locus-tag	class	description
C6N19_RS00010	COG1979	alcohol dehydrogenase
C6N19_RS00025	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C6N19_RS00055	COG0477	Major facilitator Superfamily
C6N19_RS00060	COG0697	spore germination
C6N19_RS00070	COG3321	synthase
C6N19_RS00070	COG0604	alcohol dehydrogenase
C6N19_RS00075	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C6N19_RS00080	COG0583	DNA-binding transcription factor activity
C6N19_RS00085	COG4221	oxidoreductase activity
C6N19_RS00130	COG3077	Addiction module antitoxin, RelB DinJ family
C6N19_RS00150	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C6N19_RS00180	COG2184	nucleotidyltransferase activity
C6N19_RS00215	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C6N19_RS00310	COG1785	Belongs to the alkaline phosphatase family
C6N19_RS00315	COG1475	DNA binding
C6N19_RS00320	COG1192	Involved in chromosome partitioning
C6N19_RS00350	COG0604	alcohol dehydrogenase
C6N19_RS00380	COG0582	viral genome integration into host DNA
C6N19_RS00395	COG2130	NADP-dependent
C6N19_RS00400	COG1309	transcriptional regulator
C6N19_RS00410	COG1902	pentaerythritol trinitrate reductase activity
C6N19_RS00440	COG3328	transposase activity
C6N19_RS00560	COG3077	Addiction module antitoxin, RelB DinJ family
C6N19_RS00590	COG1660	Displays ATPase and GTPase activities
C6N19_RS00625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6N19_RS00690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N19_RS00830	COG2184	nucleotidyltransferase activity
C6N19_RS00845	COG2184	nucleotidyltransferase activity
C6N19_RS00880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6N19_RS00920	COG0582	viral genome integration into host DNA
C6N19_RS00945	COG3621	Patatin-like phospholipase
C6N19_RS00985	COG1570	exodeoxyribonuclease VII activity
C6N19_RS00995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N19_RS01010	COG3328	transposase activity
C6N19_RS01015	COG3173	Aminoglycoside phosphotransferase
C6N19_RS01020	COG0488	(ABC) transporter
C6N19_RS01040	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N19_RS01045	COG3657	addiction module killer protein
C6N19_RS01100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6N19_RS01125	COG0592	DNA-directed DNA polymerase activity
C6N19_RS01135	COG0187	DNA topoisomerase II activity
C6N19_RS01150	COG0488	(ABC) transporter
C6N19_RS01175	COG0596	Alpha beta hydrolase
C6N19_RS01180	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C6N19_RS01185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C6N19_RS01220	COG0625	glutathione transferase activity
C6N19_RS01230	COG0733	neurotransmitter:sodium symporter activity
C6N19_RS01270	COG2233	PERMEase
C6N19_RS01285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS01320	COG2814	Major facilitator Superfamily
C6N19_RS01325	COG0656	L-ascorbic acid biosynthetic process
C6N19_RS01330	COG0583	DNA-binding transcription factor activity
C6N19_RS01345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS01350	COG1064	alcohol dehydrogenase
C6N19_RS01355	COG2818	Glycosylase
C6N19_RS01370	COG1194	a g-specific adenine glycosylase
C6N19_RS01385	COG5487	UPF0391 membrane protein
C6N19_RS01390	COG2983	Belongs to the UPF0260 family
C6N19_RS01395	COG2133	pyrroloquinoline quinone binding
C6N19_RS01400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6N19_RS01405	COG2116	formate transmembrane transporter activity
C6N19_RS01425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N19_RS01430	COG1335	isochorismatase
C6N19_RS01435	COG0385	Bile acid
C6N19_RS01440	COG0534	Mate efflux family protein
C6N19_RS01445	COG1683	Conserved Protein
C6N19_RS01460	COG0346	lactoylglutathione lyase activity
C6N19_RS01465	COG0625	glutathione transferase activity
C6N19_RS01475	COG1113	amino acid transport
C6N19_RS01485	COG0523	cobalamin synthesis protein
C6N19_RS01495	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS01505	COG2188	Transcriptional regulator
C6N19_RS01535	COG0010	Belongs to the arginase family
C6N19_RS01575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6N19_RS01585	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6N19_RS01590	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C6N19_RS01695	COG0534	Mate efflux family protein
C6N19_RS01700	COG0436	Aminotransferase
C6N19_RS01705	COG2733	membrane
C6N19_RS01720	COG2918	glutathione biosynthetic process
C6N19_RS01765	COG3150	esterase
C6N19_RS01775	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
C6N19_RS01785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N19_RS01795	COG2233	PERMEase
C6N19_RS01800	COG2351	hydroxyisourate hydrolase activity
C6N19_RS01835	COG3706	GGDEF domain
C6N19_RS01850	COG1393	Belongs to the ArsC family
C6N19_RS01855	COG0708	Exodeoxyribonuclease III
C6N19_RS01875	COG0189	ligase activity
C6N19_RS01895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6N19_RS01905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6N19_RS01920	COG4942	peptidase
C6N19_RS01930	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N19_RS01940	COG2119	membrane
C6N19_RS01945	COG4774	siderophore transport
C6N19_RS01950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N19_RS01950	COG0426	domain, Protein
C6N19_RS01970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6N19_RS01990	COG1902	pentaerythritol trinitrate reductase activity
C6N19_RS01995	COG1519	Transferase
C6N19_RS02000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N19_RS02005	COG0668	transmembrane transport
C6N19_RS02015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N19_RS02020	COG1335	isochorismatase
C6N19_RS02025	COG1522	sequence-specific DNA binding
C6N19_RS02050	COG2205	protein histidine kinase activity
C6N19_RS02050	COG2198	Histidine kinase
C6N19_RS02050	COG0784	Response regulator, receiver
C6N19_RS02055	COG3162	membrane
C6N19_RS02060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N19_RS02070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N19_RS02090	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS02105	COG1309	transcriptional regulator
C6N19_RS02125	COG0300	oxidoreductase activity
C6N19_RS02130	COG0789	Transcriptional regulator
C6N19_RS02135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6N19_RS02135	COG0351	phosphomethylpyrimidine kinase
C6N19_RS02135	COG0352	thiamine-phosphate diphosphorylase activity
C6N19_RS02145	COG2814	Major facilitator Superfamily
C6N19_RS02160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6N19_RS02170	COG1113	amino acid transport
C6N19_RS02180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N19_RS02185	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS02195	COG1335	isochorismatase
C6N19_RS02235	COG2814	Major facilitator Superfamily
C6N19_RS02240	COG0583	DNA-binding transcription factor activity
C6N19_RS02260	COG0667	Aldo Keto reductase
C6N19_RS02280	COG1309	transcriptional regulator
C6N19_RS02295	COG3328	transposase activity
C6N19_RS02305	COG1733	regulation of RNA biosynthetic process
C6N19_RS02310	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N19_RS02330	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS02405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N19_RS02420	COG2329	Antibiotic biosynthesis monooxygenase
C6N19_RS02425	COG0697	spore germination
C6N19_RS02435	COG1132	(ABC) transporter
C6N19_RS02445	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6N19_RS02455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6N19_RS02485	COG0427	acetyl-CoA hydrolase
C6N19_RS02510	COG0659	secondary active sulfate transmembrane transporter activity
C6N19_RS02515	COG4221	oxidoreductase activity
C6N19_RS02520	COG2873	o-acetylhomoserine
C6N19_RS02525	COG0488	(ABC) transporter
C6N19_RS02610	COG0833	amino acid
C6N19_RS02655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6N19_RS02660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6N19_RS02675	COG2226	methyltransferase
C6N19_RS02725	COG0067	glutamate synthase
C6N19_RS02725	COG0069	glutamate synthase activity
C6N19_RS02725	COG0070	glutamate synthase
C6N19_RS02730	COG0493	'glutamate synthase
C6N19_RS02740	COG1704	LemA family
C6N19_RS02745	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6N19_RS02755	COG4969	Belongs to the N-Me-Phe pilin family
C6N19_RS02765	COG3328	transposase activity
C6N19_RS02775	COG3307	-O-antigen
C6N19_RS02800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N19_RS02815	COG0194	GDP metabolic process
C6N19_RS02865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C6N19_RS02875	COG0335	large ribosomal subunit rRNA binding
C6N19_RS02885	COG5380	lipid catabolic process
C6N19_RS02890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C6N19_RS02905	COG5006	permease, DMT superfamily
C6N19_RS02910	COG5006	permease, DMT superfamily
C6N19_RS02915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6N19_RS02920	COG0277	FAD linked oxidase domain protein
C6N19_RS02930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6N19_RS02935	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N19_RS02950	COG1289	transmembrane transporter activity
C6N19_RS02960	COG0628	permease
C6N19_RS02965	COG1192	Involved in chromosome partitioning
C6N19_RS02995	COG0833	amino acid
C6N19_RS03000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6N19_RS03005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N19_RS03015	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS03055	COG0583	DNA-binding transcription factor activity
C6N19_RS03085	COG0752	glycyl-tRNA synthetase alpha subunit
C6N19_RS03105	COG0517	IMP dehydrogenase activity
C6N19_RS03110	COG1983	PspC domain protein
C6N19_RS03120	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS03130	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS03145	COG0408	coproporphyrinogen oxidase activity
C6N19_RS03165	COG0513	Belongs to the DEAD box helicase family
C6N19_RS03175	COG1127	ABC transporter
C6N19_RS03180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6N19_RS03190	COG2854	intermembrane phospholipid transfer
C6N19_RS03200	COG0598	Magnesium transport protein CorA
C6N19_RS03210	COG0494	nUDIX hydrolase
C6N19_RS03215	COG1040	competence protein
C6N19_RS03220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6N19_RS03240	COG1946	Acyl-CoA thioesterase
C6N19_RS03245	COG1301	dicarboxylic acid transport
C6N19_RS03260	COG1959	2 iron, 2 sulfur cluster binding
C6N19_RS03265	COG1017	nitric oxide dioxygenase activity
C6N19_RS03265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N19_RS03275	COG0433	COG0433 Predicted ATPase
C6N19_RS03280	COG0626	cystathionine gamma-synthase activity
C6N19_RS03295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C6N19_RS03300	COG0088	Forms part of the polypeptide exit tunnel
C6N19_RS03435	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS03440	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6N19_RS03470	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6N19_RS03475	COG0339	signal peptide processing
C6N19_RS03480	COG0557	exoribonuclease II activity
C6N19_RS03530	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6N19_RS03535	COG1295	ribonuclease BN
C6N19_RS03570	COG1702	phosphate starvation-inducible protein PhoH
C6N19_RS03580	COG1196	nuclear chromosome segregation
C6N19_RS03580	COG0739	heme binding
C6N19_RS03580	COG0741	lytic transglycosylase activity
C6N19_RS03610	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6N19_RS03615	COG1183	phosphatidylcholine synthase activity
C6N19_RS03660	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS03665	COG1309	transcriptional regulator
C6N19_RS03680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6N19_RS03685	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS03710	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS03730	COG2969	positive regulation of protein catabolic process
C6N19_RS03740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C6N19_RS03745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C6N19_RS03750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C6N19_RS03755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C6N19_RS03760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6N19_RS03780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6N19_RS03790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N19_RS03795	COG1408	metallophosphoesterase
C6N19_RS03800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6N19_RS03800	COG2885	chlorophyll binding
C6N19_RS03805	COG2199	diguanylate cyclase activity
C6N19_RS03875	COG1607	acyl-coa hydrolase
C6N19_RS03910	COG2350	Protein conserved in bacteria
C6N19_RS03925	COG3781	membrane
C6N19_RS03935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6N19_RS03940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6N19_RS03950	COG1862	Preprotein translocase
C6N19_RS03985	COG0784	Response regulator, receiver
C6N19_RS03985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N19_RS03985	COG2198	Histidine kinase
C6N19_RS03985	COG2205	protein histidine kinase activity
C6N19_RS03990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C6N19_RS04005	COG0726	polysaccharide deacetylase
C6N19_RS04080	COG0625	glutathione transferase activity
C6N19_RS04085	COG0583	DNA-binding transcription factor activity
C6N19_RS04090	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS04095	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS04105	COG2205	protein histidine kinase activity
C6N19_RS04110	COG0745	RESPONSE REGULATOR receiver
C6N19_RS04120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C6N19_RS04140	COG2096	Adenosyltransferase
C6N19_RS04145	COG4206	TonB-dependent receptor
C6N19_RS04190	COG0285	dihydrofolate synthase activity
C6N19_RS04210	COG0450	alkyl hydroperoxide reductase
C6N19_RS04225	COG0477	Major facilitator Superfamily
C6N19_RS04230	COG1272	protein, Hemolysin III
C6N19_RS04240	COG2153	protein acetylation
C6N19_RS04260	COG0183	Belongs to the thiolase family
C6N19_RS04265	COG2207	Transcriptional regulator
C6N19_RS04285	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N19_RS04305	COG0183	Belongs to the thiolase family
C6N19_RS04315	COG2885	chlorophyll binding
C6N19_RS04315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6N19_RS04320	COG1690	Belongs to the RtcB family
C6N19_RS04325	COG0833	amino acid
C6N19_RS04335	COG2233	PERMEase
C6N19_RS04340	COG1217	gtp-binding protein TYPA
C6N19_RS04365	COG2094	Belongs to the DNA glycosylase MPG family
C6N19_RS04370	COG4772	TonB-dependent receptor
C6N19_RS04375	COG1902	pentaerythritol trinitrate reductase activity
C6N19_RS04390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N19_RS04395	COG0354	folic acid binding
C6N19_RS04415	COG2233	PERMEase
C6N19_RS04420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N19_RS04425	COG0251	oxidation-reduction process
C6N19_RS04430	COG1335	isochorismatase
C6N19_RS04435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N19_RS04440	COG0778	Nitroreductase
C6N19_RS04445	COG0596	Alpha beta hydrolase
C6N19_RS04450	COG3189	MarR family transcriptional regulator
C6N19_RS04455	COG2824	Alkylphosphonate utilization operon protein PhnA
C6N19_RS04460	COG3422	double-strand break repair
C6N19_RS04500	COG0840	transmembrane signaling receptor activity
C6N19_RS04520	COG5510	response to toxic substance
C6N19_RS04530	COG2832	Protein of unknown function (DUF454)
C6N19_RS04535	COG1376	ErfK ybiS ycfS ynhG family protein
C6N19_RS04575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C6N19_RS04585	COG1289	transmembrane transporter activity
C6N19_RS04590	COG2814	Major facilitator Superfamily
C6N19_RS04615	COG1115	amino acid carrier protein
C6N19_RS04620	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6N19_RS04625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N19_RS04630	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6N19_RS04635	COG3590	peptidase
C6N19_RS04660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6N19_RS04670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6N19_RS04675	COG1077	Cell shape determining protein MreB Mrl
C6N19_RS04680	COG1792	Involved in formation and maintenance of cell shape
C6N19_RS04685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6N19_RS04690	COG0424	maF-like protein
C6N19_RS04695	COG1530	ribonuclease E activity
C6N19_RS04705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N19_RS04725	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N19_RS04750	COG2207	Transcriptional regulator
C6N19_RS04780	COG3046	protein related to deoxyribodipyrimidine photolyase
C6N19_RS04790	COG1113	amino acid transport
C6N19_RS04795	COG2828	Protein conserved in bacteria
C6N19_RS04800	COG0142	geranyltranstransferase activity
C6N19_RS04805	COG2315	Protein conserved in bacteria
C6N19_RS04820	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6N19_RS04845	COG2194	sulfuric ester hydrolase activity
C6N19_RS04850	COG0745	RESPONSE REGULATOR receiver
C6N19_RS04855	COG0642	Histidine kinase
C6N19_RS04870	COG0004	ammonium transporteR
C6N19_RS04900	COG0525	valine-tRNA ligase activity
C6N19_RS04910	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS04920	COG0393	Putative heavy-metal-binding
C6N19_RS04925	COG0393	Putative heavy-metal-binding
C6N19_RS04930	COG1538	Outer membrane efflux protein
C6N19_RS04940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS04945	COG0671	phosphoesterase, PA-phosphatase related
C6N19_RS04970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C6N19_RS04985	COG1648	precorrin-2 dehydrogenase activity
C6N19_RS04985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C6N19_RS04990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6N19_RS05025	COG0531	amino acid
C6N19_RS05040	COG0321	lipoyl(octanoyl) transferase activity
C6N19_RS05045	COG2921	Belongs to the UPF0250 family
C6N19_RS05085	COG2009	succinate dehydrogenase
C6N19_RS05090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6N19_RS05095	COG1053	succinate dehydrogenase
C6N19_RS05100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6N19_RS05125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N19_RS05145	COG2354	Protein conserved in bacteria
C6N19_RS05150	COG2321	neutral zinc metallopeptidase
C6N19_RS05260	COG2843	Capsule synthesis protein
C6N19_RS05280	COG0589	response to stress
C6N19_RS05290	COG0251	oxidation-reduction process
C6N19_RS05295	COG1309	transcriptional regulator
C6N19_RS05310	COG0505	Belongs to the CarA family
C6N19_RS05345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6N19_RS05350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6N19_RS05395	COG2264	protein methyltransferase activity
C6N19_RS05405	COG0477	Major facilitator Superfamily
C6N19_RS05410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6N19_RS05425	COG1597	lipid kinase activity
C6N19_RS05430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6N19_RS05470	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS05495	COG2801	Transposase and inactivated derivatives
C6N19_RS05570	COG2814	Major facilitator Superfamily
C6N19_RS05600	COG1074	ATP-dependent DNA helicase activity
C6N19_RS05605	COG0582	viral genome integration into host DNA
C6N19_RS05615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N19_RS05620	COG0584	glycerophosphoryl diester phosphodiesterase
C6N19_RS05640	COG0741	lytic transglycosylase activity
C6N19_RS05665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6N19_RS05690	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS05700	COG2801	Transposase and inactivated derivatives
C6N19_RS05725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS05730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N19_RS05735	COG0778	Nitroreductase
C6N19_RS05750	COG1929	Belongs to the glycerate kinase type-1 family
C6N19_RS05755	COG0243	molybdopterin cofactor binding
C6N19_RS05760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C6N19_RS05765	COG3339	Conserved Protein
C6N19_RS05790	COG1115	amino acid carrier protein
C6N19_RS05795	COG1113	amino acid transport
C6N19_RS05805	COG0019	diaminopimelate decarboxylase activity
C6N19_RS05815	COG1280	lysine exporter protein (LysE YggA)
C6N19_RS05820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C6N19_RS05850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS05880	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6N19_RS05885	COG1136	(ABC) transporter
C6N19_RS05900	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C6N19_RS05900	COG0616	signal peptide processing
C6N19_RS05905	COG0596	Alpha beta hydrolase
C6N19_RS05910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6N19_RS05920	COG0628	permease
C6N19_RS05960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N19_RS05980	COG0823	Involved in the tonB-independent uptake of proteins
C6N19_RS06000	COG0824	Thioesterase
C6N19_RS06005	COG1473	amidohydrolase
C6N19_RS06025	COG0047	phosphoribosylformylglycinamidine synthase activity
C6N19_RS06025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6N19_RS06030	COG2814	Major facilitator Superfamily
C6N19_RS06035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N19_RS06040	COG1024	Enoyl-CoA hydratase
C6N19_RS06045	COG1056	cytidyltransferase-related domain
C6N19_RS06045	COG1051	belongs to the nudix hydrolase family
C6N19_RS06060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6N19_RS06075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C6N19_RS06090	COG4625	pathogenesis
C6N19_RS06095	COG0583	DNA-binding transcription factor activity
C6N19_RS06100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6N19_RS06105	COG4208	sulfate ABC transporter
C6N19_RS06110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6N19_RS06120	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6N19_RS06125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N19_RS06130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6N19_RS06150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N19_RS06160	COG0481	GTPase activity
C6N19_RS06165	COG0681	Belongs to the peptidase S26 family
C6N19_RS06175	COG0571	ribonuclease III activity
C6N19_RS06180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C6N19_RS06195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6N19_RS06205	COG4221	oxidoreductase activity
C6N19_RS06235	COG0436	Aminotransferase
C6N19_RS06255	COG0556	nucleotide-excision repair
C6N19_RS06265	COG2962	Rard protein
C6N19_RS06310	COG2070	2-Nitropropane dioxygenase
C6N19_RS06325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N19_RS06340	COG1215	transferase activity, transferring glycosyl groups
C6N19_RS06355	COG0415	Belongs to the DNA photolyase family
C6N19_RS06365	COG1252	NADH dehydrogenase
C6N19_RS06370	COG1686	Belongs to the peptidase S11 family
C6N19_RS06385	COG1187	pseudouridine synthase activity
C6N19_RS06400	COG0477	Major facilitator Superfamily
C6N19_RS06405	COG0583	DNA-binding transcription factor activity
C6N19_RS06410	COG1823	symporter activity
C6N19_RS06420	COG0612	Peptidase, M16
C6N19_RS06445	COG0352	thiamine-phosphate diphosphorylase activity
C6N19_RS06480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N19_RS06495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N19_RS06500	COG0076	glutamate decarboxylase activity
C6N19_RS06510	COG1522	sequence-specific DNA binding
C6N19_RS06515	COG3961	Belongs to the TPP enzyme family
C6N19_RS06520	COG1113	amino acid transport
C6N19_RS06525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N19_RS06530	COG0573	inorganic phosphate transmembrane transporter activity
C6N19_RS06540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6N19_RS06545	COG0616	signal peptide processing
C6N19_RS06555	COG3328	transposase activity
C6N19_RS06590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6N19_RS06595	COG1686	Belongs to the peptidase S11 family
C6N19_RS06640	COG0582	viral genome integration into host DNA
C6N19_RS06655	COG0583	DNA-binding transcription factor activity
C6N19_RS06660	COG1067	ATP-dependent peptidase activity
C6N19_RS06700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C6N19_RS06705	COG1966	Carbon starvation protein
C6N19_RS06710	COG2879	small protein
C6N19_RS06740	COG2801	Transposase and inactivated derivatives
C6N19_RS06760	COG1741	Belongs to the pirin family
C6N19_RS06775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N19_RS06780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N19_RS06785	COG4605	iron ion homeostasis
C6N19_RS06790	COG4604	ABC transporter, ATP-binding protein
C6N19_RS06795	COG4607	ABC-type enterochelin transport system periplasmic component
C6N19_RS06800	COG4774	siderophore transport
C6N19_RS06810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N19_RS06815	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6N19_RS06820	COG1535	isochorismatase
C6N19_RS06820	COG3433	isochorismatase activity
C6N19_RS06835	COG1132	(ABC) transporter
C6N19_RS06840	COG1132	(ABC) transporter
C6N19_RS06845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C6N19_RS06850	COG2977	Belongs to the P-Pant transferase superfamily
C6N19_RS06855	COG1169	isochorismate synthase
C6N19_RS06875	COG3739	integral membrane protein
C6N19_RS06895	COG0302	gtp cyclohydrolase
C6N19_RS06905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6N19_RS06915	COG2840	Smr protein MutS2
C6N19_RS06950	COG0512	Glutamine amidotransferase of anthranilate synthase
C6N19_RS06965	COG0174	glutamine synthetase
C6N19_RS06975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C6N19_RS07010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N19_RS07015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N19_RS07020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N19_RS07040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N19_RS07045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6N19_RS07050	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C6N19_RS07065	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS07070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C6N19_RS07075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N19_RS07085	COG2223	nitrite transmembrane transporter activity
C6N19_RS07095	COG0024	Methionine aminopeptidase
C6N19_RS07100	COG0052	Belongs to the universal ribosomal protein uS2 family
C6N19_RS07140	COG2951	lytic endotransglycosylase activity
C6N19_RS07145	COG0772	Belongs to the SEDS family
C6N19_RS07160	COG0842	Transport permease protein
C6N19_RS07165	COG1131	(ABC) transporter
C6N19_RS07210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS07220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N19_RS07225	COG4215	(ABC) transporter
C6N19_RS07230	COG4160	amino acid transport
C6N19_RS07235	COG4598	ABC transporter
C6N19_RS07245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N19_RS07250	COG0826	peptidase U32
C6N19_RS07255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS07260	COG0384	phenazine biosynthesis protein PhzF
C6N19_RS07270	COG1720	tRNA m6t6A37 methyltransferase activity
C6N19_RS07280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6N19_RS07295	COG0642	Histidine kinase
C6N19_RS07305	COG0494	nUDIX hydrolase
C6N19_RS07315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N19_RS07320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C6N19_RS07325	COG3139	Protein of unknown function (DUF1315)
C6N19_RS07330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6N19_RS07340	COG1301	dicarboxylic acid transport
C6N19_RS07345	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS07360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6N19_RS07370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6N19_RS07375	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6N19_RS07395	COG1690	Belongs to the RtcB family
C6N19_RS07400	COG1234	tRNA 3'-trailer cleavage
C6N19_RS07405	COG4650	regulator
C6N19_RS07435	COG2363	Small membrane protein
C6N19_RS07455	COG0513	Belongs to the DEAD box helicase family
C6N19_RS07465	COG0778	Nitroreductase
C6N19_RS07495	COG1286	toxin biosynthetic process
C6N19_RS07520	COG4783	chaperone-mediated protein folding
C6N19_RS07525	COG1610	YqeY-like protein
C6N19_RS07580	COG1278	Cold shock
C6N19_RS07595	COG3243	poly(R)-hydroxyalkanoic acid synthase
C6N19_RS07600	COG0786	glutamate:sodium symporter activity
C6N19_RS07605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N19_RS07605	COG0475	glutathione-regulated potassium exporter activity
C6N19_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS07645	COG1309	transcriptional regulator
C6N19_RS07655	COG2985	domain, Protein
C6N19_RS07670	COG2995	paraquat-inducible protein a
C6N19_RS07675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6N19_RS07675	COG3008	intermembrane lipid transfer
C6N19_RS07685	COG2351	hydroxyisourate hydrolase activity
C6N19_RS07735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6N19_RS07745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6N19_RS07750	COG0642	Histidine kinase
C6N19_RS07755	COG0745	RESPONSE REGULATOR receiver
C6N19_RS07770	COG1794	racemase activity, acting on amino acids and derivatives
C6N19_RS07800	COG1301	dicarboxylic acid transport
C6N19_RS07805	COG3328	transposase activity
C6N19_RS07815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N19_RS07820	COG2011	ABC-type metal ion transport system permease component
C6N19_RS07825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N19_RS07835	COG0151	Belongs to the GarS family
C6N19_RS07845	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C6N19_RS07875	COG2308	Evidence 4 Homologs of previously reported genes of
C6N19_RS07885	COG1305	Transglutaminase-like
C6N19_RS07895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6N19_RS07900	COG0305	Participates in initiation and elongation during chromosome replication
C6N19_RS07925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6N19_RS07930	COG1845	cytochrome c oxidase, subunit III
C6N19_RS07935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6N19_RS07965	COG0726	polysaccharide deacetylase
C6N19_RS07965	COG1649	PFAM Uncharacterised BCR, COG1649
C6N19_RS07970	COG1215	transferase activity, transferring glycosyl groups
C6N19_RS07975	COG3658	cytochrome
C6N19_RS07985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N19_RS08000	COG0583	DNA-binding transcription factor activity
C6N19_RS08015	COG2890	protein-(glutamine-N5) methyltransferase activity
C6N19_RS08020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N19_RS08025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N19_RS08040	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS08045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N19_RS08060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6N19_RS08070	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C6N19_RS08075	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C6N19_RS08085	COG2205	protein histidine kinase activity
C6N19_RS08090	COG0745	RESPONSE REGULATOR receiver
C6N19_RS08095	COG0174	glutamine synthetase
C6N19_RS08115	COG0729	surface antigen
C6N19_RS08150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N19_RS08155	COG2814	Major facilitator Superfamily
C6N19_RS08165	COG0583	DNA-binding transcription factor activity
C6N19_RS08180	COG1187	pseudouridine synthase activity
C6N19_RS08200	COG0802	atpase or kinase
C6N19_RS08205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C6N19_RS08215	COG1923	regulation of RNA biosynthetic process
C6N19_RS08220	COG0697	spore germination
C6N19_RS08245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6N19_RS08250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6N19_RS08250	COG0519	Catalyzes the synthesis of GMP from XMP
C6N19_RS08255	COG4302	ethanolamine ammonia-lyase activity
C6N19_RS08260	COG4303	Ethanolamine ammonia lyase large subunit
C6N19_RS08265	COG0531	amino acid
C6N19_RS08285	COG1454	alcohol dehydrogenase
C6N19_RS08290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N19_RS08315	COG0308	aminopeptidase N
C6N19_RS08325	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS08360	COG1605	Chorismate mutase
C6N19_RS08380	COG4772	TonB-dependent receptor
C6N19_RS08385	COG4774	siderophore transport
C6N19_RS08435	COG3772	lysozyme
C6N19_RS08445	COG1733	regulation of RNA biosynthetic process
C6N19_RS08450	COG3328	transposase activity
C6N19_RS08475	COG0583	DNA-binding transcription factor activity
C6N19_RS08510	COG0488	(ABC) transporter
C6N19_RS08515	COG0589	response to stress
C6N19_RS08535	COG3135	benzoate transporter
C6N19_RS08540	COG1522	sequence-specific DNA binding
C6N19_RS08550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N19_RS08555	COG0583	DNA-binding transcription factor activity
C6N19_RS08565	COG0183	Belongs to the thiolase family
C6N19_RS08570	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS08575	COG2030	dehydratase
C6N19_RS08580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N19_RS08605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6N19_RS08615	COG0824	Thioesterase
C6N19_RS08620	COG1454	alcohol dehydrogenase
C6N19_RS08640	COG1335	isochorismatase
C6N19_RS08660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6N19_RS08690	COG0069	glutamate synthase activity
C6N19_RS08725	COG2814	Major facilitator Superfamily
C6N19_RS08740	COG0511	ligase activity, forming carbon-carbon bonds
C6N19_RS08765	COG4264	IucA IucC family
C6N19_RS08775	COG4264	IucA IucC family
C6N19_RS08780	COG2423	ornithine cyclodeaminase activity
C6N19_RS08785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N19_RS08790	COG1116	anion transmembrane transporter activity
C6N19_RS08790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N19_RS08805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N19_RS08805	COG2146	nitrite reductase [NAD(P)H] activity
C6N19_RS08810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N19_RS08815	COG0243	molybdopterin cofactor binding
C6N19_RS08825	COG0243	molybdopterin cofactor binding
C6N19_RS08830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C6N19_RS08845	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6N19_RS08845	COG0315	cyclic pyranopterin monophosphate synthase activity
C6N19_RS08850	COG0303	'Molybdopterin
C6N19_RS08860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS08865	COG0697	spore germination
C6N19_RS08890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6N19_RS08965	COG2204	response regulator
C6N19_RS08970	COG3852	Histidine kinase
C6N19_RS08995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6N19_RS09000	COG0575	Belongs to the CDS family
C6N19_RS09035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6N19_RS09050	COG2137	regulation of response to DNA damage stimulus
C6N19_RS09060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6N19_RS09065	COG1011	Hydrolase
C6N19_RS09080	COG1522	sequence-specific DNA binding
C6N19_RS09090	COG1113	amino acid transport
C6N19_RS09095	COG0657	acetylesterase activity
C6N19_RS09110	COG0659	secondary active sulfate transmembrane transporter activity
C6N19_RS09150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N19_RS09150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N19_RS09150	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6N19_RS09155	COG1105	Belongs to the carbohydrate kinase PfkB family
C6N19_RS09160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N19_RS09160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N19_RS09180	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6N19_RS09190	COG0024	Methionine aminopeptidase
C6N19_RS09195	COG0583	DNA-binding transcription factor activity
C6N19_RS09205	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6N19_RS09210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N19_RS09215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6N19_RS09215	COG0517	IMP dehydrogenase activity
C6N19_RS09240	COG0552	protein localization to endoplasmic reticulum
C6N19_RS09265	COG4890	Cyd operon protein YbgT
C6N19_RS09270	COG1294	oxidase, subunit
C6N19_RS09285	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6N19_RS09295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N19_RS09310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N19_RS09315	COG0569	domain protein
C6N19_RS09320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N19_RS09350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C6N19_RS09355	COG0542	response to heat
C6N19_RS09365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6N19_RS09380	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N19_RS09380	COG1902	pentaerythritol trinitrate reductase activity
C6N19_RS09420	COG0148	phosphopyruvate hydratase activity
C6N19_RS09425	COG2323	membrane
C6N19_RS09435	COG4773	Receptor
C6N19_RS09440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C6N19_RS09450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N19_RS09455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N19_RS09460	COG0183	Belongs to the thiolase family
C6N19_RS09465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6N19_RS09470	COG0596	Alpha beta hydrolase
C6N19_RS09475	COG2271	Major facilitator Superfamily
C6N19_RS09480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N19_RS09485	COG3485	protocatechuate 3,4-dioxygenase
C6N19_RS09490	COG3485	protocatechuate 3,4-dioxygenase
C6N19_RS09495	COG0710	3-dehydroquinate dehydratase activity
C6N19_RS09500	COG3420	alginic acid biosynthetic process
C6N19_RS09505	COG3659	wide pore channel activity
C6N19_RS09510	COG4993	Dehydrogenase
C6N19_RS09520	COG2391	methyltransferase activity
C6N19_RS09535	COG1414	Transcriptional regulator
C6N19_RS09540	COG0583	DNA-binding transcription factor activity
C6N19_RS09545	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS09570	COG2814	Major facilitator Superfamily
C6N19_RS09580	COG0154	amidase activity
C6N19_RS09600	COG4638	Rieske (2fe-2S)
C6N19_RS09610	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS09620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N19_RS09630	COG3733	amine oxidase
C6N19_RS09650	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS09655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N19_RS09660	COG0183	Belongs to the thiolase family
C6N19_RS09665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N19_RS09670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N19_RS09680	COG4829	muconolactone delta-isomerase
C6N19_RS09685	COG4948	Mandelate Racemase Muconate Lactonizing
C6N19_RS09690	COG0583	DNA-binding transcription factor activity
C6N19_RS09700	COG2186	Transcriptional regulator
C6N19_RS09720	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS09725	COG2351	hydroxyisourate hydrolase activity
C6N19_RS09730	COG2233	PERMEase
C6N19_RS09740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N19_RS09745	COG2186	Transcriptional regulator
C6N19_RS09760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N19_RS09770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N19_RS09790	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N19_RS09790	COG1902	pentaerythritol trinitrate reductase activity
C6N19_RS09830	COG1309	transcriptional regulator
C6N19_RS09835	COG0583	DNA-binding transcription factor activity
C6N19_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS09845	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS09860	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS09870	COG0318	PFAM AMP-dependent synthetase and ligase
C6N19_RS09885	COG1309	transcriptional regulator
C6N19_RS09945	COG0583	DNA-binding transcription factor activity
C6N19_RS10020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N19_RS10025	COG1120	ATPase activity
C6N19_RS10035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N19_RS10055	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS10090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C6N19_RS10140	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C6N19_RS10150	COG4628	conserved protein (DUF2132)
C6N19_RS10165	COG3539	Fimbrial protein
C6N19_RS10190	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C6N19_RS10205	COG0753	catalase activity
C6N19_RS10225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N19_RS10235	COG2205	protein histidine kinase activity
C6N19_RS10240	COG0745	RESPONSE REGULATOR receiver
C6N19_RS10245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS10250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N19_RS10315	COG1535	isochorismatase
C6N19_RS10315	COG3433	isochorismatase activity
C6N19_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS10325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C6N19_RS10330	COG4149	molybdate abc transporter
C6N19_RS10335	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6N19_RS10345	COG4638	Rieske (2fe-2S)
C6N19_RS10350	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6N19_RS10355	COG0543	2 iron, 2 sulfur cluster binding
C6N19_RS10355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N19_RS10380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N19_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS10410	COG2207	Transcriptional regulator
C6N19_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS10420	COG2610	gluconate transmembrane transporter activity
C6N19_RS10425	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS10465	COG0583	DNA-binding transcription factor activity
C6N19_RS10480	COG2031	fatty acid transporter
C6N19_RS10485	COG0183	Belongs to the thiolase family
C6N19_RS10490	COG0583	DNA-binding transcription factor activity
C6N19_RS10495	COG0583	DNA-binding transcription factor activity
C6N19_RS10510	COG1027	Aspartate ammonia-lyase
C6N19_RS10520	COG0477	Major facilitator Superfamily
C6N19_RS10530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N19_RS10535	COG1733	regulation of RNA biosynthetic process
C6N19_RS10540	COG2207	Transcriptional regulator
C6N19_RS10540	COG3708	Transcriptional regulator
C6N19_RS10555	COG0730	response to heat
C6N19_RS10575	COG3781	membrane
C6N19_RS10580	COG1063	alcohol dehydrogenase
C6N19_RS10590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N19_RS10595	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N19_RS10600	COG0022	dehydrogenase e1 component
C6N19_RS10605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6N19_RS10610	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS10615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C6N19_RS10630	COG3706	GGDEF domain
C6N19_RS10650	COG0133	tryptophan synthase activity
C6N19_RS10660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6N19_RS10690	COG0583	DNA-binding transcription factor activity
C6N19_RS10695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N19_RS10705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C6N19_RS10765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6N19_RS10770	COG4773	Receptor
C6N19_RS10795	COG0730	response to heat
C6N19_RS10800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6N19_RS10830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C6N19_RS10960	COG2369	cell adhesion
C6N19_RS10965	COG4383	Mu-like prophage protein gp29
C6N19_RS10980	COG4373	Mu-like prophage FluMu protein gp28
C6N19_RS11015	COG0681	Belongs to the peptidase S26 family
C6N19_RS11040	COG3409	Peptidoglycan-binding domain 1 protein
C6N19_RS11040	COG3267	Type II secretory pathway component ExeA
C6N19_RS11120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6N19_RS11135	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS11140	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS11145	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N19_RS11150	COG2207	Transcriptional regulator
C6N19_RS11155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N19_RS11160	COG0776	regulation of translation
C6N19_RS11185	COG0822	iron-sulfur transferase activity
C6N19_RS11190	COG0316	Belongs to the HesB IscA family
C6N19_RS11220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6N19_RS11240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C6N19_RS11245	COG0702	epimerase
C6N19_RS11285	COG0601	transmembrane transport
C6N19_RS11290	COG0339	signal peptide processing
C6N19_RS11295	COG4166	transmembrane transport
C6N19_RS11340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6N19_RS11345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6N19_RS11360	COG2431	L-lysine efflux transmembrane transporter activity
C6N19_RS11375	COG0776	regulation of translation
C6N19_RS11440	COG0084	hydrolase, TatD family'
C6N19_RS11460	COG1663	tetraacyldisaccharide 4'-kinase activity
C6N19_RS11465	COG1132	(ABC) transporter
C6N19_RS11475	COG0811	peptide transport
C6N19_RS11480	COG1475	DNA binding
C6N19_RS11485	COG1192	Involved in chromosome partitioning
C6N19_RS11495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C6N19_RS11500	COG3178	'Phosphotransferase
C6N19_RS11510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N19_RS11535	COG0424	maF-like protein
C6N19_RS11540	COG2850	peptidyl-arginine hydroxylation
C6N19_RS11550	COG0640	Transcriptional regulator
C6N19_RS11560	COG3619	membrane
C6N19_RS11565	COG3122	Protein conserved in bacteria
C6N19_RS11570	COG1132	(ABC) transporter
C6N19_RS11590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6N19_RS11595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N19_RS11605	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N19_RS11605	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N19_RS11605	COG0506	proline dehydrogenase activity
C6N19_RS11610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6N19_RS11625	COG3698	Phosphodiester glycosidase
C6N19_RS11635	COG2353	YceI-like domain
C6N19_RS11645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6N19_RS11690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6N19_RS11690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6N19_RS11715	COG3539	Fimbrial protein
C6N19_RS11750	COG0583	DNA-binding transcription factor activity
C6N19_RS11755	COG0697	spore germination
C6N19_RS11765	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6N19_RS11780	COG0583	DNA-binding transcription factor activity
C6N19_RS11795	COG1309	transcriptional regulator
C6N19_RS11810	COG1522	sequence-specific DNA binding
C6N19_RS11820	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS11830	COG1126	abc transporter atp-binding protein
C6N19_RS11835	COG0765	amino acid transport
C6N19_RS11840	COG0765	amino acid transport
C6N19_RS11870	COG1464	Belongs to the NlpA lipoprotein family
C6N19_RS11880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N19_RS11885	COG2011	ABC-type metal ion transport system permease component
C6N19_RS11890	COG0012	GTP binding
C6N19_RS11915	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6N19_RS11950	COG2207	Transcriptional regulator
C6N19_RS11950	COG1917	Cupin 2, conserved barrel domain protein
C6N19_RS11955	COG0386	Belongs to the glutathione peroxidase family
C6N19_RS11965	COG0436	Aminotransferase
C6N19_RS11970	COG1301	dicarboxylic acid transport
C6N19_RS12005	COG3634	alkyl hydroperoxide reductase activity
C6N19_RS12020	COG0583	DNA-binding transcription factor activity
C6N19_RS12025	COG0431	NADPH-dependent FMN reductase
C6N19_RS12030	COG0798	PFAM Bile acid sodium symporter
C6N19_RS12040	COG0640	Transcriptional regulator
C6N19_RS12055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C6N19_RS12065	COG0583	DNA-binding transcription factor activity
C6N19_RS12075	COG1953	Uracil, thiamine, allantoin
C6N19_RS12085	COG2175	clavaminate synthase activity
C6N19_RS12090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N19_RS12095	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C6N19_RS12100	COG4521	taurine ABC transporter
C6N19_RS12110	COG0477	Major facilitator Superfamily
C6N19_RS12130	COG1271	oxidase subunit
C6N19_RS12135	COG1294	oxidase, subunit
C6N19_RS12145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS12165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6N19_RS12185	COG3052	prosthetic group binding
C6N19_RS12190	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C6N19_RS12215	COG1346	cytolysis
C6N19_RS12225	COG0583	DNA-binding transcription factor activity
C6N19_RS12230	COG0625	glutathione transferase activity
C6N19_RS12235	COG0625	glutathione transferase activity
C6N19_RS12255	COG0583	DNA-binding transcription factor activity
C6N19_RS12270	COG1045	serine acetyltransferase
C6N19_RS12275	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS12280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N19_RS12285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6N19_RS12290	COG1280	lysine exporter protein (LysE YggA)
C6N19_RS12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N19_RS12310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N19_RS12320	COG0765	amino acid transport
C6N19_RS12325	COG0765	amino acid transport
C6N19_RS12345	COG0784	Response regulator, receiver
C6N19_RS12345	COG2205	protein histidine kinase activity
C6N19_RS12365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6N19_RS12380	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS12390	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS12435	COG0583	DNA-binding transcription factor activity
C6N19_RS12450	COG2814	Major facilitator Superfamily
C6N19_RS12465	COG0318	PFAM AMP-dependent synthetase and ligase
C6N19_RS12470	COG1309	transcriptional regulator
C6N19_RS12475	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS12480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6N19_RS12485	COG1024	Enoyl-CoA hydratase
C6N19_RS12490	COG4770	biotin carboxylase activity
C6N19_RS12500	COG0583	DNA-binding transcription factor activity
C6N19_RS12515	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS12525	COG2814	Major facilitator Superfamily
C6N19_RS12535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N19_RS12540	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N19_RS12545	COG2814	Major facilitator Superfamily
C6N19_RS12550	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS12555	COG1024	Enoyl-CoA hydratase
C6N19_RS12560	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS12565	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N19_RS12570	COG0183	Belongs to the thiolase family
C6N19_RS12580	COG2814	Major facilitator Superfamily
C6N19_RS12590	COG1024	Enoyl-CoA hydratase
C6N19_RS12605	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS12610	COG2814	Major facilitator Superfamily
C6N19_RS12615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N19_RS12620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C6N19_RS12635	COG3842	ATPase activity
C6N19_RS12640	COG1840	ABC-type Fe3 transport system, periplasmic component
C6N19_RS12655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N19_RS12660	COG1414	Transcriptional regulator
C6N19_RS12670	COG0583	DNA-binding transcription factor activity
C6N19_RS12685	COG2801	Transposase and inactivated derivatives
C6N19_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS12735	COG0583	DNA-binding transcription factor activity
C6N19_RS12740	COG2050	protein possibly involved in aromatic compounds catabolism
C6N19_RS12750	COG3327	negative regulation of DNA-templated transcription, initiation
C6N19_RS12755	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6N19_RS12760	COG0183	Belongs to the thiolase family
C6N19_RS12765	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N19_RS12770	COG1024	Enoyl-CoA hydratase
C6N19_RS12775	COG1024	Enoyl-CoA hydratase
C6N19_RS12780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N19_RS12785	COG2151	metal-sulfur cluster biosynthetic enzyme
C6N19_RS12790	COG3396	Phenylacetate-CoA oxygenase
C6N19_RS12795	COG3460	Phenylacetate-CoA oxygenase
C6N19_RS12800	COG3396	Phenylacetate-CoA oxygenase
C6N19_RS12805	COG2030	dehydratase
C6N19_RS12805	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS12810	COG1760	l-serine dehydratase
C6N19_RS12830	COG0789	Transcriptional regulator
C6N19_RS12840	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6N19_RS12845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS12860	COG2807	transmembrane transport
C6N19_RS12865	COG0590	tRNA wobble adenosine to inosine editing
C6N19_RS12870	COG0666	response to abiotic stimulus
C6N19_RS12895	COG4770	biotin carboxylase activity
C6N19_RS12910	COG1063	alcohol dehydrogenase
C6N19_RS12915	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N19_RS12940	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS12955	COG3210	domain, Protein
C6N19_RS12960	COG2831	hemolysin activation secretion protein
C6N19_RS12965	COG0038	chloride channel
C6N19_RS12970	COG4770	biotin carboxylase activity
C6N19_RS12990	COG1914	H( )-stimulated, divalent metal cation uptake system
C6N19_RS12995	COG0583	DNA-binding transcription factor activity
C6N19_RS13005	COG1595	DNA-templated transcription, initiation
C6N19_RS13015	COG3220	belongs to the UPF0276 family
C6N19_RS13085	COG0702	epimerase
C6N19_RS13090	COG1733	regulation of RNA biosynthetic process
C6N19_RS13105	COG2801	Transposase and inactivated derivatives
C6N19_RS13120	COG1522	sequence-specific DNA binding
C6N19_RS13125	COG0531	amino acid
C6N19_RS13130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N19_RS13145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N19_RS13160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6N19_RS13170	COG4122	O-methyltransferase activity
C6N19_RS13200	COG1538	Outer membrane efflux protein
C6N19_RS13205	COG1137	ATPase activity
C6N19_RS13210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6N19_RS13220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6N19_RS13270	COG2814	Major facilitator Superfamily
C6N19_RS13280	COG0668	transmembrane transport
C6N19_RS13335	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS13345	COG2226	methyltransferase
C6N19_RS13370	COG1278	Cold shock
C6N19_RS13375	COG1560	Kdo2-lipid A biosynthetic process
C6N19_RS13380	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS13385	COG1280	lysine exporter protein (LysE YggA)
C6N19_RS13420	COG1570	exodeoxyribonuclease VII activity
C6N19_RS13505	COG2871	sodium ion transport
C6N19_RS13515	COG0583	DNA-binding transcription factor activity
C6N19_RS13525	COG4638	Rieske (2fe-2S)
C6N19_RS13530	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6N19_RS13535	COG0633	Ferredoxin
C6N19_RS13535	COG0543	2 iron, 2 sulfur cluster binding
C6N19_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS13545	COG3135	benzoate transporter
C6N19_RS13550	COG2814	Major facilitator Superfamily
C6N19_RS13565	COG1643	Atp-dependent helicase
C6N19_RS13590	COG3634	alkyl hydroperoxide reductase activity
C6N19_RS13610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C6N19_RS13635	COG0625	glutathione transferase activity
C6N19_RS13645	COG2885	chlorophyll binding
C6N19_RS13680	COG0542	response to heat
C6N19_RS13695	COG1765	OsmC-like protein
C6N19_RS13710	COG0667	Aldo Keto reductase
C6N19_RS13725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C6N19_RS13735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6N19_RS13745	COG0582	viral genome integration into host DNA
C6N19_RS13750	COG2194	sulfuric ester hydrolase activity
C6N19_RS13760	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS13785	COG1598	PFAM Uncharacterised protein family UPF0150
C6N19_RS13990	COG0527	aspartate kinase activity
C6N19_RS14000	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C6N19_RS14015	COG3038	cytochrome b561
C6N19_RS14020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C6N19_RS14025	COG2252	PERMEase
C6N19_RS14035	COG1741	Belongs to the pirin family
C6N19_RS14040	COG1309	transcriptional regulator
C6N19_RS14055	COG2072	flavoprotein involved in K transport
C6N19_RS14060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C6N19_RS14065	COG0583	DNA-binding transcription factor activity
C6N19_RS14080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N19_RS14110	COG1944	ATP diphosphatase activity
C6N19_RS14130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6N19_RS14145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N19_RS14165	COG2814	Major facilitator Superfamily
C6N19_RS14170	COG1024	Enoyl-CoA hydratase
C6N19_RS14175	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS14185	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS14210	COG2186	Transcriptional regulator
C6N19_RS14215	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS14225	COG4948	Mandelate Racemase Muconate Lactonizing
C6N19_RS14230	COG2271	Major facilitator Superfamily
C6N19_RS14235	COG2721	sulfolactate sulfo-lyase activity
C6N19_RS14240	COG0697	spore germination
C6N19_RS14255	COG1113	amino acid transport
C6N19_RS14275	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS14295	COG0531	amino acid
C6N19_RS14305	COG1113	amino acid transport
C6N19_RS14345	COG4269	membrane
C6N19_RS14365	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N19_RS14365	COG1902	pentaerythritol trinitrate reductase activity
C6N19_RS14375	COG4251	negative regulation of phosphorylation
C6N19_RS14375	COG3706	GGDEF domain
C6N19_RS14375	COG5001	Diguanylate cyclase
C6N19_RS14375	COG2203	Gaf domain
C6N19_RS14385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N19_RS14410	COG3328	transposase activity
C6N19_RS14420	COG4172	Belongs to the ABC transporter superfamily
C6N19_RS14425	COG4239	(ABC) transporter, permease
C6N19_RS14430	COG4174	ABC transporter (Permease)
C6N19_RS14435	COG4166	transmembrane transport
C6N19_RS14440	COG0741	lytic transglycosylase activity
C6N19_RS14440	COG1388	LysM domain
C6N19_RS14440	COG0741	lytic transglycosylase activity
C6N19_RS14440	COG1388	LysM domain
C6N19_RS14475	COG3328	transposase activity
C6N19_RS14495	COG0583	DNA-binding transcription factor activity
C6N19_RS14500	COG1279	arginine transmembrane transporter activity
C6N19_RS14510	COG0789	Transcriptional regulator
C6N19_RS14520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N19_RS14525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N19_RS14530	COG0006	proline dipeptidase activity
C6N19_RS14570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6N19_RS14585	COG3384	dioxygenase
C6N19_RS14595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6N19_RS14600	COG2878	Part of a membrane complex involved in electron transport
C6N19_RS14605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6N19_RS14630	COG0768	penicillin binding
C6N19_RS14635	COG0742	ribosomal rna small subunit methyltransferase
C6N19_RS14650	COG0830	nickel cation binding
C6N19_RS14660	COG0804	urea catabolic process
C6N19_RS14680	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS14695	COG3015	lipoprotein NlpE involved in copper resistance
C6N19_RS14710	COG1253	flavin adenine dinucleotide binding
C6N19_RS14715	COG2851	Citrate transporter
C6N19_RS14765	COG1773	rubredoxin
C6N19_RS14770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N19_RS14775	COG2267	carboxylic ester hydrolase activity
C6N19_RS14780	COG0583	DNA-binding transcription factor activity
C6N19_RS14810	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6N19_RS14815	COG4181	ATPase activity
C6N19_RS14860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6N19_RS14880	COG0306	phosphate transporter
C6N19_RS14910	COG2223	nitrite transmembrane transporter activity
C6N19_RS14915	COG2207	Transcriptional regulator
C6N19_RS14920	COG2066	Belongs to the glutaminase family
C6N19_RS14925	COG0242	peptide deformylase activity
C6N19_RS14930	COG0477	Major facilitator Superfamily
C6N19_RS14940	COG0028	Belongs to the TPP enzyme family
C6N19_RS14955	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS14960	COG2267	carboxylic ester hydrolase activity
C6N19_RS14970	COG2271	Major facilitator Superfamily
C6N19_RS14975	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N19_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS15005	COG1414	Transcriptional regulator
C6N19_RS15020	COG1024	Enoyl-CoA hydratase
C6N19_RS15030	COG1215	transferase activity, transferring glycosyl groups
C6N19_RS15035	COG1649	PFAM Uncharacterised BCR, COG1649
C6N19_RS15035	COG0726	polysaccharide deacetylase
C6N19_RS15045	COG4681	YaeQ
C6N19_RS15055	COG0523	cobalamin synthesis protein
C6N19_RS15065	COG1607	acyl-coa hydrolase
C6N19_RS15075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N19_RS15080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N19_RS15085	COG1309	transcriptional regulator
C6N19_RS15110	COG2040	homocysteine
C6N19_RS15115	COG0531	amino acid
C6N19_RS15165	COG1401	restriction endodeoxyribonuclease activity
C6N19_RS15185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N19_RS15235	COG3328	transposase activity
C6N19_RS15260	COG0592	DNA-directed DNA polymerase activity
C6N19_RS15285	COG3328	transposase activity
C6N19_RS15395	COG1484	DNA-dependent DNA replication
C6N19_RS15485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N19_RS15550	COG0405	Gamma-glutamyltransferase
C6N19_RS15555	COG2814	Major facilitator Superfamily
C6N19_RS15565	COG2050	protein possibly involved in aromatic compounds catabolism
C6N19_RS15580	COG1090	epimerase
C6N19_RS15600	COG0420	3'-5' exonuclease activity
C6N19_RS15625	COG0735	belongs to the Fur family
C6N19_RS15630	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N19_RS15635	COG2914	Belongs to the UPF0125 (RnfH) family
C6N19_RS15655	COG0121	glutamine amidotransferase
C6N19_RS15670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N19_RS15680	COG0210	DNA helicase
C6N19_RS15685	COG2885	chlorophyll binding
C6N19_RS15690	COG0204	Acyl-transferase
C6N19_RS15705	COG2894	cell division
C6N19_RS15720	COG1280	lysine exporter protein (LysE YggA)
C6N19_RS15725	COG1674	ftsk spoiiie
C6N19_RS15730	COG0492	ferredoxin-NADP+ reductase activity
C6N19_RS15735	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C6N19_RS15745	COG0456	acetyltransferase
C6N19_RS15760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C6N19_RS15765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C6N19_RS15775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C6N19_RS15790	COG1981	membrane
C6N19_RS15800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N19_RS15800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C6N19_RS15820	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS15825	COG4638	Rieske (2fe-2S)
C6N19_RS15830	COG0657	acetylesterase activity
C6N19_RS15840	COG0473	3-isopropylmalate dehydrogenase activity
C6N19_RS15845	COG0583	DNA-binding transcription factor activity
C6N19_RS15865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N19_RS15900	COG0358	DNA primase activity
C6N19_RS15915	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C6N19_RS15945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N19_RS15975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6N19_RS15985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6N19_RS15985	COG0352	thiamine-phosphate diphosphorylase activity
C6N19_RS15985	COG0351	phosphomethylpyrimidine kinase
C6N19_RS15990	COG1652	LysM domain
C6N19_RS16015	COG1399	metal-binding, possibly nucleic acid-binding protein
C6N19_RS16020	COG3101	peptidyl-lysine hydroxylation
C6N19_RS16025	COG0009	L-threonylcarbamoyladenylate synthase
C6N19_RS16030	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C6N19_RS16035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C6N19_RS16050	COG4106	trans-aconitate 2-methyltransferase activity
C6N19_RS16065	COG2226	methyltransferase
C6N19_RS16065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N19_RS16065	COG0596	Alpha beta hydrolase
C6N19_RS16075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C6N19_RS16080	COG2223	nitrite transmembrane transporter activity
C6N19_RS16100	COG1196	nuclear chromosome segregation
C6N19_RS16110	COG0730	response to heat
C6N19_RS16125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6N19_RS16135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N19_RS16190	COG0489	protein tyrosine kinase activity
C6N19_RS16200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N19_RS16200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N19_RS16235	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C6N19_RS16240	COG2081	HI0933 family
C6N19_RS16250	COG0668	transmembrane transport
C6N19_RS16270	COG0583	DNA-binding transcription factor activity
C6N19_RS16290	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N19_RS16295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N19_RS16325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6N19_RS16350	COG2199	diguanylate cyclase activity
C6N19_RS16365	COG0745	RESPONSE REGULATOR receiver
C6N19_RS16380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N19_RS16395	COG0732	type I restriction modification DNA specificity domain
C6N19_RS16420	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6N19_RS16480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N19_RS16495	COG0583	DNA-binding transcription factor activity
C6N19_RS16530	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS16535	COG0583	DNA-binding transcription factor activity
C6N19_RS16555	COG0583	DNA-binding transcription factor activity
C6N19_RS16560	COG1053	succinate dehydrogenase
C6N19_RS16575	COG1309	transcriptional regulator
C6N19_RS16585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6N19_RS16595	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS16600	COG0583	DNA-binding transcription factor activity
C6N19_RS16605	COG1063	alcohol dehydrogenase
C6N19_RS16620	COG0582	viral genome integration into host DNA
C6N19_RS16800	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N19_RS16800	COG3409	Peptidoglycan-binding domain 1 protein
C6N19_RS16845	COG4695	Portal protein
C6N19_RS16885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C6N19_RS16890	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C6N19_RS16895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N19_RS16915	COG2132	Multicopper oxidase
C6N19_RS16925	COG0561	phosphatase activity
C6N19_RS16930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6N19_RS16940	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C6N19_RS16955	COG1214	PFAM Peptidase M22, glycoprotease
C6N19_RS17020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6N19_RS17025	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C6N19_RS17030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C6N19_RS17090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N19_RS17100	COG1846	Transcriptional regulator
C6N19_RS17105	COG1764	response to oxidative stress
C6N19_RS17145	COG0037	tRNA processing
C6N19_RS17155	COG0248	Ppx GppA phosphatase
C6N19_RS17185	COG0072	phenylalanine-tRNA ligase activity
C6N19_RS17210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C6N19_RS17230	COG1238	metal cluster binding
C6N19_RS17235	COG0625	glutathione transferase activity
C6N19_RS17255	COG0318	PFAM AMP-dependent synthetase and ligase
C6N19_RS17260	COG3028	Belongs to the UPF0307 family
C6N19_RS17265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N19_RS17285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6N19_RS17290	COG0617	tRNA 3'-terminal CCA addition
C6N19_RS17295	COG1555	photosystem II stabilization
C6N19_RS17300	COG3956	TIGRFAM MazG family protein
C6N19_RS17310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N19_RS17325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N19_RS17330	COG5002	protein histidine kinase activity
C6N19_RS17330	COG2205	protein histidine kinase activity
C6N19_RS17330	COG0784	Response regulator, receiver
C6N19_RS17335	COG1024	Enoyl-CoA hydratase
C6N19_RS17340	COG2084	Dehydrogenase
C6N19_RS17345	COG3622	Belongs to the hyi family
C6N19_RS17380	COG0697	spore germination
C6N19_RS17390	COG2814	Major facilitator Superfamily
C6N19_RS17465	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N19_RS17490	COG2132	Multicopper oxidase
C6N19_RS17505	COG2205	protein histidine kinase activity
C6N19_RS17560	COG2801	Transposase and inactivated derivatives
C6N19_RS17595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N19_RS17625	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6N19_RS17635	COG0084	hydrolase, TatD family'
C6N19_RS17650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C6N19_RS17670	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C6N19_RS17675	COG0440	acetolactate synthase activity
C6N19_RS17680	COG0028	Belongs to the TPP enzyme family
C6N19_RS17700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N19_RS17705	COG1136	(ABC) transporter
C6N19_RS17705	COG0577	efflux transmembrane transporter activity
C6N19_RS17735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C6N19_RS17740	COG1162	GTPase activity
C6N19_RS17750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6N19_RS17770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N19_RS17790	COG1426	Protein conserved in bacteria
C6N19_RS17825	COG0793	Belongs to the peptidase S41A family
C6N19_RS17840	COG2267	carboxylic ester hydrolase activity
C6N19_RS17850	COG1012	belongs to the aldehyde dehydrogenase family
C6N19_RS17855	COG3265	gluconokinase activity
C6N19_RS17865	COG0800	Aldolase
C6N19_RS17880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N19_RS17885	COG0857	belongs to the CobB CobQ family
C6N19_RS17885	COG0280	phosphate acetyltransferase
C6N19_RS17890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N19_RS17890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N19_RS17910	COG0740	serine-type endopeptidase activity
C6N19_RS17920	COG4774	siderophore transport
C6N19_RS17930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C6N19_RS17940	COG2813	Specifically methylates the guanine in position
C6N19_RS17940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N19_RS17955	COG1484	DNA-dependent DNA replication
C6N19_RS17960	COG4584	PFAM Integrase catalytic
C6N19_RS17980	COG2826	transposase and inactivated derivatives, IS30 family
C6N19_RS17985	COG1002	Type II restriction enzyme, methylase subunits
C6N19_RS17990	COG1061	Type III restriction enzyme res subunit
C6N19_RS18000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N19_RS18095	COG0788	formyltetrahydrofolate deformylase activity
C6N19_RS18120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N19_RS18120	COG4651	solute:proton antiporter activity
C6N19_RS18140	COG0724	RNA recognition motif
C6N19_RS18145	COG0210	DNA helicase
C6N19_RS18170	COG1733	regulation of RNA biosynthetic process
C6N19_RS18175	COG0604	alcohol dehydrogenase
C6N19_RS18180	COG2900	Belongs to the SlyX family
C6N19_RS18185	COG0488	(ABC) transporter
C6N19_RS18195	COG1560	Kdo2-lipid A biosynthetic process
C6N19_RS18205	COG1301	dicarboxylic acid transport
C6N19_RS18260	COG0473	3-isopropylmalate dehydrogenase activity
C6N19_RS18285	COG0583	DNA-binding transcription factor activity
C6N19_RS18325	COG0583	DNA-binding transcription factor activity
C6N19_RS18335	COG0625	glutathione transferase activity
C6N19_RS18340	COG2378	regulation of single-species biofilm formation
C6N19_RS18345	COG0546	phosphoglycolate phosphatase activity
C6N19_RS18360	COG1530	ribonuclease E activity
C6N19_RS18365	COG0318	PFAM AMP-dependent synthetase and ligase
C6N19_RS18380	COG0583	DNA-binding transcription factor activity
C6N19_RS18385	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS18390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6N19_RS18400	COG0534	Mate efflux family protein
C6N19_RS18415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6N19_RS18440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N19_RS18440	COG0493	'glutamate synthase
C6N19_RS18450	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C6N19_RS18455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N19_RS18470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6N19_RS18480	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6N19_RS18480	COG0644	oxidoreductase
C6N19_RS18495	COG4535	Mg2 and Co2 transporter CorC
C6N19_RS18505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N19_RS18525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6N19_RS18535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C6N19_RS18545	COG0484	heat shock protein binding
C6N19_RS18550	COG0789	Transcriptional regulator
C6N19_RS18555	COG0598	Magnesium transport protein CorA
C6N19_RS18560	COG1185	polyribonucleotide nucleotidyltransferase activity
C6N19_RS18570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N19_RS18575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N19_RS18580	COG1074	ATP-dependent DNA helicase activity
C6N19_RS18585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6N19_RS18605	COG2226	methyltransferase
C6N19_RS18615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6N19_RS18620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N19_RS18630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C6N19_RS18645	COG2111	Na H antiporter
C6N19_RS18645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N19_RS18650	COG1006	Multisubunit Na H antiporter MnhC subunit
C6N19_RS18655	COG0651	ATP synthesis coupled electron transport
C6N19_RS18660	COG1863	multisubunit Na H antiporter MnhE subunit
C6N19_RS18665	COG2212	antiporter activity
C6N19_RS18670	COG1320	monovalent cation:proton antiporter activity
C6N19_RS18675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C6N19_RS18685	COG0195	Participates in both transcription termination and antitermination
C6N19_RS18735	COG0237	dephospho-CoA kinase activity
C6N19_RS18745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N19_RS18760	COG0497	DNA recombination
C6N19_RS18770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C6N19_RS18805	COG2169	Transcriptional regulator
C6N19_RS18805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N19_RS18810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6N19_RS18885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C6N19_RS18900	COG0326	Molecular chaperone. Has ATPase activity
C6N19_RS18915	COG2056	Na+-H+ antiporter family
C6N19_RS18985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C6N19_RS19015	COG0546	phosphoglycolate phosphatase activity
C6N19_RS19020	COG1716	ATPase activity
C6N19_RS19065	COG0181	hydroxymethylbilane synthase activity
C6N19_RS19075	COG3275	phosphorelay sensor kinase activity
C6N19_RS19095	COG1538	Outer membrane efflux protein
C6N19_RS19105	COG0697	spore germination
C6N19_RS19125	COG0494	nUDIX hydrolase
C6N19_RS19130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6N19_RS19135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6N19_RS19140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6N19_RS19145	COG0772	Belongs to the SEDS family
C6N19_RS19170	COG4974	Belongs to the 'phage' integrase family
C6N19_RS19175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N19_RS19185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6N19_RS19195	COG2197	response regulator
C6N19_RS19210	COG0793	Belongs to the peptidase S41A family
C6N19_RS19215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C6N19_RS19220	COG0795	lipopolysaccharide-transporting ATPase activity
C6N19_RS19260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N19_RS19260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N19_RS19270	COG0004	ammonium transporteR
C6N19_RS19275	COG0347	Belongs to the P(II) protein family
C6N19_RS19285	COG0606	chelatase, subunit chli
C6N19_RS19290	COG0431	NADPH-dependent FMN reductase
C6N19_RS19295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS19300	COG0235	Class ii aldolase
C6N19_RS19305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N19_RS19325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6N19_RS19340	COG0318	PFAM AMP-dependent synthetase and ligase
C6N19_RS19350	COG0477	Major facilitator Superfamily
C6N19_RS19355	COG2860	membrane
C6N19_RS19365	COG1253	flavin adenine dinucleotide binding
C6N19_RS19375	COG2814	Major facilitator Superfamily
C6N19_RS19385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N19_RS19425	COG0655	NAD(P)H dehydrogenase (quinone) activity
C6N19_RS19440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N19_RS19470	COG1309	transcriptional regulator
C6N19_RS19505	COG0758	DNA mediated transformation
C6N19_RS19515	COG0697	spore germination
C6N19_RS19520	COG1309	transcriptional regulator
C6N19_RS19535	COG0386	Belongs to the glutathione peroxidase family
C6N19_RS19550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C6N19_RS19560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C6N19_RS19600	COG1121	(ABC) transporter
C6N19_RS19605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N19_RS19610	COG1280	lysine exporter protein (LysE YggA)
C6N19_RS19615	COG2837	iron assimilation
C6N19_RS19620	COG0281	malic enzyme
C6N19_RS19645	COG3328	transposase activity
C6N19_RS19675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6N19_RS19675	COG0519	Catalyzes the synthesis of GMP from XMP
C6N19_RS19680	COG4399	Belongs to the UPF0754 family
C6N19_RS19685	COG2259	Doxx family
C6N19_RS19690	COG0586	Pfam SNARE associated Golgi protein
C6N19_RS19705	COG1192	Involved in chromosome partitioning
C6N19_RS19715	COG0271	Belongs to the BolA IbaG family
C6N19_RS19745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6N19_RS19745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N19_RS19745	COG3321	synthase
C6N19_RS19745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6N19_RS19750	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS19755	COG0318	PFAM AMP-dependent synthetase and ligase
C6N19_RS19760	COG2197	response regulator
C6N19_RS19770	COG3916	Acyl-homoserine-lactone synthase
C6N19_RS19775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N19_RS19785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N19_RS19790	COG1113	amino acid transport
C6N19_RS19795	COG0697	spore germination
C6N19_RS19800	COG0477	Major facilitator Superfamily
C6N19_RS19805	COG1024	Enoyl-CoA hydratase
C6N19_RS19810	COG1024	Enoyl-CoA hydratase
C6N19_RS19815	COG1960	acyl-CoA dehydrogenase activity
C6N19_RS19820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N19_RS19840	COG1113	amino acid transport
C6N19_RS19845	COG1113	amino acid transport
C6N19_RS19850	COG0251	oxidation-reduction process
C6N19_RS19890	COG0564	pseudouridine synthase activity
C6N19_RS19970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6N19_RS19985	COG1802	Transcriptional regulator
C6N19_RS19995	COG1448	Aminotransferase
C6N19_RS20000	COG0277	FAD linked oxidase domain protein
C6N19_RS20010	COG2186	Transcriptional regulator
C6N19_RS20020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N19_RS20035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6N19_RS20040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6N19_RS20075	COG1091	dTDP-4-dehydrorhamnose reductase activity
C6N19_RS20100	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6N19_RS20130	COG0728	peptidoglycan biosynthetic process
C6N19_RS20135	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6N19_RS20190	COG0546	phosphoglycolate phosphatase activity
C6N19_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
C6N19_RS20210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6N19_RS20210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6N19_RS20215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N19_RS20220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N19_RS20225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N19_RS20230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N19_RS20235	COG1116	anion transmembrane transporter activity
C6N19_RS20240	COG1309	transcriptional regulator
C6N19_RS20245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6N19_RS20255	COG0196	riboflavin kinase activity
C6N19_RS20260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C6N19_RS20270	COG1047	Peptidyl-prolyl cis-trans
C6N19_RS20310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N19_RS20315	COG0657	acetylesterase activity
C6N19_RS20365	COG2951	lytic endotransglycosylase activity
C6N19_RS20370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6N19_RS20385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6N19_RS20395	COG0671	phosphoesterase, PA-phosphatase related
C6N19_RS20400	COG0861	Integral membrane protein TerC family
C6N19_RS20410	COG0754	glutathionylspermidine amidase activity
C6N19_RS20420	COG0402	S-adenosylhomocysteine deaminase activity
C6N19_RS20435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N19_RS20455	COG0706	membrane insertase activity