locus-tag	class	description
DLK06_RS00010	COG0592	DNA-directed DNA polymerase activity
DLK06_RS00020	COG0187	DNA topoisomerase II activity
DLK06_RS00035	COG0488	(ABC) transporter
DLK06_RS00060	COG0596	Alpha beta hydrolase
DLK06_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DLK06_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DLK06_RS00105	COG0625	glutathione transferase activity
DLK06_RS00115	COG0733	neurotransmitter:sodium symporter activity
DLK06_RS00155	COG2233	PERMEase
DLK06_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS00205	COG2814	Major facilitator Superfamily
DLK06_RS00210	COG0656	L-ascorbic acid biosynthetic process
DLK06_RS00215	COG0583	DNA-binding transcription factor activity
DLK06_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLK06_RS00235	COG1064	alcohol dehydrogenase
DLK06_RS00240	COG2818	Glycosylase
DLK06_RS00255	COG1194	a g-specific adenine glycosylase
DLK06_RS00270	COG5487	UPF0391 membrane protein
DLK06_RS00275	COG2983	Belongs to the UPF0260 family
DLK06_RS00280	COG2133	pyrroloquinoline quinone binding
DLK06_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DLK06_RS00290	COG2116	formate transmembrane transporter activity
DLK06_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLK06_RS00320	COG0385	Bile acid
DLK06_RS00340	COG1683	Conserved Protein
DLK06_RS00355	COG0346	lactoylglutathione lyase activity
DLK06_RS00360	COG0625	glutathione transferase activity
DLK06_RS00370	COG1113	amino acid transport
DLK06_RS00380	COG0523	cobalamin synthesis protein
DLK06_RS00390	COG2188	Transcriptional regulator
DLK06_RS00420	COG0010	Belongs to the arginase family
DLK06_RS00430	COG0546	phosphoglycolate phosphatase activity
DLK06_RS00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DLK06_RS00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DLK06_RS00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DLK06_RS00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DLK06_RS00570	COG0534	Mate efflux family protein
DLK06_RS00575	COG0436	Aminotransferase
DLK06_RS00580	COG2733	membrane
DLK06_RS00595	COG2918	glutathione biosynthetic process
DLK06_RS00610	COG3179	chitinase
DLK06_RS00625	COG3150	esterase
DLK06_RS00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DLK06_RS00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLK06_RS00655	COG2233	PERMEase
DLK06_RS00660	COG2351	hydroxyisourate hydrolase activity
DLK06_RS00695	COG3706	GGDEF domain
DLK06_RS00710	COG1393	Belongs to the ArsC family
DLK06_RS00715	COG0708	Exodeoxyribonuclease III
DLK06_RS00740	COG0189	ligase activity
DLK06_RS00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DLK06_RS00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DLK06_RS00785	COG4942	peptidase
DLK06_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLK06_RS00805	COG2119	membrane
DLK06_RS00810	COG4774	siderophore transport
DLK06_RS00815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLK06_RS00815	COG0426	domain, Protein
DLK06_RS00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DLK06_RS00860	COG1902	pentaerythritol trinitrate reductase activity
DLK06_RS00865	COG1519	Transferase
DLK06_RS00870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DLK06_RS00875	COG0668	transmembrane transport
DLK06_RS00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLK06_RS00890	COG1335	isochorismatase
DLK06_RS00895	COG1522	sequence-specific DNA binding
DLK06_RS00920	COG2205	protein histidine kinase activity
DLK06_RS00920	COG0784	Response regulator, receiver
DLK06_RS00920	COG2198	Histidine kinase
DLK06_RS00925	COG3162	membrane
DLK06_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DLK06_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DLK06_RS00960	COG1309	transcriptional regulator
DLK06_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DLK06_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
DLK06_RS00980	COG0351	phosphomethylpyrimidine kinase
DLK06_RS00990	COG2814	Major facilitator Superfamily
DLK06_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DLK06_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLK06_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS01040	COG1335	isochorismatase
DLK06_RS01130	COG1309	transcriptional regulator
DLK06_RS01150	COG2814	Major facilitator Superfamily
DLK06_RS01155	COG0583	DNA-binding transcription factor activity
DLK06_RS01175	COG0667	Aldo Keto reductase
DLK06_RS01225	COG1733	regulation of RNA biosynthetic process
DLK06_RS01235	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLK06_RS01280	COG1881	PFAM PEBP family protein
DLK06_RS01285	COG2977	Belongs to the P-Pant transferase superfamily
DLK06_RS01290	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DLK06_RS01295	COG2207	Transcriptional regulator
DLK06_RS01355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DLK06_RS01370	COG2329	Antibiotic biosynthesis monooxygenase
DLK06_RS01385	COG1132	(ABC) transporter
DLK06_RS01395	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DLK06_RS01405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DLK06_RS01435	COG0427	acetyl-CoA hydrolase
DLK06_RS01460	COG0659	secondary active sulfate transmembrane transporter activity
DLK06_RS01465	COG4221	oxidoreductase activity
DLK06_RS01470	COG2873	o-acetylhomoserine
DLK06_RS01475	COG0488	(ABC) transporter
DLK06_RS01560	COG0833	amino acid
DLK06_RS01605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DLK06_RS01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DLK06_RS01625	COG2226	methyltransferase
DLK06_RS01675	COG0070	glutamate synthase
DLK06_RS01675	COG0069	glutamate synthase activity
DLK06_RS01675	COG0067	glutamate synthase
DLK06_RS01680	COG0493	'glutamate synthase
DLK06_RS01690	COG1704	LemA family
DLK06_RS01695	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DLK06_RS01715	COG3307	-O-antigen
DLK06_RS01740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLK06_RS01755	COG0194	GDP metabolic process
DLK06_RS01805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DLK06_RS01815	COG0335	large ribosomal subunit rRNA binding
DLK06_RS01825	COG5380	lipid catabolic process
DLK06_RS01830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DLK06_RS01845	COG5006	permease, DMT superfamily
DLK06_RS01850	COG5006	permease, DMT superfamily
DLK06_RS01855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLK06_RS01860	COG0277	FAD linked oxidase domain protein
DLK06_RS01870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DLK06_RS01875	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLK06_RS01890	COG1289	transmembrane transporter activity
DLK06_RS01900	COG0628	permease
DLK06_RS01905	COG1192	Involved in chromosome partitioning
DLK06_RS01935	COG0833	amino acid
DLK06_RS01940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DLK06_RS01945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DLK06_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS01995	COG0583	DNA-binding transcription factor activity
DLK06_RS02025	COG0752	glycyl-tRNA synthetase alpha subunit
DLK06_RS02050	COG4109	DRTGG domain
DLK06_RS02055	COG1983	PspC domain protein
DLK06_RS02065	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS02080	COG0408	coproporphyrinogen oxidase activity
DLK06_RS02100	COG0513	Belongs to the DEAD box helicase family
DLK06_RS02110	COG1127	ABC transporter
DLK06_RS02115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DLK06_RS02125	COG2854	intermembrane phospholipid transfer
DLK06_RS02135	COG0598	Magnesium transport protein CorA
DLK06_RS02145	COG0494	nUDIX hydrolase
DLK06_RS02150	COG1040	competence protein
DLK06_RS02155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DLK06_RS02175	COG1946	Acyl-CoA thioesterase
DLK06_RS02180	COG1301	dicarboxylic acid transport
DLK06_RS02195	COG1959	2 iron, 2 sulfur cluster binding
DLK06_RS02200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLK06_RS02200	COG1017	nitric oxide dioxygenase activity
DLK06_RS02210	COG0433	COG0433 Predicted ATPase
DLK06_RS02215	COG0626	cystathionine gamma-synthase activity
DLK06_RS02230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DLK06_RS02235	COG0088	Forms part of the polypeptide exit tunnel
DLK06_RS02370	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS02375	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DLK06_RS02405	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DLK06_RS02410	COG0339	signal peptide processing
DLK06_RS02415	COG0557	exoribonuclease II activity
DLK06_RS02465	COG0179	Fumarylacetoacetate (FAA) hydrolase
DLK06_RS02470	COG1295	ribonuclease BN
DLK06_RS02505	COG1702	phosphate starvation-inducible protein PhoH
DLK06_RS02515	COG0739	heme binding
DLK06_RS02515	COG0741	lytic transglycosylase activity
DLK06_RS02515	COG1196	nuclear chromosome segregation
DLK06_RS02545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DLK06_RS02550	COG1183	phosphatidylcholine synthase activity
DLK06_RS02595	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS02600	COG1309	transcriptional regulator
DLK06_RS02615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DLK06_RS02620	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS02660	COG2969	positive regulation of protein catabolic process
DLK06_RS02670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DLK06_RS02675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DLK06_RS02680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DLK06_RS02685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DLK06_RS02690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DLK06_RS02710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DLK06_RS02720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DLK06_RS02725	COG1408	metallophosphoesterase
DLK06_RS02730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DLK06_RS02730	COG2885	chlorophyll binding
DLK06_RS02735	COG2199	diguanylate cyclase activity
DLK06_RS02780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLK06_RS02800	COG4372	Transposase
