locus-tag	class	description
H7R23_RS00010	COG0592	DNA-directed DNA polymerase activity
H7R23_RS00020	COG0187	DNA topoisomerase II activity
H7R23_RS00035	COG0488	(ABC) transporter
H7R23_RS00060	COG0596	Alpha beta hydrolase
H7R23_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H7R23_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7R23_RS00100	COG0625	glutathione transferase activity
H7R23_RS00110	COG0733	neurotransmitter:sodium symporter activity
H7R23_RS00150	COG2233	PERMEase
H7R23_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS00200	COG2814	Major facilitator Superfamily
H7R23_RS00205	COG0656	L-ascorbic acid biosynthetic process
H7R23_RS00210	COG0583	DNA-binding transcription factor activity
H7R23_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R23_RS00230	COG1064	alcohol dehydrogenase
H7R23_RS00235	COG2818	Glycosylase
H7R23_RS00250	COG1194	a g-specific adenine glycosylase
H7R23_RS00265	COG5487	UPF0391 membrane protein
H7R23_RS00270	COG2983	Belongs to the UPF0260 family
H7R23_RS00275	COG2133	pyrroloquinoline quinone binding
H7R23_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7R23_RS00285	COG2116	formate transmembrane transporter activity
H7R23_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R23_RS00310	COG1335	isochorismatase
H7R23_RS00315	COG0385	Bile acid
H7R23_RS00320	COG0534	Mate efflux family protein
H7R23_RS00325	COG1683	Conserved Protein
H7R23_RS00340	COG0346	lactoylglutathione lyase activity
H7R23_RS00345	COG0625	glutathione transferase activity
H7R23_RS00355	COG1113	amino acid transport
H7R23_RS00365	COG0523	cobalamin synthesis protein
H7R23_RS00375	COG2188	Transcriptional regulator
H7R23_RS00405	COG0010	Belongs to the arginase family
H7R23_RS00420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R23_RS00470	COG0546	phosphoglycolate phosphatase activity
H7R23_RS00475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7R23_RS00485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7R23_RS00495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7R23_RS00500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7R23_RS00600	COG0534	Mate efflux family protein
H7R23_RS00605	COG0436	Aminotransferase
H7R23_RS00610	COG2733	membrane
H7R23_RS00625	COG2918	glutathione biosynthetic process
H7R23_RS00670	COG3150	esterase
H7R23_RS00680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H7R23_RS00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R23_RS00700	COG2233	PERMEase
H7R23_RS00705	COG2351	hydroxyisourate hydrolase activity
H7R23_RS00740	COG3706	GGDEF domain
H7R23_RS00755	COG1393	Belongs to the ArsC family
H7R23_RS00760	COG0708	Exodeoxyribonuclease III
H7R23_RS00790	COG0189	ligase activity
H7R23_RS00810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7R23_RS00820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7R23_RS00835	COG4942	peptidase
H7R23_RS00845	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R23_RS00855	COG2119	membrane
H7R23_RS00860	COG4774	siderophore transport
H7R23_RS00865	COG0426	domain, Protein
H7R23_RS00865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R23_RS00885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7R23_RS00905	COG1902	pentaerythritol trinitrate reductase activity
H7R23_RS00910	COG1519	Transferase
H7R23_RS00915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7R23_RS00920	COG0668	transmembrane transport
H7R23_RS00930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R23_RS00935	COG1335	isochorismatase
H7R23_RS00940	COG1522	sequence-specific DNA binding
H7R23_RS00965	COG0784	Response regulator, receiver
H7R23_RS00965	COG2198	Histidine kinase
H7R23_RS00965	COG2205	protein histidine kinase activity
H7R23_RS00970	COG3162	membrane
H7R23_RS00975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R23_RS00985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R23_RS01005	COG1309	transcriptional regulator
H7R23_RS01025	COG0300	oxidoreductase activity
H7R23_RS01035	COG0351	phosphomethylpyrimidine kinase
H7R23_RS01035	COG0352	thiamine-phosphate diphosphorylase activity
H7R23_RS01035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7R23_RS01045	COG2814	Major facilitator Superfamily
H7R23_RS01060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7R23_RS01070	COG1113	amino acid transport
H7R23_RS01080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R23_RS01085	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS01095	COG1335	isochorismatase
H7R23_RS01190	COG1309	transcriptional regulator
H7R23_RS01210	COG2814	Major facilitator Superfamily
H7R23_RS01215	COG0583	DNA-binding transcription factor activity
H7R23_RS01235	COG0667	Aldo Keto reductase
H7R23_RS01270	COG1733	regulation of RNA biosynthetic process
H7R23_RS01275	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R23_RS01345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7R23_RS01360	COG2329	Antibiotic biosynthesis monooxygenase
H7R23_RS01375	COG1132	(ABC) transporter
H7R23_RS01395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7R23_RS01425	COG0427	acetyl-CoA hydrolase
H7R23_RS01450	COG0659	secondary active sulfate transmembrane transporter activity
H7R23_RS01455	COG4221	oxidoreductase activity
H7R23_RS01460	COG2873	o-acetylhomoserine
H7R23_RS01465	COG0488	(ABC) transporter
H7R23_RS01545	COG0833	amino acid
H7R23_RS01590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7R23_RS01595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7R23_RS01610	COG2226	methyltransferase
H7R23_RS01660	COG0067	glutamate synthase
H7R23_RS01660	COG0069	glutamate synthase activity
H7R23_RS01660	COG0070	glutamate synthase
H7R23_RS01665	COG0493	'glutamate synthase
H7R23_RS01675	COG1704	LemA family
H7R23_RS01680	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7R23_RS01700	COG3307	-O-antigen
H7R23_RS01725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R23_RS01740	COG0194	GDP metabolic process
H7R23_RS01790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7R23_RS01800	COG0335	large ribosomal subunit rRNA binding
H7R23_RS01810	COG5380	lipid catabolic process
H7R23_RS01815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7R23_RS01830	COG5006	permease, DMT superfamily
H7R23_RS01835	COG5006	permease, DMT superfamily
H7R23_RS01840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R23_RS01845	COG0277	FAD linked oxidase domain protein
H7R23_RS01855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7R23_RS01860	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R23_RS01875	COG1289	transmembrane transporter activity
H7R23_RS01885	COG0628	permease
H7R23_RS01890	COG1192	Involved in chromosome partitioning
H7R23_RS01920	COG0833	amino acid
H7R23_RS01925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R23_RS01930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R23_RS01940	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS01980	COG0583	DNA-binding transcription factor activity
H7R23_RS02005	COG0752	glycyl-tRNA synthetase alpha subunit
H7R23_RS02035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7R23_RS02035	COG0617	tRNA 3'-terminal CCA addition
H7R23_RS02035	COG0517	IMP dehydrogenase activity
H7R23_RS02040	COG1983	PspC domain protein
H7R23_RS02050	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS02065	COG0408	coproporphyrinogen oxidase activity
H7R23_RS02085	COG0513	Belongs to the DEAD box helicase family
H7R23_RS02095	COG1127	ABC transporter
H7R23_RS02100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7R23_RS02110	COG2854	intermembrane phospholipid transfer
H7R23_RS02120	COG0598	Magnesium transport protein CorA
H7R23_RS02130	COG0494	nUDIX hydrolase
H7R23_RS02135	COG1040	competence protein
H7R23_RS02140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7R23_RS02160	COG1946	Acyl-CoA thioesterase
H7R23_RS02165	COG1301	dicarboxylic acid transport
H7R23_RS02180	COG1959	2 iron, 2 sulfur cluster binding
H7R23_RS02185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R23_RS02185	COG1017	nitric oxide dioxygenase activity
H7R23_RS02195	COG0433	COG0433 Predicted ATPase
H7R23_RS02200	COG0626	cystathionine gamma-synthase activity
H7R23_RS02215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7R23_RS02220	COG0088	Forms part of the polypeptide exit tunnel
H7R23_RS02355	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS02360	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7R23_RS02390	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H7R23_RS02395	COG0339	signal peptide processing
H7R23_RS02400	COG0557	exoribonuclease II activity
H7R23_RS02460	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7R23_RS02465	COG1295	ribonuclease BN
H7R23_RS02500	COG1702	phosphate starvation-inducible protein PhoH
H7R23_RS02510	COG0739	heme binding
H7R23_RS02510	COG0741	lytic transglycosylase activity
H7R23_RS02510	COG1196	nuclear chromosome segregation
H7R23_RS02540	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7R23_RS02545	COG1183	phosphatidylcholine synthase activity
H7R23_RS02590	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS02595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R23_RS02600	COG1309	transcriptional regulator
H7R23_RS02615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7R23_RS02620	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS02660	COG2969	positive regulation of protein catabolic process
H7R23_RS02665	COG0625	glutathione transferase activity
H7R23_RS02670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7R23_RS02675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7R23_RS02680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7R23_RS02685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7R23_RS02690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7R23_RS02710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7R23_RS02720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R23_RS02725	COG1408	metallophosphoesterase
