locus-tag	class	description
IEC338SC_RS00010	COG0592	DNA-directed DNA polymerase activity
IEC338SC_RS00020	COG0187	DNA topoisomerase II activity
IEC338SC_RS00035	COG0488	(ABC) transporter
IEC338SC_RS00060	COG0596	Alpha beta hydrolase
IEC338SC_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IEC338SC_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEC338SC_RS00105	COG0625	glutathione transferase activity
IEC338SC_RS00115	COG0733	neurotransmitter:sodium symporter activity
IEC338SC_RS00150	COG2233	PERMEase
IEC338SC_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_RS00200	COG2814	Major facilitator Superfamily
IEC338SC_RS00205	COG0656	L-ascorbic acid biosynthetic process
IEC338SC_RS00210	COG0583	DNA-binding transcription factor activity
IEC338SC_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_RS00225	COG1064	alcohol dehydrogenase
IEC338SC_RS00230	COG2818	Glycosylase
IEC338SC_RS00245	COG1194	a g-specific adenine glycosylase
IEC338SC_RS00260	COG2983	Belongs to the UPF0260 family
IEC338SC_RS00265	COG2133	pyrroloquinoline quinone binding
IEC338SC_RS00270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IEC338SC_RS00275	COG2116	formate transmembrane transporter activity
IEC338SC_RS00295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEC338SC_RS00300	COG1335	isochorismatase
IEC338SC_RS00305	COG0385	Bile acid
IEC338SC_RS00310	COG0534	Mate efflux family protein
IEC338SC_RS00315	COG1683	Conserved Protein
IEC338SC_RS00330	COG0346	lactoylglutathione lyase activity
IEC338SC_RS00335	COG0625	glutathione transferase activity
IEC338SC_RS00345	COG1113	amino acid transport
IEC338SC_RS00355	COG0523	cobalamin synthesis protein
IEC338SC_RS00365	COG2188	Transcriptional regulator
IEC338SC_RS00395	COG0010	Belongs to the arginase family
IEC338SC_RS00405	COG0546	phosphoglycolate phosphatase activity
IEC338SC_RS00410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IEC338SC_RS00415	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IEC338SC_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IEC338SC_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IEC338SC_RS00550	COG0534	Mate efflux family protein
IEC338SC_RS00555	COG0436	Aminotransferase
IEC338SC_RS00560	COG2733	membrane
IEC338SC_RS00575	COG2918	glutathione biosynthetic process
IEC338SC_RS00605	COG3150	esterase
IEC338SC_RS00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IEC338SC_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_RS00635	COG2233	PERMEase
IEC338SC_RS00640	COG2351	hydroxyisourate hydrolase activity
IEC338SC_RS00675	COG3706	GGDEF domain
IEC338SC_RS00690	COG1393	Belongs to the ArsC family
IEC338SC_RS00695	COG0708	Exodeoxyribonuclease III
IEC338SC_RS00725	COG0189	ligase activity
IEC338SC_RS00745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IEC338SC_RS00755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEC338SC_RS00770	COG4942	peptidase
IEC338SC_RS00780	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEC338SC_RS00790	COG2119	membrane
IEC338SC_RS00800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_RS00800	COG0426	domain, Protein
IEC338SC_RS00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IEC338SC_RS00840	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_RS00845	COG1519	Transferase
IEC338SC_RS00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IEC338SC_RS00855	COG0668	transmembrane transport
IEC338SC_RS00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEC338SC_RS00870	COG1335	isochorismatase
IEC338SC_RS00875	COG1522	sequence-specific DNA binding
IEC338SC_RS00900	COG0784	Response regulator, receiver
IEC338SC_RS00900	COG2205	protein histidine kinase activity
IEC338SC_RS00900	COG2198	Histidine kinase
IEC338SC_RS00905	COG3162	membrane
IEC338SC_RS00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEC338SC_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEC338SC_RS00940	COG1309	transcriptional regulator
IEC338SC_RS00960	COG0300	oxidoreductase activity
IEC338SC_RS00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IEC338SC_RS00970	COG0352	thiamine-phosphate diphosphorylase activity
IEC338SC_RS00970	COG0351	phosphomethylpyrimidine kinase
IEC338SC_RS00980	COG2814	Major facilitator Superfamily
IEC338SC_RS00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IEC338SC_RS01020	COG1113	amino acid transport
IEC338SC_RS01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_RS01035	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS01045	COG1335	isochorismatase
IEC338SC_RS01075	COG2814	Major facilitator Superfamily
IEC338SC_RS01080	COG0583	DNA-binding transcription factor activity
IEC338SC_RS01100	COG0667	Aldo Keto reductase
IEC338SC_RS01110	COG1309	transcriptional regulator
IEC338SC_RS01130	COG1733	regulation of RNA biosynthetic process
IEC338SC_RS01135	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_RS01200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEC338SC_RS01215	COG2329	Antibiotic biosynthesis monooxygenase
IEC338SC_RS01220	COG0697	spore germination
IEC338SC_RS01230	COG4619	ABC transporter
IEC338SC_RS01240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IEC338SC_RS01250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEC338SC_RS01280	COG0427	acetyl-CoA hydrolase
IEC338SC_RS01300	COG0659	secondary active sulfate transmembrane transporter activity
IEC338SC_RS01305	COG4221	oxidoreductase activity
IEC338SC_RS01315	COG2814	Major facilitator Superfamily
IEC338SC_RS01325	COG2873	o-acetylhomoserine
IEC338SC_RS01330	COG0488	(ABC) transporter
IEC338SC_RS01405	COG0833	amino acid
IEC338SC_RS01450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEC338SC_RS01455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IEC338SC_RS01470	COG2226	methyltransferase
IEC338SC_RS01520	COG0069	glutamate synthase activity
IEC338SC_RS01520	COG0067	glutamate synthase
IEC338SC_RS01520	COG0070	glutamate synthase
IEC338SC_RS01525	COG0493	'glutamate synthase
IEC338SC_RS01535	COG1704	LemA family
IEC338SC_RS01540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IEC338SC_RS01550	COG4969	Belongs to the N-Me-Phe pilin family
IEC338SC_RS01560	COG2801	Transposase and inactivated derivatives
IEC338SC_RS01565	COG3307	-O-antigen
IEC338SC_RS01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEC338SC_RS01595	COG0194	GDP metabolic process
IEC338SC_RS01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEC338SC_RS01655	COG0335	large ribosomal subunit rRNA binding
IEC338SC_RS01665	COG5380	lipid catabolic process
IEC338SC_RS01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEC338SC_RS01690	COG5006	permease, DMT superfamily
IEC338SC_RS01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IEC338SC_RS01700	COG0277	FAD linked oxidase domain protein
IEC338SC_RS01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IEC338SC_RS01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_RS01730	COG1289	transmembrane transporter activity
IEC338SC_RS01740	COG0628	permease
IEC338SC_RS01745	COG1192	Involved in chromosome partitioning
IEC338SC_RS01775	COG0833	amino acid
IEC338SC_RS01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEC338SC_RS01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEC338SC_RS01795	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS01835	COG0583	DNA-binding transcription factor activity
IEC338SC_RS01865	COG0752	glycyl-tRNA synthetase alpha subunit
IEC338SC_RS01885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IEC338SC_RS01885	COG0617	tRNA 3'-terminal CCA addition
IEC338SC_RS01885	COG0517	IMP dehydrogenase activity
IEC338SC_RS01890	COG1983	PspC domain protein
IEC338SC_RS01900	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS01915	COG0408	coproporphyrinogen oxidase activity
IEC338SC_RS01935	COG0513	Belongs to the DEAD box helicase family
IEC338SC_RS01945	COG1127	ABC transporter
IEC338SC_RS01950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IEC338SC_RS01960	COG2854	intermembrane phospholipid transfer
IEC338SC_RS01970	COG0598	Magnesium transport protein CorA
IEC338SC_RS01980	COG0494	nUDIX hydrolase
IEC338SC_RS01985	COG1040	competence protein
IEC338SC_RS01990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEC338SC_RS02005	COG2937	Belongs to the GPAT DAPAT family
IEC338SC_RS02010	COG1946	Acyl-CoA thioesterase
IEC338SC_RS02015	COG1301	dicarboxylic acid transport
IEC338SC_RS02030	COG1959	2 iron, 2 sulfur cluster binding
IEC338SC_RS02035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_RS02035	COG1017	nitric oxide dioxygenase activity
IEC338SC_RS02040	COG0433	COG0433 Predicted ATPase
IEC338SC_RS02045	COG0626	cystathionine gamma-synthase activity
IEC338SC_RS02060	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEC338SC_RS02065	COG0088	Forms part of the polypeptide exit tunnel
IEC338SC_RS02200	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS02205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IEC338SC_RS02235	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IEC338SC_RS02240	COG0339	signal peptide processing
IEC338SC_RS02245	COG0557	exoribonuclease II activity
IEC338SC_RS02290	COG0179	Fumarylacetoacetate (FAA) hydrolase
IEC338SC_RS02295	COG1295	ribonuclease BN
IEC338SC_RS02330	COG1702	phosphate starvation-inducible protein PhoH
IEC338SC_RS02340	COG0741	lytic transglycosylase activity
IEC338SC_RS02340	COG1196	nuclear chromosome segregation
IEC338SC_RS02340	COG0739	heme binding
IEC338SC_RS02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IEC338SC_RS02375	COG1183	phosphatidylcholine synthase activity
IEC338SC_RS02420	COG1047	Peptidyl-prolyl cis-trans
IEC338SC_RS02430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEC338SC_RS02435	COG0196	riboflavin kinase activity
IEC338SC_RS02445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEC338SC_RS02450	COG1309	transcriptional regulator
IEC338SC_RS02455	COG1116	anion transmembrane transporter activity
IEC338SC_RS02460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEC338SC_RS02465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEC338SC_RS02470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_RS02475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_RS02480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IEC338SC_RS02480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IEC338SC_RS02495	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS02500	COG0546	phosphoglycolate phosphatase activity
IEC338SC_RS02550	COG3023	N-Acetylmuramoyl-L-alanine amidase
IEC338SC_RS02555	COG0728	peptidoglycan biosynthetic process
IEC338SC_RS02580	COG1596	polysaccharide export
IEC338SC_RS02585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IEC338SC_RS02590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IEC338SC_RS02595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IEC338SC_RS02605	COG0438	transferase activity, transferring glycosyl groups
IEC338SC_RS02625	COG1063	alcohol dehydrogenase
IEC338SC_RS02640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IEC338SC_RS02650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEC338SC_RS02660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IEC338SC_RS02675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEC338SC_RS02680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEC338SC_RS02685	COG1620	l-lactate permease
IEC338SC_RS02690	COG2186	Transcriptional regulator
IEC338SC_RS02700	COG0277	FAD linked oxidase domain protein
IEC338SC_RS02705	COG1448	Aminotransferase
IEC338SC_RS02710	COG1802	Transcriptional regulator
IEC338SC_RS02725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IEC338SC_RS02740	COG1051	belongs to the nudix hydrolase family
IEC338SC_RS02770	COG2801	Transposase and inactivated derivatives
IEC338SC_RS02790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEC338SC_RS02800	COG1309	transcriptional regulator
IEC338SC_RS02825	COG0564	pseudouridine synthase activity
IEC338SC_RS02865	COG0251	oxidation-reduction process
IEC338SC_RS02870	COG1113	amino acid transport
IEC338SC_RS02875	COG1113	amino acid transport
IEC338SC_RS02895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEC338SC_RS02900	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS02905	COG1024	Enoyl-CoA hydratase
IEC338SC_RS02910	COG1024	Enoyl-CoA hydratase
IEC338SC_RS02915	COG0477	Major facilitator Superfamily
IEC338SC_RS02920	COG3916	Acyl-homoserine-lactone synthase
IEC338SC_RS02930	COG2197	response regulator
IEC338SC_RS02940	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS02945	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IEC338SC_RS02945	COG3321	synthase
IEC338SC_RS02945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEC338SC_RS02945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IEC338SC_RS02985	COG0271	Belongs to the BolA IbaG family
IEC338SC_RS02995	COG1192	Involved in chromosome partitioning
IEC338SC_RS03010	COG0586	Pfam SNARE associated Golgi protein
IEC338SC_RS03015	COG2259	Doxx family
IEC338SC_RS03020	COG4399	Belongs to the UPF0754 family
IEC338SC_RS03025	COG0519	Catalyzes the synthesis of GMP from XMP
IEC338SC_RS03025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IEC338SC_RS03030	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IEC338SC_RS03085	COG0281	malic enzyme
IEC338SC_RS03090	COG2837	iron assimilation
IEC338SC_RS03095	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS03100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IEC338SC_RS03105	COG1121	(ABC) transporter
IEC338SC_RS03145	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEC338SC_RS03155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEC338SC_RS03170	COG0386	Belongs to the glutathione peroxidase family
IEC338SC_RS03185	COG1309	transcriptional regulator
IEC338SC_RS03190	COG0697	spore germination
IEC338SC_RS03200	COG0758	DNA mediated transformation
IEC338SC_RS03235	COG1309	transcriptional regulator
IEC338SC_RS03270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEC338SC_RS03285	COG0655	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_RS03325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEC338SC_RS03335	COG2814	Major facilitator Superfamily
IEC338SC_RS03345	COG1253	flavin adenine dinucleotide binding
IEC338SC_RS03355	COG2860	membrane
IEC338SC_RS03360	COG0477	Major facilitator Superfamily
IEC338SC_RS03370	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_RS03385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IEC338SC_RS03405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEC338SC_RS03410	COG0235	Class ii aldolase
IEC338SC_RS03415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_RS03425	COG0606	chelatase, subunit chli
IEC338SC_RS03435	COG0347	Belongs to the P(II) protein family
IEC338SC_RS03440	COG0004	ammonium transporteR
IEC338SC_RS03450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEC338SC_RS03450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEC338SC_RS03490	COG0795	lipopolysaccharide-transporting ATPase activity
IEC338SC_RS03495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEC338SC_RS03500	COG0793	Belongs to the peptidase S41A family
IEC338SC_RS03515	COG2197	response regulator
IEC338SC_RS03525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IEC338SC_RS03535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEC338SC_RS03540	COG4974	Belongs to the 'phage' integrase family
IEC338SC_RS03565	COG0772	Belongs to the SEDS family
IEC338SC_RS03570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEC338SC_RS03575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IEC338SC_RS03580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IEC338SC_RS03605	COG0697	spore germination
IEC338SC_RS03610	COG1538	Outer membrane efflux protein
IEC338SC_RS03630	COG3275	phosphorelay sensor kinase activity
IEC338SC_RS03640	COG0181	hydroxymethylbilane synthase activity
IEC338SC_RS03685	COG1716	ATPase activity
IEC338SC_RS03690	COG0546	phosphoglycolate phosphatase activity
IEC338SC_RS03720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEC338SC_RS03790	COG2056	Na+-H+ antiporter family
IEC338SC_RS03805	COG0326	Molecular chaperone. Has ATPase activity
IEC338SC_RS03820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IEC338SC_RS03885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEC338SC_RS03890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEC338SC_RS03890	COG2169	Transcriptional regulator
IEC338SC_RS03920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEC338SC_RS03930	COG0497	DNA recombination
IEC338SC_RS03945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEC338SC_RS03955	COG0237	dephospho-CoA kinase activity
IEC338SC_RS04005	COG0195	Participates in both transcription termination and antitermination
IEC338SC_RS04015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEC338SC_RS04020	COG1320	monovalent cation:proton antiporter activity
IEC338SC_RS04025	COG2212	antiporter activity
IEC338SC_RS04030	COG1863	multisubunit Na H antiporter MnhE subunit
IEC338SC_RS04035	COG0651	ATP synthesis coupled electron transport
IEC338SC_RS04040	COG1006	Multisubunit Na H antiporter MnhC subunit
IEC338SC_RS04045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IEC338SC_RS04045	COG2111	Na H antiporter
IEC338SC_RS04060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IEC338SC_RS04075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IEC338SC_RS04085	COG2226	methyltransferase
IEC338SC_RS04105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IEC338SC_RS04110	COG1074	ATP-dependent DNA helicase activity
IEC338SC_RS04115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IEC338SC_RS04120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IEC338SC_RS04130	COG1185	polyribonucleotide nucleotidyltransferase activity
IEC338SC_RS04135	COG0598	Magnesium transport protein CorA
IEC338SC_RS04140	COG0789	Transcriptional regulator
IEC338SC_RS04145	COG0484	heat shock protein binding
IEC338SC_RS04155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEC338SC_RS04165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEC338SC_RS04185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEC338SC_RS04195	COG4535	Mg2 and Co2 transporter CorC
IEC338SC_RS04210	COG0644	oxidoreductase
IEC338SC_RS04210	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IEC338SC_RS04220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IEC338SC_RS04235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_RS04240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IEC338SC_RS04250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEC338SC_RS04250	COG0493	'glutamate synthase
IEC338SC_RS04275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IEC338SC_RS04290	COG0534	Mate efflux family protein
IEC338SC_RS04300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IEC338SC_RS04305	COG4221	oxidoreductase activity
IEC338SC_RS04310	COG0583	DNA-binding transcription factor activity
IEC338SC_RS04325	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_RS04330	COG1530	ribonuclease E activity
IEC338SC_RS04345	COG2378	regulation of single-species biofilm formation
IEC338SC_RS04350	COG0625	glutathione transferase activity
IEC338SC_RS04360	COG0583	DNA-binding transcription factor activity
IEC338SC_RS04400	COG0583	DNA-binding transcription factor activity
IEC338SC_RS04425	COG0473	3-isopropylmalate dehydrogenase activity
IEC338SC_RS04480	COG1301	dicarboxylic acid transport
IEC338SC_RS04490	COG1560	Kdo2-lipid A biosynthetic process
IEC338SC_RS04500	COG0488	(ABC) transporter
IEC338SC_RS04505	COG2900	Belongs to the SlyX family
IEC338SC_RS04510	COG0604	alcohol dehydrogenase
IEC338SC_RS04515	COG1733	regulation of RNA biosynthetic process
IEC338SC_RS04540	COG0210	DNA helicase
IEC338SC_RS04545	COG0724	RNA recognition motif
IEC338SC_RS04565	COG4651	solute:proton antiporter activity
IEC338SC_RS04565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IEC338SC_RS04590	COG0788	formyltetrahydrofolate deformylase activity
IEC338SC_RS04690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEC338SC_RS04690	COG2813	Specifically methylates the guanine in position
IEC338SC_RS04700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IEC338SC_RS04710	COG4774	siderophore transport
IEC338SC_RS04720	COG0740	serine-type endopeptidase activity
IEC338SC_RS04740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IEC338SC_RS04740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IEC338SC_RS04745	COG0280	phosphate acetyltransferase
IEC338SC_RS04745	COG0857	belongs to the CobB CobQ family
IEC338SC_RS04750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEC338SC_RS04760	COG0800	Aldolase
IEC338SC_RS04770	COG3265	gluconokinase activity
IEC338SC_RS04775	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS04785	COG2267	carboxylic ester hydrolase activity
IEC338SC_RS04800	COG0793	Belongs to the peptidase S41A family
IEC338SC_RS04835	COG1426	Protein conserved in bacteria
IEC338SC_RS04855	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEC338SC_RS04880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEC338SC_RS04895	COG1216	Glycosyl transferase, family 2
IEC338SC_RS04905	COG2986	histidine ammonia-lyase
IEC338SC_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS04950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IEC338SC_RS04970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IEC338SC_RS04980	COG1162	GTPase activity
IEC338SC_RS04985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IEC338SC_RS05005	COG1136	(ABC) transporter
IEC338SC_RS05005	COG0577	efflux transmembrane transporter activity
IEC338SC_RS05010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_RS05030	COG0028	Belongs to the TPP enzyme family
IEC338SC_RS05035	COG0440	acetolactate synthase activity
IEC338SC_RS05040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IEC338SC_RS05050	COG1309	transcriptional regulator
IEC338SC_RS05060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IEC338SC_RS05075	COG0084	hydrolase, TatD family'
IEC338SC_RS05085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IEC338SC_RS05090	COG0583	DNA-binding transcription factor activity
IEC338SC_RS05105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEC338SC_RS05110	COG2814	Major facilitator Superfamily
IEC338SC_RS05120	COG0697	spore germination
IEC338SC_RS05155	COG3622	Belongs to the hyi family
IEC338SC_RS05160	COG2084	Dehydrogenase
IEC338SC_RS05165	COG1024	Enoyl-CoA hydratase
IEC338SC_RS05170	COG2205	protein histidine kinase activity
IEC338SC_RS05170	COG5002	protein histidine kinase activity
IEC338SC_RS05170	COG0784	Response regulator, receiver
IEC338SC_RS05175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEC338SC_RS05190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEC338SC_RS05215	COG4221	oxidoreductase activity
IEC338SC_RS05220	COG3956	TIGRFAM MazG family protein
IEC338SC_RS05225	COG1555	photosystem II stabilization
IEC338SC_RS05230	COG0617	tRNA 3'-terminal CCA addition
IEC338SC_RS05235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IEC338SC_RS05255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEC338SC_RS05260	COG3028	Belongs to the UPF0307 family
IEC338SC_RS05265	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_RS05285	COG0625	glutathione transferase activity
IEC338SC_RS05290	COG1238	metal cluster binding
IEC338SC_RS05305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IEC338SC_RS05325	COG0072	phenylalanine-tRNA ligase activity
IEC338SC_RS05350	COG0248	Ppx GppA phosphatase
IEC338SC_RS05360	COG0037	tRNA processing
IEC338SC_RS05375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEC338SC_RS05375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEC338SC_RS05400	COG1764	response to oxidative stress
IEC338SC_RS05405	COG1846	Transcriptional regulator
IEC338SC_RS05415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEC338SC_RS05475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEC338SC_RS05480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IEC338SC_RS05485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEC338SC_RS05545	COG1214	PFAM Peptidase M22, glycoprotease
IEC338SC_RS05570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IEC338SC_RS05575	COG0561	phosphatase activity
IEC338SC_RS05585	COG2132	Multicopper oxidase
IEC338SC_RS05605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEC338SC_RS05610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEC338SC_RS05615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IEC338SC_RS05645	COG1063	alcohol dehydrogenase
IEC338SC_RS05650	COG0583	DNA-binding transcription factor activity
IEC338SC_RS05655	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS05660	COG2814	Major facilitator Superfamily
IEC338SC_RS05665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IEC338SC_RS05690	COG1053	succinate dehydrogenase
IEC338SC_RS05695	COG0583	DNA-binding transcription factor activity
IEC338SC_RS05710	COG0583	DNA-binding transcription factor activity
IEC338SC_RS05740	COG0583	DNA-binding transcription factor activity
IEC338SC_RS05755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_RS05810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEC338SC_RS05820	COG0745	RESPONSE REGULATOR receiver
IEC338SC_RS05835	COG2199	diguanylate cyclase activity
IEC338SC_RS05860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IEC338SC_RS05890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IEC338SC_RS05895	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IEC338SC_RS05915	COG0583	DNA-binding transcription factor activity
IEC338SC_RS05935	COG0668	transmembrane transport
IEC338SC_RS05940	COG2081	HI0933 family
IEC338SC_RS05945	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IEC338SC_RS05980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEC338SC_RS05980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEC338SC_RS05990	COG0489	protein tyrosine kinase activity
IEC338SC_RS05995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEC338SC_RS06040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEC338SC_RS06050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEC338SC_RS06065	COG0730	response to heat
IEC338SC_RS06075	COG1196	nuclear chromosome segregation
IEC338SC_RS06095	COG2223	nitrite transmembrane transporter activity
IEC338SC_RS06100	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IEC338SC_RS06110	COG2226	methyltransferase
IEC338SC_RS06110	COG0596	Alpha beta hydrolase
IEC338SC_RS06110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEC338SC_RS06125	COG4106	trans-aconitate 2-methyltransferase activity
IEC338SC_RS06140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEC338SC_RS06145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEC338SC_RS06150	COG0009	L-threonylcarbamoyladenylate synthase
IEC338SC_RS06155	COG3101	peptidyl-lysine hydroxylation
IEC338SC_RS06160	COG1399	metal-binding, possibly nucleic acid-binding protein
IEC338SC_RS06185	COG1652	LysM domain
IEC338SC_RS06190	COG0351	phosphomethylpyrimidine kinase
IEC338SC_RS06200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IEC338SC_RS06230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEC338SC_RS06260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IEC338SC_RS06275	COG0358	DNA primase activity
IEC338SC_RS06310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEC338SC_RS06330	COG0583	DNA-binding transcription factor activity
IEC338SC_RS06335	COG0473	3-isopropylmalate dehydrogenase activity
IEC338SC_RS06345	COG0657	acetylesterase activity
IEC338SC_RS06350	COG4638	Rieske (2fe-2S)
IEC338SC_RS06355	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS06375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IEC338SC_RS06375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEC338SC_RS06385	COG1981	membrane
IEC338SC_RS06400	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEC338SC_RS06410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEC338SC_RS06415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEC338SC_RS06430	COG0456	acetyltransferase
IEC338SC_RS06440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IEC338SC_RS06445	COG0492	ferredoxin-NADP+ reductase activity
IEC338SC_RS06450	COG1674	ftsk spoiiie
IEC338SC_RS06455	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS06470	COG2894	cell division
IEC338SC_RS06485	COG0204	Acyl-transferase
IEC338SC_RS06490	COG2885	chlorophyll binding
IEC338SC_RS06495	COG0210	DNA helicase
IEC338SC_RS06505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEC338SC_RS06520	COG0121	glutamine amidotransferase
IEC338SC_RS06535	COG2914	Belongs to the UPF0125 (RnfH) family
IEC338SC_RS06540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEC338SC_RS06545	COG0735	belongs to the Fur family
IEC338SC_RS06580	COG0420	3'-5' exonuclease activity
IEC338SC_RS06600	COG1090	epimerase
IEC338SC_RS06615	COG2050	protein possibly involved in aromatic compounds catabolism
IEC338SC_RS06625	COG2814	Major facilitator Superfamily
IEC338SC_RS06630	COG0405	Gamma-glutamyltransferase
IEC338SC_RS06640	COG0582	viral genome integration into host DNA
IEC338SC_RS06700	COG0210	DNA helicase
IEC338SC_RS06720	COG0210	DNA helicase
IEC338SC_RS06770	COG2801	Transposase and inactivated derivatives
IEC338SC_RS06780	COG0477	Major facilitator Superfamily
IEC338SC_RS06785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEC338SC_RS06835	COG0531	amino acid
IEC338SC_RS06840	COG2040	homocysteine
IEC338SC_RS06865	COG1309	transcriptional regulator
IEC338SC_RS06870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEC338SC_RS06875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEC338SC_RS06885	COG1607	acyl-coa hydrolase
IEC338SC_RS06895	COG0523	cobalamin synthesis protein
IEC338SC_RS06905	COG4681	YaeQ
IEC338SC_RS06915	COG1649	PFAM Uncharacterised BCR, COG1649
IEC338SC_RS06915	COG0726	polysaccharide deacetylase
IEC338SC_RS06920	COG1215	transferase activity, transferring glycosyl groups
IEC338SC_RS06930	COG1024	Enoyl-CoA hydratase
IEC338SC_RS06945	COG1414	Transcriptional regulator
IEC338SC_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS06980	COG2271	Major facilitator Superfamily
IEC338SC_RS06990	COG2267	carboxylic ester hydrolase activity
IEC338SC_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS07010	COG0028	Belongs to the TPP enzyme family
IEC338SC_RS07020	COG0477	Major facilitator Superfamily
IEC338SC_RS07025	COG0242	peptide deformylase activity
IEC338SC_RS07030	COG2066	Belongs to the glutaminase family
IEC338SC_RS07035	COG2207	Transcriptional regulator
IEC338SC_RS07040	COG2223	nitrite transmembrane transporter activity
IEC338SC_RS07065	COG0306	phosphate transporter
IEC338SC_RS07080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IEC338SC_RS07100	COG4771	TonB-dependent receptor
IEC338SC_RS07125	COG4181	ATPase activity
IEC338SC_RS07130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IEC338SC_RS07155	COG0583	DNA-binding transcription factor activity
IEC338SC_RS07160	COG2267	carboxylic ester hydrolase activity
IEC338SC_RS07165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_RS07170	COG1773	rubredoxin
IEC338SC_RS07215	COG2851	Citrate transporter
IEC338SC_RS07220	COG1253	flavin adenine dinucleotide binding
IEC338SC_RS07235	COG3015	lipoprotein NlpE involved in copper resistance
IEC338SC_RS07260	COG0804	urea catabolic process
IEC338SC_RS07270	COG0830	nickel cation binding
IEC338SC_RS07290	COG0742	ribosomal rna small subunit methyltransferase
IEC338SC_RS07295	COG0768	penicillin binding
IEC338SC_RS07325	COG0714	Associated with various cellular activities
IEC338SC_RS07330	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IEC338SC_RS07335	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IEC338SC_RS07345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEC338SC_RS07350	COG2878	Part of a membrane complex involved in electron transport
IEC338SC_RS07355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEC338SC_RS07365	COG3384	dioxygenase
IEC338SC_RS07380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEC338SC_RS07415	COG0006	proline dipeptidase activity
IEC338SC_RS07420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_RS07425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_RS07435	COG0789	Transcriptional regulator
IEC338SC_RS07445	COG1279	arginine transmembrane transporter activity
IEC338SC_RS07450	COG0583	DNA-binding transcription factor activity
IEC338SC_RS07495	COG1388	LysM domain
IEC338SC_RS07495	COG0741	lytic transglycosylase activity
IEC338SC_RS07500	COG4166	transmembrane transport
IEC338SC_RS07505	COG4174	ABC transporter (Permease)
IEC338SC_RS07510	COG4239	(ABC) transporter, permease
IEC338SC_RS07515	COG4172	Belongs to the ABC transporter superfamily
IEC338SC_RS07535	COG0582	viral genome integration into host DNA
IEC338SC_RS07610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEC338SC_RS07620	COG2203	Gaf domain
IEC338SC_RS07620	COG3706	GGDEF domain
IEC338SC_RS07620	COG4251	negative regulation of phosphorylation
IEC338SC_RS07620	COG5001	Diguanylate cyclase
IEC338SC_RS07635	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_RS07635	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_RS07645	COG1309	transcriptional regulator
IEC338SC_RS07655	COG0251	oxidation-reduction process
IEC338SC_RS07665	COG0583	DNA-binding transcription factor activity
IEC338SC_RS07690	COG4269	membrane
IEC338SC_RS07745	COG1113	amino acid transport
IEC338SC_RS07755	COG0531	amino acid
IEC338SC_RS07775	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS07795	COG1113	amino acid transport
IEC338SC_RS07800	COG2831	hemolysin activation secretion protein
IEC338SC_RS07805	COG3210	domain, Protein
IEC338SC_RS07845	COG0697	spore germination
IEC338SC_RS07870	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS07880	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS07885	COG1024	Enoyl-CoA hydratase
IEC338SC_RS07890	COG2814	Major facilitator Superfamily
IEC338SC_RS07905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_RS07920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IEC338SC_RS07940	COG1944	ATP diphosphatase activity
IEC338SC_RS07970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IEC338SC_RS07985	COG0583	DNA-binding transcription factor activity
IEC338SC_RS07990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IEC338SC_RS07995	COG2072	flavoprotein involved in K transport
IEC338SC_RS08010	COG1309	transcriptional regulator
IEC338SC_RS08015	COG1741	Belongs to the pirin family
IEC338SC_RS08025	COG2252	PERMEase
IEC338SC_RS08030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IEC338SC_RS08035	COG3038	cytochrome b561
IEC338SC_RS08045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEC338SC_RS08055	COG0527	aspartate kinase activity
IEC338SC_RS08065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IEC338SC_RS08075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEC338SC_RS08090	COG0667	Aldo Keto reductase
IEC338SC_RS08100	COG1765	OsmC-like protein
IEC338SC_RS08115	COG0542	response to heat
IEC338SC_RS08150	COG2885	chlorophyll binding
IEC338SC_RS08160	COG0625	glutathione transferase activity
IEC338SC_RS08170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IEC338SC_RS08190	COG3634	alkyl hydroperoxide reductase activity
IEC338SC_RS08215	COG1643	Atp-dependent helicase
IEC338SC_RS08230	COG2814	Major facilitator Superfamily
IEC338SC_RS08235	COG3135	benzoate transporter
IEC338SC_RS08240	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS08245	COG0543	2 iron, 2 sulfur cluster binding
IEC338SC_RS08245	COG0633	Ferredoxin
IEC338SC_RS08250	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEC338SC_RS08255	COG4638	Rieske (2fe-2S)
IEC338SC_RS08260	COG0583	DNA-binding transcription factor activity
IEC338SC_RS08270	COG2871	sodium ion transport
IEC338SC_RS08350	COG1570	exodeoxyribonuclease VII activity
IEC338SC_RS08385	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS08390	COG1560	Kdo2-lipid A biosynthetic process
IEC338SC_RS08395	COG1278	Cold shock
IEC338SC_RS08415	COG2226	methyltransferase
IEC338SC_RS08435	COG2801	Transposase and inactivated derivatives
IEC338SC_RS08445	COG1309	transcriptional regulator
IEC338SC_RS08485	COG0668	transmembrane transport
IEC338SC_RS08495	COG2814	Major facilitator Superfamily
IEC338SC_RS08530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEC338SC_RS08560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IEC338SC_RS08570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IEC338SC_RS08575	COG1137	ATPase activity
IEC338SC_RS08580	COG1538	Outer membrane efflux protein
IEC338SC_RS08610	COG4122	O-methyltransferase activity
IEC338SC_RS08620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IEC338SC_RS08635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_RS08650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEC338SC_RS08655	COG0531	amino acid
IEC338SC_RS08660	COG1522	sequence-specific DNA binding
IEC338SC_RS08675	COG2207	Transcriptional regulator
IEC338SC_RS08685	COG2801	Transposase and inactivated derivatives
IEC338SC_RS08705	COG1733	regulation of RNA biosynthetic process
IEC338SC_RS08710	COG0753	catalase activity
IEC338SC_RS08715	COG3038	cytochrome b561
IEC338SC_RS08720	COG2271	Major facilitator Superfamily
IEC338SC_RS08740	COG0583	DNA-binding transcription factor activity
IEC338SC_RS08745	COG0402	S-adenosylhomocysteine deaminase activity
IEC338SC_RS08770	COG0657	acetylesterase activity
IEC338SC_RS08785	COG1309	transcriptional regulator
IEC338SC_RS08790	COG1051	belongs to the nudix hydrolase family
IEC338SC_RS08800	COG1309	transcriptional regulator
IEC338SC_RS08810	COG3209	COG3209 Rhs family protein
IEC338SC_RS08880	COG3220	belongs to the UPF0276 family
IEC338SC_RS08890	COG1595	DNA-templated transcription, initiation
IEC338SC_RS08900	COG0583	DNA-binding transcription factor activity
IEC338SC_RS08905	COG1914	H( )-stimulated, divalent metal cation uptake system
IEC338SC_RS08925	COG4770	biotin carboxylase activity
IEC338SC_RS08930	COG0038	chloride channel
IEC338SC_RS08935	COG2831	hemolysin activation secretion protein
IEC338SC_RS08940	COG3210	domain, Protein
IEC338SC_RS08955	COG2801	Transposase and inactivated derivatives
IEC338SC_RS08980	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEC338SC_RS08985	COG1063	alcohol dehydrogenase
IEC338SC_RS09000	COG0439	Biotin carboxylase
IEC338SC_RS09005	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_RS09010	COG1733	regulation of RNA biosynthetic process
IEC338SC_RS09020	COG0864	Transcriptional regulator
IEC338SC_RS09030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_RS09035	COG1116	anion transmembrane transporter activity
IEC338SC_RS09100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IEC338SC_RS09160	COG2885	chlorophyll binding
IEC338SC_RS09210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_RS09215	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IEC338SC_RS09225	COG0789	Transcriptional regulator
IEC338SC_RS09240	COG1760	l-serine dehydratase
IEC338SC_RS09245	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS09245	COG2030	dehydratase
IEC338SC_RS09250	COG3396	Phenylacetate-CoA oxygenase
IEC338SC_RS09255	COG3460	Phenylacetate-CoA oxygenase
IEC338SC_RS09260	COG3396	Phenylacetate-CoA oxygenase
IEC338SC_RS09265	COG2151	metal-sulfur cluster biosynthetic enzyme
IEC338SC_RS09270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_RS09275	COG1024	Enoyl-CoA hydratase
IEC338SC_RS09280	COG1024	Enoyl-CoA hydratase
IEC338SC_RS09285	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEC338SC_RS09290	COG0183	Belongs to the thiolase family
IEC338SC_RS09295	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IEC338SC_RS09300	COG3327	negative regulation of DNA-templated transcription, initiation
IEC338SC_RS09335	COG0406	alpha-ribazole phosphatase activity
IEC338SC_RS09365	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09375	COG1414	Transcriptional regulator
IEC338SC_RS09380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_RS09395	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS09405	COG1840	ABC-type Fe3 transport system, periplasmic component
IEC338SC_RS09410	COG3842	ATPase activity
IEC338SC_RS09425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IEC338SC_RS09430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IEC338SC_RS09435	COG2814	Major facilitator Superfamily
IEC338SC_RS09440	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS09455	COG1024	Enoyl-CoA hydratase
IEC338SC_RS09465	COG2814	Major facilitator Superfamily
IEC338SC_RS09475	COG0183	Belongs to the thiolase family
IEC338SC_RS09480	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEC338SC_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS09490	COG1024	Enoyl-CoA hydratase
IEC338SC_RS09495	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS09500	COG2814	Major facilitator Superfamily
IEC338SC_RS09505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEC338SC_RS09510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEC338SC_RS09520	COG2814	Major facilitator Superfamily
IEC338SC_RS09530	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS09545	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09555	COG4770	biotin carboxylase activity
IEC338SC_RS09560	COG1024	Enoyl-CoA hydratase
IEC338SC_RS09565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IEC338SC_RS09570	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS09575	COG1309	transcriptional regulator
IEC338SC_RS09580	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_RS09595	COG2814	Major facilitator Superfamily
IEC338SC_RS09605	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS09670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEC338SC_RS09690	COG2205	protein histidine kinase activity
IEC338SC_RS09690	COG0784	Response regulator, receiver
IEC338SC_RS09705	COG0765	amino acid transport
IEC338SC_RS09710	COG0765	amino acid transport
IEC338SC_RS09720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_RS09725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_RS09735	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS09740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEC338SC_RS09745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEC338SC_RS09750	COG1045	serine acetyltransferase
IEC338SC_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS09765	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09770	COG0625	glutathione transferase activity
IEC338SC_RS09775	COG0625	glutathione transferase activity
IEC338SC_RS09780	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09790	COG1346	cytolysis
IEC338SC_RS09810	COG2814	Major facilitator Superfamily
IEC338SC_RS09820	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IEC338SC_RS09825	COG3052	prosthetic group binding
IEC338SC_RS09845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IEC338SC_RS09865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_RS09870	COG1294	oxidase, subunit
IEC338SC_RS09875	COG1271	oxidase subunit
IEC338SC_RS09895	COG0477	Major facilitator Superfamily
IEC338SC_RS09905	COG4521	taurine ABC transporter
IEC338SC_RS09910	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IEC338SC_RS09915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEC338SC_RS09920	COG2175	clavaminate synthase activity
IEC338SC_RS09930	COG1953	Uracil, thiamine, allantoin
IEC338SC_RS09940	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IEC338SC_RS09960	COG0640	Transcriptional regulator
IEC338SC_RS09970	COG0798	PFAM Bile acid sodium symporter
IEC338SC_RS09975	COG0431	NADPH-dependent FMN reductase
IEC338SC_RS09980	COG0583	DNA-binding transcription factor activity
IEC338SC_RS09995	COG3634	alkyl hydroperoxide reductase activity
IEC338SC_RS10030	COG1301	dicarboxylic acid transport
IEC338SC_RS10035	COG0436	Aminotransferase
IEC338SC_RS10045	COG0386	Belongs to the glutathione peroxidase family
IEC338SC_RS10085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IEC338SC_RS10110	COG0012	GTP binding
IEC338SC_RS10115	COG2011	ABC-type metal ion transport system permease component
IEC338SC_RS10120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEC338SC_RS10130	COG1464	Belongs to the NlpA lipoprotein family
IEC338SC_RS10165	COG0765	amino acid transport
IEC338SC_RS10170	COG0765	amino acid transport
IEC338SC_RS10175	COG1126	abc transporter atp-binding protein
IEC338SC_RS10185	COG1522	sequence-specific DNA binding
IEC338SC_RS10200	COG1309	transcriptional regulator
IEC338SC_RS10215	COG0583	DNA-binding transcription factor activity
IEC338SC_RS10225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IEC338SC_RS10235	COG0697	spore germination
IEC338SC_RS10240	COG0583	DNA-binding transcription factor activity
IEC338SC_RS10260	COG3121	Chaperone
IEC338SC_RS10265	COG3539	Fimbrial protein
IEC338SC_RS10290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEC338SC_RS10290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IEC338SC_RS10335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEC338SC_RS10345	COG2353	YceI-like domain
IEC338SC_RS10355	COG3698	Phosphodiester glycosidase
IEC338SC_RS10370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEC338SC_RS10375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IEC338SC_RS10375	COG0506	proline dehydrogenase activity
IEC338SC_RS10375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IEC338SC_RS10385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEC338SC_RS10390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEC338SC_RS10410	COG1132	(ABC) transporter
IEC338SC_RS10415	COG3122	Protein conserved in bacteria
IEC338SC_RS10420	COG3619	membrane
IEC338SC_RS10430	COG0640	Transcriptional regulator
IEC338SC_RS10440	COG2850	peptidyl-arginine hydroxylation
IEC338SC_RS10445	COG0424	maF-like protein
IEC338SC_RS10470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IEC338SC_RS10480	COG3178	'Phosphotransferase
IEC338SC_RS10485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IEC338SC_RS10495	COG1192	Involved in chromosome partitioning
IEC338SC_RS10500	COG1475	DNA binding
IEC338SC_RS10505	COG0811	peptide transport
IEC338SC_RS10515	COG1132	(ABC) transporter
IEC338SC_RS10520	COG1663	tetraacyldisaccharide 4'-kinase activity
IEC338SC_RS10540	COG0084	hydrolase, TatD family'
IEC338SC_RS10605	COG0776	regulation of translation
IEC338SC_RS10620	COG2431	L-lysine efflux transmembrane transporter activity
IEC338SC_RS10635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IEC338SC_RS10640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IEC338SC_RS10665	COG4206	TonB-dependent receptor
IEC338SC_RS10675	COG4166	transmembrane transport
IEC338SC_RS10680	COG0339	signal peptide processing
IEC338SC_RS10685	COG0601	transmembrane transport
IEC338SC_RS10725	COG0702	epimerase
IEC338SC_RS10730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IEC338SC_RS10750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEC338SC_RS10780	COG0316	Belongs to the HesB IscA family
IEC338SC_RS10785	COG0822	iron-sulfur transferase activity
IEC338SC_RS10810	COG0776	regulation of translation
IEC338SC_RS10815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IEC338SC_RS10820	COG2207	Transcriptional regulator
IEC338SC_RS10825	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEC338SC_RS10830	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS10835	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS10850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEC338SC_RS10855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IEC338SC_RS10870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IEC338SC_RS10890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IEC338SC_RS10895	COG0730	response to heat
IEC338SC_RS10915	COG4773	Receptor
IEC338SC_RS10920	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IEC338SC_RS10980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEC338SC_RS10990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEC338SC_RS10995	COG0583	DNA-binding transcription factor activity
IEC338SC_RS11020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEC338SC_RS11030	COG0133	tryptophan synthase activity
IEC338SC_RS11050	COG3706	GGDEF domain
IEC338SC_RS11065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEC338SC_RS11070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IEC338SC_RS11075	COG0022	dehydrogenase e1 component
IEC338SC_RS11080	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEC338SC_RS11085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_RS11095	COG1063	alcohol dehydrogenase
IEC338SC_RS11100	COG3781	membrane
IEC338SC_RS11110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_RS11110	COG3453	Protein conserved in bacteria
IEC338SC_RS11120	COG0730	response to heat
IEC338SC_RS11135	COG3708	Transcriptional regulator
IEC338SC_RS11135	COG2207	Transcriptional regulator
IEC338SC_RS11145	COG0477	Major facilitator Superfamily
IEC338SC_RS11155	COG1027	Aspartate ammonia-lyase
IEC338SC_RS11170	COG0583	DNA-binding transcription factor activity
IEC338SC_RS11175	COG0583	DNA-binding transcription factor activity
IEC338SC_RS11180	COG0183	Belongs to the thiolase family
IEC338SC_RS11185	COG2031	fatty acid transporter
IEC338SC_RS11200	COG0583	DNA-binding transcription factor activity
IEC338SC_RS11250	COG2610	gluconate transmembrane transporter activity
IEC338SC_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS11260	COG2207	Transcriptional regulator
IEC338SC_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS11290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_RS11305	COG0543	2 iron, 2 sulfur cluster binding
IEC338SC_RS11305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_RS11310	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEC338SC_RS11315	COG4638	Rieske (2fe-2S)
IEC338SC_RS11325	COG0725	ABC transporter, periplasmic molybdate-binding protein
IEC338SC_RS11330	COG4149	molybdate abc transporter
IEC338SC_RS11335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IEC338SC_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS11345	COG3433	isochorismatase activity
IEC338SC_RS11345	COG1535	isochorismatase
IEC338SC_RS11390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEC338SC_RS11395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_RS11400	COG0745	RESPONSE REGULATOR receiver
IEC338SC_RS11405	COG2205	protein histidine kinase activity
IEC338SC_RS11415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEC338SC_RS11445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IEC338SC_RS11470	COG3539	Fimbrial protein
IEC338SC_RS11505	COG0583	DNA-binding transcription factor activity
IEC338SC_RS11510	COG0402	S-adenosylhomocysteine deaminase activity
IEC338SC_RS11520	COG1609	Transcriptional regulator
IEC338SC_RS11520	COG2207	Transcriptional regulator
IEC338SC_RS11530	COG1271	oxidase subunit
IEC338SC_RS11535	COG1294	oxidase, subunit
IEC338SC_RS11545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IEC338SC_RS11550	COG2814	Major facilitator Superfamily
IEC338SC_RS11560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IEC338SC_RS11570	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_RS11575	COG3118	belongs to the thioredoxin family
IEC338SC_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS11585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEC338SC_RS11605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_RS11635	COG1414	Transcriptional regulator
IEC338SC_RS11640	COG4977	sequence-specific DNA binding
IEC338SC_RS11640	COG1917	Cupin 2, conserved barrel domain protein
IEC338SC_RS11650	COG1535	isochorismatase
IEC338SC_RS11650	COG3433	isochorismatase activity
IEC338SC_RS11655	COG4628	conserved protein (DUF2132)
IEC338SC_RS11690	COG3210	domain, Protein
IEC338SC_RS11715	COG2801	Transposase and inactivated derivatives
IEC338SC_RS11805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEC338SC_RS11825	COG1120	ATPase activity
IEC338SC_RS11830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEC338SC_RS11900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IEC338SC_RS11905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IEC338SC_RS11930	COG0583	DNA-binding transcription factor activity
IEC338SC_RS11985	COG1309	transcriptional regulator
IEC338SC_RS11995	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_RS12005	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS12020	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS12025	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS12030	COG0583	DNA-binding transcription factor activity
IEC338SC_RS12035	COG1309	transcriptional regulator
IEC338SC_RS12055	COG0789	Transcriptional regulator
IEC338SC_RS12065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEC338SC_RS12075	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_RS12075	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_RS12095	COG0583	DNA-binding transcription factor activity
IEC338SC_RS12100	COG2814	Major facilitator Superfamily
IEC338SC_RS12105	COG2814	Major facilitator Superfamily
IEC338SC_RS12110	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_RS12115	COG3384	dioxygenase
IEC338SC_RS12120	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS12130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEC338SC_RS12135	COG4638	Rieske (2fe-2S)
IEC338SC_RS12140	COG0583	DNA-binding transcription factor activity
IEC338SC_RS12160	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IEC338SC_RS12165	COG3971	2-oxopent-4-enoate hydratase activity
IEC338SC_RS12175	COG0583	DNA-binding transcription factor activity
IEC338SC_RS12180	COG4948	Mandelate Racemase Muconate Lactonizing
IEC338SC_RS12185	COG4829	muconolactone delta-isomerase
IEC338SC_RS12195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEC338SC_RS12200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEC338SC_RS12205	COG0183	Belongs to the thiolase family
IEC338SC_RS12210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEC338SC_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_RS12225	COG3733	amine oxidase
IEC338SC_RS12235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_RS12245	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS12255	COG4638	Rieske (2fe-2S)
IEC338SC_RS12275	COG0154	amidase activity
IEC338SC_RS12285	COG2814	Major facilitator Superfamily
IEC338SC_RS12310	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS12315	COG0583	DNA-binding transcription factor activity
IEC338SC_RS12320	COG1414	Transcriptional regulator
IEC338SC_RS12335	COG2391	methyltransferase activity
IEC338SC_RS12345	COG4993	Dehydrogenase
IEC338SC_RS12350	COG3659	wide pore channel activity
IEC338SC_RS12355	COG3420	alginic acid biosynthetic process
IEC338SC_RS12360	COG0710	3-dehydroquinate dehydratase activity
IEC338SC_RS12365	COG3485	protocatechuate 3,4-dioxygenase
IEC338SC_RS12370	COG3485	protocatechuate 3,4-dioxygenase
IEC338SC_RS12375	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEC338SC_RS12380	COG2271	Major facilitator Superfamily
IEC338SC_RS12385	COG0596	Alpha beta hydrolase
IEC338SC_RS12390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEC338SC_RS12395	COG0183	Belongs to the thiolase family
IEC338SC_RS12400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEC338SC_RS12405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEC338SC_RS12415	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IEC338SC_RS12420	COG4773	Receptor
IEC338SC_RS12430	COG2323	membrane
IEC338SC_RS12435	COG0148	phosphopyruvate hydratase activity
IEC338SC_RS12475	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_RS12475	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_RS12490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IEC338SC_RS12500	COG0542	response to heat
IEC338SC_RS12505	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IEC338SC_RS12535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEC338SC_RS12540	COG0569	domain protein
IEC338SC_RS12545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IEC338SC_RS12560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEC338SC_RS12570	COG1585	Membrane protein implicated in regulation of membrane protease activity
IEC338SC_RS12585	COG1294	oxidase, subunit
IEC338SC_RS12590	COG4890	Cyd operon protein YbgT
IEC338SC_RS12615	COG0552	protein localization to endoplasmic reticulum
IEC338SC_RS12640	COG0516	GMP reductase activity
IEC338SC_RS12640	COG0517	IMP dehydrogenase activity
IEC338SC_RS12645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEC338SC_RS12650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IEC338SC_RS12660	COG0583	DNA-binding transcription factor activity
IEC338SC_RS12665	COG0024	Methionine aminopeptidase
IEC338SC_RS12695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEC338SC_RS12695	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEC338SC_RS12700	COG1105	Belongs to the carbohydrate kinase PfkB family
IEC338SC_RS12705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IEC338SC_RS12705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEC338SC_RS12705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEC338SC_RS12720	COG5001	Diguanylate cyclase
IEC338SC_RS12720	COG3300	MHYT domain
IEC338SC_RS12740	COG0659	secondary active sulfate transmembrane transporter activity
IEC338SC_RS12760	COG1113	amino acid transport
IEC338SC_RS12770	COG1522	sequence-specific DNA binding
IEC338SC_RS12785	COG1011	Hydrolase
IEC338SC_RS12790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IEC338SC_RS12800	COG2137	regulation of response to DNA damage stimulus
IEC338SC_RS12815	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IEC338SC_RS12835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEC338SC_RS12850	COG0575	Belongs to the CDS family
IEC338SC_RS12855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEC338SC_RS12875	COG3852	Histidine kinase
IEC338SC_RS12880	COG2204	response regulator
IEC338SC_RS12930	COG0596	Alpha beta hydrolase
IEC338SC_RS12945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEC338SC_RS12970	COG0697	spore germination
IEC338SC_RS12975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_RS12985	COG0303	'Molybdopterin
IEC338SC_RS12990	COG0521	Mo-molybdopterin cofactor biosynthetic process
IEC338SC_RS12990	COG0315	cyclic pyranopterin monophosphate synthase activity
IEC338SC_RS13005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IEC338SC_RS13010	COG0243	molybdopterin cofactor binding
IEC338SC_RS13020	COG0243	molybdopterin cofactor binding
IEC338SC_RS13025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_RS13030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_RS13030	COG2146	nitrite reductase [NAD(P)H] activity
IEC338SC_RS13045	COG1116	anion transmembrane transporter activity
IEC338SC_RS13045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_RS13060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IEC338SC_RS13070	COG4264	IucA IucC family
IEC338SC_RS13075	COG4264	IucA IucC family
IEC338SC_RS13080	COG2814	Major facilitator Superfamily
IEC338SC_RS13115	COG0511	ligase activity, forming carbon-carbon bonds
IEC338SC_RS13130	COG2814	Major facilitator Superfamily
IEC338SC_RS13150	COG3179	chitinase
IEC338SC_RS13255	COG3566	protein conserved in bacteria
IEC338SC_RS13270	COG3567	Phage-associated protein, HI1409 family
IEC338SC_RS13275	COG5410	chromosome segregation
IEC338SC_RS13435	COG0069	glutamate synthase activity
IEC338SC_RS13465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEC338SC_RS13480	COG1335	isochorismatase
IEC338SC_RS13495	COG1454	alcohol dehydrogenase
IEC338SC_RS13500	COG0824	Thioesterase
IEC338SC_RS13510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEC338SC_RS13535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IEC338SC_RS13540	COG2030	dehydratase
IEC338SC_RS13550	COG0183	Belongs to the thiolase family
IEC338SC_RS13560	COG0583	DNA-binding transcription factor activity
IEC338SC_RS13565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IEC338SC_RS13575	COG1522	sequence-specific DNA binding
IEC338SC_RS13580	COG3135	benzoate transporter
IEC338SC_RS13595	COG0589	response to stress
IEC338SC_RS13600	COG0488	(ABC) transporter
IEC338SC_RS13625	COG0583	DNA-binding transcription factor activity
IEC338SC_RS13650	COG1733	regulation of RNA biosynthetic process
IEC338SC_RS13660	COG3772	lysozyme
IEC338SC_RS13705	COG4772	TonB-dependent receptor
IEC338SC_RS13710	COG1605	Chorismate mutase
IEC338SC_RS13750	COG0308	aminopeptidase N
IEC338SC_RS13775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IEC338SC_RS13780	COG1454	alcohol dehydrogenase
IEC338SC_RS13800	COG0531	amino acid
IEC338SC_RS13805	COG4303	Ethanolamine ammonia lyase large subunit
IEC338SC_RS13810	COG4302	ethanolamine ammonia-lyase activity
IEC338SC_RS13815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IEC338SC_RS13815	COG0519	Catalyzes the synthesis of GMP from XMP
IEC338SC_RS13820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEC338SC_RS13845	COG0697	spore germination
IEC338SC_RS13850	COG1923	regulation of RNA biosynthetic process
IEC338SC_RS13860	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEC338SC_RS13865	COG0802	atpase or kinase
IEC338SC_RS13885	COG1187	pseudouridine synthase activity
IEC338SC_RS13900	COG0583	DNA-binding transcription factor activity
IEC338SC_RS13910	COG2814	Major facilitator Superfamily
IEC338SC_RS13915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEC338SC_RS13925	COG0471	metal ion transport
IEC338SC_RS13955	COG0729	surface antigen
IEC338SC_RS13960	COG0477	Major facilitator Superfamily
IEC338SC_RS13975	COG0174	glutamine synthetase
IEC338SC_RS13980	COG0745	RESPONSE REGULATOR receiver
IEC338SC_RS13985	COG2205	protein histidine kinase activity
IEC338SC_RS13995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IEC338SC_RS14000	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IEC338SC_RS14010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEC338SC_RS14025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_RS14030	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS14045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_RS14050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEC338SC_RS14055	COG2890	protein-(glutamine-N5) methyltransferase activity
IEC338SC_RS14070	COG0583	DNA-binding transcription factor activity
IEC338SC_RS14085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEC338SC_RS14095	COG3658	cytochrome
IEC338SC_RS14100	COG1215	transferase activity, transferring glycosyl groups
IEC338SC_RS14105	COG0726	polysaccharide deacetylase
IEC338SC_RS14105	COG1649	PFAM Uncharacterised BCR, COG1649
IEC338SC_RS14135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEC338SC_RS14140	COG1845	cytochrome c oxidase, subunit III
IEC338SC_RS14145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IEC338SC_RS14170	COG0305	Participates in initiation and elongation during chromosome replication
IEC338SC_RS14175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEC338SC_RS14185	COG1305	Transglutaminase-like
IEC338SC_RS14195	COG2308	Evidence 4 Homologs of previously reported genes of
IEC338SC_RS14225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IEC338SC_RS14235	COG0151	Belongs to the GarS family
IEC338SC_RS14240	COG1464	Belongs to the NlpA lipoprotein family
IEC338SC_RS14245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEC338SC_RS14250	COG2011	ABC-type metal ion transport system permease component
IEC338SC_RS14255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_RS14265	COG1301	dicarboxylic acid transport
IEC338SC_RS14295	COG1794	racemase activity, acting on amino acids and derivatives
IEC338SC_RS14310	COG0745	RESPONSE REGULATOR receiver
IEC338SC_RS14315	COG0642	Histidine kinase
IEC338SC_RS14320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IEC338SC_RS14330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IEC338SC_RS14370	COG2351	hydroxyisourate hydrolase activity
IEC338SC_RS14380	COG3008	intermembrane lipid transfer
IEC338SC_RS14380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IEC338SC_RS14385	COG2995	paraquat-inducible protein a
IEC338SC_RS14395	COG0583	DNA-binding transcription factor activity
IEC338SC_RS14400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEC338SC_RS14425	COG0475	glutathione-regulated potassium exporter activity
IEC338SC_RS14425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IEC338SC_RS14430	COG0786	glutamate:sodium symporter activity
IEC338SC_RS14435	COG3243	poly(R)-hydroxyalkanoic acid synthase
IEC338SC_RS14450	COG1278	Cold shock
IEC338SC_RS14475	COG0515	serine threonine protein kinase
IEC338SC_RS14475	COG2815	serine threonine protein kinase
IEC338SC_RS14505	COG1610	YqeY-like protein
IEC338SC_RS14510	COG4783	chaperone-mediated protein folding
IEC338SC_RS14535	COG1286	toxin biosynthetic process
IEC338SC_RS14565	COG0778	Nitroreductase
IEC338SC_RS14575	COG0513	Belongs to the DEAD box helicase family
IEC338SC_RS14595	COG2363	Small membrane protein
IEC338SC_RS14620	COG4650	regulator
IEC338SC_RS14625	COG1234	tRNA 3'-trailer cleavage
IEC338SC_RS14630	COG1690	Belongs to the RtcB family
IEC338SC_RS14650	COG2195	Cleaves the N-terminal amino acid of tripeptides
IEC338SC_RS14660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IEC338SC_RS14680	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS14685	COG1301	dicarboxylic acid transport
IEC338SC_RS14690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IEC338SC_RS14695	COG3139	Protein of unknown function (DUF1315)
IEC338SC_RS14700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEC338SC_RS14705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEC338SC_RS14715	COG0494	nUDIX hydrolase
IEC338SC_RS14725	COG0642	Histidine kinase
IEC338SC_RS14740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IEC338SC_RS14750	COG1720	tRNA m6t6A37 methyltransferase activity
IEC338SC_RS14760	COG0384	phenazine biosynthesis protein PhzF
IEC338SC_RS14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_RS14770	COG0826	peptidase U32
IEC338SC_RS14775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEC338SC_RS14785	COG4598	ABC transporter
IEC338SC_RS14790	COG4160	amino acid transport
IEC338SC_RS14795	COG4215	(ABC) transporter
IEC338SC_RS14800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_RS14810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_RS14850	COG1131	(ABC) transporter
IEC338SC_RS14855	COG0842	Transport permease protein
IEC338SC_RS14870	COG0772	Belongs to the SEDS family
IEC338SC_RS14875	COG2951	lytic endotransglycosylase activity
IEC338SC_RS14900	COG2207	Transcriptional regulator
IEC338SC_RS14915	COG0052	Belongs to the universal ribosomal protein uS2 family
IEC338SC_RS14920	COG0024	Methionine aminopeptidase
IEC338SC_RS14930	COG2223	nitrite transmembrane transporter activity
IEC338SC_RS14940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_RS14945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEC338SC_RS14950	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS14965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IEC338SC_RS14970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IEC338SC_RS14975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IEC338SC_RS14995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEC338SC_RS15000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEC338SC_RS15005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEC338SC_RS15040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IEC338SC_RS15050	COG0174	glutamine synthetase
IEC338SC_RS15065	COG0582	viral genome integration into host DNA
IEC338SC_RS15170	COG3561	AntA/AntB antirepressor
IEC338SC_RS15375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEC338SC_RS15405	COG0512	Glutamine amidotransferase of anthranilate synthase
IEC338SC_RS15420	COG2840	Smr protein MutS2
IEC338SC_RS15430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IEC338SC_RS15440	COG0302	gtp cyclohydrolase
IEC338SC_RS15460	COG3739	integral membrane protein
IEC338SC_RS15475	COG1169	isochorismate synthase
IEC338SC_RS15480	COG2977	Belongs to the P-Pant transferase superfamily
IEC338SC_RS15485	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IEC338SC_RS15490	COG1132	(ABC) transporter
IEC338SC_RS15495	COG1132	(ABC) transporter
IEC338SC_RS15505	COG1535	isochorismatase
IEC338SC_RS15505	COG3433	isochorismatase activity
IEC338SC_RS15510	COG1021	2,3-dihydroxybenzoate-AMP ligase
IEC338SC_RS15515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEC338SC_RS15525	COG4774	siderophore transport
IEC338SC_RS15530	COG4607	ABC-type enterochelin transport system periplasmic component
IEC338SC_RS15535	COG4604	ABC transporter, ATP-binding protein
IEC338SC_RS15540	COG4605	iron ion homeostasis
IEC338SC_RS15545	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEC338SC_RS15550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEC338SC_RS15565	COG1741	Belongs to the pirin family
IEC338SC_RS15575	COG2964	Protein conserved in bacteria
IEC338SC_RS15585	COG2423	ornithine cyclodeaminase activity
IEC338SC_RS15600	COG1401	restriction endodeoxyribonuclease activity
IEC338SC_RS15610	COG2879	small protein
IEC338SC_RS15615	COG1966	Carbon starvation protein
IEC338SC_RS15620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEC338SC_RS15660	COG1067	ATP-dependent peptidase activity
IEC338SC_RS15665	COG0583	DNA-binding transcription factor activity
IEC338SC_RS15690	COG1686	Belongs to the peptidase S11 family
IEC338SC_RS15695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IEC338SC_RS15730	COG0616	signal peptide processing
IEC338SC_RS15735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IEC338SC_RS15745	COG0573	inorganic phosphate transmembrane transporter activity
IEC338SC_RS15750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IEC338SC_RS15755	COG1113	amino acid transport
IEC338SC_RS15760	COG3961	Belongs to the TPP enzyme family
IEC338SC_RS15765	COG1522	sequence-specific DNA binding
IEC338SC_RS15775	COG0076	glutamate decarboxylase activity
IEC338SC_RS15780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_RS15795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_RS15830	COG0352	thiamine-phosphate diphosphorylase activity
IEC338SC_RS15855	COG0612	Peptidase, M16
IEC338SC_RS15865	COG1823	symporter activity
IEC338SC_RS15870	COG0583	DNA-binding transcription factor activity
IEC338SC_RS15875	COG0477	Major facilitator Superfamily
IEC338SC_RS15885	COG1187	pseudouridine synthase activity
IEC338SC_RS15900	COG1686	Belongs to the peptidase S11 family
IEC338SC_RS15905	COG1252	NADH dehydrogenase
IEC338SC_RS15915	COG0415	Belongs to the DNA photolyase family
IEC338SC_RS15930	COG1215	transferase activity, transferring glycosyl groups
IEC338SC_RS15960	COG2070	2-Nitropropane dioxygenase
IEC338SC_RS16305	COG2962	Rard protein
IEC338SC_RS16315	COG0556	nucleotide-excision repair
IEC338SC_RS16335	COG0436	Aminotransferase
IEC338SC_RS16360	COG4221	oxidoreductase activity
IEC338SC_RS16370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IEC338SC_RS16375	COG1381	Involved in DNA repair and RecF pathway recombination
IEC338SC_RS16385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEC338SC_RS16390	COG0571	ribonuclease III activity
IEC338SC_RS16400	COG0681	Belongs to the peptidase S26 family
IEC338SC_RS16405	COG0481	GTPase activity
IEC338SC_RS16415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEC338SC_RS16435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEC338SC_RS16440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_RS16445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IEC338SC_RS16455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IEC338SC_RS16460	COG4208	sulfate ABC transporter
IEC338SC_RS16465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IEC338SC_RS16470	COG0583	DNA-binding transcription factor activity
IEC338SC_RS16475	COG4625	pathogenesis
IEC338SC_RS16490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IEC338SC_RS16505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IEC338SC_RS16520	COG1051	belongs to the nudix hydrolase family
IEC338SC_RS16520	COG1056	cytidyltransferase-related domain
IEC338SC_RS16525	COG1024	Enoyl-CoA hydratase
IEC338SC_RS16530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEC338SC_RS16535	COG2814	Major facilitator Superfamily
IEC338SC_RS16545	COG0047	phosphoribosylformylglycinamidine synthase activity
IEC338SC_RS16545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEC338SC_RS16565	COG1473	amidohydrolase
IEC338SC_RS16570	COG0824	Thioesterase
IEC338SC_RS16590	COG0823	Involved in the tonB-independent uptake of proteins
IEC338SC_RS16610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEC338SC_RS16645	COG0628	permease
IEC338SC_RS16655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IEC338SC_RS16660	COG0596	Alpha beta hydrolase
IEC338SC_RS16665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IEC338SC_RS16665	COG0616	signal peptide processing
IEC338SC_RS16675	COG0658	competence protein
IEC338SC_RS16675	COG2333	competence protein COMEC
IEC338SC_RS16680	COG1136	(ABC) transporter
IEC338SC_RS16685	COG4591	ABC-type transport system involved in lipoprotein release permease component
IEC338SC_RS16690	COG0697	spore germination
IEC338SC_RS16715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_RS16745	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IEC338SC_RS16750	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_RS16770	COG0019	diaminopimelate decarboxylase activity
IEC338SC_RS16780	COG1113	amino acid transport
IEC338SC_RS16785	COG1115	amino acid carrier protein
IEC338SC_RS16800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IEC338SC_RS16815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IEC338SC_RS16820	COG0243	molybdopterin cofactor binding
IEC338SC_RS16825	COG1929	Belongs to the glycerate kinase type-1 family
IEC338SC_RS16840	COG0778	Nitroreductase
IEC338SC_RS16855	COG0406	alpha-ribazole phosphatase activity
IEC338SC_RS16890	COG0789	Transcriptional regulator
IEC338SC_RS16925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IEC338SC_RS16945	COG0741	lytic transglycosylase activity
IEC338SC_RS16965	COG0584	glycerophosphoryl diester phosphodiesterase
IEC338SC_RS16995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IEC338SC_RS17000	COG1597	lipid kinase activity
IEC338SC_RS17015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEC338SC_RS17020	COG0477	Major facilitator Superfamily
IEC338SC_RS17030	COG2264	protein methyltransferase activity
IEC338SC_RS17070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IEC338SC_RS17075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEC338SC_RS17105	COG0505	Belongs to the CarA family
IEC338SC_RS17120	COG1309	transcriptional regulator
IEC338SC_RS17125	COG0251	oxidation-reduction process
IEC338SC_RS17140	COG0589	response to stress
IEC338SC_RS17160	COG2843	Capsule synthesis protein
IEC338SC_RS17180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IEC338SC_RS17185	COG1053	succinate dehydrogenase
IEC338SC_RS17190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IEC338SC_RS17195	COG2009	succinate dehydrogenase
IEC338SC_RS17230	COG2921	Belongs to the UPF0250 family
IEC338SC_RS17235	COG0321	lipoyl(octanoyl) transferase activity
IEC338SC_RS17250	COG0531	amino acid
IEC338SC_RS17265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IEC338SC_RS17270	COG1648	precorrin-2 dehydrogenase activity
IEC338SC_RS17270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IEC338SC_RS17285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IEC338SC_RS17310	COG0671	phosphoesterase, PA-phosphatase related
IEC338SC_RS17315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_RS17325	COG1538	Outer membrane efflux protein
IEC338SC_RS17330	COG0393	Putative heavy-metal-binding
IEC338SC_RS17335	COG0393	Putative heavy-metal-binding
IEC338SC_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_RS17355	COG0525	valine-tRNA ligase activity
IEC338SC_RS17380	COG0583	DNA-binding transcription factor activity
IEC338SC_RS17385	COG0004	ammonium transporteR
IEC338SC_RS17395	COG0642	Histidine kinase
IEC338SC_RS17400	COG0745	RESPONSE REGULATOR receiver
IEC338SC_RS17405	COG2194	sulfuric ester hydrolase activity
IEC338SC_RS17430	COG1752	Esterase of the alpha-beta hydrolase superfamily
IEC338SC_RS17445	COG2315	Protein conserved in bacteria
IEC338SC_RS17450	COG0142	geranyltranstransferase activity
IEC338SC_RS17455	COG2828	Protein conserved in bacteria
IEC338SC_RS17460	COG1113	amino acid transport
IEC338SC_RS17465	COG2816	NAD+ diphosphatase activity
IEC338SC_RS17470	COG3046	protein related to deoxyribodipyrimidine photolyase
IEC338SC_RS17525	COG2207	Transcriptional regulator
IEC338SC_RS17550	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_RS17570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEC338SC_RS17575	COG1530	ribonuclease E activity
IEC338SC_RS17580	COG0424	maF-like protein
IEC338SC_RS17585	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IEC338SC_RS17590	COG1792	Involved in formation and maintenance of cell shape
IEC338SC_RS17595	COG1077	Cell shape determining protein MreB Mrl
IEC338SC_RS17600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEC338SC_RS17610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEC338SC_RS17640	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IEC338SC_RS17645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEC338SC_RS17650	COG1752	Esterase of the alpha-beta hydrolase superfamily
IEC338SC_RS17655	COG1115	amino acid carrier protein
IEC338SC_RS17670	COG2814	Major facilitator Superfamily
IEC338SC_RS17675	COG1289	transmembrane transporter activity
IEC338SC_RS17685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEC338SC_RS17725	COG1376	ErfK ybiS ycfS ynhG family protein
IEC338SC_RS17730	COG2832	Protein of unknown function (DUF454)
IEC338SC_RS17740	COG5510	response to toxic substance
IEC338SC_RS17765	COG0840	transmembrane signaling receptor activity
IEC338SC_RS17805	COG3422	double-strand break repair
IEC338SC_RS17810	COG2824	Alkylphosphonate utilization operon protein PhnA
IEC338SC_RS17815	COG3189	MarR family transcriptional regulator
IEC338SC_RS17825	COG0354	folic acid binding
IEC338SC_RS17830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEC338SC_RS17840	COG0679	Auxin Efflux Carrier
IEC338SC_RS17845	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_RS17850	COG4772	TonB-dependent receptor
IEC338SC_RS17855	COG2094	Belongs to the DNA glycosylase MPG family
IEC338SC_RS17870	COG4580	involved in the transport of maltose and maltodextrins
IEC338SC_RS17885	COG1217	gtp-binding protein TYPA
IEC338SC_RS17890	COG2233	PERMEase
IEC338SC_RS17900	COG0833	amino acid
IEC338SC_RS17905	COG1690	Belongs to the RtcB family
IEC338SC_RS17910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IEC338SC_RS17910	COG2885	chlorophyll binding
IEC338SC_RS17920	COG0183	Belongs to the thiolase family
IEC338SC_RS17940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_RS17960	COG2207	Transcriptional regulator
IEC338SC_RS17965	COG0183	Belongs to the thiolase family
IEC338SC_RS17985	COG2153	protein acetylation
IEC338SC_RS17995	COG1272	protein, Hemolysin III
IEC338SC_RS18000	COG0477	Major facilitator Superfamily
IEC338SC_RS18015	COG0450	alkyl hydroperoxide reductase
IEC338SC_RS18035	COG0285	dihydrofolate synthase activity
IEC338SC_RS18085	COG2096	Adenosyltransferase
IEC338SC_RS18105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IEC338SC_RS18115	COG0745	RESPONSE REGULATOR receiver
IEC338SC_RS18120	COG2205	protein histidine kinase activity
IEC338SC_RS18130	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS18135	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS18140	COG0583	DNA-binding transcription factor activity
IEC338SC_RS18145	COG0625	glutathione transferase activity
IEC338SC_RS18205	COG0438	transferase activity, transferring glycosyl groups
IEC338SC_RS18210	COG0463	Glycosyl transferase, family 2
IEC338SC_RS18215	COG0726	polysaccharide deacetylase
IEC338SC_RS18235	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IEC338SC_RS18240	COG2198	Histidine kinase
IEC338SC_RS18240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_RS18240	COG2205	protein histidine kinase activity
IEC338SC_RS18240	COG0784	Response regulator, receiver
IEC338SC_RS18290	COG1862	Preprotein translocase
IEC338SC_RS18300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEC338SC_RS18305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEC338SC_RS18315	COG3781	membrane
IEC338SC_RS18330	COG2350	Protein conserved in bacteria
IEC338SC_RS18365	COG1607	acyl-coa hydrolase
IEC338SC_RS18390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_RS18430	COG2199	diguanylate cyclase activity
IEC338SC_RS18435	COG2885	chlorophyll binding
IEC338SC_RS18435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IEC338SC_RS18440	COG1408	metallophosphoesterase
IEC338SC_RS18445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEC338SC_RS18455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEC338SC_RS18475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IEC338SC_RS18480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IEC338SC_RS18485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IEC338SC_RS18490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEC338SC_RS18495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IEC338SC_RS18505	COG2969	positive regulation of protein catabolic process
IEC338SC_RS18525	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS18530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IEC338SC_RS18545	COG1309	transcriptional regulator
IEC338SC_RS18550	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_RS18590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEC338SC_RS18595	COG0657	acetylesterase activity
IEC338SC_RS18615	COG0583	DNA-binding transcription factor activity
IEC338SC_RS18645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEC338SC_RS18645	COG5549	protein import
IEC338SC_RS18655	COG2951	lytic endotransglycosylase activity
IEC338SC_RS18660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEC338SC_RS18680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IEC338SC_RS18690	COG0671	phosphoesterase, PA-phosphatase related
IEC338SC_RS18695	COG0861	Integral membrane protein TerC family
IEC338SC_RS18705	COG0754	glutathionylspermidine amidase activity
IEC338SC_RS18715	COG0402	S-adenosylhomocysteine deaminase activity
IEC338SC_RS18730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEC338SC_RS18735	COG1230	cation diffusion facilitator family transporter
IEC338SC_RS18750	COG0706	membrane insertase activity
IEC338SC_RS18800	COG0187	DNA topoisomerase II activity