951	lytic endotransglycosylase activity
AL533_RS17375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL533_RS17395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL533_RS17405	COG0671	phosphoesterase, PA-phosphatase related
AL533_RS17410	COG0861	Integral membrane protein TerC family
AL533_RS17420	COG0754	glutathionylspermidine amidase activity
AL533_RS17430	COG0402	S-adenosylhomocysteine deaminase activity
AL533_RS17445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL533_RS17465	COG0706	membrane insertase activity
AL533_RS17490	COG0592	DNA-directed DNA polymerase activity
AL533_RS17500	COG0187	DNA topoisomerase II activity
AL533_RS17510	COG0586	Pfam SNARE associated Golgi protein
AL533_RS17515	COG0488	(ABC) transporter
AL533_RS17540	COG0596	Alpha beta hydrolase
AL533_RS17545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL533_RS17550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL533_RS17590	COG0733	neurotransmitter:sodium symporter activity
AL533_RS17630	COG2233	PERMEase
AL533_RS17645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL533_RS17680	COG2814	Major facilitator Superfamily
AL533_RS17685	COG0656	L-ascorbic acid biosynthetic process
AL533_RS17690	COG0583	DNA-binding transcription factor activity
AL533_RS17705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL533_RS17710	COG1064	alcohol dehydrogenase
AL533_RS17715	COG2818	Glycosylase
AL533_RS17730	COG1194	a g-specific adenine glycosylase
AL533_RS17745	COG5487	UPF0391 membrane protein
AL533_RS17750	COG2983	Belongs to the UPF0260 family
AL533_RS17755	COG2133	pyrroloquinoline quinone binding
AL533_RS17760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL533_RS17765	COG2116	formate transmembrane transporter activity
AL533_RS17785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL533_RS17790	COG1335	isochorismatase
AL533_RS17795	COG0385	Bile acid
AL533_RS17800	COG0534	Mate efflux family protein
AL533_RS17805	COG1683	Conserved Protein
AL533_RS17825	COG0625	glutathione transferase activity
AL533_RS17835	COG1113	amino acid transport
AL533_RS17845	COG0523	cobalamin synthesis protein
AL533_RS17855	COG2188	Transcriptional regulator
AL533_RS17885	COG0010	Belongs to the arginase family
AL533_RS17900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL533_RS17910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL533_RS17920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL533_RS17925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL533_RS18020	COG0534	Mate efflux family protein
AL533_RS18030	COG0154	amidase activity
AL533_RS18040	COG0436	Aminotransferase
AL533_RS18045	COG2733	membrane
AL533_RS18060	COG2918	glutathione biosynthetic process
AL533_RS18110	COG3150	esterase
AL533_RS18120	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AL533_RS18130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL533_RS18140	COG2233	PERMEase
AL533_RS18145	COG2351	hydroxyisourate hydrolase activity
AL533_RS18180	COG3706	GGDEF domain
AL533_RS18195	COG1393	Belongs to the ArsC family
AL533_RS18200	COG0708	Exodeoxyribonuclease III
AL533_RS18220	COG0189	ligase activity
AL533_RS18245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL533_RS18255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL533_RS18270	COG4942	peptidase
AL533_RS18280	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL533_RS18290	COG2119	membrane
AL533_RS18295	COG0426	domain, Protein
AL533_RS18295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL533_RS18320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL533_RS18340	COG1902	pentaerythritol trinitrate reductase activity
AL533_RS18345	COG1519	Transferase
AL533_RS18350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL533_RS18355	COG0668	transmembrane transport
AL533_RS18365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL533_RS18370	COG1335	isochorismatase
AL533_RS18375	COG1522	sequence-specific DNA binding
AL533_RS18400	COG2198	Histidine kinase
AL533_RS18400	COG2205	protein histidine kinase activity
AL533_RS18400	COG0784	Response regulator, receiver
AL533_RS18405	COG3162	membrane
AL533_RS18410	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL533_RS18420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL533_RS18440	COG1309	transcriptional regulator
AL533_RS18460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL533_RS18460	COG0352	thiamine-phosphate diphosphorylase activity
AL533_RS18460	COG0351	phosphomethylpyrimidine kinase
AL533_RS18470	COG2814	Major facilitator Superfamily
AL533_RS18485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL533_RS18495	COG1113	amino acid transport
AL533_RS18505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL533_RS18510	COG1012	belongs to the aldehyde dehydrogenase family
AL533_RS18520	COG1335	isochorismatase
AL533_RS18555	COG2814	Major facilitator Superfamily
AL533_RS18560	COG0583	DNA-binding transcription factor activity
AL533_RS18580	COG0667	Aldo Keto reductase
AL533_RS18615	COG1733	regulation of RNA biosynthetic process
AL533_RS18620	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL533_RS18690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL533_RS18715	COG4619	ABC transporter
AL533_RS18735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL533_RS18765	COG0427	acetyl-CoA hydrolase
AL533_RS18795	COG0659	secondary active sulfate transmembrane transporter activity
AL533_RS18800	COG4221	oxidoreductase activity
AL533_RS18805	COG2873	o-acetylhomoserine
AL533_RS18810	COG0028	Belongs to the TPP enzyme family
AL533_RS18815	COG0488	(ABC) transporter
AL533_RS18880	COG0833	amino acid
AL533_RS18905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL533_RS18925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL533_RS18930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL533_RS18945	COG2226	methyltransferase
AL533_RS18995	COG0070	glutamate synthase
AL533_RS18995	COG0067	glutamate synthase
AL533_RS18995	COG0069	glutamate synthase activity
AL533_RS19000	COG0493	'glutamate synthase
AL533_RS19010	COG1704	LemA family
AL533_RS19015	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AL533_RS19035	COG3307	-O-antigen
AL533_RS19055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL533_RS19070	COG0194	GDP metabolic process
AL533_RS19120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL533_RS19140	COG5380	lipid catabolic process
AL533_RS19145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL533_RS19160	COG5006	permease, DMT superfamily
AL533_RS19165	COG5006	permease, DMT superfamily
AL533_RS19170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL533_RS19175	COG0277	FAD linked oxidase domain protein
AL533_RS19190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL533_RS19195	COG2249	NAD(P)H dehydrogenase (quinone) activity