locus-tag	class	description
BVD86_RS00040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVD86_RS00060	COG0823	Involved in the tonB-independent uptake of proteins
BVD86_RS00080	COG0824	Thioesterase
BVD86_RS00085	COG1473	amidohydrolase
BVD86_RS00105	COG0047	phosphoribosylformylglycinamidine synthase activity
BVD86_RS00105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVD86_RS00110	COG2814	Major facilitator Superfamily
BVD86_RS00115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVD86_RS00120	COG1024	Enoyl-CoA hydratase
BVD86_RS00125	COG1056	cytidyltransferase-related domain
BVD86_RS00125	COG1051	belongs to the nudix hydrolase family
BVD86_RS00140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVD86_RS00155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVD86_RS00170	COG4625	pathogenesis
BVD86_RS00175	COG0583	DNA-binding transcription factor activity
BVD86_RS00180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVD86_RS00185	COG4208	sulfate ABC transporter
BVD86_RS00190	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BVD86_RS00200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BVD86_RS00205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVD86_RS00210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVD86_RS00230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVD86_RS00240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVD86_RS00245	COG0481	GTPase activity
BVD86_RS00250	COG0681	Belongs to the peptidase S26 family
BVD86_RS00260	COG0571	ribonuclease III activity
BVD86_RS00265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVD86_RS00275	COG1381	Involved in DNA repair and RecF pathway recombination
BVD86_RS00280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BVD86_RS00290	COG4221	oxidoreductase activity
BVD86_RS00320	COG0436	Aminotransferase
BVD86_RS00340	COG0556	nucleotide-excision repair
BVD86_RS00350	COG2962	Rard protein
BVD86_RS00395	COG2070	2-Nitropropane dioxygenase
BVD86_RS00420	COG1215	transferase activity, transferring glycosyl groups
BVD86_RS00435	COG0415	Belongs to the DNA photolyase family
BVD86_RS00445	COG1252	NADH dehydrogenase
BVD86_RS00450	COG1686	Belongs to the peptidase S11 family
BVD86_RS00465	COG1187	pseudouridine synthase activity
BVD86_RS00475	COG0477	Major facilitator Superfamily
BVD86_RS00480	COG0583	DNA-binding transcription factor activity
BVD86_RS00485	COG1823	symporter activity
BVD86_RS00495	COG0612	Peptidase, M16
BVD86_RS00520	COG0352	thiamine-phosphate diphosphorylase activity
BVD86_RS00555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_RS00570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVD86_RS00575	COG0076	glutamate decarboxylase activity
BVD86_RS00585	COG1522	sequence-specific DNA binding
BVD86_RS00590	COG3961	Belongs to the TPP enzyme family
BVD86_RS00595	COG1113	amino acid transport
BVD86_RS00600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVD86_RS00605	COG0573	inorganic phosphate transmembrane transporter activity
BVD86_RS00615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVD86_RS00620	COG0616	signal peptide processing
BVD86_RS00655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVD86_RS00660	COG1686	Belongs to the peptidase S11 family
BVD86_RS00685	COG0583	DNA-binding transcription factor activity
BVD86_RS00690	COG1067	ATP-dependent peptidase activity
BVD86_RS00730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVD86_RS00735	COG1966	Carbon starvation protein
BVD86_RS00740	COG2879	small protein
BVD86_RS00750	COG0582	viral genome integration into host DNA
BVD86_RS00780	COG2026	Addiction module toxin, RelE StbE family
BVD86_RS00795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BVD86_RS00875	COG2964	Protein conserved in bacteria
BVD86_RS00885	COG1741	Belongs to the pirin family
BVD86_RS00900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_RS00905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVD86_RS00910	COG4605	iron ion homeostasis
BVD86_RS00915	COG4604	ABC transporter, ATP-binding protein
BVD86_RS00920	COG4607	ABC-type enterochelin transport system periplasmic component
BVD86_RS00925	COG4774	siderophore transport
BVD86_RS00935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_RS00940	COG1021	2,3-dihydroxybenzoate-AMP ligase
BVD86_RS00945	COG3433	isochorismatase activity
BVD86_RS00945	COG1535	isochorismatase
BVD86_RS00960	COG1132	(ABC) transporter
BVD86_RS00965	COG1132	(ABC) transporter
BVD86_RS00970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BVD86_RS00980	COG1169	isochorismate synthase
BVD86_RS01000	COG3739	integral membrane protein
BVD86_RS01020	COG0302	gtp cyclohydrolase
BVD86_RS01030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVD86_RS01040	COG2840	Smr protein MutS2
BVD86_RS01055	COG0512	Glutamine amidotransferase of anthranilate synthase
BVD86_RS01070	COG0174	glutamine synthetase
BVD86_RS01080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVD86_RS01115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVD86_RS01120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVD86_RS01125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVD86_RS01145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVD86_RS01150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVD86_RS01155	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BVD86_RS01170	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS01175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVD86_RS01180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_RS01190	COG2223	nitrite transmembrane transporter activity
BVD86_RS01200	COG0024	Methionine aminopeptidase
BVD86_RS01205	COG0052	Belongs to the universal ribosomal protein uS2 family
BVD86_RS01220	COG2207	Transcriptional regulator
BVD86_RS01245	COG2951	lytic endotransglycosylase activity
BVD86_RS01250	COG0772	Belongs to the SEDS family
BVD86_RS01265	COG0842	Transport permease protein
BVD86_RS01270	COG1131	(ABC) transporter
BVD86_RS01315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS01325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_RS01330	COG4215	(ABC) transporter
BVD86_RS01335	COG4160	amino acid transport
BVD86_RS01340	COG4598	ABC transporter
BVD86_RS01350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVD86_RS01355	COG0826	peptidase U32
BVD86_RS01360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_RS01365	COG0384	phenazine biosynthesis protein PhzF
BVD86_RS01375	COG1720	tRNA m6t6A37 methyltransferase activity
BVD86_RS01385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVD86_RS01400	COG0642	Histidine kinase
BVD86_RS01410	COG0494	nUDIX hydrolase
BVD86_RS01420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVD86_RS01425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVD86_RS01430	COG3139	Protein of unknown function (DUF1315)
BVD86_RS01435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVD86_RS01445	COG1301	dicarboxylic acid transport
BVD86_RS01450	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS01465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVD86_RS01475	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVD86_RS01480	COG1234	tRNA 3'-trailer cleavage
BVD86_RS01510	COG2363	Small membrane protein
BVD86_RS01530	COG0513	Belongs to the DEAD box helicase family
BVD86_RS01540	COG0778	Nitroreductase
BVD86_RS01570	COG1286	toxin biosynthetic process
BVD86_RS01595	COG4783	chaperone-mediated protein folding
BVD86_RS01600	COG1610	YqeY-like protein
BVD86_RS01630	COG2815	serine threonine protein kinase
BVD86_RS01630	COG0515	serine threonine protein kinase
BVD86_RS01655	COG1278	Cold shock
BVD86_RS01670	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVD86_RS01675	COG0786	glutamate:sodium symporter activity
BVD86_RS01680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVD86_RS01680	COG0475	glutathione-regulated potassium exporter activity
BVD86_RS01705	COG2985	domain, Protein
BVD86_RS01715	COG2995	paraquat-inducible protein a
BVD86_RS01720	COG3008	intermembrane lipid transfer
BVD86_RS01720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVD86_RS01730	COG2351	hydroxyisourate hydrolase activity
BVD86_RS01770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVD86_RS01780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVD86_RS01785	COG0642	Histidine kinase
BVD86_RS01790	COG0745	RESPONSE REGULATOR receiver
BVD86_RS01805	COG1794	racemase activity, acting on amino acids and derivatives
BVD86_RS01815	COG2175	clavaminate synthase activity
BVD86_RS01820	COG3246	L-lysine catabolic process to acetate
BVD86_RS01825	COG2814	Major facilitator Superfamily
BVD86_RS01840	COG2855	membrane
BVD86_RS01885	COG1301	dicarboxylic acid transport
BVD86_RS01895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVD86_RS01900	COG2011	ABC-type metal ion transport system permease component
BVD86_RS01905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVD86_RS01915	COG0151	Belongs to the GarS family
BVD86_RS01925	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BVD86_RS01955	COG2308	Evidence 4 Homologs of previously reported genes of
BVD86_RS01965	COG1305	Transglutaminase-like
BVD86_RS01975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVD86_RS01980	COG0305	Participates in initiation and elongation during chromosome replication
BVD86_RS02005	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BVD86_RS02010	COG1845	cytochrome c oxidase, subunit III
BVD86_RS02015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVD86_RS02045	COG1649	PFAM Uncharacterised BCR, COG1649
BVD86_RS02045	COG0726	polysaccharide deacetylase
BVD86_RS02050	COG1215	transferase activity, transferring glycosyl groups
BVD86_RS02055	COG3658	cytochrome
BVD86_RS02065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS02080	COG0583	DNA-binding transcription factor activity
BVD86_RS02095	COG2890	protein-(glutamine-N5) methyltransferase activity