H7R23_RS02730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H7R23_RS02730	COG2885	chlorophyll binding
H7R23_RS02735	COG2199	diguanylate cyclase activity
H7R23_RS02805	COG1607	acyl-coa hydrolase
H7R23_RS02840	COG2350	Protein conserved in bacteria
H7R23_RS02855	COG3781	membrane
H7R23_RS02865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7R23_RS02870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R23_RS02880	COG1862	Preprotein translocase
H7R23_RS02905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H7R23_RS02920	COG0726	polysaccharide deacetylase
H7R23_RS02935	COG1216	Glycosyl transferase, family 2
H7R23_RS02985	COG0625	glutathione transferase activity
H7R23_RS02990	COG0583	DNA-binding transcription factor activity
H7R23_RS02995	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS03000	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS03010	COG2205	protein histidine kinase activity
H7R23_RS03015	COG0745	RESPONSE REGULATOR receiver
H7R23_RS03025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H7R23_RS03045	COG2096	Adenosyltransferase
H7R23_RS03050	COG4206	TonB-dependent receptor
H7R23_RS03095	COG0285	dihydrofolate synthase activity
H7R23_RS03115	COG0450	alkyl hydroperoxide reductase
H7R23_RS03130	COG0477	Major facilitator Superfamily
H7R23_RS03135	COG1272	protein, Hemolysin III
H7R23_RS03145	COG2153	protein acetylation
H7R23_RS03165	COG0183	Belongs to the thiolase family
H7R23_RS03170	COG2207	Transcriptional regulator
H7R23_RS03190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R23_RS03210	COG0183	Belongs to the thiolase family
H7R23_RS03220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H7R23_RS03220	COG2885	chlorophyll binding
H7R23_RS03230	COG1690	Belongs to the RtcB family
H7R23_RS03235	COG0833	amino acid
H7R23_RS03245	COG2233	PERMEase
H7R23_RS03250	COG1217	gtp-binding protein TYPA
H7R23_RS03275	COG2094	Belongs to the DNA glycosylase MPG family
H7R23_RS03280	COG4772	TonB-dependent receptor
H7R23_RS03285	COG1902	pentaerythritol trinitrate reductase activity
H7R23_RS03300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R23_RS03305	COG0354	folic acid binding
H7R23_RS03325	COG2233	PERMEase
H7R23_RS03330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R23_RS03335	COG0251	oxidation-reduction process
H7R23_RS03340	COG1335	isochorismatase
H7R23_RS03345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R23_RS03355	COG0596	Alpha beta hydrolase
H7R23_RS03360	COG3189	MarR family transcriptional regulator
H7R23_RS03365	COG2824	Alkylphosphonate utilization operon protein PhnA
H7R23_RS03370	COG3422	double-strand break repair
H7R23_RS03410	COG0840	transmembrane signaling receptor activity
H7R23_RS03435	COG5510	response to toxic substance
H7R23_RS03445	COG2832	Protein of unknown function (DUF454)
H7R23_RS03450	COG1376	ErfK ybiS ycfS ynhG family protein
H7R23_RS03490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7R23_RS03500	COG1289	transmembrane transporter activity
H7R23_RS03505	COG2814	Major facilitator Superfamily
H7R23_RS03525	COG1115	amino acid carrier protein
H7R23_RS03530	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R23_RS03535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7R23_RS03540	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H7R23_RS03545	COG3590	peptidase
H7R23_RS03570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7R23_RS03580	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7R23_RS03585	COG1077	Cell shape determining protein MreB Mrl
H7R23_RS03590	COG1792	Involved in formation and maintenance of cell shape
H7R23_RS03595	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7R23_RS03600	COG0424	maF-like protein
H7R23_RS03605	COG1530	ribonuclease E activity
H7R23_RS03615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R23_RS03635	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R23_RS03660	COG2207	Transcriptional regulator
H7R23_RS03680	COG0464	growth
H7R23_RS03730	COG0305	Participates in initiation and elongation during chromosome replication
H7R23_RS03765	COG0582	viral genome integration into host DNA
H7R23_RS03785	COG3046	protein related to deoxyribodipyrimidine photolyase
H7R23_RS03795	COG1113	amino acid transport
H7R23_RS03800	COG2828	Protein conserved in bacteria
H7R23_RS03805	COG0142	geranyltranstransferase activity
H7R23_RS03810	COG2315	Protein conserved in bacteria
H7R23_RS03825	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R23_RS03850	COG2194	sulfuric ester hydrolase activity
H7R23_RS03855	COG0745	RESPONSE REGULATOR receiver
H7R23_RS03860	COG0642	Histidine kinase
H7R23_RS03870	COG0004	ammonium transporteR
H7R23_RS03875	COG0583	DNA-binding transcription factor activity
H7R23_RS03900	COG0525	valine-tRNA ligase activity
H7R23_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS03920	COG0393	Putative heavy-metal-binding
H7R23_RS03925	COG0393	Putative heavy-metal-binding
H7R23_RS03930	COG1538	Outer membrane efflux protein
H7R23_RS03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS03945	COG0671	phosphoesterase, PA-phosphatase related
H7R23_RS03970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7R23_RS03985	COG1648	precorrin-2 dehydrogenase activity
H7R23_RS03985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7R23_RS03990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7R23_RS04025	COG0531	amino acid
H7R23_RS04040	COG0321	lipoyl(octanoyl) transferase activity
H7R23_RS04045	COG2921	Belongs to the UPF0250 family
H7R23_RS04085	COG2009	succinate dehydrogenase
H7R23_RS04090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H7R23_RS04095	COG1053	succinate dehydrogenase
H7R23_RS04100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7R23_RS04125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R23_RS04145	COG2354	Protein conserved in bacteria
H7R23_RS04150	COG2321	neutral zinc metallopeptidase
H7R23_RS04205	COG2843	Capsule synthesis protein
H7R23_RS04225	COG0589	response to stress
H7R23_RS04235	COG0251	oxidation-reduction process
H7R23_RS04240	COG1309	transcriptional regulator
H7R23_RS04255	COG0505	Belongs to the CarA family
H7R23_RS04285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R23_RS04290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7R23_RS04340	COG0477	Major facilitator Superfamily
H7R23_RS04345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7R23_RS04360	COG1597	lipid kinase activity
H7R23_RS04365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7R23_RS04395	COG0584	glycerophosphoryl diester phosphodiesterase
H7R23_RS04415	COG0741	lytic transglycosylase activity
H7R23_RS04435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7R23_RS04440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7R23_RS04475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS04480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R23_RS04485	COG0778	Nitroreductase
H7R23_RS04500	COG1929	Belongs to the glycerate kinase type-1 family
H7R23_RS04505	COG0243	molybdopterin cofactor binding
H7R23_RS04510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7R23_RS04540	COG1115	amino acid carrier protein
H7R23_RS04545	COG1113	amino acid transport
H7R23_RS04555	COG0019	diaminopimelate decarboxylase activity
H7R23_RS04565	COG2267	carboxylic ester hydrolase activity
H7R23_RS04570	COG1280	lysine exporter protein (LysE YggA)
H7R23_RS04575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7R23_RS04605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS04640	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7R23_RS04645	COG1136	(ABC) transporter
H7R23_RS04650	COG0658	competence protein
H7R23_RS04650	COG2333	competence protein COMEC
H7R23_RS04660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H7R23_RS04660	COG0616	signal peptide processing
H7R23_RS04665	COG0596	Alpha beta hydrolase
H7R23_RS04670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7R23_RS04680	COG0628	permease
H7R23_RS04715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R23_RS04735	COG0823	Involved in the tonB-independent uptake of proteins
H7R23_RS04755	COG0824	Thioesterase
H7R23_RS04760	COG1473	amidohydrolase
H7R23_RS04780	COG0047	phosphoribosylformylglycinamidine synthase activity
H7R23_RS04780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7R23_RS04785	COG2814	Major facilitator Superfamily
H7R23_RS04795	COG1024	Enoyl-CoA hydratase
H7R23_RS04800	COG1056	cytidyltransferase-related domain
H7R23_RS04800	COG1051	belongs to the nudix hydrolase family
H7R23_RS04815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7R23_RS04830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7R23_RS04845	COG4625	pathogenesis
H7R23_RS04850	COG0583	DNA-binding transcription factor activity
H7R23_RS04855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7R23_RS04860	COG4208	sulfate ABC transporter
H7R23_RS04865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H7R23_RS04875	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7R23_RS04880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7R23_RS04885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7R23_RS04905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R23_RS04920	COG0481	GTPase activity
H7R23_RS04925	COG0681	Belongs to the peptidase S26 family
H7R23_RS04935	COG0571	ribonuclease III activity
H7R23_RS04940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7R23_RS04955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7R23_RS04965	COG4221	oxidoreductase activity
H7R23_RS04995	COG0436	Aminotransferase
H7R23_RS05015	COG0556	nucleotide-excision repair
H7R23_RS05025	COG2962	Rard protein
H7R23_RS05070	COG2070	2-Nitropropane dioxygenase
H7R23_RS05085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7R23_RS05100	COG1215	transferase activity, transferring glycosyl groups
H7R23_RS05115	COG0415	Belongs to the DNA photolyase family
H7R23_RS05125	COG1252	NADH dehydrogenase
H7R23_RS05130	COG1686	Belongs to the peptidase S11 family
H7R23_RS05145	COG1187	pseudouridine synthase activity
H7R23_RS05155	COG0477	Major facilitator Superfamily
H7R23_RS05160	COG0583	DNA-binding transcription factor activity
H7R23_RS05165	COG1823	symporter activity
H7R23_RS05175	COG0612	Peptidase, M16
H7R23_RS05200	COG0352	thiamine-phosphate diphosphorylase activity
H7R23_RS05235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R23_RS05250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R23_RS05255	COG0076	glutamate decarboxylase activity
H7R23_RS05265	COG1522	sequence-specific DNA binding
H7R23_RS05270	COG3961	Belongs to the TPP enzyme family
H7R23_RS05275	COG1113	amino acid transport
H7R23_RS05280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7R23_RS05285	COG0573	inorganic phosphate transmembrane transporter activity
H7R23_RS05295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7R23_RS05300	COG0616	signal peptide processing
H7R23_RS05335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7R23_RS05340	COG1686	Belongs to the peptidase S11 family
H7R23_RS05365	COG0583	DNA-binding transcription factor activity
H7R23_RS05370	COG1067	ATP-dependent peptidase activity
H7R23_RS05375	COG2211	Major facilitator Superfamily
H7R23_RS05410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7R23_RS05415	COG1966	Carbon starvation protein
H7R23_RS05420	COG2879	small protein
H7R23_RS05445	COG1301	dicarboxylic acid transport
H7R23_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS05480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R23_RS05485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R23_RS05490	COG0183	Belongs to the thiolase family
H7R23_RS05495	COG4829	muconolactone delta-isomerase
H7R23_RS05525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7R23_RS05530	COG1741	Belongs to the pirin family
H7R23_RS05545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R23_RS05550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R23_RS05555	COG4605	iron ion homeostasis
H7R23_RS05560	COG4604	ABC transporter, ATP-binding protein
H7R23_RS05565	COG4607	ABC-type enterochelin transport system periplasmic component
H7R23_RS05570	COG4774	siderophore transport
H7R23_RS05580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R23_RS05585	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7R23_RS05590	COG3433	isochorismatase activity
H7R23_RS05590	COG1535	isochorismatase
H7R23_RS05605	COG1132	(ABC) transporter
H7R23_RS05610	COG1132	(ABC) transporter
H7R23_RS05615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7R23_RS05620	COG2977	Belongs to the P-Pant transferase superfamily
H7R23_RS05625	COG1169	isochorismate synthase
H7R23_RS05640	COG3739	integral membrane protein
H7R23_RS05660	COG0302	gtp cyclohydrolase
H7R23_RS05670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7R23_RS05680	COG2840	Smr protein MutS2
H7R23_RS05705	COG0512	Glutamine amidotransferase of anthranilate synthase
H7R23_RS05720	COG0174	glutamine synthetase
H7R23_RS05730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7R23_RS05765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7R23_RS05770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7R23_RS05775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R23_RS05795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7R23_RS05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7R23_RS05805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7R23_RS05820	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS05825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7R23_RS05830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R23_RS05840	COG2223	nitrite transmembrane transporter activity
H7R23_RS05850	COG0024	Methionine aminopeptidase
H7R23_RS05855	COG0052	Belongs to the universal ribosomal protein uS2 family
H7R23_RS05870	COG2207	Transcriptional regulator
H7R23_RS05895	COG2951	lytic endotransglycosylase activity
H7R23_RS05900	COG0772	Belongs to the SEDS family
H7R23_RS05915	COG0842	Transport permease protein
H7R23_RS05920	COG1131	(ABC) transporter
H7R23_RS05965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS05975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R23_RS05980	COG4215	(ABC) transporter
H7R23_RS05985	COG4160	amino acid transport
H7R23_RS05990	COG4598	ABC transporter
H7R23_RS06000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R23_RS06005	COG0826	peptidase U32
H7R23_RS06010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R23_RS06015	COG0384	phenazine biosynthesis protein PhzF
H7R23_RS06025	COG1720	tRNA m6t6A37 methyltransferase activity
H7R23_RS06035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7R23_RS06050	COG0642	Histidine kinase
H7R23_RS06060	COG0494	nUDIX hydrolase
H7R23_RS06070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7R23_RS06075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7R23_RS06080	COG3139	Protein of unknown function (DUF1315)
H7R23_RS06090	COG1301	dicarboxylic acid transport
H7R23_RS06095	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS06115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7R23_RS06125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7R23_RS06130	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7R23_RS06150	COG1690	Belongs to the RtcB family
H7R23_RS06155	COG1234	tRNA 3'-trailer cleavage
H7R23_RS06160	COG4650	regulator
H7R23_RS06185	COG2363	Small membrane protein
H7R23_RS06205	COG0513	Belongs to the DEAD box helicase family
H7R23_RS06215	COG0778	Nitroreductase
H7R23_RS06245	COG1286	toxin biosynthetic process
H7R23_RS06270	COG4783	chaperone-mediated protein folding
H7R23_RS06275	COG1610	YqeY-like protein
H7R23_RS06305	COG2815	serine threonine protein kinase
H7R23_RS06305	COG0515	serine threonine protein kinase
H7R23_RS06330	COG1278	Cold shock
H7R23_RS06345	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7R23_RS06350	COG0786	glutamate:sodium symporter activity
H7R23_RS06355	COG0475	glutathione-regulated potassium exporter activity
H7R23_RS06355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7R23_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS06415	COG1309	transcriptional regulator
H7R23_RS06425	COG2985	domain, Protein
H7R23_RS06440	COG2995	paraquat-inducible protein a
H7R23_RS06445	COG3008	intermembrane lipid transfer
H7R23_RS06445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7R23_RS06455	COG2351	hydroxyisourate hydrolase activity
H7R23_RS06470	COG5002	protein histidine kinase activity
H7R23_RS06495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7R23_RS06505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7R23_RS06510	COG0642	Histidine kinase
H7R23_RS06515	COG0745	RESPONSE REGULATOR receiver
H7R23_RS06530	COG1794	racemase activity, acting on amino acids and derivatives
H7R23_RS06560	COG1301	dicarboxylic acid transport
H7R23_RS06570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R23_RS06575	COG2011	ABC-type metal ion transport system permease component
H7R23_RS06580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R23_RS06590	COG0151	Belongs to the GarS family
H7R23_RS06600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H7R23_RS06630	COG2308	Evidence 4 Homologs of previously reported genes of
H7R23_RS06640	COG1305	Transglutaminase-like
H7R23_RS06650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7R23_RS06655	COG0305	Participates in initiation and elongation during chromosome replication
H7R23_RS06680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7R23_RS06685	COG1845	cytochrome c oxidase, subunit III
H7R23_RS06690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7R23_RS06720	COG0726	polysaccharide deacetylase
H7R23_RS06720	COG1649	PFAM Uncharacterised BCR, COG1649
H7R23_RS06725	COG1215	transferase activity, transferring glycosyl groups
H7R23_RS06730	COG3658	cytochrome
H7R23_RS06740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R23_RS06755	COG0583	DNA-binding transcription factor activity
H7R23_RS06770	COG2890	protein-(glutamine-N5) methyltransferase activity
H7R23_RS06775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R23_RS06780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R23_RS06795	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS06800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R23_RS06815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7R23_RS06825	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H7R23_RS06830	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H7R23_RS06840	COG2205	protein histidine kinase activity
H7R23_RS06845	COG0745	RESPONSE REGULATOR receiver
H7R23_RS06850	COG0174	glutamine synthetase
H7R23_RS06865	COG0477	Major facilitator Superfamily
H7R23_RS06870	COG0729	surface antigen
H7R23_RS06900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R23_RS06925	COG0583	DNA-binding transcription factor activity
H7R23_RS06940	COG1187	pseudouridine synthase activity
H7R23_RS06955	COG0564	pseudouridine synthase activity
H7R23_RS06960	COG0802	atpase or kinase
H7R23_RS06965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7R23_RS06975	COG1923	regulation of RNA biosynthetic process
H7R23_RS06980	COG0697	spore germination
H7R23_RS06990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R23_RS07000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R23_RS07005	COG0519	Catalyzes the synthesis of GMP from XMP
H7R23_RS07005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R23_RS07010	COG4302	ethanolamine ammonia-lyase activity
H7R23_RS07015	COG4303	Ethanolamine ammonia lyase large subunit
H7R23_RS07020	COG0531	amino acid
H7R23_RS07040	COG1454	alcohol dehydrogenase
H7R23_RS07045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7R23_RS07070	COG0308	aminopeptidase N
H7R23_RS07110	COG1605	Chorismate mutase
H7R23_RS07125	COG4772	TonB-dependent receptor
H7R23_RS07130	COG4774	siderophore transport
H7R23_RS07195	COG3772	lysozyme
H7R23_RS07220	COG0583	DNA-binding transcription factor activity
H7R23_RS07255	COG0488	(ABC) transporter
H7R23_RS07260	COG0589	response to stress
H7R23_RS07280	COG3135	benzoate transporter
H7R23_RS07285	COG1522	sequence-specific DNA binding
H7R23_RS07295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7R23_RS07300	COG0583	DNA-binding transcription factor activity
H7R23_RS07310	COG0183	Belongs to the thiolase family
H7R23_RS07320	COG2030	dehydratase
H7R23_RS07350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7R23_RS07360	COG0824	Thioesterase
H7R23_RS07365	COG1454	alcohol dehydrogenase
H7R23_RS07390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7R23_RS07420	COG0069	glutamate synthase activity
H7R23_RS07590	COG5410	chromosome segregation
H7R23_RS07595	COG3567	Phage-associated protein, HI1409 family
H7R23_RS07615	COG3566	protein conserved in bacteria
H7R23_RS07725	COG2194	sulfuric ester hydrolase activity
H7R23_RS07730	COG2814	Major facilitator Superfamily
H7R23_RS07745	COG0511	ligase activity, forming carbon-carbon bonds
H7R23_RS07770	COG4264	IucA IucC family
H7R23_RS07780	COG4264	IucA IucC family
H7R23_RS07785	COG2423	ornithine cyclodeaminase activity
H7R23_RS07790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7R23_RS07800	COG1116	anion transmembrane transporter activity
H7R23_RS07800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R23_RS07815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R23_RS07815	COG2146	nitrite reductase [NAD(P)H] activity
H7R23_RS07820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R23_RS07825	COG0243	molybdopterin cofactor binding
H7R23_RS07835	COG0243	molybdopterin cofactor binding
H7R23_RS07840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7R23_RS07855	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7R23_RS07855	COG0315	cyclic pyranopterin monophosphate synthase activity
H7R23_RS07860	COG0303	'Molybdopterin
H7R23_RS07870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R23_RS07875	COG0697	spore germination
H7R23_RS07900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7R23_RS07970	COG2204	response regulator
H7R23_RS07975	COG3852	Histidine kinase
H7R23_RS08000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7R23_RS08005	COG0575	Belongs to the CDS family
H7R23_RS08040	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R23_RS08055	COG2137	regulation of response to DNA damage stimulus
H7R23_RS08065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7R23_RS08070	COG1011	Hydrolase
H7R23_RS08085	COG1522	sequence-specific DNA binding
H7R23_RS08095	COG1113	amino acid transport
H7R23_RS08120	COG0659	secondary active sulfate transmembrane transporter activity
H7R23_RS08155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R23_RS08155	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H7R23_RS08155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R23_RS08160	COG1105	Belongs to the carbohydrate kinase PfkB family
H7R23_RS08165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R23_RS08165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7R23_RS08185	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H7R23_RS08195	COG0024	Methionine aminopeptidase
H7R23_RS08200	COG0583	DNA-binding transcription factor activity
H7R23_RS08210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7R23_RS08215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R23_RS08220	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7R23_RS08220	COG0517	IMP dehydrogenase activity
H7R23_RS08245	COG0552	protein localization to endoplasmic reticulum
H7R23_RS08265	COG4890	Cyd operon protein YbgT
H7R23_RS08270	COG1294	oxidase, subunit
H7R23_RS08285	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7R23_RS08295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R23_RS08310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7R23_RS08315	COG0569	domain protein
H7R23_RS08320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7R23_RS08350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H7R23_RS08355	COG0542	response to heat
H7R23_RS08380	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R23_RS08380	COG1902	pentaerythritol trinitrate reductase activity
H7R23_RS08420	COG0148	phosphopyruvate hydratase activity
H7R23_RS08425	COG2323	membrane
H7R23_RS08460	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7R23_RS08470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R23_RS08475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R23_RS08480	COG0183	Belongs to the thiolase family
H7R23_RS08485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7R23_RS08490	COG0596	Alpha beta hydrolase
H7R23_RS08495	COG2271	Major facilitator Superfamily
H7R23_RS08500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R23_RS08505	COG3485	protocatechuate 3,4-dioxygenase
H7R23_RS08510	COG3485	protocatechuate 3,4-dioxygenase
H7R23_RS08515	COG0710	3-dehydroquinate dehydratase activity
H7R23_RS08520	COG3420	alginic acid biosynthetic process
H7R23_RS08525	COG3659	wide pore channel activity
H7R23_RS08530	COG4993	Dehydrogenase
H7R23_RS08540	COG2391	methyltransferase activity
H7R23_RS08555	COG1414	Transcriptional regulator
H7R23_RS08560	COG0583	DNA-binding transcription factor activity
H7R23_RS08565	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS08590	COG2814	Major facilitator Superfamily
H7R23_RS08600	COG0154	amidase activity
H7R23_RS08620	COG4638	Rieske (2fe-2S)
H7R23_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS08640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R23_RS08650	COG3733	amine oxidase
H7R23_RS08660	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS08665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R23_RS08670	COG0183	Belongs to the thiolase family
H7R23_RS08675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R23_RS08680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R23_RS08690	COG4829	muconolactone delta-isomerase
H7R23_RS08695	COG4948	Mandelate Racemase Muconate Lactonizing
H7R23_RS08700	COG0583	DNA-binding transcription factor activity
H7R23_RS08710	COG2186	Transcriptional regulator
H7R23_RS08730	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS08735	COG2351	hydroxyisourate hydrolase activity
H7R23_RS08740	COG2233	PERMEase
H7R23_RS08750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R23_RS08755	COG2186	Transcriptional regulator
H7R23_RS08765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R23_RS08775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R23_RS08795	COG1902	pentaerythritol trinitrate reductase activity
H7R23_RS08795	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R23_RS08830	COG1309	transcriptional regulator
H7R23_RS08835	COG0583	DNA-binding transcription factor activity
H7R23_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS08860	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS08870	COG0318	PFAM AMP-dependent synthetase and ligase
H7R23_RS08880	COG1309	transcriptional regulator
H7R23_RS08910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7R23_RS08915	COG2259	Doxx family
H7R23_RS08925	COG4993	Dehydrogenase
H7R23_RS08980	COG0583	DNA-binding transcription factor activity
H7R23_RS09005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R23_RS09010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R23_RS09055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R23_RS09070	COG2271	Major facilitator Superfamily
H7R23_RS09095	COG2207	Transcriptional regulator
H7R23_RS09100	COG1064	alcohol dehydrogenase
H7R23_RS09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R23_RS09120	COG1120	ATPase activity
H7R23_RS09140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7R23_RS09225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H7R23_RS09265	COG1073	alpha beta
H7R23_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS09290	COG2207	Transcriptional regulator
H7R23_RS09315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7R23_RS09320	COG1074	ATP-dependent DNA helicase activity
H7R23_RS09380	COG3539	Fimbrial protein
H7R23_RS09405	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H7R23_RS09415	COG0753	catalase activity
H7R23_RS09435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R23_RS09445	COG2205	protein histidine kinase activity
H7R23_RS09450	COG0745	RESPONSE REGULATOR receiver
H7R23_RS09455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS09460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R23_RS09515	COG1535	isochorismatase
H7R23_RS09515	COG3433	isochorismatase activity
H7R23_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS09525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H7R23_RS09530	COG4149	molybdate abc transporter
H7R23_RS09535	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7R23_RS09545	COG4638	Rieske (2fe-2S)
H7R23_RS09550	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7R23_RS09555	COG0543	2 iron, 2 sulfur cluster binding
H7R23_RS09555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R23_RS09570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R23_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS09600	COG2207	Transcriptional regulator
H7R23_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS09610	COG2610	gluconate transmembrane transporter activity
H7R23_RS09650	COG0583	DNA-binding transcription factor activity
H7R23_RS09665	COG2031	fatty acid transporter
H7R23_RS09670	COG0183	Belongs to the thiolase family
H7R23_RS09675	COG0583	DNA-binding transcription factor activity
H7R23_RS09680	COG0583	DNA-binding transcription factor activity
H7R23_RS09695	COG1027	Aspartate ammonia-lyase
H7R23_RS09705	COG0477	Major facilitator Superfamily
H7R23_RS09715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7R23_RS09720	COG1733	regulation of RNA biosynthetic process
H7R23_RS09725	COG2207	Transcriptional regulator
H7R23_RS09725	COG3708	Transcriptional regulator
H7R23_RS09740	COG0730	response to heat
H7R23_RS09760	COG3781	membrane
H7R23_RS09765	COG1063	alcohol dehydrogenase
H7R23_RS09775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R23_RS09780	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R23_RS09785	COG0022	dehydrogenase e1 component
H7R23_RS09790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7R23_RS09795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7R23_RS09810	COG3706	GGDEF domain
H7R23_RS09830	COG0133	tryptophan synthase activity
H7R23_RS09840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R23_RS09870	COG0583	DNA-binding transcription factor activity
H7R23_RS09875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7R23_RS09885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7R23_RS09945	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R23_RS09950	COG4773	Receptor
H7R23_RS09975	COG0730	response to heat
H7R23_RS09980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R23_RS10000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H7R23_RS10015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R23_RS10025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7R23_RS10040	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS10045	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS10050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R23_RS10055	COG2207	Transcriptional regulator
H7R23_RS10060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R23_RS10065	COG0776	regulation of translation
H7R23_RS10090	COG0822	iron-sulfur transferase activity
H7R23_RS10095	COG0316	Belongs to the HesB IscA family
H7R23_RS10125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7R23_RS10145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R23_RS10150	COG0702	epimerase
H7R23_RS10190	COG0601	transmembrane transport
H7R23_RS10195	COG0339	signal peptide processing
H7R23_RS10200	COG4166	transmembrane transport
H7R23_RS10245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7R23_RS10250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7R23_RS10265	COG2431	L-lysine efflux transmembrane transporter activity
H7R23_RS10280	COG0776	regulation of translation
H7R23_RS10345	COG0084	hydrolase, TatD family'
H7R23_RS10365	COG1663	tetraacyldisaccharide 4'-kinase activity
H7R23_RS10370	COG1132	(ABC) transporter
H7R23_RS10380	COG0811	peptide transport
H7R23_RS10385	COG1475	DNA binding
H7R23_RS10390	COG1192	Involved in chromosome partitioning
H7R23_RS10400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7R23_RS10405	COG3178	'Phosphotransferase
H7R23_RS10415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R23_RS10440	COG0424	maF-like protein
H7R23_RS10445	COG2850	peptidyl-arginine hydroxylation
H7R23_RS10455	COG0640	Transcriptional regulator
H7R23_RS10465	COG3619	membrane
H7R23_RS10470	COG3122	Protein conserved in bacteria
H7R23_RS10475	COG1132	(ABC) transporter
H7R23_RS10495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7R23_RS10500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R23_RS10510	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R23_RS10510	COG0506	proline dehydrogenase activity
H7R23_RS10510	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R23_RS10530	COG3698	Phosphodiester glycosidase
H7R23_RS10540	COG2353	YceI-like domain
H7R23_RS10550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7R23_RS10595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7R23_RS10595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7R23_RS10620	COG3539	Fimbrial protein
H7R23_RS10660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7R23_RS10670	COG0583	DNA-binding transcription factor activity
H7R23_RS10685	COG1309	transcriptional regulator
H7R23_RS10700	COG1522	sequence-specific DNA binding
H7R23_RS10710	COG1126	abc transporter atp-binding protein
H7R23_RS10715	COG0765	amino acid transport
H7R23_RS10720	COG0765	amino acid transport
H7R23_RS10750	COG1464	Belongs to the NlpA lipoprotein family
H7R23_RS10760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R23_RS10765	COG2011	ABC-type metal ion transport system permease component
H7R23_RS10770	COG0012	GTP binding
H7R23_RS10795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7R23_RS10835	COG0386	Belongs to the glutathione peroxidase family
H7R23_RS10845	COG0436	Aminotransferase
H7R23_RS10850	COG1301	dicarboxylic acid transport
H7R23_RS10885	COG3634	alkyl hydroperoxide reductase activity
H7R23_RS10900	COG0583	DNA-binding transcription factor activity
H7R23_RS10905	COG0431	NADPH-dependent FMN reductase
H7R23_RS10910	COG0798	PFAM Bile acid sodium symporter
H7R23_RS10920	COG0640	Transcriptional regulator
H7R23_RS10935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7R23_RS10945	COG0583	DNA-binding transcription factor activity
H7R23_RS10955	COG1953	Uracil, thiamine, allantoin
H7R23_RS10965	COG2175	clavaminate synthase activity
H7R23_RS10970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R23_RS10975	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7R23_RS10980	COG4521	taurine ABC transporter
H7R23_RS10990	COG0477	Major facilitator Superfamily
H7R23_RS11010	COG1271	oxidase subunit
H7R23_RS11015	COG1294	oxidase, subunit
H7R23_RS11025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R23_RS11045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7R23_RS11065	COG3052	prosthetic group binding
H7R23_RS11070	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H7R23_RS11095	COG1346	cytolysis
H7R23_RS11105	COG0583	DNA-binding transcription factor activity
H7R23_RS11110	COG0625	glutathione transferase activity
H7R23_RS11115	COG0625	glutathione transferase activity
H7R23_RS11135	COG0583	DNA-binding transcription factor activity
H7R23_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS11150	COG1045	serine acetyltransferase
H7R23_RS11155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R23_RS11160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7R23_RS11165	COG1280	lysine exporter protein (LysE YggA)
H7R23_RS11180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R23_RS11185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R23_RS11195	COG0765	amino acid transport
H7R23_RS11200	COG0765	amino acid transport
H7R23_RS11240	COG2205	protein histidine kinase activity
H7R23_RS11240	COG0784	Response regulator, receiver
H7R23_RS11260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7R23_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS11325	COG0583	DNA-binding transcription factor activity
H7R23_RS11335	COG2814	Major facilitator Superfamily
H7R23_RS11350	COG0318	PFAM AMP-dependent synthetase and ligase
H7R23_RS11355	COG1309	transcriptional regulator
H7R23_RS11360	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS11365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7R23_RS11370	COG1024	Enoyl-CoA hydratase
H7R23_RS11375	COG4770	biotin carboxylase activity
H7R23_RS11385	COG0583	DNA-binding transcription factor activity
H7R23_RS11400	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS11410	COG2814	Major facilitator Superfamily
H7R23_RS11420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R23_RS11425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R23_RS11430	COG2814	Major facilitator Superfamily
H7R23_RS11435	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS11440	COG1024	Enoyl-CoA hydratase
H7R23_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS11450	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R23_RS11455	COG0183	Belongs to the thiolase family
H7R23_RS11465	COG2814	Major facilitator Superfamily
H7R23_RS11475	COG1024	Enoyl-CoA hydratase
H7R23_RS11485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7R23_RS11490	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS11495	COG2814	Major facilitator Superfamily
H7R23_RS11500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R23_RS11505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7R23_RS11520	COG3842	ATPase activity
H7R23_RS11525	COG1840	ABC-type Fe3 transport system, periplasmic component
H7R23_RS11540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R23_RS11545	COG1414	Transcriptional regulator
H7R23_RS11600	COG2050	protein possibly involved in aromatic compounds catabolism
H7R23_RS11610	COG3327	negative regulation of DNA-templated transcription, initiation
H7R23_RS11615	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H7R23_RS11620	COG0183	Belongs to the thiolase family
H7R23_RS11625	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R23_RS11630	COG1024	Enoyl-CoA hydratase
H7R23_RS11635	COG1024	Enoyl-CoA hydratase
H7R23_RS11640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R23_RS11645	COG2151	metal-sulfur cluster biosynthetic enzyme
H7R23_RS11650	COG3396	Phenylacetate-CoA oxygenase
H7R23_RS11655	COG3460	Phenylacetate-CoA oxygenase
H7R23_RS11660	COG3396	Phenylacetate-CoA oxygenase
H7R23_RS11665	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS11665	COG2030	dehydratase
H7R23_RS11670	COG1760	l-serine dehydratase
H7R23_RS11685	COG0789	Transcriptional regulator
H7R23_RS11695	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7R23_RS11700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R23_RS11715	COG2807	transmembrane transport
H7R23_RS11720	COG0590	tRNA wobble adenosine to inosine editing
H7R23_RS11770	COG2885	chlorophyll binding
H7R23_RS11905	COG1116	anion transmembrane transporter activity
H7R23_RS11910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R23_RS11920	COG0864	Transcriptional regulator
H7R23_RS11935	COG1733	regulation of RNA biosynthetic process
H7R23_RS11940	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R23_RS11945	COG0439	Biotin carboxylase
H7R23_RS11960	COG1063	alcohol dehydrogenase
H7R23_RS11965	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R23_RS12000	COG3210	domain, Protein
H7R23_RS12005	COG2831	hemolysin activation secretion protein
H7R23_RS12010	COG0038	chloride channel
H7R23_RS12015	COG4770	biotin carboxylase activity
H7R23_RS12035	COG1914	H( )-stimulated, divalent metal cation uptake system
H7R23_RS12040	COG0583	DNA-binding transcription factor activity
H7R23_RS12050	COG1595	DNA-templated transcription, initiation
H7R23_RS12060	COG3220	belongs to the UPF0276 family
H7R23_RS12120	COG1309	transcriptional regulator
H7R23_RS12135	COG0657	acetylesterase activity
H7R23_RS12175	COG3038	cytochrome b561
H7R23_RS12180	COG0753	catalase activity
H7R23_RS12195	COG2207	Transcriptional regulator
H7R23_RS12215	COG1278	Cold shock
H7R23_RS12245	COG0531	amino acid
H7R23_RS12250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7R23_RS12265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R23_RS12280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H7R23_RS12290	COG4122	O-methyltransferase activity
H7R23_RS12320	COG1538	Outer membrane efflux protein
H7R23_RS12325	COG1137	ATPase activity
H7R23_RS12330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H7R23_RS12340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7R23_RS12395	COG2814	Major facilitator Superfamily
H7R23_RS12405	COG0668	transmembrane transport
H7R23_RS12450	COG1309	transcriptional regulator
H7R23_RS12460	COG2226	methyltransferase
H7R23_RS12485	COG1278	Cold shock
H7R23_RS12490	COG1560	Kdo2-lipid A biosynthetic process
H7R23_RS12495	COG1280	lysine exporter protein (LysE YggA)
H7R23_RS12530	COG1570	exodeoxyribonuclease VII activity
H7R23_RS12610	COG2871	sodium ion transport
H7R23_RS12620	COG0583	DNA-binding transcription factor activity
H7R23_RS12630	COG4638	Rieske (2fe-2S)
H7R23_RS12635	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7R23_RS12640	COG0543	2 iron, 2 sulfur cluster binding
H7R23_RS12640	COG0633	Ferredoxin
H7R23_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS12650	COG3135	benzoate transporter
H7R23_RS12655	COG2814	Major facilitator Superfamily
H7R23_RS12670	COG1643	Atp-dependent helicase
H7R23_RS12695	COG3634	alkyl hydroperoxide reductase activity
H7R23_RS12715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7R23_RS12720	COG0625	glutathione transferase activity
H7R23_RS12730	COG2885	chlorophyll binding
H7R23_RS12765	COG0542	response to heat
H7R23_RS12780	COG1765	OsmC-like protein
H7R23_RS12795	COG0667	Aldo Keto reductase
H7R23_RS12810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7R23_RS12820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7R23_RS12830	COG0527	aspartate kinase activity
H7R23_RS12840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7R23_RS12850	COG3038	cytochrome b561
H7R23_RS12855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7R23_RS12860	COG2252	PERMEase
H7R23_RS12870	COG1741	Belongs to the pirin family
H7R23_RS12875	COG1309	transcriptional regulator
H7R23_RS12890	COG2072	flavoprotein involved in K transport
H7R23_RS12895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7R23_RS12900	COG0583	DNA-binding transcription factor activity
H7R23_RS12915	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R23_RS12945	COG1944	ATP diphosphatase activity
H7R23_RS12965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7R23_RS12980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R23_RS12995	COG2814	Major facilitator Superfamily
H7R23_RS13000	COG1024	Enoyl-CoA hydratase
H7R23_RS13005	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS13015	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS13040	COG2186	Transcriptional regulator
H7R23_RS13045	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS13055	COG4948	Mandelate Racemase Muconate Lactonizing
H7R23_RS13060	COG2271	Major facilitator Superfamily
H7R23_RS13065	COG2721	sulfolactate sulfo-lyase activity
H7R23_RS13070	COG0697	spore germination
H7R23_RS13090	COG1113	amino acid transport
H7R23_RS13110	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS13130	COG0531	amino acid
H7R23_RS13140	COG1113	amino acid transport
H7R23_RS13200	COG2059	Chromate
H7R23_RS13210	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H7R23_RS13220	COG1230	cation diffusion facilitator family transporter
H7R23_RS13235	COG2814	Major facilitator Superfamily
H7R23_RS13355	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R23_RS13355	COG1902	pentaerythritol trinitrate reductase activity
H7R23_RS13365	COG4251	negative regulation of phosphorylation
H7R23_RS13365	COG3706	GGDEF domain
H7R23_RS13365	COG5001	Diguanylate cyclase
H7R23_RS13365	COG2203	Gaf domain
H7R23_RS13375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R23_RS13395	COG4172	Belongs to the ABC transporter superfamily
H7R23_RS13400	COG4239	(ABC) transporter, permease
H7R23_RS13405	COG4174	ABC transporter (Permease)
H7R23_RS13410	COG4166	transmembrane transport
H7R23_RS13415	COG0741	lytic transglycosylase activity
H7R23_RS13415	COG1388	LysM domain
H7R23_RS13460	COG0583	DNA-binding transcription factor activity
H7R23_RS13465	COG1279	arginine transmembrane transporter activity
H7R23_RS13475	COG0789	Transcriptional regulator
H7R23_RS13485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R23_RS13490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R23_RS13495	COG0006	proline dipeptidase activity
H7R23_RS13535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7R23_RS13550	COG3384	dioxygenase
H7R23_RS13560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R23_RS13565	COG2878	Part of a membrane complex involved in electron transport
H7R23_RS13570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7R23_RS13595	COG0768	penicillin binding
H7R23_RS13600	COG0742	ribosomal rna small subunit methyltransferase
H7R23_RS13615	COG0830	nickel cation binding
H7R23_RS13625	COG0804	urea catabolic process
H7R23_RS13650	COG3015	lipoprotein NlpE involved in copper resistance
H7R23_RS13665	COG1253	flavin adenine dinucleotide binding
H7R23_RS13670	COG2851	Citrate transporter
H7R23_RS13720	COG1773	rubredoxin
H7R23_RS13725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R23_RS13730	COG2267	carboxylic ester hydrolase activity
H7R23_RS13735	COG0583	DNA-binding transcription factor activity
H7R23_RS13765	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7R23_RS13770	COG4181	ATPase activity
H7R23_RS13815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7R23_RS13835	COG0306	phosphate transporter
H7R23_RS13865	COG3958	Transketolase
H7R23_RS13870	COG3959	Transketolase, thiamine diphosphate binding domain
H7R23_RS13875	COG2271	Major facilitator Superfamily
H7R23_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS13885	COG0583	DNA-binding transcription factor activity
H7R23_RS13905	COG2223	nitrite transmembrane transporter activity
H7R23_RS13910	COG2207	Transcriptional regulator
H7R23_RS13915	COG2066	Belongs to the glutaminase family
H7R23_RS13920	COG0242	peptide deformylase activity
H7R23_RS13925	COG0477	Major facilitator Superfamily
H7R23_RS13935	COG0028	Belongs to the TPP enzyme family
H7R23_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS13955	COG2267	carboxylic ester hydrolase activity
H7R23_RS13965	COG2271	Major facilitator Superfamily
H7R23_RS13980	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS14000	COG1414	Transcriptional regulator
H7R23_RS14015	COG1024	Enoyl-CoA hydratase
H7R23_RS14025	COG1215	transferase activity, transferring glycosyl groups
H7R23_RS14030	COG0726	polysaccharide deacetylase
H7R23_RS14030	COG1649	PFAM Uncharacterised BCR, COG1649
H7R23_RS14040	COG4681	YaeQ
H7R23_RS14050	COG0523	cobalamin synthesis protein
H7R23_RS14060	COG1607	acyl-coa hydrolase
H7R23_RS14070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R23_RS14075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R23_RS14080	COG1309	transcriptional regulator
H7R23_RS14105	COG2040	homocysteine
H7R23_RS14110	COG0531	amino acid
H7R23_RS14165	COG1595	DNA-templated transcription, initiation
H7R23_RS14175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R23_RS14180	COG0477	Major facilitator Superfamily
H7R23_RS14280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R23_RS14360	COG0592	DNA-directed DNA polymerase activity
H7R23_RS14525	COG3755	Protein conserved in bacteria
H7R23_RS14570	COG1484	DNA-dependent DNA replication
H7R23_RS14675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R23_RS14745	COG0405	Gamma-glutamyltransferase
H7R23_RS14750	COG2814	Major facilitator Superfamily
H7R23_RS14760	COG2050	protein possibly involved in aromatic compounds catabolism
H7R23_RS14775	COG1090	epimerase
H7R23_RS14795	COG0420	3'-5' exonuclease activity
H7R23_RS14820	COG0735	belongs to the Fur family
H7R23_RS14825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R23_RS14830	COG2914	Belongs to the UPF0125 (RnfH) family
H7R23_RS14845	COG0121	glutamine amidotransferase
H7R23_RS14860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7R23_RS14870	COG0210	DNA helicase
H7R23_RS14875	COG2885	chlorophyll binding
H7R23_RS14880	COG0204	Acyl-transferase
H7R23_RS14895	COG2894	cell division
H7R23_RS14915	COG1280	lysine exporter protein (LysE YggA)
H7R23_RS14920	COG1674	ftsk spoiiie
H7R23_RS14925	COG0492	ferredoxin-NADP+ reductase activity
H7R23_RS14930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H7R23_RS14940	COG0456	acetyltransferase
H7R23_RS14955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7R23_RS14960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7R23_RS14970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7R23_RS14985	COG1981	membrane
H7R23_RS14995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7R23_RS14995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R23_RS15015	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS15020	COG4638	Rieske (2fe-2S)
H7R23_RS15025	COG0657	acetylesterase activity
H7R23_RS15035	COG0473	3-isopropylmalate dehydrogenase activity
H7R23_RS15040	COG0583	DNA-binding transcription factor activity
H7R23_RS15060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R23_RS15095	COG0358	DNA primase activity
H7R23_RS15110	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H7R23_RS15140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7R23_RS15170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7R23_RS15180	COG0351	phosphomethylpyrimidine kinase
H7R23_RS15180	COG0352	thiamine-phosphate diphosphorylase activity
H7R23_RS15180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7R23_RS15185	COG1652	LysM domain
H7R23_RS15210	COG1399	metal-binding, possibly nucleic acid-binding protein
H7R23_RS15215	COG3101	peptidyl-lysine hydroxylation
H7R23_RS15220	COG0009	L-threonylcarbamoyladenylate synthase
H7R23_RS15225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7R23_RS15230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7R23_RS15245	COG4106	trans-aconitate 2-methyltransferase activity
H7R23_RS15260	COG0596	Alpha beta hydrolase
H7R23_RS15260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R23_RS15260	COG2226	methyltransferase
H7R23_RS15270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H7R23_RS15275	COG2223	nitrite transmembrane transporter activity
H7R23_RS15295	COG1196	nuclear chromosome segregation
H7R23_RS15305	COG0730	response to heat
H7R23_RS15320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7R23_RS15330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R23_RS15380	COG0489	protein tyrosine kinase activity
H7R23_RS15390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R23_RS15390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R23_RS15425	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H7R23_RS15430	COG2081	HI0933 family
H7R23_RS15440	COG0668	transmembrane transport
H7R23_RS15460	COG0583	DNA-binding transcription factor activity
H7R23_RS15465	COG1278	Cold shock
H7R23_RS15480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R23_RS15485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7R23_RS15515	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H7R23_RS15540	COG2199	diguanylate cyclase activity
H7R23_RS15555	COG0745	RESPONSE REGULATOR receiver
H7R23_RS15570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R23_RS15615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R23_RS15630	COG0583	DNA-binding transcription factor activity
H7R23_RS15680	COG0583	DNA-binding transcription factor activity
H7R23_RS15695	COG0583	DNA-binding transcription factor activity
H7R23_RS15700	COG1053	succinate dehydrogenase
H7R23_RS15715	COG1309	transcriptional regulator
H7R23_RS15725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7R23_RS15730	COG2814	Major facilitator Superfamily
H7R23_RS15735	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS15740	COG0583	DNA-binding transcription factor activity
H7R23_RS15745	COG1063	alcohol dehydrogenase
H7R23_RS15760	COG0582	viral genome integration into host DNA
H7R23_RS15765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R23_RS15960	COG3409	Peptidoglycan-binding domain 1 protein
H7R23_RS15960	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7R23_RS16005	COG4695	Portal protein
H7R23_RS16035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7R23_RS16040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7R23_RS16045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7R23_RS16065	COG2132	Multicopper oxidase
H7R23_RS16075	COG0561	phosphatase activity
H7R23_RS16080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7R23_RS16105	COG1214	PFAM Peptidase M22, glycoprotease
H7R23_RS16165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7R23_RS16170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7R23_RS16175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7R23_RS16235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R23_RS16245	COG1846	Transcriptional regulator
H7R23_RS16250	COG1764	response to oxidative stress
H7R23_RS16290	COG0037	tRNA processing
H7R23_RS16330	COG0072	phenylalanine-tRNA ligase activity
H7R23_RS16360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7R23_RS16375	COG1238	metal cluster binding
H7R23_RS16380	COG0625	glutathione transferase activity
H7R23_RS16395	COG0318	PFAM AMP-dependent synthetase and ligase
H7R23_RS16400	COG3028	Belongs to the UPF0307 family
H7R23_RS16405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R23_RS16425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7R23_RS16430	COG0617	tRNA 3'-terminal CCA addition
H7R23_RS16435	COG1555	photosystem II stabilization
H7R23_RS16440	COG3956	TIGRFAM MazG family protein
H7R23_RS16445	COG4221	oxidoreductase activity
H7R23_RS16450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R23_RS16470	COG0784	Response regulator, receiver
H7R23_RS16470	COG2205	protein histidine kinase activity
H7R23_RS16470	COG5002	protein histidine kinase activity
H7R23_RS16475	COG1024	Enoyl-CoA hydratase
H7R23_RS16480	COG2084	Dehydrogenase
H7R23_RS16485	COG3622	Belongs to the hyi family
H7R23_RS16515	COG0697	spore germination
H7R23_RS16525	COG2814	Major facilitator Superfamily
H7R23_RS16565	COG2072	flavoprotein involved in K transport
H7R23_RS16570	COG0492	ferredoxin-NADP+ reductase activity
H7R23_RS16575	COG0431	NADPH-dependent FMN reductase
H7R23_RS16580	COG0798	PFAM Bile acid sodium symporter
H7R23_RS16590	COG0640	Transcriptional regulator
H7R23_RS16650	COG2132	Multicopper oxidase
H7R23_RS16665	COG2205	protein histidine kinase activity
H7R23_RS16755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R23_RS16770	COG0583	DNA-binding transcription factor activity
H7R23_RS16780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7R23_RS16795	COG0084	hydrolase, TatD family'
H7R23_RS16810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H7R23_RS16830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7R23_RS16835	COG0440	acetolactate synthase activity
H7R23_RS16840	COG0028	Belongs to the TPP enzyme family
H7R23_RS16860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R23_RS16865	COG1136	(ABC) transporter
H7R23_RS16865	COG0577	efflux transmembrane transporter activity
H7R23_RS16885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H7R23_RS16890	COG1162	GTPase activity
H7R23_RS16900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7R23_RS16920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R23_RS16940	COG1426	Protein conserved in bacteria
H7R23_RS16975	COG0793	Belongs to the peptidase S41A family
H7R23_RS16990	COG2267	carboxylic ester hydrolase activity
H7R23_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
H7R23_RS17005	COG3265	gluconokinase activity
H7R23_RS17015	COG0800	Aldolase
H7R23_RS17030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7R23_RS17035	COG0857	belongs to the CobB CobQ family
H7R23_RS17035	COG0280	phosphate acetyltransferase
H7R23_RS17040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R23_RS17040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R23_RS17060	COG0740	serine-type endopeptidase activity
H7R23_RS17070	COG4774	siderophore transport
H7R23_RS17080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7R23_RS17090	COG2813	Specifically methylates the guanine in position
H7R23_RS17090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R23_RS17190	COG0788	formyltetrahydrofolate deformylase activity
H7R23_RS17215	COG4651	solute:proton antiporter activity
H7R23_RS17215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7R23_RS17235	COG0724	RNA recognition motif
H7R23_RS17240	COG0210	DNA helicase
H7R23_RS17265	COG1733	regulation of RNA biosynthetic process
H7R23_RS17275	COG2900	Belongs to the SlyX family
H7R23_RS17280	COG0488	(ABC) transporter
H7R23_RS17290	COG1560	Kdo2-lipid A biosynthetic process
H7R23_RS17300	COG1301	dicarboxylic acid transport
H7R23_RS17355	COG0473	3-isopropylmalate dehydrogenase activity
H7R23_RS17380	COG0583	DNA-binding transcription factor activity
H7R23_RS17420	COG0583	DNA-binding transcription factor activity
H7R23_RS17430	COG0625	glutathione transferase activity
H7R23_RS17435	COG2378	regulation of single-species biofilm formation
H7R23_RS17440	COG0546	phosphoglycolate phosphatase activity
H7R23_RS17450	COG1530	ribonuclease E activity
H7R23_RS17455	COG0318	PFAM AMP-dependent synthetase and ligase
H7R23_RS17470	COG0583	DNA-binding transcription factor activity
H7R23_RS17475	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS17480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7R23_RS17490	COG0534	Mate efflux family protein
H7R23_RS17505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7R23_RS17530	COG0493	'glutamate synthase
H7R23_RS17540	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H7R23_RS17545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R23_RS17560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7R23_RS17570	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H7R23_RS17570	COG0644	oxidoreductase
H7R23_RS17585	COG4535	Mg2 and Co2 transporter CorC
H7R23_RS17595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R23_RS17615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7R23_RS17625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7R23_RS17635	COG0484	heat shock protein binding
H7R23_RS17640	COG0789	Transcriptional regulator
H7R23_RS17645	COG0598	Magnesium transport protein CorA
H7R23_RS17650	COG1185	polyribonucleotide nucleotidyltransferase activity
H7R23_RS17660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7R23_RS17665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7R23_RS17670	COG1074	ATP-dependent DNA helicase activity
H7R23_RS17675	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H7R23_RS17695	COG2226	methyltransferase
H7R23_RS17705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7R23_RS17720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7R23_RS17735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7R23_RS17735	COG2111	Na H antiporter
H7R23_RS17740	COG1006	Multisubunit Na H antiporter MnhC subunit
H7R23_RS17745	COG0651	ATP synthesis coupled electron transport
H7R23_RS17750	COG1863	multisubunit Na H antiporter MnhE subunit
H7R23_RS17755	COG2212	antiporter activity
H7R23_RS17760	COG1320	monovalent cation:proton antiporter activity
H7R23_RS17765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7R23_RS17775	COG0195	Participates in both transcription termination and antitermination
H7R23_RS17825	COG0237	dephospho-CoA kinase activity
H7R23_RS17835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R23_RS17850	COG0497	DNA recombination
H7R23_RS17860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7R23_RS17895	COG2169	Transcriptional regulator
H7R23_RS17895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7R23_RS17900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7R23_RS17970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7R23_RS17985	COG0326	Molecular chaperone. Has ATPase activity
H7R23_RS18000	COG2056	Na+-H+ antiporter family
H7R23_RS18070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7R23_RS18100	COG0546	phosphoglycolate phosphatase activity
H7R23_RS18105	COG1716	ATPase activity
H7R23_RS18150	COG0181	hydroxymethylbilane synthase activity
H7R23_RS18160	COG3275	phosphorelay sensor kinase activity
H7R23_RS18180	COG1538	Outer membrane efflux protein
H7R23_RS18190	COG0697	spore germination
H7R23_RS18210	COG0494	nUDIX hydrolase
H7R23_RS18215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7R23_RS18220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7R23_RS18225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R23_RS18230	COG0772	Belongs to the SEDS family
H7R23_RS18255	COG4974	Belongs to the 'phage' integrase family
H7R23_RS18260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R23_RS18270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7R23_RS18280	COG2197	response regulator
H7R23_RS18295	COG0793	Belongs to the peptidase S41A family
H7R23_RS18300	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7R23_RS18305	COG0795	lipopolysaccharide-transporting ATPase activity
H7R23_RS18345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R23_RS18345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R23_RS18355	COG0004	ammonium transporteR
H7R23_RS18360	COG0347	Belongs to the P(II) protein family
H7R23_RS18370	COG0606	chelatase, subunit chli
H7R23_RS18375	COG0431	NADPH-dependent FMN reductase
H7R23_RS18380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R23_RS18385	COG0235	Class ii aldolase
H7R23_RS18390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R23_RS18410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7R23_RS18425	COG0318	PFAM AMP-dependent synthetase and ligase
H7R23_RS18435	COG0477	Major facilitator Superfamily
H7R23_RS18440	COG2860	membrane
H7R23_RS18450	COG1253	flavin adenine dinucleotide binding
H7R23_RS18460	COG2814	Major facilitator Superfamily
H7R23_RS18470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R23_RS18510	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7R23_RS18525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7R23_RS18555	COG1309	transcriptional regulator
H7R23_RS18590	COG0758	DNA mediated transformation
H7R23_RS18600	COG0697	spore germination
H7R23_RS18605	COG1309	transcriptional regulator
H7R23_RS18620	COG0386	Belongs to the glutathione peroxidase family
H7R23_RS18635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7R23_RS18645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7R23_RS18685	COG1121	(ABC) transporter
H7R23_RS18690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R23_RS18695	COG1280	lysine exporter protein (LysE YggA)
H7R23_RS18700	COG2837	iron assimilation
H7R23_RS18705	COG0281	malic enzyme
H7R23_RS18750	COG0519	Catalyzes the synthesis of GMP from XMP
H7R23_RS18750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R23_RS18755	COG4399	Belongs to the UPF0754 family
H7R23_RS18760	COG2259	Doxx family
H7R23_RS18765	COG0586	Pfam SNARE associated Golgi protein
H7R23_RS18780	COG1192	Involved in chromosome partitioning
H7R23_RS18790	COG0271	Belongs to the BolA IbaG family
H7R23_RS18830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7R23_RS18830	COG3321	synthase
H7R23_RS18830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7R23_RS18830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H7R23_RS18835	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS18840	COG0318	PFAM AMP-dependent synthetase and ligase
H7R23_RS18845	COG2197	response regulator
H7R23_RS18855	COG3916	Acyl-homoserine-lactone synthase
H7R23_RS18860	COG0477	Major facilitator Superfamily
H7R23_RS18865	COG1024	Enoyl-CoA hydratase
H7R23_RS18870	COG1024	Enoyl-CoA hydratase
H7R23_RS18875	COG1960	acyl-CoA dehydrogenase activity
H7R23_RS18880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R23_RS18900	COG1113	amino acid transport
H7R23_RS18905	COG1113	amino acid transport
H7R23_RS18910	COG0251	oxidation-reduction process
H7R23_RS18950	COG0564	pseudouridine synthase activity
H7R23_RS19015	COG1051	belongs to the nudix hydrolase family
H7R23_RS19060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7R23_RS19075	COG1802	Transcriptional regulator
H7R23_RS19085	COG1448	Aminotransferase
H7R23_RS19090	COG0277	FAD linked oxidase domain protein
H7R23_RS19100	COG2186	Transcriptional regulator
H7R23_RS19110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7R23_RS19125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7R23_RS19130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7R23_RS19165	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7R23_RS19190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H7R23_RS19220	COG0728	peptidoglycan biosynthetic process
H7R23_RS19225	COG3023	N-Acetylmuramoyl-L-alanine amidase
H7R23_RS19280	COG0546	phosphoglycolate phosphatase activity
H7R23_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
H7R23_RS19300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7R23_RS19300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7R23_RS19305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R23_RS19310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R23_RS19315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R23_RS19320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R23_RS19325	COG1116	anion transmembrane transporter activity
H7R23_RS19330	COG1309	transcriptional regulator
H7R23_RS19335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7R23_RS19345	COG0196	riboflavin kinase activity
H7R23_RS19350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7R23_RS19360	COG1047	Peptidyl-prolyl cis-trans
H7R23_RS19400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7R23_RS19405	COG0657	acetylesterase activity
H7R23_RS19455	COG2951	lytic endotransglycosylase activity
H7R23_RS19460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7R23_RS19475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7R23_RS19485	COG0671	phosphoesterase, PA-phosphatase related
H7R23_RS19490	COG0861	Integral membrane protein TerC family
H7R23_RS19500	COG0754	glutathionylspermidine amidase activity
H7R23_RS19510	COG0402	S-adenosylhomocysteine deaminase activity
H7R23_RS19525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R23_RS19530	COG1230	cation diffusion facilitator family transporter
H7R23_RS19545	COG0706	membrane insertase activity
H7R23_RS19595	COG3077	Addiction module antitoxin, RelB DinJ family
H7R23_RS19630	COG4221	oxidoreductase activity
H7R23_RS19635	COG0583	DNA-binding transcription factor activity
H7R23_RS19640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H7R23_RS19655	COG0697	spore germination
H7R23_RS19660	COG0477	Major facilitator Superfamily
H7R23_RS19690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H7R23_RS19705	COG1979	alcohol dehydrogenase
H7R23_RS19715	COG1902	pentaerythritol trinitrate reductase activity
H7R23_RS19725	COG1309	transcriptional regulator
H7R23_RS19730	COG2130	NADP-dependent
H7R23_RS19745	COG0582	viral genome integration into host DNA
H7R23_RS19790	COG2207	Transcriptional regulator
H7R23_RS19795	COG0633	Ferredoxin
H7R23_RS19820	COG1309	transcriptional regulator
H7R23_RS19860	COG1373	ATPase (AAA superfamily
H7R23_RS19905	COG3038	cytochrome b561
H7R23_RS20000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair