locus-tag	class	description
DIW83_RS00010	COG0592	DNA-directed DNA polymerase activity
DIW83_RS00020	COG0187	DNA topoisomerase II activity
DIW83_RS00030	COG0586	Pfam SNARE associated Golgi protein
DIW83_RS00035	COG0488	(ABC) transporter
DIW83_RS00060	COG0596	Alpha beta hydrolase
DIW83_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DIW83_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIW83_RS00115	COG0733	neurotransmitter:sodium symporter activity
DIW83_RS00155	COG2233	PERMEase
DIW83_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS00205	COG2814	Major facilitator Superfamily
DIW83_RS00210	COG0656	L-ascorbic acid biosynthetic process
DIW83_RS00215	COG0583	DNA-binding transcription factor activity
DIW83_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIW83_RS00235	COG1064	alcohol dehydrogenase
DIW83_RS00255	COG1194	a g-specific adenine glycosylase
DIW83_RS00270	COG5487	UPF0391 membrane protein
DIW83_RS00275	COG2983	Belongs to the UPF0260 family
DIW83_RS00280	COG2133	pyrroloquinoline quinone binding
DIW83_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DIW83_RS00290	COG2116	formate transmembrane transporter activity
DIW83_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIW83_RS00315	COG1335	isochorismatase
DIW83_RS00320	COG0385	Bile acid
DIW83_RS00325	COG0534	Mate efflux family protein
DIW83_RS00330	COG1683	Conserved Protein
DIW83_RS00350	COG0625	glutathione transferase activity
DIW83_RS00360	COG1113	amino acid transport
DIW83_RS00370	COG0523	cobalamin synthesis protein
DIW83_RS00380	COG2188	Transcriptional regulator
DIW83_RS00410	COG0010	Belongs to the arginase family
DIW83_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DIW83_RS00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIW83_RS00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DIW83_RS00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DIW83_RS00555	COG0436	Aminotransferase
DIW83_RS00560	COG2733	membrane
DIW83_RS00575	COG2918	glutathione biosynthetic process
DIW83_RS00590	COG1388	LysM domain
DIW83_RS00590	COG3409	Peptidoglycan-binding domain 1 protein
DIW83_RS00590	COG5632	N-Acetylmuramoyl-L-alanine amidase
DIW83_RS00620	COG3150	esterase
DIW83_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DIW83_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIW83_RS00650	COG2233	PERMEase
DIW83_RS00655	COG2351	hydroxyisourate hydrolase activity
DIW83_RS00690	COG3706	GGDEF domain
DIW83_RS00705	COG1393	Belongs to the ArsC family
DIW83_RS00710	COG0708	Exodeoxyribonuclease III
DIW83_RS00730	COG0189	ligase activity
DIW83_RS00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DIW83_RS00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DIW83_RS00780	COG4942	peptidase
DIW83_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIW83_RS00800	COG2119	membrane
DIW83_RS00805	COG0426	domain, Protein
DIW83_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIW83_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DIW83_RS00850	COG1902	pentaerythritol trinitrate reductase activity
DIW83_RS00855	COG1519	Transferase
DIW83_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DIW83_RS00865	COG0668	transmembrane transport
DIW83_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIW83_RS00880	COG1335	isochorismatase
DIW83_RS00885	COG1522	sequence-specific DNA binding
DIW83_RS00910	COG0784	Response regulator, receiver
DIW83_RS00910	COG2198	Histidine kinase
DIW83_RS00910	COG2205	protein histidine kinase activity
DIW83_RS00915	COG3162	membrane
DIW83_RS00920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIW83_RS00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DIW83_RS00955	COG1309	transcriptional regulator
DIW83_RS00975	COG0352	thiamine-phosphate diphosphorylase activity
DIW83_RS00975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DIW83_RS00975	COG0351	phosphomethylpyrimidine kinase
DIW83_RS00985	COG2814	Major facilitator Superfamily
DIW83_RS01000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DIW83_RS01010	COG1113	amino acid transport
DIW83_RS01020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DIW83_RS01025	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS01035	COG1335	isochorismatase
DIW83_RS01070	COG2814	Major facilitator Superfamily
DIW83_RS01075	COG0583	DNA-binding transcription factor activity
DIW83_RS01095	COG0667	Aldo Keto reductase
DIW83_RS01130	COG1733	regulation of RNA biosynthetic process
DIW83_RS01140	COG2249	NAD(P)H dehydrogenase (quinone) activity
DIW83_RS01165	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DIW83_RS01170	COG2207	Transcriptional regulator
DIW83_RS01230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DIW83_RS01255	COG4619	ABC transporter
DIW83_RS01275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DIW83_RS01305	COG0427	acetyl-CoA hydrolase
DIW83_RS01335	COG0659	secondary active sulfate transmembrane transporter activity
DIW83_RS01340	COG4221	oxidoreductase activity
DIW83_RS01345	COG2873	o-acetylhomoserine
DIW83_RS01350	COG0028	Belongs to the TPP enzyme family
DIW83_RS01355	COG0488	(ABC) transporter
DIW83_RS01420	COG0833	amino acid
DIW83_RS01445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DIW83_RS01465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIW83_RS01470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DIW83_RS01485	COG2226	methyltransferase
DIW83_RS01535	COG0070	glutamate synthase
DIW83_RS01535	COG0067	glutamate synthase
DIW83_RS01535	COG0069	glutamate synthase activity
DIW83_RS01540	COG0493	'glutamate synthase
DIW83_RS01550	COG1704	LemA family
DIW83_RS01555	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DIW83_RS01575	COG3307	-O-antigen
DIW83_RS01595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIW83_RS01610	COG0194	GDP metabolic process
DIW83_RS01660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DIW83_RS01680	COG5380	lipid catabolic process
DIW83_RS01685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DIW83_RS01700	COG5006	permease, DMT superfamily
DIW83_RS01705	COG5006	permease, DMT superfamily
DIW83_RS01710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIW83_RS01715	COG0277	FAD linked oxidase domain protein
DIW83_RS01730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DIW83_RS01735	COG2249	NAD(P)H dehydrogenase (quinone) activity
DIW83_RS01750	COG1289	transmembrane transporter activity
DIW83_RS01760	COG0628	permease
DIW83_RS01765	COG1192	Involved in chromosome partitioning
DIW83_RS01795	COG0833	amino acid
DIW83_RS01800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIW83_RS01805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIW83_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS01855	COG0583	DNA-binding transcription factor activity
DIW83_RS01875	COG1106	Psort location Cytoplasmic, score
DIW83_RS01910	COG0517	IMP dehydrogenase activity
DIW83_RS01915	COG1983	PspC domain protein
DIW83_RS01925	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS01940	COG0408	coproporphyrinogen oxidase activity
DIW83_RS01965	COG1127	ABC transporter
DIW83_RS01970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DIW83_RS01980	COG2854	intermembrane phospholipid transfer
DIW83_RS01990	COG0598	Magnesium transport protein CorA
DIW83_RS02000	COG0494	nUDIX hydrolase
DIW83_RS02005	COG1040	competence protein
DIW83_RS02010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DIW83_RS02030	COG1946	Acyl-CoA thioesterase
DIW83_RS02035	COG1301	dicarboxylic acid transport
DIW83_RS02050	COG1959	2 iron, 2 sulfur cluster binding
DIW83_RS02055	COG1017	nitric oxide dioxygenase activity
DIW83_RS02055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIW83_RS02060	COG0433	COG0433 Predicted ATPase
DIW83_RS02065	COG0626	cystathionine gamma-synthase activity
DIW83_RS02080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DIW83_RS02085	COG0088	Forms part of the polypeptide exit tunnel
DIW83_RS02220	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS02225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DIW83_RS02255	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DIW83_RS02260	COG0339	signal peptide processing
DIW83_RS02265	COG0557	exoribonuclease II activity
DIW83_RS02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
DIW83_RS02320	COG2207	Transcriptional regulator
DIW83_RS02330	COG1295	ribonuclease BN
DIW83_RS02365	COG1702	phosphate starvation-inducible protein PhoH
DIW83_RS02375	COG1196	nuclear chromosome segregation
DIW83_RS02375	COG0741	lytic transglycosylase activity
DIW83_RS02375	COG0739	heme binding
DIW83_RS02405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DIW83_RS02410	COG1183	phosphatidylcholine synthase activity
DIW83_RS02460	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS02465	COG1309	transcriptional regulator
DIW83_RS02480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIW83_RS02485	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS02535	COG2969	positive regulation of protein catabolic process
DIW83_RS02545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DIW83_RS02550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DIW83_RS02555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DIW83_RS02560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DIW83_RS02565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DIW83_RS02585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DIW83_RS02595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIW83_RS02600	COG1408	metallophosphoesterase
DIW83_RS02610	COG2199	diguanylate cyclase activity
DIW83_RS02645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIW83_RS02670	COG1607	acyl-coa hydrolase
DIW83_RS02705	COG2350	Protein conserved in bacteria
DIW83_RS02715	COG0613	PHP domain protein
DIW83_RS02720	COG3781	membrane
DIW83_RS02730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DIW83_RS02735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIW83_RS02745	COG1862	Preprotein translocase
DIW83_RS02795	COG0629	single-stranded DNA binding
DIW83_RS02960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIW83_RS02960	COG0784	Response regulator, receiver
DIW83_RS02960	COG2198	Histidine kinase
DIW83_RS02960	COG2205	protein histidine kinase activity
DIW83_RS02965	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DIW83_RS02980	COG2194	sulfuric ester hydrolase activity
DIW83_RS02990	COG0726	polysaccharide deacetylase
DIW83_RS02995	COG0463	Glycosyl transferase, family 2
DIW83_RS03000	COG0438	transferase activity, transferring glycosyl groups
DIW83_RS03070	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS03075	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS03085	COG2205	protein histidine kinase activity
DIW83_RS03090	COG0745	RESPONSE REGULATOR receiver
DIW83_RS03095	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DIW83_RS03115	COG2096	Adenosyltransferase
DIW83_RS03170	COG0285	dihydrofolate synthase activity
DIW83_RS03190	COG0450	alkyl hydroperoxide reductase
DIW83_RS03210	COG0477	Major facilitator Superfamily
DIW83_RS03215	COG1272	protein, Hemolysin III
DIW83_RS03225	COG2153	protein acetylation
DIW83_RS03245	COG0183	Belongs to the thiolase family
DIW83_RS03250	COG2207	Transcriptional regulator
DIW83_RS03270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIW83_RS03290	COG0183	Belongs to the thiolase family
DIW83_RS03300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DIW83_RS03300	COG2885	chlorophyll binding
DIW83_RS03305	COG1690	Belongs to the RtcB family
DIW83_RS03310	COG0833	amino acid
DIW83_RS03320	COG2233	PERMEase
DIW83_RS03325	COG1217	gtp-binding protein TYPA
DIW83_RS03350	COG2094	Belongs to the DNA glycosylase MPG family
DIW83_RS03355	COG4772	TonB-dependent receptor
DIW83_RS03360	COG1902	pentaerythritol trinitrate reductase activity
DIW83_RS03365	COG0679	Auxin Efflux Carrier
DIW83_RS03375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DIW83_RS03380	COG0354	folic acid binding
DIW83_RS03390	COG3189	MarR family transcriptional regulator
DIW83_RS03395	COG2824	Alkylphosphonate utilization operon protein PhnA
DIW83_RS03400	COG3422	double-strand break repair
DIW83_RS03440	COG0840	transmembrane signaling receptor activity
DIW83_RS03470	COG2832	Protein of unknown function (DUF454)
DIW83_RS03475	COG1376	ErfK ybiS ycfS ynhG family protein
DIW83_RS03515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DIW83_RS03525	COG1289	transmembrane transporter activity
DIW83_RS03530	COG2814	Major facilitator Superfamily
DIW83_RS03555	COG1115	amino acid carrier protein
DIW83_RS03560	COG1752	Esterase of the alpha-beta hydrolase superfamily
DIW83_RS03565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DIW83_RS03570	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DIW83_RS03600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIW83_RS03610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIW83_RS03615	COG1077	Cell shape determining protein MreB Mrl
DIW83_RS03620	COG1792	Involved in formation and maintenance of cell shape
DIW83_RS03625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DIW83_RS03630	COG0424	maF-like protein
DIW83_RS03635	COG1530	ribonuclease E activity
DIW83_RS03645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIW83_RS03665	COG2249	NAD(P)H dehydrogenase (quinone) activity
DIW83_RS03690	COG2207	Transcriptional regulator
DIW83_RS03855	COG0582	viral genome integration into host DNA
DIW83_RS03875	COG3046	protein related to deoxyribodipyrimidine photolyase
DIW83_RS03880	COG2816	NAD+ diphosphatase activity
DIW83_RS03885	COG1113	amino acid transport
DIW83_RS03890	COG2828	Protein conserved in bacteria
DIW83_RS03895	COG0142	geranyltranstransferase activity
DIW83_RS03900	COG2315	Protein conserved in bacteria
DIW83_RS03915	COG1752	Esterase of the alpha-beta hydrolase superfamily
DIW83_RS03935	COG2194	sulfuric ester hydrolase activity
DIW83_RS03940	COG0745	RESPONSE REGULATOR receiver
DIW83_RS03945	COG0642	Histidine kinase
DIW83_RS03955	COG0004	ammonium transporteR
DIW83_RS03965	COG0583	DNA-binding transcription factor activity
DIW83_RS03985	COG0525	valine-tRNA ligase activity
DIW83_RS03995	COG0525	valine-tRNA ligase activity
DIW83_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS04015	COG0393	Putative heavy-metal-binding
DIW83_RS04020	COG0393	Putative heavy-metal-binding
DIW83_RS04025	COG1538	Outer membrane efflux protein
DIW83_RS04035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS04040	COG0671	phosphoesterase, PA-phosphatase related
DIW83_RS04070	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DIW83_RS04085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DIW83_RS04085	COG1648	precorrin-2 dehydrogenase activity
DIW83_RS04090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DIW83_RS04095	COG1733	regulation of RNA biosynthetic process
DIW83_RS04105	COG0531	amino acid
DIW83_RS04120	COG0321	lipoyl(octanoyl) transferase activity
DIW83_RS04125	COG2921	Belongs to the UPF0250 family
DIW83_RS04160	COG2009	succinate dehydrogenase
DIW83_RS04165	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DIW83_RS04170	COG1053	succinate dehydrogenase
DIW83_RS04175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DIW83_RS04200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIW83_RS04220	COG2354	Protein conserved in bacteria
DIW83_RS04225	COG2321	neutral zinc metallopeptidase
DIW83_RS04255	COG0589	response to stress
DIW83_RS04265	COG0251	oxidation-reduction process
DIW83_RS04270	COG1309	transcriptional regulator
DIW83_RS04285	COG0505	Belongs to the CarA family
DIW83_RS04315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIW83_RS04320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DIW83_RS04370	COG0477	Major facilitator Superfamily
DIW83_RS04375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DIW83_RS04390	COG1597	lipid kinase activity
DIW83_RS04395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DIW83_RS04415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIW83_RS04420	COG0584	glycerophosphoryl diester phosphodiesterase
DIW83_RS04440	COG0741	lytic transglycosylase activity
DIW83_RS04465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DIW83_RS04480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIW83_RS04490	COG3811	Belongs to the UPF0386 family
DIW83_RS04550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS04555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIW83_RS04560	COG0778	Nitroreductase
DIW83_RS04565	COG0300	oxidoreductase activity
DIW83_RS04575	COG1929	Belongs to the glycerate kinase type-1 family
DIW83_RS04580	COG0243	molybdopterin cofactor binding
DIW83_RS04585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DIW83_RS04600	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DIW83_RS04615	COG1113	amino acid transport
DIW83_RS04620	COG1113	amino acid transport
DIW83_RS04630	COG0019	diaminopimelate decarboxylase activity
DIW83_RS04640	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS04645	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DIW83_RS04665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIW83_RS04675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DIW83_RS04685	COG0463	Glycosyl transferase, family 2
DIW83_RS04705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS04735	COG4591	ABC-type transport system involved in lipoprotein release permease component
DIW83_RS04740	COG1136	(ABC) transporter
DIW83_RS04755	COG0616	signal peptide processing
DIW83_RS04755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DIW83_RS04760	COG0596	Alpha beta hydrolase
DIW83_RS04765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DIW83_RS04775	COG0628	permease
DIW83_RS04810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIW83_RS04830	COG0823	Involved in the tonB-independent uptake of proteins
DIW83_RS04850	COG0824	Thioesterase
DIW83_RS04855	COG1473	amidohydrolase
DIW83_RS04875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIW83_RS04875	COG0047	phosphoribosylformylglycinamidine synthase activity
DIW83_RS04880	COG2814	Major facilitator Superfamily
DIW83_RS04895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIW83_RS04905	COG1051	belongs to the nudix hydrolase family
DIW83_RS04905	COG1056	cytidyltransferase-related domain
DIW83_RS04920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DIW83_RS04935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DIW83_RS04940	COG0602	queuosine metabolic process
DIW83_RS04950	COG4625	pathogenesis
DIW83_RS04955	COG0583	DNA-binding transcription factor activity
DIW83_RS04960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DIW83_RS04965	COG4208	sulfate ABC transporter
DIW83_RS04970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DIW83_RS04980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DIW83_RS04985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIW83_RS04990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIW83_RS05010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIW83_RS05020	COG0481	GTPase activity
DIW83_RS05025	COG0681	Belongs to the peptidase S26 family
DIW83_RS05040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DIW83_RS05050	COG1381	Involved in DNA repair and RecF pathway recombination
DIW83_RS05055	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DIW83_RS05065	COG4221	oxidoreductase activity
DIW83_RS05095	COG0436	Aminotransferase
DIW83_RS05115	COG0556	nucleotide-excision repair
DIW83_RS05170	COG2070	2-Nitropropane dioxygenase
DIW83_RS05200	COG1215	transferase activity, transferring glycosyl groups
DIW83_RS05215	COG0415	Belongs to the DNA photolyase family
DIW83_RS05225	COG1252	NADH dehydrogenase
DIW83_RS05230	COG1686	Belongs to the peptidase S11 family
DIW83_RS05245	COG1187	pseudouridine synthase activity
DIW83_RS05270	COG0477	Major facilitator Superfamily
DIW83_RS05275	COG0583	DNA-binding transcription factor activity
DIW83_RS05280	COG1823	symporter activity
DIW83_RS05290	COG0612	Peptidase, M16
DIW83_RS05315	COG0352	thiamine-phosphate diphosphorylase activity
DIW83_RS05350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIW83_RS05375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DIW83_RS05380	COG0076	glutamate decarboxylase activity
DIW83_RS05390	COG1522	sequence-specific DNA binding
DIW83_RS05395	COG3961	Belongs to the TPP enzyme family
DIW83_RS05400	COG1113	amino acid transport
DIW83_RS05405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DIW83_RS05410	COG0573	inorganic phosphate transmembrane transporter activity
DIW83_RS05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DIW83_RS05425	COG0616	signal peptide processing
DIW83_RS05445	COG3647	Membrane
DIW83_RS05470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DIW83_RS05475	COG1686	Belongs to the peptidase S11 family
DIW83_RS05500	COG0583	DNA-binding transcription factor activity
DIW83_RS05505	COG1067	ATP-dependent peptidase activity
DIW83_RS05530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DIW83_RS05545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIW83_RS05550	COG1966	Carbon starvation protein
DIW83_RS05555	COG2879	small protein
DIW83_RS05605	COG2964	Protein conserved in bacteria
DIW83_RS05610	COG1741	Belongs to the pirin family
DIW83_RS05630	COG3739	integral membrane protein
DIW83_RS05650	COG0302	gtp cyclohydrolase
DIW83_RS05660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DIW83_RS05670	COG2840	Smr protein MutS2
DIW83_RS05695	COG0512	Glutamine amidotransferase of anthranilate synthase
DIW83_RS06020	COG0582	viral genome integration into host DNA
DIW83_RS06035	COG0174	glutamine synthetase
DIW83_RS06045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DIW83_RS06085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DIW83_RS06090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIW83_RS06095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIW83_RS06115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DIW83_RS06120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DIW83_RS06125	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DIW83_RS06140	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS06145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DIW83_RS06150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIW83_RS06160	COG2223	nitrite transmembrane transporter activity
DIW83_RS06170	COG0024	Methionine aminopeptidase
DIW83_RS06175	COG0052	Belongs to the universal ribosomal protein uS2 family
DIW83_RS06190	COG2207	Transcriptional regulator
DIW83_RS06215	COG2951	lytic endotransglycosylase activity
DIW83_RS06220	COG0772	Belongs to the SEDS family
DIW83_RS06235	COG0842	Transport permease protein
DIW83_RS06240	COG1131	(ABC) transporter
DIW83_RS06325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS06340	COG4215	(ABC) transporter
DIW83_RS06345	COG4160	amino acid transport
DIW83_RS06350	COG4598	ABC transporter
DIW83_RS06360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DIW83_RS06365	COG0826	peptidase U32
DIW83_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIW83_RS06375	COG0384	phenazine biosynthesis protein PhzF
DIW83_RS06385	COG1720	tRNA m6t6A37 methyltransferase activity
DIW83_RS06395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DIW83_RS06400	COG3111	PFAM Bacterial OB fold (BOF) protein
DIW83_RS06410	COG0642	Histidine kinase
DIW83_RS06420	COG0494	nUDIX hydrolase
DIW83_RS06430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIW83_RS06435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIW83_RS06440	COG3139	Protein of unknown function (DUF1315)
DIW83_RS06445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DIW83_RS06455	COG1301	dicarboxylic acid transport
DIW83_RS06460	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS06470	COG2819	hydrolase of the alpha beta superfamily
DIW83_RS06480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DIW83_RS06490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIW83_RS06495	COG2195	Cleaves the N-terminal amino acid of tripeptides
DIW83_RS06500	COG1234	tRNA 3'-trailer cleavage
DIW83_RS06525	COG2363	Small membrane protein
DIW83_RS06545	COG0513	Belongs to the DEAD box helicase family
DIW83_RS06555	COG0778	Nitroreductase
DIW83_RS06585	COG1286	toxin biosynthetic process
DIW83_RS06615	COG1610	YqeY-like protein
DIW83_RS06645	COG0515	serine threonine protein kinase
DIW83_RS06645	COG2815	serine threonine protein kinase
DIW83_RS06670	COG2831	hemolysin activation secretion protein
DIW83_RS06785	COG2226	methyltransferase
DIW83_RS06795	COG3111	PFAM Bacterial OB fold (BOF) protein
DIW83_RS06810	COG2801	Transposase and inactivated derivatives
DIW83_RS06825	COG3243	poly(R)-hydroxyalkanoic acid synthase
DIW83_RS06830	COG0786	glutamate:sodium symporter activity
DIW83_RS06835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DIW83_RS06835	COG0475	glutathione-regulated potassium exporter activity
DIW83_RS06840	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS06900	COG1073	alpha beta
DIW83_RS06910	COG0583	DNA-binding transcription factor activity
DIW83_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS06920	COG2207	Transcriptional regulator
DIW83_RS06955	COG2995	paraquat-inducible protein a
DIW83_RS06960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DIW83_RS06960	COG3008	intermembrane lipid transfer
DIW83_RS06970	COG2351	hydroxyisourate hydrolase activity
DIW83_RS07010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DIW83_RS07020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DIW83_RS07025	COG0642	Histidine kinase
DIW83_RS07030	COG0745	RESPONSE REGULATOR receiver
DIW83_RS07065	COG0625	glutathione transferase activity
DIW83_RS07080	COG1301	dicarboxylic acid transport
DIW83_RS07095	COG2011	ABC-type metal ion transport system permease component
DIW83_RS07100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIW83_RS07115	COG0151	Belongs to the GarS family
DIW83_RS07120	COG0138	bifunctional purine biosynthesis protein purh
DIW83_RS07125	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DIW83_RS07155	COG2308	Evidence 4 Homologs of previously reported genes of
DIW83_RS07165	COG1305	Transglutaminase-like
DIW83_RS07175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DIW83_RS07180	COG0305	Participates in initiation and elongation during chromosome replication
DIW83_RS07205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DIW83_RS07215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DIW83_RS07245	COG0726	polysaccharide deacetylase
DIW83_RS07245	COG1649	PFAM Uncharacterised BCR, COG1649
DIW83_RS07250	COG1215	transferase activity, transferring glycosyl groups
DIW83_RS07255	COG3658	cytochrome
DIW83_RS07265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIW83_RS07285	COG0583	DNA-binding transcription factor activity
DIW83_RS07305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIW83_RS07310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DIW83_RS07325	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS07330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIW83_RS07335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIW83_RS07360	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DIW83_RS07365	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DIW83_RS07370	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DIW83_RS07375	COG2205	protein histidine kinase activity
DIW83_RS07380	COG0745	RESPONSE REGULATOR receiver
DIW83_RS07385	COG0174	glutamine synthetase
DIW83_RS07405	COG0729	surface antigen
DIW83_RS07435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DIW83_RS07440	COG2814	Major facilitator Superfamily
DIW83_RS07450	COG0583	DNA-binding transcription factor activity
DIW83_RS07465	COG1187	pseudouridine synthase activity
DIW83_RS07485	COG0802	atpase or kinase
DIW83_RS07490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DIW83_RS07500	COG1923	regulation of RNA biosynthetic process
DIW83_RS07505	COG0697	spore germination
DIW83_RS07535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DIW83_RS07535	COG0519	Catalyzes the synthesis of GMP from XMP
DIW83_RS07540	COG4302	ethanolamine ammonia-lyase activity
DIW83_RS07545	COG4303	Ethanolamine ammonia lyase large subunit
DIW83_RS07550	COG0531	amino acid
DIW83_RS07570	COG1454	alcohol dehydrogenase
DIW83_RS07575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIW83_RS07585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DIW83_RS07605	COG0308	aminopeptidase N
DIW83_RS07645	COG1605	Chorismate mutase
DIW83_RS07690	COG4264	IucA IucC family
DIW83_RS07695	COG2423	ornithine cyclodeaminase activity
DIW83_RS07700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DIW83_RS07710	COG0668	transmembrane transport
DIW83_RS07755	COG0488	(ABC) transporter
DIW83_RS07760	COG0589	response to stress
DIW83_RS07785	COG3135	benzoate transporter
DIW83_RS07790	COG1522	sequence-specific DNA binding
DIW83_RS07800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DIW83_RS07805	COG0583	DNA-binding transcription factor activity
DIW83_RS07815	COG0183	Belongs to the thiolase family
DIW83_RS07825	COG2030	dehydratase
DIW83_RS07830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIW83_RS07855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIW83_RS07865	COG0824	Thioesterase
DIW83_RS07870	COG1454	alcohol dehydrogenase
DIW83_RS07880	COG1335	isochorismatase
DIW83_RS07895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIW83_RS07925	COG0069	glutamate synthase activity
DIW83_RS07960	COG2814	Major facilitator Superfamily
DIW83_RS07970	COG0439	Biotin carboxylase
DIW83_RS07975	COG0511	ligase activity, forming carbon-carbon bonds
DIW83_RS07995	COG1116	anion transmembrane transporter activity
DIW83_RS07995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DIW83_RS08000	COG0745	RESPONSE REGULATOR receiver
DIW83_RS08010	COG2146	nitrite reductase [NAD(P)H] activity
DIW83_RS08010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIW83_RS08015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIW83_RS08020	COG0243	molybdopterin cofactor binding
DIW83_RS08030	COG0243	molybdopterin cofactor binding
DIW83_RS08035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DIW83_RS08050	COG0315	cyclic pyranopterin monophosphate synthase activity
DIW83_RS08050	COG0521	Mo-molybdopterin cofactor biosynthetic process
DIW83_RS08055	COG0303	'Molybdopterin
DIW83_RS08065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIW83_RS08070	COG0697	spore germination
DIW83_RS08090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DIW83_RS08095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIW83_RS08155	COG2204	response regulator
DIW83_RS08160	COG3852	Histidine kinase
DIW83_RS08185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIW83_RS08190	COG0575	Belongs to the CDS family
DIW83_RS08225	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DIW83_RS08240	COG2137	regulation of response to DNA damage stimulus
DIW83_RS08250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DIW83_RS08255	COG1011	Hydrolase
DIW83_RS08275	COG1522	sequence-specific DNA binding
DIW83_RS08300	COG0659	secondary active sulfate transmembrane transporter activity
DIW83_RS08305	COG2135	peptidase activity
DIW83_RS08320	COG5001	Diguanylate cyclase
DIW83_RS08320	COG3300	MHYT domain
DIW83_RS08335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DIW83_RS08335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DIW83_RS08335	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DIW83_RS08340	COG1105	Belongs to the carbohydrate kinase PfkB family
DIW83_RS08345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIW83_RS08345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIW83_RS08375	COG0024	Methionine aminopeptidase
DIW83_RS08380	COG0583	DNA-binding transcription factor activity
DIW83_RS08390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DIW83_RS08395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIW83_RS08400	COG0516	GMP reductase activity
DIW83_RS08400	COG0517	IMP dehydrogenase activity
DIW83_RS08425	COG0552	protein localization to endoplasmic reticulum
DIW83_RS08435	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DIW83_RS08450	COG4890	Cyd operon protein YbgT
DIW83_RS08455	COG1294	oxidase, subunit
DIW83_RS08480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIW83_RS08485	COG4774	siderophore transport
DIW83_RS08500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DIW83_RS08505	COG0569	domain protein
DIW83_RS08510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DIW83_RS08540	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DIW83_RS08545	COG0542	response to heat
DIW83_RS08570	COG1902	pentaerythritol trinitrate reductase activity
DIW83_RS08570	COG0446	pyridine nucleotide-disulphide oxidoreductase
DIW83_RS08610	COG2323	membrane
DIW83_RS08620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DIW83_RS08630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIW83_RS08635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DIW83_RS08640	COG0183	Belongs to the thiolase family
DIW83_RS08645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DIW83_RS08650	COG0596	Alpha beta hydrolase
DIW83_RS08655	COG2271	Major facilitator Superfamily
DIW83_RS08660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIW83_RS08665	COG3485	protocatechuate 3,4-dioxygenase
DIW83_RS08670	COG3485	protocatechuate 3,4-dioxygenase
DIW83_RS08675	COG0710	3-dehydroquinate dehydratase activity
DIW83_RS08680	COG3420	alginic acid biosynthetic process
DIW83_RS08685	COG3659	wide pore channel activity
DIW83_RS08690	COG4993	Dehydrogenase
DIW83_RS08700	COG2391	methyltransferase activity
DIW83_RS08715	COG1414	Transcriptional regulator
DIW83_RS08720	COG0583	DNA-binding transcription factor activity
DIW83_RS08750	COG2814	Major facilitator Superfamily
DIW83_RS08760	COG0154	amidase activity
DIW83_RS08780	COG4638	Rieske (2fe-2S)
DIW83_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS08800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIW83_RS08810	COG3733	amine oxidase
DIW83_RS08820	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS08825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIW83_RS08830	COG0183	Belongs to the thiolase family
DIW83_RS08835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DIW83_RS08840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIW83_RS08850	COG4829	muconolactone delta-isomerase
DIW83_RS08855	COG4948	Mandelate Racemase Muconate Lactonizing
DIW83_RS08860	COG0583	DNA-binding transcription factor activity
DIW83_RS08870	COG2186	Transcriptional regulator
DIW83_RS08890	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS08915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIW83_RS08925	COG0789	Transcriptional regulator
DIW83_RS08940	COG1309	transcriptional regulator
DIW83_RS08960	COG1309	transcriptional regulator
DIW83_RS08965	COG2831	hemolysin activation secretion protein
DIW83_RS08970	COG3210	domain, Protein
DIW83_RS09015	COG2188	Transcriptional regulator
DIW83_RS09020	COG0583	DNA-binding transcription factor activity
DIW83_RS09040	COG1566	PFAM secretion protein HlyD family protein
DIW83_RS09055	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS09060	COG0129	dihydroxy-acid dehydratase activity
DIW83_RS09070	COG0583	DNA-binding transcription factor activity
DIW83_RS09075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIW83_RS09085	COG2084	Dehydrogenase
DIW83_RS09090	COG2207	Transcriptional regulator
DIW83_RS09105	COG1064	alcohol dehydrogenase
DIW83_RS09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIW83_RS09120	COG1120	ATPase activity
DIW83_RS09140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIW83_RS09215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DIW83_RS09240	COG2274	protein secretion by the type I secretion system
DIW83_RS09255	COG1064	alcohol dehydrogenase
DIW83_RS09260	COG4221	oxidoreductase activity
DIW83_RS09265	COG1073	alpha beta
DIW83_RS09285	COG1309	transcriptional regulator
DIW83_RS09295	COG2205	protein histidine kinase activity
DIW83_RS09300	COG0745	RESPONSE REGULATOR receiver
DIW83_RS09305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS09310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIW83_RS09315	COG1538	Outer membrane efflux protein
DIW83_RS09325	COG2801	Transposase and inactivated derivatives
DIW83_RS09340	COG3539	Fimbrial protein
DIW83_RS09365	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DIW83_RS09375	COG0753	catalase activity
DIW83_RS09395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIW83_RS09460	COG4771	TonB-dependent receptor
DIW83_RS09465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIW83_RS09470	COG1535	isochorismatase
DIW83_RS09470	COG3433	isochorismatase activity
DIW83_RS09475	COG1021	2,3-dihydroxybenzoate-AMP ligase
DIW83_RS09480	COG1169	isochorismate synthase
DIW83_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS09495	COG3251	PFAM MbtH domain protein
DIW83_RS09500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIW83_RS09530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DIW83_RS09535	COG4149	molybdate abc transporter
DIW83_RS09540	COG0725	ABC transporter, periplasmic molybdate-binding protein
DIW83_RS09550	COG4638	Rieske (2fe-2S)
DIW83_RS09555	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DIW83_RS09560	COG0543	2 iron, 2 sulfur cluster binding
DIW83_RS09560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIW83_RS09575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIW83_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS09600	COG2207	Transcriptional regulator
DIW83_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS09610	COG2610	gluconate transmembrane transporter activity
DIW83_RS09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIW83_RS09650	COG0583	DNA-binding transcription factor activity
DIW83_RS09665	COG2031	fatty acid transporter
DIW83_RS09670	COG0183	Belongs to the thiolase family
DIW83_RS09675	COG0583	DNA-binding transcription factor activity
DIW83_RS09680	COG0583	DNA-binding transcription factor activity
DIW83_RS09695	COG1027	Aspartate ammonia-lyase
DIW83_RS09705	COG0477	Major facilitator Superfamily
DIW83_RS09725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIW83_RS09730	COG4521	taurine ABC transporter
DIW83_RS09745	COG2188	Transcriptional regulator
DIW83_RS09755	COG2207	Transcriptional regulator
DIW83_RS09755	COG3708	Transcriptional regulator
DIW83_RS09770	COG0730	response to heat
DIW83_RS09780	COG3453	Protein conserved in bacteria
DIW83_RS09780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIW83_RS09790	COG3781	membrane
DIW83_RS09795	COG1063	alcohol dehydrogenase
DIW83_RS09805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIW83_RS09810	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIW83_RS09815	COG0022	dehydrogenase e1 component
DIW83_RS09820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DIW83_RS09825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DIW83_RS09855	COG0133	tryptophan synthase activity
DIW83_RS09870	COG2226	methyltransferase
DIW83_RS09925	COG0842	Transport permease protein
DIW83_RS09930	COG0842	Transport permease protein
DIW83_RS09935	COG1131	(ABC) transporter
DIW83_RS09950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DIW83_RS09955	COG4773	Receptor
DIW83_RS09975	COG0730	response to heat
DIW83_RS09980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DIW83_RS09990	COG4772	TonB-dependent receptor
DIW83_RS10005	COG0406	alpha-ribazole phosphatase activity
DIW83_RS10010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DIW83_RS10035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DIW83_RS10050	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS10055	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS10060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIW83_RS10065	COG2207	Transcriptional regulator
DIW83_RS10070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DIW83_RS10075	COG0776	regulation of translation
DIW83_RS10100	COG0822	iron-sulfur transferase activity
DIW83_RS10105	COG0316	Belongs to the HesB IscA family
DIW83_RS10135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DIW83_RS10155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DIW83_RS10160	COG0702	epimerase
DIW83_RS10190	COG4172	Belongs to the ABC transporter superfamily
DIW83_RS10195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIW83_RS10200	COG0601	transmembrane transport
DIW83_RS10205	COG0339	signal peptide processing
DIW83_RS10230	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DIW83_RS10255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DIW83_RS10260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DIW83_RS10275	COG2431	L-lysine efflux transmembrane transporter activity
DIW83_RS10290	COG0776	regulation of translation
DIW83_RS10355	COG0084	hydrolase, TatD family'
DIW83_RS10375	COG1663	tetraacyldisaccharide 4'-kinase activity
DIW83_RS10380	COG1132	(ABC) transporter
DIW83_RS10390	COG0811	peptide transport
DIW83_RS10395	COG1475	DNA binding
DIW83_RS10400	COG1192	Involved in chromosome partitioning
DIW83_RS10410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DIW83_RS10425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DIW83_RS10430	COG0191	fructose-bisphosphate aldolase activity
DIW83_RS10450	COG0424	maF-like protein
DIW83_RS10455	COG2850	peptidyl-arginine hydroxylation
DIW83_RS10465	COG0640	Transcriptional regulator
DIW83_RS10475	COG3619	membrane
DIW83_RS10480	COG3122	Protein conserved in bacteria
DIW83_RS10485	COG1132	(ABC) transporter
DIW83_RS10505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DIW83_RS10510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIW83_RS10520	COG0506	proline dehydrogenase activity
DIW83_RS10520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DIW83_RS10520	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DIW83_RS10525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DIW83_RS10540	COG3698	Phosphodiester glycosidase
DIW83_RS10550	COG2353	YceI-like domain
DIW83_RS10675	COG4695	Portal protein
DIW83_RS10735	COG0582	viral genome integration into host DNA
DIW83_RS10740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DIW83_RS10780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DIW83_RS10780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DIW83_RS10805	COG3539	Fimbrial protein
DIW83_RS10810	COG3121	Chaperone
DIW83_RS10840	COG0697	spore germination
DIW83_RS10850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DIW83_RS10860	COG0583	DNA-binding transcription factor activity
DIW83_RS10880	COG1309	transcriptional regulator
DIW83_RS10895	COG1522	sequence-specific DNA binding
DIW83_RS10905	COG1126	abc transporter atp-binding protein
DIW83_RS10910	COG0765	amino acid transport
DIW83_RS10915	COG0765	amino acid transport
DIW83_RS10945	COG1464	Belongs to the NlpA lipoprotein family
DIW83_RS10955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIW83_RS10960	COG2011	ABC-type metal ion transport system permease component
DIW83_RS10965	COG0012	GTP binding
DIW83_RS10990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DIW83_RS11020	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS11030	COG0386	Belongs to the glutathione peroxidase family
DIW83_RS11040	COG0436	Aminotransferase
DIW83_RS11045	COG1301	dicarboxylic acid transport
DIW83_RS11080	COG3634	alkyl hydroperoxide reductase activity
DIW83_RS11095	COG0583	DNA-binding transcription factor activity
DIW83_RS11100	COG0798	PFAM Bile acid sodium symporter
DIW83_RS11105	COG0640	Transcriptional regulator
DIW83_RS11120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DIW83_RS11130	COG0583	DNA-binding transcription factor activity
DIW83_RS11140	COG1953	Uracil, thiamine, allantoin
DIW83_RS11150	COG2175	clavaminate synthase activity
DIW83_RS11155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIW83_RS11160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DIW83_RS11165	COG4521	taurine ABC transporter
DIW83_RS11175	COG0477	Major facilitator Superfamily
DIW83_RS11200	COG1271	oxidase subunit
DIW83_RS11205	COG1294	oxidase, subunit
DIW83_RS11215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIW83_RS11235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DIW83_RS11255	COG3052	prosthetic group binding
DIW83_RS11260	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DIW83_RS11285	COG1346	cytolysis
DIW83_RS11295	COG0583	DNA-binding transcription factor activity
DIW83_RS11300	COG0625	glutathione transferase activity
DIW83_RS11305	COG0625	glutathione transferase activity
DIW83_RS11310	COG0583	DNA-binding transcription factor activity
DIW83_RS11325	COG1045	serine acetyltransferase
DIW83_RS11335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DIW83_RS11340	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS11355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIW83_RS11360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIW83_RS11365	COG1126	abc transporter atp-binding protein
DIW83_RS11370	COG0765	amino acid transport
DIW83_RS11375	COG0765	amino acid transport
DIW83_RS11395	COG2205	protein histidine kinase activity
DIW83_RS11395	COG0784	Response regulator, receiver
DIW83_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS11490	COG0583	DNA-binding transcription factor activity
DIW83_RS11510	COG0318	PFAM AMP-dependent synthetase and ligase
DIW83_RS11515	COG1309	transcriptional regulator
DIW83_RS11520	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS11525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIW83_RS11530	COG1024	Enoyl-CoA hydratase
DIW83_RS11535	COG4770	biotin carboxylase activity
DIW83_RS11545	COG0583	DNA-binding transcription factor activity
DIW83_RS11560	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS11570	COG2814	Major facilitator Superfamily
DIW83_RS11580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DIW83_RS11585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIW83_RS11590	COG2814	Major facilitator Superfamily
DIW83_RS11595	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS11600	COG1024	Enoyl-CoA hydratase
DIW83_RS11605	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS11610	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIW83_RS11615	COG0183	Belongs to the thiolase family
DIW83_RS11630	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS11635	COG2192	nodulation
DIW83_RS11650	COG1024	Enoyl-CoA hydratase
DIW83_RS11665	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS11670	COG2814	Major facilitator Superfamily
DIW83_RS11675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIW83_RS11680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DIW83_RS11695	COG3842	ATPase activity
DIW83_RS11700	COG1840	ABC-type Fe3 transport system, periplasmic component
DIW83_RS11715	COG1414	Transcriptional regulator
DIW83_RS11725	COG0583	DNA-binding transcription factor activity
DIW83_RS11730	COG3038	cytochrome b561
DIW83_RS11735	COG0753	catalase activity
DIW83_RS11740	COG1733	regulation of RNA biosynthetic process
DIW83_RS11770	COG2050	protein possibly involved in aromatic compounds catabolism
DIW83_RS11780	COG3327	negative regulation of DNA-templated transcription, initiation
DIW83_RS11785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DIW83_RS11790	COG0183	Belongs to the thiolase family
DIW83_RS11795	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIW83_RS11800	COG1024	Enoyl-CoA hydratase
DIW83_RS11805	COG1024	Enoyl-CoA hydratase
DIW83_RS11810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIW83_RS11815	COG2151	metal-sulfur cluster biosynthetic enzyme
DIW83_RS11820	COG3396	Phenylacetate-CoA oxygenase
DIW83_RS11825	COG3460	Phenylacetate-CoA oxygenase
DIW83_RS11830	COG3396	Phenylacetate-CoA oxygenase
DIW83_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS11835	COG2030	dehydratase
DIW83_RS11840	COG1760	l-serine dehydratase
DIW83_RS11845	COG0531	amino acid
DIW83_RS11850	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS11875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIW83_RS11895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIW83_RS11910	COG0789	Transcriptional regulator
DIW83_RS11920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DIW83_RS11935	COG2807	transmembrane transport
DIW83_RS11940	COG0590	tRNA wobble adenosine to inosine editing
DIW83_RS11985	COG2885	chlorophyll binding
DIW83_RS12045	COG0477	Major facilitator Superfamily
DIW83_RS12060	COG1116	anion transmembrane transporter activity
DIW83_RS12065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIW83_RS12075	COG0864	Transcriptional regulator
DIW83_RS12085	COG1733	regulation of RNA biosynthetic process
DIW83_RS12090	COG2249	NAD(P)H dehydrogenase (quinone) activity
DIW83_RS12095	COG0439	Biotin carboxylase
DIW83_RS12110	COG1063	alcohol dehydrogenase
DIW83_RS12150	COG0038	chloride channel
DIW83_RS12155	COG4770	biotin carboxylase activity
DIW83_RS12175	COG1914	H( )-stimulated, divalent metal cation uptake system
DIW83_RS12180	COG0583	DNA-binding transcription factor activity
DIW83_RS12190	COG1595	DNA-templated transcription, initiation
DIW83_RS12200	COG3220	belongs to the UPF0276 family
DIW83_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS12230	COG2076	Multidrug Resistance protein
DIW83_RS12245	COG3713	MltA-interacting MipA family protein
DIW83_RS12250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIW83_RS12340	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIW83_RS12350	COG0789	Transcriptional regulator
DIW83_RS12355	COG1278	Cold shock
DIW83_RS12370	COG2801	Transposase and inactivated derivatives
DIW83_RS12385	COG1522	sequence-specific DNA binding
DIW83_RS12400	COG4774	siderophore transport
DIW83_RS12420	COG2814	Major facilitator Superfamily
DIW83_RS12460	COG0583	DNA-binding transcription factor activity
DIW83_RS12465	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS12475	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS12480	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS12485	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS12500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DIW83_RS12510	COG4122	O-methyltransferase activity
DIW83_RS12540	COG1538	Outer membrane efflux protein
DIW83_RS12550	COG1137	ATPase activity
DIW83_RS12555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DIW83_RS12565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DIW83_RS12570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DIW83_RS12570	COG0517	IMP dehydrogenase activity
DIW83_RS12645	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS12675	COG1570	exodeoxyribonuclease VII activity
DIW83_RS12710	COG3791	Glutathione-dependent formaldehyde-activating
DIW83_RS12730	COG0583	DNA-binding transcription factor activity
DIW83_RS12740	COG4638	Rieske (2fe-2S)
DIW83_RS12745	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DIW83_RS12750	COG0633	Ferredoxin
DIW83_RS12750	COG0543	2 iron, 2 sulfur cluster binding
DIW83_RS12755	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS12760	COG3135	benzoate transporter
DIW83_RS12765	COG2814	Major facilitator Superfamily
DIW83_RS12780	COG1643	Atp-dependent helicase
DIW83_RS12785	COG0450	alkyl hydroperoxide reductase
DIW83_RS12805	COG3634	alkyl hydroperoxide reductase activity
DIW83_RS12825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DIW83_RS12830	COG0582	viral genome integration into host DNA
DIW83_RS12860	COG2814	Major facilitator Superfamily
DIW83_RS12985	COG0625	glutathione transferase activity
DIW83_RS12995	COG2885	chlorophyll binding
DIW83_RS13030	COG0542	response to heat
DIW83_RS13045	COG1765	OsmC-like protein
DIW83_RS13055	COG0667	Aldo Keto reductase
DIW83_RS13070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DIW83_RS13090	COG0527	aspartate kinase activity
DIW83_RS13100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIW83_RS13110	COG3038	cytochrome b561
DIW83_RS13120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIW83_RS13125	COG2252	PERMEase
DIW83_RS13135	COG2072	flavoprotein involved in K transport
DIW83_RS13140	COG0300	oxidoreductase activity
DIW83_RS13150	COG1741	Belongs to the pirin family
DIW83_RS13155	COG1309	transcriptional regulator
DIW83_RS13170	COG2072	flavoprotein involved in K transport
DIW83_RS13175	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DIW83_RS13205	COG1944	ATP diphosphatase activity
DIW83_RS13225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIW83_RS13245	COG1024	Enoyl-CoA hydratase
DIW83_RS13250	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS13260	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS13285	COG0697	spore germination
DIW83_RS13300	COG1113	amino acid transport
DIW83_RS13320	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS13340	COG0531	amino acid
DIW83_RS13350	COG1113	amino acid transport
DIW83_RS13415	COG3209	COG3209 Rhs family protein
DIW83_RS13475	COG0446	pyridine nucleotide-disulphide oxidoreductase
DIW83_RS13475	COG1902	pentaerythritol trinitrate reductase activity
DIW83_RS13490	COG5001	Diguanylate cyclase
DIW83_RS13490	COG2203	Gaf domain
DIW83_RS13490	COG3706	GGDEF domain
DIW83_RS13490	COG4251	negative regulation of phosphorylation
DIW83_RS13500	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DIW83_RS13525	COG4172	Belongs to the ABC transporter superfamily
DIW83_RS13530	COG4239	(ABC) transporter, permease
DIW83_RS13535	COG4174	ABC transporter (Permease)
DIW83_RS13545	COG0741	lytic transglycosylase activity
DIW83_RS13545	COG0741	lytic transglycosylase activity
DIW83_RS13545	COG1388	LysM domain
DIW83_RS13545	COG1388	LysM domain
DIW83_RS13585	COG0583	DNA-binding transcription factor activity
DIW83_RS13590	COG1279	arginine transmembrane transporter activity
DIW83_RS13610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIW83_RS13615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIW83_RS13620	COG0006	proline dipeptidase activity
DIW83_RS13655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DIW83_RS13700	COG3384	dioxygenase
DIW83_RS13710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIW83_RS13715	COG2878	Part of a membrane complex involved in electron transport
DIW83_RS13720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DIW83_RS13745	COG0768	penicillin binding
DIW83_RS13750	COG0742	ribosomal rna small subunit methyltransferase
DIW83_RS13770	COG0830	nickel cation binding
DIW83_RS13780	COG0804	urea catabolic process
DIW83_RS13825	COG1253	flavin adenine dinucleotide binding
DIW83_RS13830	COG2851	Citrate transporter
DIW83_RS13880	COG1773	rubredoxin
DIW83_RS13885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIW83_RS13895	COG0583	DNA-binding transcription factor activity
DIW83_RS13920	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DIW83_RS13925	COG4181	ATPase activity
DIW83_RS13970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIW83_RS13990	COG0306	phosphate transporter
DIW83_RS14030	COG2223	nitrite transmembrane transporter activity
DIW83_RS14035	COG2207	Transcriptional regulator
DIW83_RS14035	COG0662	Cupin 2, conserved barrel domain protein
DIW83_RS14040	COG2066	Belongs to the glutaminase family
DIW83_RS14045	COG0242	peptide deformylase activity
DIW83_RS14050	COG0477	Major facilitator Superfamily
DIW83_RS14060	COG0028	Belongs to the TPP enzyme family
DIW83_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS14080	COG2267	carboxylic ester hydrolase activity
DIW83_RS14090	COG2271	Major facilitator Superfamily
DIW83_RS14095	COG0446	pyridine nucleotide-disulphide oxidoreductase
DIW83_RS14105	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS14125	COG1414	Transcriptional regulator
DIW83_RS14150	COG1024	Enoyl-CoA hydratase
DIW83_RS14160	COG1215	transferase activity, transferring glycosyl groups
DIW83_RS14165	COG1649	PFAM Uncharacterised BCR, COG1649
DIW83_RS14165	COG0726	polysaccharide deacetylase
DIW83_RS14175	COG4681	YaeQ
DIW83_RS14185	COG0523	cobalamin synthesis protein
DIW83_RS14195	COG1607	acyl-coa hydrolase
DIW83_RS14205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DIW83_RS14210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DIW83_RS14215	COG1309	transcriptional regulator
DIW83_RS14240	COG2040	homocysteine
DIW83_RS14245	COG0531	amino acid
DIW83_RS14265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIW83_RS14270	COG0477	Major facilitator Superfamily
DIW83_RS14330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DIW83_RS14400	COG0405	Gamma-glutamyltransferase
DIW83_RS14405	COG2814	Major facilitator Superfamily
DIW83_RS14415	COG2050	protein possibly involved in aromatic compounds catabolism
DIW83_RS14430	COG1090	epimerase
DIW83_RS14450	COG0420	3'-5' exonuclease activity
DIW83_RS14460	COG1968	undecaprenyl-diphosphatase activity
DIW83_RS14480	COG0735	belongs to the Fur family
DIW83_RS14485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIW83_RS14510	COG0121	glutamine amidotransferase
DIW83_RS14525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIW83_RS14535	COG0210	DNA helicase
DIW83_RS14540	COG2885	chlorophyll binding
DIW83_RS14545	COG0204	Acyl-transferase
DIW83_RS14560	COG2894	cell division
DIW83_RS14580	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS14585	COG1674	ftsk spoiiie
DIW83_RS14590	COG0492	ferredoxin-NADP+ reductase activity
DIW83_RS14595	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DIW83_RS14605	COG0456	acetyltransferase
DIW83_RS14635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DIW83_RS14650	COG1981	membrane
DIW83_RS14665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIW83_RS14665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DIW83_RS14685	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS14690	COG4638	Rieske (2fe-2S)
DIW83_RS14695	COG0657	acetylesterase activity
DIW83_RS14705	COG0473	3-isopropylmalate dehydrogenase activity
DIW83_RS14710	COG0583	DNA-binding transcription factor activity
DIW83_RS14730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DIW83_RS14740	COG0582	viral genome integration into host DNA
DIW83_RS14910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DIW83_RS15005	COG0358	DNA primase activity
DIW83_RS15020	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DIW83_RS15050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIW83_RS15080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIW83_RS15090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DIW83_RS15090	COG0352	thiamine-phosphate diphosphorylase activity
DIW83_RS15090	COG0351	phosphomethylpyrimidine kinase
DIW83_RS15095	COG1652	LysM domain
DIW83_RS15120	COG1399	metal-binding, possibly nucleic acid-binding protein
DIW83_RS15125	COG3101	peptidyl-lysine hydroxylation
DIW83_RS15130	COG0009	L-threonylcarbamoyladenylate synthase
DIW83_RS15135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DIW83_RS15140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DIW83_RS15160	COG4106	trans-aconitate 2-methyltransferase activity
DIW83_RS15175	COG2226	methyltransferase
DIW83_RS15175	COG0596	Alpha beta hydrolase
DIW83_RS15175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIW83_RS15180	COG1877	trehalose-phosphatase activity
DIW83_RS15185	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DIW83_RS15190	COG2223	nitrite transmembrane transporter activity
DIW83_RS15210	COG1196	nuclear chromosome segregation
DIW83_RS15220	COG0730	response to heat
DIW83_RS15235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DIW83_RS15300	COG0489	protein tyrosine kinase activity
DIW83_RS15315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIW83_RS15315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIW83_RS15350	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DIW83_RS15355	COG2081	HI0933 family
DIW83_RS15365	COG0668	transmembrane transport
DIW83_RS15385	COG0583	DNA-binding transcription factor activity
DIW83_RS15410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIW83_RS15415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIW83_RS15445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DIW83_RS15470	COG3706	GGDEF domain
DIW83_RS15485	COG0745	RESPONSE REGULATOR receiver
DIW83_RS15505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIW83_RS15565	COG0384	phenazine biosynthesis protein PhzF
DIW83_RS15580	COG1309	transcriptional regulator
DIW83_RS15595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIW83_RS15610	COG0583	DNA-binding transcription factor activity
DIW83_RS15645	COG0583	DNA-binding transcription factor activity
DIW83_RS15665	COG0583	DNA-binding transcription factor activity
DIW83_RS15670	COG1053	succinate dehydrogenase
DIW83_RS15685	COG1309	transcriptional regulator
DIW83_RS15690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DIW83_RS15695	COG2814	Major facilitator Superfamily
DIW83_RS15700	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS15705	COG0583	DNA-binding transcription factor activity
DIW83_RS15710	COG1063	alcohol dehydrogenase
DIW83_RS15740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DIW83_RS15745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DIW83_RS15750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIW83_RS15770	COG2132	Multicopper oxidase
DIW83_RS15780	COG0561	phosphatase activity
DIW83_RS15785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DIW83_RS15810	COG1214	PFAM Peptidase M22, glycoprotease
DIW83_RS15850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIW83_RS15860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DIW83_RS15865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DIW83_RS15870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIW83_RS15930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIW83_RS15940	COG1846	Transcriptional regulator
DIW83_RS15945	COG1764	response to oxidative stress
DIW83_RS15970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIW83_RS15970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIW83_RS15985	COG0037	tRNA processing
DIW83_RS15995	COG0248	Ppx GppA phosphatase
DIW83_RS16025	COG0072	phenylalanine-tRNA ligase activity
DIW83_RS16055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DIW83_RS16065	COG1238	metal cluster binding
DIW83_RS16070	COG0625	glutathione transferase activity
DIW83_RS16085	COG0318	PFAM AMP-dependent synthetase and ligase
DIW83_RS16090	COG3028	Belongs to the UPF0307 family
DIW83_RS16095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIW83_RS16115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DIW83_RS16120	COG0617	tRNA 3'-terminal CCA addition
DIW83_RS16125	COG1555	photosystem II stabilization
DIW83_RS16130	COG3956	TIGRFAM MazG family protein
DIW83_RS16140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIW83_RS16160	COG0784	Response regulator, receiver
DIW83_RS16160	COG5002	protein histidine kinase activity
DIW83_RS16160	COG2205	protein histidine kinase activity
DIW83_RS16165	COG1024	Enoyl-CoA hydratase
DIW83_RS16170	COG2084	Dehydrogenase
DIW83_RS16175	COG3622	Belongs to the hyi family
DIW83_RS16205	COG0697	spore germination
DIW83_RS16215	COG2814	Major facilitator Superfamily
DIW83_RS16240	COG2072	flavoprotein involved in K transport
DIW83_RS16245	COG0492	ferredoxin-NADP+ reductase activity
DIW83_RS16250	COG0431	NADPH-dependent FMN reductase
DIW83_RS16255	COG0798	PFAM Bile acid sodium symporter
DIW83_RS16265	COG0640	Transcriptional regulator
DIW83_RS16300	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIW83_RS16325	COG2132	Multicopper oxidase
DIW83_RS16340	COG2205	protein histidine kinase activity
DIW83_RS16420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DIW83_RS16440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DIW83_RS16450	COG0084	hydrolase, TatD family'
DIW83_RS16465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DIW83_RS16520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DIW83_RS16530	COG1061	Type III restriction enzyme res subunit
DIW83_RS16535	COG1002	Type II restriction enzyme, methylase subunits
DIW83_RS16540	COG0084	hydrolase, TatD family'
DIW83_RS16660	COG0440	acetolactate synthase activity
DIW83_RS16665	COG0028	Belongs to the TPP enzyme family
DIW83_RS16690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIW83_RS16695	COG1136	(ABC) transporter
DIW83_RS16695	COG0577	efflux transmembrane transporter activity
DIW83_RS16700	COG1538	Outer membrane efflux protein
DIW83_RS16715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DIW83_RS16720	COG1162	GTPase activity
DIW83_RS16730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DIW83_RS16750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIW83_RS16770	COG1426	Protein conserved in bacteria
DIW83_RS16805	COG0793	Belongs to the peptidase S41A family
DIW83_RS16830	COG1012	belongs to the aldehyde dehydrogenase family
DIW83_RS16835	COG3265	gluconokinase activity
DIW83_RS16845	COG0800	Aldolase
DIW83_RS16855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIW83_RS16860	COG0280	phosphate acetyltransferase
DIW83_RS16860	COG0857	belongs to the CobB CobQ family
DIW83_RS16865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DIW83_RS16865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DIW83_RS16885	COG0740	serine-type endopeptidase activity
DIW83_RS16895	COG4774	siderophore transport
DIW83_RS16905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIW83_RS16915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIW83_RS16915	COG2813	Specifically methylates the guanine in position
DIW83_RS16950	COG3328	transposase activity
DIW83_RS17025	COG0788	formyltetrahydrofolate deformylase activity
DIW83_RS17050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DIW83_RS17050	COG4651	solute:proton antiporter activity
DIW83_RS17070	COG0724	RNA recognition motif
DIW83_RS17075	COG0210	DNA helicase
DIW83_RS17100	COG1733	regulation of RNA biosynthetic process
DIW83_RS17110	COG2900	Belongs to the SlyX family
DIW83_RS17115	COG0488	(ABC) transporter
DIW83_RS17125	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS17130	COG1560	Kdo2-lipid A biosynthetic process
DIW83_RS17140	COG1301	dicarboxylic acid transport
DIW83_RS17195	COG0473	3-isopropylmalate dehydrogenase activity
DIW83_RS17220	COG0583	DNA-binding transcription factor activity
DIW83_RS17265	COG0583	DNA-binding transcription factor activity
DIW83_RS17275	COG0625	glutathione transferase activity
DIW83_RS17280	COG2378	regulation of single-species biofilm formation
DIW83_RS17300	COG1530	ribonuclease E activity
DIW83_RS17305	COG0318	PFAM AMP-dependent synthetase and ligase
DIW83_RS17330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DIW83_RS17340	COG0534	Mate efflux family protein
DIW83_RS17355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DIW83_RS17385	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DIW83_RS17385	COG0493	'glutamate synthase
DIW83_RS17395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DIW83_RS17400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIW83_RS17415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DIW83_RS17425	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DIW83_RS17425	COG0644	oxidoreductase
DIW83_RS17440	COG4535	Mg2 and Co2 transporter CorC
DIW83_RS17450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIW83_RS17475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIW83_RS17480	COG0475	glutathione-regulated potassium exporter activity
DIW83_RS17480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DIW83_RS17485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DIW83_RS17495	COG0484	heat shock protein binding
DIW83_RS17500	COG0789	Transcriptional regulator
DIW83_RS17505	COG0598	Magnesium transport protein CorA
DIW83_RS17510	COG1185	polyribonucleotide nucleotidyltransferase activity
DIW83_RS17520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIW83_RS17525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIW83_RS17530	COG1074	ATP-dependent DNA helicase activity
DIW83_RS17535	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DIW83_RS17560	COG2226	methyltransferase
DIW83_RS17570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DIW83_RS17585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DIW83_RS17600	COG2111	Na H antiporter
DIW83_RS17600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIW83_RS17605	COG1006	Multisubunit Na H antiporter MnhC subunit
DIW83_RS17610	COG0651	ATP synthesis coupled electron transport
DIW83_RS17615	COG1863	multisubunit Na H antiporter MnhE subunit
DIW83_RS17620	COG2212	antiporter activity
DIW83_RS17625	COG1320	monovalent cation:proton antiporter activity
DIW83_RS17630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DIW83_RS17640	COG0195	Participates in both transcription termination and antitermination
DIW83_RS17690	COG0237	dephospho-CoA kinase activity
DIW83_RS17700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIW83_RS17715	COG0497	DNA recombination
DIW83_RS17725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DIW83_RS17740	COG1289	transmembrane transporter activity
DIW83_RS17755	COG2169	Transcriptional regulator
DIW83_RS17755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIW83_RS17760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DIW83_RS17820	COG3545	Serine hydrolase
DIW83_RS17835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DIW83_RS17850	COG0326	Molecular chaperone. Has ATPase activity
DIW83_RS17865	COG2056	Na+-H+ antiporter family
DIW83_RS17870	COG0596	Alpha beta hydrolase
DIW83_RS17970	COG0546	phosphoglycolate phosphatase activity
DIW83_RS17975	COG1716	ATPase activity
DIW83_RS18025	COG0181	hydroxymethylbilane synthase activity
DIW83_RS18035	COG3275	phosphorelay sensor kinase activity
DIW83_RS18055	COG1538	Outer membrane efflux protein
DIW83_RS18060	COG0697	spore germination
DIW83_RS18080	COG0494	nUDIX hydrolase
DIW83_RS18085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DIW83_RS18090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DIW83_RS18095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIW83_RS18100	COG0772	Belongs to the SEDS family
DIW83_RS18125	COG4974	Belongs to the 'phage' integrase family
DIW83_RS18130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DIW83_RS18140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DIW83_RS18150	COG2197	response regulator
DIW83_RS18165	COG0793	Belongs to the peptidase S41A family
DIW83_RS18170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DIW83_RS18175	COG0795	lipopolysaccharide-transporting ATPase activity
DIW83_RS18215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DIW83_RS18215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DIW83_RS18225	COG0004	ammonium transporteR
DIW83_RS18230	COG0347	Belongs to the P(II) protein family
DIW83_RS18240	COG0606	chelatase, subunit chli
DIW83_RS18250	COG0659	secondary active sulfate transmembrane transporter activity
DIW83_RS18255	COG0589	response to stress
DIW83_RS18295	COG0606	chelatase, subunit chli
DIW83_RS18300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIW83_RS18305	COG0235	Class ii aldolase
DIW83_RS18310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIW83_RS18325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DIW83_RS18340	COG0318	PFAM AMP-dependent synthetase and ligase
DIW83_RS18350	COG0477	Major facilitator Superfamily
DIW83_RS18355	COG2860	membrane
DIW83_RS18365	COG1253	flavin adenine dinucleotide binding
DIW83_RS18375	COG0477	Major facilitator Superfamily
DIW83_RS18385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIW83_RS18420	COG0655	NAD(P)H dehydrogenase (quinone) activity
DIW83_RS18435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DIW83_RS18470	COG1309	transcriptional regulator
DIW83_RS18505	COG0758	DNA mediated transformation
DIW83_RS18515	COG0697	spore germination
DIW83_RS18520	COG1309	transcriptional regulator
DIW83_RS18535	COG0386	Belongs to the glutathione peroxidase family
DIW83_RS18545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DIW83_RS18600	COG1121	(ABC) transporter
DIW83_RS18605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIW83_RS18610	COG1280	lysine exporter protein (LysE YggA)
DIW83_RS18615	COG2837	iron assimilation
DIW83_RS18620	COG0281	malic enzyme
DIW83_RS18660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIW83_RS18665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DIW83_RS18665	COG0519	Catalyzes the synthesis of GMP from XMP
DIW83_RS18670	COG4399	Belongs to the UPF0754 family
DIW83_RS18675	COG2259	Doxx family
DIW83_RS18680	COG0586	Pfam SNARE associated Golgi protein
DIW83_RS18695	COG1192	Involved in chromosome partitioning
DIW83_RS18705	COG0271	Belongs to the BolA IbaG family
DIW83_RS18750	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS18755	COG0318	PFAM AMP-dependent synthetase and ligase
DIW83_RS18760	COG2197	response regulator
DIW83_RS18770	COG3916	Acyl-homoserine-lactone synthase
DIW83_RS18775	COG0477	Major facilitator Superfamily
DIW83_RS18780	COG1024	Enoyl-CoA hydratase
DIW83_RS18785	COG1024	Enoyl-CoA hydratase
DIW83_RS18790	COG1960	acyl-CoA dehydrogenase activity
DIW83_RS18795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIW83_RS18815	COG1113	amino acid transport
DIW83_RS18820	COG1113	amino acid transport
DIW83_RS18825	COG0251	oxidation-reduction process
DIW83_RS18865	COG0564	pseudouridine synthase activity
DIW83_RS18920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DIW83_RS18935	COG1802	Transcriptional regulator
DIW83_RS18945	COG1448	Aminotransferase
DIW83_RS18950	COG0277	FAD linked oxidase domain protein
DIW83_RS18960	COG2186	Transcriptional regulator
DIW83_RS18970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIW83_RS18980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIW83_RS18995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DIW83_RS19000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIW83_RS19010	COG0438	transferase activity, transferring glycosyl groups
DIW83_RS19020	COG0438	transferase activity, transferring glycosyl groups
DIW83_RS19025	COG0463	Glycosyl transferase, family 2
DIW83_RS19025	COG1216	Glycosyl transferase, family 2
DIW83_RS19045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DIW83_RS19055	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DIW83_RS19060	COG1596	polysaccharide export
DIW83_RS19085	COG0728	peptidoglycan biosynthetic process
DIW83_RS19090	COG3023	N-Acetylmuramoyl-L-alanine amidase
DIW83_RS19150	COG0546	phosphoglycolate phosphatase activity
DIW83_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
DIW83_RS19170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DIW83_RS19170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DIW83_RS19175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DIW83_RS19180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DIW83_RS19185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIW83_RS19190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIW83_RS19195	COG1116	anion transmembrane transporter activity
DIW83_RS19200	COG1309	transcriptional regulator
DIW83_RS19205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DIW83_RS19215	COG0196	riboflavin kinase activity
DIW83_RS19220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DIW83_RS19230	COG1047	Peptidyl-prolyl cis-trans
DIW83_RS19270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DIW83_RS19275	COG0657	acetylesterase activity
DIW83_RS19325	COG2951	lytic endotransglycosylase activity
DIW83_RS19330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DIW83_RS19350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DIW83_RS19360	COG0671	phosphoesterase, PA-phosphatase related
DIW83_RS19365	COG0861	Integral membrane protein TerC family
DIW83_RS19375	COG0754	glutathionylspermidine amidase activity
DIW83_RS19385	COG0402	S-adenosylhomocysteine deaminase activity
DIW83_RS19400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DIW83_RS19405	COG1230	cation diffusion facilitator family transporter
DIW83_RS19420	COG0706	membrane insertase activity