BVD86_RS02100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS02105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_RS02120	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS02125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS02140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVD86_RS02150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVD86_RS02155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVD86_RS02165	COG2205	protein histidine kinase activity
BVD86_RS02170	COG0745	RESPONSE REGULATOR receiver
BVD86_RS02175	COG0174	glutamine synthetase
BVD86_RS02190	COG0477	Major facilitator Superfamily
BVD86_RS02195	COG0729	surface antigen
BVD86_RS02230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVD86_RS02235	COG2814	Major facilitator Superfamily
BVD86_RS02245	COG0583	DNA-binding transcription factor activity
BVD86_RS02260	COG1187	pseudouridine synthase activity
BVD86_RS02280	COG0802	atpase or kinase
BVD86_RS02285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVD86_RS02295	COG1923	regulation of RNA biosynthetic process
BVD86_RS02300	COG0697	spore germination
BVD86_RS02325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVD86_RS02330	COG0519	Catalyzes the synthesis of GMP from XMP
BVD86_RS02330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVD86_RS02335	COG4302	ethanolamine ammonia-lyase activity
BVD86_RS02340	COG4303	Ethanolamine ammonia lyase large subunit
BVD86_RS02345	COG0531	amino acid
BVD86_RS02365	COG1454	alcohol dehydrogenase
BVD86_RS02370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVD86_RS02395	COG0308	aminopeptidase N
BVD86_RS02440	COG1605	Chorismate mutase
BVD86_RS02490	COG3772	lysozyme
BVD86_RS02500	COG1733	regulation of RNA biosynthetic process
BVD86_RS02525	COG0583	DNA-binding transcription factor activity
BVD86_RS02565	COG0488	(ABC) transporter
BVD86_RS02570	COG0589	response to stress
BVD86_RS02590	COG3135	benzoate transporter
BVD86_RS02595	COG1522	sequence-specific DNA binding
BVD86_RS02605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVD86_RS02610	COG0583	DNA-binding transcription factor activity
BVD86_RS02620	COG0183	Belongs to the thiolase family
BVD86_RS02630	COG2030	dehydratase
BVD86_RS02660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVD86_RS02670	COG0824	Thioesterase
BVD86_RS02675	COG1454	alcohol dehydrogenase
BVD86_RS02700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVD86_RS02730	COG0069	glutamate synthase activity
BVD86_RS02880	COG5410	chromosome segregation
BVD86_RS03085	COG2814	Major facilitator Superfamily
BVD86_RS03100	COG0511	ligase activity, forming carbon-carbon bonds
BVD86_RS03125	COG4264	IucA IucC family
BVD86_RS03135	COG4264	IucA IucC family
BVD86_RS03140	COG2423	ornithine cyclodeaminase activity
BVD86_RS03145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVD86_RS03155	COG1116	anion transmembrane transporter activity
BVD86_RS03155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_RS03170	COG2146	nitrite reductase [NAD(P)H] activity
BVD86_RS03170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_RS03175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_RS03180	COG0243	molybdopterin cofactor binding
BVD86_RS03190	COG0243	molybdopterin cofactor binding
BVD86_RS03195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVD86_RS03210	COG0315	cyclic pyranopterin monophosphate synthase activity
BVD86_RS03210	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVD86_RS03215	COG0303	'Molybdopterin
BVD86_RS03225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_RS03230	COG0697	spore germination
BVD86_RS03255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVD86_RS03320	COG2204	response regulator
BVD86_RS03325	COG3852	Histidine kinase
BVD86_RS03350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVD86_RS03355	COG0575	Belongs to the CDS family
BVD86_RS03370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVD86_RS03390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVD86_RS03405	COG2137	regulation of response to DNA damage stimulus
BVD86_RS03415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVD86_RS03420	COG1011	Hydrolase
BVD86_RS03435	COG1522	sequence-specific DNA binding
BVD86_RS03445	COG1113	amino acid transport
BVD86_RS03465	COG0659	secondary active sulfate transmembrane transporter activity
BVD86_RS03485	COG3300	MHYT domain
BVD86_RS03485	COG5001	Diguanylate cyclase
BVD86_RS03505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVD86_RS03505	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BVD86_RS03505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVD86_RS03510	COG1105	Belongs to the carbohydrate kinase PfkB family
BVD86_RS03515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD86_RS03515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVD86_RS03535	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BVD86_RS03545	COG0024	Methionine aminopeptidase
BVD86_RS03550	COG0583	DNA-binding transcription factor activity
BVD86_RS03560	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVD86_RS03565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVD86_RS03570	COG0517	IMP dehydrogenase activity
BVD86_RS03570	COG0516	GMP reductase activity
BVD86_RS03595	COG0552	protein localization to endoplasmic reticulum
BVD86_RS03620	COG4890	Cyd operon protein YbgT
BVD86_RS03625	COG1294	oxidase, subunit
BVD86_RS03640	COG1585	Membrane protein implicated in regulation of membrane protease activity
BVD86_RS03650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVD86_RS03655	COG4774	siderophore transport
BVD86_RS03670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVD86_RS03675	COG0569	domain protein
BVD86_RS03680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVD86_RS03710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVD86_RS03715	COG0542	response to heat
BVD86_RS03725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVD86_RS03740	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD86_RS03740	COG1902	pentaerythritol trinitrate reductase activity
BVD86_RS03780	COG0148	phosphopyruvate hydratase activity
BVD86_RS03785	COG2323	membrane
BVD86_RS03795	COG4773	Receptor
BVD86_RS03800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BVD86_RS03810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVD86_RS03815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVD86_RS03820	COG0183	Belongs to the thiolase family
BVD86_RS03825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVD86_RS03830	COG0596	Alpha beta hydrolase
BVD86_RS03835	COG2271	Major facilitator Superfamily
BVD86_RS03840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVD86_RS03845	COG3485	protocatechuate 3,4-dioxygenase
BVD86_RS03850	COG3485	protocatechuate 3,4-dioxygenase
BVD86_RS03855	COG0710	3-dehydroquinate dehydratase activity
BVD86_RS03860	COG3420	alginic acid biosynthetic process
BVD86_RS03865	COG3659	wide pore channel activity
BVD86_RS03870	COG4993	Dehydrogenase
BVD86_RS03880	COG2391	methyltransferase activity
BVD86_RS03895	COG1414	Transcriptional regulator
BVD86_RS03900	COG0583	DNA-binding transcription factor activity
BVD86_RS03905	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS03930	COG2814	Major facilitator Superfamily
BVD86_RS03940	COG0154	amidase activity
BVD86_RS03960	COG4638	Rieske (2fe-2S)
BVD86_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS03980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS03990	COG3733	amine oxidase
BVD86_RS04005	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS04010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVD86_RS04015	COG0183	Belongs to the thiolase family
BVD86_RS04020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVD86_RS04025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVD86_RS04035	COG4829	muconolactone delta-isomerase
BVD86_RS04040	COG4948	Mandelate Racemase Muconate Lactonizing
BVD86_RS04045	COG0583	DNA-binding transcription factor activity
BVD86_RS04060	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS04075	COG0753	catalase activity
BVD86_RS04090	COG3231	kanamycin kinase activity
BVD86_RS04105	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS04115	COG3829	transcription factor binding
BVD86_RS04140	COG1846	Transcriptional regulator
BVD86_RS04145	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD86_RS04145	COG1902	pentaerythritol trinitrate reductase activity
BVD86_RS04185	COG1309	transcriptional regulator
BVD86_RS04190	COG0583	DNA-binding transcription factor activity
BVD86_RS04195	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS04215	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS04225	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS04240	COG1309	transcriptional regulator
BVD86_RS04250	COG3956	TIGRFAM MazG family protein
BVD86_RS04285	COG0583	DNA-binding transcription factor activity
BVD86_RS04310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVD86_RS04315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVD86_RS04370	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS04375	COG0129	dihydroxy-acid dehydratase activity
BVD86_RS04385	COG0583	DNA-binding transcription factor activity
BVD86_RS04390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVD86_RS04400	COG2084	Dehydrogenase
BVD86_RS04405	COG2207	Transcriptional regulator
BVD86_RS04410	COG1064	alcohol dehydrogenase
BVD86_RS04425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVD86_RS04430	COG1120	ATPase activity
BVD86_RS04450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVD86_RS04520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVD86_RS04555	COG0084	hydrolase, TatD family'
BVD86_RS04575	COG1073	alpha beta
BVD86_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS04600	COG2207	Transcriptional regulator
BVD86_RS04615	COG4628	conserved protein (DUF2132)
BVD86_RS04630	COG0277	FAD linked oxidase domain protein
BVD86_RS04650	COG2271	Major facilitator Superfamily
BVD86_RS04680	COG1309	transcriptional regulator
BVD86_RS04690	COG2175	clavaminate synthase activity
BVD86_RS04695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVD86_RS04710	COG0667	Aldo Keto reductase
BVD86_RS04715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS04730	COG2175	clavaminate synthase activity
BVD86_RS04760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS04765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS04770	COG4771	TonB-dependent receptor
BVD86_RS04800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS04805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_RS04810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS04815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS04830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVD86_RS04835	COG0805	protein transport
BVD86_RS04845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS04865	COG1132	(ABC) transporter
BVD86_RS04870	COG1132	(ABC) transporter
BVD86_RS04890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVD86_RS04895	COG0601	transmembrane transport
BVD86_RS04925	COG3539	Fimbrial protein
BVD86_RS04950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BVD86_RS04960	COG0753	catalase activity
BVD86_RS04980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVD86_RS04990	COG2205	protein histidine kinase activity
BVD86_RS04995	COG0745	RESPONSE REGULATOR receiver
BVD86_RS05000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS05005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVD86_RS05060	COG3433	isochorismatase activity
BVD86_RS05060	COG1535	isochorismatase
BVD86_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS05070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BVD86_RS05075	COG4149	molybdate abc transporter
BVD86_RS05080	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVD86_RS05090	COG4638	Rieske (2fe-2S)
BVD86_RS05095	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BVD86_RS05100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_RS05100	COG0543	2 iron, 2 sulfur cluster binding
BVD86_RS05115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS05145	COG2207	Transcriptional regulator
BVD86_RS05150	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS05155	COG2610	gluconate transmembrane transporter activity
BVD86_RS05180	COG0583	DNA-binding transcription factor activity
BVD86_RS05195	COG2031	fatty acid transporter
BVD86_RS05200	COG0183	Belongs to the thiolase family
BVD86_RS05205	COG0583	DNA-binding transcription factor activity
BVD86_RS05210	COG0583	DNA-binding transcription factor activity
BVD86_RS05225	COG1027	Aspartate ammonia-lyase
BVD86_RS05235	COG0477	Major facilitator Superfamily
BVD86_RS05255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS05260	COG4521	taurine ABC transporter
BVD86_RS05275	COG2188	Transcriptional regulator
BVD86_RS05285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVD86_RS05290	COG1733	regulation of RNA biosynthetic process
BVD86_RS05295	COG2207	Transcriptional regulator
BVD86_RS05295	COG3708	Transcriptional regulator
BVD86_RS05310	COG0730	response to heat
BVD86_RS05330	COG3781	membrane
BVD86_RS05335	COG1063	alcohol dehydrogenase
BVD86_RS05345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_RS05350	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVD86_RS05355	COG0022	dehydrogenase e1 component
BVD86_RS05360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVD86_RS05365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVD86_RS05380	COG3706	GGDEF domain
BVD86_RS05400	COG0133	tryptophan synthase activity
BVD86_RS05410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVD86_RS05440	COG0583	DNA-binding transcription factor activity
BVD86_RS05445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVD86_RS05455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVD86_RS05515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVD86_RS05520	COG4773	Receptor
BVD86_RS05545	COG0730	response to heat
BVD86_RS05550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVD86_RS05570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BVD86_RS05600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVD86_RS05615	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS05620	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS05625	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVD86_RS05630	COG2207	Transcriptional regulator
BVD86_RS05635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVD86_RS05640	COG0776	regulation of translation
BVD86_RS05665	COG0822	iron-sulfur transferase activity
BVD86_RS05670	COG0316	Belongs to the HesB IscA family
BVD86_RS05700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVD86_RS05720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVD86_RS05725	COG0702	epimerase
BVD86_RS05765	COG0601	transmembrane transport
BVD86_RS05775	COG4166	transmembrane transport
BVD86_RS05820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BVD86_RS05825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVD86_RS05840	COG2431	L-lysine efflux transmembrane transporter activity
BVD86_RS05855	COG0776	regulation of translation
BVD86_RS05920	COG0084	hydrolase, TatD family'
BVD86_RS05940	COG1663	tetraacyldisaccharide 4'-kinase activity
BVD86_RS05945	COG1132	(ABC) transporter
BVD86_RS05955	COG0811	peptide transport
BVD86_RS05960	COG1475	DNA binding
BVD86_RS05965	COG1192	Involved in chromosome partitioning
BVD86_RS05975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVD86_RS05980	COG3178	'Phosphotransferase
BVD86_RS05990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVD86_RS06015	COG0424	maF-like protein
BVD86_RS06020	COG2850	peptidyl-arginine hydroxylation
BVD86_RS06030	COG0640	Transcriptional regulator
BVD86_RS06040	COG3619	membrane
BVD86_RS06045	COG3122	Protein conserved in bacteria
BVD86_RS06055	COG1132	(ABC) transporter
BVD86_RS06075	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVD86_RS06080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVD86_RS06090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVD86_RS06090	COG0506	proline dehydrogenase activity
BVD86_RS06090	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVD86_RS06095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BVD86_RS06110	COG3698	Phosphodiester glycosidase
BVD86_RS06120	COG2353	YceI-like domain
BVD86_RS06130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVD86_RS06175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVD86_RS06175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVD86_RS06200	COG3539	Fimbrial protein
BVD86_RS06225	COG0583	DNA-binding transcription factor activity
BVD86_RS06230	COG0697	spore germination
BVD86_RS06240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVD86_RS06250	COG0583	DNA-binding transcription factor activity
BVD86_RS06265	COG1309	transcriptional regulator
BVD86_RS06280	COG1522	sequence-specific DNA binding
BVD86_RS06290	COG1126	abc transporter atp-binding protein
BVD86_RS06295	COG0765	amino acid transport
BVD86_RS06300	COG0765	amino acid transport
BVD86_RS06330	COG1464	Belongs to the NlpA lipoprotein family
BVD86_RS06340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVD86_RS06345	COG2011	ABC-type metal ion transport system permease component
BVD86_RS06350	COG0012	GTP binding
BVD86_RS06375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BVD86_RS06410	COG1917	Cupin 2, conserved barrel domain protein
BVD86_RS06410	COG2207	Transcriptional regulator
BVD86_RS06415	COG0386	Belongs to the glutathione peroxidase family
BVD86_RS06425	COG0436	Aminotransferase
BVD86_RS06430	COG1301	dicarboxylic acid transport
BVD86_RS06465	COG3634	alkyl hydroperoxide reductase activity
BVD86_RS06480	COG0583	DNA-binding transcription factor activity
BVD86_RS06485	COG0798	PFAM Bile acid sodium symporter
BVD86_RS06490	COG0640	Transcriptional regulator
BVD86_RS06505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BVD86_RS06515	COG0583	DNA-binding transcription factor activity
BVD86_RS06525	COG1953	Uracil, thiamine, allantoin
BVD86_RS06535	COG2175	clavaminate synthase activity
BVD86_RS06540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS06545	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BVD86_RS06550	COG4521	taurine ABC transporter
BVD86_RS06560	COG0477	Major facilitator Superfamily
BVD86_RS06585	COG1271	oxidase subunit
BVD86_RS06590	COG1294	oxidase, subunit
BVD86_RS06600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_RS06620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVD86_RS06640	COG3052	prosthetic group binding
BVD86_RS06645	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BVD86_RS06655	COG2814	Major facilitator Superfamily
BVD86_RS06675	COG1346	cytolysis
BVD86_RS06685	COG0583	DNA-binding transcription factor activity
BVD86_RS06690	COG0625	glutathione transferase activity
BVD86_RS06695	COG0625	glutathione transferase activity
BVD86_RS06715	COG0583	DNA-binding transcription factor activity
BVD86_RS06730	COG1045	serine acetyltransferase
BVD86_RS06735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVD86_RS06740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVD86_RS06750	COG1280	lysine exporter protein (LysE YggA)
BVD86_RS06760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_RS06765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_RS06775	COG0765	amino acid transport
BVD86_RS06780	COG0765	amino acid transport
BVD86_RS06820	COG2205	protein histidine kinase activity
BVD86_RS06820	COG0784	Response regulator, receiver
BVD86_RS06840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BVD86_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS06905	COG0583	DNA-binding transcription factor activity
BVD86_RS06920	COG2814	Major facilitator Superfamily
BVD86_RS06935	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS06940	COG1309	transcriptional regulator
BVD86_RS06945	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS06950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVD86_RS06955	COG1024	Enoyl-CoA hydratase
BVD86_RS06960	COG4770	biotin carboxylase activity
BVD86_RS06970	COG0583	DNA-binding transcription factor activity
BVD86_RS06985	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS06995	COG2814	Major facilitator Superfamily
BVD86_RS07005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVD86_RS07010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVD86_RS07015	COG2814	Major facilitator Superfamily
BVD86_RS07020	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS07025	COG1024	Enoyl-CoA hydratase
BVD86_RS07035	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVD86_RS07040	COG0183	Belongs to the thiolase family
BVD86_RS07050	COG2814	Major facilitator Superfamily
BVD86_RS07060	COG1024	Enoyl-CoA hydratase
BVD86_RS07075	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS07080	COG2814	Major facilitator Superfamily
BVD86_RS07085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVD86_RS07090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVD86_RS07105	COG3842	ATPase activity
BVD86_RS07110	COG1840	ABC-type Fe3 transport system, periplasmic component
BVD86_RS07125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_RS07130	COG1414	Transcriptional regulator
BVD86_RS07140	COG0583	DNA-binding transcription factor activity
BVD86_RS07145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVD86_RS07150	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS07160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVD86_RS07170	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS07175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS07180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS07185	COG2267	carboxylic ester hydrolase activity
BVD86_RS07215	COG2271	Major facilitator Superfamily
BVD86_RS07220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVD86_RS07225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVD86_RS07270	COG2050	protein possibly involved in aromatic compounds catabolism
BVD86_RS07280	COG3327	negative regulation of DNA-templated transcription, initiation
BVD86_RS07285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BVD86_RS07290	COG0183	Belongs to the thiolase family
BVD86_RS07295	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVD86_RS07300	COG1024	Enoyl-CoA hydratase
BVD86_RS07305	COG1024	Enoyl-CoA hydratase
BVD86_RS07310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_RS07315	COG2151	metal-sulfur cluster biosynthetic enzyme
BVD86_RS07320	COG3396	Phenylacetate-CoA oxygenase
BVD86_RS07325	COG3460	Phenylacetate-CoA oxygenase
BVD86_RS07330	COG3396	Phenylacetate-CoA oxygenase
BVD86_RS07335	COG2030	dehydratase
BVD86_RS07335	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS07340	COG1760	l-serine dehydratase
BVD86_RS07345	COG0531	amino acid
BVD86_RS07350	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS07375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVD86_RS07395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_RS07410	COG0789	Transcriptional regulator
BVD86_RS07420	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVD86_RS07425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_RS07440	COG2807	transmembrane transport
BVD86_RS07445	COG0590	tRNA wobble adenosine to inosine editing
BVD86_RS07495	COG2885	chlorophyll binding
BVD86_RS07550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVD86_RS07580	COG3209	COG3209 Rhs family protein
BVD86_RS07580	COG4104	PAAR repeat-containing protein
BVD86_RS07595	COG0477	Major facilitator Superfamily
BVD86_RS07610	COG1116	anion transmembrane transporter activity
BVD86_RS07625	COG0864	Transcriptional regulator
BVD86_RS07635	COG1733	regulation of RNA biosynthetic process
BVD86_RS07640	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_RS07645	COG0439	Biotin carboxylase
BVD86_RS07660	COG1063	alcohol dehydrogenase
BVD86_RS07665	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVD86_RS07695	COG0038	chloride channel
BVD86_RS07700	COG4770	biotin carboxylase activity
BVD86_RS07720	COG1914	H( )-stimulated, divalent metal cation uptake system
BVD86_RS07725	COG0583	DNA-binding transcription factor activity
BVD86_RS07735	COG1595	DNA-templated transcription, initiation
BVD86_RS07745	COG3220	belongs to the UPF0276 family
BVD86_RS07810	COG1309	transcriptional regulator
BVD86_RS07825	COG0657	acetylesterase activity
BVD86_RS07865	COG3038	cytochrome b561
BVD86_RS07870	COG0753	catalase activity
BVD86_RS07875	COG1733	regulation of RNA biosynthetic process
BVD86_RS07900	COG1278	Cold shock
BVD86_RS07935	COG1522	sequence-specific DNA binding
BVD86_RS07940	COG0531	amino acid
BVD86_RS07945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVD86_RS07960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVD86_RS07975	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BVD86_RS07985	COG4122	O-methyltransferase activity
BVD86_RS08015	COG1538	Outer membrane efflux protein
BVD86_RS08020	COG1137	ATPase activity
BVD86_RS08025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVD86_RS08035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BVD86_RS08085	COG2814	Major facilitator Superfamily
BVD86_RS08095	COG0668	transmembrane transport
BVD86_RS08140	COG1309	transcriptional regulator
BVD86_RS08170	COG2226	methyltransferase
BVD86_RS08175	COG1011	Hydrolase
BVD86_RS08200	COG1278	Cold shock
BVD86_RS08205	COG1560	Kdo2-lipid A biosynthetic process
BVD86_RS08210	COG1280	lysine exporter protein (LysE YggA)
BVD86_RS08245	COG1570	exodeoxyribonuclease VII activity
BVD86_RS08330	COG2871	sodium ion transport
BVD86_RS08340	COG0583	DNA-binding transcription factor activity
BVD86_RS08350	COG4638	Rieske (2fe-2S)
BVD86_RS08355	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BVD86_RS08360	COG0543	2 iron, 2 sulfur cluster binding
BVD86_RS08360	COG0633	Ferredoxin
BVD86_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS08370	COG3135	benzoate transporter
BVD86_RS08375	COG2814	Major facilitator Superfamily
BVD86_RS08390	COG1643	Atp-dependent helicase
BVD86_RS08415	COG3634	alkyl hydroperoxide reductase activity
BVD86_RS08435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVD86_RS08445	COG0625	glutathione transferase activity
BVD86_RS08455	COG2885	chlorophyll binding
BVD86_RS08490	COG0542	response to heat
BVD86_RS08505	COG1765	OsmC-like protein
BVD86_RS08520	COG0667	Aldo Keto reductase
BVD86_RS08535	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVD86_RS08555	COG0527	aspartate kinase activity
BVD86_RS08565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVD86_RS08575	COG3038	cytochrome b561
BVD86_RS08580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BVD86_RS08585	COG2252	PERMEase
BVD86_RS08595	COG1741	Belongs to the pirin family
BVD86_RS08600	COG1309	transcriptional regulator
BVD86_RS08615	COG2072	flavoprotein involved in K transport
BVD86_RS08620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BVD86_RS08625	COG0583	DNA-binding transcription factor activity
BVD86_RS08640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BVD86_RS08670	COG1944	ATP diphosphatase activity
BVD86_RS08690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVD86_RS08705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_RS08725	COG2814	Major facilitator Superfamily
BVD86_RS08730	COG1024	Enoyl-CoA hydratase
BVD86_RS08735	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS08745	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS08770	COG0697	spore germination
BVD86_RS08800	COG4968	Prepilin-type N-terminal cleavage methylation domain
BVD86_RS08810	COG4796	Type ii and iii secretion system protein
BVD86_RS08835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVD86_RS08845	COG2165	general secretion pathway protein
BVD86_RS08890	COG1113	amino acid transport
BVD86_RS08910	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS08930	COG0531	amino acid
BVD86_RS08940	COG1113	amino acid transport
BVD86_RS08970	COG3209	COG3209 Rhs family protein
BVD86_RS08985	COG4269	membrane
BVD86_RS09000	COG0582	viral genome integration into host DNA
BVD86_RS09015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_RS09055	COG2801	Transposase and inactivated derivatives
BVD86_RS09080	COG0583	DNA-binding transcription factor activity
BVD86_RS09100	COG0235	Class ii aldolase
BVD86_RS09105	COG0477	Major facilitator Superfamily
BVD86_RS09115	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS09125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVD86_RS09130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD86_RS09135	COG1113	amino acid transport
BVD86_RS09145	COG1522	sequence-specific DNA binding
BVD86_RS09170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BVD86_RS09180	COG2207	Transcriptional regulator
BVD86_RS09210	COG1309	transcriptional regulator
BVD86_RS09225	COG0210	DNA helicase
BVD86_RS09320	COG1113	amino acid transport
BVD86_RS09340	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BVD86_RS09340	COG2508	Transcriptional regulator
BVD86_RS09355	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD86_RS09355	COG1902	pentaerythritol trinitrate reductase activity
BVD86_RS09365	COG2203	Gaf domain
BVD86_RS09365	COG4251	negative regulation of phosphorylation
BVD86_RS09365	COG5001	Diguanylate cyclase
BVD86_RS09365	COG3706	GGDEF domain
BVD86_RS09375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVD86_RS09395	COG4172	Belongs to the ABC transporter superfamily
BVD86_RS09400	COG4239	(ABC) transporter, permease
BVD86_RS09405	COG4174	ABC transporter (Permease)
BVD86_RS09410	COG4166	transmembrane transport
BVD86_RS09415	COG1388	LysM domain
BVD86_RS09415	COG0741	lytic transglycosylase activity
BVD86_RS09415	COG0741	lytic transglycosylase activity
BVD86_RS09415	COG1388	LysM domain
BVD86_RS09455	COG0583	DNA-binding transcription factor activity
BVD86_RS09460	COG1279	arginine transmembrane transporter activity
BVD86_RS09470	COG0789	Transcriptional regulator
BVD86_RS09480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_RS09485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_RS09490	COG0006	proline dipeptidase activity
BVD86_RS09825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVD86_RS09840	COG3384	dioxygenase
BVD86_RS09850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD86_RS09855	COG2878	Part of a membrane complex involved in electron transport
BVD86_RS09860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVD86_RS09885	COG0768	penicillin binding
BVD86_RS09890	COG0742	ribosomal rna small subunit methyltransferase
BVD86_RS09905	COG0830	nickel cation binding
BVD86_RS09915	COG0804	urea catabolic process
BVD86_RS09940	COG3015	lipoprotein NlpE involved in copper resistance
BVD86_RS09955	COG1253	flavin adenine dinucleotide binding
BVD86_RS09960	COG2851	Citrate transporter
BVD86_RS10010	COG1773	rubredoxin
BVD86_RS10015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_RS10020	COG2267	carboxylic ester hydrolase activity
BVD86_RS10025	COG0583	DNA-binding transcription factor activity
BVD86_RS10055	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BVD86_RS10060	COG4181	ATPase activity
BVD86_RS10105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVD86_RS10125	COG0306	phosphate transporter
BVD86_RS10140	COG3958	Transketolase
BVD86_RS10145	COG3959	Transketolase, thiamine diphosphate binding domain
BVD86_RS10150	COG2271	Major facilitator Superfamily
BVD86_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS10160	COG0583	DNA-binding transcription factor activity
BVD86_RS10180	COG2223	nitrite transmembrane transporter activity
BVD86_RS10185	COG2207	Transcriptional regulator
BVD86_RS10190	COG2066	Belongs to the glutaminase family
BVD86_RS10195	COG0242	peptide deformylase activity
BVD86_RS10200	COG0477	Major facilitator Superfamily
BVD86_RS10210	COG0028	Belongs to the TPP enzyme family
BVD86_RS10225	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS10230	COG2267	carboxylic ester hydrolase activity
BVD86_RS10240	COG2271	Major facilitator Superfamily
BVD86_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS10275	COG1414	Transcriptional regulator
BVD86_RS10300	COG1215	transferase activity, transferring glycosyl groups
BVD86_RS10305	COG1649	PFAM Uncharacterised BCR, COG1649
BVD86_RS10305	COG0726	polysaccharide deacetylase
BVD86_RS10315	COG4681	YaeQ
BVD86_RS10325	COG0523	cobalamin synthesis protein
BVD86_RS10335	COG1607	acyl-coa hydrolase
BVD86_RS10345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVD86_RS10350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVD86_RS10355	COG1309	transcriptional regulator
BVD86_RS10380	COG2040	homocysteine
BVD86_RS10385	COG0531	amino acid
BVD86_RS10440	COG1595	DNA-templated transcription, initiation
BVD86_RS10450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_RS10455	COG0477	Major facilitator Superfamily
BVD86_RS10500	COG0405	Gamma-glutamyltransferase
BVD86_RS10505	COG2814	Major facilitator Superfamily
BVD86_RS10515	COG2050	protein possibly involved in aromatic compounds catabolism
BVD86_RS10530	COG1090	epimerase
BVD86_RS10550	COG0420	3'-5' exonuclease activity
BVD86_RS10575	COG0735	belongs to the Fur family
BVD86_RS10580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVD86_RS10585	COG2914	Belongs to the UPF0125 (RnfH) family
BVD86_RS10605	COG0121	glutamine amidotransferase
BVD86_RS10620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVD86_RS10630	COG0210	DNA helicase
BVD86_RS10635	COG2885	chlorophyll binding
BVD86_RS10640	COG0204	Acyl-transferase
BVD86_RS10655	COG2894	cell division
BVD86_RS10670	COG1280	lysine exporter protein (LysE YggA)
BVD86_RS10675	COG1674	ftsk spoiiie
BVD86_RS10680	COG0492	ferredoxin-NADP+ reductase activity
BVD86_RS10685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVD86_RS10695	COG0456	acetyltransferase
BVD86_RS10710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVD86_RS10715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVD86_RS10725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVD86_RS10740	COG1981	membrane
BVD86_RS10750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVD86_RS10750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVD86_RS10770	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS10775	COG4638	Rieske (2fe-2S)
BVD86_RS10780	COG0657	acetylesterase activity
BVD86_RS10790	COG0473	3-isopropylmalate dehydrogenase activity
BVD86_RS10795	COG0583	DNA-binding transcription factor activity
BVD86_RS10815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVD86_RS10855	COG0358	DNA primase activity
BVD86_RS10875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BVD86_RS10905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVD86_RS10935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVD86_RS10945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVD86_RS10945	COG0352	thiamine-phosphate diphosphorylase activity
BVD86_RS10945	COG0351	phosphomethylpyrimidine kinase
BVD86_RS10950	COG1652	LysM domain
BVD86_RS10975	COG1399	metal-binding, possibly nucleic acid-binding protein
BVD86_RS10980	COG3101	peptidyl-lysine hydroxylation
BVD86_RS10985	COG0009	L-threonylcarbamoyladenylate synthase
BVD86_RS10990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BVD86_RS10995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVD86_RS11020	COG4106	trans-aconitate 2-methyltransferase activity
BVD86_RS11035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVD86_RS11035	COG0596	Alpha beta hydrolase
BVD86_RS11035	COG2226	methyltransferase
BVD86_RS11045	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BVD86_RS11050	COG2223	nitrite transmembrane transporter activity
BVD86_RS11070	COG1196	nuclear chromosome segregation
BVD86_RS11080	COG0730	response to heat
BVD86_RS11095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVD86_RS11105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVD86_RS11155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVD86_RS11160	COG0489	protein tyrosine kinase activity
BVD86_RS11170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD86_RS11170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD86_RS11205	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BVD86_RS11210	COG2081	HI0933 family
BVD86_RS11220	COG0668	transmembrane transport
BVD86_RS11240	COG0583	DNA-binding transcription factor activity
BVD86_RS11260	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVD86_RS11265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVD86_RS11295	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BVD86_RS11320	COG2199	diguanylate cyclase activity
BVD86_RS11335	COG0745	RESPONSE REGULATOR receiver
BVD86_RS11350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVD86_RS11410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS11425	COG0583	DNA-binding transcription factor activity
BVD86_RS11480	COG0583	DNA-binding transcription factor activity
BVD86_RS11500	COG0583	DNA-binding transcription factor activity
BVD86_RS11505	COG1053	succinate dehydrogenase
BVD86_RS11520	COG1309	transcriptional regulator
BVD86_RS11530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVD86_RS11535	COG2814	Major facilitator Superfamily
BVD86_RS11540	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS11545	COG0583	DNA-binding transcription factor activity
BVD86_RS11550	COG1063	alcohol dehydrogenase
BVD86_RS11580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVD86_RS11585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVD86_RS11590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVD86_RS11610	COG2132	Multicopper oxidase
BVD86_RS11620	COG0561	phosphatase activity
BVD86_RS11625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVD86_RS11635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BVD86_RS11650	COG1214	PFAM Peptidase M22, glycoprotease
BVD86_RS11710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVD86_RS11715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVD86_RS11720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVD86_RS11780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVD86_RS11790	COG1846	Transcriptional regulator
BVD86_RS11795	COG1764	response to oxidative stress
BVD86_RS11820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVD86_RS11820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVD86_RS11835	COG0037	tRNA processing
BVD86_RS11845	COG0248	Ppx GppA phosphatase
BVD86_RS11875	COG0072	phenylalanine-tRNA ligase activity
BVD86_RS11905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BVD86_RS11920	COG1238	metal cluster binding
BVD86_RS11925	COG0625	glutathione transferase activity
BVD86_RS11945	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS11950	COG3028	Belongs to the UPF0307 family
BVD86_RS11955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD86_RS11975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVD86_RS11980	COG0617	tRNA 3'-terminal CCA addition
BVD86_RS11985	COG1555	photosystem II stabilization
BVD86_RS11990	COG3956	TIGRFAM MazG family protein
BVD86_RS11995	COG4221	oxidoreductase activity
BVD86_RS12000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVD86_RS12015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVD86_RS12020	COG5002	protein histidine kinase activity
BVD86_RS12020	COG2205	protein histidine kinase activity
BVD86_RS12020	COG0784	Response regulator, receiver
BVD86_RS12025	COG1024	Enoyl-CoA hydratase
BVD86_RS12030	COG2084	Dehydrogenase
BVD86_RS12035	COG3622	Belongs to the hyi family
BVD86_RS12070	COG0697	spore germination
BVD86_RS12080	COG2814	Major facilitator Superfamily
BVD86_RS12085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVD86_RS12100	COG0583	DNA-binding transcription factor activity
BVD86_RS12110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVD86_RS12120	COG0084	hydrolase, TatD family'
BVD86_RS12135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVD86_RS12155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVD86_RS12160	COG0440	acetolactate synthase activity
BVD86_RS12165	COG0028	Belongs to the TPP enzyme family
BVD86_RS12185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS12190	COG1136	(ABC) transporter
BVD86_RS12190	COG0577	efflux transmembrane transporter activity
BVD86_RS12210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BVD86_RS12215	COG1162	GTPase activity
BVD86_RS12225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVD86_RS12245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVD86_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS12290	COG2986	histidine ammonia-lyase
BVD86_RS12305	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS12315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVD86_RS12340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVD86_RS12360	COG1426	Protein conserved in bacteria
BVD86_RS12395	COG0793	Belongs to the peptidase S41A family
BVD86_RS12410	COG2267	carboxylic ester hydrolase activity
BVD86_RS12420	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS12425	COG3265	gluconokinase activity
BVD86_RS12435	COG0800	Aldolase
BVD86_RS12450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVD86_RS12455	COG0280	phosphate acetyltransferase
BVD86_RS12455	COG0857	belongs to the CobB CobQ family
BVD86_RS12460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BVD86_RS12460	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BVD86_RS12480	COG0740	serine-type endopeptidase activity
BVD86_RS12490	COG4774	siderophore transport
BVD86_RS12500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVD86_RS12510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVD86_RS12510	COG2813	Specifically methylates the guanine in position
BVD86_RS12610	COG0788	formyltetrahydrofolate deformylase activity
BVD86_RS12635	COG4651	solute:proton antiporter activity
BVD86_RS12635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVD86_RS12655	COG0724	RNA recognition motif
BVD86_RS12660	COG0210	DNA helicase
BVD86_RS12685	COG1733	regulation of RNA biosynthetic process
BVD86_RS12695	COG2900	Belongs to the SlyX family
BVD86_RS12700	COG0488	(ABC) transporter
BVD86_RS12710	COG1560	Kdo2-lipid A biosynthetic process
BVD86_RS12720	COG1301	dicarboxylic acid transport
BVD86_RS12775	COG0473	3-isopropylmalate dehydrogenase activity
BVD86_RS12800	COG0583	DNA-binding transcription factor activity
BVD86_RS12845	COG0583	DNA-binding transcription factor activity
BVD86_RS12855	COG0625	glutathione transferase activity
BVD86_RS12860	COG2378	regulation of single-species biofilm formation
BVD86_RS12865	COG0546	phosphoglycolate phosphatase activity
BVD86_RS12880	COG1530	ribonuclease E activity
BVD86_RS12885	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS12900	COG0583	DNA-binding transcription factor activity
BVD86_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS12910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVD86_RS12920	COG0534	Mate efflux family protein
BVD86_RS12935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVD86_RS12965	COG0493	'glutamate synthase
BVD86_RS12965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVD86_RS12975	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BVD86_RS12980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVD86_RS12995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVD86_RS13005	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BVD86_RS13005	COG0644	oxidoreductase
BVD86_RS13015	COG4535	Mg2 and Co2 transporter CorC
BVD86_RS13025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD86_RS13045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVD86_RS13055	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BVD86_RS13065	COG0484	heat shock protein binding
BVD86_RS13070	COG0789	Transcriptional regulator
BVD86_RS13075	COG0598	Magnesium transport protein CorA
BVD86_RS13080	COG1185	polyribonucleotide nucleotidyltransferase activity
BVD86_RS13090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVD86_RS13095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVD86_RS13100	COG1074	ATP-dependent DNA helicase activity
BVD86_RS13105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BVD86_RS13125	COG2226	methyltransferase
BVD86_RS13150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVD86_RS13165	COG2111	Na H antiporter
BVD86_RS13165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVD86_RS13170	COG1006	Multisubunit Na H antiporter MnhC subunit
BVD86_RS13175	COG0651	ATP synthesis coupled electron transport
BVD86_RS13180	COG1863	multisubunit Na H antiporter MnhE subunit
BVD86_RS13185	COG2212	antiporter activity
BVD86_RS13190	COG1320	monovalent cation:proton antiporter activity
BVD86_RS13195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVD86_RS13205	COG0195	Participates in both transcription termination and antitermination
BVD86_RS13255	COG0237	dephospho-CoA kinase activity
BVD86_RS13265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVD86_RS13280	COG0497	DNA recombination
BVD86_RS13290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVD86_RS13325	COG2169	Transcriptional regulator
BVD86_RS13325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVD86_RS13330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVD86_RS13390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BVD86_RS13405	COG0326	Molecular chaperone. Has ATPase activity
BVD86_RS13420	COG2056	Na+-H+ antiporter family
BVD86_RS13490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVD86_RS13520	COG0546	phosphoglycolate phosphatase activity
BVD86_RS13525	COG1716	ATPase activity
BVD86_RS13570	COG0181	hydroxymethylbilane synthase activity
BVD86_RS13580	COG3275	phosphorelay sensor kinase activity
BVD86_RS13600	COG1538	Outer membrane efflux protein
BVD86_RS13610	COG0697	spore germination
BVD86_RS13635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVD86_RS13640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVD86_RS13645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVD86_RS13650	COG0772	Belongs to the SEDS family
BVD86_RS13675	COG4974	Belongs to the 'phage' integrase family
BVD86_RS13680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVD86_RS13690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BVD86_RS13700	COG2197	response regulator
BVD86_RS13715	COG0793	Belongs to the peptidase S41A family
BVD86_RS13720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BVD86_RS13725	COG0795	lipopolysaccharide-transporting ATPase activity
BVD86_RS13765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVD86_RS13765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVD86_RS13775	COG0004	ammonium transporteR
BVD86_RS13780	COG0347	Belongs to the P(II) protein family
BVD86_RS13790	COG0606	chelatase, subunit chli
BVD86_RS13795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_RS13800	COG0235	Class ii aldolase
BVD86_RS13805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_RS13825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVD86_RS13840	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS13850	COG0477	Major facilitator Superfamily
BVD86_RS13855	COG2860	membrane
BVD86_RS13865	COG1253	flavin adenine dinucleotide binding
BVD86_RS13875	COG2814	Major facilitator Superfamily
BVD86_RS13885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVD86_RS13925	COG0655	NAD(P)H dehydrogenase (quinone) activity
BVD86_RS13940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVD86_RS13970	COG1309	transcriptional regulator
BVD86_RS14005	COG0758	DNA mediated transformation
BVD86_RS14015	COG0697	spore germination
BVD86_RS14020	COG1309	transcriptional regulator
BVD86_RS14035	COG0386	Belongs to the glutathione peroxidase family
BVD86_RS14050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVD86_RS14060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVD86_RS14100	COG1121	(ABC) transporter
BVD86_RS14105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVD86_RS14110	COG1280	lysine exporter protein (LysE YggA)
BVD86_RS14115	COG2837	iron assimilation
BVD86_RS14120	COG0281	malic enzyme
BVD86_RS14165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVD86_RS14170	COG0519	Catalyzes the synthesis of GMP from XMP
BVD86_RS14170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVD86_RS14175	COG4399	Belongs to the UPF0754 family
BVD86_RS14180	COG2259	Doxx family
BVD86_RS14185	COG0586	Pfam SNARE associated Golgi protein
BVD86_RS14200	COG1192	Involved in chromosome partitioning
BVD86_RS14210	COG0271	Belongs to the BolA IbaG family
BVD86_RS14250	COG3321	synthase
BVD86_RS14250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVD86_RS14250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVD86_RS14250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVD86_RS14255	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS14260	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_RS14265	COG2197	response regulator
BVD86_RS14275	COG3916	Acyl-homoserine-lactone synthase
BVD86_RS14280	COG0477	Major facilitator Superfamily
BVD86_RS14285	COG1024	Enoyl-CoA hydratase
BVD86_RS14290	COG1024	Enoyl-CoA hydratase
BVD86_RS14295	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS14300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVD86_RS14320	COG1113	amino acid transport
BVD86_RS14325	COG1113	amino acid transport
BVD86_RS14330	COG0251	oxidation-reduction process
BVD86_RS14370	COG0564	pseudouridine synthase activity
BVD86_RS14415	COG1051	belongs to the nudix hydrolase family
BVD86_RS14435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVD86_RS14450	COG1802	Transcriptional regulator
BVD86_RS14460	COG1448	Aminotransferase
BVD86_RS14465	COG0277	FAD linked oxidase domain protein
BVD86_RS14475	COG2186	Transcriptional regulator
BVD86_RS14485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVD86_RS14490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVD86_RS14505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVD86_RS14515	COG0110	maltose O-acetyltransferase activity
BVD86_RS14535	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVD86_RS14570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVD86_RS14575	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVD86_RS14580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVD86_RS14585	COG1596	polysaccharide export
BVD86_RS14610	COG0728	peptidoglycan biosynthetic process
BVD86_RS14615	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVD86_RS14675	COG0546	phosphoglycolate phosphatase activity
BVD86_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS14695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVD86_RS14695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BVD86_RS14700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_RS14705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_RS14710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS14715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_RS14720	COG1116	anion transmembrane transporter activity
BVD86_RS14725	COG1309	transcriptional regulator
BVD86_RS14730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVD86_RS14740	COG0196	riboflavin kinase activity
BVD86_RS14745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVD86_RS14755	COG1047	Peptidyl-prolyl cis-trans
BVD86_RS14795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVD86_RS14800	COG0657	acetylesterase activity
BVD86_RS14860	COG2951	lytic endotransglycosylase activity
BVD86_RS14865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVD86_RS14880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVD86_RS14890	COG0671	phosphoesterase, PA-phosphatase related
BVD86_RS14895	COG0861	Integral membrane protein TerC family
BVD86_RS14905	COG0754	glutathionylspermidine amidase activity
BVD86_RS14915	COG0402	S-adenosylhomocysteine deaminase activity
BVD86_RS14930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVD86_RS14935	COG1230	cation diffusion facilitator family transporter
BVD86_RS14950	COG0706	membrane insertase activity
BVD86_RS14975	COG0592	DNA-directed DNA polymerase activity
BVD86_RS14985	COG0187	DNA topoisomerase II activity
BVD86_RS15000	COG0488	(ABC) transporter
BVD86_RS15025	COG0596	Alpha beta hydrolase
BVD86_RS15030	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BVD86_RS15035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVD86_RS15070	COG0625	glutathione transferase activity
BVD86_RS15080	COG0733	neurotransmitter:sodium symporter activity
BVD86_RS15120	COG2233	PERMEase
BVD86_RS15135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS15170	COG2814	Major facilitator Superfamily
BVD86_RS15175	COG0656	L-ascorbic acid biosynthetic process
BVD86_RS15180	COG0583	DNA-binding transcription factor activity
BVD86_RS15195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_RS15200	COG1064	alcohol dehydrogenase
BVD86_RS15205	COG2818	Glycosylase
BVD86_RS15220	COG1194	a g-specific adenine glycosylase
BVD86_RS15235	COG5487	UPF0391 membrane protein
BVD86_RS15240	COG2983	Belongs to the UPF0260 family
BVD86_RS15245	COG2133	pyrroloquinoline quinone binding
BVD86_RS15250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVD86_RS15255	COG2116	formate transmembrane transporter activity
BVD86_RS15275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_RS15280	COG1335	isochorismatase
BVD86_RS15285	COG0385	Bile acid
BVD86_RS15290	COG0534	Mate efflux family protein
BVD86_RS15295	COG1683	Conserved Protein
BVD86_RS15310	COG0346	lactoylglutathione lyase activity
BVD86_RS15315	COG0625	glutathione transferase activity
BVD86_RS15325	COG1113	amino acid transport
BVD86_RS15335	COG0523	cobalamin synthesis protein
BVD86_RS15345	COG2188	Transcriptional regulator
BVD86_RS15375	COG0010	Belongs to the arginase family
BVD86_RS15385	COG0546	phosphoglycolate phosphatase activity
BVD86_RS15390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVD86_RS15400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVD86_RS15410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVD86_RS15415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVD86_RS15520	COG0534	Mate efflux family protein
BVD86_RS15525	COG0436	Aminotransferase
BVD86_RS15530	COG2733	membrane
BVD86_RS15545	COG2918	glutathione biosynthetic process
BVD86_RS15595	COG3150	esterase
BVD86_RS15605	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BVD86_RS15615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_RS15625	COG2233	PERMEase
BVD86_RS15630	COG2351	hydroxyisourate hydrolase activity
BVD86_RS15665	COG3706	GGDEF domain
BVD86_RS15680	COG1393	Belongs to the ArsC family
BVD86_RS15685	COG0708	Exodeoxyribonuclease III
BVD86_RS15715	COG0189	ligase activity
BVD86_RS15735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVD86_RS15745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVD86_RS15760	COG4942	peptidase
BVD86_RS15770	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVD86_RS15780	COG2119	membrane
BVD86_RS15790	COG0426	domain, Protein
BVD86_RS15790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS15810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVD86_RS15830	COG1902	pentaerythritol trinitrate reductase activity
BVD86_RS15835	COG1519	Transferase
BVD86_RS15840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVD86_RS15845	COG0668	transmembrane transport
BVD86_RS15855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVD86_RS15860	COG1335	isochorismatase
BVD86_RS15865	COG1522	sequence-specific DNA binding
BVD86_RS15890	COG0784	Response regulator, receiver
BVD86_RS15890	COG2198	Histidine kinase
BVD86_RS15890	COG2205	protein histidine kinase activity
BVD86_RS15895	COG3162	membrane
BVD86_RS15900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVD86_RS15910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVD86_RS15930	COG1309	transcriptional regulator
BVD86_RS15950	COG4221	oxidoreductase activity
BVD86_RS15960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVD86_RS15960	COG0351	phosphomethylpyrimidine kinase
BVD86_RS15960	COG0352	thiamine-phosphate diphosphorylase activity
BVD86_RS15970	COG2814	Major facilitator Superfamily
BVD86_RS15985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BVD86_RS16005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVD86_RS16010	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS16020	COG1335	isochorismatase
BVD86_RS16060	COG2814	Major facilitator Superfamily
BVD86_RS16065	COG0583	DNA-binding transcription factor activity
BVD86_RS16085	COG0667	Aldo Keto reductase
BVD86_RS16105	COG1309	transcriptional regulator
BVD86_RS16130	COG1733	regulation of RNA biosynthetic process
BVD86_RS16140	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_RS16160	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BVD86_RS16165	COG2207	Transcriptional regulator
BVD86_RS16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVD86_RS16240	COG0697	spore germination
BVD86_RS16260	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BVD86_RS16270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BVD86_RS16300	COG0427	acetyl-CoA hydrolase
BVD86_RS16325	COG0659	secondary active sulfate transmembrane transporter activity
BVD86_RS16330	COG4221	oxidoreductase activity
BVD86_RS16335	COG2873	o-acetylhomoserine
BVD86_RS16340	COG0488	(ABC) transporter
BVD86_RS16425	COG0833	amino acid
BVD86_RS16470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVD86_RS16475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVD86_RS16490	COG2226	methyltransferase
BVD86_RS16540	COG0067	glutamate synthase
BVD86_RS16540	COG0069	glutamate synthase activity
BVD86_RS16540	COG0070	glutamate synthase
BVD86_RS16545	COG0493	'glutamate synthase
BVD86_RS16555	COG1704	LemA family
BVD86_RS16560	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BVD86_RS16575	COG3307	-O-antigen
BVD86_RS16600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVD86_RS16615	COG0194	GDP metabolic process
BVD86_RS16665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVD86_RS16675	COG0335	large ribosomal subunit rRNA binding
BVD86_RS16685	COG5380	lipid catabolic process
BVD86_RS16690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVD86_RS16705	COG5006	permease, DMT superfamily
BVD86_RS16710	COG5006	permease, DMT superfamily
BVD86_RS16715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVD86_RS16720	COG0277	FAD linked oxidase domain protein
BVD86_RS16730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVD86_RS16735	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_RS16750	COG1289	transmembrane transporter activity
BVD86_RS16760	COG0628	permease
BVD86_RS16765	COG1192	Involved in chromosome partitioning
BVD86_RS16795	COG0833	amino acid
BVD86_RS16800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD86_RS16805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVD86_RS16815	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_RS16855	COG0583	DNA-binding transcription factor activity
BVD86_RS16885	COG0752	glycyl-tRNA synthetase alpha subunit
BVD86_RS16915	COG0517	IMP dehydrogenase activity
BVD86_RS16915	COG0617	tRNA 3'-terminal CCA addition
BVD86_RS16915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BVD86_RS16920	COG1983	PspC domain protein
BVD86_RS16930	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS16945	COG0408	coproporphyrinogen oxidase activity
BVD86_RS16965	COG0513	Belongs to the DEAD box helicase family
BVD86_RS16975	COG1127	ABC transporter
BVD86_RS16980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVD86_RS16990	COG2854	intermembrane phospholipid transfer
BVD86_RS17000	COG0598	Magnesium transport protein CorA
BVD86_RS17010	COG0494	nUDIX hydrolase
BVD86_RS17015	COG1040	competence protein
BVD86_RS17020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVD86_RS17035	COG2937	Belongs to the GPAT DAPAT family
BVD86_RS17040	COG1946	Acyl-CoA thioesterase
BVD86_RS17045	COG1301	dicarboxylic acid transport
BVD86_RS17060	COG1959	2 iron, 2 sulfur cluster binding
BVD86_RS17065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_RS17065	COG1017	nitric oxide dioxygenase activity
BVD86_RS17075	COG0433	COG0433 Predicted ATPase
BVD86_RS17080	COG0626	cystathionine gamma-synthase activity
BVD86_RS17095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVD86_RS17100	COG0088	Forms part of the polypeptide exit tunnel
BVD86_RS17235	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS17240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BVD86_RS17270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BVD86_RS17275	COG0339	signal peptide processing
BVD86_RS17280	COG0557	exoribonuclease II activity
BVD86_RS17330	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVD86_RS17335	COG1295	ribonuclease BN
BVD86_RS17370	COG1702	phosphate starvation-inducible protein PhoH
BVD86_RS17380	COG0741	lytic transglycosylase activity
BVD86_RS17380	COG0739	heme binding
BVD86_RS17380	COG1196	nuclear chromosome segregation
BVD86_RS17410	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVD86_RS17415	COG1183	phosphatidylcholine synthase activity
BVD86_RS17460	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS17465	COG1309	transcriptional regulator
BVD86_RS17480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVD86_RS17485	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS17505	COG2969	positive regulation of protein catabolic process
BVD86_RS17515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVD86_RS17520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVD86_RS17525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVD86_RS17530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVD86_RS17535	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVD86_RS17555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVD86_RS17565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVD86_RS17570	COG1408	metallophosphoesterase
BVD86_RS17575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVD86_RS17575	COG2885	chlorophyll binding
BVD86_RS17580	COG2199	diguanylate cyclase activity
BVD86_RS17625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_RS17650	COG1607	acyl-coa hydrolase
BVD86_RS17685	COG2350	Protein conserved in bacteria
BVD86_RS17700	COG3781	membrane
BVD86_RS17710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVD86_RS17715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVD86_RS17725	COG1862	Preprotein translocase
BVD86_RS17805	COG3646	Phage regulatory protein
BVD86_RS17975	COG4695	Portal protein
BVD86_RS17985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_RS17985	COG2198	Histidine kinase
BVD86_RS17985	COG2205	protein histidine kinase activity
BVD86_RS17985	COG0784	Response regulator, receiver
BVD86_RS17990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BVD86_RS18010	COG0726	polysaccharide deacetylase
BVD86_RS18015	COG0463	Glycosyl transferase, family 2
BVD86_RS18020	COG0438	transferase activity, transferring glycosyl groups
BVD86_RS18085	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS18090	COG1960	acyl-CoA dehydrogenase activity
BVD86_RS18100	COG2205	protein histidine kinase activity
BVD86_RS18105	COG0745	RESPONSE REGULATOR receiver
BVD86_RS18115	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BVD86_RS18135	COG2096	Adenosyltransferase
BVD86_RS18140	COG4206	TonB-dependent receptor
BVD86_RS18185	COG0285	dihydrofolate synthase activity
BVD86_RS18205	COG0450	alkyl hydroperoxide reductase
BVD86_RS18220	COG0477	Major facilitator Superfamily
BVD86_RS18225	COG1272	protein, Hemolysin III
BVD86_RS18235	COG2153	protein acetylation
BVD86_RS18255	COG0183	Belongs to the thiolase family
BVD86_RS18260	COG2207	Transcriptional regulator
BVD86_RS18280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_RS18300	COG0183	Belongs to the thiolase family
BVD86_RS18310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVD86_RS18310	COG2885	chlorophyll binding
BVD86_RS18315	COG1690	Belongs to the RtcB family
BVD86_RS18320	COG0833	amino acid
BVD86_RS18330	COG2233	PERMEase
BVD86_RS18335	COG1217	gtp-binding protein TYPA
BVD86_RS18350	COG4580	involved in the transport of maltose and maltodextrins
BVD86_RS18365	COG2094	Belongs to the DNA glycosylase MPG family
BVD86_RS18370	COG4772	TonB-dependent receptor
BVD86_RS18375	COG1902	pentaerythritol trinitrate reductase activity
BVD86_RS18390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVD86_RS18395	COG0354	folic acid binding
BVD86_RS18415	COG2233	PERMEase
BVD86_RS18420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_RS18425	COG0251	oxidation-reduction process
BVD86_RS18430	COG1335	isochorismatase
BVD86_RS18435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_RS18440	COG0778	Nitroreductase
BVD86_RS18445	COG0596	Alpha beta hydrolase
BVD86_RS18450	COG3189	MarR family transcriptional regulator
BVD86_RS18455	COG2824	Alkylphosphonate utilization operon protein PhnA
BVD86_RS18460	COG3422	double-strand break repair
BVD86_RS18500	COG0840	transmembrane signaling receptor activity
BVD86_RS18520	COG5510	response to toxic substance
BVD86_RS18530	COG2832	Protein of unknown function (DUF454)
BVD86_RS18535	COG1376	ErfK ybiS ycfS ynhG family protein
BVD86_RS18575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVD86_RS18585	COG1289	transmembrane transporter activity
BVD86_RS18590	COG2814	Major facilitator Superfamily
BVD86_RS18615	COG1115	amino acid carrier protein
BVD86_RS18620	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVD86_RS18625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVD86_RS18630	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BVD86_RS18655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVD86_RS18665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVD86_RS18670	COG1077	Cell shape determining protein MreB Mrl
BVD86_RS18675	COG1792	Involved in formation and maintenance of cell shape
BVD86_RS18680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BVD86_RS18685	COG0424	maF-like protein
BVD86_RS18690	COG1530	ribonuclease E activity
BVD86_RS18700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_RS18720	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_RS18745	COG2207	Transcriptional regulator
BVD86_RS18785	COG1113	amino acid transport
BVD86_RS18790	COG2828	Protein conserved in bacteria
BVD86_RS18795	COG0142	geranyltranstransferase activity
BVD86_RS18800	COG2315	Protein conserved in bacteria
BVD86_RS18815	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVD86_RS18840	COG2194	sulfuric ester hydrolase activity
BVD86_RS18845	COG0745	RESPONSE REGULATOR receiver
BVD86_RS18850	COG0642	Histidine kinase
BVD86_RS18865	COG0004	ammonium transporteR
BVD86_RS18870	COG0583	DNA-binding transcription factor activity
BVD86_RS18895	COG0525	valine-tRNA ligase activity
BVD86_RS18905	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_RS18915	COG0393	Putative heavy-metal-binding
BVD86_RS18920	COG0393	Putative heavy-metal-binding
BVD86_RS18925	COG1538	Outer membrane efflux protein
BVD86_RS18935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS18940	COG0671	phosphoesterase, PA-phosphatase related
BVD86_RS18965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVD86_RS18980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVD86_RS18980	COG1648	precorrin-2 dehydrogenase activity
BVD86_RS18985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVD86_RS19020	COG0531	amino acid
BVD86_RS19035	COG0321	lipoyl(octanoyl) transferase activity
BVD86_RS19040	COG2921	Belongs to the UPF0250 family
BVD86_RS19085	COG2009	succinate dehydrogenase
BVD86_RS19090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BVD86_RS19095	COG1053	succinate dehydrogenase
BVD86_RS19100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVD86_RS19125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_RS19145	COG2354	Protein conserved in bacteria
BVD86_RS19150	COG2321	neutral zinc metallopeptidase
BVD86_RS19170	COG2843	Capsule synthesis protein
BVD86_RS19190	COG0589	response to stress
BVD86_RS19200	COG0251	oxidation-reduction process
BVD86_RS19205	COG1309	transcriptional regulator
BVD86_RS19220	COG0505	Belongs to the CarA family
BVD86_RS19255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVD86_RS19260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVD86_RS19320	COG0477	Major facilitator Superfamily
BVD86_RS19325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVD86_RS19340	COG1597	lipid kinase activity
BVD86_RS19345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVD86_RS19370	COG0584	glycerophosphoryl diester phosphodiesterase
BVD86_RS19390	COG0741	lytic transglycosylase activity
BVD86_RS19415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVD86_RS19435	COG0583	DNA-binding transcription factor activity
BVD86_RS19480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS19485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVD86_RS19490	COG0778	Nitroreductase
BVD86_RS19505	COG1929	Belongs to the glycerate kinase type-1 family
BVD86_RS19510	COG0243	molybdopterin cofactor binding
BVD86_RS19515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVD86_RS19520	COG3339	Conserved Protein
BVD86_RS19545	COG1115	amino acid carrier protein
BVD86_RS19550	COG1113	amino acid transport
BVD86_RS19560	COG0019	diaminopimelate decarboxylase activity
BVD86_RS19575	COG2267	carboxylic ester hydrolase activity
BVD86_RS19580	COG1280	lysine exporter protein (LysE YggA)
BVD86_RS19585	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BVD86_RS19615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_RS19640	COG0697	spore germination
BVD86_RS19645	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVD86_RS19650	COG1136	(ABC) transporter
BVD86_RS19655	COG2333	competence protein COMEC
BVD86_RS19655	COG0658	competence protein
BVD86_RS19665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVD86_RS19665	COG0616	signal peptide processing
BVD86_RS19670	COG0596	Alpha beta hydrolase
BVD86_RS19675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVD86_RS19685	COG0628	permease
BVD86_RS19740	COG4683	PFAM Phage derived protein Gp49-like (DUF891)