locus-tag	class	description
HRJ47_RS00010	COG0592	DNA-directed DNA polymerase activity
HRJ47_RS00020	COG0187	DNA topoisomerase II activity
HRJ47_RS00030	COG0586	Pfam SNARE associated Golgi protein
HRJ47_RS00035	COG0488	(ABC) transporter
HRJ47_RS00060	COG0596	Alpha beta hydrolase
HRJ47_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HRJ47_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HRJ47_RS00100	COG0625	glutathione transferase activity
HRJ47_RS00110	COG0733	neurotransmitter:sodium symporter activity
HRJ47_RS00150	COG2233	PERMEase
HRJ47_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS00200	COG2814	Major facilitator Superfamily
HRJ47_RS00205	COG0656	L-ascorbic acid biosynthetic process
HRJ47_RS00210	COG0583	DNA-binding transcription factor activity
HRJ47_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ47_RS00230	COG1064	alcohol dehydrogenase
HRJ47_RS00235	COG2818	Glycosylase
HRJ47_RS00250	COG1194	a g-specific adenine glycosylase
HRJ47_RS00265	COG5487	UPF0391 membrane protein
HRJ47_RS00270	COG2983	Belongs to the UPF0260 family
HRJ47_RS00275	COG2133	pyrroloquinoline quinone binding
HRJ47_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HRJ47_RS00285	COG2116	formate transmembrane transporter activity
HRJ47_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRJ47_RS00310	COG1335	isochorismatase
HRJ47_RS00315	COG0385	Bile acid
HRJ47_RS00320	COG0534	Mate efflux family protein
HRJ47_RS00325	COG1683	Conserved Protein
HRJ47_RS00340	COG0346	lactoylglutathione lyase activity
HRJ47_RS00345	COG0625	glutathione transferase activity
HRJ47_RS00355	COG1113	amino acid transport
HRJ47_RS00365	COG0523	cobalamin synthesis protein
HRJ47_RS00375	COG2188	Transcriptional regulator
HRJ47_RS00405	COG0010	Belongs to the arginase family
HRJ47_RS00415	COG0546	phosphoglycolate phosphatase activity
HRJ47_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HRJ47_RS00425	COG1280	lysine exporter protein (LysE YggA)
HRJ47_RS00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HRJ47_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HRJ47_RS00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HRJ47_RS00545	COG0534	Mate efflux family protein
HRJ47_RS00550	COG0436	Aminotransferase
HRJ47_RS00555	COG2733	membrane
HRJ47_RS00570	COG2918	glutathione biosynthetic process
HRJ47_RS00620	COG3150	esterase
HRJ47_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HRJ47_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ47_RS00650	COG2233	PERMEase
HRJ47_RS00655	COG2351	hydroxyisourate hydrolase activity
HRJ47_RS00690	COG3706	GGDEF domain
HRJ47_RS00705	COG1393	Belongs to the ArsC family
HRJ47_RS00710	COG0708	Exodeoxyribonuclease III
HRJ47_RS00735	COG0189	ligase activity
HRJ47_RS00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HRJ47_RS00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HRJ47_RS00780	COG4942	peptidase
HRJ47_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ47_RS00800	COG2119	membrane
HRJ47_RS00805	COG4774	siderophore transport
HRJ47_RS00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HRJ47_RS00810	COG0426	domain, Protein
HRJ47_RS00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HRJ47_RS00860	COG1902	pentaerythritol trinitrate reductase activity
HRJ47_RS00865	COG1519	Transferase
HRJ47_RS00870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HRJ47_RS00875	COG0668	transmembrane transport
HRJ47_RS00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRJ47_RS00890	COG1335	isochorismatase
HRJ47_RS00895	COG1522	sequence-specific DNA binding
HRJ47_RS00920	COG0784	Response regulator, receiver
HRJ47_RS00920	COG2198	Histidine kinase
HRJ47_RS00920	COG2205	protein histidine kinase activity
HRJ47_RS00925	COG3162	membrane
HRJ47_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRJ47_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HRJ47_RS00960	COG1309	transcriptional regulator
HRJ47_RS00980	COG4221	oxidoreductase activity
HRJ47_RS00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HRJ47_RS00990	COG0352	thiamine-phosphate diphosphorylase activity
HRJ47_RS00990	COG0351	phosphomethylpyrimidine kinase
HRJ47_RS01000	COG2814	Major facilitator Superfamily
HRJ47_RS01015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HRJ47_RS01025	COG1113	amino acid transport
HRJ47_RS01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HRJ47_RS01040	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS01050	COG1335	isochorismatase
HRJ47_RS01105	COG2814	Major facilitator Superfamily
HRJ47_RS01110	COG0583	DNA-binding transcription factor activity
HRJ47_RS01135	COG0667	Aldo Keto reductase
HRJ47_RS01170	COG1733	regulation of RNA biosynthetic process
HRJ47_RS01175	COG2249	NAD(P)H dehydrogenase (quinone) activity
HRJ47_RS01185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HRJ47_RS01190	COG2207	Transcriptional regulator
HRJ47_RS01250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HRJ47_RS01265	COG2329	Antibiotic biosynthesis monooxygenase
HRJ47_RS01280	COG1132	(ABC) transporter
HRJ47_RS01300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HRJ47_RS01330	COG0427	acetyl-CoA hydrolase
HRJ47_RS01355	COG0659	secondary active sulfate transmembrane transporter activity
HRJ47_RS01360	COG4221	oxidoreductase activity
HRJ47_RS01365	COG2873	o-acetylhomoserine
HRJ47_RS01370	COG0488	(ABC) transporter
HRJ47_RS01450	COG0833	amino acid
HRJ47_RS01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HRJ47_RS01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HRJ47_RS01515	COG2226	methyltransferase
HRJ47_RS01565	COG0067	glutamate synthase
HRJ47_RS01565	COG0070	glutamate synthase
HRJ47_RS01565	COG0069	glutamate synthase activity
HRJ47_RS01570	COG0493	'glutamate synthase
HRJ47_RS01580	COG1704	LemA family
HRJ47_RS01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HRJ47_RS01600	COG3307	-O-antigen
HRJ47_RS01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HRJ47_RS01640	COG0194	GDP metabolic process
HRJ47_RS01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HRJ47_RS01700	COG0335	large ribosomal subunit rRNA binding
HRJ47_RS01710	COG5380	lipid catabolic process
HRJ47_RS01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HRJ47_RS01730	COG5006	permease, DMT superfamily
HRJ47_RS01735	COG5006	permease, DMT superfamily
HRJ47_RS01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HRJ47_RS01745	COG0277	FAD linked oxidase domain protein
HRJ47_RS01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HRJ47_RS01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HRJ47_RS01775	COG1289	transmembrane transporter activity
HRJ47_RS01785	COG0628	permease
HRJ47_RS01790	COG1192	Involved in chromosome partitioning
HRJ47_RS01820	COG0833	amino acid
HRJ47_RS01825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRJ47_RS01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HRJ47_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS01880	COG0583	DNA-binding transcription factor activity
HRJ47_RS01905	COG0752	glycyl-tRNA synthetase alpha subunit
HRJ47_RS01930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HRJ47_RS01930	COG0517	IMP dehydrogenase activity
HRJ47_RS01930	COG0617	tRNA 3'-terminal CCA addition
HRJ47_RS01935	COG1983	PspC domain protein
HRJ47_RS01945	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS01960	COG0408	coproporphyrinogen oxidase activity
HRJ47_RS01980	COG0513	Belongs to the DEAD box helicase family
HRJ47_RS01990	COG1127	ABC transporter
HRJ47_RS01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HRJ47_RS02005	COG2854	intermembrane phospholipid transfer
HRJ47_RS02015	COG0598	Magnesium transport protein CorA
HRJ47_RS02025	COG0494	nUDIX hydrolase
HRJ47_RS02030	COG1040	competence protein
HRJ47_RS02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HRJ47_RS02055	COG1946	Acyl-CoA thioesterase
HRJ47_RS02060	COG1301	dicarboxylic acid transport
HRJ47_RS02075	COG1959	2 iron, 2 sulfur cluster binding
HRJ47_RS02080	COG1017	nitric oxide dioxygenase activity
HRJ47_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRJ47_RS02090	COG0433	COG0433 Predicted ATPase
HRJ47_RS02095	COG0626	cystathionine gamma-synthase activity
HRJ47_RS02110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HRJ47_RS02115	COG0088	Forms part of the polypeptide exit tunnel
HRJ47_RS02250	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HRJ47_RS02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HRJ47_RS02290	COG0339	signal peptide processing
HRJ47_RS02295	COG0557	exoribonuclease II activity
HRJ47_RS02345	COG0179	Fumarylacetoacetate (FAA) hydrolase
HRJ47_RS02350	COG1295	ribonuclease BN
HRJ47_RS02385	COG1702	phosphate starvation-inducible protein PhoH
HRJ47_RS02395	COG0741	lytic transglycosylase activity
HRJ47_RS02395	COG1196	nuclear chromosome segregation
HRJ47_RS02395	COG0739	heme binding
HRJ47_RS02425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HRJ47_RS02430	COG1183	phosphatidylcholine synthase activity
HRJ47_RS02475	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRJ47_RS02485	COG1309	transcriptional regulator
HRJ47_RS02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRJ47_RS02505	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS02545	COG2969	positive regulation of protein catabolic process
HRJ47_RS02555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HRJ47_RS02560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HRJ47_RS02565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HRJ47_RS02570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HRJ47_RS02575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HRJ47_RS02595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HRJ47_RS02605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRJ47_RS02610	COG1408	metallophosphoesterase
HRJ47_RS02615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HRJ47_RS02615	COG2885	chlorophyll binding
HRJ47_RS02620	COG2199	diguanylate cyclase activity
HRJ47_RS02660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ47_RS02685	COG1607	acyl-coa hydrolase
HRJ47_RS02720	COG2350	Protein conserved in bacteria
HRJ47_RS02735	COG3781	membrane
HRJ47_RS02745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HRJ47_RS02750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRJ47_RS02760	COG1862	Preprotein translocase
HRJ47_RS02790	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HRJ47_RS02810	COG0726	polysaccharide deacetylase
HRJ47_RS02815	COG0463	Glycosyl transferase, family 2
HRJ47_RS02820	COG0438	transferase activity, transferring glycosyl groups
HRJ47_RS02885	COG0625	glutathione transferase activity
HRJ47_RS02890	COG0583	DNA-binding transcription factor activity
HRJ47_RS02895	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS02900	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS02910	COG2205	protein histidine kinase activity
HRJ47_RS02915	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS02925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HRJ47_RS02945	COG2096	Adenosyltransferase
HRJ47_RS02950	COG4206	TonB-dependent receptor
HRJ47_RS02995	COG0285	dihydrofolate synthase activity
HRJ47_RS03015	COG0450	alkyl hydroperoxide reductase
HRJ47_RS03030	COG0477	Major facilitator Superfamily
HRJ47_RS03035	COG1272	protein, Hemolysin III
HRJ47_RS03055	COG2153	protein acetylation
HRJ47_RS03075	COG0183	Belongs to the thiolase family
HRJ47_RS03080	COG2207	Transcriptional regulator
HRJ47_RS03100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ47_RS03120	COG0183	Belongs to the thiolase family
HRJ47_RS03130	COG2885	chlorophyll binding
HRJ47_RS03130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HRJ47_RS03140	COG1690	Belongs to the RtcB family
HRJ47_RS03145	COG0833	amino acid
HRJ47_RS03155	COG2233	PERMEase
HRJ47_RS03160	COG1217	gtp-binding protein TYPA
HRJ47_RS03190	COG2094	Belongs to the DNA glycosylase MPG family
HRJ47_RS03195	COG4772	TonB-dependent receptor
HRJ47_RS03200	COG1902	pentaerythritol trinitrate reductase activity
HRJ47_RS03205	COG0679	Auxin Efflux Carrier
HRJ47_RS03215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HRJ47_RS03220	COG0354	folic acid binding
HRJ47_RS03235	COG3189	MarR family transcriptional regulator
HRJ47_RS03240	COG2824	Alkylphosphonate utilization operon protein PhnA
HRJ47_RS03245	COG3422	double-strand break repair
HRJ47_RS03285	COG0840	transmembrane signaling receptor activity
HRJ47_RS03310	COG5510	response to toxic substance
HRJ47_RS03320	COG2832	Protein of unknown function (DUF454)
HRJ47_RS03325	COG1376	ErfK ybiS ycfS ynhG family protein
HRJ47_RS03365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HRJ47_RS03375	COG1289	transmembrane transporter activity
HRJ47_RS03380	COG2814	Major facilitator Superfamily
HRJ47_RS03400	COG1115	amino acid carrier protein
HRJ47_RS03405	COG1752	Esterase of the alpha-beta hydrolase superfamily
HRJ47_RS03410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HRJ47_RS03415	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HRJ47_RS03420	COG3590	peptidase
HRJ47_RS03445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HRJ47_RS03455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HRJ47_RS03460	COG1077	Cell shape determining protein MreB Mrl
HRJ47_RS03465	COG1792	Involved in formation and maintenance of cell shape
HRJ47_RS03470	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HRJ47_RS03475	COG0424	maF-like protein
HRJ47_RS03480	COG1530	ribonuclease E activity
HRJ47_RS03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ47_RS03510	COG2249	NAD(P)H dehydrogenase (quinone) activity
HRJ47_RS03535	COG2207	Transcriptional regulator
HRJ47_RS03560	COG1113	amino acid transport
HRJ47_RS03565	COG2828	Protein conserved in bacteria
HRJ47_RS03570	COG0142	geranyltranstransferase activity
HRJ47_RS03575	COG2315	Protein conserved in bacteria
HRJ47_RS03590	COG1752	Esterase of the alpha-beta hydrolase superfamily
HRJ47_RS03615	COG2194	sulfuric ester hydrolase activity
HRJ47_RS03620	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS03625	COG0642	Histidine kinase
HRJ47_RS03635	COG0004	ammonium transporteR
HRJ47_RS03640	COG0583	DNA-binding transcription factor activity
HRJ47_RS03665	COG0525	valine-tRNA ligase activity
HRJ47_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS03685	COG0393	Putative heavy-metal-binding
HRJ47_RS03690	COG0393	Putative heavy-metal-binding
HRJ47_RS03695	COG1538	Outer membrane efflux protein
HRJ47_RS03705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS03710	COG0671	phosphoesterase, PA-phosphatase related
HRJ47_RS03735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HRJ47_RS03750	COG1648	precorrin-2 dehydrogenase activity
HRJ47_RS03750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HRJ47_RS03755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HRJ47_RS03770	COG0531	amino acid
HRJ47_RS03785	COG0321	lipoyl(octanoyl) transferase activity
HRJ47_RS03790	COG2921	Belongs to the UPF0250 family
HRJ47_RS03835	COG2009	succinate dehydrogenase
HRJ47_RS03840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HRJ47_RS03845	COG1053	succinate dehydrogenase
HRJ47_RS03850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HRJ47_RS03875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ47_RS03895	COG2354	Protein conserved in bacteria
HRJ47_RS03900	COG2321	neutral zinc metallopeptidase
HRJ47_RS03920	COG2843	Capsule synthesis protein
HRJ47_RS03940	COG0589	response to stress
HRJ47_RS03960	COG1309	transcriptional regulator
HRJ47_RS03975	COG0505	Belongs to the CarA family
HRJ47_RS04005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HRJ47_RS04010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HRJ47_RS04060	COG0477	Major facilitator Superfamily
HRJ47_RS04065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HRJ47_RS04080	COG1597	lipid kinase activity
HRJ47_RS04085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HRJ47_RS04110	COG0584	glycerophosphoryl diester phosphodiesterase
HRJ47_RS04130	COG0741	lytic transglycosylase activity
HRJ47_RS04150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HRJ47_RS04160	COG0582	viral genome integration into host DNA
HRJ47_RS04225	COG3152	Membrane
HRJ47_RS04315	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HRJ47_RS04315	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HRJ47_RS04345	COG0583	DNA-binding transcription factor activity
HRJ47_RS04365	COG0406	alpha-ribazole phosphatase activity
HRJ47_RS04385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS04395	COG0778	Nitroreductase
HRJ47_RS04410	COG1929	Belongs to the glycerate kinase type-1 family
HRJ47_RS04415	COG0243	molybdopterin cofactor binding
HRJ47_RS04420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HRJ47_RS04425	COG3339	Conserved Protein
HRJ47_RS04435	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HRJ47_RS04450	COG1115	amino acid carrier protein
HRJ47_RS04455	COG1113	amino acid transport
HRJ47_RS04465	COG0019	diaminopimelate decarboxylase activity
HRJ47_RS04475	COG1280	lysine exporter protein (LysE YggA)
HRJ47_RS04480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HRJ47_RS04510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS04540	COG4591	ABC-type transport system involved in lipoprotein release permease component
HRJ47_RS04545	COG1136	(ABC) transporter
HRJ47_RS04550	COG2333	competence protein COMEC
HRJ47_RS04550	COG0658	competence protein
HRJ47_RS04560	COG0616	signal peptide processing
HRJ47_RS04560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HRJ47_RS04565	COG0596	Alpha beta hydrolase
HRJ47_RS04570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HRJ47_RS04580	COG0628	permease
HRJ47_RS04615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRJ47_RS04635	COG0823	Involved in the tonB-independent uptake of proteins
HRJ47_RS04655	COG0824	Thioesterase
HRJ47_RS04660	COG1473	amidohydrolase
HRJ47_RS04680	COG0047	phosphoribosylformylglycinamidine synthase activity
HRJ47_RS04680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HRJ47_RS04685	COG2814	Major facilitator Superfamily
HRJ47_RS04695	COG1024	Enoyl-CoA hydratase
HRJ47_RS04700	COG1056	cytidyltransferase-related domain
HRJ47_RS04700	COG1051	belongs to the nudix hydrolase family
HRJ47_RS04715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRJ47_RS04730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HRJ47_RS04745	COG4625	pathogenesis
HRJ47_RS04750	COG0583	DNA-binding transcription factor activity
HRJ47_RS04755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HRJ47_RS04760	COG4208	sulfate ABC transporter
HRJ47_RS04765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HRJ47_RS04775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HRJ47_RS04780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HRJ47_RS04785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HRJ47_RS04805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRJ47_RS04815	COG0481	GTPase activity
HRJ47_RS04820	COG0681	Belongs to the peptidase S26 family
HRJ47_RS04830	COG0571	ribonuclease III activity
HRJ47_RS04835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HRJ47_RS04845	COG1381	Involved in DNA repair and RecF pathway recombination
HRJ47_RS04850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HRJ47_RS04860	COG4221	oxidoreductase activity
HRJ47_RS04890	COG0436	Aminotransferase
HRJ47_RS04910	COG0556	nucleotide-excision repair
HRJ47_RS04920	COG2962	Rard protein
HRJ47_RS04965	COG2070	2-Nitropropane dioxygenase
HRJ47_RS04980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HRJ47_RS04995	COG1215	transferase activity, transferring glycosyl groups
HRJ47_RS05010	COG0415	Belongs to the DNA photolyase family
HRJ47_RS05020	COG1252	NADH dehydrogenase
HRJ47_RS05025	COG1686	Belongs to the peptidase S11 family
HRJ47_RS05040	COG1187	pseudouridine synthase activity
HRJ47_RS05055	COG0477	Major facilitator Superfamily
HRJ47_RS05060	COG0583	DNA-binding transcription factor activity
HRJ47_RS05065	COG1823	symporter activity
HRJ47_RS05075	COG0612	Peptidase, M16
HRJ47_RS05100	COG0352	thiamine-phosphate diphosphorylase activity
HRJ47_RS05135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRJ47_RS05150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HRJ47_RS05155	COG0076	glutamate decarboxylase activity
HRJ47_RS05165	COG1522	sequence-specific DNA binding
HRJ47_RS05170	COG3961	Belongs to the TPP enzyme family
HRJ47_RS05175	COG1113	amino acid transport
HRJ47_RS05180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HRJ47_RS05185	COG0573	inorganic phosphate transmembrane transporter activity
HRJ47_RS05195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HRJ47_RS05200	COG0616	signal peptide processing
HRJ47_RS05235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HRJ47_RS05240	COG1686	Belongs to the peptidase S11 family
HRJ47_RS05265	COG0583	DNA-binding transcription factor activity
HRJ47_RS05270	COG1067	ATP-dependent peptidase activity
HRJ47_RS05310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HRJ47_RS05315	COG1966	Carbon starvation protein
HRJ47_RS05320	COG2879	small protein
HRJ47_RS05330	COG0583	DNA-binding transcription factor activity
HRJ47_RS05335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HRJ47_RS05345	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS05350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ47_RS05355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HRJ47_RS05355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HRJ47_RS05410	COG1741	Belongs to the pirin family
HRJ47_RS05430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ47_RS05435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ47_RS05440	COG4605	iron ion homeostasis
HRJ47_RS05445	COG4604	ABC transporter, ATP-binding protein
HRJ47_RS05450	COG4607	ABC-type enterochelin transport system periplasmic component
HRJ47_RS05455	COG4774	siderophore transport
HRJ47_RS05465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ47_RS05470	COG1021	2,3-dihydroxybenzoate-AMP ligase
HRJ47_RS05475	COG3433	isochorismatase activity
HRJ47_RS05475	COG1535	isochorismatase
HRJ47_RS05485	COG1132	(ABC) transporter
HRJ47_RS05490	COG1132	(ABC) transporter
HRJ47_RS05495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HRJ47_RS05500	COG2977	Belongs to the P-Pant transferase superfamily
HRJ47_RS05505	COG1169	isochorismate synthase
HRJ47_RS05525	COG3739	integral membrane protein
HRJ47_RS05545	COG0302	gtp cyclohydrolase
HRJ47_RS05555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HRJ47_RS05580	COG0512	Glutamine amidotransferase of anthranilate synthase
HRJ47_RS05820	COG3561	AntA/AntB antirepressor
HRJ47_RS05960	COG0582	viral genome integration into host DNA
HRJ47_RS05975	COG0174	glutamine synthetase
HRJ47_RS05985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HRJ47_RS06020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HRJ47_RS06025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HRJ47_RS06030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRJ47_RS06050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HRJ47_RS06055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HRJ47_RS06060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HRJ47_RS06075	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS06080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HRJ47_RS06085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ47_RS06095	COG2223	nitrite transmembrane transporter activity
HRJ47_RS06110	COG0024	Methionine aminopeptidase
HRJ47_RS06115	COG0052	Belongs to the universal ribosomal protein uS2 family
HRJ47_RS06130	COG2207	Transcriptional regulator
HRJ47_RS06155	COG2951	lytic endotransglycosylase activity
HRJ47_RS06160	COG0772	Belongs to the SEDS family
HRJ47_RS06175	COG0842	Transport permease protein
HRJ47_RS06180	COG1131	(ABC) transporter
HRJ47_RS06185	COG0582	viral genome integration into host DNA
HRJ47_RS06380	COG3728	DNA packaging
HRJ47_RS06590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS06600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ47_RS06605	COG4215	(ABC) transporter
HRJ47_RS06610	COG4160	amino acid transport
HRJ47_RS06615	COG4598	ABC transporter
HRJ47_RS06625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HRJ47_RS06630	COG0826	peptidase U32
HRJ47_RS06635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ47_RS06640	COG0384	phenazine biosynthesis protein PhzF
HRJ47_RS06650	COG1720	tRNA m6t6A37 methyltransferase activity
HRJ47_RS06660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HRJ47_RS06675	COG0642	Histidine kinase
HRJ47_RS06685	COG0494	nUDIX hydrolase
HRJ47_RS06695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HRJ47_RS06700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HRJ47_RS06705	COG3139	Protein of unknown function (DUF1315)
HRJ47_RS06715	COG1301	dicarboxylic acid transport
HRJ47_RS06720	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS06740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HRJ47_RS06750	COG2195	Cleaves the N-terminal amino acid of tripeptides
HRJ47_RS06770	COG1690	Belongs to the RtcB family
HRJ47_RS06775	COG1234	tRNA 3'-trailer cleavage
HRJ47_RS06780	COG4650	regulator
HRJ47_RS06810	COG2363	Small membrane protein
HRJ47_RS06830	COG0513	Belongs to the DEAD box helicase family
HRJ47_RS06840	COG0778	Nitroreductase
HRJ47_RS06870	COG1286	toxin biosynthetic process
HRJ47_RS06895	COG4783	chaperone-mediated protein folding
HRJ47_RS06900	COG1610	YqeY-like protein
HRJ47_RS06930	COG2815	serine threonine protein kinase
HRJ47_RS06930	COG0515	serine threonine protein kinase
HRJ47_RS06955	COG1278	Cold shock
HRJ47_RS06970	COG3243	poly(R)-hydroxyalkanoic acid synthase
HRJ47_RS06975	COG0786	glutamate:sodium symporter activity
HRJ47_RS06980	COG0475	glutathione-regulated potassium exporter activity
HRJ47_RS06980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HRJ47_RS06990	COG1309	transcriptional regulator
HRJ47_RS07000	COG2985	domain, Protein
HRJ47_RS07010	COG2995	paraquat-inducible protein a
HRJ47_RS07015	COG3008	intermembrane lipid transfer
HRJ47_RS07015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HRJ47_RS07025	COG2351	hydroxyisourate hydrolase activity
HRJ47_RS07065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HRJ47_RS07075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HRJ47_RS07080	COG0642	Histidine kinase
HRJ47_RS07085	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS07100	COG1794	racemase activity, acting on amino acids and derivatives
HRJ47_RS07120	COG2814	Major facilitator Superfamily
HRJ47_RS07145	COG1301	dicarboxylic acid transport
HRJ47_RS07155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ47_RS07160	COG2011	ABC-type metal ion transport system permease component
HRJ47_RS07165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HRJ47_RS07175	COG0151	Belongs to the GarS family
HRJ47_RS07185	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HRJ47_RS07215	COG2308	Evidence 4 Homologs of previously reported genes of
HRJ47_RS07225	COG1305	Transglutaminase-like
HRJ47_RS07235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HRJ47_RS07240	COG0305	Participates in initiation and elongation during chromosome replication
HRJ47_RS07265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HRJ47_RS07275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HRJ47_RS07305	COG1649	PFAM Uncharacterised BCR, COG1649
HRJ47_RS07305	COG0726	polysaccharide deacetylase
HRJ47_RS07310	COG1215	transferase activity, transferring glycosyl groups
HRJ47_RS07315	COG3658	cytochrome
HRJ47_RS07325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HRJ47_RS07340	COG0583	DNA-binding transcription factor activity
HRJ47_RS07355	COG2890	protein-(glutamine-N5) methyltransferase activity
HRJ47_RS07360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HRJ47_RS07365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HRJ47_RS07380	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS07385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HRJ47_RS07400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HRJ47_RS07410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HRJ47_RS07415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HRJ47_RS07425	COG2205	protein histidine kinase activity
HRJ47_RS07430	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS07435	COG0174	glutamine synthetase
HRJ47_RS07450	COG0477	Major facilitator Superfamily
HRJ47_RS07455	COG0729	surface antigen
HRJ47_RS07485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HRJ47_RS07490	COG2814	Major facilitator Superfamily
HRJ47_RS07500	COG0583	DNA-binding transcription factor activity
HRJ47_RS07535	COG0564	pseudouridine synthase activity
HRJ47_RS07540	COG0802	atpase or kinase
HRJ47_RS07545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HRJ47_RS07555	COG1923	regulation of RNA biosynthetic process
HRJ47_RS07560	COG0697	spore germination
HRJ47_RS07585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HRJ47_RS07590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HRJ47_RS07590	COG0519	Catalyzes the synthesis of GMP from XMP
HRJ47_RS07595	COG4302	ethanolamine ammonia-lyase activity
HRJ47_RS07600	COG4303	Ethanolamine ammonia lyase large subunit
HRJ47_RS07605	COG0531	amino acid
HRJ47_RS07625	COG1454	alcohol dehydrogenase
HRJ47_RS07630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HRJ47_RS07655	COG0308	aminopeptidase N
HRJ47_RS07695	COG1605	Chorismate mutase
HRJ47_RS07710	COG4772	TonB-dependent receptor
HRJ47_RS07750	COG3772	lysozyme
HRJ47_RS07775	COG0583	DNA-binding transcription factor activity
HRJ47_RS07810	COG0488	(ABC) transporter
HRJ47_RS07815	COG0589	response to stress
HRJ47_RS07835	COG3135	benzoate transporter
HRJ47_RS07840	COG1522	sequence-specific DNA binding
HRJ47_RS07850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HRJ47_RS07855	COG0583	DNA-binding transcription factor activity
HRJ47_RS07865	COG0183	Belongs to the thiolase family
HRJ47_RS07875	COG2030	dehydratase
HRJ47_RS07880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HRJ47_RS07905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HRJ47_RS07920	COG0824	Thioesterase
HRJ47_RS07925	COG1454	alcohol dehydrogenase
HRJ47_RS07940	COG1335	isochorismatase
HRJ47_RS07955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HRJ47_RS07985	COG0069	glutamate synthase activity
HRJ47_RS08015	COG2814	Major facilitator Superfamily
HRJ47_RS08030	COG0511	ligase activity, forming carbon-carbon bonds
HRJ47_RS08055	COG4264	IucA IucC family
HRJ47_RS08065	COG4264	IucA IucC family
HRJ47_RS08070	COG2423	ornithine cyclodeaminase activity
HRJ47_RS08075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ47_RS08085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HRJ47_RS08085	COG1116	anion transmembrane transporter activity
HRJ47_RS08100	COG2146	nitrite reductase [NAD(P)H] activity
HRJ47_RS08100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ47_RS08105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ47_RS08110	COG0243	molybdopterin cofactor binding
HRJ47_RS08120	COG0243	molybdopterin cofactor binding
HRJ47_RS08125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HRJ47_RS08140	COG0521	Mo-molybdopterin cofactor biosynthetic process
HRJ47_RS08140	COG0315	cyclic pyranopterin monophosphate synthase activity
HRJ47_RS08145	COG0303	'Molybdopterin
HRJ47_RS08155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ47_RS08160	COG0697	spore germination
HRJ47_RS08185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HRJ47_RS08205	COG0596	Alpha beta hydrolase
HRJ47_RS08255	COG2204	response regulator
HRJ47_RS08260	COG3852	Histidine kinase
HRJ47_RS08285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HRJ47_RS08290	COG0575	Belongs to the CDS family
HRJ47_RS08305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRJ47_RS08325	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRJ47_RS08340	COG2137	regulation of response to DNA damage stimulus
HRJ47_RS08350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HRJ47_RS08355	COG1011	Hydrolase
HRJ47_RS08370	COG1522	sequence-specific DNA binding
HRJ47_RS08380	COG1113	amino acid transport
HRJ47_RS08400	COG0659	secondary active sulfate transmembrane transporter activity
HRJ47_RS08435	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HRJ47_RS08435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ47_RS08435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ47_RS08440	COG1105	Belongs to the carbohydrate kinase PfkB family
HRJ47_RS08445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRJ47_RS08445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ47_RS08475	COG0024	Methionine aminopeptidase
HRJ47_RS08480	COG0583	DNA-binding transcription factor activity
HRJ47_RS08490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HRJ47_RS08495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HRJ47_RS08500	COG0516	GMP reductase activity
HRJ47_RS08500	COG0517	IMP dehydrogenase activity
HRJ47_RS08525	COG0552	protein localization to endoplasmic reticulum
HRJ47_RS08545	COG4890	Cyd operon protein YbgT
HRJ47_RS08550	COG1294	oxidase, subunit
HRJ47_RS08565	COG1585	Membrane protein implicated in regulation of membrane protease activity
HRJ47_RS08575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRJ47_RS08590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HRJ47_RS08595	COG0569	domain protein
HRJ47_RS08600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HRJ47_RS08630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HRJ47_RS08635	COG0542	response to heat
HRJ47_RS08660	COG0446	pyridine nucleotide-disulphide oxidoreductase
HRJ47_RS08660	COG1902	pentaerythritol trinitrate reductase activity
HRJ47_RS08700	COG0148	phosphopyruvate hydratase activity
HRJ47_RS08705	COG2323	membrane
HRJ47_RS08715	COG4773	Receptor
HRJ47_RS08720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HRJ47_RS08730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HRJ47_RS08735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HRJ47_RS08740	COG0183	Belongs to the thiolase family
HRJ47_RS08745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HRJ47_RS08750	COG0596	Alpha beta hydrolase
HRJ47_RS08755	COG2271	Major facilitator Superfamily
HRJ47_RS08760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HRJ47_RS08765	COG3485	protocatechuate 3,4-dioxygenase
HRJ47_RS08770	COG3485	protocatechuate 3,4-dioxygenase
HRJ47_RS08775	COG0710	3-dehydroquinate dehydratase activity
HRJ47_RS08780	COG3420	alginic acid biosynthetic process
HRJ47_RS08785	COG3659	wide pore channel activity
HRJ47_RS08790	COG4993	Dehydrogenase
HRJ47_RS08800	COG2391	methyltransferase activity
HRJ47_RS08815	COG1414	Transcriptional regulator
HRJ47_RS08820	COG0583	DNA-binding transcription factor activity
HRJ47_RS08825	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS08850	COG2814	Major facilitator Superfamily
HRJ47_RS08860	COG0154	amidase activity
HRJ47_RS08880	COG4638	Rieske (2fe-2S)
HRJ47_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS08900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HRJ47_RS08910	COG3733	amine oxidase
HRJ47_RS08925	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS08930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HRJ47_RS08935	COG0183	Belongs to the thiolase family
HRJ47_RS08940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HRJ47_RS08945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HRJ47_RS08955	COG4829	muconolactone delta-isomerase
HRJ47_RS08960	COG4948	Mandelate Racemase Muconate Lactonizing
HRJ47_RS08965	COG0583	DNA-binding transcription factor activity
HRJ47_RS08975	COG2186	Transcriptional regulator
HRJ47_RS08995	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS09005	COG2351	hydroxyisourate hydrolase activity
HRJ47_RS09010	COG2233	PERMEase
HRJ47_RS09020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ47_RS09025	COG2186	Transcriptional regulator
HRJ47_RS09035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HRJ47_RS09045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HRJ47_RS09065	COG1902	pentaerythritol trinitrate reductase activity
HRJ47_RS09065	COG0446	pyridine nucleotide-disulphide oxidoreductase
HRJ47_RS09075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HRJ47_RS09095	COG1309	transcriptional regulator
HRJ47_RS09100	COG0583	DNA-binding transcription factor activity
HRJ47_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09125	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS09135	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ47_RS09145	COG1309	transcriptional regulator
HRJ47_RS09235	COG0583	DNA-binding transcription factor activity
HRJ47_RS09260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HRJ47_RS09265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HRJ47_RS09310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ47_RS09325	COG2271	Major facilitator Superfamily
HRJ47_RS09370	COG2207	Transcriptional regulator
HRJ47_RS09375	COG1064	alcohol dehydrogenase
HRJ47_RS09380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ47_RS09400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HRJ47_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09410	COG3118	belongs to the thioredoxin family
HRJ47_RS09415	COG1902	pentaerythritol trinitrate reductase activity
HRJ47_RS09440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ47_RS09445	COG1120	ATPase activity
HRJ47_RS09465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HRJ47_RS09515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HRJ47_RS09555	COG2801	Transposase and inactivated derivatives
HRJ47_RS09695	COG3539	Fimbrial protein
HRJ47_RS09720	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HRJ47_RS09730	COG0753	catalase activity
HRJ47_RS09750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRJ47_RS09760	COG2205	protein histidine kinase activity
HRJ47_RS09765	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS09770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS09775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRJ47_RS09830	COG3433	isochorismatase activity
HRJ47_RS09830	COG1535	isochorismatase
HRJ47_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09840	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HRJ47_RS09845	COG4149	molybdate abc transporter
HRJ47_RS09850	COG0725	ABC transporter, periplasmic molybdate-binding protein
HRJ47_RS09860	COG4638	Rieske (2fe-2S)
HRJ47_RS09865	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HRJ47_RS09870	COG0543	2 iron, 2 sulfur cluster binding
HRJ47_RS09870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRJ47_RS09890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HRJ47_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09920	COG2207	Transcriptional regulator
HRJ47_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS09930	COG2610	gluconate transmembrane transporter activity
HRJ47_RS09970	COG0583	DNA-binding transcription factor activity
HRJ47_RS09985	COG2031	fatty acid transporter
HRJ47_RS09990	COG0183	Belongs to the thiolase family
HRJ47_RS09995	COG0583	DNA-binding transcription factor activity
HRJ47_RS10000	COG0583	DNA-binding transcription factor activity
HRJ47_RS10015	COG1027	Aspartate ammonia-lyase
HRJ47_RS10025	COG0477	Major facilitator Superfamily
HRJ47_RS10035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HRJ47_RS10040	COG1733	regulation of RNA biosynthetic process
HRJ47_RS10045	COG3708	Transcriptional regulator
HRJ47_RS10045	COG2207	Transcriptional regulator
HRJ47_RS10060	COG0730	response to heat
HRJ47_RS10065	COG3453	Protein conserved in bacteria
HRJ47_RS10065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ47_RS10080	COG3781	membrane
HRJ47_RS10085	COG1063	alcohol dehydrogenase
HRJ47_RS10095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ47_RS10100	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ47_RS10105	COG0022	dehydrogenase e1 component
HRJ47_RS10110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HRJ47_RS10115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HRJ47_RS10130	COG3706	GGDEF domain
HRJ47_RS10150	COG0133	tryptophan synthase activity
HRJ47_RS10160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HRJ47_RS10190	COG0583	DNA-binding transcription factor activity
HRJ47_RS10195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HRJ47_RS10215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HRJ47_RS10275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HRJ47_RS10280	COG4773	Receptor
HRJ47_RS10305	COG0730	response to heat
HRJ47_RS10310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HRJ47_RS10325	COG0406	alpha-ribazole phosphatase activity
HRJ47_RS10330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HRJ47_RS10345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HRJ47_RS10355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HRJ47_RS10370	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS10375	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS10380	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRJ47_RS10385	COG2207	Transcriptional regulator
HRJ47_RS10390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HRJ47_RS10395	COG0776	regulation of translation
HRJ47_RS10420	COG0822	iron-sulfur transferase activity
HRJ47_RS10425	COG0316	Belongs to the HesB IscA family
HRJ47_RS10455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HRJ47_RS10475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HRJ47_RS10480	COG0702	epimerase
HRJ47_RS10520	COG0601	transmembrane transport
HRJ47_RS10525	COG0339	signal peptide processing
HRJ47_RS10530	COG4166	transmembrane transport
HRJ47_RS10545	COG4206	TonB-dependent receptor
HRJ47_RS10575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HRJ47_RS10580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HRJ47_RS10595	COG2431	L-lysine efflux transmembrane transporter activity
HRJ47_RS10610	COG0776	regulation of translation
HRJ47_RS10675	COG0084	hydrolase, TatD family'
HRJ47_RS10695	COG1663	tetraacyldisaccharide 4'-kinase activity
HRJ47_RS10700	COG1132	(ABC) transporter
HRJ47_RS10710	COG0811	peptide transport
HRJ47_RS10715	COG1475	DNA binding
HRJ47_RS10720	COG1192	Involved in chromosome partitioning
HRJ47_RS10730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HRJ47_RS10735	COG3178	'Phosphotransferase
HRJ47_RS10745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HRJ47_RS10770	COG0424	maF-like protein
HRJ47_RS10775	COG2850	peptidyl-arginine hydroxylation
HRJ47_RS10785	COG0640	Transcriptional regulator
HRJ47_RS10795	COG3619	membrane
HRJ47_RS10800	COG3122	Protein conserved in bacteria
HRJ47_RS10805	COG1132	(ABC) transporter
HRJ47_RS10825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HRJ47_RS10830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRJ47_RS10840	COG0506	proline dehydrogenase activity
HRJ47_RS10840	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HRJ47_RS10840	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HRJ47_RS10845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HRJ47_RS10860	COG3698	Phosphodiester glycosidase
HRJ47_RS10870	COG2353	YceI-like domain
HRJ47_RS10880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HRJ47_RS10925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HRJ47_RS10925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HRJ47_RS10950	COG3539	Fimbrial protein
HRJ47_RS10975	COG0583	DNA-binding transcription factor activity
HRJ47_RS10980	COG0697	spore germination
HRJ47_RS10990	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HRJ47_RS11010	COG0583	DNA-binding transcription factor activity
HRJ47_RS11025	COG1309	transcriptional regulator
HRJ47_RS11040	COG1522	sequence-specific DNA binding
HRJ47_RS11050	COG1126	abc transporter atp-binding protein
HRJ47_RS11055	COG0765	amino acid transport
HRJ47_RS11060	COG0765	amino acid transport
HRJ47_RS11090	COG1464	Belongs to the NlpA lipoprotein family
HRJ47_RS11100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HRJ47_RS11105	COG2011	ABC-type metal ion transport system permease component
HRJ47_RS11110	COG0012	GTP binding
HRJ47_RS11135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HRJ47_RS11170	COG2207	Transcriptional regulator
HRJ47_RS11170	COG1917	Cupin 2, conserved barrel domain protein
HRJ47_RS11175	COG0386	Belongs to the glutathione peroxidase family
HRJ47_RS11185	COG0436	Aminotransferase
HRJ47_RS11190	COG1301	dicarboxylic acid transport
HRJ47_RS11225	COG3634	alkyl hydroperoxide reductase activity
HRJ47_RS11240	COG0583	DNA-binding transcription factor activity
HRJ47_RS11245	COG0431	NADPH-dependent FMN reductase
HRJ47_RS11250	COG0798	PFAM Bile acid sodium symporter
HRJ47_RS11260	COG0640	Transcriptional regulator
HRJ47_RS11275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HRJ47_RS11290	COG0583	DNA-binding transcription factor activity
HRJ47_RS11300	COG1953	Uracil, thiamine, allantoin
HRJ47_RS11310	COG2175	clavaminate synthase activity
HRJ47_RS11315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HRJ47_RS11320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HRJ47_RS11325	COG4521	taurine ABC transporter
HRJ47_RS11335	COG0477	Major facilitator Superfamily
HRJ47_RS11355	COG1271	oxidase subunit
HRJ47_RS11360	COG1294	oxidase, subunit
HRJ47_RS11400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HRJ47_RS11420	COG3052	prosthetic group binding
HRJ47_RS11425	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HRJ47_RS11450	COG1346	cytolysis
HRJ47_RS11460	COG0583	DNA-binding transcription factor activity
HRJ47_RS11465	COG0625	glutathione transferase activity
HRJ47_RS11470	COG0625	glutathione transferase activity
HRJ47_RS11475	COG0583	DNA-binding transcription factor activity
HRJ47_RS11490	COG1045	serine acetyltransferase
HRJ47_RS11495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HRJ47_RS11500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HRJ47_RS11505	COG1280	lysine exporter protein (LysE YggA)
HRJ47_RS11520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ47_RS11525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ47_RS11535	COG0765	amino acid transport
HRJ47_RS11540	COG0765	amino acid transport
HRJ47_RS11560	COG2205	protein histidine kinase activity
HRJ47_RS11560	COG0784	Response regulator, receiver
HRJ47_RS11580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HRJ47_RS11600	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS11655	COG2814	Major facilitator Superfamily
HRJ47_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ47_RS11675	COG1309	transcriptional regulator
HRJ47_RS11680	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS11685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRJ47_RS11690	COG1024	Enoyl-CoA hydratase
HRJ47_RS11695	COG4770	biotin carboxylase activity
HRJ47_RS11705	COG0583	DNA-binding transcription factor activity
HRJ47_RS11720	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS11740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HRJ47_RS11745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HRJ47_RS11750	COG2814	Major facilitator Superfamily
HRJ47_RS11755	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS11760	COG1024	Enoyl-CoA hydratase
HRJ47_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS11770	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRJ47_RS11775	COG0183	Belongs to the thiolase family
HRJ47_RS11785	COG2814	Major facilitator Superfamily
HRJ47_RS11795	COG1024	Enoyl-CoA hydratase
HRJ47_RS11805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HRJ47_RS11810	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS11815	COG2814	Major facilitator Superfamily
HRJ47_RS11820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HRJ47_RS11825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HRJ47_RS11840	COG3842	ATPase activity
HRJ47_RS11845	COG1840	ABC-type Fe3 transport system, periplasmic component
HRJ47_RS11860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ47_RS11865	COG1414	Transcriptional regulator
HRJ47_RS11885	COG2050	protein possibly involved in aromatic compounds catabolism
HRJ47_RS11895	COG3327	negative regulation of DNA-templated transcription, initiation
HRJ47_RS11900	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HRJ47_RS11905	COG0183	Belongs to the thiolase family
HRJ47_RS11910	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRJ47_RS11915	COG1024	Enoyl-CoA hydratase
HRJ47_RS11920	COG1024	Enoyl-CoA hydratase
HRJ47_RS11925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRJ47_RS11930	COG2151	metal-sulfur cluster biosynthetic enzyme
HRJ47_RS11935	COG3396	Phenylacetate-CoA oxygenase
HRJ47_RS11940	COG3460	Phenylacetate-CoA oxygenase
HRJ47_RS11945	COG3396	Phenylacetate-CoA oxygenase
HRJ47_RS11950	COG2030	dehydratase
HRJ47_RS11950	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS11955	COG1760	l-serine dehydratase
HRJ47_RS11970	COG0789	Transcriptional regulator
HRJ47_RS11980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HRJ47_RS11985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ47_RS12000	COG2807	transmembrane transport
HRJ47_RS12005	COG0590	tRNA wobble adenosine to inosine editing
HRJ47_RS12010	COG0666	response to abiotic stimulus
HRJ47_RS12055	COG2885	chlorophyll binding
HRJ47_RS12190	COG1116	anion transmembrane transporter activity
HRJ47_RS12195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ47_RS12205	COG0864	Transcriptional regulator
HRJ47_RS12215	COG1733	regulation of RNA biosynthetic process
HRJ47_RS12220	COG2249	NAD(P)H dehydrogenase (quinone) activity
HRJ47_RS12225	COG0439	Biotin carboxylase
HRJ47_RS12240	COG1063	alcohol dehydrogenase
HRJ47_RS12245	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRJ47_RS12290	COG2831	hemolysin activation secretion protein
HRJ47_RS12295	COG0038	chloride channel
HRJ47_RS12300	COG4770	biotin carboxylase activity
HRJ47_RS12320	COG1914	H( )-stimulated, divalent metal cation uptake system
HRJ47_RS12325	COG0583	DNA-binding transcription factor activity
HRJ47_RS12335	COG1595	DNA-templated transcription, initiation
HRJ47_RS12345	COG3220	belongs to the UPF0276 family
HRJ47_RS12460	COG3038	cytochrome b561
HRJ47_RS12465	COG0753	catalase activity
HRJ47_RS12480	COG2207	Transcriptional regulator
HRJ47_RS12500	COG1278	Cold shock
HRJ47_RS12535	COG1522	sequence-specific DNA binding
HRJ47_RS12540	COG0531	amino acid
HRJ47_RS12545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HRJ47_RS12560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HRJ47_RS12575	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HRJ47_RS12585	COG4122	O-methyltransferase activity
HRJ47_RS12615	COG1538	Outer membrane efflux protein
HRJ47_RS12620	COG1137	ATPase activity
HRJ47_RS12625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HRJ47_RS12635	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HRJ47_RS12685	COG2814	Major facilitator Superfamily
HRJ47_RS12695	COG0668	transmembrane transport
HRJ47_RS12740	COG1309	transcriptional regulator
HRJ47_RS12750	COG2226	methyltransferase
HRJ47_RS12755	COG1011	Hydrolase
HRJ47_RS12780	COG1278	Cold shock
HRJ47_RS12785	COG1560	Kdo2-lipid A biosynthetic process
HRJ47_RS12790	COG1280	lysine exporter protein (LysE YggA)
HRJ47_RS12825	COG1570	exodeoxyribonuclease VII activity
HRJ47_RS12910	COG2871	sodium ion transport
HRJ47_RS12920	COG0583	DNA-binding transcription factor activity
HRJ47_RS12930	COG4638	Rieske (2fe-2S)
HRJ47_RS12935	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HRJ47_RS12940	COG0543	2 iron, 2 sulfur cluster binding
HRJ47_RS12940	COG0633	Ferredoxin
HRJ47_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS12950	COG3135	benzoate transporter
HRJ47_RS12955	COG2814	Major facilitator Superfamily
HRJ47_RS12970	COG1643	Atp-dependent helicase
HRJ47_RS12995	COG3634	alkyl hydroperoxide reductase activity
HRJ47_RS13015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HRJ47_RS13025	COG0625	glutathione transferase activity
HRJ47_RS13035	COG2885	chlorophyll binding
HRJ47_RS13070	COG0542	response to heat
HRJ47_RS13085	COG1765	OsmC-like protein
HRJ47_RS13100	COG0667	Aldo Keto reductase
HRJ47_RS13115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HRJ47_RS13125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HRJ47_RS13135	COG0527	aspartate kinase activity
HRJ47_RS13145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HRJ47_RS13155	COG3038	cytochrome b561
HRJ47_RS13160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HRJ47_RS13165	COG2252	PERMEase
HRJ47_RS13175	COG1741	Belongs to the pirin family
HRJ47_RS13180	COG1309	transcriptional regulator
HRJ47_RS13195	COG2072	flavoprotein involved in K transport
HRJ47_RS13200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HRJ47_RS13205	COG0583	DNA-binding transcription factor activity
HRJ47_RS13220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HRJ47_RS13250	COG1944	ATP diphosphatase activity
HRJ47_RS13270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HRJ47_RS13285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRJ47_RS13300	COG2814	Major facilitator Superfamily
HRJ47_RS13305	COG1024	Enoyl-CoA hydratase
HRJ47_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS13320	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS13345	COG0697	spore germination
HRJ47_RS13365	COG1113	amino acid transport
HRJ47_RS13405	COG0531	amino acid
HRJ47_RS13415	COG1113	amino acid transport
HRJ47_RS13450	COG4269	membrane
HRJ47_RS13470	COG1902	pentaerythritol trinitrate reductase activity
HRJ47_RS13470	COG0446	pyridine nucleotide-disulphide oxidoreductase
HRJ47_RS13485	COG4251	negative regulation of phosphorylation
HRJ47_RS13485	COG3706	GGDEF domain
HRJ47_RS13485	COG2203	Gaf domain
HRJ47_RS13485	COG5001	Diguanylate cyclase
HRJ47_RS13495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRJ47_RS13515	COG4172	Belongs to the ABC transporter superfamily
HRJ47_RS13520	COG4239	(ABC) transporter, permease
HRJ47_RS13525	COG4174	ABC transporter (Permease)
HRJ47_RS13530	COG4166	transmembrane transport
HRJ47_RS13535	COG0741	lytic transglycosylase activity
HRJ47_RS13535	COG1388	LysM domain
HRJ47_RS13535	COG1388	LysM domain
HRJ47_RS13535	COG0741	lytic transglycosylase activity
HRJ47_RS13580	COG0583	DNA-binding transcription factor activity
HRJ47_RS13585	COG1279	arginine transmembrane transporter activity
HRJ47_RS13595	COG0789	Transcriptional regulator
HRJ47_RS13605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ47_RS13610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ47_RS13615	COG0006	proline dipeptidase activity
HRJ47_RS13655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HRJ47_RS13670	COG3384	dioxygenase
HRJ47_RS13680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRJ47_RS13685	COG2878	Part of a membrane complex involved in electron transport
HRJ47_RS13690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HRJ47_RS13715	COG0768	penicillin binding
HRJ47_RS13720	COG0742	ribosomal rna small subunit methyltransferase
HRJ47_RS13735	COG0830	nickel cation binding
HRJ47_RS13745	COG0804	urea catabolic process
HRJ47_RS13770	COG3015	lipoprotein NlpE involved in copper resistance
HRJ47_RS13785	COG1253	flavin adenine dinucleotide binding
HRJ47_RS13790	COG2851	Citrate transporter
HRJ47_RS13840	COG1773	rubredoxin
HRJ47_RS13845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ47_RS13850	COG2267	carboxylic ester hydrolase activity
HRJ47_RS13855	COG0583	DNA-binding transcription factor activity
HRJ47_RS13885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HRJ47_RS13890	COG4181	ATPase activity
HRJ47_RS13915	COG4771	TonB-dependent receptor
HRJ47_RS13935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HRJ47_RS13955	COG0306	phosphate transporter
HRJ47_RS13965	COG3958	Transketolase
HRJ47_RS13970	COG3959	Transketolase, thiamine diphosphate binding domain
HRJ47_RS13975	COG2271	Major facilitator Superfamily
HRJ47_RS13980	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS13985	COG0583	DNA-binding transcription factor activity
HRJ47_RS14000	COG2223	nitrite transmembrane transporter activity
HRJ47_RS14005	COG2207	Transcriptional regulator
HRJ47_RS14010	COG2066	Belongs to the glutaminase family
HRJ47_RS14015	COG0242	peptide deformylase activity
HRJ47_RS14020	COG0477	Major facilitator Superfamily
HRJ47_RS14030	COG0028	Belongs to the TPP enzyme family
HRJ47_RS14045	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS14050	COG2267	carboxylic ester hydrolase activity
HRJ47_RS14060	COG2271	Major facilitator Superfamily
HRJ47_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS14095	COG1414	Transcriptional regulator
HRJ47_RS14110	COG1024	Enoyl-CoA hydratase
HRJ47_RS14120	COG1215	transferase activity, transferring glycosyl groups
HRJ47_RS14125	COG0726	polysaccharide deacetylase
HRJ47_RS14125	COG1649	PFAM Uncharacterised BCR, COG1649
HRJ47_RS14135	COG4681	YaeQ
HRJ47_RS14145	COG0523	cobalamin synthesis protein
HRJ47_RS14155	COG1607	acyl-coa hydrolase
HRJ47_RS14165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HRJ47_RS14170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HRJ47_RS14175	COG1309	transcriptional regulator
HRJ47_RS14200	COG2040	homocysteine
HRJ47_RS14205	COG0531	amino acid
HRJ47_RS14260	COG1595	DNA-templated transcription, initiation
HRJ47_RS14270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRJ47_RS14275	COG0477	Major facilitator Superfamily
HRJ47_RS14335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HRJ47_RS14410	COG2026	Addiction module toxin, RelE StbE family
HRJ47_RS14560	COG3755	Protein conserved in bacteria
HRJ47_RS14605	COG1484	DNA-dependent DNA replication
HRJ47_RS14700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRJ47_RS14770	COG0405	Gamma-glutamyltransferase
HRJ47_RS14775	COG2814	Major facilitator Superfamily
HRJ47_RS14785	COG2050	protein possibly involved in aromatic compounds catabolism
HRJ47_RS14800	COG1090	epimerase
HRJ47_RS14820	COG0420	3'-5' exonuclease activity
HRJ47_RS14845	COG0735	belongs to the Fur family
HRJ47_RS14850	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRJ47_RS14855	COG2914	Belongs to the UPF0125 (RnfH) family
HRJ47_RS14870	COG0121	glutamine amidotransferase
HRJ47_RS14885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRJ47_RS14895	COG0210	DNA helicase
HRJ47_RS14900	COG2885	chlorophyll binding
HRJ47_RS14905	COG0204	Acyl-transferase
HRJ47_RS14920	COG2894	cell division
HRJ47_RS14935	COG1280	lysine exporter protein (LysE YggA)
HRJ47_RS14940	COG1674	ftsk spoiiie
HRJ47_RS14945	COG0492	ferredoxin-NADP+ reductase activity
HRJ47_RS14950	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HRJ47_RS14960	COG0456	acetyltransferase
HRJ47_RS14975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HRJ47_RS14980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HRJ47_RS14990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HRJ47_RS15005	COG1981	membrane
HRJ47_RS15015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HRJ47_RS15015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HRJ47_RS15035	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS15040	COG4638	Rieske (2fe-2S)
HRJ47_RS15045	COG0657	acetylesterase activity
HRJ47_RS15055	COG0473	3-isopropylmalate dehydrogenase activity
HRJ47_RS15060	COG0583	DNA-binding transcription factor activity
HRJ47_RS15080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HRJ47_RS15115	COG0358	DNA primase activity
HRJ47_RS15130	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HRJ47_RS15160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HRJ47_RS15190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ47_RS15200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HRJ47_RS15200	COG0352	thiamine-phosphate diphosphorylase activity
HRJ47_RS15200	COG0351	phosphomethylpyrimidine kinase
HRJ47_RS15205	COG1652	LysM domain
HRJ47_RS15230	COG1399	metal-binding, possibly nucleic acid-binding protein
HRJ47_RS15235	COG3101	peptidyl-lysine hydroxylation
HRJ47_RS15240	COG0009	L-threonylcarbamoyladenylate synthase
HRJ47_RS15245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HRJ47_RS15250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HRJ47_RS15265	COG4106	trans-aconitate 2-methyltransferase activity
HRJ47_RS15280	COG0596	Alpha beta hydrolase
HRJ47_RS15280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HRJ47_RS15280	COG2226	methyltransferase
HRJ47_RS15290	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HRJ47_RS15295	COG2223	nitrite transmembrane transporter activity
HRJ47_RS15315	COG1196	nuclear chromosome segregation
HRJ47_RS15325	COG0730	response to heat
HRJ47_RS15340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRJ47_RS15350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRJ47_RS15400	COG0489	protein tyrosine kinase activity
HRJ47_RS15410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ47_RS15410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ47_RS15445	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HRJ47_RS15450	COG2081	HI0933 family
HRJ47_RS15460	COG0668	transmembrane transport
HRJ47_RS15480	COG0583	DNA-binding transcription factor activity
HRJ47_RS15500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HRJ47_RS15505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HRJ47_RS15535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRJ47_RS15560	COG2199	diguanylate cyclase activity
HRJ47_RS15575	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS15590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HRJ47_RS15635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HRJ47_RS15650	COG0583	DNA-binding transcription factor activity
HRJ47_RS15705	COG0583	DNA-binding transcription factor activity
HRJ47_RS15720	COG0583	DNA-binding transcription factor activity
HRJ47_RS15725	COG1053	succinate dehydrogenase
HRJ47_RS15740	COG1309	transcriptional regulator
HRJ47_RS15750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HRJ47_RS15755	COG2814	Major facilitator Superfamily
HRJ47_RS15760	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS15765	COG0583	DNA-binding transcription factor activity
HRJ47_RS15770	COG1063	alcohol dehydrogenase
HRJ47_RS15800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HRJ47_RS15805	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HRJ47_RS15810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HRJ47_RS15830	COG2132	Multicopper oxidase
HRJ47_RS15840	COG0561	phosphatase activity
HRJ47_RS15845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HRJ47_RS15870	COG1214	PFAM Peptidase M22, glycoprotease
HRJ47_RS15930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HRJ47_RS15935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HRJ47_RS15940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HRJ47_RS16000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HRJ47_RS16010	COG1846	Transcriptional regulator
HRJ47_RS16015	COG1764	response to oxidative stress
HRJ47_RS16055	COG0037	tRNA processing
HRJ47_RS16065	COG0248	Ppx GppA phosphatase
HRJ47_RS16095	COG0072	phenylalanine-tRNA ligase activity
HRJ47_RS16115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HRJ47_RS16130	COG1238	metal cluster binding
HRJ47_RS16135	COG0625	glutathione transferase activity
HRJ47_RS16150	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ47_RS16155	COG3028	Belongs to the UPF0307 family
HRJ47_RS16160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ47_RS16180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRJ47_RS16185	COG0617	tRNA 3'-terminal CCA addition
HRJ47_RS16190	COG1555	photosystem II stabilization
HRJ47_RS16195	COG3956	TIGRFAM MazG family protein
HRJ47_RS16200	COG4221	oxidoreductase activity
HRJ47_RS16225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HRJ47_RS16240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ47_RS16245	COG2205	protein histidine kinase activity
HRJ47_RS16245	COG0784	Response regulator, receiver
HRJ47_RS16245	COG5002	protein histidine kinase activity
HRJ47_RS16250	COG1024	Enoyl-CoA hydratase
HRJ47_RS16255	COG2084	Dehydrogenase
HRJ47_RS16260	COG3622	Belongs to the hyi family
HRJ47_RS16290	COG0697	spore germination
HRJ47_RS16300	COG2814	Major facilitator Superfamily
HRJ47_RS16325	COG2072	flavoprotein involved in K transport
HRJ47_RS16330	COG0492	ferredoxin-NADP+ reductase activity
HRJ47_RS16335	COG0431	NADPH-dependent FMN reductase
HRJ47_RS16340	COG0798	PFAM Bile acid sodium symporter
HRJ47_RS16350	COG0640	Transcriptional regulator
HRJ47_RS16370	COG0640	Transcriptional regulator
HRJ47_RS16465	COG0583	DNA-binding transcription factor activity
HRJ47_RS16475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HRJ47_RS16485	COG0084	hydrolase, TatD family'
HRJ47_RS16500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HRJ47_RS16520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HRJ47_RS16525	COG0440	acetolactate synthase activity
HRJ47_RS16530	COG0028	Belongs to the TPP enzyme family
HRJ47_RS16550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ47_RS16555	COG1136	(ABC) transporter
HRJ47_RS16555	COG0577	efflux transmembrane transporter activity
HRJ47_RS16575	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HRJ47_RS16580	COG1162	GTPase activity
HRJ47_RS16590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HRJ47_RS16610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRJ47_RS16630	COG1426	Protein conserved in bacteria
HRJ47_RS16665	COG0793	Belongs to the peptidase S41A family
HRJ47_RS16680	COG2267	carboxylic ester hydrolase activity
HRJ47_RS16690	COG1012	belongs to the aldehyde dehydrogenase family
HRJ47_RS16695	COG3265	gluconokinase activity
HRJ47_RS16705	COG0800	Aldolase
HRJ47_RS16720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HRJ47_RS16725	COG0280	phosphate acetyltransferase
HRJ47_RS16725	COG0857	belongs to the CobB CobQ family
HRJ47_RS16730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HRJ47_RS16730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HRJ47_RS16750	COG0740	serine-type endopeptidase activity
HRJ47_RS16760	COG4774	siderophore transport
HRJ47_RS16770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRJ47_RS16780	COG2813	Specifically methylates the guanine in position
HRJ47_RS16780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HRJ47_RS16880	COG0788	formyltetrahydrofolate deformylase activity
HRJ47_RS16905	COG4651	solute:proton antiporter activity
HRJ47_RS16905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HRJ47_RS16925	COG0724	RNA recognition motif
HRJ47_RS16930	COG0210	DNA helicase
HRJ47_RS16955	COG1733	regulation of RNA biosynthetic process
HRJ47_RS16965	COG2900	Belongs to the SlyX family
HRJ47_RS16970	COG0488	(ABC) transporter
HRJ47_RS16985	COG1560	Kdo2-lipid A biosynthetic process
HRJ47_RS16995	COG1301	dicarboxylic acid transport
HRJ47_RS17050	COG0473	3-isopropylmalate dehydrogenase activity
HRJ47_RS17075	COG0583	DNA-binding transcription factor activity
HRJ47_RS17115	COG0583	DNA-binding transcription factor activity
HRJ47_RS17125	COG0625	glutathione transferase activity
HRJ47_RS17130	COG2378	regulation of single-species biofilm formation
HRJ47_RS17135	COG0546	phosphoglycolate phosphatase activity
HRJ47_RS17145	COG1530	ribonuclease E activity
HRJ47_RS17150	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ47_RS17165	COG0583	DNA-binding transcription factor activity
HRJ47_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS17175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HRJ47_RS17185	COG0534	Mate efflux family protein
HRJ47_RS17200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HRJ47_RS17225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HRJ47_RS17225	COG0493	'glutamate synthase
HRJ47_RS17235	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HRJ47_RS17240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ47_RS17255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HRJ47_RS17265	COG0644	oxidoreductase
HRJ47_RS17265	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HRJ47_RS17280	COG4535	Mg2 and Co2 transporter CorC
HRJ47_RS17290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ47_RS17310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HRJ47_RS17320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HRJ47_RS17330	COG0484	heat shock protein binding
HRJ47_RS17335	COG0789	Transcriptional regulator
HRJ47_RS17340	COG0598	Magnesium transport protein CorA
HRJ47_RS17345	COG1185	polyribonucleotide nucleotidyltransferase activity
HRJ47_RS17355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HRJ47_RS17360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HRJ47_RS17365	COG1074	ATP-dependent DNA helicase activity
HRJ47_RS17370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HRJ47_RS17390	COG2226	methyltransferase
HRJ47_RS17400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HRJ47_RS17410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HRJ47_RS17425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HRJ47_RS17425	COG2111	Na H antiporter
HRJ47_RS17430	COG1006	Multisubunit Na H antiporter MnhC subunit
HRJ47_RS17435	COG0651	ATP synthesis coupled electron transport
HRJ47_RS17440	COG1863	multisubunit Na H antiporter MnhE subunit
HRJ47_RS17445	COG2212	antiporter activity
HRJ47_RS17450	COG1320	monovalent cation:proton antiporter activity
HRJ47_RS17455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HRJ47_RS17465	COG0195	Participates in both transcription termination and antitermination
HRJ47_RS17515	COG0237	dephospho-CoA kinase activity
HRJ47_RS17525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRJ47_RS17540	COG0497	DNA recombination
HRJ47_RS17550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HRJ47_RS17585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HRJ47_RS17585	COG2169	Transcriptional regulator
HRJ47_RS17590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HRJ47_RS17665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HRJ47_RS17680	COG0326	Molecular chaperone. Has ATPase activity
HRJ47_RS17695	COG2056	Na+-H+ antiporter family
HRJ47_RS17765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HRJ47_RS17795	COG0546	phosphoglycolate phosphatase activity
HRJ47_RS17800	COG1716	ATPase activity
HRJ47_RS17845	COG0181	hydroxymethylbilane synthase activity
HRJ47_RS17855	COG3275	phosphorelay sensor kinase activity
HRJ47_RS17875	COG1538	Outer membrane efflux protein
HRJ47_RS17885	COG0697	spore germination
HRJ47_RS17915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HRJ47_RS17920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRJ47_RS17925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HRJ47_RS17930	COG0772	Belongs to the SEDS family
HRJ47_RS17955	COG4974	Belongs to the 'phage' integrase family
HRJ47_RS17960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HRJ47_RS17970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HRJ47_RS17980	COG2197	response regulator
HRJ47_RS17995	COG0793	Belongs to the peptidase S41A family
HRJ47_RS18000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HRJ47_RS18005	COG0795	lipopolysaccharide-transporting ATPase activity
HRJ47_RS18045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRJ47_RS18045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRJ47_RS18055	COG0004	ammonium transporteR
HRJ47_RS18060	COG0347	Belongs to the P(II) protein family
HRJ47_RS18070	COG0606	chelatase, subunit chli
HRJ47_RS18075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ47_RS18080	COG0235	Class ii aldolase
HRJ47_RS18085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRJ47_RS18105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HRJ47_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ47_RS18130	COG0477	Major facilitator Superfamily
HRJ47_RS18135	COG2860	membrane
HRJ47_RS18145	COG1253	flavin adenine dinucleotide binding
HRJ47_RS18155	COG2814	Major facilitator Superfamily
HRJ47_RS18165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HRJ47_RS18175	COG0745	RESPONSE REGULATOR receiver
HRJ47_RS18180	COG2205	protein histidine kinase activity
HRJ47_RS18185	COG4452	Inner membrane protein CreD
HRJ47_RS18225	COG0655	NAD(P)H dehydrogenase (quinone) activity
HRJ47_RS18240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ47_RS18270	COG1309	transcriptional regulator
HRJ47_RS18305	COG0758	DNA mediated transformation
HRJ47_RS18315	COG0697	spore germination
HRJ47_RS18320	COG1309	transcriptional regulator
HRJ47_RS18335	COG0386	Belongs to the glutathione peroxidase family
HRJ47_RS18350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HRJ47_RS18360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HRJ47_RS18400	COG1121	(ABC) transporter
HRJ47_RS18405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HRJ47_RS18410	COG1280	lysine exporter protein (LysE YggA)
HRJ47_RS18415	COG2837	iron assimilation
HRJ47_RS18420	COG0281	malic enzyme
HRJ47_RS18460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRJ47_RS18465	COG0519	Catalyzes the synthesis of GMP from XMP
HRJ47_RS18465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HRJ47_RS18470	COG4399	Belongs to the UPF0754 family
HRJ47_RS18475	COG2259	Doxx family
HRJ47_RS18480	COG0586	Pfam SNARE associated Golgi protein
HRJ47_RS18495	COG1192	Involved in chromosome partitioning
HRJ47_RS18505	COG0271	Belongs to the BolA IbaG family
HRJ47_RS18545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HRJ47_RS18545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HRJ47_RS18545	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HRJ47_RS18545	COG3321	synthase
HRJ47_RS18550	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS18560	COG2197	response regulator
HRJ47_RS18570	COG3916	Acyl-homoserine-lactone synthase
HRJ47_RS18575	COG0477	Major facilitator Superfamily
HRJ47_RS18580	COG1024	Enoyl-CoA hydratase
HRJ47_RS18585	COG1024	Enoyl-CoA hydratase
HRJ47_RS18590	COG1960	acyl-CoA dehydrogenase activity
HRJ47_RS18595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRJ47_RS18615	COG1113	amino acid transport
HRJ47_RS18620	COG1113	amino acid transport
HRJ47_RS18625	COG0251	oxidation-reduction process
HRJ47_RS18665	COG0564	pseudouridine synthase activity
HRJ47_RS18690	COG1309	transcriptional regulator
HRJ47_RS18695	COG1309	transcriptional regulator
HRJ47_RS18705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HRJ47_RS18780	COG1051	belongs to the nudix hydrolase family
HRJ47_RS18805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HRJ47_RS18820	COG1802	Transcriptional regulator
HRJ47_RS18830	COG1448	Aminotransferase
HRJ47_RS18835	COG0277	FAD linked oxidase domain protein
HRJ47_RS18845	COG2186	Transcriptional regulator
HRJ47_RS18850	COG1620	l-lactate permease
HRJ47_RS18855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRJ47_RS18865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HRJ47_RS18880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HRJ47_RS18885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HRJ47_RS18905	COG0438	transferase activity, transferring glycosyl groups
HRJ47_RS18910	COG1215	transferase activity, transferring glycosyl groups
HRJ47_RS18930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HRJ47_RS18940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HRJ47_RS18945	COG1596	polysaccharide export
HRJ47_RS18975	COG0728	peptidoglycan biosynthetic process
HRJ47_RS18980	COG3023	N-Acetylmuramoyl-L-alanine amidase
HRJ47_RS19035	COG0546	phosphoglycolate phosphatase activity
HRJ47_RS19040	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ47_RS19055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HRJ47_RS19055	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HRJ47_RS19060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HRJ47_RS19065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HRJ47_RS19070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HRJ47_RS19075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HRJ47_RS19080	COG1116	anion transmembrane transporter activity
HRJ47_RS19085	COG1309	transcriptional regulator
HRJ47_RS19090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HRJ47_RS19100	COG0196	riboflavin kinase activity
HRJ47_RS19105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HRJ47_RS19115	COG1047	Peptidyl-prolyl cis-trans
HRJ47_RS19155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HRJ47_RS19160	COG0657	acetylesterase activity
HRJ47_RS19210	COG2951	lytic endotransglycosylase activity
HRJ47_RS19215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HRJ47_RS19230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HRJ47_RS19240	COG0671	phosphoesterase, PA-phosphatase related
HRJ47_RS19245	COG0861	Integral membrane protein TerC family
HRJ47_RS19255	COG0754	glutathionylspermidine amidase activity
HRJ47_RS19260	COG3293	Transposase
HRJ47_RS19270	COG0402	S-adenosylhomocysteine deaminase activity
HRJ47_RS19285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HRJ47_RS19290	COG1230	cation diffusion facilitator family transporter
HRJ47_RS19305	COG0706	membrane insertase activity
HRJ47_RS19475	COG1192	Involved in chromosome partitioning
HRJ47_RS19480	COG1475	DNA binding
HRJ47_RS19670	COG3173	Aminoglycoside phosphotransferase
HRJ47_RS19750	COG3293	Transposase
HRJ47_RS19770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HRJ47_RS19780	COG0673	inositol 2-dehydrogenase activity
HRJ47_RS19830	COG2826	transposase and inactivated derivatives, IS30 family
HRJ47_RS19840	COG2826	transposase and inactivated derivatives, IS30 family
HRJ47_RS19875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HRJ47_RS19935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HRJ47_RS19975	COG1660	Displays ATPase and GTPase activities
HRJ47_RS20015	COG3173	Aminoglycoside phosphotransferase
HRJ47_RS20020	COG0488	(ABC) transporter
HRJ47_RS20040	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HRJ47_RS20045	COG3657	addiction module killer protein
HRJ47_RS20060	COG2801	Transposase and inactivated derivatives
HRJ47_RS20070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRJ47_RS20095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism