locus-tag	class	description
FDQ49_RS00015	COG0583	DNA-binding transcription factor activity
FDQ49_RS00020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDQ49_RS00030	COG2084	Dehydrogenase
FDQ49_RS00040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDQ49_RS00045	COG1120	ATPase activity
FDQ49_RS00065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDQ49_RS00085	COG2314	TM2 domain
FDQ49_RS00145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDQ49_RS00225	COG1073	alpha beta
FDQ49_RS00250	COG2259	Doxx family
FDQ49_RS00255	COG0583	DNA-binding transcription factor activity
FDQ49_RS00260	COG2205	protein histidine kinase activity
FDQ49_RS00265	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS00270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS00275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDQ49_RS00280	COG1538	Outer membrane efflux protein
FDQ49_RS00290	COG2175	clavaminate synthase activity
FDQ49_RS00295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDQ49_RS00310	COG0667	Aldo Keto reductase
FDQ49_RS00315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDQ49_RS00330	COG2175	clavaminate synthase activity
FDQ49_RS00360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS00365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDQ49_RS00370	COG4771	TonB-dependent receptor
FDQ49_RS00400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDQ49_RS00405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDQ49_RS00410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS00415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS00430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDQ49_RS00465	COG1132	(ABC) transporter
FDQ49_RS00470	COG1132	(ABC) transporter
FDQ49_RS00490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDQ49_RS00495	COG0601	transmembrane transport
FDQ49_RS00525	COG3539	Fimbrial protein
FDQ49_RS00550	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDQ49_RS00560	COG0753	catalase activity
FDQ49_RS00575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDQ49_RS00640	COG4771	TonB-dependent receptor
FDQ49_RS00645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDQ49_RS00650	COG3433	isochorismatase activity
FDQ49_RS00650	COG1535	isochorismatase
FDQ49_RS00655	COG1021	2,3-dihydroxybenzoate-AMP ligase
FDQ49_RS00660	COG1169	isochorismate synthase
FDQ49_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS00675	COG3251	PFAM MbtH domain protein
FDQ49_RS00680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDQ49_RS00710	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDQ49_RS00715	COG4149	molybdate abc transporter
FDQ49_RS00720	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDQ49_RS00730	COG4638	Rieske (2fe-2S)
FDQ49_RS00735	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDQ49_RS00740	COG0543	2 iron, 2 sulfur cluster binding
FDQ49_RS00740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDQ49_RS00755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDQ49_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS00780	COG2207	Transcriptional regulator
FDQ49_RS00785	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS00790	COG2610	gluconate transmembrane transporter activity
FDQ49_RS00795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDQ49_RS00820	COG2814	Major facilitator Superfamily
FDQ49_RS00840	COG0583	DNA-binding transcription factor activity
FDQ49_RS00855	COG2031	fatty acid transporter
FDQ49_RS00860	COG0183	Belongs to the thiolase family
FDQ49_RS00865	COG0583	DNA-binding transcription factor activity
FDQ49_RS00870	COG0583	DNA-binding transcription factor activity
FDQ49_RS00885	COG1027	Aspartate ammonia-lyase
FDQ49_RS00895	COG0477	Major facilitator Superfamily
FDQ49_RS00915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS00920	COG4521	taurine ABC transporter
FDQ49_RS00935	COG2188	Transcriptional regulator
FDQ49_RS00945	COG2207	Transcriptional regulator
FDQ49_RS00945	COG3708	Transcriptional regulator
FDQ49_RS00960	COG0730	response to heat
FDQ49_RS00970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDQ49_RS00970	COG3453	Protein conserved in bacteria
FDQ49_RS00980	COG3781	membrane
FDQ49_RS00985	COG1063	alcohol dehydrogenase
FDQ49_RS00995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDQ49_RS01000	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDQ49_RS01005	COG0022	dehydrogenase e1 component
FDQ49_RS01010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDQ49_RS01015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDQ49_RS01045	COG0133	tryptophan synthase activity
FDQ49_RS01055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDQ49_RS01090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDQ49_RS01115	COG2226	methyltransferase
FDQ49_RS01170	COG0842	Transport permease protein
FDQ49_RS01175	COG0842	Transport permease protein
FDQ49_RS01180	COG1131	(ABC) transporter
FDQ49_RS01195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDQ49_RS01200	COG4773	Receptor
FDQ49_RS01220	COG0730	response to heat
FDQ49_RS01225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDQ49_RS01235	COG4772	TonB-dependent receptor
FDQ49_RS01250	COG0406	alpha-ribazole phosphatase activity
FDQ49_RS01255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDQ49_RS01280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDQ49_RS01295	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS01300	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS01305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDQ49_RS01310	COG2207	Transcriptional regulator
FDQ49_RS01315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDQ49_RS01320	COG0776	regulation of translation
FDQ49_RS01345	COG0822	iron-sulfur transferase activity
FDQ49_RS01350	COG0316	Belongs to the HesB IscA family
FDQ49_RS01380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDQ49_RS01400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDQ49_RS01405	COG0702	epimerase
FDQ49_RS01435	COG4172	Belongs to the ABC transporter superfamily
FDQ49_RS01440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDQ49_RS01445	COG0601	transmembrane transport
FDQ49_RS01450	COG0339	signal peptide processing
FDQ49_RS01475	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FDQ49_RS01500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDQ49_RS01505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDQ49_RS01520	COG2431	L-lysine efflux transmembrane transporter activity
FDQ49_RS01535	COG0776	regulation of translation
FDQ49_RS01600	COG0084	hydrolase, TatD family'
FDQ49_RS01620	COG1663	tetraacyldisaccharide 4'-kinase activity
FDQ49_RS01625	COG1132	(ABC) transporter
FDQ49_RS01635	COG0811	peptide transport
FDQ49_RS01640	COG1475	DNA binding
FDQ49_RS01645	COG1192	Involved in chromosome partitioning
FDQ49_RS01655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDQ49_RS01670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDQ49_RS01675	COG0191	fructose-bisphosphate aldolase activity
FDQ49_RS01695	COG0424	maF-like protein
FDQ49_RS01700	COG2850	peptidyl-arginine hydroxylation
FDQ49_RS01710	COG0640	Transcriptional regulator
FDQ49_RS01720	COG3619	membrane
FDQ49_RS01725	COG3122	Protein conserved in bacteria
FDQ49_RS01730	COG1132	(ABC) transporter
FDQ49_RS01750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDQ49_RS01755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDQ49_RS01765	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDQ49_RS01765	COG0506	proline dehydrogenase activity
FDQ49_RS01765	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDQ49_RS01770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FDQ49_RS01785	COG3698	Phosphodiester glycosidase
FDQ49_RS01795	COG2353	YceI-like domain
FDQ49_RS01815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDQ49_RS01855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDQ49_RS01855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDQ49_RS01880	COG3539	Fimbrial protein
FDQ49_RS01885	COG3121	Chaperone
FDQ49_RS01925	COG0697	spore germination
FDQ49_RS01935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDQ49_RS01945	COG0583	DNA-binding transcription factor activity
FDQ49_RS01965	COG1309	transcriptional regulator
FDQ49_RS01980	COG1522	sequence-specific DNA binding
FDQ49_RS01990	COG1126	abc transporter atp-binding protein
FDQ49_RS01995	COG0765	amino acid transport
FDQ49_RS02000	COG0765	amino acid transport
FDQ49_RS02030	COG1464	Belongs to the NlpA lipoprotein family
FDQ49_RS02040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDQ49_RS02045	COG2011	ABC-type metal ion transport system permease component
FDQ49_RS02050	COG0012	GTP binding
FDQ49_RS02075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDQ49_RS02105	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS02115	COG0386	Belongs to the glutathione peroxidase family
FDQ49_RS02125	COG0436	Aminotransferase
FDQ49_RS02130	COG1301	dicarboxylic acid transport
FDQ49_RS02165	COG3634	alkyl hydroperoxide reductase activity
FDQ49_RS02180	COG0583	DNA-binding transcription factor activity
FDQ49_RS02185	COG0798	PFAM Bile acid sodium symporter
FDQ49_RS02190	COG0640	Transcriptional regulator
FDQ49_RS02205	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FDQ49_RS02215	COG0583	DNA-binding transcription factor activity
FDQ49_RS02225	COG1953	Uracil, thiamine, allantoin
FDQ49_RS02235	COG2175	clavaminate synthase activity
FDQ49_RS02240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS02245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FDQ49_RS02250	COG4521	taurine ABC transporter
FDQ49_RS02260	COG0477	Major facilitator Superfamily
FDQ49_RS02285	COG1271	oxidase subunit
FDQ49_RS02290	COG1294	oxidase, subunit
FDQ49_RS02300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDQ49_RS02305	COG2814	Major facilitator Superfamily
FDQ49_RS02310	COG0300	oxidoreductase activity
FDQ49_RS02335	COG1346	cytolysis
FDQ49_RS02345	COG0583	DNA-binding transcription factor activity
FDQ49_RS02350	COG0625	glutathione transferase activity
FDQ49_RS02355	COG0625	glutathione transferase activity
FDQ49_RS02360	COG0583	DNA-binding transcription factor activity
FDQ49_RS02375	COG1045	serine acetyltransferase
FDQ49_RS02380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDQ49_RS02385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDQ49_RS02390	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS02405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDQ49_RS02410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDQ49_RS02415	COG1126	abc transporter atp-binding protein
FDQ49_RS02420	COG0765	amino acid transport
FDQ49_RS02425	COG0765	amino acid transport
FDQ49_RS02465	COG0784	Response regulator, receiver
FDQ49_RS02465	COG2205	protein histidine kinase activity
FDQ49_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS02560	COG0583	DNA-binding transcription factor activity
FDQ49_RS02580	COG0318	PFAM AMP-dependent synthetase and ligase
FDQ49_RS02585	COG1309	transcriptional regulator
FDQ49_RS02590	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS02595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDQ49_RS02600	COG1024	Enoyl-CoA hydratase
FDQ49_RS02605	COG4770	biotin carboxylase activity
FDQ49_RS02615	COG0583	DNA-binding transcription factor activity
FDQ49_RS02630	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS02640	COG2814	Major facilitator Superfamily
FDQ49_RS02650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDQ49_RS02655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDQ49_RS02660	COG2814	Major facilitator Superfamily
FDQ49_RS02665	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS02670	COG1024	Enoyl-CoA hydratase
FDQ49_RS02675	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS02680	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDQ49_RS02685	COG0183	Belongs to the thiolase family
FDQ49_RS02695	COG2814	Major facilitator Superfamily
FDQ49_RS02710	COG1024	Enoyl-CoA hydratase
FDQ49_RS02725	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS02730	COG2814	Major facilitator Superfamily
FDQ49_RS02735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDQ49_RS02740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDQ49_RS02755	COG3842	ATPase activity
FDQ49_RS02760	COG1840	ABC-type Fe3 transport system, periplasmic component
FDQ49_RS02770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDQ49_RS02775	COG1414	Transcriptional regulator
FDQ49_RS02785	COG0583	DNA-binding transcription factor activity
FDQ49_RS02800	COG1073	alpha beta
FDQ49_RS02805	COG1073	alpha beta
FDQ49_RS02815	COG1309	transcriptional regulator
FDQ49_RS02835	COG2050	protein possibly involved in aromatic compounds catabolism
FDQ49_RS02845	COG3327	negative regulation of DNA-templated transcription, initiation
FDQ49_RS02850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FDQ49_RS02855	COG0183	Belongs to the thiolase family
FDQ49_RS02860	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDQ49_RS02865	COG1024	Enoyl-CoA hydratase
FDQ49_RS02870	COG1024	Enoyl-CoA hydratase
FDQ49_RS02875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDQ49_RS02880	COG2151	metal-sulfur cluster biosynthetic enzyme
FDQ49_RS02885	COG3396	Phenylacetate-CoA oxygenase
FDQ49_RS02890	COG3460	Phenylacetate-CoA oxygenase
FDQ49_RS02895	COG3396	Phenylacetate-CoA oxygenase
FDQ49_RS02900	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS02900	COG2030	dehydratase
FDQ49_RS02905	COG1760	l-serine dehydratase
FDQ49_RS02910	COG0531	amino acid
FDQ49_RS02915	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS02960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDQ49_RS02975	COG0789	Transcriptional regulator
FDQ49_RS02985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDQ49_RS03000	COG2807	transmembrane transport
FDQ49_RS03005	COG0590	tRNA wobble adenosine to inosine editing
FDQ49_RS03050	COG2885	chlorophyll binding
FDQ49_RS03110	COG0477	Major facilitator Superfamily
FDQ49_RS03125	COG1116	anion transmembrane transporter activity
FDQ49_RS03140	COG0864	Transcriptional regulator
FDQ49_RS03155	COG1733	regulation of RNA biosynthetic process
FDQ49_RS03160	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDQ49_RS03165	COG0439	Biotin carboxylase
FDQ49_RS03180	COG1063	alcohol dehydrogenase
FDQ49_RS03215	COG0038	chloride channel
FDQ49_RS03220	COG4770	biotin carboxylase activity
FDQ49_RS03240	COG1914	H( )-stimulated, divalent metal cation uptake system
FDQ49_RS03245	COG0583	DNA-binding transcription factor activity
FDQ49_RS03255	COG1595	DNA-templated transcription, initiation
FDQ49_RS03265	COG3220	belongs to the UPF0276 family
FDQ49_RS03280	COG0300	oxidoreductase activity
FDQ49_RS03295	COG2076	Multidrug Resistance protein
FDQ49_RS03310	COG3713	MltA-interacting MipA family protein
FDQ49_RS03315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDQ49_RS03435	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDQ49_RS03450	COG0789	Transcriptional regulator
FDQ49_RS03455	COG1278	Cold shock
FDQ49_RS03465	COG0626	cystathionine gamma-synthase activity
FDQ49_RS03475	COG1522	sequence-specific DNA binding
FDQ49_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS03495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDQ49_RS03500	COG4774	siderophore transport
FDQ49_RS03525	COG2814	Major facilitator Superfamily
FDQ49_RS03540	COG1522	sequence-specific DNA binding
FDQ49_RS03575	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS03585	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS03590	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS03610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDQ49_RS03620	COG4122	O-methyltransferase activity
FDQ49_RS03650	COG1538	Outer membrane efflux protein
FDQ49_RS03655	COG1137	ATPase activity
FDQ49_RS03660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDQ49_RS03670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDQ49_RS03675	COG0517	IMP dehydrogenase activity
FDQ49_RS03675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDQ49_RS03755	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS03785	COG1570	exodeoxyribonuclease VII activity
FDQ49_RS03870	COG2871	sodium ion transport
FDQ49_RS03880	COG0583	DNA-binding transcription factor activity
FDQ49_RS03885	COG4638	Rieske (2fe-2S)
FDQ49_RS03890	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDQ49_RS03895	COG0543	2 iron, 2 sulfur cluster binding
FDQ49_RS03895	COG0633	Ferredoxin
FDQ49_RS03900	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS03905	COG3135	benzoate transporter
FDQ49_RS03910	COG2814	Major facilitator Superfamily
FDQ49_RS03925	COG1643	Atp-dependent helicase
FDQ49_RS03930	COG0450	alkyl hydroperoxide reductase
FDQ49_RS03950	COG3634	alkyl hydroperoxide reductase activity
FDQ49_RS03970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDQ49_RS03980	COG0625	glutathione transferase activity
FDQ49_RS03990	COG2885	chlorophyll binding
FDQ49_RS04025	COG0542	response to heat
FDQ49_RS04040	COG1765	OsmC-like protein
FDQ49_RS04050	COG0667	Aldo Keto reductase
FDQ49_RS04065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDQ49_RS04075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDQ49_RS04085	COG0527	aspartate kinase activity
FDQ49_RS04095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDQ49_RS04105	COG3038	cytochrome b561
FDQ49_RS04110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDQ49_RS04115	COG2252	PERMEase
FDQ49_RS04125	COG2072	flavoprotein involved in K transport
FDQ49_RS04140	COG1741	Belongs to the pirin family
FDQ49_RS04145	COG1309	transcriptional regulator
FDQ49_RS04160	COG2072	flavoprotein involved in K transport
FDQ49_RS04165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDQ49_RS04195	COG1944	ATP diphosphatase activity
FDQ49_RS04215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDQ49_RS04230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDQ49_RS04245	COG2814	Major facilitator Superfamily
FDQ49_RS04250	COG1024	Enoyl-CoA hydratase
FDQ49_RS04255	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS04265	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS04285	COG0697	spore germination
FDQ49_RS04305	COG1113	amino acid transport
FDQ49_RS04325	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS04345	COG0531	amino acid
FDQ49_RS04355	COG1113	amino acid transport
FDQ49_RS04420	COG1902	pentaerythritol trinitrate reductase activity
FDQ49_RS04420	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDQ49_RS04435	COG3706	GGDEF domain
FDQ49_RS04435	COG4251	negative regulation of phosphorylation
FDQ49_RS04435	COG2203	Gaf domain
FDQ49_RS04435	COG5001	Diguanylate cyclase
FDQ49_RS04445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDQ49_RS04470	COG4172	Belongs to the ABC transporter superfamily
FDQ49_RS04475	COG4239	(ABC) transporter, permease
FDQ49_RS04480	COG4174	ABC transporter (Permease)
FDQ49_RS04490	COG0741	lytic transglycosylase activity
FDQ49_RS04490	COG0741	lytic transglycosylase activity
FDQ49_RS04490	COG1388	LysM domain
FDQ49_RS04490	COG1388	LysM domain
FDQ49_RS04530	COG0583	DNA-binding transcription factor activity
FDQ49_RS04535	COG1279	arginine transmembrane transporter activity
FDQ49_RS04555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDQ49_RS04560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDQ49_RS04565	COG0006	proline dipeptidase activity
FDQ49_RS04600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDQ49_RS04635	COG3384	dioxygenase
FDQ49_RS04645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDQ49_RS04650	COG2878	Part of a membrane complex involved in electron transport
FDQ49_RS04655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDQ49_RS04680	COG0768	penicillin binding
FDQ49_RS04685	COG0742	ribosomal rna small subunit methyltransferase
FDQ49_RS04705	COG0830	nickel cation binding
FDQ49_RS04715	COG0804	urea catabolic process
FDQ49_RS04755	COG1253	flavin adenine dinucleotide binding
FDQ49_RS04760	COG2851	Citrate transporter
FDQ49_RS04810	COG1773	rubredoxin
FDQ49_RS04815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDQ49_RS04825	COG0583	DNA-binding transcription factor activity
FDQ49_RS04850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDQ49_RS04855	COG4181	ATPase activity
FDQ49_RS04900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDQ49_RS04920	COG0306	phosphate transporter
FDQ49_RS04945	COG2223	nitrite transmembrane transporter activity
FDQ49_RS04950	COG0662	Cupin 2, conserved barrel domain protein
FDQ49_RS04950	COG2207	Transcriptional regulator
FDQ49_RS04955	COG2066	Belongs to the glutaminase family
FDQ49_RS04960	COG0242	peptide deformylase activity
FDQ49_RS04965	COG0477	Major facilitator Superfamily
FDQ49_RS04975	COG0028	Belongs to the TPP enzyme family
FDQ49_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS04995	COG2267	carboxylic ester hydrolase activity
FDQ49_RS05005	COG2271	Major facilitator Superfamily
FDQ49_RS05010	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDQ49_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS05040	COG1414	Transcriptional regulator
FDQ49_RS05065	COG1024	Enoyl-CoA hydratase
FDQ49_RS05075	COG1215	transferase activity, transferring glycosyl groups
FDQ49_RS05080	COG0726	polysaccharide deacetylase
FDQ49_RS05080	COG1649	PFAM Uncharacterised BCR, COG1649
FDQ49_RS05090	COG4681	YaeQ
FDQ49_RS05100	COG0523	cobalamin synthesis protein
FDQ49_RS05110	COG1607	acyl-coa hydrolase
FDQ49_RS05120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDQ49_RS05125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDQ49_RS05130	COG1309	transcriptional regulator
FDQ49_RS05155	COG2040	homocysteine
FDQ49_RS05160	COG0531	amino acid
FDQ49_RS05180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDQ49_RS05185	COG0477	Major facilitator Superfamily
FDQ49_RS05195	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FDQ49_RS05255	COG5000	phosphorelay sensor kinase activity
FDQ49_RS05265	COG0405	Gamma-glutamyltransferase
FDQ49_RS05270	COG2814	Major facilitator Superfamily
FDQ49_RS05280	COG2050	protein possibly involved in aromatic compounds catabolism
FDQ49_RS05295	COG1090	epimerase
FDQ49_RS05315	COG0420	3'-5' exonuclease activity
FDQ49_RS05325	COG1968	undecaprenyl-diphosphatase activity
FDQ49_RS05345	COG0735	belongs to the Fur family
FDQ49_RS05350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDQ49_RS05375	COG0121	glutamine amidotransferase
FDQ49_RS05390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDQ49_RS05400	COG0210	DNA helicase
FDQ49_RS05405	COG2885	chlorophyll binding
FDQ49_RS05410	COG0204	Acyl-transferase
FDQ49_RS05425	COG2894	cell division
FDQ49_RS05440	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS05445	COG1674	ftsk spoiiie
FDQ49_RS05450	COG0492	ferredoxin-NADP+ reductase activity
FDQ49_RS05455	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDQ49_RS05465	COG0456	acetyltransferase
FDQ49_RS05495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FDQ49_RS05510	COG1981	membrane
FDQ49_RS05525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDQ49_RS05525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDQ49_RS05545	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS05550	COG4638	Rieske (2fe-2S)
FDQ49_RS05555	COG0657	acetylesterase activity
FDQ49_RS05565	COG0473	3-isopropylmalate dehydrogenase activity
FDQ49_RS05570	COG0583	DNA-binding transcription factor activity
FDQ49_RS05590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDQ49_RS05625	COG0358	DNA primase activity
FDQ49_RS05640	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDQ49_RS05670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDQ49_RS05700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDQ49_RS05710	COG0352	thiamine-phosphate diphosphorylase activity
FDQ49_RS05710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDQ49_RS05710	COG0351	phosphomethylpyrimidine kinase
FDQ49_RS05715	COG1652	LysM domain
FDQ49_RS05740	COG1399	metal-binding, possibly nucleic acid-binding protein
FDQ49_RS05745	COG3101	peptidyl-lysine hydroxylation
FDQ49_RS05750	COG0009	L-threonylcarbamoyladenylate synthase
FDQ49_RS05755	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDQ49_RS05760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDQ49_RS05775	COG4106	trans-aconitate 2-methyltransferase activity
FDQ49_RS05790	COG0596	Alpha beta hydrolase
FDQ49_RS05790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDQ49_RS05790	COG2226	methyltransferase
FDQ49_RS05795	COG1877	trehalose-phosphatase activity
FDQ49_RS05800	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FDQ49_RS05805	COG2223	nitrite transmembrane transporter activity
FDQ49_RS05825	COG1196	nuclear chromosome segregation
FDQ49_RS05835	COG0730	response to heat
FDQ49_RS05850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDQ49_RS05915	COG0489	protein tyrosine kinase activity
FDQ49_RS05930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDQ49_RS05930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDQ49_RS05965	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FDQ49_RS05970	COG2081	HI0933 family
FDQ49_RS05980	COG0668	transmembrane transport
FDQ49_RS06000	COG0583	DNA-binding transcription factor activity
FDQ49_RS06025	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FDQ49_RS06030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDQ49_RS06060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDQ49_RS06085	COG3706	GGDEF domain
FDQ49_RS06100	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS06120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDQ49_RS06125	COG0384	phenazine biosynthesis protein PhzF
FDQ49_RS06160	COG1309	transcriptional regulator
FDQ49_RS06170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDQ49_RS06185	COG0583	DNA-binding transcription factor activity
FDQ49_RS06215	COG0583	DNA-binding transcription factor activity
FDQ49_RS06235	COG0583	DNA-binding transcription factor activity
FDQ49_RS06240	COG1053	succinate dehydrogenase
FDQ49_RS06255	COG1309	transcriptional regulator
FDQ49_RS06260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDQ49_RS06265	COG2814	Major facilitator Superfamily
FDQ49_RS06270	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS06275	COG0583	DNA-binding transcription factor activity
FDQ49_RS06280	COG1063	alcohol dehydrogenase
FDQ49_RS06310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDQ49_RS06315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDQ49_RS06320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDQ49_RS06340	COG2132	Multicopper oxidase
FDQ49_RS06350	COG0561	phosphatase activity
FDQ49_RS06355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDQ49_RS06380	COG1214	PFAM Peptidase M22, glycoprotease
FDQ49_RS06430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDQ49_RS06440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDQ49_RS06445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDQ49_RS06450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDQ49_RS06510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDQ49_RS06520	COG1846	Transcriptional regulator
FDQ49_RS06525	COG1764	response to oxidative stress
FDQ49_RS06550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDQ49_RS06550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDQ49_RS06565	COG0037	tRNA processing
FDQ49_RS06575	COG0248	Ppx GppA phosphatase
FDQ49_RS06605	COG0072	phenylalanine-tRNA ligase activity
FDQ49_RS06635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FDQ49_RS06645	COG1238	metal cluster binding
FDQ49_RS06650	COG0625	glutathione transferase activity
FDQ49_RS06665	COG0318	PFAM AMP-dependent synthetase and ligase
FDQ49_RS06670	COG3028	Belongs to the UPF0307 family
FDQ49_RS06675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDQ49_RS06695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDQ49_RS06700	COG0617	tRNA 3'-terminal CCA addition
FDQ49_RS06705	COG1555	photosystem II stabilization
FDQ49_RS06710	COG3956	TIGRFAM MazG family protein
FDQ49_RS06720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDQ49_RS06740	COG0784	Response regulator, receiver
FDQ49_RS06740	COG2205	protein histidine kinase activity
FDQ49_RS06740	COG5002	protein histidine kinase activity
FDQ49_RS06745	COG1024	Enoyl-CoA hydratase
FDQ49_RS06750	COG2084	Dehydrogenase
FDQ49_RS06755	COG3622	Belongs to the hyi family
FDQ49_RS06785	COG0697	spore germination
FDQ49_RS06795	COG2814	Major facilitator Superfamily
FDQ49_RS06800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDQ49_RS06820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDQ49_RS06830	COG0084	hydrolase, TatD family'
FDQ49_RS06845	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDQ49_RS06880	COG0440	acetolactate synthase activity
FDQ49_RS06885	COG0028	Belongs to the TPP enzyme family
FDQ49_RS06910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS06915	COG0577	efflux transmembrane transporter activity
FDQ49_RS06915	COG1136	(ABC) transporter
FDQ49_RS06920	COG1538	Outer membrane efflux protein
FDQ49_RS06935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDQ49_RS06940	COG1162	GTPase activity
FDQ49_RS06950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDQ49_RS06970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDQ49_RS06990	COG1426	Protein conserved in bacteria
FDQ49_RS07025	COG0793	Belongs to the peptidase S41A family
FDQ49_RS07050	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS07055	COG3265	gluconokinase activity
FDQ49_RS07065	COG0800	Aldolase
FDQ49_RS07075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDQ49_RS07080	COG0280	phosphate acetyltransferase
FDQ49_RS07080	COG0857	belongs to the CobB CobQ family
FDQ49_RS07085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FDQ49_RS07085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FDQ49_RS07105	COG0740	serine-type endopeptidase activity
FDQ49_RS07115	COG4774	siderophore transport
FDQ49_RS07125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDQ49_RS07135	COG2813	Specifically methylates the guanine in position
FDQ49_RS07135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDQ49_RS07240	COG0788	formyltetrahydrofolate deformylase activity
FDQ49_RS07265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDQ49_RS07265	COG4651	solute:proton antiporter activity
FDQ49_RS07285	COG0724	RNA recognition motif
FDQ49_RS07290	COG0210	DNA helicase
FDQ49_RS07315	COG1733	regulation of RNA biosynthetic process
FDQ49_RS07325	COG2900	Belongs to the SlyX family
FDQ49_RS07330	COG0488	(ABC) transporter
FDQ49_RS07340	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS07345	COG1560	Kdo2-lipid A biosynthetic process
FDQ49_RS07355	COG1301	dicarboxylic acid transport
FDQ49_RS07410	COG0473	3-isopropylmalate dehydrogenase activity
FDQ49_RS07435	COG0583	DNA-binding transcription factor activity
FDQ49_RS07480	COG0583	DNA-binding transcription factor activity
FDQ49_RS07490	COG0625	glutathione transferase activity
FDQ49_RS07495	COG2378	regulation of single-species biofilm formation
FDQ49_RS07505	COG0564	pseudouridine synthase activity
FDQ49_RS07515	COG1530	ribonuclease E activity
FDQ49_RS07520	COG0318	PFAM AMP-dependent synthetase and ligase
FDQ49_RS07535	COG0583	DNA-binding transcription factor activity
FDQ49_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS07545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDQ49_RS07555	COG0534	Mate efflux family protein
FDQ49_RS07570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDQ49_RS07595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDQ49_RS07595	COG0493	'glutamate synthase
FDQ49_RS07605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDQ49_RS07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDQ49_RS07625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDQ49_RS07635	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FDQ49_RS07635	COG0644	oxidoreductase
FDQ49_RS07650	COG4535	Mg2 and Co2 transporter CorC
FDQ49_RS07660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDQ49_RS07685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDQ49_RS07690	COG0475	glutathione-regulated potassium exporter activity
FDQ49_RS07690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDQ49_RS07695	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FDQ49_RS07705	COG0484	heat shock protein binding
FDQ49_RS07710	COG0789	Transcriptional regulator
FDQ49_RS07715	COG0598	Magnesium transport protein CorA
FDQ49_RS07720	COG1185	polyribonucleotide nucleotidyltransferase activity
FDQ49_RS07730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDQ49_RS07735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDQ49_RS07740	COG1074	ATP-dependent DNA helicase activity
FDQ49_RS07745	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDQ49_RS07770	COG2226	methyltransferase
FDQ49_RS07780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDQ49_RS07795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDQ49_RS07810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDQ49_RS07810	COG2111	Na H antiporter
FDQ49_RS07815	COG1006	Multisubunit Na H antiporter MnhC subunit
FDQ49_RS07820	COG0651	ATP synthesis coupled electron transport
FDQ49_RS07825	COG1863	multisubunit Na H antiporter MnhE subunit
FDQ49_RS07830	COG2212	antiporter activity
FDQ49_RS07835	COG1320	monovalent cation:proton antiporter activity
FDQ49_RS07840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FDQ49_RS07850	COG0195	Participates in both transcription termination and antitermination
FDQ49_RS07900	COG0237	dephospho-CoA kinase activity
FDQ49_RS07910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDQ49_RS07925	COG0497	DNA recombination
FDQ49_RS07935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDQ49_RS07950	COG1289	transmembrane transporter activity
FDQ49_RS07965	COG2169	Transcriptional regulator
FDQ49_RS07965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDQ49_RS07970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDQ49_RS08020	COG0326	Molecular chaperone. Has ATPase activity
FDQ49_RS08025	COG3545	Serine hydrolase
FDQ49_RS08040	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FDQ49_RS08055	COG0326	Molecular chaperone. Has ATPase activity
FDQ49_RS08070	COG2056	Na+-H+ antiporter family
FDQ49_RS08075	COG0596	Alpha beta hydrolase
FDQ49_RS08175	COG0546	phosphoglycolate phosphatase activity
FDQ49_RS08180	COG1716	ATPase activity
FDQ49_RS08225	COG0181	hydroxymethylbilane synthase activity
FDQ49_RS08235	COG3275	phosphorelay sensor kinase activity
FDQ49_RS08255	COG1538	Outer membrane efflux protein
FDQ49_RS08265	COG0697	spore germination
FDQ49_RS08285	COG0494	nUDIX hydrolase
FDQ49_RS08290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDQ49_RS08295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDQ49_RS08300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDQ49_RS08305	COG0772	Belongs to the SEDS family
FDQ49_RS08330	COG4974	Belongs to the 'phage' integrase family
FDQ49_RS08335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDQ49_RS08345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDQ49_RS08355	COG2197	response regulator
FDQ49_RS08370	COG0793	Belongs to the peptidase S41A family
FDQ49_RS08375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDQ49_RS08380	COG0795	lipopolysaccharide-transporting ATPase activity
FDQ49_RS08420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDQ49_RS08420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDQ49_RS08430	COG0004	ammonium transporteR
FDQ49_RS08435	COG0347	Belongs to the P(II) protein family
FDQ49_RS08445	COG0606	chelatase, subunit chli
FDQ49_RS08450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDQ49_RS08455	COG0235	Class ii aldolase
FDQ49_RS08460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDQ49_RS08475	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDQ49_RS08490	COG0318	PFAM AMP-dependent synthetase and ligase
FDQ49_RS08500	COG0477	Major facilitator Superfamily
FDQ49_RS08505	COG2860	membrane
FDQ49_RS08515	COG1253	flavin adenine dinucleotide binding
FDQ49_RS08525	COG2814	Major facilitator Superfamily
FDQ49_RS08535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDQ49_RS08570	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDQ49_RS08585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDQ49_RS08620	COG1309	transcriptional regulator
FDQ49_RS08655	COG0758	DNA mediated transformation
FDQ49_RS08665	COG0697	spore germination
FDQ49_RS08670	COG1309	transcriptional regulator
FDQ49_RS08685	COG0386	Belongs to the glutathione peroxidase family
FDQ49_RS08695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FDQ49_RS08750	COG1121	(ABC) transporter
FDQ49_RS08755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDQ49_RS08760	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS08765	COG2837	iron assimilation
FDQ49_RS08770	COG0281	malic enzyme
FDQ49_RS08810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDQ49_RS08815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDQ49_RS08815	COG0519	Catalyzes the synthesis of GMP from XMP
FDQ49_RS08820	COG4399	Belongs to the UPF0754 family
FDQ49_RS08825	COG2259	Doxx family
FDQ49_RS08830	COG0586	Pfam SNARE associated Golgi protein
FDQ49_RS08845	COG1192	Involved in chromosome partitioning
FDQ49_RS08855	COG0271	Belongs to the BolA IbaG family
FDQ49_RS08900	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS08905	COG0318	PFAM AMP-dependent synthetase and ligase
FDQ49_RS08910	COG2197	response regulator
FDQ49_RS08920	COG3916	Acyl-homoserine-lactone synthase
FDQ49_RS08925	COG0477	Major facilitator Superfamily
FDQ49_RS08930	COG1024	Enoyl-CoA hydratase
FDQ49_RS08935	COG1024	Enoyl-CoA hydratase
FDQ49_RS08940	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS08945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDQ49_RS08965	COG1113	amino acid transport
FDQ49_RS08970	COG1113	amino acid transport
FDQ49_RS08975	COG0251	oxidation-reduction process
FDQ49_RS09015	COG0564	pseudouridine synthase activity
FDQ49_RS09080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDQ49_RS09095	COG1802	Transcriptional regulator
FDQ49_RS09105	COG1448	Aminotransferase
FDQ49_RS09110	COG0277	FAD linked oxidase domain protein
FDQ49_RS09120	COG2186	Transcriptional regulator
FDQ49_RS09130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDQ49_RS09150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDQ49_RS09155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDQ49_RS09170	COG0110	maltose O-acetyltransferase activity
FDQ49_RS09175	COG1216	Glycosyl transferase, family 2
FDQ49_RS09175	COG0463	Glycosyl transferase, family 2
FDQ49_RS09200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FDQ49_RS09205	COG1091	dTDP-4-dehydrorhamnose reductase activity
FDQ49_RS09215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDQ49_RS09220	COG1596	polysaccharide export
FDQ49_RS09245	COG0728	peptidoglycan biosynthetic process
FDQ49_RS09250	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDQ49_RS09305	COG0546	phosphoglycolate phosphatase activity
FDQ49_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS09325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FDQ49_RS09325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FDQ49_RS09330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDQ49_RS09335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDQ49_RS09340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDQ49_RS09345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS09350	COG1116	anion transmembrane transporter activity
FDQ49_RS09355	COG1309	transcriptional regulator
FDQ49_RS09360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDQ49_RS09370	COG0196	riboflavin kinase activity
FDQ49_RS09375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDQ49_RS09385	COG1047	Peptidyl-prolyl cis-trans
FDQ49_RS09425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDQ49_RS09430	COG0657	acetylesterase activity
FDQ49_RS09480	COG2951	lytic endotransglycosylase activity
FDQ49_RS09485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDQ49_RS09505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDQ49_RS09515	COG0671	phosphoesterase, PA-phosphatase related
FDQ49_RS09520	COG0861	Integral membrane protein TerC family
FDQ49_RS09530	COG0754	glutathionylspermidine amidase activity
FDQ49_RS09540	COG0402	S-adenosylhomocysteine deaminase activity
FDQ49_RS09555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDQ49_RS09560	COG1230	cation diffusion facilitator family transporter
FDQ49_RS09575	COG0706	membrane insertase activity
FDQ49_RS09600	COG0592	DNA-directed DNA polymerase activity
FDQ49_RS09610	COG0187	DNA topoisomerase II activity
FDQ49_RS09620	COG0586	Pfam SNARE associated Golgi protein
FDQ49_RS09625	COG0488	(ABC) transporter
FDQ49_RS09650	COG0596	Alpha beta hydrolase
FDQ49_RS09655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDQ49_RS09660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDQ49_RS09700	COG0733	neurotransmitter:sodium symporter activity
FDQ49_RS09740	COG2233	PERMEase
FDQ49_RS09755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS09790	COG2814	Major facilitator Superfamily
FDQ49_RS09795	COG0656	L-ascorbic acid biosynthetic process
FDQ49_RS09800	COG0583	DNA-binding transcription factor activity
FDQ49_RS09815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDQ49_RS09820	COG1064	alcohol dehydrogenase
FDQ49_RS09825	COG2818	Glycosylase
FDQ49_RS09840	COG1194	a g-specific adenine glycosylase
FDQ49_RS09855	COG5487	UPF0391 membrane protein
FDQ49_RS09860	COG2983	Belongs to the UPF0260 family
FDQ49_RS09865	COG2133	pyrroloquinoline quinone binding
FDQ49_RS09870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDQ49_RS09875	COG2116	formate transmembrane transporter activity
FDQ49_RS09895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDQ49_RS09900	COG1335	isochorismatase
FDQ49_RS09905	COG0385	Bile acid
FDQ49_RS09910	COG0534	Mate efflux family protein
FDQ49_RS09915	COG1683	Conserved Protein
FDQ49_RS09935	COG0625	glutathione transferase activity
FDQ49_RS09945	COG1113	amino acid transport
FDQ49_RS09955	COG0523	cobalamin synthesis protein
FDQ49_RS09965	COG2188	Transcriptional regulator
FDQ49_RS09995	COG0010	Belongs to the arginase family
FDQ49_RS10005	COG0546	phosphoglycolate phosphatase activity
FDQ49_RS10010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDQ49_RS10015	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS10030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDQ49_RS10040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDQ49_RS10045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDQ49_RS10140	COG0534	Mate efflux family protein
FDQ49_RS10145	COG0436	Aminotransferase
FDQ49_RS10150	COG2733	membrane
FDQ49_RS10165	COG2918	glutathione biosynthetic process
FDQ49_RS10180	COG1388	LysM domain
FDQ49_RS10180	COG0791	NLP P60 protein
FDQ49_RS10225	COG3150	esterase
FDQ49_RS10235	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FDQ49_RS10245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDQ49_RS10255	COG2233	PERMEase
FDQ49_RS10260	COG2351	hydroxyisourate hydrolase activity
FDQ49_RS10295	COG3706	GGDEF domain
FDQ49_RS10310	COG1393	Belongs to the ArsC family
FDQ49_RS10315	COG0708	Exodeoxyribonuclease III
FDQ49_RS10335	COG0189	ligase activity
FDQ49_RS10360	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDQ49_RS10370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDQ49_RS10385	COG4942	peptidase
FDQ49_RS10395	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDQ49_RS10405	COG2119	membrane
FDQ49_RS10410	COG0426	domain, Protein
FDQ49_RS10410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDQ49_RS10435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDQ49_RS10455	COG1902	pentaerythritol trinitrate reductase activity
FDQ49_RS10460	COG1519	Transferase
FDQ49_RS10465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDQ49_RS10470	COG0668	transmembrane transport
FDQ49_RS10480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDQ49_RS10485	COG1335	isochorismatase
FDQ49_RS10490	COG1522	sequence-specific DNA binding
FDQ49_RS10515	COG0784	Response regulator, receiver
FDQ49_RS10515	COG2198	Histidine kinase
FDQ49_RS10515	COG2205	protein histidine kinase activity
FDQ49_RS10520	COG3162	membrane
FDQ49_RS10525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDQ49_RS10535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDQ49_RS10555	COG1309	transcriptional regulator
FDQ49_RS10575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDQ49_RS10575	COG0352	thiamine-phosphate diphosphorylase activity
FDQ49_RS10575	COG0351	phosphomethylpyrimidine kinase
FDQ49_RS10585	COG2814	Major facilitator Superfamily
FDQ49_RS10600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDQ49_RS10610	COG1113	amino acid transport
FDQ49_RS10620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDQ49_RS10625	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS10635	COG1335	isochorismatase
FDQ49_RS10670	COG2814	Major facilitator Superfamily
FDQ49_RS10675	COG0583	DNA-binding transcription factor activity
FDQ49_RS10695	COG0667	Aldo Keto reductase
FDQ49_RS10720	COG1733	regulation of RNA biosynthetic process
FDQ49_RS10740	COG1733	regulation of RNA biosynthetic process
FDQ49_RS10745	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDQ49_RS10815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDQ49_RS10855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDQ49_RS10885	COG0427	acetyl-CoA hydrolase
FDQ49_RS10910	COG0659	secondary active sulfate transmembrane transporter activity
FDQ49_RS10915	COG4221	oxidoreductase activity
FDQ49_RS10920	COG2873	o-acetylhomoserine
FDQ49_RS10925	COG0028	Belongs to the TPP enzyme family
FDQ49_RS10930	COG0488	(ABC) transporter
FDQ49_RS10995	COG0833	amino acid
FDQ49_RS11040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDQ49_RS11045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDQ49_RS11060	COG2226	methyltransferase
FDQ49_RS11110	COG0069	glutamate synthase activity
FDQ49_RS11110	COG0070	glutamate synthase
FDQ49_RS11110	COG0067	glutamate synthase
FDQ49_RS11115	COG0493	'glutamate synthase
FDQ49_RS11125	COG1704	LemA family
FDQ49_RS11130	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FDQ49_RS11150	COG3307	-O-antigen
FDQ49_RS11170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDQ49_RS11185	COG0194	GDP metabolic process
FDQ49_RS11235	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDQ49_RS11255	COG5380	lipid catabolic process
FDQ49_RS11260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDQ49_RS11275	COG5006	permease, DMT superfamily
FDQ49_RS11280	COG5006	permease, DMT superfamily
FDQ49_RS11285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDQ49_RS11290	COG0277	FAD linked oxidase domain protein
FDQ49_RS11305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDQ49_RS11310	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDQ49_RS11325	COG1289	transmembrane transporter activity
FDQ49_RS11335	COG0628	permease
FDQ49_RS11340	COG1192	Involved in chromosome partitioning
FDQ49_RS11370	COG0833	amino acid
FDQ49_RS11375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDQ49_RS11390	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS11430	COG0583	DNA-binding transcription factor activity
FDQ49_RS11475	COG0517	IMP dehydrogenase activity
FDQ49_RS11480	COG1983	PspC domain protein
FDQ49_RS11490	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS11505	COG0408	coproporphyrinogen oxidase activity
FDQ49_RS11530	COG1127	ABC transporter
FDQ49_RS11535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDQ49_RS11545	COG2854	intermembrane phospholipid transfer
FDQ49_RS11555	COG0598	Magnesium transport protein CorA
FDQ49_RS11565	COG0494	nUDIX hydrolase
FDQ49_RS11570	COG1040	competence protein
FDQ49_RS11575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDQ49_RS11595	COG1946	Acyl-CoA thioesterase
FDQ49_RS11600	COG1301	dicarboxylic acid transport
FDQ49_RS11615	COG1959	2 iron, 2 sulfur cluster binding
FDQ49_RS11620	COG1017	nitric oxide dioxygenase activity
FDQ49_RS11620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDQ49_RS11625	COG0433	COG0433 Predicted ATPase
FDQ49_RS11630	COG0626	cystathionine gamma-synthase activity
FDQ49_RS11645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FDQ49_RS11650	COG0088	Forms part of the polypeptide exit tunnel
FDQ49_RS11785	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS11790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDQ49_RS11820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FDQ49_RS11825	COG0339	signal peptide processing
FDQ49_RS11830	COG0557	exoribonuclease II activity
FDQ49_RS11875	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDQ49_RS11880	COG2207	Transcriptional regulator
FDQ49_RS11890	COG1295	ribonuclease BN
FDQ49_RS11925	COG1702	phosphate starvation-inducible protein PhoH
FDQ49_RS11935	COG1196	nuclear chromosome segregation
FDQ49_RS11935	COG0741	lytic transglycosylase activity
FDQ49_RS11935	COG0739	heme binding
FDQ49_RS11965	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDQ49_RS11970	COG1183	phosphatidylcholine synthase activity
FDQ49_RS12020	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS12025	COG1309	transcriptional regulator
FDQ49_RS12040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDQ49_RS12045	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS12085	COG2969	positive regulation of protein catabolic process
FDQ49_RS12095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDQ49_RS12100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FDQ49_RS12105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDQ49_RS12110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDQ49_RS12115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDQ49_RS12135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDQ49_RS12145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDQ49_RS12150	COG1408	metallophosphoesterase
FDQ49_RS12160	COG2199	diguanylate cyclase activity
FDQ49_RS12195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDQ49_RS12220	COG1607	acyl-coa hydrolase
FDQ49_RS12255	COG2350	Protein conserved in bacteria
FDQ49_RS12265	COG0613	PHP domain protein
FDQ49_RS12270	COG3781	membrane
FDQ49_RS12280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDQ49_RS12285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDQ49_RS12295	COG1862	Preprotein translocase
FDQ49_RS12335	COG2198	Histidine kinase
FDQ49_RS12335	COG0784	Response regulator, receiver
FDQ49_RS12335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDQ49_RS12335	COG2205	protein histidine kinase activity
FDQ49_RS12340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDQ49_RS12355	COG2194	sulfuric ester hydrolase activity
FDQ49_RS12365	COG0726	polysaccharide deacetylase
FDQ49_RS12370	COG0463	Glycosyl transferase, family 2
FDQ49_RS12375	COG0438	transferase activity, transferring glycosyl groups
FDQ49_RS12445	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS12450	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS12460	COG2205	protein histidine kinase activity
FDQ49_RS12465	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS12470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDQ49_RS12490	COG2096	Adenosyltransferase
FDQ49_RS12495	COG4206	TonB-dependent receptor
FDQ49_RS12545	COG0285	dihydrofolate synthase activity
FDQ49_RS12565	COG0450	alkyl hydroperoxide reductase
FDQ49_RS12580	COG0477	Major facilitator Superfamily
FDQ49_RS12585	COG1272	protein, Hemolysin III
FDQ49_RS12595	COG2153	protein acetylation
FDQ49_RS12615	COG0183	Belongs to the thiolase family
FDQ49_RS12620	COG2207	Transcriptional regulator
FDQ49_RS12640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDQ49_RS12660	COG0183	Belongs to the thiolase family
FDQ49_RS12670	COG2885	chlorophyll binding
FDQ49_RS12670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDQ49_RS12675	COG1690	Belongs to the RtcB family
FDQ49_RS12680	COG0833	amino acid
FDQ49_RS12690	COG2233	PERMEase
FDQ49_RS12695	COG1217	gtp-binding protein TYPA
FDQ49_RS12720	COG2094	Belongs to the DNA glycosylase MPG family
FDQ49_RS12725	COG4772	TonB-dependent receptor
FDQ49_RS12730	COG1902	pentaerythritol trinitrate reductase activity
FDQ49_RS12735	COG0679	Auxin Efflux Carrier
FDQ49_RS12745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDQ49_RS12750	COG0354	folic acid binding
FDQ49_RS12760	COG3189	MarR family transcriptional regulator
FDQ49_RS12765	COG2824	Alkylphosphonate utilization operon protein PhnA
FDQ49_RS12770	COG3422	double-strand break repair
FDQ49_RS12810	COG0840	transmembrane signaling receptor activity
FDQ49_RS12815	COG0643	Histidine kinase
FDQ49_RS12815	COG0784	Response regulator, receiver
FDQ49_RS12815	COG2198	Histidine kinase
FDQ49_RS12845	COG2832	Protein of unknown function (DUF454)
FDQ49_RS12850	COG1376	ErfK ybiS ycfS ynhG family protein
FDQ49_RS12890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDQ49_RS12900	COG1289	transmembrane transporter activity
FDQ49_RS12905	COG2814	Major facilitator Superfamily
FDQ49_RS12930	COG1115	amino acid carrier protein
FDQ49_RS12935	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDQ49_RS12940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDQ49_RS12945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FDQ49_RS12975	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDQ49_RS12985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDQ49_RS12990	COG1077	Cell shape determining protein MreB Mrl
FDQ49_RS12995	COG1792	Involved in formation and maintenance of cell shape
FDQ49_RS13000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDQ49_RS13005	COG0424	maF-like protein
FDQ49_RS13010	COG1530	ribonuclease E activity
FDQ49_RS13020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDQ49_RS13040	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDQ49_RS13065	COG2207	Transcriptional regulator
FDQ49_RS13095	COG3046	protein related to deoxyribodipyrimidine photolyase
FDQ49_RS13100	COG2816	NAD+ diphosphatase activity
FDQ49_RS13105	COG1113	amino acid transport
FDQ49_RS13115	COG0142	geranyltranstransferase activity
FDQ49_RS13120	COG2315	Protein conserved in bacteria
FDQ49_RS13135	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDQ49_RS13155	COG2194	sulfuric ester hydrolase activity
FDQ49_RS13160	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS13165	COG0642	Histidine kinase
FDQ49_RS13175	COG0004	ammonium transporteR
FDQ49_RS13185	COG0583	DNA-binding transcription factor activity
FDQ49_RS13205	COG0525	valine-tRNA ligase activity
FDQ49_RS13215	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS13225	COG0393	Putative heavy-metal-binding
FDQ49_RS13230	COG0393	Putative heavy-metal-binding
FDQ49_RS13235	COG1538	Outer membrane efflux protein
FDQ49_RS13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS13250	COG0671	phosphoesterase, PA-phosphatase related
FDQ49_RS13280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDQ49_RS13295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDQ49_RS13295	COG1648	precorrin-2 dehydrogenase activity
FDQ49_RS13300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDQ49_RS13305	COG1733	regulation of RNA biosynthetic process
FDQ49_RS13315	COG0531	amino acid
FDQ49_RS13330	COG0321	lipoyl(octanoyl) transferase activity
FDQ49_RS13335	COG2921	Belongs to the UPF0250 family
FDQ49_RS13370	COG2009	succinate dehydrogenase
FDQ49_RS13375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDQ49_RS13380	COG1053	succinate dehydrogenase
FDQ49_RS13385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDQ49_RS13410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDQ49_RS13430	COG2354	Protein conserved in bacteria
FDQ49_RS13435	COG2321	neutral zinc metallopeptidase
FDQ49_RS13455	COG2843	Capsule synthesis protein
FDQ49_RS13475	COG0589	response to stress
FDQ49_RS13485	COG0251	oxidation-reduction process
FDQ49_RS13490	COG1309	transcriptional regulator
FDQ49_RS13505	COG0505	Belongs to the CarA family
FDQ49_RS13535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDQ49_RS13540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDQ49_RS13590	COG0477	Major facilitator Superfamily
FDQ49_RS13595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDQ49_RS13610	COG1597	lipid kinase activity
FDQ49_RS13615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDQ49_RS13635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDQ49_RS13640	COG0584	glycerophosphoryl diester phosphodiesterase
FDQ49_RS13660	COG0741	lytic transglycosylase activity
FDQ49_RS13685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDQ49_RS13700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDQ49_RS13730	COG1309	transcriptional regulator
FDQ49_RS13735	COG1902	pentaerythritol trinitrate reductase activity
FDQ49_RS13740	COG0596	Alpha beta hydrolase
FDQ49_RS13740	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDQ49_RS13745	COG0596	Alpha beta hydrolase
FDQ49_RS13755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS13760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDQ49_RS13765	COG0778	Nitroreductase
FDQ49_RS13770	COG0300	oxidoreductase activity
FDQ49_RS13780	COG1929	Belongs to the glycerate kinase type-1 family
FDQ49_RS13785	COG0243	molybdopterin cofactor binding
FDQ49_RS13790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDQ49_RS13795	COG3339	Conserved Protein
FDQ49_RS13805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDQ49_RS13820	COG1113	amino acid transport
FDQ49_RS13825	COG1113	amino acid transport
FDQ49_RS13835	COG0019	diaminopimelate decarboxylase activity
FDQ49_RS13850	COG1280	lysine exporter protein (LysE YggA)
FDQ49_RS13855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDQ49_RS13875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDQ49_RS13885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FDQ49_RS13895	COG0463	Glycosyl transferase, family 2
FDQ49_RS13915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS13945	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDQ49_RS13950	COG1136	(ABC) transporter
FDQ49_RS13965	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDQ49_RS13965	COG0616	signal peptide processing
FDQ49_RS13970	COG0596	Alpha beta hydrolase
FDQ49_RS13975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDQ49_RS13985	COG0628	permease
FDQ49_RS14020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDQ49_RS14040	COG0823	Involved in the tonB-independent uptake of proteins
FDQ49_RS14060	COG0824	Thioesterase
FDQ49_RS14065	COG1473	amidohydrolase
FDQ49_RS14085	COG0047	phosphoribosylformylglycinamidine synthase activity
FDQ49_RS14085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDQ49_RS14090	COG2814	Major facilitator Superfamily
FDQ49_RS14105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDQ49_RS14110	COG1024	Enoyl-CoA hydratase
FDQ49_RS14115	COG1056	cytidyltransferase-related domain
FDQ49_RS14115	COG1051	belongs to the nudix hydrolase family
FDQ49_RS14130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDQ49_RS14145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDQ49_RS14150	COG0602	queuosine metabolic process
FDQ49_RS14160	COG4625	pathogenesis
FDQ49_RS14165	COG0583	DNA-binding transcription factor activity
FDQ49_RS14170	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDQ49_RS14175	COG4208	sulfate ABC transporter
FDQ49_RS14180	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FDQ49_RS14190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FDQ49_RS14195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDQ49_RS14200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDQ49_RS14220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDQ49_RS14235	COG0481	GTPase activity
FDQ49_RS14240	COG0681	Belongs to the peptidase S26 family
FDQ49_RS14255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDQ49_RS14265	COG1381	Involved in DNA repair and RecF pathway recombination
FDQ49_RS14270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDQ49_RS14280	COG4221	oxidoreductase activity
FDQ49_RS14310	COG0436	Aminotransferase
FDQ49_RS14330	COG0556	nucleotide-excision repair
FDQ49_RS14385	COG2070	2-Nitropropane dioxygenase
FDQ49_RS14415	COG1215	transferase activity, transferring glycosyl groups
FDQ49_RS14430	COG0415	Belongs to the DNA photolyase family
FDQ49_RS14440	COG1252	NADH dehydrogenase
FDQ49_RS14445	COG1686	Belongs to the peptidase S11 family
FDQ49_RS14460	COG1187	pseudouridine synthase activity
FDQ49_RS14485	COG0477	Major facilitator Superfamily
FDQ49_RS14490	COG0583	DNA-binding transcription factor activity
FDQ49_RS14495	COG1823	symporter activity
FDQ49_RS14505	COG0612	Peptidase, M16
FDQ49_RS14530	COG0352	thiamine-phosphate diphosphorylase activity
FDQ49_RS14565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDQ49_RS14590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDQ49_RS14595	COG0076	glutamate decarboxylase activity
FDQ49_RS14605	COG1522	sequence-specific DNA binding
FDQ49_RS14610	COG3961	Belongs to the TPP enzyme family
FDQ49_RS14615	COG1113	amino acid transport
FDQ49_RS14620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDQ49_RS14625	COG0573	inorganic phosphate transmembrane transporter activity
FDQ49_RS14635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDQ49_RS14640	COG0616	signal peptide processing
FDQ49_RS14655	COG3647	Membrane
FDQ49_RS14680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDQ49_RS14685	COG1686	Belongs to the peptidase S11 family
FDQ49_RS14710	COG0583	DNA-binding transcription factor activity
FDQ49_RS14715	COG1067	ATP-dependent peptidase activity
FDQ49_RS14740	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDQ49_RS14755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDQ49_RS14760	COG1966	Carbon starvation protein
FDQ49_RS14765	COG2879	small protein
FDQ49_RS14800	COG2814	Major facilitator Superfamily
FDQ49_RS14840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FDQ49_RS14845	COG2423	ornithine cyclodeaminase activity
FDQ49_RS14855	COG2964	Protein conserved in bacteria
FDQ49_RS14860	COG1741	Belongs to the pirin family
FDQ49_RS14880	COG3739	integral membrane protein
FDQ49_RS14900	COG0302	gtp cyclohydrolase
FDQ49_RS14910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FDQ49_RS14920	COG2840	Smr protein MutS2
FDQ49_RS14945	COG0512	Glutamine amidotransferase of anthranilate synthase
FDQ49_RS14960	COG0174	glutamine synthetase
FDQ49_RS14970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDQ49_RS15005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDQ49_RS15010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDQ49_RS15015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDQ49_RS15035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDQ49_RS15040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDQ49_RS15045	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FDQ49_RS15060	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS15065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDQ49_RS15070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDQ49_RS15080	COG2223	nitrite transmembrane transporter activity
FDQ49_RS15090	COG0024	Methionine aminopeptidase
FDQ49_RS15095	COG0052	Belongs to the universal ribosomal protein uS2 family
FDQ49_RS15110	COG2207	Transcriptional regulator
FDQ49_RS15135	COG2951	lytic endotransglycosylase activity
FDQ49_RS15140	COG0772	Belongs to the SEDS family
FDQ49_RS15155	COG0842	Transport permease protein
FDQ49_RS15160	COG1131	(ABC) transporter
FDQ49_RS15200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDQ49_RS15215	COG4215	(ABC) transporter
FDQ49_RS15220	COG4160	amino acid transport
FDQ49_RS15225	COG4598	ABC transporter
FDQ49_RS15235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDQ49_RS15240	COG0826	peptidase U32
FDQ49_RS15245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDQ49_RS15250	COG0384	phenazine biosynthesis protein PhzF
FDQ49_RS15260	COG1720	tRNA m6t6A37 methyltransferase activity
FDQ49_RS15270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDQ49_RS15285	COG0642	Histidine kinase
FDQ49_RS15295	COG0494	nUDIX hydrolase
FDQ49_RS15305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDQ49_RS15310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDQ49_RS15315	COG3139	Protein of unknown function (DUF1315)
FDQ49_RS15320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDQ49_RS15330	COG1301	dicarboxylic acid transport
FDQ49_RS15345	COG2819	hydrolase of the alpha beta superfamily
FDQ49_RS15355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDQ49_RS15365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDQ49_RS15370	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDQ49_RS15375	COG1234	tRNA 3'-trailer cleavage
FDQ49_RS15405	COG2363	Small membrane protein
FDQ49_RS15425	COG0513	Belongs to the DEAD box helicase family
FDQ49_RS15435	COG0778	Nitroreductase
FDQ49_RS15465	COG1286	toxin biosynthetic process
FDQ49_RS15495	COG1610	YqeY-like protein
FDQ49_RS15525	COG0515	serine threonine protein kinase
FDQ49_RS15525	COG2815	serine threonine protein kinase
FDQ49_RS15550	COG2831	hemolysin activation secretion protein
FDQ49_RS15580	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FDQ49_RS15660	COG2226	methyltransferase
FDQ49_RS15670	COG3111	PFAM Bacterial OB fold (BOF) protein
FDQ49_RS15685	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDQ49_RS15690	COG0786	glutamate:sodium symporter activity
FDQ49_RS15695	COG0583	DNA-binding transcription factor activity
FDQ49_RS15705	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS15715	COG0475	glutathione-regulated potassium exporter activity
FDQ49_RS15715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDQ49_RS15770	COG1560	Kdo2-lipid A biosynthetic process
FDQ49_RS15830	COG2169	Transcriptional regulator
FDQ49_RS15830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDQ49_RS15845	COG2985	domain, Protein
FDQ49_RS15860	COG0583	DNA-binding transcription factor activity
FDQ49_RS15870	COG2995	paraquat-inducible protein a
FDQ49_RS15875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDQ49_RS15875	COG3008	intermembrane lipid transfer
FDQ49_RS15885	COG2351	hydroxyisourate hydrolase activity
FDQ49_RS15900	COG5002	protein histidine kinase activity
FDQ49_RS15925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDQ49_RS15935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDQ49_RS15940	COG0642	Histidine kinase
FDQ49_RS15945	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS15970	COG2175	clavaminate synthase activity
FDQ49_RS15975	COG3246	L-lysine catabolic process to acetate
FDQ49_RS15980	COG2814	Major facilitator Superfamily
FDQ49_RS15995	COG2855	membrane
FDQ49_RS16040	COG1301	dicarboxylic acid transport
FDQ49_RS16050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDQ49_RS16055	COG2011	ABC-type metal ion transport system permease component
FDQ49_RS16060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDQ49_RS16065	COG1464	Belongs to the NlpA lipoprotein family
FDQ49_RS16070	COG0151	Belongs to the GarS family
FDQ49_RS16075	COG0138	bifunctional purine biosynthesis protein purh
FDQ49_RS16080	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDQ49_RS16110	COG2308	Evidence 4 Homologs of previously reported genes of
FDQ49_RS16120	COG1305	Transglutaminase-like
FDQ49_RS16130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDQ49_RS16135	COG0305	Participates in initiation and elongation during chromosome replication
FDQ49_RS16160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDQ49_RS16170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDQ49_RS16200	COG1649	PFAM Uncharacterised BCR, COG1649
FDQ49_RS16200	COG0726	polysaccharide deacetylase
FDQ49_RS16205	COG1215	transferase activity, transferring glycosyl groups
FDQ49_RS16210	COG3658	cytochrome
FDQ49_RS16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDQ49_RS16240	COG0583	DNA-binding transcription factor activity
FDQ49_RS16260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDQ49_RS16265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDQ49_RS16280	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS16285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDQ49_RS16290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDQ49_RS16315	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FDQ49_RS16320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FDQ49_RS16325	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FDQ49_RS16330	COG2205	protein histidine kinase activity
FDQ49_RS16335	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS16340	COG0174	glutamine synthetase
FDQ49_RS16360	COG0729	surface antigen
FDQ49_RS16390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDQ49_RS16395	COG2814	Major facilitator Superfamily
FDQ49_RS16405	COG0583	DNA-binding transcription factor activity
FDQ49_RS16420	COG1187	pseudouridine synthase activity
FDQ49_RS16440	COG0802	atpase or kinase
FDQ49_RS16445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDQ49_RS16455	COG1923	regulation of RNA biosynthetic process
FDQ49_RS16460	COG0697	spore germination
FDQ49_RS16475	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDQ49_RS16490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDQ49_RS16490	COG0519	Catalyzes the synthesis of GMP from XMP
FDQ49_RS16495	COG4302	ethanolamine ammonia-lyase activity
FDQ49_RS16500	COG4303	Ethanolamine ammonia lyase large subunit
FDQ49_RS16505	COG0531	amino acid
FDQ49_RS16525	COG1454	alcohol dehydrogenase
FDQ49_RS16530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDQ49_RS16540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FDQ49_RS16560	COG0308	aminopeptidase N
FDQ49_RS16590	COG0625	glutathione transferase activity
FDQ49_RS16605	COG1605	Chorismate mutase
FDQ49_RS16645	COG4264	IucA IucC family
FDQ49_RS16655	COG4264	IucA IucC family
FDQ49_RS16660	COG2423	ornithine cyclodeaminase activity
FDQ49_RS16665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDQ49_RS16670	COG0668	transmembrane transport
FDQ49_RS16715	COG0488	(ABC) transporter
FDQ49_RS16720	COG0589	response to stress
FDQ49_RS16735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FDQ49_RS16745	COG3135	benzoate transporter
FDQ49_RS16750	COG1522	sequence-specific DNA binding
FDQ49_RS16760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDQ49_RS16765	COG0583	DNA-binding transcription factor activity
FDQ49_RS16775	COG0183	Belongs to the thiolase family
FDQ49_RS16785	COG2030	dehydratase
FDQ49_RS16790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDQ49_RS16815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDQ49_RS16825	COG0824	Thioesterase
FDQ49_RS16830	COG1454	alcohol dehydrogenase
FDQ49_RS16840	COG1335	isochorismatase
FDQ49_RS16855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FDQ49_RS16885	COG0069	glutamate synthase activity
FDQ49_RS16920	COG2814	Major facilitator Superfamily
FDQ49_RS16930	COG0439	Biotin carboxylase
FDQ49_RS16935	COG0511	ligase activity, forming carbon-carbon bonds
FDQ49_RS16950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDQ49_RS16950	COG1116	anion transmembrane transporter activity
FDQ49_RS16955	COG0745	RESPONSE REGULATOR receiver
FDQ49_RS16965	COG2146	nitrite reductase [NAD(P)H] activity
FDQ49_RS16965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDQ49_RS16970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDQ49_RS16975	COG0243	molybdopterin cofactor binding
FDQ49_RS17005	COG0243	molybdopterin cofactor binding
FDQ49_RS17010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDQ49_RS17025	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDQ49_RS17025	COG0315	cyclic pyranopterin monophosphate synthase activity
FDQ49_RS17030	COG0303	'Molybdopterin
FDQ49_RS17040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDQ49_RS17045	COG0697	spore germination
FDQ49_RS17065	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDQ49_RS17070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDQ49_RS17130	COG2204	response regulator
FDQ49_RS17135	COG3852	Histidine kinase
FDQ49_RS17160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDQ49_RS17165	COG0575	Belongs to the CDS family
FDQ49_RS17200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDQ49_RS17215	COG2137	regulation of response to DNA damage stimulus
FDQ49_RS17225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDQ49_RS17230	COG1011	Hydrolase
FDQ49_RS17250	COG1522	sequence-specific DNA binding
FDQ49_RS17260	COG1113	amino acid transport
FDQ49_RS17275	COG0659	secondary active sulfate transmembrane transporter activity
FDQ49_RS17280	COG2135	peptidase activity
FDQ49_RS17295	COG5001	Diguanylate cyclase
FDQ49_RS17295	COG3300	MHYT domain
FDQ49_RS17310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDQ49_RS17310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDQ49_RS17310	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDQ49_RS17315	COG1105	Belongs to the carbohydrate kinase PfkB family
FDQ49_RS17320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDQ49_RS17320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDQ49_RS17350	COG0024	Methionine aminopeptidase
FDQ49_RS17355	COG0583	DNA-binding transcription factor activity
FDQ49_RS17365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDQ49_RS17370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDQ49_RS17375	COG0517	IMP dehydrogenase activity
FDQ49_RS17375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDQ49_RS17400	COG0552	protein localization to endoplasmic reticulum
FDQ49_RS17410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDQ49_RS17425	COG4890	Cyd operon protein YbgT
FDQ49_RS17430	COG1294	oxidase, subunit
FDQ49_RS17445	COG1585	Membrane protein implicated in regulation of membrane protease activity
FDQ49_RS17455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDQ49_RS17460	COG4774	siderophore transport
FDQ49_RS17475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDQ49_RS17480	COG0569	domain protein
FDQ49_RS17485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDQ49_RS17515	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDQ49_RS17520	COG0542	response to heat
FDQ49_RS17530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDQ49_RS17545	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDQ49_RS17545	COG1902	pentaerythritol trinitrate reductase activity
FDQ49_RS17590	COG2323	membrane
FDQ49_RS17600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDQ49_RS17610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDQ49_RS17615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDQ49_RS17620	COG0183	Belongs to the thiolase family
FDQ49_RS17625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDQ49_RS17630	COG0596	Alpha beta hydrolase
FDQ49_RS17635	COG2271	Major facilitator Superfamily
FDQ49_RS17640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDQ49_RS17645	COG3485	protocatechuate 3,4-dioxygenase
FDQ49_RS17650	COG3485	protocatechuate 3,4-dioxygenase
FDQ49_RS17655	COG0710	3-dehydroquinate dehydratase activity
FDQ49_RS17660	COG3420	alginic acid biosynthetic process
FDQ49_RS17665	COG3659	wide pore channel activity
FDQ49_RS17670	COG4993	Dehydrogenase
FDQ49_RS17680	COG2391	methyltransferase activity
FDQ49_RS17695	COG1414	Transcriptional regulator
FDQ49_RS17700	COG0583	DNA-binding transcription factor activity
FDQ49_RS17705	COG1960	acyl-CoA dehydrogenase activity
FDQ49_RS17730	COG2814	Major facilitator Superfamily
FDQ49_RS17740	COG0154	amidase activity
FDQ49_RS17760	COG4638	Rieske (2fe-2S)
FDQ49_RS17770	COG1028	Short-chain dehydrogenase reductase Sdr
FDQ49_RS17780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDQ49_RS17790	COG3733	amine oxidase
FDQ49_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
FDQ49_RS17805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDQ49_RS17810	COG0183	Belongs to the thiolase family
FDQ49_RS17815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDQ49_RS17820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDQ49_RS17830	COG4829	muconolactone delta-isomerase
FDQ49_RS17835	COG4948	Mandelate Racemase Muconate Lactonizing
FDQ49_RS17840	COG0583	DNA-binding transcription factor activity
FDQ49_RS17870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FDQ49_RS17895	COG1309	transcriptional regulator
FDQ49_RS17910	COG1309	transcriptional regulator
FDQ49_RS17915	COG2831	hemolysin activation secretion protein
FDQ49_RS17920	COG3210	domain, Protein
FDQ49_RS17960	COG2188	Transcriptional regulator
FDQ49_RS17965	COG0583	DNA-binding transcription factor activity
FDQ49_RS17990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDQ49_RS18005	COG2271	Major facilitator Superfamily
FDQ49_RS18015	COG1566	PFAM secretion protein HlyD family protein
FDQ49_RS18030	COG1012	belongs to the aldehyde dehydrogenase family