locus-tag	class	description
CCK83_RS00005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCK83_RS00015	COG0494	nUDIX hydrolase
CCK83_RS00025	COG0642	Histidine kinase
CCK83_RS00035	COG3111	PFAM Bacterial OB fold (BOF) protein
CCK83_RS00040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCK83_RS00050	COG1720	tRNA m6t6A37 methyltransferase activity
CCK83_RS00060	COG0384	phenazine biosynthesis protein PhzF
CCK83_RS00065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCK83_RS00070	COG0826	peptidase U32
CCK83_RS00075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCK83_RS00085	COG4598	ABC transporter
CCK83_RS00090	COG4160	amino acid transport
CCK83_RS00095	COG4215	(ABC) transporter
CCK83_RS00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCK83_RS00150	COG1131	(ABC) transporter
CCK83_RS00155	COG0842	Transport permease protein
CCK83_RS00170	COG0772	Belongs to the SEDS family
CCK83_RS00175	COG2951	lytic endotransglycosylase activity
CCK83_RS00200	COG2207	Transcriptional regulator
CCK83_RS00215	COG0052	Belongs to the universal ribosomal protein uS2 family
CCK83_RS00220	COG0024	Methionine aminopeptidase
CCK83_RS00230	COG2223	nitrite transmembrane transporter activity
CCK83_RS00240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCK83_RS00245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCK83_RS00250	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS00265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CCK83_RS00270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCK83_RS00275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCK83_RS00295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCK83_RS00300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCK83_RS00305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCK83_RS00340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCK83_RS00350	COG0174	glutamine synthetase
CCK83_RS00365	COG0582	viral genome integration into host DNA
CCK83_RS00455	COG0741	lytic transglycosylase activity
CCK83_RS00455	COG0739	heme binding
CCK83_RS00455	COG1196	nuclear chromosome segregation
CCK83_RS00465	COG1598	PFAM Uncharacterised protein family UPF0150
CCK83_RS00725	COG0512	Glutamine amidotransferase of anthranilate synthase
CCK83_RS00750	COG2840	Smr protein MutS2
CCK83_RS00760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CCK83_RS00770	COG0302	gtp cyclohydrolase
CCK83_RS00790	COG3739	integral membrane protein
CCK83_RS00810	COG1169	isochorismate synthase
CCK83_RS00815	COG2977	Belongs to the P-Pant transferase superfamily
CCK83_RS00820	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CCK83_RS00825	COG1132	(ABC) transporter
CCK83_RS00830	COG1132	(ABC) transporter
CCK83_RS00845	COG3433	isochorismatase activity
CCK83_RS00845	COG1535	isochorismatase
CCK83_RS00850	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCK83_RS00855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCK83_RS00865	COG4774	siderophore transport
CCK83_RS00870	COG4607	ABC-type enterochelin transport system periplasmic component
CCK83_RS00875	COG4604	ABC transporter, ATP-binding protein
CCK83_RS00880	COG4605	iron ion homeostasis
CCK83_RS00885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCK83_RS00890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCK83_RS00905	COG1741	Belongs to the pirin family
CCK83_RS00915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCK83_RS00950	COG4829	muconolactone delta-isomerase
CCK83_RS00955	COG0183	Belongs to the thiolase family
CCK83_RS00960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCK83_RS00965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CCK83_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS01000	COG1301	dicarboxylic acid transport
CCK83_RS01030	COG2879	small protein
CCK83_RS01035	COG1966	Carbon starvation protein
CCK83_RS01040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCK83_RS01075	COG2211	Major facilitator Superfamily
CCK83_RS01080	COG1067	ATP-dependent peptidase activity
CCK83_RS01085	COG0583	DNA-binding transcription factor activity
CCK83_RS01110	COG1686	Belongs to the peptidase S11 family
CCK83_RS01115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CCK83_RS01155	COG0616	signal peptide processing
CCK83_RS01160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCK83_RS01170	COG0573	inorganic phosphate transmembrane transporter activity
CCK83_RS01175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCK83_RS01180	COG1113	amino acid transport
CCK83_RS01185	COG3961	Belongs to the TPP enzyme family
CCK83_RS01190	COG1522	sequence-specific DNA binding
CCK83_RS01200	COG0076	glutamate decarboxylase activity
CCK83_RS01205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCK83_RS01220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCK83_RS01255	COG0352	thiamine-phosphate diphosphorylase activity
CCK83_RS01280	COG0612	Peptidase, M16
CCK83_RS01290	COG1823	symporter activity
CCK83_RS01295	COG0583	DNA-binding transcription factor activity
CCK83_RS01300	COG0477	Major facilitator Superfamily
CCK83_RS01315	COG1187	pseudouridine synthase activity
CCK83_RS01330	COG1686	Belongs to the peptidase S11 family
CCK83_RS01335	COG1252	NADH dehydrogenase
CCK83_RS01345	COG0415	Belongs to the DNA photolyase family
CCK83_RS01360	COG1215	transferase activity, transferring glycosyl groups
CCK83_RS01375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCK83_RS01390	COG2070	2-Nitropropane dioxygenase
CCK83_RS01435	COG2962	Rard protein
CCK83_RS01445	COG0556	nucleotide-excision repair
CCK83_RS01465	COG0436	Aminotransferase
CCK83_RS01495	COG4221	oxidoreductase activity
CCK83_RS01505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CCK83_RS01520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCK83_RS01525	COG0571	ribonuclease III activity
CCK83_RS01535	COG0681	Belongs to the peptidase S26 family
CCK83_RS01540	COG0481	GTPase activity
CCK83_RS01545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCK83_RS01555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCK83_RS01575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCK83_RS01580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCK83_RS01585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CCK83_RS01595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CCK83_RS01600	COG4208	sulfate ABC transporter
CCK83_RS01605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCK83_RS01610	COG0583	DNA-binding transcription factor activity
CCK83_RS01615	COG4625	pathogenesis
CCK83_RS01630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CCK83_RS01645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCK83_RS01660	COG1051	belongs to the nudix hydrolase family
CCK83_RS01660	COG1056	cytidyltransferase-related domain
CCK83_RS01665	COG1024	Enoyl-CoA hydratase
CCK83_RS01675	COG2814	Major facilitator Superfamily
CCK83_RS01680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCK83_RS01680	COG0047	phosphoribosylformylglycinamidine synthase activity
CCK83_RS01700	COG1473	amidohydrolase
CCK83_RS01705	COG0824	Thioesterase
CCK83_RS01725	COG0823	Involved in the tonB-independent uptake of proteins
CCK83_RS01745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCK83_RS01785	COG0628	permease
CCK83_RS01795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCK83_RS01800	COG0596	Alpha beta hydrolase
CCK83_RS01805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCK83_RS01805	COG0616	signal peptide processing
CCK83_RS01815	COG2333	competence protein COMEC
CCK83_RS01815	COG0658	competence protein
CCK83_RS01820	COG1136	(ABC) transporter
CCK83_RS01825	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCK83_RS01855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCK83_RS01885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCK83_RS01890	COG1280	lysine exporter protein (LysE YggA)
CCK83_RS01905	COG0019	diaminopimelate decarboxylase activity
CCK83_RS01915	COG1113	amino acid transport
CCK83_RS01920	COG1115	amino acid carrier protein
CCK83_RS01950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CCK83_RS01955	COG0243	molybdopterin cofactor binding
CCK83_RS01960	COG1929	Belongs to the glycerate kinase type-1 family
CCK83_RS01975	COG0778	Nitroreductase
CCK83_RS02015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCK83_RS02040	COG0741	lytic transglycosylase activity
CCK83_RS02060	COG0584	glycerophosphoryl diester phosphodiesterase
CCK83_RS02090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCK83_RS02095	COG1597	lipid kinase activity
CCK83_RS02110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCK83_RS02115	COG0477	Major facilitator Superfamily
CCK83_RS02165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCK83_RS02170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCK83_RS02205	COG0505	Belongs to the CarA family
CCK83_RS02225	COG0251	oxidation-reduction process
CCK83_RS02235	COG0589	response to stress
CCK83_RS02255	COG2843	Capsule synthesis protein
CCK83_RS02275	COG2321	neutral zinc metallopeptidase
CCK83_RS02280	COG2354	Protein conserved in bacteria
CCK83_RS02300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCK83_RS02325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCK83_RS02330	COG1053	succinate dehydrogenase
CCK83_RS02335	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CCK83_RS02340	COG2009	succinate dehydrogenase
CCK83_RS02385	COG2921	Belongs to the UPF0250 family
CCK83_RS02390	COG0321	lipoyl(octanoyl) transferase activity
CCK83_RS02405	COG0531	amino acid
CCK83_RS02450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CCK83_RS02455	COG1648	precorrin-2 dehydrogenase activity
CCK83_RS02455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCK83_RS02470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CCK83_RS02495	COG0671	phosphoesterase, PA-phosphatase related
CCK83_RS02500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCK83_RS02510	COG1538	Outer membrane efflux protein
CCK83_RS02515	COG0393	Putative heavy-metal-binding
CCK83_RS02520	COG0393	Putative heavy-metal-binding
CCK83_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS02540	COG0525	valine-tRNA ligase activity
CCK83_RS02560	COG0583	DNA-binding transcription factor activity
CCK83_RS02565	COG0004	ammonium transporteR
CCK83_RS02575	COG0642	Histidine kinase
CCK83_RS02580	COG0745	RESPONSE REGULATOR receiver
CCK83_RS02590	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS02620	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCK83_RS02635	COG2315	Protein conserved in bacteria
CCK83_RS02640	COG0142	geranyltranstransferase activity
CCK83_RS02650	COG1113	amino acid transport
CCK83_RS02655	COG2816	NAD+ diphosphatase activity
CCK83_RS02660	COG3046	protein related to deoxyribodipyrimidine photolyase
CCK83_RS02690	COG2207	Transcriptional regulator
CCK83_RS02715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCK83_RS02735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCK83_RS02745	COG1530	ribonuclease E activity
CCK83_RS02750	COG0424	maF-like protein
CCK83_RS02755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CCK83_RS02760	COG1792	Involved in formation and maintenance of cell shape
CCK83_RS02765	COG1077	Cell shape determining protein MreB Mrl
CCK83_RS02770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCK83_RS02780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCK83_RS02815	COG3590	peptidase
CCK83_RS02820	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CCK83_RS02825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCK83_RS02830	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCK83_RS02835	COG1115	amino acid carrier protein
CCK83_RS02860	COG2814	Major facilitator Superfamily
CCK83_RS02865	COG1289	transmembrane transporter activity
CCK83_RS02875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CCK83_RS02915	COG1376	ErfK ybiS ycfS ynhG family protein
CCK83_RS02920	COG2832	Protein of unknown function (DUF454)
CCK83_RS02930	COG5510	response to toxic substance
CCK83_RS02960	COG0840	transmembrane signaling receptor activity
CCK83_RS03000	COG3422	double-strand break repair
CCK83_RS03005	COG2824	Alkylphosphonate utilization operon protein PhnA
CCK83_RS03010	COG3189	MarR family transcriptional regulator
CCK83_RS03015	COG0596	Alpha beta hydrolase
CCK83_RS03025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCK83_RS03030	COG1335	isochorismatase
CCK83_RS03035	COG0251	oxidation-reduction process
CCK83_RS03040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCK83_RS03045	COG2233	PERMEase
CCK83_RS03065	COG0354	folic acid binding
CCK83_RS03070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCK83_RS03080	COG0679	Auxin Efflux Carrier
CCK83_RS03085	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS03090	COG4772	TonB-dependent receptor
CCK83_RS03095	COG2094	Belongs to the DNA glycosylase MPG family
CCK83_RS03120	COG1217	gtp-binding protein TYPA
CCK83_RS03125	COG2233	PERMEase
CCK83_RS03135	COG0833	amino acid
CCK83_RS03140	COG1690	Belongs to the RtcB family
CCK83_RS03145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CCK83_RS03145	COG2885	chlorophyll binding
CCK83_RS03155	COG0183	Belongs to the thiolase family
CCK83_RS03175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCK83_RS03195	COG2207	Transcriptional regulator
CCK83_RS03200	COG0183	Belongs to the thiolase family
CCK83_RS03220	COG2153	protein acetylation
CCK83_RS03230	COG1272	protein, Hemolysin III
CCK83_RS03235	COG0477	Major facilitator Superfamily
CCK83_RS03250	COG0450	alkyl hydroperoxide reductase
CCK83_RS03270	COG0285	dihydrofolate synthase activity
CCK83_RS03315	COG4206	TonB-dependent receptor
CCK83_RS03320	COG2096	Adenosyltransferase
CCK83_RS03340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CCK83_RS03350	COG0745	RESPONSE REGULATOR receiver
CCK83_RS03355	COG2205	protein histidine kinase activity
CCK83_RS03365	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS03370	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS03375	COG0583	DNA-binding transcription factor activity
CCK83_RS03380	COG0625	glutathione transferase activity
CCK83_RS03430	COG1216	Glycosyl transferase, family 2
CCK83_RS03445	COG0726	polysaccharide deacetylase
CCK83_RS03460	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCK83_RS03485	COG1862	Preprotein translocase
CCK83_RS03495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCK83_RS03500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCK83_RS03510	COG3781	membrane
CCK83_RS03525	COG2350	Protein conserved in bacteria
CCK83_RS03560	COG1607	acyl-coa hydrolase
CCK83_RS03565	COG2801	Transposase and inactivated derivatives
CCK83_RS03635	COG2199	diguanylate cyclase activity
CCK83_RS03640	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CCK83_RS03640	COG2885	chlorophyll binding
CCK83_RS03645	COG1408	metallophosphoesterase
CCK83_RS03650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCK83_RS03660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCK83_RS03680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCK83_RS03685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCK83_RS03690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCK83_RS03695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCK83_RS03700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCK83_RS03710	COG2969	positive regulation of protein catabolic process
CCK83_RS03745	COG1024	Enoyl-CoA hydratase
CCK83_RS03745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCK83_RS03750	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS03755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCK83_RS03770	COG1309	transcriptional regulator
CCK83_RS03775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCK83_RS03780	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS03825	COG1183	phosphatidylcholine synthase activity
CCK83_RS03830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CCK83_RS03860	COG0739	heme binding
CCK83_RS03860	COG0741	lytic transglycosylase activity
CCK83_RS03860	COG1196	nuclear chromosome segregation
CCK83_RS03870	COG1702	phosphate starvation-inducible protein PhoH
CCK83_RS03905	COG1295	ribonuclease BN
CCK83_RS03910	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCK83_RS03960	COG0557	exoribonuclease II activity
CCK83_RS03965	COG0339	signal peptide processing
CCK83_RS03970	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CCK83_RS04000	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CCK83_RS04005	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS04140	COG0088	Forms part of the polypeptide exit tunnel
CCK83_RS04145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCK83_RS04160	COG0626	cystathionine gamma-synthase activity
CCK83_RS04165	COG0433	COG0433 Predicted ATPase
CCK83_RS04170	COG1017	nitric oxide dioxygenase activity
CCK83_RS04170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCK83_RS04175	COG1959	2 iron, 2 sulfur cluster binding
CCK83_RS04190	COG1301	dicarboxylic acid transport
CCK83_RS04195	COG1946	Acyl-CoA thioesterase
CCK83_RS04215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCK83_RS04220	COG1040	competence protein
CCK83_RS04225	COG0494	nUDIX hydrolase
CCK83_RS04235	COG0598	Magnesium transport protein CorA
CCK83_RS04245	COG2854	intermembrane phospholipid transfer
CCK83_RS04255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCK83_RS04260	COG1127	ABC transporter
CCK83_RS04270	COG0513	Belongs to the DEAD box helicase family
CCK83_RS04290	COG0408	coproporphyrinogen oxidase activity
CCK83_RS04305	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS04315	COG1983	PspC domain protein
CCK83_RS04320	COG0617	tRNA 3'-terminal CCA addition
CCK83_RS04320	COG0517	IMP dehydrogenase activity
CCK83_RS04320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CCK83_RS04345	COG0752	glycyl-tRNA synthetase alpha subunit
CCK83_RS04370	COG0583	DNA-binding transcription factor activity
CCK83_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS04420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCK83_RS04425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCK83_RS04430	COG0833	amino acid
CCK83_RS04460	COG1192	Involved in chromosome partitioning
CCK83_RS04465	COG0628	permease
CCK83_RS04475	COG1289	transmembrane transporter activity
CCK83_RS04490	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCK83_RS04495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CCK83_RS04520	COG0277	FAD linked oxidase domain protein
CCK83_RS04525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCK83_RS04535	COG5006	permease, DMT superfamily
CCK83_RS04550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCK83_RS04555	COG5380	lipid catabolic process
CCK83_RS04565	COG0335	large ribosomal subunit rRNA binding
CCK83_RS04575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCK83_RS04625	COG0194	GDP metabolic process
CCK83_RS04635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCK83_RS04655	COG3307	-O-antigen
CCK83_RS04675	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CCK83_RS04680	COG1704	LemA family
CCK83_RS04690	COG0493	'glutamate synthase
CCK83_RS04695	COG0070	glutamate synthase
CCK83_RS04695	COG0067	glutamate synthase
CCK83_RS04695	COG0069	glutamate synthase activity
CCK83_RS04745	COG2226	methyltransferase
CCK83_RS04760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCK83_RS04765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCK83_RS04810	COG0833	amino acid
CCK83_RS04895	COG0488	(ABC) transporter
CCK83_RS04900	COG2873	o-acetylhomoserine
CCK83_RS04905	COG4221	oxidoreductase activity
CCK83_RS04910	COG0659	secondary active sulfate transmembrane transporter activity
CCK83_RS04935	COG0427	acetyl-CoA hydrolase
CCK83_RS04965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CCK83_RS04975	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CCK83_RS04985	COG4619	ABC transporter
CCK83_RS04995	COG0697	spore germination
CCK83_RS05000	COG2329	Antibiotic biosynthesis monooxygenase
CCK83_RS05015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCK83_RS05085	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCK83_RS05090	COG1733	regulation of RNA biosynthetic process
CCK83_RS05105	COG1309	transcriptional regulator
CCK83_RS05125	COG0667	Aldo Keto reductase
CCK83_RS05145	COG0583	DNA-binding transcription factor activity
CCK83_RS05150	COG2814	Major facilitator Superfamily
CCK83_RS05190	COG1335	isochorismatase
CCK83_RS05200	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS05205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCK83_RS05215	COG1113	amino acid transport
CCK83_RS05225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CCK83_RS05240	COG2814	Major facilitator Superfamily
CCK83_RS05250	COG0351	phosphomethylpyrimidine kinase
CCK83_RS05250	COG0352	thiamine-phosphate diphosphorylase activity
CCK83_RS05250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CCK83_RS05270	COG1309	transcriptional regulator
CCK83_RS05290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCK83_RS05300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCK83_RS05305	COG3162	membrane
CCK83_RS05310	COG2205	protein histidine kinase activity
CCK83_RS05310	COG2198	Histidine kinase
CCK83_RS05310	COG0784	Response regulator, receiver
CCK83_RS05335	COG1522	sequence-specific DNA binding
CCK83_RS05340	COG1335	isochorismatase
CCK83_RS05345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCK83_RS05355	COG0668	transmembrane transport
CCK83_RS05360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCK83_RS05365	COG1519	Transferase
CCK83_RS05370	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS05390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCK83_RS05410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCK83_RS05410	COG0426	domain, Protein
CCK83_RS05415	COG4774	siderophore transport
CCK83_RS05420	COG2119	membrane
CCK83_RS05430	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCK83_RS05440	COG4942	peptidase
CCK83_RS05455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CCK83_RS05465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCK83_RS05485	COG0189	ligase activity
CCK83_RS05515	COG0708	Exodeoxyribonuclease III
CCK83_RS05520	COG1393	Belongs to the ArsC family
CCK83_RS05535	COG3706	GGDEF domain
CCK83_RS05570	COG2351	hydroxyisourate hydrolase activity
CCK83_RS05575	COG2233	PERMEase
CCK83_RS05585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS05595	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CCK83_RS05605	COG3150	esterase
CCK83_RS05650	COG2918	glutathione biosynthetic process
CCK83_RS05665	COG2733	membrane
CCK83_RS05670	COG0436	Aminotransferase
CCK83_RS05675	COG0534	Mate efflux family protein
CCK83_RS05780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CCK83_RS05785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CCK83_RS05795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CCK83_RS05810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCK83_RS05815	COG0546	phosphoglycolate phosphatase activity
CCK83_RS05875	COG0010	Belongs to the arginase family
CCK83_RS05905	COG2188	Transcriptional regulator
CCK83_RS05915	COG0523	cobalamin synthesis protein
CCK83_RS05925	COG1113	amino acid transport
CCK83_RS05935	COG0625	glutathione transferase activity
CCK83_RS05940	COG0346	lactoylglutathione lyase activity
CCK83_RS05955	COG1683	Conserved Protein
CCK83_RS05960	COG0534	Mate efflux family protein
CCK83_RS05965	COG0385	Bile acid
CCK83_RS05970	COG1335	isochorismatase
CCK83_RS05975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCK83_RS05995	COG2116	formate transmembrane transporter activity
CCK83_RS06000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCK83_RS06005	COG2133	pyrroloquinoline quinone binding
CCK83_RS06010	COG2983	Belongs to the UPF0260 family
CCK83_RS06015	COG5487	UPF0391 membrane protein
CCK83_RS06030	COG1194	a g-specific adenine glycosylase
CCK83_RS06045	COG2818	Glycosylase
CCK83_RS06050	COG1064	alcohol dehydrogenase
CCK83_RS06055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCK83_RS06070	COG0583	DNA-binding transcription factor activity
CCK83_RS06075	COG0656	L-ascorbic acid biosynthetic process
CCK83_RS06080	COG2814	Major facilitator Superfamily
CCK83_RS06115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCK83_RS06130	COG2233	PERMEase
CCK83_RS06170	COG0733	neurotransmitter:sodium symporter activity
CCK83_RS06180	COG0625	glutathione transferase activity
CCK83_RS06210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCK83_RS06215	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CCK83_RS06220	COG0596	Alpha beta hydrolase
CCK83_RS06250	COG0488	(ABC) transporter
CCK83_RS06265	COG0187	DNA topoisomerase II activity
CCK83_RS06275	COG0592	DNA-directed DNA polymerase activity
CCK83_RS06300	COG0706	membrane insertase activity
CCK83_RS06315	COG1230	cation diffusion facilitator family transporter
CCK83_RS06320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCK83_RS06335	COG0402	S-adenosylhomocysteine deaminase activity
CCK83_RS06345	COG0754	glutathionylspermidine amidase activity
CCK83_RS06355	COG0861	Integral membrane protein TerC family
CCK83_RS06360	COG0671	phosphoesterase, PA-phosphatase related
CCK83_RS06370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCK83_RS06385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCK83_RS06390	COG2951	lytic endotransglycosylase activity
CCK83_RS06440	COG0657	acetylesterase activity
CCK83_RS06445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCK83_RS06485	COG1047	Peptidyl-prolyl cis-trans
CCK83_RS06495	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCK83_RS06500	COG0196	riboflavin kinase activity
CCK83_RS06510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCK83_RS06515	COG1309	transcriptional regulator
CCK83_RS06520	COG1116	anion transmembrane transporter activity
CCK83_RS06525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCK83_RS06530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCK83_RS06535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCK83_RS06540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCK83_RS06545	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCK83_RS06545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCK83_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS06565	COG0546	phosphoglycolate phosphatase activity
CCK83_RS06625	COG3023	N-Acetylmuramoyl-L-alanine amidase
CCK83_RS06630	COG0728	peptidoglycan biosynthetic process
CCK83_RS06660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CCK83_RS06685	COG1091	dTDP-4-dehydrorhamnose reductase activity
CCK83_RS06720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCK83_RS06725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCK83_RS06740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCK83_RS06750	COG2186	Transcriptional regulator
CCK83_RS06760	COG0277	FAD linked oxidase domain protein
CCK83_RS06765	COG1448	Aminotransferase
CCK83_RS06775	COG1802	Transcriptional regulator
CCK83_RS06790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CCK83_RS06795	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS06870	COG0564	pseudouridine synthase activity
CCK83_RS06910	COG0251	oxidation-reduction process
CCK83_RS06915	COG1113	amino acid transport
CCK83_RS06920	COG1113	amino acid transport
CCK83_RS06940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCK83_RS06945	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS06950	COG1024	Enoyl-CoA hydratase
CCK83_RS06955	COG1024	Enoyl-CoA hydratase
CCK83_RS06960	COG0477	Major facilitator Superfamily
CCK83_RS06965	COG0697	spore germination
CCK83_RS06970	COG1113	amino acid transport
CCK83_RS06975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCK83_RS06985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCK83_RS06990	COG3916	Acyl-homoserine-lactone synthase
CCK83_RS07000	COG2197	response regulator
CCK83_RS07005	COG0318	PFAM AMP-dependent synthetase and ligase
CCK83_RS07010	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS07015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCK83_RS07015	COG3321	synthase
CCK83_RS07015	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CCK83_RS07015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCK83_RS07055	COG0271	Belongs to the BolA IbaG family
CCK83_RS07065	COG1192	Involved in chromosome partitioning
CCK83_RS07080	COG0586	Pfam SNARE associated Golgi protein
CCK83_RS07085	COG2259	Doxx family
CCK83_RS07090	COG4399	Belongs to the UPF0754 family
CCK83_RS07095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCK83_RS07095	COG0519	Catalyzes the synthesis of GMP from XMP
CCK83_RS07145	COG0281	malic enzyme
CCK83_RS07150	COG2837	iron assimilation
CCK83_RS07155	COG1280	lysine exporter protein (LysE YggA)
CCK83_RS07160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCK83_RS07165	COG1121	(ABC) transporter
CCK83_RS07205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCK83_RS07215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCK83_RS07230	COG0386	Belongs to the glutathione peroxidase family
CCK83_RS07245	COG1309	transcriptional regulator
CCK83_RS07250	COG0697	spore germination
CCK83_RS07260	COG0758	DNA mediated transformation
CCK83_RS07295	COG1309	transcriptional regulator
CCK83_RS07325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCK83_RS07340	COG0655	NAD(P)H dehydrogenase (quinone) activity
CCK83_RS07380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCK83_RS07390	COG2814	Major facilitator Superfamily
CCK83_RS07400	COG1253	flavin adenine dinucleotide binding
CCK83_RS07410	COG2860	membrane
CCK83_RS07415	COG0477	Major facilitator Superfamily
CCK83_RS07425	COG0318	PFAM AMP-dependent synthetase and ligase
CCK83_RS07440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCK83_RS07460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCK83_RS07465	COG0235	Class ii aldolase
CCK83_RS07470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCK83_RS07475	COG0431	NADPH-dependent FMN reductase
CCK83_RS07480	COG0606	chelatase, subunit chli
CCK83_RS07520	COG0589	response to stress
CCK83_RS07525	COG0659	secondary active sulfate transmembrane transporter activity
CCK83_RS07535	COG0606	chelatase, subunit chli
CCK83_RS07545	COG0347	Belongs to the P(II) protein family
CCK83_RS07550	COG0004	ammonium transporteR
CCK83_RS07560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCK83_RS07560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCK83_RS07600	COG0795	lipopolysaccharide-transporting ATPase activity
CCK83_RS07605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CCK83_RS07610	COG0793	Belongs to the peptidase S41A family
CCK83_RS07625	COG2197	response regulator
CCK83_RS07635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCK83_RS07645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCK83_RS07650	COG4974	Belongs to the 'phage' integrase family
CCK83_RS07675	COG0772	Belongs to the SEDS family
CCK83_RS07680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCK83_RS07685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCK83_RS07690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCK83_RS07695	COG0494	nUDIX hydrolase
CCK83_RS07715	COG0697	spore germination
CCK83_RS07725	COG1538	Outer membrane efflux protein
CCK83_RS07745	COG3275	phosphorelay sensor kinase activity
CCK83_RS07755	COG0181	hydroxymethylbilane synthase activity
CCK83_RS07800	COG1716	ATPase activity
CCK83_RS07805	COG0546	phosphoglycolate phosphatase activity
CCK83_RS07835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCK83_RS07905	COG2056	Na+-H+ antiporter family
CCK83_RS07920	COG0326	Molecular chaperone. Has ATPase activity
CCK83_RS07935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CCK83_RS08010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCK83_RS08015	COG2169	Transcriptional regulator
CCK83_RS08015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCK83_RS08050	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCK83_RS08060	COG0497	DNA recombination
CCK83_RS08075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCK83_RS08085	COG0237	dephospho-CoA kinase activity
CCK83_RS08135	COG0195	Participates in both transcription termination and antitermination
CCK83_RS08145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCK83_RS08150	COG1320	monovalent cation:proton antiporter activity
CCK83_RS08155	COG2212	antiporter activity
CCK83_RS08160	COG1863	multisubunit Na H antiporter MnhE subunit
CCK83_RS08165	COG0651	ATP synthesis coupled electron transport
CCK83_RS08170	COG1006	Multisubunit Na H antiporter MnhC subunit
CCK83_RS08175	COG2111	Na H antiporter
CCK83_RS08175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCK83_RS08190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCK83_RS08200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS08205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCK83_RS08215	COG2226	methyltransferase
CCK83_RS08235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CCK83_RS08240	COG1074	ATP-dependent DNA helicase activity
CCK83_RS08245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCK83_RS08250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCK83_RS08260	COG1185	polyribonucleotide nucleotidyltransferase activity
CCK83_RS08265	COG0598	Magnesium transport protein CorA
CCK83_RS08270	COG0789	Transcriptional regulator
CCK83_RS08275	COG0484	heat shock protein binding
CCK83_RS08285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCK83_RS08295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCK83_RS08315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCK83_RS08325	COG4535	Mg2 and Co2 transporter CorC
CCK83_RS08340	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CCK83_RS08340	COG0644	oxidoreductase
CCK83_RS08350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCK83_RS08365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCK83_RS08370	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CCK83_RS08380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCK83_RS08380	COG0493	'glutamate synthase
CCK83_RS08405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCK83_RS08420	COG0534	Mate efflux family protein
CCK83_RS08430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCK83_RS08435	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS08440	COG0583	DNA-binding transcription factor activity
CCK83_RS08455	COG0318	PFAM AMP-dependent synthetase and ligase
CCK83_RS08460	COG1530	ribonuclease E activity
CCK83_RS08475	COG0546	phosphoglycolate phosphatase activity
CCK83_RS08480	COG2378	regulation of single-species biofilm formation
CCK83_RS08485	COG0625	glutathione transferase activity
CCK83_RS08495	COG0583	DNA-binding transcription factor activity
CCK83_RS08535	COG0583	DNA-binding transcription factor activity
CCK83_RS08560	COG0473	3-isopropylmalate dehydrogenase activity
CCK83_RS08615	COG1301	dicarboxylic acid transport
CCK83_RS08625	COG1560	Kdo2-lipid A biosynthetic process
CCK83_RS08635	COG0488	(ABC) transporter
CCK83_RS08640	COG2900	Belongs to the SlyX family
CCK83_RS08650	COG1733	regulation of RNA biosynthetic process
CCK83_RS08675	COG0210	DNA helicase
CCK83_RS08680	COG0724	RNA recognition motif
CCK83_RS08700	COG4651	solute:proton antiporter activity
CCK83_RS08700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCK83_RS08725	COG0788	formyltetrahydrofolate deformylase activity
CCK83_RS08825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCK83_RS08825	COG2813	Specifically methylates the guanine in position
CCK83_RS08835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCK83_RS08845	COG4774	siderophore transport
CCK83_RS08855	COG0740	serine-type endopeptidase activity
CCK83_RS08875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CCK83_RS08875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CCK83_RS08880	COG0857	belongs to the CobB CobQ family
CCK83_RS08880	COG0280	phosphate acetyltransferase
CCK83_RS08885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCK83_RS08900	COG0800	Aldolase
CCK83_RS08910	COG3265	gluconokinase activity
CCK83_RS08915	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS08925	COG2267	carboxylic ester hydrolase activity
CCK83_RS08940	COG0793	Belongs to the peptidase S41A family
CCK83_RS08975	COG1426	Protein conserved in bacteria
CCK83_RS08995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCK83_RS09015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCK83_RS09025	COG1162	GTPase activity
CCK83_RS09030	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CCK83_RS09050	COG0577	efflux transmembrane transporter activity
CCK83_RS09050	COG1136	(ABC) transporter
CCK83_RS09055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCK83_RS09075	COG0028	Belongs to the TPP enzyme family
CCK83_RS09080	COG0440	acetolactate synthase activity
CCK83_RS09085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCK83_RS09095	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS09105	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS09240	COG0582	viral genome integration into host DNA
CCK83_RS09250	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCK83_RS09265	COG0084	hydrolase, TatD family'
CCK83_RS09280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCK83_RS09290	COG0583	DNA-binding transcription factor activity
CCK83_RS09295	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS09300	COG0583	DNA-binding transcription factor activity
CCK83_RS09310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCK83_RS09385	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CCK83_RS09395	COG0732	type I restriction modification DNA specificity domain
CCK83_RS09415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CCK83_RS09430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCK83_RS09455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCK83_RS09460	COG0625	glutathione transferase activity
CCK83_RS09500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CCK83_RS09510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCK83_RS09530	COG2009	succinate dehydrogenase
CCK83_RS09545	COG1074	ATP-dependent DNA helicase activity
CCK83_RS09580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCK83_RS09590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCK83_RS09595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCK83_RS09600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCK83_RS09620	COG2814	Major facilitator Superfamily
CCK83_RS09630	COG0697	spore germination
CCK83_RS09660	COG3622	Belongs to the hyi family
CCK83_RS09665	COG2084	Dehydrogenase
CCK83_RS09670	COG1024	Enoyl-CoA hydratase
CCK83_RS09675	COG2205	protein histidine kinase activity
CCK83_RS09675	COG5002	protein histidine kinase activity
CCK83_RS09675	COG0784	Response regulator, receiver
CCK83_RS09695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCK83_RS09700	COG4221	oxidoreductase activity
CCK83_RS09705	COG3956	TIGRFAM MazG family protein
CCK83_RS09710	COG1555	photosystem II stabilization
CCK83_RS09715	COG0617	tRNA 3'-terminal CCA addition
CCK83_RS09720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCK83_RS09740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCK83_RS09745	COG3028	Belongs to the UPF0307 family
CCK83_RS09750	COG0318	PFAM AMP-dependent synthetase and ligase
CCK83_RS09770	COG0625	glutathione transferase activity
CCK83_RS09775	COG1238	metal cluster binding
CCK83_RS09790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCK83_RS09820	COG0072	phenylalanine-tRNA ligase activity
CCK83_RS09850	COG0248	Ppx GppA phosphatase
CCK83_RS09860	COG0037	tRNA processing
CCK83_RS09900	COG1764	response to oxidative stress
CCK83_RS09905	COG1846	Transcriptional regulator
CCK83_RS09915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCK83_RS09975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCK83_RS09980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCK83_RS09985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCK83_RS10035	COG1214	PFAM Peptidase M22, glycoprotease
CCK83_RS10060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCK83_RS10065	COG0561	phosphatase activity
CCK83_RS10075	COG2132	Multicopper oxidase
CCK83_RS10100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCK83_RS10105	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CCK83_RS10140	COG1063	alcohol dehydrogenase
CCK83_RS10145	COG0583	DNA-binding transcription factor activity
CCK83_RS10150	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS10155	COG2814	Major facilitator Superfamily
CCK83_RS10160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCK83_RS10170	COG1309	transcriptional regulator
CCK83_RS10185	COG1053	succinate dehydrogenase
CCK83_RS10190	COG0583	DNA-binding transcription factor activity
CCK83_RS10210	COG0583	DNA-binding transcription factor activity
CCK83_RS10265	COG0583	DNA-binding transcription factor activity
CCK83_RS10280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCK83_RS10305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCK83_RS10320	COG0745	RESPONSE REGULATOR receiver
CCK83_RS10335	COG2199	diguanylate cyclase activity
CCK83_RS10360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CCK83_RS10390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCK83_RS10395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCK83_RS10415	COG0583	DNA-binding transcription factor activity
CCK83_RS10435	COG0668	transmembrane transport
CCK83_RS10445	COG2081	HI0933 family
CCK83_RS10450	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CCK83_RS10485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCK83_RS10485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCK83_RS10495	COG0489	protein tyrosine kinase activity
CCK83_RS10500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCK83_RS10550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCK83_RS10560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCK83_RS10575	COG0730	response to heat
CCK83_RS10585	COG1196	nuclear chromosome segregation
CCK83_RS10605	COG2223	nitrite transmembrane transporter activity
CCK83_RS10610	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CCK83_RS10620	COG2226	methyltransferase
CCK83_RS10620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCK83_RS10620	COG0596	Alpha beta hydrolase
CCK83_RS10635	COG4106	trans-aconitate 2-methyltransferase activity
CCK83_RS10650	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCK83_RS10655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CCK83_RS10660	COG0009	L-threonylcarbamoyladenylate synthase
CCK83_RS10665	COG3101	peptidyl-lysine hydroxylation
CCK83_RS10670	COG1399	metal-binding, possibly nucleic acid-binding protein
CCK83_RS10695	COG1652	LysM domain
CCK83_RS10700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CCK83_RS10700	COG0352	thiamine-phosphate diphosphorylase activity
CCK83_RS10700	COG0351	phosphomethylpyrimidine kinase
CCK83_RS10710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCK83_RS10740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCK83_RS10770	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CCK83_RS10785	COG0358	DNA primase activity
CCK83_RS10820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCK83_RS10840	COG0583	DNA-binding transcription factor activity
CCK83_RS10845	COG0473	3-isopropylmalate dehydrogenase activity
CCK83_RS10855	COG0657	acetylesterase activity
CCK83_RS10860	COG4638	Rieske (2fe-2S)
CCK83_RS10865	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS10885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CCK83_RS10885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCK83_RS10895	COG1981	membrane
CCK83_RS10910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCK83_RS10920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCK83_RS10925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCK83_RS10940	COG0456	acetyltransferase
CCK83_RS10950	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CCK83_RS10955	COG0492	ferredoxin-NADP+ reductase activity
CCK83_RS10960	COG1674	ftsk spoiiie
CCK83_RS10965	COG1280	lysine exporter protein (LysE YggA)
CCK83_RS10970	COG4372	Transposase
CCK83_RS11000	COG2894	cell division
CCK83_RS11015	COG0204	Acyl-transferase
CCK83_RS11020	COG2885	chlorophyll binding
CCK83_RS11025	COG0210	DNA helicase
CCK83_RS11035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCK83_RS11050	COG0121	glutamine amidotransferase
CCK83_RS11060	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS11080	COG2914	Belongs to the UPF0125 (RnfH) family
CCK83_RS11085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCK83_RS11090	COG0735	belongs to the Fur family
CCK83_RS11115	COG0420	3'-5' exonuclease activity
CCK83_RS11135	COG1090	epimerase
CCK83_RS11150	COG2050	protein possibly involved in aromatic compounds catabolism
CCK83_RS11160	COG2814	Major facilitator Superfamily
CCK83_RS11165	COG0405	Gamma-glutamyltransferase
CCK83_RS11180	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS11200	COG0477	Major facilitator Superfamily
CCK83_RS11205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCK83_RS11215	COG1595	DNA-templated transcription, initiation
CCK83_RS11270	COG0531	amino acid
CCK83_RS11275	COG2040	homocysteine
CCK83_RS11300	COG1309	transcriptional regulator
CCK83_RS11305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCK83_RS11310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCK83_RS11320	COG1607	acyl-coa hydrolase
CCK83_RS11330	COG0523	cobalamin synthesis protein
CCK83_RS11340	COG4681	YaeQ
CCK83_RS11350	COG1649	PFAM Uncharacterised BCR, COG1649
CCK83_RS11350	COG0726	polysaccharide deacetylase
CCK83_RS11355	COG1215	transferase activity, transferring glycosyl groups
CCK83_RS11365	COG1024	Enoyl-CoA hydratase
CCK83_RS11380	COG1414	Transcriptional regulator
CCK83_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS11415	COG2271	Major facilitator Superfamily
CCK83_RS11425	COG2267	carboxylic ester hydrolase activity
CCK83_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS11445	COG0028	Belongs to the TPP enzyme family
CCK83_RS11460	COG0477	Major facilitator Superfamily
CCK83_RS11465	COG0242	peptide deformylase activity
CCK83_RS11470	COG2066	Belongs to the glutaminase family
CCK83_RS11475	COG2207	Transcriptional regulator
CCK83_RS11480	COG2223	nitrite transmembrane transporter activity
CCK83_RS11500	COG3958	Transketolase
CCK83_RS11510	COG0306	phosphate transporter
CCK83_RS11530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCK83_RS11575	COG4181	ATPase activity
CCK83_RS11580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CCK83_RS11610	COG0583	DNA-binding transcription factor activity
CCK83_RS11615	COG2267	carboxylic ester hydrolase activity
CCK83_RS11620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCK83_RS11625	COG1773	rubredoxin
CCK83_RS11670	COG2851	Citrate transporter
CCK83_RS11685	COG1253	flavin adenine dinucleotide binding
CCK83_RS11700	COG3015	lipoprotein NlpE involved in copper resistance
CCK83_RS11730	COG0804	urea catabolic process
CCK83_RS11740	COG0830	nickel cation binding
CCK83_RS11755	COG0742	ribosomal rna small subunit methyltransferase
CCK83_RS11760	COG0768	penicillin binding
CCK83_RS11785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCK83_RS11790	COG2878	Part of a membrane complex involved in electron transport
CCK83_RS11795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCK83_RS11805	COG3384	dioxygenase
CCK83_RS11820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCK83_RS11860	COG0006	proline dipeptidase activity
CCK83_RS11865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS11870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS11890	COG1279	arginine transmembrane transporter activity
CCK83_RS11895	COG0583	DNA-binding transcription factor activity
CCK83_RS11940	COG0741	lytic transglycosylase activity
CCK83_RS11940	COG1388	LysM domain
CCK83_RS11945	COG4166	transmembrane transport
CCK83_RS11950	COG4174	ABC transporter (Permease)
CCK83_RS11955	COG4239	(ABC) transporter, permease
CCK83_RS11960	COG4172	Belongs to the ABC transporter superfamily
CCK83_RS11985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCK83_RS11995	COG2203	Gaf domain
CCK83_RS11995	COG3706	GGDEF domain
CCK83_RS11995	COG4251	negative regulation of phosphorylation
CCK83_RS11995	COG5001	Diguanylate cyclase
CCK83_RS12005	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCK83_RS12005	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS12025	COG4269	membrane
CCK83_RS12035	COG2801	Transposase and inactivated derivatives
CCK83_RS12070	COG1113	amino acid transport
CCK83_RS12080	COG0531	amino acid
CCK83_RS12100	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS12120	COG1113	amino acid transport
CCK83_RS12140	COG0697	spore germination
CCK83_RS12145	COG2721	sulfolactate sulfo-lyase activity
CCK83_RS12150	COG2271	Major facilitator Superfamily
CCK83_RS12155	COG4948	Mandelate Racemase Muconate Lactonizing
CCK83_RS12165	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS12170	COG2186	Transcriptional regulator
CCK83_RS12195	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS12210	COG1024	Enoyl-CoA hydratase
CCK83_RS12215	COG2814	Major facilitator Superfamily
CCK83_RS12230	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS12235	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CCK83_RS12245	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS12255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCK83_RS12270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCK83_RS12290	COG1944	ATP diphosphatase activity
CCK83_RS12315	COG1309	transcriptional regulator
CCK83_RS12320	COG1741	Belongs to the pirin family
CCK83_RS12330	COG2252	PERMEase
CCK83_RS12335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCK83_RS12340	COG3038	cytochrome b561
CCK83_RS12350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCK83_RS12360	COG0527	aspartate kinase activity
CCK83_RS12555	COG1598	PFAM Uncharacterised protein family UPF0150
CCK83_RS12625	COG1063	alcohol dehydrogenase
CCK83_RS12630	COG3293	Transposase
CCK83_RS12645	COG0582	viral genome integration into host DNA
CCK83_RS12655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCK83_RS12665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCK83_RS12680	COG0667	Aldo Keto reductase
CCK83_RS12695	COG1765	OsmC-like protein
CCK83_RS12710	COG0542	response to heat
CCK83_RS12725	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS12750	COG2885	chlorophyll binding
CCK83_RS12760	COG0625	glutathione transferase activity
CCK83_RS12765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCK83_RS12775	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS12795	COG3634	alkyl hydroperoxide reductase activity
CCK83_RS12820	COG1643	Atp-dependent helicase
CCK83_RS12835	COG2814	Major facilitator Superfamily
CCK83_RS12840	COG3135	benzoate transporter
CCK83_RS12845	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS12850	COG0543	2 iron, 2 sulfur cluster binding
CCK83_RS12850	COG0633	Ferredoxin
CCK83_RS12860	COG4638	Rieske (2fe-2S)
CCK83_RS12870	COG0583	DNA-binding transcription factor activity
CCK83_RS12880	COG2871	sodium ion transport
CCK83_RS12965	COG1570	exodeoxyribonuclease VII activity
CCK83_RS13000	COG1280	lysine exporter protein (LysE YggA)
CCK83_RS13005	COG1560	Kdo2-lipid A biosynthetic process
CCK83_RS13010	COG1278	Cold shock
CCK83_RS13020	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS13040	COG1011	Hydrolase
CCK83_RS13045	COG2226	methyltransferase
CCK83_RS13060	COG1309	transcriptional regulator
CCK83_RS13075	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS13110	COG0668	transmembrane transport
CCK83_RS13120	COG2814	Major facilitator Superfamily
CCK83_RS13165	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CCK83_RS13175	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CCK83_RS13180	COG1137	ATPase activity
CCK83_RS13185	COG1538	Outer membrane efflux protein
CCK83_RS13215	COG4122	O-methyltransferase activity
CCK83_RS13225	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CCK83_RS13240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCK83_RS13255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCK83_RS13260	COG0531	amino acid
CCK83_RS13265	COG1522	sequence-specific DNA binding
CCK83_RS13285	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS13300	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS13310	COG1278	Cold shock
CCK83_RS13320	COG2207	Transcriptional regulator
CCK83_RS13335	COG0753	catalase activity
CCK83_RS13340	COG3038	cytochrome b561
CCK83_RS13395	COG1309	transcriptional regulator
CCK83_RS13410	COG0583	DNA-binding transcription factor activity
CCK83_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS13430	COG1733	regulation of RNA biosynthetic process
CCK83_RS13435	COG0702	epimerase
CCK83_RS13490	COG3220	belongs to the UPF0276 family
CCK83_RS13500	COG1595	DNA-templated transcription, initiation
CCK83_RS13510	COG0583	DNA-binding transcription factor activity
CCK83_RS13515	COG1914	H( )-stimulated, divalent metal cation uptake system
CCK83_RS13535	COG4770	biotin carboxylase activity
CCK83_RS13540	COG0038	chloride channel
CCK83_RS13545	COG2831	hemolysin activation secretion protein
CCK83_RS13550	COG3210	domain, Protein
CCK83_RS13585	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCK83_RS13590	COG1063	alcohol dehydrogenase
CCK83_RS13605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCK83_RS13615	COG0789	Transcriptional regulator
CCK83_RS13635	COG1760	l-serine dehydratase
CCK83_RS13640	COG2030	dehydratase
CCK83_RS13640	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS13645	COG3396	Phenylacetate-CoA oxygenase
CCK83_RS13650	COG3460	Phenylacetate-CoA oxygenase
CCK83_RS13655	COG3396	Phenylacetate-CoA oxygenase
CCK83_RS13660	COG2151	metal-sulfur cluster biosynthetic enzyme
CCK83_RS13665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCK83_RS13670	COG1024	Enoyl-CoA hydratase
CCK83_RS13675	COG1024	Enoyl-CoA hydratase
CCK83_RS13680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCK83_RS13685	COG0183	Belongs to the thiolase family
CCK83_RS13690	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CCK83_RS13695	COG3327	negative regulation of DNA-templated transcription, initiation
CCK83_RS13705	COG2050	protein possibly involved in aromatic compounds catabolism
CCK83_RS13745	COG0583	DNA-binding transcription factor activity
CCK83_RS13755	COG1414	Transcriptional regulator
CCK83_RS13760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS13775	COG1840	ABC-type Fe3 transport system, periplasmic component
CCK83_RS13780	COG3842	ATPase activity
CCK83_RS13795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CCK83_RS13800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCK83_RS13805	COG2814	Major facilitator Superfamily
CCK83_RS13810	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS13825	COG1024	Enoyl-CoA hydratase
CCK83_RS13835	COG2814	Major facilitator Superfamily
CCK83_RS13845	COG0183	Belongs to the thiolase family
CCK83_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS13860	COG1024	Enoyl-CoA hydratase
CCK83_RS13865	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS13870	COG2814	Major facilitator Superfamily
CCK83_RS13875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CCK83_RS13880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCK83_RS13890	COG2814	Major facilitator Superfamily
CCK83_RS13900	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS13915	COG0583	DNA-binding transcription factor activity
CCK83_RS13925	COG4770	biotin carboxylase activity
CCK83_RS13930	COG1024	Enoyl-CoA hydratase
CCK83_RS13935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCK83_RS13940	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS13945	COG1309	transcriptional regulator
CCK83_RS13950	COG0318	PFAM AMP-dependent synthetase and ligase
CCK83_RS13965	COG2814	Major facilitator Superfamily
CCK83_RS13980	COG0583	DNA-binding transcription factor activity
CCK83_RS14020	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS14060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCK83_RS14080	COG2205	protein histidine kinase activity
CCK83_RS14080	COG0784	Response regulator, receiver
CCK83_RS14120	COG0765	amino acid transport
CCK83_RS14125	COG0765	amino acid transport
CCK83_RS14135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCK83_RS14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCK83_RS14150	COG1280	lysine exporter protein (LysE YggA)
CCK83_RS14155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCK83_RS14160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCK83_RS14165	COG1045	serine acetyltransferase
CCK83_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS14180	COG0583	DNA-binding transcription factor activity
CCK83_RS14200	COG0625	glutathione transferase activity
CCK83_RS14205	COG0625	glutathione transferase activity
CCK83_RS14210	COG0583	DNA-binding transcription factor activity
CCK83_RS14220	COG1346	cytolysis
CCK83_RS14245	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CCK83_RS14250	COG3052	prosthetic group binding
CCK83_RS14270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CCK83_RS14290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCK83_RS14300	COG1294	oxidase, subunit
CCK83_RS14305	COG1271	oxidase subunit
CCK83_RS14330	COG0477	Major facilitator Superfamily
CCK83_RS14340	COG4521	taurine ABC transporter
CCK83_RS14345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CCK83_RS14350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCK83_RS14355	COG2175	clavaminate synthase activity
CCK83_RS14365	COG1953	Uracil, thiamine, allantoin
CCK83_RS14375	COG0583	DNA-binding transcription factor activity
CCK83_RS14385	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CCK83_RS14400	COG0640	Transcriptional regulator
CCK83_RS14410	COG0798	PFAM Bile acid sodium symporter
CCK83_RS14415	COG0431	NADPH-dependent FMN reductase
CCK83_RS14420	COG0583	DNA-binding transcription factor activity
CCK83_RS14435	COG3634	alkyl hydroperoxide reductase activity
CCK83_RS14470	COG1301	dicarboxylic acid transport
CCK83_RS14475	COG0436	Aminotransferase
CCK83_RS14485	COG0386	Belongs to the glutathione peroxidase family
CCK83_RS14490	COG2207	Transcriptional regulator
CCK83_RS14490	COG1917	Cupin 2, conserved barrel domain protein
CCK83_RS14525	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CCK83_RS14550	COG0012	GTP binding
CCK83_RS14555	COG2011	ABC-type metal ion transport system permease component
CCK83_RS14560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCK83_RS14570	COG1464	Belongs to the NlpA lipoprotein family
CCK83_RS14600	COG0765	amino acid transport
CCK83_RS14605	COG0765	amino acid transport
CCK83_RS14610	COG1126	abc transporter atp-binding protein
CCK83_RS14620	COG1522	sequence-specific DNA binding
CCK83_RS14635	COG1309	transcriptional regulator
CCK83_RS14650	COG0583	DNA-binding transcription factor activity
CCK83_RS14660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CCK83_RS14670	COG0697	spore germination
CCK83_RS14675	COG0583	DNA-binding transcription factor activity
CCK83_RS14710	COG3539	Fimbrial protein
CCK83_RS14735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCK83_RS14735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCK83_RS14780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCK83_RS14790	COG2353	YceI-like domain
CCK83_RS14800	COG3698	Phosphodiester glycosidase
CCK83_RS14815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CCK83_RS14820	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCK83_RS14820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCK83_RS14820	COG0506	proline dehydrogenase activity
CCK83_RS14830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCK83_RS14835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCK83_RS14855	COG1132	(ABC) transporter
CCK83_RS14860	COG3122	Protein conserved in bacteria
CCK83_RS14865	COG3619	membrane
CCK83_RS14875	COG0640	Transcriptional regulator
CCK83_RS14885	COG2850	peptidyl-arginine hydroxylation
CCK83_RS14890	COG0424	maF-like protein
CCK83_RS14915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCK83_RS14925	COG3178	'Phosphotransferase
CCK83_RS14930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCK83_RS14940	COG1192	Involved in chromosome partitioning
CCK83_RS14945	COG1475	DNA binding
CCK83_RS14950	COG0811	peptide transport
CCK83_RS14960	COG1132	(ABC) transporter
CCK83_RS14965	COG1663	tetraacyldisaccharide 4'-kinase activity
CCK83_RS14985	COG0084	hydrolase, TatD family'
CCK83_RS15050	COG0776	regulation of translation
CCK83_RS15065	COG2431	L-lysine efflux transmembrane transporter activity
CCK83_RS15080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CCK83_RS15085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCK83_RS15125	COG4166	transmembrane transport
CCK83_RS15130	COG0339	signal peptide processing
CCK83_RS15135	COG0601	transmembrane transport
CCK83_RS15255	COG5005	Phage virion morphogenesis
CCK83_RS15260	COG2369	cell adhesion
CCK83_RS15265	COG4383	Mu-like prophage protein gp29
CCK83_RS15270	COG4373	Mu-like prophage FluMu protein gp28
CCK83_RS15430	COG0702	epimerase
CCK83_RS15435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCK83_RS15455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCK83_RS15485	COG0316	Belongs to the HesB IscA family
CCK83_RS15490	COG0822	iron-sulfur transferase activity
CCK83_RS15515	COG0776	regulation of translation
CCK83_RS15520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCK83_RS15525	COG2207	Transcriptional regulator
CCK83_RS15530	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCK83_RS15535	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS15540	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS15555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCK83_RS15580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CCK83_RS15600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCK83_RS15605	COG0730	response to heat
CCK83_RS15630	COG4773	Receptor
CCK83_RS15635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCK83_RS15695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCK83_RS15705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCK83_RS15710	COG0583	DNA-binding transcription factor activity
CCK83_RS15740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCK83_RS15750	COG0133	tryptophan synthase activity
CCK83_RS15770	COG3706	GGDEF domain
CCK83_RS15785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCK83_RS15790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CCK83_RS15795	COG0022	dehydrogenase e1 component
CCK83_RS15800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCK83_RS15805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCK83_RS15815	COG1063	alcohol dehydrogenase
CCK83_RS15820	COG3781	membrane
CCK83_RS15840	COG0730	response to heat
CCK83_RS15855	COG3708	Transcriptional regulator
CCK83_RS15855	COG2207	Transcriptional regulator
CCK83_RS15860	COG1733	regulation of RNA biosynthetic process
CCK83_RS15865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCK83_RS15875	COG0477	Major facilitator Superfamily
CCK83_RS15885	COG1027	Aspartate ammonia-lyase
CCK83_RS15900	COG0583	DNA-binding transcription factor activity
CCK83_RS15905	COG0583	DNA-binding transcription factor activity
CCK83_RS15910	COG0183	Belongs to the thiolase family
CCK83_RS15915	COG2031	fatty acid transporter
CCK83_RS15930	COG0583	DNA-binding transcription factor activity
CCK83_RS15970	COG2610	gluconate transmembrane transporter activity
CCK83_RS15975	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS15980	COG2207	Transcriptional regulator
CCK83_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCK83_RS16025	COG0543	2 iron, 2 sulfur cluster binding
CCK83_RS16025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCK83_RS16030	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CCK83_RS16035	COG4638	Rieske (2fe-2S)
CCK83_RS16045	COG0725	ABC transporter, periplasmic molybdate-binding protein
CCK83_RS16050	COG4149	molybdate abc transporter
CCK83_RS16055	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CCK83_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16065	COG1535	isochorismatase
CCK83_RS16065	COG3433	isochorismatase activity
CCK83_RS16120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCK83_RS16125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCK83_RS16130	COG0745	RESPONSE REGULATOR receiver
CCK83_RS16135	COG2205	protein histidine kinase activity
CCK83_RS16145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCK83_RS16165	COG0753	catalase activity
CCK83_RS16175	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CCK83_RS16195	COG2801	Transposase and inactivated derivatives
CCK83_RS16210	COG2207	Transcriptional regulator
CCK83_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16235	COG1073	alpha beta
CCK83_RS16295	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CCK83_RS16345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCK83_RS16360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCK83_RS16375	COG2084	Dehydrogenase
CCK83_RS16385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCK83_RS16395	COG0583	DNA-binding transcription factor activity
CCK83_RS16405	COG0129	dihydroxy-acid dehydratase activity
CCK83_RS16410	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS16435	COG2271	Major facilitator Superfamily
CCK83_RS16450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS16500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCK83_RS16505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCK83_RS16530	COG0583	DNA-binding transcription factor activity
CCK83_RS16590	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS16605	COG4993	Dehydrogenase
CCK83_RS16610	COG0583	DNA-binding transcription factor activity
CCK83_RS16620	COG2259	Doxx family
CCK83_RS16625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCK83_RS16655	COG0318	PFAM AMP-dependent synthetase and ligase
CCK83_RS16665	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16690	COG0583	DNA-binding transcription factor activity
CCK83_RS16695	COG1309	transcriptional regulator
CCK83_RS16735	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS16735	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCK83_RS16760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCK83_RS16765	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS16785	COG2186	Transcriptional regulator
CCK83_RS16795	COG0583	DNA-binding transcription factor activity
CCK83_RS16800	COG4948	Mandelate Racemase Muconate Lactonizing
CCK83_RS16805	COG4829	muconolactone delta-isomerase
CCK83_RS16815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CCK83_RS16820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCK83_RS16825	COG0183	Belongs to the thiolase family
CCK83_RS16830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCK83_RS16835	COG1012	belongs to the aldehyde dehydrogenase family
CCK83_RS16850	COG3733	amine oxidase
CCK83_RS16860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCK83_RS16870	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS16880	COG4638	Rieske (2fe-2S)
CCK83_RS16900	COG0154	amidase activity
CCK83_RS16910	COG2814	Major facilitator Superfamily
CCK83_RS16935	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS16940	COG0583	DNA-binding transcription factor activity
CCK83_RS16945	COG1414	Transcriptional regulator
CCK83_RS16960	COG2391	methyltransferase activity
CCK83_RS16970	COG4993	Dehydrogenase
CCK83_RS16975	COG3659	wide pore channel activity
CCK83_RS16980	COG3420	alginic acid biosynthetic process
CCK83_RS16985	COG0710	3-dehydroquinate dehydratase activity
CCK83_RS16990	COG3485	protocatechuate 3,4-dioxygenase
CCK83_RS16995	COG3485	protocatechuate 3,4-dioxygenase
CCK83_RS17000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCK83_RS17005	COG2271	Major facilitator Superfamily
CCK83_RS17010	COG0596	Alpha beta hydrolase
CCK83_RS17015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCK83_RS17020	COG0183	Belongs to the thiolase family
CCK83_RS17025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCK83_RS17030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CCK83_RS17040	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CCK83_RS17050	COG4773	Receptor
CCK83_RS17065	COG2323	membrane
CCK83_RS17070	COG0148	phosphopyruvate hydratase activity
CCK83_RS17110	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS17110	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCK83_RS17135	COG0542	response to heat
CCK83_RS17140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCK83_RS17170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCK83_RS17175	COG0569	domain protein
CCK83_RS17180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CCK83_RS17195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCK83_RS17205	COG1585	Membrane protein implicated in regulation of membrane protease activity
CCK83_RS17220	COG1294	oxidase, subunit
CCK83_RS17225	COG4890	Cyd operon protein YbgT
CCK83_RS17250	COG0552	protein localization to endoplasmic reticulum
CCK83_RS17275	COG0517	IMP dehydrogenase activity
CCK83_RS17275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CCK83_RS17280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCK83_RS17285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCK83_RS17295	COG0583	DNA-binding transcription factor activity
CCK83_RS17300	COG0024	Methionine aminopeptidase
CCK83_RS17310	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CCK83_RS17330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCK83_RS17330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCK83_RS17335	COG1105	Belongs to the carbohydrate kinase PfkB family
CCK83_RS17340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCK83_RS17340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CCK83_RS17340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCK83_RS17355	COG5001	Diguanylate cyclase
CCK83_RS17355	COG3300	MHYT domain
CCK83_RS17375	COG0659	secondary active sulfate transmembrane transporter activity
CCK83_RS17385	COG0659	secondary active sulfate transmembrane transporter activity
CCK83_RS17400	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS17410	COG1113	amino acid transport
CCK83_RS17420	COG1522	sequence-specific DNA binding
CCK83_RS17440	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS17445	COG3118	belongs to the thioredoxin family
CCK83_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS17455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCK83_RS17475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCK83_RS17545	COG0592	DNA-directed DNA polymerase activity
CCK83_RS17590	COG2026	Addiction module toxin, RelE StbE family
CCK83_RS17720	COG2369	cell adhesion
CCK83_RS17745	COG3755	Protein conserved in bacteria
CCK83_RS17845	COG1484	DNA-dependent DNA replication
CCK83_RS17925	COG1011	Hydrolase
CCK83_RS17930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCK83_RS17940	COG2137	regulation of response to DNA damage stimulus
CCK83_RS17955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCK83_RS17990	COG0575	Belongs to the CDS family
CCK83_RS17995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCK83_RS18020	COG3852	Histidine kinase
CCK83_RS18025	COG2204	response regulator
CCK83_RS18095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCK83_RS18120	COG0697	spore germination
CCK83_RS18125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCK83_RS18135	COG0303	'Molybdopterin
CCK83_RS18140	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCK83_RS18140	COG0315	cyclic pyranopterin monophosphate synthase activity
CCK83_RS18155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCK83_RS18160	COG0243	molybdopterin cofactor binding
CCK83_RS18170	COG0243	molybdopterin cofactor binding
CCK83_RS18175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCK83_RS18180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCK83_RS18180	COG2146	nitrite reductase [NAD(P)H] activity
CCK83_RS18195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCK83_RS18195	COG1116	anion transmembrane transporter activity
CCK83_RS18205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCK83_RS18210	COG2423	ornithine cyclodeaminase activity
CCK83_RS18215	COG4264	IucA IucC family
CCK83_RS18225	COG4264	IucA IucC family
CCK83_RS18250	COG0511	ligase activity, forming carbon-carbon bonds
CCK83_RS18265	COG2814	Major facilitator Superfamily
CCK83_RS18290	COG0069	glutamate synthase activity
CCK83_RS18320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCK83_RS18345	COG1454	alcohol dehydrogenase
CCK83_RS18350	COG0824	Thioesterase
CCK83_RS18360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCK83_RS18390	COG2030	dehydratase
CCK83_RS18400	COG0183	Belongs to the thiolase family
CCK83_RS18410	COG0583	DNA-binding transcription factor activity
CCK83_RS18415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCK83_RS18425	COG1522	sequence-specific DNA binding
CCK83_RS18430	COG3135	benzoate transporter
CCK83_RS18450	COG0589	response to stress
CCK83_RS18455	COG0488	(ABC) transporter
CCK83_RS18485	COG0583	DNA-binding transcription factor activity
CCK83_RS18515	COG3772	lysozyme
CCK83_RS18560	COG4772	TonB-dependent receptor
CCK83_RS18575	COG1605	Chorismate mutase
CCK83_RS18615	COG0308	aminopeptidase N
CCK83_RS18640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCK83_RS18645	COG1454	alcohol dehydrogenase
CCK83_RS18665	COG0531	amino acid
CCK83_RS18670	COG4303	Ethanolamine ammonia lyase large subunit
CCK83_RS18675	COG4302	ethanolamine ammonia-lyase activity
CCK83_RS18680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCK83_RS18680	COG0519	Catalyzes the synthesis of GMP from XMP
CCK83_RS18685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCK83_RS18710	COG0697	spore germination
CCK83_RS18715	COG1923	regulation of RNA biosynthetic process
CCK83_RS18725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCK83_RS18730	COG0802	atpase or kinase
CCK83_RS18750	COG1187	pseudouridine synthase activity
CCK83_RS18765	COG0583	DNA-binding transcription factor activity
CCK83_RS18855	COG4397	Mu-like prophage major head subunit gpT
CCK83_RS18870	COG5005	Phage virion morphogenesis
CCK83_RS18875	COG2369	cell adhesion
CCK83_RS18880	COG4383	Mu-like prophage protein gp29
CCK83_RS18895	COG4373	Mu-like prophage FluMu protein gp28
CCK83_RS18930	COG0681	Belongs to the peptidase S26 family
CCK83_RS18955	COG3409	Peptidoglycan-binding domain 1 protein
CCK83_RS18955	COG3267	Type II secretory pathway component ExeA
CCK83_RS18985	COG0776	regulation of translation
CCK83_RS19030	COG2814	Major facilitator Superfamily
CCK83_RS19035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCK83_RS19045	COG0471	metal ion transport
CCK83_RS19085	COG0729	surface antigen
CCK83_RS19090	COG0477	Major facilitator Superfamily
CCK83_RS19105	COG0174	glutamine synthetase
CCK83_RS19110	COG0745	RESPONSE REGULATOR receiver
CCK83_RS19115	COG2205	protein histidine kinase activity
CCK83_RS19125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CCK83_RS19130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CCK83_RS19140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CCK83_RS19155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCK83_RS19160	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS19175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCK83_RS19180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCK83_RS19200	COG0583	DNA-binding transcription factor activity
CCK83_RS19215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCK83_RS19225	COG3658	cytochrome
CCK83_RS19230	COG1215	transferase activity, transferring glycosyl groups
CCK83_RS19235	COG1649	PFAM Uncharacterised BCR, COG1649
CCK83_RS19235	COG0726	polysaccharide deacetylase
CCK83_RS19265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCK83_RS19270	COG1845	cytochrome c oxidase, subunit III
CCK83_RS19275	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCK83_RS19300	COG0305	Participates in initiation and elongation during chromosome replication
CCK83_RS19305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCK83_RS19315	COG1305	Transglutaminase-like
CCK83_RS19325	COG2308	Evidence 4 Homologs of previously reported genes of
CCK83_RS19355	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CCK83_RS19365	COG0151	Belongs to the GarS family
CCK83_RS19375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCK83_RS19380	COG2011	ABC-type metal ion transport system permease component
CCK83_RS19385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCK83_RS19395	COG1301	dicarboxylic acid transport
CCK83_RS19425	COG1794	racemase activity, acting on amino acids and derivatives
CCK83_RS19440	COG0745	RESPONSE REGULATOR receiver
CCK83_RS19445	COG0642	Histidine kinase
CCK83_RS19450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCK83_RS19460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCK83_RS19510	COG3008	intermembrane lipid transfer
CCK83_RS19510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCK83_RS19515	COG2995	paraquat-inducible protein a
CCK83_RS19530	COG2985	domain, Protein
CCK83_RS19540	COG1309	transcriptional regulator
CCK83_RS19605	COG1028	Short-chain dehydrogenase reductase Sdr
CCK83_RS19610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCK83_RS19610	COG0475	glutathione-regulated potassium exporter activity
CCK83_RS19615	COG0786	glutamate:sodium symporter activity
CCK83_RS19620	COG3243	poly(R)-hydroxyalkanoic acid synthase
CCK83_RS19635	COG1278	Cold shock
CCK83_RS19660	COG0515	serine threonine protein kinase
CCK83_RS19660	COG2815	serine threonine protein kinase
CCK83_RS19690	COG1610	YqeY-like protein
CCK83_RS19695	COG4783	chaperone-mediated protein folding
CCK83_RS19720	COG1286	toxin biosynthetic process
CCK83_RS19750	COG0778	Nitroreductase
CCK83_RS19760	COG0513	Belongs to the DEAD box helicase family
CCK83_RS19780	COG2363	Small membrane protein
CCK83_RS19805	COG4650	regulator
CCK83_RS19810	COG1234	tRNA 3'-trailer cleavage
CCK83_RS19815	COG1690	Belongs to the RtcB family
CCK83_RS19835	COG2195	Cleaves the N-terminal amino acid of tripeptides
CCK83_RS19840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCK83_RS19850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCK83_RS19865	COG1960	acyl-CoA dehydrogenase activity
CCK83_RS19870	COG1301	dicarboxylic acid transport
CCK83_RS19880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCK83_RS19885	COG3139	Protein of unknown function (DUF1315)
CCK83_RS19890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCK83_RS19930	COG3328	transposase activity
CCK83_RS19940	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CCK83_RS19980	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CCK83_RS19995	COG2801	Transposase and inactivated derivatives
CCK83_RS20015	COG4221	oxidoreductase activity
CCK83_RS20020	COG0583	DNA-binding transcription factor activity
CCK83_RS20025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CCK83_RS20030	COG0604	alcohol dehydrogenase
CCK83_RS20030	COG3321	synthase
CCK83_RS20035	COG0583	DNA-binding transcription factor activity
CCK83_RS20045	COG3657	addiction module killer protein
CCK83_RS20050	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCK83_RS20070	COG2801	Transposase and inactivated derivatives
CCK83_RS20095	COG3657	addiction module killer protein
CCK83_RS20100	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCK83_RS20105	COG3328	transposase activity
CCK83_RS20125	COG1063	alcohol dehydrogenase
CCK83_RS20140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCK83_RS20140	COG0475	glutathione-regulated potassium exporter activity
CCK83_RS20175	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CCK83_RS20185	COG1979	alcohol dehydrogenase
CCK83_RS20195	COG1902	pentaerythritol trinitrate reductase activity
CCK83_RS20205	COG1309	transcriptional regulator
CCK83_RS20210	COG2130	NADP-dependent
CCK83_RS20225	COG0582	viral genome integration into host DNA
CCK83_RS20245	COG0789	Transcriptional regulator
CCK83_RS20265	COG1373	ATPase (AAA superfamily
CCK83_RS20310	COG2132	Multicopper oxidase
CCK83_RS20315	COG3667	copper resistance
CCK83_RS20375	COG2826	transposase and inactivated derivatives, IS30 family
CCK83_RS20395	COG2217	Heavy metal translocating P-type atpase
CCK83_RS20400	COG3174	membrane
CCK83_RS20405	COG2205	protein histidine kinase activity
CCK83_RS20420	COG2132	Multicopper oxidase
CCK83_RS20445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family