locus-tag	class	description
C6N17_RS00010	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C6N17_RS00045	COG2184	nucleotidyltransferase activity
C6N17_RS00090	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C6N17_RS00090	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C6N17_RS00150	COG0697	spore germination
C6N17_RS00155	COG0477	Major facilitator Superfamily
C6N17_RS00185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C6N17_RS00200	COG1979	alcohol dehydrogenase
C6N17_RS00210	COG1902	pentaerythritol trinitrate reductase activity
C6N17_RS00220	COG1309	transcriptional regulator
C6N17_RS00225	COG2130	NADP-dependent
C6N17_RS00240	COG0582	viral genome integration into host DNA
C6N17_RS00270	COG0604	alcohol dehydrogenase
C6N17_RS00300	COG1192	Involved in chromosome partitioning
C6N17_RS00305	COG1475	DNA binding
C6N17_RS00310	COG1785	Belongs to the alkaline phosphatase family
C6N17_RS00460	COG3077	Addiction module antitoxin, RelB DinJ family
C6N17_RS00465	COG0488	(ABC) transporter
C6N17_RS00470	COG3173	Aminoglycoside phosphotransferase
C6N17_RS00510	COG0745	RESPONSE REGULATOR receiver
C6N17_RS00515	COG5002	protein histidine kinase activity
C6N17_RS00525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N17_RS00545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6N17_RS00570	COG0592	DNA-directed DNA polymerase activity
C6N17_RS00580	COG0187	DNA topoisomerase II activity
C6N17_RS00595	COG0488	(ABC) transporter
C6N17_RS00620	COG0596	Alpha beta hydrolase
C6N17_RS00625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C6N17_RS00630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C6N17_RS00660	COG0625	glutathione transferase activity
C6N17_RS00670	COG0733	neurotransmitter:sodium symporter activity
C6N17_RS00710	COG2233	PERMEase
C6N17_RS00725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS00760	COG2814	Major facilitator Superfamily
C6N17_RS00765	COG0656	L-ascorbic acid biosynthetic process
C6N17_RS00770	COG0583	DNA-binding transcription factor activity
C6N17_RS00785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS00790	COG1064	alcohol dehydrogenase
C6N17_RS00795	COG2818	Glycosylase
C6N17_RS00810	COG1194	a g-specific adenine glycosylase
C6N17_RS00825	COG5487	UPF0391 membrane protein
C6N17_RS00830	COG2983	Belongs to the UPF0260 family
C6N17_RS00835	COG2133	pyrroloquinoline quinone binding
C6N17_RS00840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6N17_RS00845	COG2116	formate transmembrane transporter activity
C6N17_RS00865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N17_RS00870	COG1335	isochorismatase
C6N17_RS00875	COG0385	Bile acid
C6N17_RS00880	COG0534	Mate efflux family protein
C6N17_RS00885	COG1683	Conserved Protein
C6N17_RS00900	COG0346	lactoylglutathione lyase activity
C6N17_RS00905	COG0625	glutathione transferase activity
C6N17_RS00925	COG0523	cobalamin synthesis protein
C6N17_RS00945	COG2188	Transcriptional regulator
C6N17_RS00975	COG0010	Belongs to the arginase family
C6N17_RS01005	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS01020	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS01040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C6N17_RS01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6N17_RS01105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6N17_RS01110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C6N17_RS01190	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS01220	COG0534	Mate efflux family protein
C6N17_RS01225	COG0436	Aminotransferase
C6N17_RS01230	COG2733	membrane
C6N17_RS01245	COG2918	glutathione biosynthetic process
C6N17_RS01275	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS01295	COG3150	esterase
C6N17_RS01305	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
C6N17_RS01315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N17_RS01325	COG2233	PERMEase
C6N17_RS01330	COG2351	hydroxyisourate hydrolase activity
C6N17_RS01365	COG3706	GGDEF domain
C6N17_RS01380	COG1393	Belongs to the ArsC family
C6N17_RS01385	COG0708	Exodeoxyribonuclease III
C6N17_RS01415	COG0189	ligase activity
C6N17_RS01435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6N17_RS01445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6N17_RS01460	COG4942	peptidase
C6N17_RS01470	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N17_RS01480	COG2119	membrane
C6N17_RS01485	COG4774	siderophore transport
C6N17_RS01490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N17_RS01490	COG0426	domain, Protein
C6N17_RS01510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6N17_RS01530	COG1902	pentaerythritol trinitrate reductase activity
C6N17_RS01535	COG1519	Transferase
C6N17_RS01540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N17_RS01545	COG0668	transmembrane transport
C6N17_RS01555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N17_RS01560	COG1335	isochorismatase
C6N17_RS01565	COG1522	sequence-specific DNA binding
C6N17_RS01590	COG2205	protein histidine kinase activity
C6N17_RS01590	COG2198	Histidine kinase
C6N17_RS01590	COG0784	Response regulator, receiver
C6N17_RS01595	COG3162	membrane
C6N17_RS01600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N17_RS01610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N17_RS01635	COG1309	transcriptional regulator
C6N17_RS01655	COG0300	oxidoreductase activity
C6N17_RS01660	COG0789	Transcriptional regulator
C6N17_RS01665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6N17_RS01665	COG0351	phosphomethylpyrimidine kinase
C6N17_RS01665	COG0352	thiamine-phosphate diphosphorylase activity
C6N17_RS01675	COG2814	Major facilitator Superfamily
C6N17_RS01690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6N17_RS01700	COG1113	amino acid transport
C6N17_RS01710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N17_RS01715	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS01725	COG1335	isochorismatase
C6N17_RS01755	COG2814	Major facilitator Superfamily
C6N17_RS01760	COG0583	DNA-binding transcription factor activity
C6N17_RS01780	COG0667	Aldo Keto reductase
C6N17_RS01800	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS01830	COG1733	regulation of RNA biosynthetic process
C6N17_RS01845	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N17_RS01855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6N17_RS01860	COG2207	Transcriptional regulator
C6N17_RS01935	COG0582	viral genome integration into host DNA
C6N17_RS01995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N17_RS02010	COG0697	spore germination
C6N17_RS02035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6N17_RS02065	COG0427	acetyl-CoA hydrolase
C6N17_RS02090	COG0659	secondary active sulfate transmembrane transporter activity
C6N17_RS02095	COG4221	oxidoreductase activity
C6N17_RS02100	COG2873	o-acetylhomoserine
C6N17_RS02105	COG0488	(ABC) transporter
C6N17_RS02190	COG0833	amino acid
C6N17_RS02235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6N17_RS02240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6N17_RS02255	COG2226	methyltransferase
C6N17_RS02305	COG0069	glutamate synthase activity
C6N17_RS02305	COG0070	glutamate synthase
C6N17_RS02305	COG0067	glutamate synthase
C6N17_RS02310	COG0493	'glutamate synthase
C6N17_RS02320	COG1704	LemA family
C6N17_RS02325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6N17_RS02335	COG4969	Belongs to the N-Me-Phe pilin family
C6N17_RS02345	COG3328	transposase activity
C6N17_RS02355	COG3307	-O-antigen
C6N17_RS02380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N17_RS02395	COG0194	GDP metabolic process
C6N17_RS02445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C6N17_RS02455	COG0335	large ribosomal subunit rRNA binding
C6N17_RS02465	COG5380	lipid catabolic process
C6N17_RS02470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C6N17_RS02485	COG5006	permease, DMT superfamily
C6N17_RS02490	COG5006	permease, DMT superfamily
C6N17_RS02495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6N17_RS02500	COG0277	FAD linked oxidase domain protein
C6N17_RS02510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6N17_RS02515	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N17_RS02530	COG1289	transmembrane transporter activity
C6N17_RS02540	COG0628	permease
C6N17_RS02545	COG1192	Involved in chromosome partitioning
C6N17_RS02575	COG0833	amino acid
C6N17_RS02580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6N17_RS02585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N17_RS02595	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS02635	COG0583	DNA-binding transcription factor activity
C6N17_RS02650	COG5002	protein histidine kinase activity
C6N17_RS02670	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS02690	COG0752	glycyl-tRNA synthetase alpha subunit
C6N17_RS02715	COG0517	IMP dehydrogenase activity
C6N17_RS02720	COG1983	PspC domain protein
C6N17_RS02730	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS02745	COG0408	coproporphyrinogen oxidase activity
C6N17_RS02765	COG0513	Belongs to the DEAD box helicase family
C6N17_RS02775	COG1127	ABC transporter
C6N17_RS02780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6N17_RS02790	COG2854	intermembrane phospholipid transfer
C6N17_RS02800	COG0598	Magnesium transport protein CorA
C6N17_RS02810	COG0494	nUDIX hydrolase
C6N17_RS02815	COG1040	competence protein
C6N17_RS02820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6N17_RS02835	COG2937	Belongs to the GPAT DAPAT family
C6N17_RS02840	COG1946	Acyl-CoA thioesterase
C6N17_RS02845	COG1301	dicarboxylic acid transport
C6N17_RS02860	COG1959	2 iron, 2 sulfur cluster binding
C6N17_RS02865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N17_RS02865	COG1017	nitric oxide dioxygenase activity
C6N17_RS02875	COG0433	COG0433 Predicted ATPase
C6N17_RS02880	COG0626	cystathionine gamma-synthase activity
C6N17_RS02895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C6N17_RS02900	COG0088	Forms part of the polypeptide exit tunnel
C6N17_RS03035	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS03040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6N17_RS03070	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS03085	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6N17_RS03090	COG0339	signal peptide processing
C6N17_RS03095	COG0557	exoribonuclease II activity
C6N17_RS03145	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6N17_RS03150	COG1295	ribonuclease BN
C6N17_RS03185	COG1702	phosphate starvation-inducible protein PhoH
C6N17_RS03195	COG0741	lytic transglycosylase activity
C6N17_RS03195	COG1196	nuclear chromosome segregation
C6N17_RS03195	COG0739	heme binding
C6N17_RS03225	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6N17_RS03230	COG1183	phosphatidylcholine synthase activity
C6N17_RS03275	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS03280	COG1309	transcriptional regulator
C6N17_RS03295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6N17_RS03300	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS03340	COG2969	positive regulation of protein catabolic process
C6N17_RS03345	COG0625	glutathione transferase activity
C6N17_RS03350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C6N17_RS03355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C6N17_RS03360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C6N17_RS03365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C6N17_RS03370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6N17_RS03390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6N17_RS03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N17_RS03405	COG1408	metallophosphoesterase
C6N17_RS03410	COG2885	chlorophyll binding
C6N17_RS03410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6N17_RS03415	COG2199	diguanylate cyclase activity
C6N17_RS03485	COG1607	acyl-coa hydrolase
C6N17_RS03520	COG2350	Protein conserved in bacteria
C6N17_RS03535	COG3781	membrane
C6N17_RS03545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6N17_RS03550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6N17_RS03560	COG1862	Preprotein translocase
C6N17_RS03595	COG2205	protein histidine kinase activity
C6N17_RS03595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N17_RS03595	COG0784	Response regulator, receiver
C6N17_RS03595	COG2198	Histidine kinase
C6N17_RS03600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C6N17_RS03615	COG0726	polysaccharide deacetylase
C6N17_RS03630	COG1216	Glycosyl transferase, family 2
C6N17_RS03680	COG0625	glutathione transferase activity
C6N17_RS03685	COG0583	DNA-binding transcription factor activity
C6N17_RS03690	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS03695	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS03705	COG2205	protein histidine kinase activity
C6N17_RS03710	COG0745	RESPONSE REGULATOR receiver
C6N17_RS03720	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C6N17_RS03740	COG2096	Adenosyltransferase
C6N17_RS03745	COG4206	TonB-dependent receptor
C6N17_RS03790	COG0285	dihydrofolate synthase activity
C6N17_RS03810	COG0450	alkyl hydroperoxide reductase
C6N17_RS03825	COG0477	Major facilitator Superfamily
C6N17_RS03830	COG1272	protein, Hemolysin III
C6N17_RS03840	COG2153	protein acetylation
C6N17_RS03860	COG0183	Belongs to the thiolase family
C6N17_RS03865	COG2207	Transcriptional regulator
C6N17_RS03885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N17_RS03905	COG0183	Belongs to the thiolase family
C6N17_RS03915	COG2885	chlorophyll binding
C6N17_RS03915	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6N17_RS03920	COG1690	Belongs to the RtcB family
C6N17_RS03925	COG0833	amino acid
C6N17_RS03935	COG2233	PERMEase
C6N17_RS03940	COG1217	gtp-binding protein TYPA
C6N17_RS03965	COG2094	Belongs to the DNA glycosylase MPG family
C6N17_RS03970	COG4772	TonB-dependent receptor
C6N17_RS03975	COG1902	pentaerythritol trinitrate reductase activity
C6N17_RS03980	COG0679	Auxin Efflux Carrier
C6N17_RS03990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N17_RS03995	COG0354	folic acid binding
C6N17_RS04015	COG2233	PERMEase
C6N17_RS04020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N17_RS04025	COG0251	oxidation-reduction process
C6N17_RS04030	COG1335	isochorismatase
C6N17_RS04035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N17_RS04040	COG0778	Nitroreductase
C6N17_RS04045	COG0596	Alpha beta hydrolase
C6N17_RS04050	COG3189	MarR family transcriptional regulator
C6N17_RS04055	COG2824	Alkylphosphonate utilization operon protein PhnA
C6N17_RS04060	COG3422	double-strand break repair
C6N17_RS04100	COG0840	transmembrane signaling receptor activity
C6N17_RS04120	COG5510	response to toxic substance
C6N17_RS04130	COG2832	Protein of unknown function (DUF454)
C6N17_RS04135	COG1376	ErfK ybiS ycfS ynhG family protein
C6N17_RS04165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C6N17_RS04175	COG1289	transmembrane transporter activity
C6N17_RS04180	COG2814	Major facilitator Superfamily
C6N17_RS04205	COG1115	amino acid carrier protein
C6N17_RS04210	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6N17_RS04215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N17_RS04220	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6N17_RS04225	COG3590	peptidase
C6N17_RS04250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6N17_RS04260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6N17_RS04265	COG1077	Cell shape determining protein MreB Mrl
C6N17_RS04270	COG1792	Involved in formation and maintenance of cell shape
C6N17_RS04275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6N17_RS04280	COG0424	maF-like protein
C6N17_RS04285	COG1530	ribonuclease E activity
C6N17_RS04295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N17_RS04315	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N17_RS04340	COG2207	Transcriptional regulator
C6N17_RS04370	COG3046	protein related to deoxyribodipyrimidine photolyase
C6N17_RS04380	COG1113	amino acid transport
C6N17_RS04385	COG2828	Protein conserved in bacteria
C6N17_RS04390	COG0142	geranyltranstransferase activity
C6N17_RS04395	COG2315	Protein conserved in bacteria
C6N17_RS04410	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6N17_RS04435	COG2194	sulfuric ester hydrolase activity
C6N17_RS04440	COG0745	RESPONSE REGULATOR receiver
C6N17_RS04445	COG0642	Histidine kinase
C6N17_RS04460	COG0004	ammonium transporteR
C6N17_RS04465	COG0583	DNA-binding transcription factor activity
C6N17_RS04490	COG0525	valine-tRNA ligase activity
C6N17_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS04510	COG0393	Putative heavy-metal-binding
C6N17_RS04515	COG0393	Putative heavy-metal-binding
C6N17_RS04520	COG1538	Outer membrane efflux protein
C6N17_RS04530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS04535	COG0671	phosphoesterase, PA-phosphatase related
C6N17_RS04560	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C6N17_RS04575	COG1648	precorrin-2 dehydrogenase activity
C6N17_RS04575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C6N17_RS04580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6N17_RS04615	COG0531	amino acid
C6N17_RS04630	COG0321	lipoyl(octanoyl) transferase activity
C6N17_RS04635	COG2921	Belongs to the UPF0250 family
C6N17_RS04675	COG2009	succinate dehydrogenase
C6N17_RS04680	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6N17_RS04685	COG1053	succinate dehydrogenase
C6N17_RS04690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6N17_RS04715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N17_RS04735	COG2354	Protein conserved in bacteria
C6N17_RS04740	COG2321	neutral zinc metallopeptidase
C6N17_RS04780	COG2843	Capsule synthesis protein
C6N17_RS04800	COG0589	response to stress
C6N17_RS04810	COG0251	oxidation-reduction process
C6N17_RS04815	COG1309	transcriptional regulator
C6N17_RS04830	COG0505	Belongs to the CarA family
C6N17_RS04865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6N17_RS04870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6N17_RS04915	COG2264	protein methyltransferase activity
C6N17_RS04925	COG0477	Major facilitator Superfamily
C6N17_RS04930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6N17_RS04945	COG1597	lipid kinase activity
C6N17_RS04950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6N17_RS04975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N17_RS04980	COG0584	glycerophosphoryl diester phosphodiesterase
C6N17_RS05000	COG0741	lytic transglycosylase activity
C6N17_RS05025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6N17_RS05055	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS05080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS05085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N17_RS05090	COG0778	Nitroreductase
C6N17_RS05105	COG1929	Belongs to the glycerate kinase type-1 family
C6N17_RS05110	COG0243	molybdopterin cofactor binding
C6N17_RS05115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C6N17_RS05120	COG3339	Conserved Protein
C6N17_RS05145	COG1115	amino acid carrier protein
C6N17_RS05150	COG1113	amino acid transport
C6N17_RS05160	COG0019	diaminopimelate decarboxylase activity
C6N17_RS05170	COG1280	lysine exporter protein (LysE YggA)
C6N17_RS05175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C6N17_RS05205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS05235	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6N17_RS05240	COG1136	(ABC) transporter
C6N17_RS05245	COG2333	competence protein COMEC
C6N17_RS05245	COG0658	competence protein
C6N17_RS05255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C6N17_RS05255	COG0616	signal peptide processing
C6N17_RS05260	COG0596	Alpha beta hydrolase
C6N17_RS05265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6N17_RS05275	COG0628	permease
C6N17_RS05315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N17_RS05335	COG0823	Involved in the tonB-independent uptake of proteins
C6N17_RS05355	COG0824	Thioesterase
C6N17_RS05360	COG1473	amidohydrolase
C6N17_RS05380	COG0047	phosphoribosylformylglycinamidine synthase activity
C6N17_RS05380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6N17_RS05385	COG2814	Major facilitator Superfamily
C6N17_RS05390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N17_RS05395	COG1024	Enoyl-CoA hydratase
C6N17_RS05400	COG1056	cytidyltransferase-related domain
C6N17_RS05400	COG1051	belongs to the nudix hydrolase family
C6N17_RS05415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6N17_RS05430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C6N17_RS05445	COG4625	pathogenesis
C6N17_RS05450	COG0583	DNA-binding transcription factor activity
C6N17_RS05455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6N17_RS05460	COG4208	sulfate ABC transporter
C6N17_RS05465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6N17_RS05475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6N17_RS05480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N17_RS05485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6N17_RS05505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N17_RS05515	COG0481	GTPase activity
C6N17_RS05520	COG0681	Belongs to the peptidase S26 family
C6N17_RS05530	COG0571	ribonuclease III activity
C6N17_RS05535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C6N17_RS05550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6N17_RS05560	COG4221	oxidoreductase activity
C6N17_RS05590	COG0436	Aminotransferase
C6N17_RS05610	COG0556	nucleotide-excision repair
C6N17_RS05620	COG2962	Rard protein
C6N17_RS05665	COG2070	2-Nitropropane dioxygenase
C6N17_RS05680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N17_RS05695	COG1215	transferase activity, transferring glycosyl groups
C6N17_RS05710	COG0415	Belongs to the DNA photolyase family
C6N17_RS05720	COG1252	NADH dehydrogenase
C6N17_RS05725	COG1686	Belongs to the peptidase S11 family
C6N17_RS05740	COG1187	pseudouridine synthase activity
C6N17_RS05755	COG0477	Major facilitator Superfamily
C6N17_RS05760	COG0583	DNA-binding transcription factor activity
C6N17_RS05765	COG1823	symporter activity
C6N17_RS05775	COG0612	Peptidase, M16
C6N17_RS05800	COG0352	thiamine-phosphate diphosphorylase activity
C6N17_RS05835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N17_RS05850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N17_RS05855	COG0076	glutamate decarboxylase activity
C6N17_RS05865	COG1522	sequence-specific DNA binding
C6N17_RS05870	COG3961	Belongs to the TPP enzyme family
C6N17_RS05875	COG1113	amino acid transport
C6N17_RS05880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N17_RS05885	COG0573	inorganic phosphate transmembrane transporter activity
C6N17_RS05895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6N17_RS05900	COG0616	signal peptide processing
C6N17_RS05935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6N17_RS05940	COG1686	Belongs to the peptidase S11 family
C6N17_RS05965	COG0583	DNA-binding transcription factor activity
C6N17_RS05970	COG1067	ATP-dependent peptidase activity
C6N17_RS06010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C6N17_RS06015	COG1966	Carbon starvation protein
C6N17_RS06020	COG2879	small protein
C6N17_RS06065	COG1741	Belongs to the pirin family
C6N17_RS06080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N17_RS06085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N17_RS06090	COG4605	iron ion homeostasis
C6N17_RS06095	COG4604	ABC transporter, ATP-binding protein
C6N17_RS06100	COG4607	ABC-type enterochelin transport system periplasmic component
C6N17_RS06105	COG4774	siderophore transport
C6N17_RS06115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N17_RS06120	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6N17_RS06125	COG1535	isochorismatase
C6N17_RS06125	COG3433	isochorismatase activity
C6N17_RS06140	COG1132	(ABC) transporter
C6N17_RS06145	COG1132	(ABC) transporter
C6N17_RS06150	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C6N17_RS06155	COG2977	Belongs to the P-Pant transferase superfamily
C6N17_RS06160	COG1169	isochorismate synthase
C6N17_RS06180	COG3739	integral membrane protein
C6N17_RS06200	COG0302	gtp cyclohydrolase
C6N17_RS06210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6N17_RS06220	COG2840	Smr protein MutS2
C6N17_RS06255	COG0512	Glutamine amidotransferase of anthranilate synthase
C6N17_RS06270	COG0174	glutamine synthetase
C6N17_RS06280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C6N17_RS06315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N17_RS06320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N17_RS06325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N17_RS06345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N17_RS06350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6N17_RS06355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C6N17_RS06370	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS06375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C6N17_RS06380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N17_RS06390	COG2223	nitrite transmembrane transporter activity
C6N17_RS06400	COG0024	Methionine aminopeptidase
C6N17_RS06405	COG0052	Belongs to the universal ribosomal protein uS2 family
C6N17_RS06445	COG2951	lytic endotransglycosylase activity
C6N17_RS06450	COG0772	Belongs to the SEDS family
C6N17_RS06465	COG0842	Transport permease protein
C6N17_RS06470	COG1131	(ABC) transporter
C6N17_RS06515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N17_RS06530	COG4215	(ABC) transporter
C6N17_RS06535	COG4160	amino acid transport
C6N17_RS06540	COG4598	ABC transporter
C6N17_RS06550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N17_RS06555	COG0826	peptidase U32
C6N17_RS06560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS06565	COG0384	phenazine biosynthesis protein PhzF
C6N17_RS06575	COG1720	tRNA m6t6A37 methyltransferase activity
C6N17_RS06585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6N17_RS06600	COG0642	Histidine kinase
C6N17_RS06610	COG0494	nUDIX hydrolase
C6N17_RS06620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N17_RS06625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C6N17_RS06630	COG3139	Protein of unknown function (DUF1315)
C6N17_RS06635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6N17_RS06645	COG1301	dicarboxylic acid transport
C6N17_RS06650	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS06665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6N17_RS06675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6N17_RS06680	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6N17_RS06700	COG1690	Belongs to the RtcB family
C6N17_RS06705	COG1234	tRNA 3'-trailer cleavage
C6N17_RS06710	COG4650	regulator
C6N17_RS06740	COG2363	Small membrane protein
C6N17_RS06760	COG0513	Belongs to the DEAD box helicase family
C6N17_RS06770	COG0778	Nitroreductase
C6N17_RS06800	COG1286	toxin biosynthetic process
C6N17_RS06825	COG4783	chaperone-mediated protein folding
C6N17_RS06830	COG1610	YqeY-like protein
C6N17_RS06885	COG1278	Cold shock
C6N17_RS06900	COG3243	poly(R)-hydroxyalkanoic acid synthase
C6N17_RS06905	COG0786	glutamate:sodium symporter activity
C6N17_RS06910	COG0475	glutathione-regulated potassium exporter activity
C6N17_RS06910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N17_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS06965	COG1309	transcriptional regulator
C6N17_RS06975	COG2985	domain, Protein
C6N17_RS06990	COG2995	paraquat-inducible protein a
C6N17_RS06995	COG3008	intermembrane lipid transfer
C6N17_RS06995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6N17_RS07005	COG2351	hydroxyisourate hydrolase activity
C6N17_RS07045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6N17_RS07055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6N17_RS07060	COG0642	Histidine kinase
C6N17_RS07065	COG0745	RESPONSE REGULATOR receiver
C6N17_RS07080	COG1794	racemase activity, acting on amino acids and derivatives
C6N17_RS07120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N17_RS07125	COG2011	ABC-type metal ion transport system permease component
C6N17_RS07130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N17_RS07140	COG0151	Belongs to the GarS family
C6N17_RS07150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C6N17_RS07180	COG2308	Evidence 4 Homologs of previously reported genes of
C6N17_RS07190	COG1305	Transglutaminase-like
C6N17_RS07200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6N17_RS07205	COG0305	Participates in initiation and elongation during chromosome replication
C6N17_RS07230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6N17_RS07235	COG1845	cytochrome c oxidase, subunit III
C6N17_RS07240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6N17_RS07275	COG0583	DNA-binding transcription factor activity
C6N17_RS07290	COG2890	protein-(glutamine-N5) methyltransferase activity
C6N17_RS07295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N17_RS07300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N17_RS07315	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS07320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N17_RS07335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6N17_RS07345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C6N17_RS07350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C6N17_RS07355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C6N17_RS07360	COG2205	protein histidine kinase activity
C6N17_RS07365	COG0745	RESPONSE REGULATOR receiver
C6N17_RS07370	COG0174	glutamine synthetase
C6N17_RS07385	COG0477	Major facilitator Superfamily
C6N17_RS07390	COG0729	surface antigen
C6N17_RS07420	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS07430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N17_RS07435	COG2814	Major facilitator Superfamily
C6N17_RS07445	COG0583	DNA-binding transcription factor activity
C6N17_RS07460	COG1187	pseudouridine synthase activity
C6N17_RS07480	COG0802	atpase or kinase
C6N17_RS07485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C6N17_RS07495	COG1923	regulation of RNA biosynthetic process
C6N17_RS07500	COG0697	spore germination
C6N17_RS07515	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6N17_RS07525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6N17_RS07530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6N17_RS07530	COG0519	Catalyzes the synthesis of GMP from XMP
C6N17_RS07535	COG4302	ethanolamine ammonia-lyase activity
C6N17_RS07545	COG3328	transposase activity
C6N17_RS07555	COG0531	amino acid
C6N17_RS07575	COG1454	alcohol dehydrogenase
C6N17_RS07580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N17_RS07605	COG0308	aminopeptidase N
C6N17_RS07645	COG1605	Chorismate mutase
C6N17_RS07670	COG4772	TonB-dependent receptor
C6N17_RS07675	COG4774	siderophore transport
C6N17_RS07730	COG3772	lysozyme
C6N17_RS07755	COG0583	DNA-binding transcription factor activity
C6N17_RS07780	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS07800	COG0488	(ABC) transporter
C6N17_RS07805	COG0589	response to stress
C6N17_RS07825	COG3135	benzoate transporter
C6N17_RS07830	COG1522	sequence-specific DNA binding
C6N17_RS07840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N17_RS07845	COG0583	DNA-binding transcription factor activity
C6N17_RS07855	COG0183	Belongs to the thiolase family
C6N17_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS07865	COG2030	dehydratase
C6N17_RS07870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N17_RS07895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6N17_RS07905	COG0824	Thioesterase
C6N17_RS07910	COG1454	alcohol dehydrogenase
C6N17_RS07925	COG1335	isochorismatase
C6N17_RS07945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6N17_RS07975	COG0069	glutamate synthase activity
C6N17_RS08000	COG2814	Major facilitator Superfamily
C6N17_RS08015	COG0511	ligase activity, forming carbon-carbon bonds
C6N17_RS08040	COG4264	IucA IucC family
C6N17_RS08050	COG4264	IucA IucC family
C6N17_RS08055	COG2423	ornithine cyclodeaminase activity
C6N17_RS08060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N17_RS08065	COG1116	anion transmembrane transporter activity
C6N17_RS08065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N17_RS08080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N17_RS08080	COG2146	nitrite reductase [NAD(P)H] activity
C6N17_RS08085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N17_RS08090	COG0243	molybdopterin cofactor binding
C6N17_RS08100	COG0243	molybdopterin cofactor binding
C6N17_RS08105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C6N17_RS08120	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6N17_RS08120	COG0315	cyclic pyranopterin monophosphate synthase activity
C6N17_RS08125	COG0303	'Molybdopterin
C6N17_RS08135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS08140	COG0697	spore germination
C6N17_RS08165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6N17_RS08235	COG2204	response regulator
C6N17_RS08240	COG3852	Histidine kinase
C6N17_RS08265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6N17_RS08270	COG0575	Belongs to the CDS family
C6N17_RS08305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6N17_RS08320	COG2137	regulation of response to DNA damage stimulus
C6N17_RS08330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6N17_RS08335	COG1011	Hydrolase
C6N17_RS08350	COG1522	sequence-specific DNA binding
C6N17_RS08360	COG1113	amino acid transport
C6N17_RS08380	COG0659	secondary active sulfate transmembrane transporter activity
C6N17_RS08425	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6N17_RS08425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N17_RS08425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N17_RS08430	COG1105	Belongs to the carbohydrate kinase PfkB family
C6N17_RS08435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N17_RS08435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N17_RS08455	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C6N17_RS08465	COG0024	Methionine aminopeptidase
C6N17_RS08470	COG0583	DNA-binding transcription factor activity
C6N17_RS08480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6N17_RS08485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N17_RS08490	COG0517	IMP dehydrogenase activity
C6N17_RS08490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6N17_RS08515	COG0552	protein localization to endoplasmic reticulum
C6N17_RS08540	COG4890	Cyd operon protein YbgT
C6N17_RS08545	COG1294	oxidase, subunit
C6N17_RS08560	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6N17_RS08570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N17_RS08585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N17_RS08590	COG0569	domain protein
C6N17_RS08595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N17_RS08625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C6N17_RS08630	COG0542	response to heat
C6N17_RS08655	COG1902	pentaerythritol trinitrate reductase activity
C6N17_RS08655	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N17_RS08695	COG0148	phosphopyruvate hydratase activity
C6N17_RS08700	COG2323	membrane
C6N17_RS08710	COG4773	Receptor
C6N17_RS08715	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C6N17_RS08725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N17_RS08730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N17_RS08735	COG0183	Belongs to the thiolase family
C6N17_RS08740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6N17_RS08745	COG0596	Alpha beta hydrolase
C6N17_RS08750	COG2271	Major facilitator Superfamily
C6N17_RS08755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N17_RS08760	COG3485	protocatechuate 3,4-dioxygenase
C6N17_RS08765	COG3485	protocatechuate 3,4-dioxygenase
C6N17_RS08770	COG0710	3-dehydroquinate dehydratase activity
C6N17_RS08775	COG3420	alginic acid biosynthetic process
C6N17_RS08780	COG3659	wide pore channel activity
C6N17_RS08785	COG4993	Dehydrogenase
C6N17_RS08795	COG2391	methyltransferase activity
C6N17_RS08810	COG1414	Transcriptional regulator
C6N17_RS08815	COG0583	DNA-binding transcription factor activity
C6N17_RS08820	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS08845	COG2814	Major facilitator Superfamily
C6N17_RS08855	COG0154	amidase activity
C6N17_RS08875	COG4638	Rieske (2fe-2S)
C6N17_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS08895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N17_RS08905	COG3733	amine oxidase
C6N17_RS08915	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS08920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N17_RS08925	COG0183	Belongs to the thiolase family
C6N17_RS08930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N17_RS08935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N17_RS08945	COG4829	muconolactone delta-isomerase
C6N17_RS08950	COG4948	Mandelate Racemase Muconate Lactonizing
C6N17_RS08955	COG0583	DNA-binding transcription factor activity
C6N17_RS08965	COG2186	Transcriptional regulator
C6N17_RS08985	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS08990	COG2351	hydroxyisourate hydrolase activity
C6N17_RS08995	COG2233	PERMEase
C6N17_RS09005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N17_RS09010	COG2186	Transcriptional regulator
C6N17_RS09025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N17_RS09035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N17_RS09055	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N17_RS09055	COG1902	pentaerythritol trinitrate reductase activity
C6N17_RS09095	COG1309	transcriptional regulator
C6N17_RS09100	COG0583	DNA-binding transcription factor activity
C6N17_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS09125	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS09135	COG0318	PFAM AMP-dependent synthetase and ligase
C6N17_RS09180	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS09215	COG0583	DNA-binding transcription factor activity
C6N17_RS09240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6N17_RS09245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C6N17_RS09260	COG2831	hemolysin activation secretion protein
C6N17_RS09330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N17_RS09335	COG1120	ATPase activity
C6N17_RS09345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N17_RS09395	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C6N17_RS09455	COG4628	conserved protein (DUF2132)
C6N17_RS09560	COG3539	Fimbrial protein
C6N17_RS09585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C6N17_RS09595	COG0753	catalase activity
C6N17_RS09615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N17_RS09625	COG2205	protein histidine kinase activity
C6N17_RS09630	COG0745	RESPONSE REGULATOR receiver
C6N17_RS09635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS09640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N17_RS09695	COG3433	isochorismatase activity
C6N17_RS09695	COG1535	isochorismatase
C6N17_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS09705	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C6N17_RS09710	COG4149	molybdate abc transporter
C6N17_RS09715	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6N17_RS09735	COG4638	Rieske (2fe-2S)
C6N17_RS09740	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6N17_RS09745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N17_RS09745	COG0543	2 iron, 2 sulfur cluster binding
C6N17_RS09760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N17_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS09790	COG2207	Transcriptional regulator
C6N17_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS09800	COG2610	gluconate transmembrane transporter activity
C6N17_RS09845	COG0583	DNA-binding transcription factor activity
C6N17_RS09860	COG2031	fatty acid transporter
C6N17_RS09865	COG0183	Belongs to the thiolase family
C6N17_RS09870	COG0583	DNA-binding transcription factor activity
C6N17_RS09875	COG0583	DNA-binding transcription factor activity
C6N17_RS09890	COG1027	Aspartate ammonia-lyase
C6N17_RS09900	COG0477	Major facilitator Superfamily
C6N17_RS09910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N17_RS09915	COG1733	regulation of RNA biosynthetic process
C6N17_RS09920	COG3708	Transcriptional regulator
C6N17_RS09920	COG2207	Transcriptional regulator
C6N17_RS09935	COG0730	response to heat
C6N17_RS09955	COG3781	membrane
C6N17_RS09960	COG1063	alcohol dehydrogenase
C6N17_RS09970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N17_RS09975	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N17_RS09980	COG0022	dehydrogenase e1 component
C6N17_RS09985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6N17_RS09990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C6N17_RS10005	COG3706	GGDEF domain
C6N17_RS10010	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS10030	COG0133	tryptophan synthase activity
C6N17_RS10040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6N17_RS10070	COG0583	DNA-binding transcription factor activity
C6N17_RS10075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N17_RS10085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C6N17_RS10145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6N17_RS10150	COG4773	Receptor
C6N17_RS10175	COG0730	response to heat
C6N17_RS10180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6N17_RS10200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C6N17_RS10230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6N17_RS10245	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS10250	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS10255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N17_RS10260	COG2207	Transcriptional regulator
C6N17_RS10265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N17_RS10270	COG0776	regulation of translation
C6N17_RS10295	COG0822	iron-sulfur transferase activity
C6N17_RS10300	COG0316	Belongs to the HesB IscA family
C6N17_RS10330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6N17_RS10350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C6N17_RS10355	COG0702	epimerase
C6N17_RS10395	COG0601	transmembrane transport
C6N17_RS10400	COG0339	signal peptide processing
C6N17_RS10405	COG4166	transmembrane transport
C6N17_RS10450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6N17_RS10455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6N17_RS10470	COG3328	transposase activity
C6N17_RS10475	COG2431	L-lysine efflux transmembrane transporter activity
C6N17_RS10490	COG0776	regulation of translation
C6N17_RS10555	COG0084	hydrolase, TatD family'
C6N17_RS10575	COG1663	tetraacyldisaccharide 4'-kinase activity
C6N17_RS10580	COG1132	(ABC) transporter
C6N17_RS10590	COG0811	peptide transport
C6N17_RS10595	COG1475	DNA binding
C6N17_RS10600	COG1192	Involved in chromosome partitioning
C6N17_RS10610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C6N17_RS10615	COG3178	'Phosphotransferase
C6N17_RS10625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N17_RS10650	COG0424	maF-like protein
C6N17_RS10655	COG2850	peptidyl-arginine hydroxylation
C6N17_RS10665	COG0640	Transcriptional regulator
C6N17_RS10675	COG3619	membrane
C6N17_RS10680	COG3122	Protein conserved in bacteria
C6N17_RS10685	COG1132	(ABC) transporter
C6N17_RS10705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6N17_RS10710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N17_RS10720	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N17_RS10720	COG0506	proline dehydrogenase activity
C6N17_RS10720	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6N17_RS10725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6N17_RS10740	COG3698	Phosphodiester glycosidase
C6N17_RS10750	COG2353	YceI-like domain
C6N17_RS10760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6N17_RS10805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6N17_RS10805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6N17_RS10830	COG3539	Fimbrial protein
C6N17_RS10865	COG0583	DNA-binding transcription factor activity
C6N17_RS10870	COG0697	spore germination
C6N17_RS10880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6N17_RS10915	COG1309	transcriptional regulator
C6N17_RS10930	COG1522	sequence-specific DNA binding
C6N17_RS10940	COG1126	abc transporter atp-binding protein
C6N17_RS10945	COG0765	amino acid transport
C6N17_RS10950	COG0765	amino acid transport
C6N17_RS10980	COG1464	Belongs to the NlpA lipoprotein family
C6N17_RS10990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N17_RS10995	COG2011	ABC-type metal ion transport system permease component
C6N17_RS11000	COG0012	GTP binding
C6N17_RS11025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6N17_RS11060	COG2207	Transcriptional regulator
C6N17_RS11060	COG1917	Cupin 2, conserved barrel domain protein
C6N17_RS11065	COG0386	Belongs to the glutathione peroxidase family
C6N17_RS11075	COG0436	Aminotransferase
C6N17_RS11080	COG1301	dicarboxylic acid transport
C6N17_RS11115	COG3634	alkyl hydroperoxide reductase activity
C6N17_RS11130	COG0583	DNA-binding transcription factor activity
C6N17_RS11135	COG0431	NADPH-dependent FMN reductase
C6N17_RS11140	COG0798	PFAM Bile acid sodium symporter
C6N17_RS11150	COG0640	Transcriptional regulator
C6N17_RS11165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C6N17_RS11185	COG1953	Uracil, thiamine, allantoin
C6N17_RS11195	COG2175	clavaminate synthase activity
C6N17_RS11200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N17_RS11215	COG0477	Major facilitator Superfamily
C6N17_RS11220	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS11240	COG1271	oxidase subunit
C6N17_RS11245	COG1294	oxidase, subunit
C6N17_RS11255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS11275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6N17_RS11295	COG3052	prosthetic group binding
C6N17_RS11300	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C6N17_RS11325	COG1346	cytolysis
C6N17_RS11335	COG0583	DNA-binding transcription factor activity
C6N17_RS11340	COG0625	glutathione transferase activity
C6N17_RS11345	COG0625	glutathione transferase activity
C6N17_RS11365	COG0583	DNA-binding transcription factor activity
C6N17_RS11380	COG1045	serine acetyltransferase
C6N17_RS11385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N17_RS11390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6N17_RS11395	COG1280	lysine exporter protein (LysE YggA)
C6N17_RS11410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N17_RS11415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N17_RS11425	COG0765	amino acid transport
C6N17_RS11430	COG0765	amino acid transport
C6N17_RS11450	COG2205	protein histidine kinase activity
C6N17_RS11450	COG0784	Response regulator, receiver
C6N17_RS11470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6N17_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS11535	COG0583	DNA-binding transcription factor activity
C6N17_RS11550	COG2814	Major facilitator Superfamily
C6N17_RS11565	COG0318	PFAM AMP-dependent synthetase and ligase
C6N17_RS11570	COG1309	transcriptional regulator
C6N17_RS11575	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS11580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6N17_RS11585	COG1024	Enoyl-CoA hydratase
C6N17_RS11590	COG4770	biotin carboxylase activity
C6N17_RS11600	COG0583	DNA-binding transcription factor activity
C6N17_RS11615	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS11625	COG2814	Major facilitator Superfamily
C6N17_RS11635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N17_RS11640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N17_RS11645	COG2814	Major facilitator Superfamily
C6N17_RS11650	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS11655	COG1024	Enoyl-CoA hydratase
C6N17_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS11665	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N17_RS11670	COG0183	Belongs to the thiolase family
C6N17_RS11680	COG2814	Major facilitator Superfamily
C6N17_RS11690	COG1024	Enoyl-CoA hydratase
C6N17_RS11705	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS11710	COG2814	Major facilitator Superfamily
C6N17_RS11715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N17_RS11720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C6N17_RS11735	COG3842	ATPase activity
C6N17_RS11740	COG1840	ABC-type Fe3 transport system, periplasmic component
C6N17_RS11750	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS11760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N17_RS11765	COG1414	Transcriptional regulator
C6N17_RS11775	COG0583	DNA-binding transcription factor activity
C6N17_RS11790	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS11815	COG0583	DNA-binding transcription factor activity
C6N17_RS11820	COG2050	protein possibly involved in aromatic compounds catabolism
C6N17_RS11845	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6N17_RS11850	COG0183	Belongs to the thiolase family
C6N17_RS11855	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N17_RS11860	COG1024	Enoyl-CoA hydratase
C6N17_RS11865	COG1024	Enoyl-CoA hydratase
C6N17_RS11870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N17_RS11875	COG2151	metal-sulfur cluster biosynthetic enzyme
C6N17_RS11880	COG3396	Phenylacetate-CoA oxygenase
C6N17_RS11885	COG3460	Phenylacetate-CoA oxygenase
C6N17_RS11890	COG3396	Phenylacetate-CoA oxygenase
C6N17_RS11895	COG2030	dehydratase
C6N17_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS11900	COG1760	l-serine dehydratase
C6N17_RS11920	COG0789	Transcriptional regulator
C6N17_RS11930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6N17_RS11935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS11950	COG2807	transmembrane transport
C6N17_RS11955	COG0590	tRNA wobble adenosine to inosine editing
C6N17_RS11960	COG0666	response to abiotic stimulus
C6N17_RS11985	COG4770	biotin carboxylase activity
C6N17_RS12000	COG1063	alcohol dehydrogenase
C6N17_RS12005	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N17_RS12040	COG3210	domain, Protein
C6N17_RS12050	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS12060	COG0038	chloride channel
C6N17_RS12065	COG4770	biotin carboxylase activity
C6N17_RS12085	COG1914	H( )-stimulated, divalent metal cation uptake system
C6N17_RS12100	COG1595	DNA-templated transcription, initiation
C6N17_RS12110	COG3220	belongs to the UPF0276 family
C6N17_RS12165	COG0531	amino acid
C6N17_RS12170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N17_RS12185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N17_RS12200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6N17_RS12210	COG4122	O-methyltransferase activity
C6N17_RS12240	COG1538	Outer membrane efflux protein
C6N17_RS12245	COG1137	ATPase activity
C6N17_RS12250	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6N17_RS12260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6N17_RS12355	COG1598	PFAM Uncharacterised protein family UPF0150
C6N17_RS12445	COG5410	chromosome segregation
C6N17_RS12640	COG2814	Major facilitator Superfamily
C6N17_RS12650	COG0668	transmembrane transport
C6N17_RS12695	COG1309	transcriptional regulator
C6N17_RS12705	COG2226	methyltransferase
C6N17_RS12710	COG1011	Hydrolase
C6N17_RS12730	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS12745	COG1278	Cold shock
C6N17_RS12750	COG1560	Kdo2-lipid A biosynthetic process
C6N17_RS12755	COG1280	lysine exporter protein (LysE YggA)
C6N17_RS12790	COG1570	exodeoxyribonuclease VII activity
C6N17_RS12870	COG2871	sodium ion transport
C6N17_RS12880	COG0583	DNA-binding transcription factor activity
C6N17_RS12890	COG4638	Rieske (2fe-2S)
C6N17_RS12895	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6N17_RS12900	COG0633	Ferredoxin
C6N17_RS12900	COG0543	2 iron, 2 sulfur cluster binding
C6N17_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS12910	COG3135	benzoate transporter
C6N17_RS12915	COG2814	Major facilitator Superfamily
C6N17_RS12930	COG1643	Atp-dependent helicase
C6N17_RS12955	COG3634	alkyl hydroperoxide reductase activity
C6N17_RS12975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C6N17_RS12980	COG0625	glutathione transferase activity
C6N17_RS12990	COG2885	chlorophyll binding
C6N17_RS13030	COG0542	response to heat
C6N17_RS13045	COG1765	OsmC-like protein
C6N17_RS13060	COG0667	Aldo Keto reductase
C6N17_RS13075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C6N17_RS13085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6N17_RS13095	COG0582	viral genome integration into host DNA
C6N17_RS13115	COG3293	Transposase
C6N17_RS13120	COG1063	alcohol dehydrogenase
C6N17_RS13155	COG1598	PFAM Uncharacterised protein family UPF0150
C6N17_RS13340	COG0527	aspartate kinase activity
C6N17_RS13350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C6N17_RS13360	COG3038	cytochrome b561
C6N17_RS13365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C6N17_RS13370	COG2252	PERMEase
C6N17_RS13380	COG1741	Belongs to the pirin family
C6N17_RS13385	COG1309	transcriptional regulator
C6N17_RS13400	COG2072	flavoprotein involved in K transport
C6N17_RS13405	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C6N17_RS13410	COG0583	DNA-binding transcription factor activity
C6N17_RS13425	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N17_RS13455	COG1944	ATP diphosphatase activity
C6N17_RS13475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6N17_RS13490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N17_RS13510	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6N17_RS13515	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS13530	COG2814	Major facilitator Superfamily
C6N17_RS13535	COG1024	Enoyl-CoA hydratase
C6N17_RS13550	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS13575	COG2186	Transcriptional regulator
C6N17_RS13580	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS13590	COG4948	Mandelate Racemase Muconate Lactonizing
C6N17_RS13595	COG2271	Major facilitator Superfamily
C6N17_RS13600	COG2721	sulfolactate sulfo-lyase activity
C6N17_RS13605	COG0697	spore germination
C6N17_RS13625	COG1113	amino acid transport
C6N17_RS13630	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS13670	COG0531	amino acid
C6N17_RS13680	COG1113	amino acid transport
C6N17_RS13715	COG2801	Transposase and inactivated derivatives
C6N17_RS13730	COG4269	membrane
C6N17_RS13750	COG1902	pentaerythritol trinitrate reductase activity
C6N17_RS13750	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N17_RS13760	COG2203	Gaf domain
C6N17_RS13760	COG5001	Diguanylate cyclase
C6N17_RS13760	COG3706	GGDEF domain
C6N17_RS13760	COG4251	negative regulation of phosphorylation
C6N17_RS13770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N17_RS13795	COG4172	Belongs to the ABC transporter superfamily
C6N17_RS13800	COG4239	(ABC) transporter, permease
C6N17_RS13805	COG4174	ABC transporter (Permease)
C6N17_RS13810	COG4166	transmembrane transport
C6N17_RS13815	COG1388	LysM domain
C6N17_RS13815	COG0741	lytic transglycosylase activity
C6N17_RS13860	COG0583	DNA-binding transcription factor activity
C6N17_RS13865	COG1279	arginine transmembrane transporter activity
C6N17_RS13885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N17_RS13890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N17_RS13895	COG0006	proline dipeptidase activity
C6N17_RS13935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6N17_RS13950	COG3384	dioxygenase
C6N17_RS13960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6N17_RS13965	COG2878	Part of a membrane complex involved in electron transport
C6N17_RS13970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6N17_RS13995	COG0768	penicillin binding
C6N17_RS14000	COG0742	ribosomal rna small subunit methyltransferase
C6N17_RS14015	COG0830	nickel cation binding
C6N17_RS14025	COG0804	urea catabolic process
C6N17_RS14055	COG3015	lipoprotein NlpE involved in copper resistance
C6N17_RS14070	COG1253	flavin adenine dinucleotide binding
C6N17_RS14075	COG2851	Citrate transporter
C6N17_RS14125	COG1773	rubredoxin
C6N17_RS14130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N17_RS14135	COG2267	carboxylic ester hydrolase activity
C6N17_RS14140	COG0583	DNA-binding transcription factor activity
C6N17_RS14170	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6N17_RS14175	COG4181	ATPase activity
C6N17_RS14220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6N17_RS14240	COG0306	phosphate transporter
C6N17_RS14270	COG2223	nitrite transmembrane transporter activity
C6N17_RS14275	COG2207	Transcriptional regulator
C6N17_RS14280	COG2066	Belongs to the glutaminase family
C6N17_RS14285	COG0242	peptide deformylase activity
C6N17_RS14290	COG0477	Major facilitator Superfamily
C6N17_RS14300	COG0028	Belongs to the TPP enzyme family
C6N17_RS14315	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS14320	COG2267	carboxylic ester hydrolase activity
C6N17_RS14330	COG2271	Major facilitator Superfamily
C6N17_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS14365	COG1414	Transcriptional regulator
C6N17_RS14390	COG1215	transferase activity, transferring glycosyl groups
C6N17_RS14395	COG1649	PFAM Uncharacterised BCR, COG1649
C6N17_RS14395	COG0726	polysaccharide deacetylase
C6N17_RS14405	COG4681	YaeQ
C6N17_RS14415	COG0523	cobalamin synthesis protein
C6N17_RS14425	COG1607	acyl-coa hydrolase
C6N17_RS14435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N17_RS14440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N17_RS14445	COG1309	transcriptional regulator
C6N17_RS14470	COG2040	homocysteine
C6N17_RS14475	COG0531	amino acid
C6N17_RS14530	COG1595	DNA-templated transcription, initiation
C6N17_RS14540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N17_RS14545	COG0477	Major facilitator Superfamily
C6N17_RS14640	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS14655	COG0405	Gamma-glutamyltransferase
C6N17_RS14660	COG2814	Major facilitator Superfamily
C6N17_RS14670	COG2050	protein possibly involved in aromatic compounds catabolism
C6N17_RS14685	COG1090	epimerase
C6N17_RS14705	COG0420	3'-5' exonuclease activity
C6N17_RS14730	COG0735	belongs to the Fur family
C6N17_RS14735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N17_RS14740	COG2914	Belongs to the UPF0125 (RnfH) family
C6N17_RS14760	COG2826	transposase and inactivated derivatives, IS30 family
C6N17_RS14765	COG0121	glutamine amidotransferase
C6N17_RS14780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N17_RS14790	COG0210	DNA helicase
C6N17_RS14795	COG2885	chlorophyll binding
C6N17_RS14800	COG0204	Acyl-transferase
C6N17_RS14815	COG2894	cell division
C6N17_RS14835	COG1280	lysine exporter protein (LysE YggA)
C6N17_RS14840	COG1674	ftsk spoiiie
C6N17_RS14845	COG0492	ferredoxin-NADP+ reductase activity
C6N17_RS14850	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C6N17_RS14860	COG0456	acetyltransferase
C6N17_RS14875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C6N17_RS14880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C6N17_RS14890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C6N17_RS14905	COG1981	membrane
C6N17_RS14915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C6N17_RS14915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N17_RS14935	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS14940	COG4638	Rieske (2fe-2S)
C6N17_RS14945	COG0657	acetylesterase activity
C6N17_RS14955	COG0473	3-isopropylmalate dehydrogenase activity
C6N17_RS14960	COG0583	DNA-binding transcription factor activity
C6N17_RS14980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6N17_RS15015	COG0358	DNA primase activity
C6N17_RS15030	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C6N17_RS15060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N17_RS15090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6N17_RS15095	COG3328	transposase activity
C6N17_RS15105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6N17_RS15105	COG0352	thiamine-phosphate diphosphorylase activity
C6N17_RS15105	COG0351	phosphomethylpyrimidine kinase
C6N17_RS15110	COG1652	LysM domain
C6N17_RS15135	COG1399	metal-binding, possibly nucleic acid-binding protein
C6N17_RS15140	COG3101	peptidyl-lysine hydroxylation
C6N17_RS15145	COG0009	L-threonylcarbamoyladenylate synthase
C6N17_RS15150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C6N17_RS15155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C6N17_RS15170	COG4106	trans-aconitate 2-methyltransferase activity
C6N17_RS15185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N17_RS15185	COG2226	methyltransferase
C6N17_RS15185	COG0596	Alpha beta hydrolase
C6N17_RS15195	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C6N17_RS15200	COG2223	nitrite transmembrane transporter activity
C6N17_RS15220	COG1196	nuclear chromosome segregation
C6N17_RS15230	COG0730	response to heat
C6N17_RS15245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6N17_RS15255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N17_RS15305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6N17_RS15310	COG0489	protein tyrosine kinase activity
C6N17_RS15320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N17_RS15320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N17_RS15355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C6N17_RS15360	COG2081	HI0933 family
C6N17_RS15370	COG0668	transmembrane transport
C6N17_RS15390	COG0583	DNA-binding transcription factor activity
C6N17_RS15410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N17_RS15415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N17_RS15445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6N17_RS15470	COG2199	diguanylate cyclase activity
C6N17_RS15485	COG0745	RESPONSE REGULATOR receiver
C6N17_RS15500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N17_RS15575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N17_RS15590	COG0583	DNA-binding transcription factor activity
C6N17_RS15640	COG0583	DNA-binding transcription factor activity
C6N17_RS15660	COG0583	DNA-binding transcription factor activity
C6N17_RS15665	COG1053	succinate dehydrogenase
C6N17_RS15680	COG1309	transcriptional regulator
C6N17_RS15690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6N17_RS15695	COG2814	Major facilitator Superfamily
C6N17_RS15700	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS15705	COG0583	DNA-binding transcription factor activity
C6N17_RS15710	COG1063	alcohol dehydrogenase
C6N17_RS15745	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C6N17_RS15750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C6N17_RS15755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N17_RS15775	COG2132	Multicopper oxidase
C6N17_RS15785	COG0561	phosphatase activity
C6N17_RS15790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6N17_RS15815	COG1214	PFAM Peptidase M22, glycoprotease
C6N17_RS15875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6N17_RS15880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C6N17_RS15885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C6N17_RS15945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N17_RS15955	COG1846	Transcriptional regulator
C6N17_RS15960	COG1764	response to oxidative stress
C6N17_RS16000	COG0037	tRNA processing
C6N17_RS16010	COG0248	Ppx GppA phosphatase
C6N17_RS16040	COG0072	phenylalanine-tRNA ligase activity
C6N17_RS16070	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C6N17_RS16085	COG1238	metal cluster binding
C6N17_RS16090	COG0625	glutathione transferase activity
C6N17_RS16110	COG0318	PFAM AMP-dependent synthetase and ligase
C6N17_RS16115	COG3028	Belongs to the UPF0307 family
C6N17_RS16120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N17_RS16140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6N17_RS16145	COG0617	tRNA 3'-terminal CCA addition
C6N17_RS16150	COG1555	photosystem II stabilization
C6N17_RS16155	COG3956	TIGRFAM MazG family protein
C6N17_RS16160	COG4221	oxidoreductase activity
C6N17_RS16165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N17_RS16180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N17_RS16185	COG5002	protein histidine kinase activity
C6N17_RS16185	COG2205	protein histidine kinase activity
C6N17_RS16185	COG0784	Response regulator, receiver
C6N17_RS16190	COG1024	Enoyl-CoA hydratase
C6N17_RS16195	COG2084	Dehydrogenase
C6N17_RS16200	COG3622	Belongs to the hyi family
C6N17_RS16230	COG0697	spore germination
C6N17_RS16240	COG2814	Major facilitator Superfamily
C6N17_RS16275	COG2072	flavoprotein involved in K transport
C6N17_RS16280	COG0492	ferredoxin-NADP+ reductase activity
C6N17_RS16285	COG0431	NADPH-dependent FMN reductase
C6N17_RS16290	COG0798	PFAM Bile acid sodium symporter
C6N17_RS16300	COG0640	Transcriptional regulator
C6N17_RS16340	COG2205	protein histidine kinase activity
C6N17_RS16425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N17_RS16440	COG0583	DNA-binding transcription factor activity
C6N17_RS16450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6N17_RS16460	COG0084	hydrolase, TatD family'
C6N17_RS16475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C6N17_RS16505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C6N17_RS16510	COG0440	acetolactate synthase activity
C6N17_RS16515	COG0028	Belongs to the TPP enzyme family
C6N17_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6N17_RS16540	COG0577	efflux transmembrane transporter activity
C6N17_RS16540	COG1136	(ABC) transporter
C6N17_RS16570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C6N17_RS16575	COG1162	GTPase activity
C6N17_RS16585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6N17_RS16605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6N17_RS16625	COG1426	Protein conserved in bacteria
C6N17_RS16660	COG0793	Belongs to the peptidase S41A family
C6N17_RS16675	COG2267	carboxylic ester hydrolase activity
C6N17_RS16685	COG1012	belongs to the aldehyde dehydrogenase family
C6N17_RS16690	COG3265	gluconokinase activity
C6N17_RS16700	COG0800	Aldolase
C6N17_RS16715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N17_RS16720	COG0280	phosphate acetyltransferase
C6N17_RS16720	COG0857	belongs to the CobB CobQ family
C6N17_RS16725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N17_RS16725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6N17_RS16745	COG0740	serine-type endopeptidase activity
C6N17_RS16755	COG4774	siderophore transport
C6N17_RS16765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C6N17_RS16775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N17_RS16775	COG2813	Specifically methylates the guanine in position
C6N17_RS16875	COG0788	formyltetrahydrofolate deformylase activity
C6N17_RS16900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N17_RS16900	COG4651	solute:proton antiporter activity
C6N17_RS16920	COG0724	RNA recognition motif
C6N17_RS16925	COG0210	DNA helicase
C6N17_RS16950	COG1733	regulation of RNA biosynthetic process
C6N17_RS16960	COG2900	Belongs to the SlyX family
C6N17_RS16965	COG0488	(ABC) transporter
C6N17_RS16975	COG1560	Kdo2-lipid A biosynthetic process
C6N17_RS16985	COG1301	dicarboxylic acid transport
C6N17_RS17040	COG0473	3-isopropylmalate dehydrogenase activity
C6N17_RS17065	COG0583	DNA-binding transcription factor activity
C6N17_RS17105	COG0583	DNA-binding transcription factor activity
C6N17_RS17115	COG0625	glutathione transferase activity
C6N17_RS17120	COG2378	regulation of single-species biofilm formation
C6N17_RS17125	COG0546	phosphoglycolate phosphatase activity
C6N17_RS17140	COG1530	ribonuclease E activity
C6N17_RS17145	COG0318	PFAM AMP-dependent synthetase and ligase
C6N17_RS17160	COG0583	DNA-binding transcription factor activity
C6N17_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS17170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6N17_RS17180	COG0534	Mate efflux family protein
C6N17_RS17195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6N17_RS17220	COG0493	'glutamate synthase
C6N17_RS17230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C6N17_RS17235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N17_RS17250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6N17_RS17260	COG0644	oxidoreductase
C6N17_RS17260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6N17_RS17275	COG4535	Mg2 and Co2 transporter CorC
C6N17_RS17285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N17_RS17305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6N17_RS17315	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C6N17_RS17325	COG0484	heat shock protein binding
C6N17_RS17330	COG0789	Transcriptional regulator
C6N17_RS17335	COG0598	Magnesium transport protein CorA
C6N17_RS17340	COG1185	polyribonucleotide nucleotidyltransferase activity
C6N17_RS17350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N17_RS17355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N17_RS17360	COG1074	ATP-dependent DNA helicase activity
C6N17_RS17365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6N17_RS17385	COG2226	methyltransferase
C6N17_RS17400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N17_RS17410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C6N17_RS17425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N17_RS17425	COG2111	Na H antiporter
C6N17_RS17430	COG1006	Multisubunit Na H antiporter MnhC subunit
C6N17_RS17435	COG0651	ATP synthesis coupled electron transport
C6N17_RS17440	COG1863	multisubunit Na H antiporter MnhE subunit
C6N17_RS17445	COG2212	antiporter activity
C6N17_RS17450	COG1320	monovalent cation:proton antiporter activity
C6N17_RS17455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C6N17_RS17465	COG0195	Participates in both transcription termination and antitermination
C6N17_RS17515	COG0237	dephospho-CoA kinase activity
C6N17_RS17525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N17_RS17540	COG0497	DNA recombination
C6N17_RS17550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C6N17_RS17585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N17_RS17585	COG2169	Transcriptional regulator
C6N17_RS17590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6N17_RS17660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C6N17_RS17675	COG0326	Molecular chaperone. Has ATPase activity
C6N17_RS17690	COG2056	Na+-H+ antiporter family
C6N17_RS17760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C6N17_RS17790	COG0546	phosphoglycolate phosphatase activity
C6N17_RS17795	COG1716	ATPase activity
C6N17_RS17845	COG0181	hydroxymethylbilane synthase activity
C6N17_RS17855	COG3275	phosphorelay sensor kinase activity
C6N17_RS17875	COG1538	Outer membrane efflux protein
C6N17_RS17885	COG0697	spore germination
C6N17_RS17905	COG0494	nUDIX hydrolase
C6N17_RS17910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6N17_RS17915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6N17_RS17920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6N17_RS17925	COG0772	Belongs to the SEDS family
C6N17_RS17950	COG4974	Belongs to the 'phage' integrase family
C6N17_RS17955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N17_RS17965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6N17_RS17975	COG2197	response regulator
C6N17_RS17990	COG0793	Belongs to the peptidase S41A family
C6N17_RS17995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C6N17_RS18000	COG0795	lipopolysaccharide-transporting ATPase activity
C6N17_RS18040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N17_RS18040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N17_RS18050	COG0004	ammonium transporteR
C6N17_RS18055	COG0347	Belongs to the P(II) protein family
C6N17_RS18065	COG0606	chelatase, subunit chli
C6N17_RS18070	COG0431	NADPH-dependent FMN reductase
C6N17_RS18075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS18080	COG0235	Class ii aldolase
C6N17_RS18085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N17_RS18105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6N17_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
C6N17_RS18130	COG0477	Major facilitator Superfamily
C6N17_RS18135	COG2860	membrane
C6N17_RS18145	COG1253	flavin adenine dinucleotide binding
C6N17_RS18155	COG2814	Major facilitator Superfamily
C6N17_RS18165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N17_RS18205	COG0655	NAD(P)H dehydrogenase (quinone) activity
C6N17_RS18220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N17_RS18250	COG1309	transcriptional regulator
C6N17_RS18285	COG0758	DNA mediated transformation
C6N17_RS18295	COG0697	spore germination
C6N17_RS18300	COG1309	transcriptional regulator
C6N17_RS18315	COG0386	Belongs to the glutathione peroxidase family
C6N17_RS18330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C6N17_RS18340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C6N17_RS18380	COG1121	(ABC) transporter
C6N17_RS18385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N17_RS18390	COG1280	lysine exporter protein (LysE YggA)
C6N17_RS18395	COG2837	iron assimilation
C6N17_RS18400	COG0281	malic enzyme
C6N17_RS18450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6N17_RS18450	COG0519	Catalyzes the synthesis of GMP from XMP
C6N17_RS18455	COG4399	Belongs to the UPF0754 family
C6N17_RS18460	COG2259	Doxx family
C6N17_RS18465	COG0586	Pfam SNARE associated Golgi protein
C6N17_RS18480	COG1192	Involved in chromosome partitioning
C6N17_RS18490	COG0271	Belongs to the BolA IbaG family
C6N17_RS18515	COG3328	transposase activity
C6N17_RS18540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6N17_RS18540	COG3321	synthase
C6N17_RS18540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N17_RS18540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6N17_RS18545	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS18550	COG0318	PFAM AMP-dependent synthetase and ligase
C6N17_RS18555	COG2197	response regulator
C6N17_RS18565	COG3916	Acyl-homoserine-lactone synthase
C6N17_RS18570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N17_RS18580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N17_RS18585	COG1113	amino acid transport
C6N17_RS18590	COG0697	spore germination
C6N17_RS18595	COG0477	Major facilitator Superfamily
C6N17_RS18600	COG1024	Enoyl-CoA hydratase
C6N17_RS18605	COG1024	Enoyl-CoA hydratase
C6N17_RS18610	COG1960	acyl-CoA dehydrogenase activity
C6N17_RS18615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N17_RS18635	COG1113	amino acid transport
C6N17_RS18640	COG1113	amino acid transport
C6N17_RS18645	COG0251	oxidation-reduction process
C6N17_RS18685	COG0564	pseudouridine synthase activity
C6N17_RS18760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6N17_RS18775	COG1802	Transcriptional regulator
C6N17_RS18780	COG1448	Aminotransferase
C6N17_RS18785	COG0277	FAD linked oxidase domain protein
C6N17_RS18795	COG2186	Transcriptional regulator
C6N17_RS18805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N17_RS18825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6N17_RS18830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6N17_RS18855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N17_RS18860	COG2244	polysaccharide biosynthetic process
C6N17_RS18870	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6N17_RS18875	COG1091	dTDP-4-dehydrorhamnose reductase activity
C6N17_RS18885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6N17_RS18890	COG1596	polysaccharide export
C6N17_RS18915	COG0728	peptidoglycan biosynthetic process
C6N17_RS18920	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6N17_RS18975	COG0546	phosphoglycolate phosphatase activity
C6N17_RS18980	COG1028	Short-chain dehydrogenase reductase Sdr
C6N17_RS18995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6N17_RS18995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6N17_RS19000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N17_RS19005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N17_RS19010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N17_RS19015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N17_RS19020	COG1116	anion transmembrane transporter activity
C6N17_RS19025	COG1309	transcriptional regulator
C6N17_RS19030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6N17_RS19040	COG0196	riboflavin kinase activity
C6N17_RS19045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C6N17_RS19055	COG1047	Peptidyl-prolyl cis-trans
C6N17_RS19065	COG3328	transposase activity
C6N17_RS19100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N17_RS19105	COG0657	acetylesterase activity
C6N17_RS19155	COG2951	lytic endotransglycosylase activity
C6N17_RS19160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6N17_RS19175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6N17_RS19185	COG0671	phosphoesterase, PA-phosphatase related
C6N17_RS19190	COG0861	Integral membrane protein TerC family
C6N17_RS19200	COG0754	glutathionylspermidine amidase activity
C6N17_RS19210	COG0402	S-adenosylhomocysteine deaminase activity
C6N17_RS19225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N17_RS19230	COG1230	cation diffusion facilitator family transporter
C6N17_RS19245	COG0706	membrane insertase activity