DLK06_RS02825	COG1607	acyl-coa hydrolase
DLK06_RS02870	COG0613	PHP domain protein
DLK06_RS02875	COG3781	membrane
DLK06_RS02885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DLK06_RS02890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DLK06_RS02900	COG1862	Preprotein translocase
DLK06_RS02920	COG0784	Response regulator, receiver
DLK06_RS02920	COG2198	Histidine kinase
DLK06_RS02920	COG2205	protein histidine kinase activity
DLK06_RS02920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK06_RS02925	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DLK06_RS02940	COG0726	polysaccharide deacetylase
DLK06_RS02955	COG1216	Glycosyl transferase, family 2
DLK06_RS03005	COG0625	glutathione transferase activity
DLK06_RS03010	COG0583	DNA-binding transcription factor activity
DLK06_RS03015	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS03020	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS03030	COG2205	protein histidine kinase activity
DLK06_RS03035	COG0745	RESPONSE REGULATOR receiver
DLK06_RS03050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DLK06_RS03070	COG2096	Adenosyltransferase
DLK06_RS03120	COG0285	dihydrofolate synthase activity
DLK06_RS03140	COG0450	alkyl hydroperoxide reductase
DLK06_RS03155	COG0477	Major facilitator Superfamily
DLK06_RS03160	COG1272	protein, Hemolysin III
DLK06_RS03170	COG2153	protein acetylation
DLK06_RS03190	COG0183	Belongs to the thiolase family
DLK06_RS03195	COG2207	Transcriptional regulator
DLK06_RS03215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DLK06_RS03235	COG0183	Belongs to the thiolase family
DLK06_RS03245	COG2885	chlorophyll binding
DLK06_RS03245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DLK06_RS03250	COG1690	Belongs to the RtcB family
DLK06_RS03255	COG0833	amino acid
DLK06_RS03265	COG2233	PERMEase
DLK06_RS03270	COG1217	gtp-binding protein TYPA
DLK06_RS03310	COG2094	Belongs to the DNA glycosylase MPG family
DLK06_RS03320	COG1902	pentaerythritol trinitrate reductase activity
DLK06_RS03335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLK06_RS03340	COG0354	folic acid binding
DLK06_RS03360	COG2233	PERMEase
DLK06_RS03365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLK06_RS03370	COG0251	oxidation-reduction process
DLK06_RS03375	COG1335	isochorismatase
DLK06_RS03380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLK06_RS03385	COG0778	Nitroreductase
DLK06_RS03390	COG0596	Alpha beta hydrolase
DLK06_RS03395	COG3189	MarR family transcriptional regulator
DLK06_RS03400	COG2824	Alkylphosphonate utilization operon protein PhnA
DLK06_RS03405	COG3422	double-strand break repair
DLK06_RS03450	COG0840	transmembrane signaling receptor activity
DLK06_RS03470	COG5510	response to toxic substance
DLK06_RS03480	COG2832	Protein of unknown function (DUF454)
DLK06_RS03485	COG1376	ErfK ybiS ycfS ynhG family protein
DLK06_RS03525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DLK06_RS03535	COG1289	transmembrane transporter activity
DLK06_RS03540	COG2814	Major facilitator Superfamily
DLK06_RS03560	COG1115	amino acid carrier protein
DLK06_RS03565	COG1752	Esterase of the alpha-beta hydrolase superfamily
DLK06_RS03570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DLK06_RS03575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DLK06_RS03580	COG3590	peptidase
DLK06_RS03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DLK06_RS03615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DLK06_RS03620	COG1077	Cell shape determining protein MreB Mrl
DLK06_RS03625	COG1792	Involved in formation and maintenance of cell shape
DLK06_RS03630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DLK06_RS03635	COG0424	maF-like protein
DLK06_RS03640	COG1530	ribonuclease E activity
DLK06_RS03650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DLK06_RS03670	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLK06_RS03695	COG2207	Transcriptional regulator
DLK06_RS03715	COG0464	growth
DLK06_RS03780	COG2826	transposase and inactivated derivatives, IS30 family
DLK06_RS03800	COG0673	inositol 2-dehydrogenase activity
DLK06_RS03805	COG1324	tolerance protein
DLK06_RS03835	COG2826	transposase and inactivated derivatives, IS30 family
DLK06_RS03845	COG0305	Participates in initiation and elongation during chromosome replication
DLK06_RS03880	COG0582	viral genome integration into host DNA
DLK06_RS03900	COG3046	protein related to deoxyribodipyrimidine photolyase
DLK06_RS03910	COG1113	amino acid transport
DLK06_RS03915	COG2828	Protein conserved in bacteria
DLK06_RS03920	COG0142	geranyltranstransferase activity
DLK06_RS03925	COG2315	Protein conserved in bacteria
DLK06_RS03940	COG1752	Esterase of the alpha-beta hydrolase superfamily
DLK06_RS03975	COG4372	Transposase
DLK06_RS03980	COG2194	sulfuric ester hydrolase activity
DLK06_RS03985	COG0745	RESPONSE REGULATOR receiver
DLK06_RS03990	COG0642	Histidine kinase
DLK06_RS04000	COG0004	ammonium transporteR
DLK06_RS04005	COG0583	DNA-binding transcription factor activity
DLK06_RS04025	COG0525	valine-tRNA ligase activity
DLK06_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS04045	COG0393	Putative heavy-metal-binding
DLK06_RS04050	COG0393	Putative heavy-metal-binding
DLK06_RS04055	COG1538	Outer membrane efflux protein
DLK06_RS04065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS04070	COG0671	phosphoesterase, PA-phosphatase related
DLK06_RS04095	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DLK06_RS04110	COG1648	precorrin-2 dehydrogenase activity
DLK06_RS04110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLK06_RS04115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DLK06_RS04165	COG0531	amino acid
DLK06_RS04180	COG0321	lipoyl(octanoyl) transferase activity
DLK06_RS04185	COG2921	Belongs to the UPF0250 family
DLK06_RS04225	COG2009	succinate dehydrogenase
DLK06_RS04230	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DLK06_RS04235	COG1053	succinate dehydrogenase
DLK06_RS04240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DLK06_RS04265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLK06_RS04300	COG2354	Protein conserved in bacteria
DLK06_RS04305	COG2321	neutral zinc metallopeptidase
DLK06_RS04325	COG2843	Capsule synthesis protein
DLK06_RS04345	COG0589	response to stress
DLK06_RS04355	COG0251	oxidation-reduction process
DLK06_RS04360	COG1309	transcriptional regulator
DLK06_RS04375	COG0505	Belongs to the CarA family
DLK06_RS04410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLK06_RS04415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DLK06_RS04435	COG3540	Alkaline phosphatase
DLK06_RS04470	COG0477	Major facilitator Superfamily
DLK06_RS04475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DLK06_RS04490	COG1597	lipid kinase activity
DLK06_RS04495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DLK06_RS04535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLK06_RS04550	COG3620	sequence-specific DNA binding
DLK06_RS04730	COG0582	viral genome integration into host DNA
DLK06_RS04745	COG0584	glycerophosphoryl diester phosphodiesterase
DLK06_RS04765	COG0741	lytic transglycosylase activity
DLK06_RS04790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DLK06_RS04795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DLK06_RS04835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS04845	COG0778	Nitroreductase
DLK06_RS04850	COG0300	oxidoreductase activity
DLK06_RS04885	COG0243	molybdopterin cofactor binding
DLK06_RS04890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DLK06_RS04895	COG3339	Conserved Protein
DLK06_RS04920	COG1115	amino acid carrier protein
DLK06_RS04925	COG1113	amino acid transport
DLK06_RS04935	COG0019	diaminopimelate decarboxylase activity
DLK06_RS04945	COG1280	lysine exporter protein (LysE YggA)
DLK06_RS04950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DLK06_RS04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS05010	COG4591	ABC-type transport system involved in lipoprotein release permease component
DLK06_RS05015	COG1136	(ABC) transporter
DLK06_RS05020	COG2333	competence protein COMEC
DLK06_RS05020	COG0658	competence protein
DLK06_RS05030	COG0616	signal peptide processing
DLK06_RS05030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DLK06_RS05035	COG0596	Alpha beta hydrolase
DLK06_RS05040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DLK06_RS05050	COG0628	permease
DLK06_RS05070	COG4372	Transposase
DLK06_RS05105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLK06_RS05125	COG0823	Involved in the tonB-independent uptake of proteins
DLK06_RS05145	COG0824	Thioesterase
DLK06_RS05150	COG1473	amidohydrolase
DLK06_RS05170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DLK06_RS05170	COG0047	phosphoribosylformylglycinamidine synthase activity
DLK06_RS05175	COG2814	Major facilitator Superfamily
DLK06_RS05180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DLK06_RS05185	COG1024	Enoyl-CoA hydratase
DLK06_RS05190	COG1056	cytidyltransferase-related domain
DLK06_RS05190	COG1051	belongs to the nudix hydrolase family
DLK06_RS05205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DLK06_RS05220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DLK06_RS05235	COG4625	pathogenesis
DLK06_RS05240	COG0583	DNA-binding transcription factor activity
DLK06_RS05245	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DLK06_RS05250	COG4208	sulfate ABC transporter
DLK06_RS05255	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DLK06_RS05265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DLK06_RS05270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DLK06_RS05275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DLK06_RS05295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLK06_RS05310	COG0481	GTPase activity
DLK06_RS05315	COG0681	Belongs to the peptidase S26 family
DLK06_RS05325	COG0571	ribonuclease III activity
DLK06_RS05330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DLK06_RS05340	COG1381	Involved in DNA repair and RecF pathway recombination
DLK06_RS05345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DLK06_RS05355	COG4221	oxidoreductase activity
DLK06_RS05385	COG0436	Aminotransferase
DLK06_RS05405	COG0556	nucleotide-excision repair
DLK06_RS05415	COG2962	Rard protein
DLK06_RS05460	COG2070	2-Nitropropane dioxygenase
DLK06_RS05475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DLK06_RS05490	COG1215	transferase activity, transferring glycosyl groups
DLK06_RS05505	COG0415	Belongs to the DNA photolyase family
DLK06_RS05515	COG1252	NADH dehydrogenase
DLK06_RS05520	COG1686	Belongs to the peptidase S11 family
DLK06_RS05535	COG1187	pseudouridine synthase activity
DLK06_RS05545	COG0477	Major facilitator Superfamily
DLK06_RS05550	COG0583	DNA-binding transcription factor activity
DLK06_RS05555	COG1823	symporter activity
DLK06_RS05565	COG0612	Peptidase, M16
DLK06_RS05590	COG0352	thiamine-phosphate diphosphorylase activity
DLK06_RS05625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLK06_RS05640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLK06_RS05645	COG0076	glutamate decarboxylase activity
DLK06_RS05655	COG1522	sequence-specific DNA binding
DLK06_RS05660	COG3961	Belongs to the TPP enzyme family
DLK06_RS05665	COG1113	amino acid transport
DLK06_RS05670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DLK06_RS05675	COG0573	inorganic phosphate transmembrane transporter activity
DLK06_RS05685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DLK06_RS05690	COG0616	signal peptide processing
DLK06_RS05730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DLK06_RS05735	COG1686	Belongs to the peptidase S11 family
DLK06_RS05760	COG0583	DNA-binding transcription factor activity
DLK06_RS05765	COG1067	ATP-dependent peptidase activity
DLK06_RS05770	COG2211	Major facilitator Superfamily
DLK06_RS05805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DLK06_RS05810	COG1966	Carbon starvation protein
DLK06_RS05815	COG2879	small protein
DLK06_RS05865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DLK06_RS05875	COG1741	Belongs to the pirin family
DLK06_RS05890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DLK06_RS05895	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLK06_RS05900	COG4605	iron ion homeostasis
DLK06_RS05905	COG4604	ABC transporter, ATP-binding protein
DLK06_RS05910	COG4607	ABC-type enterochelin transport system periplasmic component
DLK06_RS05915	COG4774	siderophore transport
DLK06_RS05925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DLK06_RS05930	COG1021	2,3-dihydroxybenzoate-AMP ligase
DLK06_RS05935	COG1535	isochorismatase
DLK06_RS05935	COG3433	isochorismatase activity
DLK06_RS05950	COG1132	(ABC) transporter
DLK06_RS05955	COG1132	(ABC) transporter
DLK06_RS05960	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DLK06_RS05970	COG1169	isochorismate synthase
DLK06_RS05990	COG3739	integral membrane protein
DLK06_RS06010	COG0302	gtp cyclohydrolase
DLK06_RS06020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DLK06_RS06030	COG2840	Smr protein MutS2
DLK06_RS06050	COG0308	aminopeptidase N
DLK06_RS06055	COG0512	Glutamine amidotransferase of anthranilate synthase
DLK06_RS06070	COG0174	glutamine synthetase
DLK06_RS06080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DLK06_RS06115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DLK06_RS06120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DLK06_RS06125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLK06_RS06145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DLK06_RS06150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DLK06_RS06155	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DLK06_RS06170	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS06175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DLK06_RS06180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLK06_RS06190	COG2223	nitrite transmembrane transporter activity
DLK06_RS06200	COG0024	Methionine aminopeptidase
DLK06_RS06205	COG0052	Belongs to the universal ribosomal protein uS2 family
DLK06_RS06245	COG2951	lytic endotransglycosylase activity
DLK06_RS06250	COG0772	Belongs to the SEDS family
DLK06_RS06265	COG0842	Transport permease protein
DLK06_RS06270	COG1131	(ABC) transporter
DLK06_RS06345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS06355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK06_RS06360	COG4215	(ABC) transporter
DLK06_RS06365	COG4160	amino acid transport
DLK06_RS06370	COG4598	ABC transporter
DLK06_RS06380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLK06_RS06385	COG0826	peptidase U32
DLK06_RS06390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLK06_RS06395	COG0384	phenazine biosynthesis protein PhzF
DLK06_RS06405	COG1720	tRNA m6t6A37 methyltransferase activity
DLK06_RS06415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DLK06_RS06430	COG0642	Histidine kinase
DLK06_RS06440	COG0494	nUDIX hydrolase
DLK06_RS06450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DLK06_RS06455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DLK06_RS06460	COG3139	Protein of unknown function (DUF1315)
DLK06_RS06465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DLK06_RS06475	COG1301	dicarboxylic acid transport
DLK06_RS06480	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS06495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DLK06_RS06505	COG2195	Cleaves the N-terminal amino acid of tripeptides
DLK06_RS06525	COG1690	Belongs to the RtcB family
DLK06_RS06530	COG1234	tRNA 3'-trailer cleavage
DLK06_RS06535	COG4650	regulator
DLK06_RS06565	COG2363	Small membrane protein
DLK06_RS06585	COG0513	Belongs to the DEAD box helicase family
DLK06_RS06595	COG0778	Nitroreductase
DLK06_RS06625	COG1286	toxin biosynthetic process
DLK06_RS06650	COG4783	chaperone-mediated protein folding
DLK06_RS06655	COG1610	YqeY-like protein
DLK06_RS06685	COG0515	serine threonine protein kinase
DLK06_RS06685	COG2815	serine threonine protein kinase
DLK06_RS06710	COG1278	Cold shock
DLK06_RS06725	COG3243	poly(R)-hydroxyalkanoic acid synthase
DLK06_RS06730	COG0786	glutamate:sodium symporter activity
DLK06_RS06735	COG0475	glutathione-regulated potassium exporter activity
DLK06_RS06735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLK06_RS06810	COG1309	transcriptional regulator
DLK06_RS06820	COG2985	domain, Protein
DLK06_RS06830	COG2995	paraquat-inducible protein a
DLK06_RS06835	COG3008	intermembrane lipid transfer
DLK06_RS06835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DLK06_RS06845	COG2351	hydroxyisourate hydrolase activity
DLK06_RS06885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DLK06_RS06895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DLK06_RS06900	COG0642	Histidine kinase
DLK06_RS06905	COG0745	RESPONSE REGULATOR receiver
DLK06_RS06925	COG1794	racemase activity, acting on amino acids and derivatives
DLK06_RS06935	COG2175	clavaminate synthase activity
DLK06_RS06940	COG3246	L-lysine catabolic process to acetate
DLK06_RS06945	COG2814	Major facilitator Superfamily
DLK06_RS06960	COG2855	membrane
DLK06_RS07010	COG1301	dicarboxylic acid transport
DLK06_RS07020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLK06_RS07025	COG2011	ABC-type metal ion transport system permease component
DLK06_RS07030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DLK06_RS07040	COG0151	Belongs to the GarS family
DLK06_RS07050	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DLK06_RS07080	COG2308	Evidence 4 Homologs of previously reported genes of
DLK06_RS07090	COG1305	Transglutaminase-like
DLK06_RS07100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DLK06_RS07105	COG0305	Participates in initiation and elongation during chromosome replication
DLK06_RS07130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DLK06_RS07135	COG1845	cytochrome c oxidase, subunit III
DLK06_RS07140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DLK06_RS07170	COG1649	PFAM Uncharacterised BCR, COG1649
DLK06_RS07170	COG0726	polysaccharide deacetylase
DLK06_RS07175	COG1215	transferase activity, transferring glycosyl groups
DLK06_RS07180	COG3658	cytochrome
DLK06_RS07190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLK06_RS07210	COG2890	protein-(glutamine-N5) methyltransferase activity
DLK06_RS07215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLK06_RS07220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLK06_RS07235	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS07240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLK06_RS07255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DLK06_RS07265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DLK06_RS07270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DLK06_RS07280	COG2205	protein histidine kinase activity
DLK06_RS07285	COG0745	RESPONSE REGULATOR receiver
DLK06_RS07290	COG0174	glutamine synthetase
DLK06_RS07305	COG0477	Major facilitator Superfamily
DLK06_RS07310	COG0729	surface antigen
DLK06_RS07345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLK06_RS07350	COG2814	Major facilitator Superfamily
DLK06_RS07455	COG2369	cell adhesion
DLK06_RS07460	COG4383	Mu-like prophage protein gp29
DLK06_RS07475	COG4373	Mu-like prophage FluMu protein gp28
DLK06_RS07510	COG0681	Belongs to the peptidase S26 family
DLK06_RS07535	COG3409	Peptidoglycan-binding domain 1 protein
DLK06_RS07535	COG3267	Type II secretory pathway component ExeA
DLK06_RS07610	COG0583	DNA-binding transcription factor activity
DLK06_RS07625	COG1187	pseudouridine synthase activity
DLK06_RS07645	COG0802	atpase or kinase
DLK06_RS07650	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DLK06_RS07660	COG1923	regulation of RNA biosynthetic process
DLK06_RS07665	COG0697	spore germination
DLK06_RS07680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLK06_RS07690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLK06_RS07700	COG2826	transposase and inactivated derivatives, IS30 family
DLK06_RS07710	COG4302	ethanolamine ammonia-lyase activity
DLK06_RS07715	COG4303	Ethanolamine ammonia lyase large subunit
DLK06_RS07720	COG0531	amino acid
DLK06_RS07740	COG1454	alcohol dehydrogenase
DLK06_RS07745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DLK06_RS07770	COG0308	aminopeptidase N
DLK06_RS07810	COG1605	Chorismate mutase
DLK06_RS07830	COG4772	TonB-dependent receptor
DLK06_RS07835	COG4774	siderophore transport
DLK06_RS07890	COG3772	lysozyme
DLK06_RS07915	COG0583	DNA-binding transcription factor activity
DLK06_RS07920	COG4372	Transposase
DLK06_RS07970	COG0488	(ABC) transporter
DLK06_RS07975	COG0589	response to stress
DLK06_RS07995	COG3135	benzoate transporter
DLK06_RS08000	COG1522	sequence-specific DNA binding
DLK06_RS08010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DLK06_RS08015	COG0583	DNA-binding transcription factor activity
DLK06_RS08025	COG0183	Belongs to the thiolase family
DLK06_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS08035	COG2030	dehydratase
DLK06_RS08065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DLK06_RS08075	COG0824	Thioesterase
DLK06_RS08080	COG1454	alcohol dehydrogenase
DLK06_RS08105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DLK06_RS08135	COG0069	glutamate synthase activity
DLK06_RS08455	COG0741	lytic transglycosylase activity
DLK06_RS08455	COG0739	heme binding
DLK06_RS08455	COG1196	nuclear chromosome segregation
DLK06_RS08505	COG2194	sulfuric ester hydrolase activity
DLK06_RS08510	COG2814	Major facilitator Superfamily
DLK06_RS08525	COG0511	ligase activity, forming carbon-carbon bonds
DLK06_RS08550	COG4264	IucA IucC family
DLK06_RS08560	COG4264	IucA IucC family
DLK06_RS08565	COG2423	ornithine cyclodeaminase activity
DLK06_RS08570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DLK06_RS08575	COG1116	anion transmembrane transporter activity
DLK06_RS08575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLK06_RS08590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DLK06_RS08590	COG2146	nitrite reductase [NAD(P)H] activity
DLK06_RS08595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DLK06_RS08600	COG0243	molybdopterin cofactor binding
DLK06_RS08610	COG0243	molybdopterin cofactor binding
DLK06_RS08615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DLK06_RS08630	COG0521	Mo-molybdopterin cofactor biosynthetic process
DLK06_RS08630	COG0315	cyclic pyranopterin monophosphate synthase activity
DLK06_RS08635	COG0303	'Molybdopterin
DLK06_RS08645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLK06_RS08650	COG0697	spore germination
DLK06_RS08675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DLK06_RS08700	COG4372	Transposase
DLK06_RS08720	COG4372	Transposase
DLK06_RS08725	COG0596	Alpha beta hydrolase
DLK06_RS08785	COG2204	response regulator
DLK06_RS08790	COG3852	Histidine kinase
DLK06_RS08815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DLK06_RS08820	COG0575	Belongs to the CDS family
DLK06_RS08855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLK06_RS08870	COG2137	regulation of response to DNA damage stimulus
DLK06_RS08880	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DLK06_RS08885	COG1011	Hydrolase
DLK06_RS08900	COG1522	sequence-specific DNA binding
DLK06_RS08910	COG1113	amino acid transport
DLK06_RS08940	COG0659	secondary active sulfate transmembrane transporter activity
DLK06_RS08960	COG3300	MHYT domain
DLK06_RS08960	COG5001	Diguanylate cyclase
DLK06_RS08975	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DLK06_RS08975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLK06_RS08975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLK06_RS08980	COG1105	Belongs to the carbohydrate kinase PfkB family
DLK06_RS08985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DLK06_RS08985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLK06_RS09005	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DLK06_RS09015	COG0024	Methionine aminopeptidase
DLK06_RS09020	COG0583	DNA-binding transcription factor activity
DLK06_RS09030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DLK06_RS09035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DLK06_RS09040	COG0517	IMP dehydrogenase activity
DLK06_RS09040	COG0516	GMP reductase activity
DLK06_RS09065	COG0552	protein localization to endoplasmic reticulum
DLK06_RS09090	COG4890	Cyd operon protein YbgT
DLK06_RS09095	COG1294	oxidase, subunit
DLK06_RS09110	COG1585	Membrane protein implicated in regulation of membrane protease activity
DLK06_RS09120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLK06_RS09135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DLK06_RS09140	COG0569	domain protein
DLK06_RS09145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DLK06_RS09175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DLK06_RS09180	COG0542	response to heat
DLK06_RS09205	COG1902	pentaerythritol trinitrate reductase activity
DLK06_RS09205	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLK06_RS09245	COG0148	phosphopyruvate hydratase activity
DLK06_RS09250	COG2323	membrane
DLK06_RS09260	COG4773	Receptor
DLK06_RS09265	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DLK06_RS09275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DLK06_RS09280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DLK06_RS09285	COG0183	Belongs to the thiolase family
DLK06_RS09290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DLK06_RS09295	COG0596	Alpha beta hydrolase
DLK06_RS09300	COG2271	Major facilitator Superfamily
DLK06_RS09305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DLK06_RS09310	COG3485	protocatechuate 3,4-dioxygenase
DLK06_RS09315	COG3485	protocatechuate 3,4-dioxygenase
DLK06_RS09320	COG0710	3-dehydroquinate dehydratase activity
DLK06_RS09325	COG3420	alginic acid biosynthetic process
DLK06_RS09335	COG4993	Dehydrogenase
DLK06_RS09345	COG2391	methyltransferase activity
DLK06_RS09360	COG1414	Transcriptional regulator
DLK06_RS09365	COG0583	DNA-binding transcription factor activity
DLK06_RS09370	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS09395	COG2814	Major facilitator Superfamily
DLK06_RS09405	COG0154	amidase activity
DLK06_RS09425	COG4638	Rieske (2fe-2S)
DLK06_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS09445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLK06_RS09455	COG3733	amine oxidase
DLK06_RS09465	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS09470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLK06_RS09475	COG0183	Belongs to the thiolase family
DLK06_RS09480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DLK06_RS09485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DLK06_RS09495	COG4829	muconolactone delta-isomerase
DLK06_RS09500	COG4948	Mandelate Racemase Muconate Lactonizing
DLK06_RS09505	COG0583	DNA-binding transcription factor activity
DLK06_RS09515	COG2186	Transcriptional regulator
DLK06_RS09535	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS09540	COG2351	hydroxyisourate hydrolase activity
DLK06_RS09545	COG2233	PERMEase
DLK06_RS09555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLK06_RS09560	COG2186	Transcriptional regulator
DLK06_RS09575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLK06_RS09585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLK06_RS09605	COG1902	pentaerythritol trinitrate reductase activity
DLK06_RS09605	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLK06_RS09610	COG4221	oxidoreductase activity
DLK06_RS09645	COG1309	transcriptional regulator
DLK06_RS09650	COG0583	DNA-binding transcription factor activity
DLK06_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS09675	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS09685	COG0318	PFAM AMP-dependent synthetase and ligase
DLK06_RS09715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLK06_RS09720	COG2259	Doxx family
DLK06_RS09735	COG4993	Dehydrogenase
DLK06_RS09770	COG0583	DNA-binding transcription factor activity
DLK06_RS09795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLK06_RS09800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DLK06_RS09820	COG2831	hemolysin activation secretion protein
DLK06_RS09830	COG4372	Transposase
DLK06_RS09900	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS09905	COG0129	dihydroxy-acid dehydratase activity
DLK06_RS09915	COG0583	DNA-binding transcription factor activity
DLK06_RS09920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DLK06_RS09930	COG2084	Dehydrogenase
DLK06_RS09945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLK06_RS09950	COG1120	ATPase activity
DLK06_RS09965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DLK06_RS10000	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DLK06_RS10045	COG1073	alpha beta
DLK06_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS10070	COG2207	Transcriptional regulator
DLK06_RS10090	COG3539	Fimbrial protein
DLK06_RS10115	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DLK06_RS10125	COG0753	catalase activity
DLK06_RS10155	COG2205	protein histidine kinase activity
DLK06_RS10160	COG0745	RESPONSE REGULATOR receiver
DLK06_RS10165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS10170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLK06_RS10225	COG1535	isochorismatase
DLK06_RS10225	COG3433	isochorismatase activity
DLK06_RS10230	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS10235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DLK06_RS10240	COG4149	molybdate abc transporter
DLK06_RS10245	COG0725	ABC transporter, periplasmic molybdate-binding protein
DLK06_RS10255	COG4638	Rieske (2fe-2S)
DLK06_RS10260	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DLK06_RS10265	COG0543	2 iron, 2 sulfur cluster binding
DLK06_RS10265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLK06_RS10280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLK06_RS10290	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS10310	COG2207	Transcriptional regulator
DLK06_RS10315	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS10330	COG0583	DNA-binding transcription factor activity
DLK06_RS10345	COG2031	fatty acid transporter
DLK06_RS10350	COG0183	Belongs to the thiolase family
DLK06_RS10355	COG0583	DNA-binding transcription factor activity
DLK06_RS10360	COG0583	DNA-binding transcription factor activity
DLK06_RS10375	COG1027	Aspartate ammonia-lyase
DLK06_RS10385	COG0477	Major facilitator Superfamily
DLK06_RS10395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLK06_RS10400	COG1733	regulation of RNA biosynthetic process
DLK06_RS10405	COG3708	Transcriptional regulator
DLK06_RS10405	COG2207	Transcriptional regulator
DLK06_RS10420	COG0730	response to heat
DLK06_RS10425	COG3453	Protein conserved in bacteria
DLK06_RS10425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLK06_RS10440	COG3781	membrane
DLK06_RS10445	COG1063	alcohol dehydrogenase
DLK06_RS10455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLK06_RS10460	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLK06_RS10465	COG0022	dehydrogenase e1 component
DLK06_RS10470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DLK06_RS10475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DLK06_RS10490	COG3706	GGDEF domain
DLK06_RS10515	COG0133	tryptophan synthase activity
DLK06_RS10525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLK06_RS10555	COG0583	DNA-binding transcription factor activity
DLK06_RS10560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLK06_RS10570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DLK06_RS10630	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLK06_RS10635	COG4773	Receptor
DLK06_RS10660	COG0730	response to heat
DLK06_RS10665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DLK06_RS10685	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DLK06_RS10715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DLK06_RS10730	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS10735	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS10740	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLK06_RS10745	COG2207	Transcriptional regulator
DLK06_RS10750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLK06_RS10755	COG0776	regulation of translation
DLK06_RS10780	COG0822	iron-sulfur transferase activity
DLK06_RS10785	COG0316	Belongs to the HesB IscA family
DLK06_RS10815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DLK06_RS10835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DLK06_RS10840	COG0702	epimerase
DLK06_RS10870	COG4172	Belongs to the ABC transporter superfamily
DLK06_RS10880	COG0601	transmembrane transport
DLK06_RS10885	COG0339	signal peptide processing
DLK06_RS10890	COG4166	transmembrane transport
DLK06_RS10935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DLK06_RS10940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DLK06_RS10955	COG2431	L-lysine efflux transmembrane transporter activity
DLK06_RS10970	COG0776	regulation of translation
DLK06_RS11035	COG0084	hydrolase, TatD family'
DLK06_RS11055	COG1663	tetraacyldisaccharide 4'-kinase activity
DLK06_RS11060	COG1132	(ABC) transporter
DLK06_RS11070	COG0811	peptide transport
DLK06_RS11075	COG1475	DNA binding
DLK06_RS11080	COG1192	Involved in chromosome partitioning
DLK06_RS11090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DLK06_RS11095	COG3178	'Phosphotransferase
DLK06_RS11105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLK06_RS11130	COG0424	maF-like protein
DLK06_RS11135	COG2850	peptidyl-arginine hydroxylation
DLK06_RS11145	COG0640	Transcriptional regulator
DLK06_RS11155	COG3619	membrane
DLK06_RS11160	COG3122	Protein conserved in bacteria
DLK06_RS11165	COG1132	(ABC) transporter
DLK06_RS11185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DLK06_RS11190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DLK06_RS11200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DLK06_RS11200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DLK06_RS11200	COG0506	proline dehydrogenase activity
DLK06_RS11205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DLK06_RS11220	COG3698	Phosphodiester glycosidase
DLK06_RS11230	COG2353	YceI-like domain
DLK06_RS11240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DLK06_RS11285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DLK06_RS11285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DLK06_RS11310	COG3539	Fimbrial protein
DLK06_RS11345	COG0583	DNA-binding transcription factor activity
DLK06_RS11350	COG0697	spore germination
DLK06_RS11360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DLK06_RS11365	COG4372	Transposase
DLK06_RS11385	COG0583	DNA-binding transcription factor activity
DLK06_RS11400	COG1309	transcriptional regulator
DLK06_RS11415	COG1522	sequence-specific DNA binding
DLK06_RS11425	COG1126	abc transporter atp-binding protein
DLK06_RS11430	COG0765	amino acid transport
DLK06_RS11435	COG0765	amino acid transport
DLK06_RS11465	COG1464	Belongs to the NlpA lipoprotein family
DLK06_RS11475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DLK06_RS11480	COG2011	ABC-type metal ion transport system permease component
DLK06_RS11485	COG0012	GTP binding
DLK06_RS11510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DLK06_RS11545	COG2207	Transcriptional regulator
DLK06_RS11545	COG1917	Cupin 2, conserved barrel domain protein
DLK06_RS11550	COG0386	Belongs to the glutathione peroxidase family
DLK06_RS11560	COG0436	Aminotransferase
DLK06_RS11565	COG1301	dicarboxylic acid transport
DLK06_RS11600	COG3634	alkyl hydroperoxide reductase activity
DLK06_RS11615	COG0583	DNA-binding transcription factor activity
DLK06_RS11620	COG0431	NADPH-dependent FMN reductase
DLK06_RS11625	COG0798	PFAM Bile acid sodium symporter
DLK06_RS11635	COG0640	Transcriptional regulator
DLK06_RS11650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DLK06_RS11660	COG0583	DNA-binding transcription factor activity
DLK06_RS11670	COG1953	Uracil, thiamine, allantoin
DLK06_RS11680	COG2175	clavaminate synthase activity
DLK06_RS11685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLK06_RS11690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DLK06_RS11695	COG4521	taurine ABC transporter
DLK06_RS11705	COG0477	Major facilitator Superfamily
DLK06_RS11730	COG1271	oxidase subunit
DLK06_RS11735	COG1294	oxidase, subunit
DLK06_RS11745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLK06_RS11765	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DLK06_RS11785	COG3052	prosthetic group binding
DLK06_RS11790	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DLK06_RS11815	COG1346	cytolysis
DLK06_RS11825	COG0583	DNA-binding transcription factor activity
DLK06_RS11830	COG0625	glutathione transferase activity
DLK06_RS11835	COG0625	glutathione transferase activity
DLK06_RS11855	COG0583	DNA-binding transcription factor activity
DLK06_RS11860	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS11870	COG1045	serine acetyltransferase
DLK06_RS11875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLK06_RS11880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DLK06_RS11885	COG1280	lysine exporter protein (LysE YggA)
DLK06_RS11895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK06_RS11900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK06_RS11910	COG0765	amino acid transport
DLK06_RS11935	COG0784	Response regulator, receiver
DLK06_RS11935	COG2205	protein histidine kinase activity
DLK06_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS12020	COG0583	DNA-binding transcription factor activity
DLK06_RS12035	COG2814	Major facilitator Superfamily
DLK06_RS12050	COG0318	PFAM AMP-dependent synthetase and ligase
DLK06_RS12055	COG1309	transcriptional regulator
DLK06_RS12060	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS12065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DLK06_RS12070	COG1024	Enoyl-CoA hydratase
DLK06_RS12075	COG4770	biotin carboxylase activity
DLK06_RS12085	COG0583	DNA-binding transcription factor activity
DLK06_RS12100	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS12110	COG2814	Major facilitator Superfamily
DLK06_RS12120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DLK06_RS12125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DLK06_RS12130	COG2814	Major facilitator Superfamily
DLK06_RS12135	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS12140	COG1024	Enoyl-CoA hydratase
DLK06_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLK06_RS12155	COG0183	Belongs to the thiolase family
DLK06_RS12165	COG2814	Major facilitator Superfamily
DLK06_RS12175	COG1024	Enoyl-CoA hydratase
DLK06_RS12190	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS12195	COG2814	Major facilitator Superfamily
DLK06_RS12200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DLK06_RS12205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DLK06_RS12220	COG3842	ATPase activity
DLK06_RS12225	COG1840	ABC-type Fe3 transport system, periplasmic component
DLK06_RS12240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLK06_RS12245	COG1414	Transcriptional regulator
DLK06_RS12255	COG0583	DNA-binding transcription factor activity
DLK06_RS12295	COG2050	protein possibly involved in aromatic compounds catabolism
DLK06_RS12305	COG3327	negative regulation of DNA-templated transcription, initiation
DLK06_RS12310	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DLK06_RS12315	COG0183	Belongs to the thiolase family
DLK06_RS12320	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLK06_RS12325	COG1024	Enoyl-CoA hydratase
DLK06_RS12330	COG1024	Enoyl-CoA hydratase
DLK06_RS12335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLK06_RS12340	COG2151	metal-sulfur cluster biosynthetic enzyme
DLK06_RS12345	COG3396	Phenylacetate-CoA oxygenase
DLK06_RS12350	COG3460	Phenylacetate-CoA oxygenase
DLK06_RS12355	COG3396	Phenylacetate-CoA oxygenase
DLK06_RS12360	COG2030	dehydratase
DLK06_RS12360	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS12365	COG1760	l-serine dehydratase
DLK06_RS12385	COG0789	Transcriptional regulator
DLK06_RS12395	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DLK06_RS12420	COG0590	tRNA wobble adenosine to inosine editing
DLK06_RS12425	COG0666	response to abiotic stimulus
DLK06_RS12520	COG1116	anion transmembrane transporter activity
DLK06_RS12525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLK06_RS12535	COG0864	Transcriptional regulator
DLK06_RS12545	COG1733	regulation of RNA biosynthetic process
DLK06_RS12550	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLK06_RS12555	COG0439	Biotin carboxylase
DLK06_RS12570	COG1063	alcohol dehydrogenase
DLK06_RS12575	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLK06_RS12610	COG3210	domain, Protein
DLK06_RS12615	COG2831	hemolysin activation secretion protein
DLK06_RS12620	COG0038	chloride channel
DLK06_RS12625	COG4770	biotin carboxylase activity
DLK06_RS12645	COG1914	H( )-stimulated, divalent metal cation uptake system
DLK06_RS12650	COG0583	DNA-binding transcription factor activity
DLK06_RS12660	COG1595	DNA-templated transcription, initiation
DLK06_RS12670	COG3220	belongs to the UPF0276 family
DLK06_RS12725	COG0702	epimerase
DLK06_RS12730	COG1733	regulation of RNA biosynthetic process
DLK06_RS12750	COG1051	belongs to the nudix hydrolase family
DLK06_RS12790	COG3038	cytochrome b561
DLK06_RS12795	COG0753	catalase activity
DLK06_RS12810	COG1469	GTP cyclohydrolase I activity
DLK06_RS12815	COG4451	ribulose bisphosphate carboxylase, small
DLK06_RS12815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DLK06_RS12820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DLK06_RS12835	COG1522	sequence-specific DNA binding
DLK06_RS12840	COG0531	amino acid
DLK06_RS12845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DLK06_RS12860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLK06_RS12875	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DLK06_RS12885	COG4122	O-methyltransferase activity
DLK06_RS12915	COG1538	Outer membrane efflux protein
DLK06_RS12920	COG1137	ATPase activity
DLK06_RS12925	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DLK06_RS12935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DLK06_RS13075	COG5484	DNA packaging
DLK06_RS13075	COG3728	DNA packaging
DLK06_RS13155	COG5377	YqaJ viral recombinase family
DLK06_RS13165	COG0210	DNA helicase
DLK06_RS13245	COG2814	Major facilitator Superfamily
DLK06_RS13255	COG0668	transmembrane transport
DLK06_RS13340	COG2226	methyltransferase
DLK06_RS13365	COG1278	Cold shock
DLK06_RS13370	COG1560	Kdo2-lipid A biosynthetic process
DLK06_RS13375	COG1280	lysine exporter protein (LysE YggA)
DLK06_RS13410	COG1570	exodeoxyribonuclease VII activity
DLK06_RS13460	COG0583	DNA-binding transcription factor activity
DLK06_RS13470	COG4638	Rieske (2fe-2S)
DLK06_RS13475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DLK06_RS13480	COG0633	Ferredoxin
DLK06_RS13480	COG0543	2 iron, 2 sulfur cluster binding
DLK06_RS13485	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS13490	COG3135	benzoate transporter
DLK06_RS13495	COG2814	Major facilitator Superfamily
DLK06_RS13510	COG1643	Atp-dependent helicase
DLK06_RS13535	COG3634	alkyl hydroperoxide reductase activity
DLK06_RS13555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DLK06_RS13560	COG0625	glutathione transferase activity
DLK06_RS13570	COG2885	chlorophyll binding
DLK06_RS13605	COG0542	response to heat
DLK06_RS13620	COG1765	OsmC-like protein
DLK06_RS13635	COG0667	Aldo Keto reductase
DLK06_RS13650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DLK06_RS13665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DLK06_RS13675	COG0582	viral genome integration into host DNA
DLK06_RS13750	COG0741	lytic transglycosylase activity
DLK06_RS13750	COG1196	nuclear chromosome segregation
DLK06_RS13750	COG0739	heme binding
DLK06_RS13760	COG1598	PFAM Uncharacterised protein family UPF0150
DLK06_RS13855	COG5410	chromosome segregation
DLK06_RS14010	COG0527	aspartate kinase activity
DLK06_RS14020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DLK06_RS14030	COG3038	cytochrome b561
DLK06_RS14035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DLK06_RS14040	COG2252	PERMEase
DLK06_RS14050	COG1741	Belongs to the pirin family
DLK06_RS14055	COG1309	transcriptional regulator
DLK06_RS14070	COG2072	flavoprotein involved in K transport
DLK06_RS14075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DLK06_RS14080	COG0583	DNA-binding transcription factor activity
DLK06_RS14095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DLK06_RS14125	COG1944	ATP diphosphatase activity
DLK06_RS14145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DLK06_RS14160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLK06_RS14175	COG2814	Major facilitator Superfamily
DLK06_RS14180	COG1024	Enoyl-CoA hydratase
DLK06_RS14185	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS14195	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS14220	COG2186	Transcriptional regulator
DLK06_RS14225	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS14235	COG4948	Mandelate Racemase Muconate Lactonizing
DLK06_RS14240	COG2271	Major facilitator Superfamily
DLK06_RS14245	COG2721	sulfolactate sulfo-lyase activity
DLK06_RS14250	COG0697	spore germination
DLK06_RS14280	COG1113	amino acid transport
DLK06_RS14300	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS14320	COG0531	amino acid
DLK06_RS14330	COG1113	amino acid transport
DLK06_RS14365	COG4269	membrane
DLK06_RS14380	COG0582	viral genome integration into host DNA
DLK06_RS14435	COG2826	transposase and inactivated derivatives, IS30 family
DLK06_RS14485	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLK06_RS14485	COG1902	pentaerythritol trinitrate reductase activity
DLK06_RS14495	COG2203	Gaf domain
DLK06_RS14495	COG4251	negative regulation of phosphorylation
DLK06_RS14495	COG5001	Diguanylate cyclase
DLK06_RS14495	COG3706	GGDEF domain
DLK06_RS14505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLK06_RS14525	COG4172	Belongs to the ABC transporter superfamily
DLK06_RS14530	COG4239	(ABC) transporter, permease
DLK06_RS14535	COG4174	ABC transporter (Permease)
DLK06_RS14540	COG4166	transmembrane transport
DLK06_RS14545	COG1388	LysM domain
DLK06_RS14545	COG0741	lytic transglycosylase activity
DLK06_RS14545	COG1388	LysM domain
DLK06_RS14545	COG0741	lytic transglycosylase activity
DLK06_RS14590	COG0583	DNA-binding transcription factor activity
DLK06_RS14595	COG1279	arginine transmembrane transporter activity
DLK06_RS14615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLK06_RS14620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLK06_RS14625	COG0006	proline dipeptidase activity
DLK06_RS14665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DLK06_RS14680	COG3384	dioxygenase
DLK06_RS14690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DLK06_RS14695	COG2878	Part of a membrane complex involved in electron transport
DLK06_RS14700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DLK06_RS14725	COG0768	penicillin binding
DLK06_RS14730	COG0742	ribosomal rna small subunit methyltransferase
DLK06_RS14745	COG0830	nickel cation binding
DLK06_RS14755	COG0804	urea catabolic process
DLK06_RS14780	COG3015	lipoprotein NlpE involved in copper resistance
DLK06_RS14795	COG1253	flavin adenine dinucleotide binding
DLK06_RS14800	COG2851	Citrate transporter
DLK06_RS14855	COG1773	rubredoxin
DLK06_RS14860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DLK06_RS14865	COG0596	Alpha beta hydrolase
DLK06_RS14870	COG0583	DNA-binding transcription factor activity
DLK06_RS14900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DLK06_RS14905	COG4181	ATPase activity
DLK06_RS14950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DLK06_RS14970	COG0306	phosphate transporter
DLK06_RS14985	COG3958	Transketolase
DLK06_RS14990	COG3959	Transketolase, thiamine diphosphate binding domain
DLK06_RS14995	COG2271	Major facilitator Superfamily
DLK06_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS15005	COG0583	DNA-binding transcription factor activity
DLK06_RS15025	COG2223	nitrite transmembrane transporter activity
DLK06_RS15030	COG2207	Transcriptional regulator
DLK06_RS15035	COG2066	Belongs to the glutaminase family
DLK06_RS15040	COG0242	peptide deformylase activity
DLK06_RS15045	COG0477	Major facilitator Superfamily
DLK06_RS15055	COG0028	Belongs to the TPP enzyme family
DLK06_RS15070	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS15075	COG2267	carboxylic ester hydrolase activity
DLK06_RS15085	COG2271	Major facilitator Superfamily
DLK06_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS15120	COG1414	Transcriptional regulator
DLK06_RS15145	COG1215	transferase activity, transferring glycosyl groups
DLK06_RS15150	COG1649	PFAM Uncharacterised BCR, COG1649
DLK06_RS15150	COG0726	polysaccharide deacetylase
DLK06_RS15160	COG4681	YaeQ
DLK06_RS15170	COG0523	cobalamin synthesis protein
DLK06_RS15185	COG1607	acyl-coa hydrolase
DLK06_RS15195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DLK06_RS15200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DLK06_RS15205	COG1309	transcriptional regulator
DLK06_RS15235	COG0405	Gamma-glutamyltransferase
DLK06_RS15240	COG2814	Major facilitator Superfamily
DLK06_RS15250	COG2050	protein possibly involved in aromatic compounds catabolism
DLK06_RS15265	COG1090	epimerase
DLK06_RS15285	COG0420	3'-5' exonuclease activity
DLK06_RS15310	COG0735	belongs to the Fur family
DLK06_RS15315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DLK06_RS15320	COG2914	Belongs to the UPF0125 (RnfH) family
DLK06_RS15340	COG0121	glutamine amidotransferase
DLK06_RS15355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DLK06_RS15365	COG0210	DNA helicase
DLK06_RS15370	COG2885	chlorophyll binding
DLK06_RS15375	COG0204	Acyl-transferase
DLK06_RS15390	COG2894	cell division
DLK06_RS15405	COG1280	lysine exporter protein (LysE YggA)
DLK06_RS15410	COG1674	ftsk spoiiie
DLK06_RS15415	COG0492	ferredoxin-NADP+ reductase activity
DLK06_RS15420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DLK06_RS15430	COG0456	acetyltransferase
DLK06_RS15455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DLK06_RS15460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DLK06_RS15470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DLK06_RS15485	COG1981	membrane
DLK06_RS15495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DLK06_RS15495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLK06_RS15515	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS15520	COG4638	Rieske (2fe-2S)
DLK06_RS15525	COG0657	acetylesterase activity
DLK06_RS15535	COG0473	3-isopropylmalate dehydrogenase activity
DLK06_RS15540	COG0583	DNA-binding transcription factor activity
DLK06_RS15560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLK06_RS15570	COG0582	viral genome integration into host DNA
DLK06_RS15940	COG0358	DNA primase activity
DLK06_RS15955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DLK06_RS15985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DLK06_RS16015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLK06_RS16025	COG0351	phosphomethylpyrimidine kinase
DLK06_RS16025	COG0352	thiamine-phosphate diphosphorylase activity
DLK06_RS16025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DLK06_RS16030	COG1652	LysM domain
DLK06_RS16055	COG1399	metal-binding, possibly nucleic acid-binding protein
DLK06_RS16060	COG3101	peptidyl-lysine hydroxylation
DLK06_RS16065	COG0009	L-threonylcarbamoyladenylate synthase
DLK06_RS16070	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DLK06_RS16075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DLK06_RS16090	COG4106	trans-aconitate 2-methyltransferase activity
DLK06_RS16105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLK06_RS16105	COG2226	methyltransferase
DLK06_RS16105	COG0596	Alpha beta hydrolase
DLK06_RS16115	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DLK06_RS16120	COG2223	nitrite transmembrane transporter activity
DLK06_RS16205	COG3621	Patatin-like phospholipase
DLK06_RS16225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DLK06_RS16235	COG1061	Type III restriction enzyme res subunit
DLK06_RS16240	COG1002	Type II restriction enzyme, methylase subunits
DLK06_RS16245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DLK06_RS16260	COG1196	nuclear chromosome segregation
DLK06_RS16270	COG0730	response to heat
DLK06_RS16285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DLK06_RS16295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLK06_RS16310	COG4372	Transposase
DLK06_RS16360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DLK06_RS16365	COG0489	protein tyrosine kinase activity
DLK06_RS16375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLK06_RS16375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLK06_RS16410	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DLK06_RS16415	COG2081	HI0933 family
DLK06_RS16425	COG0668	transmembrane transport
DLK06_RS16445	COG0583	DNA-binding transcription factor activity
DLK06_RS16465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLK06_RS16470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DLK06_RS16500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DLK06_RS16525	COG2199	diguanylate cyclase activity
DLK06_RS16540	COG0745	RESPONSE REGULATOR receiver
DLK06_RS16555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLK06_RS16560	COG0384	phenazine biosynthesis protein PhzF
DLK06_RS16620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLK06_RS16635	COG0583	DNA-binding transcription factor activity
DLK06_RS16685	COG0583	DNA-binding transcription factor activity
DLK06_RS16705	COG0583	DNA-binding transcription factor activity
DLK06_RS16710	COG1053	succinate dehydrogenase
DLK06_RS16725	COG1309	transcriptional regulator
DLK06_RS16735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DLK06_RS16740	COG2814	Major facilitator Superfamily
DLK06_RS16745	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS16750	COG0583	DNA-binding transcription factor activity
DLK06_RS16755	COG1063	alcohol dehydrogenase
DLK06_RS16770	COG0582	viral genome integration into host DNA
DLK06_RS16775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLK06_RS16800	COG1122	ATPase activity
DLK06_RS16840	COG2826	transposase and inactivated derivatives, IS30 family
DLK06_RS16955	COG3409	Peptidoglycan-binding domain 1 protein
DLK06_RS16955	COG0860	N-Acetylmuramoyl-L-alanine amidase
DLK06_RS17000	COG4695	Portal protein
DLK06_RS17040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DLK06_RS17045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DLK06_RS17050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DLK06_RS17070	COG2132	Multicopper oxidase
DLK06_RS17080	COG0561	phosphatase activity
DLK06_RS17085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DLK06_RS17095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DLK06_RS17110	COG1214	PFAM Peptidase M22, glycoprotease
DLK06_RS17170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DLK06_RS17175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DLK06_RS17180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DLK06_RS17240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLK06_RS17250	COG1846	Transcriptional regulator
DLK06_RS17255	COG1764	response to oxidative stress
DLK06_RS17295	COG0037	tRNA processing
DLK06_RS17305	COG0248	Ppx GppA phosphatase
DLK06_RS17335	COG0072	phenylalanine-tRNA ligase activity
DLK06_RS17365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DLK06_RS17380	COG1238	metal cluster binding
DLK06_RS17385	COG0625	glutathione transferase activity
DLK06_RS17405	COG0318	PFAM AMP-dependent synthetase and ligase
DLK06_RS17410	COG3028	Belongs to the UPF0307 family
DLK06_RS17415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLK06_RS17435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DLK06_RS17440	COG0617	tRNA 3'-terminal CCA addition
DLK06_RS17445	COG1555	photosystem II stabilization
DLK06_RS17450	COG3956	TIGRFAM MazG family protein
DLK06_RS17460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLK06_RS17475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DLK06_RS17480	COG2205	protein histidine kinase activity
DLK06_RS17480	COG0784	Response regulator, receiver
DLK06_RS17480	COG5002	protein histidine kinase activity
DLK06_RS17485	COG1024	Enoyl-CoA hydratase
DLK06_RS17490	COG2084	Dehydrogenase
DLK06_RS17495	COG3622	Belongs to the hyi family
DLK06_RS17525	COG0697	spore germination
DLK06_RS17535	COG2814	Major facilitator Superfamily
DLK06_RS17540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLK06_RS17550	COG0583	DNA-binding transcription factor activity
DLK06_RS17560	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DLK06_RS17575	COG0084	hydrolase, TatD family'
DLK06_RS17590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DLK06_RS17605	COG1674	ftsk spoiiie
DLK06_RS17625	COG4372	Transposase
DLK06_RS17660	COG2233	PERMEase
DLK06_RS17870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DLK06_RS17875	COG0440	acetolactate synthase activity
DLK06_RS17880	COG0028	Belongs to the TPP enzyme family
DLK06_RS17900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLK06_RS17905	COG0577	efflux transmembrane transporter activity
DLK06_RS17905	COG1136	(ABC) transporter
DLK06_RS17925	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DLK06_RS17930	COG1162	GTPase activity
DLK06_RS17940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DLK06_RS17960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DLK06_RS17980	COG1426	Protein conserved in bacteria
DLK06_RS18015	COG0793	Belongs to the peptidase S41A family
DLK06_RS18030	COG2267	carboxylic ester hydrolase activity
DLK06_RS18040	COG1012	belongs to the aldehyde dehydrogenase family
DLK06_RS18045	COG3265	gluconokinase activity
DLK06_RS18055	COG0800	Aldolase
DLK06_RS18070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DLK06_RS18075	COG0280	phosphate acetyltransferase
DLK06_RS18075	COG0857	belongs to the CobB CobQ family
DLK06_RS18080	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DLK06_RS18080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DLK06_RS18100	COG0740	serine-type endopeptidase activity
DLK06_RS18110	COG4774	siderophore transport
DLK06_RS18120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DLK06_RS18130	COG2813	Specifically methylates the guanine in position
DLK06_RS18130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLK06_RS18230	COG0788	formyltetrahydrofolate deformylase activity
DLK06_RS18255	COG4651	solute:proton antiporter activity
DLK06_RS18255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLK06_RS18275	COG0724	RNA recognition motif
DLK06_RS18280	COG0210	DNA helicase
DLK06_RS18305	COG1733	regulation of RNA biosynthetic process
DLK06_RS18310	COG0604	alcohol dehydrogenase
DLK06_RS18315	COG2900	Belongs to the SlyX family
DLK06_RS18320	COG0488	(ABC) transporter
DLK06_RS18330	COG1560	Kdo2-lipid A biosynthetic process
DLK06_RS18340	COG1301	dicarboxylic acid transport
DLK06_RS18395	COG0473	3-isopropylmalate dehydrogenase activity
DLK06_RS18420	COG0583	DNA-binding transcription factor activity
DLK06_RS18460	COG0583	DNA-binding transcription factor activity
DLK06_RS18470	COG0625	glutathione transferase activity
DLK06_RS18475	COG2378	regulation of single-species biofilm formation
DLK06_RS18480	COG0546	phosphoglycolate phosphatase activity
DLK06_RS18495	COG1530	ribonuclease E activity
DLK06_RS18500	COG0318	PFAM AMP-dependent synthetase and ligase
DLK06_RS18515	COG0583	DNA-binding transcription factor activity
DLK06_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS18525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLK06_RS18535	COG0534	Mate efflux family protein
DLK06_RS18550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DLK06_RS18575	COG0493	'glutamate synthase
DLK06_RS18585	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DLK06_RS18590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLK06_RS18605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DLK06_RS18615	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DLK06_RS18615	COG0644	oxidoreductase
DLK06_RS18630	COG4535	Mg2 and Co2 transporter CorC
DLK06_RS18680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DLK06_RS18690	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DLK06_RS18700	COG0484	heat shock protein binding
DLK06_RS18705	COG0789	Transcriptional regulator
DLK06_RS18710	COG0598	Magnesium transport protein CorA
DLK06_RS18715	COG1185	polyribonucleotide nucleotidyltransferase activity
DLK06_RS18725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DLK06_RS18730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DLK06_RS18735	COG1074	ATP-dependent DNA helicase activity
DLK06_RS18740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DLK06_RS18760	COG2226	methyltransferase
DLK06_RS18775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLK06_RS18785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DLK06_RS18800	COG2111	Na H antiporter
DLK06_RS18800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DLK06_RS18805	COG1006	Multisubunit Na H antiporter MnhC subunit
DLK06_RS18810	COG0651	ATP synthesis coupled electron transport
DLK06_RS18815	COG1863	multisubunit Na H antiporter MnhE subunit
DLK06_RS18820	COG2212	antiporter activity
DLK06_RS18825	COG1320	monovalent cation:proton antiporter activity
DLK06_RS18830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DLK06_RS18840	COG0195	Participates in both transcription termination and antitermination
DLK06_RS18890	COG0237	dephospho-CoA kinase activity
DLK06_RS18900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLK06_RS18915	COG0497	DNA recombination
DLK06_RS18925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DLK06_RS18960	COG2169	Transcriptional regulator
DLK06_RS18960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DLK06_RS18965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DLK06_RS19045	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DLK06_RS19060	COG0326	Molecular chaperone. Has ATPase activity
DLK06_RS19080	COG2056	Na+-H+ antiporter family
DLK06_RS19150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DLK06_RS19180	COG0546	phosphoglycolate phosphatase activity
DLK06_RS19185	COG1716	ATPase activity
DLK06_RS19230	COG0181	hydroxymethylbilane synthase activity
DLK06_RS19240	COG3275	phosphorelay sensor kinase activity
DLK06_RS19260	COG1538	Outer membrane efflux protein
DLK06_RS19270	COG0697	spore germination
DLK06_RS19290	COG0494	nUDIX hydrolase
DLK06_RS19295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DLK06_RS19300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DLK06_RS19305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLK06_RS19310	COG0772	Belongs to the SEDS family
DLK06_RS19335	COG4974	Belongs to the 'phage' integrase family
DLK06_RS19340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLK06_RS19350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DLK06_RS19360	COG2197	response regulator
DLK06_RS19375	COG0793	Belongs to the peptidase S41A family
DLK06_RS19380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DLK06_RS19385	COG0795	lipopolysaccharide-transporting ATPase activity
DLK06_RS19425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DLK06_RS19425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DLK06_RS19435	COG0004	ammonium transporteR
DLK06_RS19440	COG0347	Belongs to the P(II) protein family
DLK06_RS19450	COG0606	chelatase, subunit chli
DLK06_RS19455	COG0431	NADPH-dependent FMN reductase
DLK06_RS19460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLK06_RS19465	COG0235	Class ii aldolase
DLK06_RS19470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLK06_RS19490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DLK06_RS19505	COG0318	PFAM AMP-dependent synthetase and ligase
DLK06_RS19515	COG0477	Major facilitator Superfamily
DLK06_RS19520	COG2860	membrane
DLK06_RS19530	COG1253	flavin adenine dinucleotide binding
DLK06_RS19540	COG2814	Major facilitator Superfamily
DLK06_RS19550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DLK06_RS19590	COG0655	NAD(P)H dehydrogenase (quinone) activity
DLK06_RS19605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DLK06_RS19635	COG1309	transcriptional regulator
DLK06_RS19670	COG0758	DNA mediated transformation
DLK06_RS19680	COG0697	spore germination
DLK06_RS19685	COG1309	transcriptional regulator
DLK06_RS19700	COG0386	Belongs to the glutathione peroxidase family
DLK06_RS19715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DLK06_RS19725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DLK06_RS19765	COG1121	(ABC) transporter
DLK06_RS19770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DLK06_RS19775	COG1280	lysine exporter protein (LysE YggA)
DLK06_RS19780	COG2837	iron assimilation
DLK06_RS19785	COG0281	malic enzyme
DLK06_RS19830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLK06_RS19830	COG0519	Catalyzes the synthesis of GMP from XMP
DLK06_RS19835	COG4399	Belongs to the UPF0754 family
DLK06_RS19840	COG2259	Doxx family
DLK06_RS19845	COG0586	Pfam SNARE associated Golgi protein
DLK06_RS19860	COG1192	Involved in chromosome partitioning
DLK06_RS19870	COG0271	Belongs to the BolA IbaG family
DLK06_RS19910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DLK06_RS19910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DLK06_RS19910	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DLK06_RS19910	COG3321	synthase
DLK06_RS19915	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS19920	COG0318	PFAM AMP-dependent synthetase and ligase
DLK06_RS19925	COG2197	response regulator
DLK06_RS19940	COG3916	Acyl-homoserine-lactone synthase
DLK06_RS19945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLK06_RS19955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLK06_RS19960	COG1113	amino acid transport
DLK06_RS19965	COG0697	spore germination
DLK06_RS19970	COG0477	Major facilitator Superfamily
DLK06_RS19975	COG1024	Enoyl-CoA hydratase
DLK06_RS19980	COG1024	Enoyl-CoA hydratase
DLK06_RS19985	COG1960	acyl-CoA dehydrogenase activity
DLK06_RS19990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLK06_RS20010	COG1113	amino acid transport
DLK06_RS20015	COG1113	amino acid transport
DLK06_RS20020	COG0251	oxidation-reduction process
DLK06_RS20060	COG0564	pseudouridine synthase activity
DLK06_RS20135	COG1051	belongs to the nudix hydrolase family
DLK06_RS20160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DLK06_RS20175	COG1802	Transcriptional regulator
DLK06_RS20185	COG1448	Aminotransferase
DLK06_RS20190	COG0277	FAD linked oxidase domain protein
DLK06_RS20200	COG2186	Transcriptional regulator
DLK06_RS20210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DLK06_RS20225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DLK06_RS20230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DLK06_RS20265	COG1091	dTDP-4-dehydrorhamnose reductase activity
DLK06_RS20275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DLK06_RS20295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DLK06_RS20325	COG0728	peptidoglycan biosynthetic process
DLK06_RS20330	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLK06_RS20385	COG0546	phosphoglycolate phosphatase activity
DLK06_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
DLK06_RS20420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DLK06_RS20420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DLK06_RS20425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLK06_RS20430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLK06_RS20435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLK06_RS20445	COG1116	anion transmembrane transporter activity
DLK06_RS20450	COG1309	transcriptional regulator
DLK06_RS20455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DLK06_RS20465	COG0196	riboflavin kinase activity
DLK06_RS20470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DLK06_RS20480	COG1047	Peptidyl-prolyl cis-trans
DLK06_RS20520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DLK06_RS20525	COG0657	acetylesterase activity
DLK06_RS20575	COG2951	lytic endotransglycosylase activity
DLK06_RS20580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DLK06_RS20595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DLK06_RS20605	COG0671	phosphoesterase, PA-phosphatase related
DLK06_RS20610	COG0861	Integral membrane protein TerC family
DLK06_RS20620	COG0754	glutathionylspermidine amidase activity
DLK06_RS20630	COG0402	S-adenosylhomocysteine deaminase activity
DLK06_RS20645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLK06_RS20650	COG1230	cation diffusion facilitator family transporter
DLK06_RS20665	COG0706	membrane insertase activity
DLK06_RS20690	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DLK06_RS20855	COG0789	Transcriptional regulator
DLK06_RS20905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DLK06_RS20980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLK06_RS21015	COG0582	viral genome integration into host DNA
DLK06_RS21030	COG2130	NADP-dependent
DLK06_RS21035	COG1309	transcriptional regulator
DLK06_RS21055	COG1979	alcohol dehydrogenase
DLK06_RS21070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DLK06_RS21100	COG0477	Major facilitator Superfamily
DLK06_RS21105	COG0697	spore germination
DLK06_RS21115	COG3321	synthase
DLK06_RS21115	COG0604	alcohol dehydrogenase
DLK06_RS21120	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DLK06_RS21130	COG3328	transposase activity
DLK06_RS21160	COG3657	addiction module killer protein
DLK06_RS21165	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DLK06_RS21175	COG4683	PFAM Phage derived protein Gp49-like (DUF891)