locus-tag	class	description
C6I29_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C6I29_RS00010	COG0592	DNA-directed DNA polymerase activity
C6I29_RS00020	COG0187	DNA topoisomerase II activity
C6I29_RS00025	COG1063	alcohol dehydrogenase
C6I29_RS00035	COG0488	(ABC) transporter
C6I29_RS00060	COG0596	Alpha beta hydrolase
C6I29_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C6I29_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C6I29_RS00085	COG1047	Peptidyl-prolyl cis-trans
C6I29_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C6I29_RS00095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C6I29_RS00100	COG0196	riboflavin kinase activity
C6I29_RS00120	COG1116	anion transmembrane transporter activity
C6I29_RS00125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6I29_RS00130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6I29_RS00135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6I29_RS00140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6I29_RS00145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6I29_RS00145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6I29_RS00160	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS00165	COG0546	phosphoglycolate phosphatase activity
C6I29_RS00180	COG1309	transcriptional regulator
C6I29_RS00190	COG0543	2 iron, 2 sulfur cluster binding
C6I29_RS00200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C6I29_RS00215	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6I29_RS00245	COG1596	polysaccharide export
C6I29_RS00250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6I29_RS00295	COG0438	transferase activity, transferring glycosyl groups
C6I29_RS00300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6I29_RS00310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6I29_RS00320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6I29_RS00335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6I29_RS00340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6I29_RS00355	COG0271	Belongs to the BolA IbaG family
C6I29_RS00370	COG0586	Pfam SNARE associated Golgi protein
C6I29_RS00375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6I29_RS00375	COG0519	Catalyzes the synthesis of GMP from XMP
C6I29_RS00405	COG0281	malic enzyme
C6I29_RS00415	COG0791	NLP P60 protein
C6I29_RS00415	COG1388	LysM domain
C6I29_RS00470	COG2837	iron assimilation
C6I29_RS00475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6I29_RS00480	COG1121	(ABC) transporter
C6I29_RS00540	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS00555	COG0386	Belongs to the glutathione peroxidase family
C6I29_RS00570	COG0697	spore germination
C6I29_RS00580	COG0758	DNA mediated transformation
C6I29_RS00585	COG1652	LysM domain
C6I29_RS00630	COG2814	Major facilitator Superfamily
C6I29_RS00640	COG2814	Major facilitator Superfamily
C6I29_RS00660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6I29_RS00685	COG1253	flavin adenine dinucleotide binding
C6I29_RS00690	COG3012	SEC-C Motif Domain Protein
C6I29_RS00695	COG2860	membrane
C6I29_RS00700	COG0477	Major facilitator Superfamily
C6I29_RS00710	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS00725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6I29_RS00740	COG0606	chelatase, subunit chli
C6I29_RS00750	COG0347	Belongs to the P(II) protein family
C6I29_RS00755	COG0004	ammonium transporteR
C6I29_RS00765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6I29_RS00765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6I29_RS00795	COG0795	lipopolysaccharide-transporting ATPase activity
C6I29_RS00800	COG0795	lipopolysaccharide-transporting ATPase activity
C6I29_RS00805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C6I29_RS00810	COG0793	Belongs to the peptidase S41A family
C6I29_RS00825	COG2197	response regulator
C6I29_RS00835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6I29_RS00850	COG4974	Belongs to the 'phage' integrase family
C6I29_RS00875	COG0772	Belongs to the SEDS family
C6I29_RS00885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6I29_RS00890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6I29_RS00900	COG0494	nUDIX hydrolase
C6I29_RS00935	COG3275	phosphorelay sensor kinase activity
C6I29_RS00945	COG0181	hydroxymethylbilane synthase activity
C6I29_RS00990	COG1716	ATPase activity
C6I29_RS00995	COG0546	phosphoglycolate phosphatase activity
C6I29_RS01065	COG0085	RNA polymerase activity
C6I29_RS01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C6I29_RS01085	COG2056	Na+-H+ antiporter family
C6I29_RS01095	COG0326	Molecular chaperone. Has ATPase activity
C6I29_RS01115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C6I29_RS01145	COG0322	excinuclease ABC activity
C6I29_RS01155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6I29_RS01160	COG1132	(ABC) transporter
C6I29_RS01190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C6I29_RS01200	COG0497	DNA recombination
C6I29_RS01210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6I29_RS01215	COG0697	spore germination
C6I29_RS01220	COG0237	dephospho-CoA kinase activity
C6I29_RS01265	COG0779	Required for maturation of 30S ribosomal subunits
C6I29_RS01270	COG0195	Participates in both transcription termination and antitermination
C6I29_RS01285	COG1320	monovalent cation:proton antiporter activity
C6I29_RS01290	COG2212	antiporter activity
C6I29_RS01295	COG1863	multisubunit Na H antiporter MnhE subunit
C6I29_RS01300	COG0651	ATP synthesis coupled electron transport
C6I29_RS01305	COG1006	Multisubunit Na H antiporter MnhC subunit
C6I29_RS01310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6I29_RS01310	COG2111	Na H antiporter
C6I29_RS01325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C6I29_RS01330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6I29_RS01360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6I29_RS01365	COG1074	ATP-dependent DNA helicase activity
C6I29_RS01370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6I29_RS01380	COG1185	polyribonucleotide nucleotidyltransferase activity
C6I29_RS01385	COG0598	Magnesium transport protein CorA
C6I29_RS01395	COG0484	heat shock protein binding
C6I29_RS01405	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C6I29_RS01415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6I29_RS01435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C6I29_RS01440	COG4535	Mg2 and Co2 transporter CorC
C6I29_RS01450	COG0425	Belongs to the sulfur carrier protein TusA family
C6I29_RS01460	COG0644	oxidoreductase
C6I29_RS01460	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6I29_RS01470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6I29_RS01485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6I29_RS01495	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C6I29_RS01505	COG0493	'glutamate synthase
C6I29_RS01505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6I29_RS01520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6I29_RS01530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6I29_RS01535	COG0534	Mate efflux family protein
C6I29_RS01545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6I29_RS01550	COG1280	lysine exporter protein (LysE YggA)
C6I29_RS01575	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS01580	COG1530	ribonuclease E activity
C6I29_RS01595	COG0546	phosphoglycolate phosphatase activity
C6I29_RS01600	COG3971	2-oxopent-4-enoate hydratase activity
C6I29_RS01605	COG4569	acetaldehyde dehydrogenase (acetylating) activity
C6I29_RS01635	COG0583	DNA-binding transcription factor activity
C6I29_RS01640	COG4638	Rieske (2fe-2S)
C6I29_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS01660	COG3384	dioxygenase
C6I29_RS01665	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6I29_RS01690	COG0753	catalase activity
C6I29_RS01700	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS01715	COG0494	nUDIX hydrolase
C6I29_RS01730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C6I29_RS01745	COG0473	3-isopropylmalate dehydrogenase activity
C6I29_RS01800	COG1560	Kdo2-lipid A biosynthetic process
C6I29_RS01810	COG0488	(ABC) transporter
C6I29_RS01815	COG2900	Belongs to the SlyX family
C6I29_RS01845	COG1929	Belongs to the glycerate kinase type-1 family
C6I29_RS01850	COG0210	DNA helicase
C6I29_RS01855	COG0724	RNA recognition motif
C6I29_RS01870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6I29_RS01870	COG4651	solute:proton antiporter activity
C6I29_RS01895	COG0788	formyltetrahydrofolate deformylase activity
C6I29_RS01930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6I29_RS01950	COG0500	methyltransferase
C6I29_RS02015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6I29_RS02015	COG2813	Specifically methylates the guanine in position
C6I29_RS02020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6I29_RS02025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C6I29_RS02035	COG4774	siderophore transport
C6I29_RS02045	COG0740	serine-type endopeptidase activity
C6I29_RS02060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6I29_RS02060	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6I29_RS02065	COG4106	trans-aconitate 2-methyltransferase activity
C6I29_RS02070	COG0280	phosphate acetyltransferase
C6I29_RS02070	COG0857	belongs to the CobB CobQ family
C6I29_RS02075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6I29_RS02090	COG2267	carboxylic ester hydrolase activity
C6I29_RS02105	COG0793	Belongs to the peptidase S41A family
C6I29_RS02140	COG1426	Protein conserved in bacteria
C6I29_RS02150	COG0124	histidyl-tRNA synthetase
C6I29_RS02160	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6I29_RS02185	COG1862	Preprotein translocase
C6I29_RS02195	COG1704	LemA family
C6I29_RS02220	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C6I29_RS02235	COG0726	polysaccharide deacetylase
C6I29_RS02240	COG0438	transferase activity, transferring glycosyl groups
C6I29_RS02265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C6I29_RS02310	COG0577	efflux transmembrane transporter activity
C6I29_RS02310	COG1136	(ABC) transporter
C6I29_RS02315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6I29_RS02340	COG0028	Belongs to the TPP enzyme family
C6I29_RS02360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C6I29_RS02375	COG0084	hydrolase, TatD family'
C6I29_RS02385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6I29_RS02390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6I29_RS02425	COG2890	protein-(glutamine-N5) methyltransferase activity
C6I29_RS02450	COG2814	Major facilitator Superfamily
C6I29_RS02455	COG0697	spore germination
C6I29_RS02480	COG3622	Belongs to the hyi family
C6I29_RS02485	COG2084	Dehydrogenase
C6I29_RS02490	COG1024	Enoyl-CoA hydratase
C6I29_RS02495	COG0784	Response regulator, receiver
C6I29_RS02495	COG2205	protein histidine kinase activity
C6I29_RS02495	COG5002	protein histidine kinase activity
C6I29_RS02515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6I29_RS02525	COG3956	TIGRFAM MazG family protein
C6I29_RS02530	COG1555	photosystem II stabilization
C6I29_RS02535	COG0617	tRNA 3'-terminal CCA addition
C6I29_RS02540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6I29_RS02550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C6I29_RS02555	COG1660	Displays ATPase and GTPase activities
C6I29_RS02560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6I29_RS02565	COG3028	Belongs to the UPF0307 family
C6I29_RS02580	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS02600	COG0625	glutathione transferase activity
C6I29_RS02605	COG1238	metal cluster binding
C6I29_RS02680	COG0037	tRNA processing
C6I29_RS02720	COG1764	response to oxidative stress
C6I29_RS02725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6I29_RS02775	COG2969	positive regulation of protein catabolic process
C6I29_RS02780	COG0625	glutathione transferase activity
C6I29_RS02785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C6I29_RS02800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C6I29_RS02805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C6I29_RS02810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6I29_RS02820	COG1346	cytolysis
C6I29_RS02830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6I29_RS02840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6I29_RS02845	COG1408	metallophosphoesterase
C6I29_RS02850	COG0477	Major facilitator Superfamily
C6I29_RS02855	COG1272	protein, Hemolysin III
C6I29_RS02865	COG4667	esterase of the alpha-beta hydrolase superfamily
C6I29_RS02875	COG1024	Enoyl-CoA hydratase
C6I29_RS02875	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6I29_RS02880	COG0183	Belongs to the thiolase family
C6I29_RS02885	COG2207	Transcriptional regulator
C6I29_RS02895	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6I29_RS02905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C6I29_RS02915	COG1289	transmembrane transporter activity
C6I29_RS02920	COG2814	Major facilitator Superfamily
C6I29_RS02935	COG0786	glutamate:sodium symporter activity
C6I29_RS02940	COG1115	amino acid carrier protein
C6I29_RS02945	COG2059	Chromate
C6I29_RS02950	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6I29_RS02970	COG4770	biotin carboxylase activity
C6I29_RS02975	COG1024	Enoyl-CoA hydratase
C6I29_RS02980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6I29_RS02985	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS02990	COG1309	transcriptional regulator
C6I29_RS02995	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS03000	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6I29_RS03025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6I29_RS03035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6I29_RS03040	COG1077	Cell shape determining protein MreB Mrl
C6I29_RS03045	COG1792	Involved in formation and maintenance of cell shape
C6I29_RS03050	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6I29_RS03055	COG0424	maF-like protein
C6I29_RS03065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6I29_RS03075	COG0560	Phosphoserine phosphatase
C6I29_RS03095	COG0642	Histidine kinase
C6I29_RS03105	COG2194	sulfuric ester hydrolase activity
C6I29_RS03115	COG1113	amino acid transport
C6I29_RS03120	COG2828	Protein conserved in bacteria
C6I29_RS03125	COG2824	Alkylphosphonate utilization operon protein PhnA
C6I29_RS03130	COG0142	geranyltranstransferase activity
C6I29_RS03145	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6I29_RS03155	COG2814	Major facilitator Superfamily
C6I29_RS03170	COG1309	transcriptional regulator
C6I29_RS03190	COG0004	ammonium transporteR
C6I29_RS03195	COG1126	abc transporter atp-binding protein
C6I29_RS03200	COG0765	amino acid transport
C6I29_RS03205	COG0765	amino acid transport
C6I29_RS03235	COG0525	valine-tRNA ligase activity
C6I29_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS03255	COG0393	Putative heavy-metal-binding
C6I29_RS03260	COG1538	Outer membrane efflux protein
C6I29_RS03270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6I29_RS03275	COG0671	phosphoesterase, PA-phosphatase related
C6I29_RS03290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C6I29_RS03295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C6I29_RS03300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C6I29_RS03325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6I29_RS03340	COG1648	precorrin-2 dehydrogenase activity
C6I29_RS03340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C6I29_RS03345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6I29_RS03350	COG0531	amino acid
C6I29_RS03365	COG0321	lipoyl(octanoyl) transferase activity
C6I29_RS03390	COG0586	Pfam SNARE associated Golgi protein
C6I29_RS03410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6I29_RS03430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6I29_RS03460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C6I29_RS03475	COG0358	DNA primase activity
C6I29_RS03485	COG0564	pseudouridine synthase activity
C6I29_RS03505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6I29_RS03535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C6I29_RS03535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6I29_RS03555	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6I29_RS03560	COG1053	succinate dehydrogenase
C6I29_RS03580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6I29_RS03590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6I29_RS03600	COG2354	Protein conserved in bacteria
C6I29_RS03605	COG2321	neutral zinc metallopeptidase
C6I29_RS03640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6I29_RS03645	COG0505	Belongs to the CarA family
C6I29_RS03670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6I29_RS03675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6I29_RS03710	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
C6I29_RS03715	COG1597	lipid kinase activity
C6I29_RS03730	COG0459	protein refolding
C6I29_RS03760	COG1484	DNA-dependent DNA replication
C6I29_RS03775	COG3655	Transcriptional regulator
C6I29_RS03790	COG0582	viral genome integration into host DNA
C6I29_RS03805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6I29_RS03810	COG2239	Acts as a magnesium transporter
C6I29_RS03820	COG0501	Belongs to the peptidase M48B family
C6I29_RS03825	COG1196	nuclear chromosome segregation
C6I29_RS03825	COG0741	lytic transglycosylase activity
C6I29_RS03825	COG0739	heme binding
C6I29_RS03830	COG0037	tRNA processing
C6I29_RS03840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C6I29_RS03845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6I29_RS03975	COG0183	Belongs to the thiolase family
C6I29_RS03980	COG0427	acetyl-CoA hydrolase
C6I29_RS03985	COG4829	muconolactone delta-isomerase
C6I29_RS03995	COG2814	Major facilitator Superfamily
C6I29_RS04000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6I29_RS04010	COG0583	DNA-binding transcription factor activity
C6I29_RS04015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6I29_RS04020	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
C6I29_RS04030	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS04035	COG0583	DNA-binding transcription factor activity
C6I29_RS04040	COG3177	Filamentation induced by cAMP protein fic
C6I29_RS04045	COG0697	spore germination
C6I29_RS04050	COG1113	amino acid transport
C6I29_RS04055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6I29_RS04065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6I29_RS04085	COG4221	oxidoreductase activity
C6I29_RS04090	COG0583	DNA-binding transcription factor activity
C6I29_RS04095	COG1064	alcohol dehydrogenase
C6I29_RS04100	COG0604	alcohol dehydrogenase
C6I29_RS04100	COG3321	synthase
C6I29_RS04115	COG1695	Transcriptional regulator
C6I29_RS04120	COG1309	transcriptional regulator
C6I29_RS04125	COG0604	alcohol dehydrogenase
C6I29_RS04145	COG1063	alcohol dehydrogenase
C6I29_RS04170	COG2801	Transposase and inactivated derivatives
C6I29_RS04210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C6I29_RS04220	COG1979	alcohol dehydrogenase
C6I29_RS04230	COG1902	pentaerythritol trinitrate reductase activity
C6I29_RS04240	COG1309	transcriptional regulator
C6I29_RS04245	COG2130	NADP-dependent
C6I29_RS04305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6I29_RS04320	COG2871	sodium ion transport
C6I29_RS04360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C6I29_RS04420	COG1215	transferase activity, transferring glycosyl groups
C6I29_RS04445	COG0439	Biotin carboxylase
C6I29_RS04460	COG0864	Transcriptional regulator
C6I29_RS04470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6I29_RS04495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6I29_RS04500	COG2814	Major facilitator Superfamily
C6I29_RS04515	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6I29_RS04525	COG0154	amidase activity
C6I29_RS04555	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS04565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6I29_RS04680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C6I29_RS04685	COG3739	integral membrane protein
C6I29_RS04705	COG0302	gtp cyclohydrolase
C6I29_RS04720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6I29_RS04725	COG0512	Glutamine amidotransferase of anthranilate synthase
C6I29_RS04730	COG0174	glutamine synthetase
C6I29_RS04745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C6I29_RS04780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6I29_RS04785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6I29_RS04790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6I29_RS04805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6I29_RS04815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C6I29_RS04820	COG0415	Belongs to the DNA photolyase family
C6I29_RS04830	COG1252	NADH dehydrogenase
C6I29_RS04835	COG1686	Belongs to the peptidase S11 family
C6I29_RS04875	COG1823	symporter activity
C6I29_RS04880	COG0612	Peptidase, M16
C6I29_RS04900	COG3025	triphosphatase activity
C6I29_RS04910	COG0352	thiamine-phosphate diphosphorylase activity
C6I29_RS04965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6I29_RS04970	COG0076	glutamate decarboxylase activity
C6I29_RS04975	COG1522	sequence-specific DNA binding
C6I29_RS04980	COG3961	Belongs to the TPP enzyme family
C6I29_RS04985	COG1113	amino acid transport
C6I29_RS04995	COG0573	inorganic phosphate transmembrane transporter activity
C6I29_RS05005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6I29_RS05015	COG0616	signal peptide processing
C6I29_RS05035	COG2915	High frequency lysogenization protein hflD homolog
C6I29_RS05055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6I29_RS05060	COG1686	Belongs to the peptidase S11 family
C6I29_RS05085	COG0583	DNA-binding transcription factor activity
C6I29_RS05090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6I29_RS05095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6I29_RS05100	COG1067	ATP-dependent peptidase activity
C6I29_RS05145	COG1966	Carbon starvation protein
C6I29_RS05150	COG2879	small protein
C6I29_RS05155	COG0714	Associated with various cellular activities
C6I29_RS05190	COG0659	secondary active sulfate transmembrane transporter activity
C6I29_RS05200	COG2252	PERMEase
C6I29_RS05205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C6I29_RS05215	COG1215	transferase activity, transferring glycosyl groups
C6I29_RS05225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C6I29_RS05235	COG0527	aspartate kinase activity
C6I29_RS05245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6I29_RS05260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C6I29_RS05275	COG0667	Aldo Keto reductase
C6I29_RS05285	COG1765	OsmC-like protein
C6I29_RS05305	COG0540	Belongs to the ATCase OTCase family
C6I29_RS05315	COG2885	chlorophyll binding
C6I29_RS05315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6I29_RS05330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6I29_RS05330	COG0596	Alpha beta hydrolase
C6I29_RS05330	COG2226	methyltransferase
C6I29_RS05335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C6I29_RS05370	COG1278	Cold shock
C6I29_RS05375	COG0513	Belongs to the DEAD box helicase family
C6I29_RS05385	COG0778	Nitroreductase
C6I29_RS05415	COG1286	toxin biosynthetic process
C6I29_RS05440	COG4783	chaperone-mediated protein folding
C6I29_RS05445	COG1610	YqeY-like protein
C6I29_RS05475	COG0515	serine threonine protein kinase
C6I29_RS05475	COG2815	serine threonine protein kinase
C6I29_RS05555	COG2308	Evidence 4 Homologs of previously reported genes of
C6I29_RS05575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6I29_RS05580	COG0305	Participates in initiation and elongation during chromosome replication
C6I29_RS05590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6I29_RS05595	COG0360	Binds together with S18 to 16S ribosomal RNA
C6I29_RS05605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6I29_RS05610	COG1845	cytochrome c oxidase, subunit III
C6I29_RS05615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6I29_RS05620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6I29_RS05645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C6I29_RS05665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6I29_RS05680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C6I29_RS05685	COG2890	protein-(glutamine-N5) methyltransferase activity
C6I29_RS05700	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS05705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6I29_RS05725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6I29_RS05745	COG0729	surface antigen
C6I29_RS05750	COG2911	Protein conserved in bacteria
C6I29_RS05785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6I29_RS05790	COG4605	iron ion homeostasis
C6I29_RS05795	COG4604	ABC transporter, ATP-binding protein
C6I29_RS05800	COG4607	ABC-type enterochelin transport system periplasmic component
C6I29_RS05805	COG2814	Major facilitator Superfamily
C6I29_RS05810	COG0786	glutamate:sodium symporter activity
C6I29_RS05815	COG0583	DNA-binding transcription factor activity
C6I29_RS05820	COG2707	UPF0756 membrane protein
C6I29_RS05840	COG0564	pseudouridine synthase activity
C6I29_RS05845	COG0802	atpase or kinase
C6I29_RS05850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C6I29_RS05860	COG1923	regulation of RNA biosynthetic process
C6I29_RS05865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6I29_RS05880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C6I29_RS05890	COG1192	Involved in chromosome partitioning
C6I29_RS05895	COG1475	DNA binding
C6I29_RS05900	COG0811	peptide transport
C6I29_RS05910	COG1132	(ABC) transporter
C6I29_RS05915	COG1663	tetraacyldisaccharide 4'-kinase activity
C6I29_RS05935	COG0084	hydrolase, TatD family'
C6I29_RS05945	COG2165	general secretion pathway protein
C6I29_RS05960	COG3156	type II secretion system protein K
C6I29_RS06000	COG0776	regulation of translation
C6I29_RS06020	COG1396	sequence-specific DNA binding
C6I29_RS06030	COG2431	L-lysine efflux transmembrane transporter activity
C6I29_RS06045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6I29_RS06055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6I29_RS06070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C6I29_RS06075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6I29_RS06080	COG0022	dehydrogenase e1 component
C6I29_RS06085	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6I29_RS06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6I29_RS06095	COG1063	alcohol dehydrogenase
C6I29_RS06130	COG1114	Component of the transport system for branched-chain amino acids
C6I29_RS06135	COG0024	Methionine aminopeptidase
C6I29_RS06140	COG0583	DNA-binding transcription factor activity
C6I29_RS06150	COG0583	DNA-binding transcription factor activity
C6I29_RS06155	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS06160	COG2814	Major facilitator Superfamily
C6I29_RS06170	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6I29_RS06180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6I29_RS06195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6I29_RS06200	COG0569	domain protein
C6I29_RS06205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6I29_RS06210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C6I29_RS06220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6I29_RS06230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C6I29_RS06235	COG0542	response to heat
C6I29_RS06265	COG0372	Belongs to the citrate synthase family
C6I29_RS06275	COG2204	response regulator
C6I29_RS06280	COG3852	Histidine kinase
C6I29_RS06295	COG0233	cytoplasmic translational termination
C6I29_RS06300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6I29_RS06305	COG0575	Belongs to the CDS family
C6I29_RS06320	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6I29_RS06340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6I29_RS06355	COG2137	regulation of response to DNA damage stimulus
C6I29_RS06360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C6I29_RS06365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6I29_RS06370	COG1011	Hydrolase
C6I29_RS06385	COG0268	Binds directly to 16S ribosomal RNA
C6I29_RS06390	COG0702	epimerase
C6I29_RS06395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C6I29_RS06410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6I29_RS06440	COG0316	Belongs to the HesB IscA family
C6I29_RS06445	COG0822	iron-sulfur transferase activity
C6I29_RS06470	COG0776	regulation of translation
C6I29_RS06475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6I29_RS06485	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS06490	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS06550	COG1278	Cold shock
C6I29_RS06555	COG2323	membrane
C6I29_RS06560	COG0671	phosphoesterase, PA-phosphatase related
C6I29_RS06570	COG2819	hydrolase of the alpha beta superfamily
C6I29_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS06650	COG0439	Biotin carboxylase
C6I29_RS06660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C6I29_RS06685	COG0582	viral genome integration into host DNA
C6I29_RS06810	COG1783	phage Terminase large subunit
C6I29_RS06845	COG4387	Mu-like prophage protein GP36
C6I29_RS07000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6I29_RS07060	COG1271	oxidase subunit
C6I29_RS07065	COG1294	oxidase, subunit
C6I29_RS07080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6I29_RS07125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6I29_RS07130	COG1027	Aspartate ammonia-lyase
C6I29_RS07140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6I29_RS07150	COG1448	Aminotransferase
C6I29_RS07155	COG1113	amino acid transport
C6I29_RS07170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6I29_RS07175	COG2814	Major facilitator Superfamily
C6I29_RS07180	COG0509	glycine decarboxylation via glycine cleavage system
C6I29_RS07195	COG1132	(ABC) transporter
C6I29_RS07200	COG2199	diguanylate cyclase activity
C6I29_RS07200	COG2203	Gaf domain
C6I29_RS07215	COG3706	GGDEF domain
C6I29_RS07220	COG2801	Transposase and inactivated derivatives
C6I29_RS07235	COG0668	transmembrane transport
C6I29_RS07240	COG3122	Protein conserved in bacteria
C6I29_RS07260	COG0640	Transcriptional regulator
C6I29_RS07265	COG0783	Belongs to the Dps family
C6I29_RS07290	COG0235	Class ii aldolase
C6I29_RS07300	COG1024	Enoyl-CoA hydratase
C6I29_RS07320	COG3781	membrane
C6I29_RS07330	COG2985	domain, Protein
C6I29_RS07365	COG0583	DNA-binding transcription factor activity
C6I29_RS07400	COG1396	sequence-specific DNA binding
C6I29_RS07400	COG3800	Transcriptional regulator
C6I29_RS07425	COG0477	Major facilitator Superfamily
C6I29_RS07430	COG1024	Enoyl-CoA hydratase
C6I29_RS07435	COG1024	Enoyl-CoA hydratase
C6I29_RS07440	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS07445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6I29_RS07460	COG0583	DNA-binding transcription factor activity
C6I29_RS07470	COG3327	negative regulation of DNA-templated transcription, initiation
C6I29_RS07475	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6I29_RS07480	COG1024	Enoyl-CoA hydratase
C6I29_RS07485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6I29_RS07490	COG2151	metal-sulfur cluster biosynthetic enzyme
C6I29_RS07495	COG3396	Phenylacetate-CoA oxygenase
C6I29_RS07500	COG3460	Phenylacetate-CoA oxygenase
C6I29_RS07505	COG3396	Phenylacetate-CoA oxygenase
C6I29_RS07510	COG2030	dehydratase
C6I29_RS07510	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS07520	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C6I29_RS07525	COG4149	molybdate abc transporter
C6I29_RS07530	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6I29_RS07535	COG0303	'Molybdopterin
C6I29_RS07540	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6I29_RS07540	COG0315	cyclic pyranopterin monophosphate synthase activity
C6I29_RS07545	COG0314	molybdopterin synthase activity
C6I29_RS07555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C6I29_RS07565	COG0243	molybdopterin cofactor binding
C6I29_RS07575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6I29_RS07580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6I29_RS07585	COG2223	nitrite transmembrane transporter activity
C6I29_RS07615	COG1570	exodeoxyribonuclease VII activity
C6I29_RS07640	COG2814	Major facilitator Superfamily
C6I29_RS07650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6I29_RS07660	COG2814	Major facilitator Superfamily
C6I29_RS07665	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS07670	COG0183	Belongs to the thiolase family
C6I29_RS07685	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS07690	COG2814	Major facilitator Superfamily
C6I29_RS07695	COG2814	Major facilitator Superfamily
C6I29_RS07705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6I29_RS07710	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS07715	COG2814	Major facilitator Superfamily
C6I29_RS07720	COG0644	oxidoreductase
C6I29_RS07720	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C6I29_RS07745	COG0583	DNA-binding transcription factor activity
C6I29_RS07750	COG1380	Effector of murein hydrolase LrgA
C6I29_RS07765	COG0406	alpha-ribazole phosphatase activity
C6I29_RS07770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C6I29_RS07815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6I29_RS07850	COG2826	transposase and inactivated derivatives, IS30 family
C6I29_RS07860	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C6I29_RS07865	COG2826	transposase and inactivated derivatives, IS30 family
C6I29_RS07880	COG1294	oxidase, subunit
C6I29_RS07885	COG4890	Cyd operon protein YbgT
C6I29_RS07905	COG0552	protein localization to endoplasmic reticulum
C6I29_RS07910	COG0612	Peptidase, M16
C6I29_RS07940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6I29_RS07940	COG0517	IMP dehydrogenase activity
C6I29_RS07945	COG0133	tryptophan synthase activity
C6I29_RS07975	COG2826	transposase and inactivated derivatives, IS30 family
C6I29_RS07980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C6I29_RS08005	COG0798	PFAM Bile acid sodium symporter
C6I29_RS08010	COG0640	Transcriptional regulator
C6I29_RS08060	COG1278	Cold shock
C6I29_RS08065	COG1560	Kdo2-lipid A biosynthetic process
C6I29_RS08080	COG0537	adenosine 5'-monophosphoramidase activity
C6I29_RS08105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6I29_RS08125	COG0730	response to heat
C6I29_RS08160	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C6I29_RS08165	COG0148	phosphopyruvate hydratase activity
C6I29_RS08200	COG1902	pentaerythritol trinitrate reductase activity
C6I29_RS08200	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6I29_RS08210	COG2267	carboxylic ester hydrolase activity
C6I29_RS08215	COG0583	DNA-binding transcription factor activity
C6I29_RS08220	COG4948	Mandelate Racemase Muconate Lactonizing
C6I29_RS08225	COG4829	muconolactone delta-isomerase
C6I29_RS08235	COG4638	Rieske (2fe-2S)
C6I29_RS08240	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6I29_RS08245	COG0543	2 iron, 2 sulfur cluster binding
C6I29_RS08245	COG0633	Ferredoxin
C6I29_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS08255	COG3135	benzoate transporter
C6I29_RS08260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6I29_RS08265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6I29_RS08270	COG0183	Belongs to the thiolase family
C6I29_RS08275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6I29_RS08280	COG2814	Major facilitator Superfamily
C6I29_RS08290	COG0477	Major facilitator Superfamily
C6I29_RS08295	COG0596	Alpha beta hydrolase
C6I29_RS08305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6I29_RS08325	COG2351	hydroxyisourate hydrolase activity
C6I29_RS08330	COG4772	TonB-dependent receptor
C6I29_RS08345	COG2084	Dehydrogenase
C6I29_RS08350	COG2233	PERMEase
C6I29_RS08355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6I29_RS08360	COG0251	oxidation-reduction process
C6I29_RS08365	COG1335	isochorismatase
C6I29_RS08370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6I29_RS08380	COG0596	Alpha beta hydrolase
C6I29_RS08395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6I29_RS08405	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6I29_RS08415	COG0697	spore germination
C6I29_RS08440	COG0424	maF-like protein
C6I29_RS08445	COG2850	peptidyl-arginine hydroxylation
C6I29_RS08450	COG0069	glutamate synthase activity
C6I29_RS08475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6I29_RS08480	COG1454	alcohol dehydrogenase
C6I29_RS08485	COG0824	Thioesterase
C6I29_RS08490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6I29_RS08515	COG0183	Belongs to the thiolase family
C6I29_RS08530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6I29_RS08540	COG3135	benzoate transporter
C6I29_RS08545	COG2076	Multidrug Resistance protein
C6I29_RS08560	COG0589	response to stress
C6I29_RS08565	COG0308	aminopeptidase N
C6I29_RS08585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6I29_RS08590	COG1454	alcohol dehydrogenase
C6I29_RS08610	COG0531	amino acid
C6I29_RS08615	COG4303	Ethanolamine ammonia lyase large subunit
C6I29_RS08620	COG4302	ethanolamine ammonia-lyase activity
C6I29_RS08625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6I29_RS08625	COG0519	Catalyzes the synthesis of GMP from XMP
C6I29_RS08630	COG2353	YceI-like domain
C6I29_RS08640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6I29_RS08675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6I29_RS08675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6I29_RS08745	COG1464	Belongs to the NlpA lipoprotein family
C6I29_RS08750	COG1464	Belongs to the NlpA lipoprotein family
C6I29_RS08755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6I29_RS08760	COG2011	ABC-type metal ion transport system permease component
C6I29_RS08765	COG0012	GTP binding
C6I29_RS08780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6I29_RS08795	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C6I29_RS08800	COG0436	Aminotransferase
C6I29_RS08805	COG0386	Belongs to the glutathione peroxidase family
C6I29_RS08810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6I29_RS08815	COG0436	Aminotransferase
C6I29_RS08820	COG1464	Belongs to the NlpA lipoprotein family
C6I29_RS08825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6I29_RS08830	COG2011	ABC-type metal ion transport system permease component
C6I29_RS08865	COG0242	peptide deformylase activity
C6I29_RS08880	COG0028	Belongs to the TPP enzyme family
C6I29_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS08900	COG2267	carboxylic ester hydrolase activity
C6I29_RS08910	COG2271	Major facilitator Superfamily
C6I29_RS08915	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6I29_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS08945	COG1414	Transcriptional regulator
C6I29_RS08950	COG4638	Rieske (2fe-2S)
C6I29_RS08955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6I29_RS08960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6I29_RS08960	COG0543	2 iron, 2 sulfur cluster binding
C6I29_RS08970	COG2271	Major facilitator Superfamily
C6I29_RS08975	COG2207	Transcriptional regulator
C6I29_RS09000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6I29_RS09020	COG3052	prosthetic group binding
C6I29_RS09025	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C6I29_RS09040	COG0583	DNA-binding transcription factor activity
C6I29_RS09080	COG3706	GGDEF domain
C6I29_RS09085	COG1280	lysine exporter protein (LysE YggA)
C6I29_RS09090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6I29_RS09130	COG0583	DNA-binding transcription factor activity
C6I29_RS09140	COG2814	Major facilitator Superfamily
C6I29_RS09145	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS09155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6I29_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS09205	COG4264	IucA IucC family
C6I29_RS09210	COG4264	IucA IucC family
C6I29_RS09230	COG0789	Transcriptional regulator
C6I29_RS09250	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6I29_RS09260	COG4122	O-methyltransferase activity
C6I29_RS09275	COG1739	Uncharacterized protein family UPF0029
C6I29_RS09290	COG1538	Outer membrane efflux protein
C6I29_RS09295	COG2826	transposase and inactivated derivatives, IS30 family
C6I29_RS09300	COG1137	ATPase activity
C6I29_RS09305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6I29_RS09315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6I29_RS09320	COG0517	IMP dehydrogenase activity
C6I29_RS09320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6I29_RS09335	COG1683	Conserved Protein
C6I29_RS09345	COG1228	amidohydrolase
C6I29_RS09355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C6I29_RS09380	COG0830	nickel cation binding
C6I29_RS09400	COG0804	urea catabolic process
C6I29_RS09425	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS09430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6I29_RS09435	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS09455	COG4232	protein-disulfide reductase activity
C6I29_RS09460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6I29_RS09465	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS09470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6I29_RS09475	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS09495	COG0531	amino acid
C6I29_RS09525	COG1643	Atp-dependent helicase
C6I29_RS09540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C6I29_RS09550	COG3634	alkyl hydroperoxide reductase activity
C6I29_RS09585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6I29_RS09595	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS09600	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS09605	COG1301	dicarboxylic acid transport
C6I29_RS09620	COG3139	Protein of unknown function (DUF1315)
C6I29_RS09625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C6I29_RS09630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6I29_RS09640	COG0494	nUDIX hydrolase
C6I29_RS09650	COG0642	Histidine kinase
C6I29_RS09660	COG3111	PFAM Bacterial OB fold (BOF) protein
C6I29_RS09665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6I29_RS09670	COG2199	diguanylate cyclase activity
C6I29_RS09670	COG2203	Gaf domain
C6I29_RS09675	COG1720	tRNA m6t6A37 methyltransferase activity
C6I29_RS09685	COG0826	peptidase U32
C6I29_RS09690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6I29_RS09695	COG3634	alkyl hydroperoxide reductase activity
C6I29_RS09715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6I29_RS09755	COG1131	(ABC) transporter
C6I29_RS09760	COG0842	Transport permease protein
C6I29_RS09775	COG0772	Belongs to the SEDS family
C6I29_RS09780	COG2951	lytic endotransglycosylase activity
C6I29_RS09800	COG0052	Belongs to the universal ribosomal protein uS2 family
C6I29_RS09805	COG0024	Methionine aminopeptidase
C6I29_RS09820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6I29_RS09825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C6I29_RS09840	COG2391	methyltransferase activity
C6I29_RS09875	COG3706	GGDEF domain
C6I29_RS09880	COG1253	flavin adenine dinucleotide binding
C6I29_RS09905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C6I29_RS09935	COG3040	lipid binding
C6I29_RS09940	COG0556	nucleotide-excision repair
C6I29_RS09950	COG2199	diguanylate cyclase activity
C6I29_RS09955	COG0436	Aminotransferase
C6I29_RS09985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6I29_RS10000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C6I29_RS10005	COG0571	ribonuclease III activity
C6I29_RS10015	COG0681	Belongs to the peptidase S26 family
C6I29_RS10030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6I29_RS10045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6I29_RS10050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6I29_RS10055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6I29_RS10065	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6I29_RS10070	COG4208	sulfate ABC transporter
C6I29_RS10075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6I29_RS10080	COG0583	DNA-binding transcription factor activity
C6I29_RS10095	COG0602	queuosine metabolic process
C6I29_RS10100	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C6I29_RS10110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6I29_RS10115	COG1051	belongs to the nudix hydrolase family
C6I29_RS10115	COG1056	cytidyltransferase-related domain
C6I29_RS10120	COG1024	Enoyl-CoA hydratase
C6I29_RS10130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6I29_RS10135	COG0300	oxidoreductase activity
C6I29_RS10140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6I29_RS10140	COG0047	phosphoribosylformylglycinamidine synthase activity
C6I29_RS10155	COG2255	four-way junction helicase activity
C6I29_RS10175	COG0824	Thioesterase
C6I29_RS10195	COG0823	Involved in the tonB-independent uptake of proteins
C6I29_RS10215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6I29_RS10255	COG0628	permease
C6I29_RS10260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C6I29_RS10265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6I29_RS10285	COG2333	competence protein COMEC
C6I29_RS10285	COG0658	competence protein
C6I29_RS10290	COG1136	(ABC) transporter
C6I29_RS10310	COG1671	Belongs to the UPF0178 family
C6I29_RS10330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6I29_RS10360	COG1280	lysine exporter protein (LysE YggA)
C6I29_RS10380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C6I29_RS10385	COG0019	diaminopimelate decarboxylase activity
C6I29_RS10395	COG1113	amino acid transport
C6I29_RS10420	COG0174	glutamine synthetase
C6I29_RS10425	COG0745	RESPONSE REGULATOR receiver
C6I29_RS10440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C6I29_RS10445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C6I29_RS10455	COG0833	amino acid
C6I29_RS10465	COG3724	N-succinylarginine dihydrolase activity
C6I29_RS10470	COG1012	belongs to the aldehyde dehydrogenase family
C6I29_RS10475	COG3138	arginine N-succinyltransferase
C6I29_RS10480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6I29_RS10485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6I29_RS10500	COG1902	pentaerythritol trinitrate reductase activity
C6I29_RS10500	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6I29_RS10505	COG0277	FAD linked oxidase domain protein
C6I29_RS10515	COG2186	Transcriptional regulator
C6I29_RS10530	COG3706	GGDEF domain
C6I29_RS10530	COG5001	Diguanylate cyclase
C6I29_RS10530	COG4251	negative regulation of phosphorylation
C6I29_RS10530	COG2203	Gaf domain
C6I29_RS10535	COG0418	dihydroorotase activity
C6I29_RS10540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6I29_RS10555	COG0833	amino acid
C6I29_RS10575	COG4172	Belongs to the ABC transporter superfamily
C6I29_RS10580	COG4239	(ABC) transporter, permease
C6I29_RS10585	COG4174	ABC transporter (Permease)
C6I29_RS10590	COG4166	transmembrane transport
C6I29_RS10595	COG0741	lytic transglycosylase activity
C6I29_RS10595	COG1388	LysM domain
C6I29_RS10595	COG1388	LysM domain
C6I29_RS10595	COG0741	lytic transglycosylase activity
C6I29_RS10600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6I29_RS10610	COG2816	NAD+ diphosphatase activity
C6I29_RS10630	COG3107	peptidoglycan biosynthetic process
C6I29_RS10645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6I29_RS10650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6I29_RS10655	COG0006	proline dipeptidase activity
C6I29_RS10680	COG1522	sequence-specific DNA binding
C6I29_RS10700	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6I29_RS10705	COG2169	Transcriptional regulator
C6I29_RS10705	COG1917	Cupin 2, conserved barrel domain protein
C6I29_RS10720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6I29_RS10730	COG2234	aminopeptidase activity
C6I29_RS10735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C6I29_RS10740	COG3384	dioxygenase
C6I29_RS10750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6I29_RS10755	COG2878	Part of a membrane complex involved in electron transport
C6I29_RS10760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6I29_RS10785	COG0768	penicillin binding
C6I29_RS10790	COG0742	ribosomal rna small subunit methyltransferase
C6I29_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS10835	COG1253	flavin adenine dinucleotide binding
C6I29_RS10845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6I29_RS10845	COG0604	alcohol dehydrogenase
C6I29_RS10845	COG3321	synthase
C6I29_RS10845	COG4221	oxidoreductase activity
C6I29_RS10850	COG0584	glycerophosphoryl diester phosphodiesterase
C6I29_RS10880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C6I29_RS10885	COG1773	rubredoxin
C6I29_RS10890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6I29_RS10900	COG0583	DNA-binding transcription factor activity
C6I29_RS10920	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6I29_RS10925	COG4181	ATPase activity
C6I29_RS10935	COG0288	reversible hydration of carbon dioxide
C6I29_RS10970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C6I29_RS10980	COG0306	phosphate transporter
C6I29_RS11045	COG1285	pathogenesis
C6I29_RS11050	COG4681	YaeQ
C6I29_RS11055	COG0523	cobalamin synthesis protein
C6I29_RS11065	COG1607	acyl-coa hydrolase
C6I29_RS11080	COG1309	transcriptional regulator
C6I29_RS11085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6I29_RS11095	COG1741	Belongs to the pirin family
C6I29_RS11105	COG2132	Multicopper oxidase
C6I29_RS11120	COG0625	glutathione transferase activity
C6I29_RS11140	COG2031	fatty acid transporter
C6I29_RS11145	COG0183	Belongs to the thiolase family
C6I29_RS11155	COG0589	response to stress
C6I29_RS11230	COG0582	viral genome integration into host DNA
C6I29_RS11240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6I29_RS11245	COG2814	Major facilitator Superfamily
C6I29_RS11250	COG1566	PFAM secretion protein HlyD family protein
C6I29_RS11255	COG2050	protein possibly involved in aromatic compounds catabolism
C6I29_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6I29_RS11270	COG1090	epimerase
C6I29_RS11280	COG0420	3'-5' exonuclease activity
C6I29_RS11305	COG0735	belongs to the Fur family
C6I29_RS11310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6I29_RS11330	COG0121	glutamine amidotransferase
C6I29_RS11340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6I29_RS11345	COG0756	dUTP diphosphatase activity
C6I29_RS11355	COG2885	chlorophyll binding
C6I29_RS11360	COG0204	Acyl-transferase
C6I29_RS11375	COG2894	cell division
C6I29_RS11380	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C6I29_RS11390	COG1674	ftsk spoiiie
C6I29_RS11395	COG0492	ferredoxin-NADP+ reductase activity
C6I29_RS11400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C6I29_RS11410	COG0456	acetyltransferase
C6I29_RS11450	COG1981	membrane
C6I29_RS11460	COG0352	thiamine-phosphate diphosphorylase activity
C6I29_RS11460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6I29_RS11460	COG0351	phosphomethylpyrimidine kinase
C6I29_RS11465	COG1652	LysM domain
C6I29_RS11475	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS11490	COG1399	metal-binding, possibly nucleic acid-binding protein
C6I29_RS11495	COG3101	peptidyl-lysine hydroxylation
C6I29_RS11500	COG0009	L-threonylcarbamoyladenylate synthase
C6I29_RS11510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C6I29_RS11515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C6I29_RS11530	COG4106	trans-aconitate 2-methyltransferase activity
C6I29_RS11545	COG0596	Alpha beta hydrolase
C6I29_RS11545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6I29_RS11545	COG2226	methyltransferase
C6I29_RS11550	COG2193	ferroxidase activity
C6I29_RS11560	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C6I29_RS11565	COG2223	nitrite transmembrane transporter activity
C6I29_RS11570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C6I29_RS11580	COG1196	nuclear chromosome segregation
C6I29_RS11590	COG0730	response to heat
C6I29_RS11605	COG3545	Serine hydrolase
C6I29_RS11610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6I29_RS11620	COG2226	methyltransferase
C6I29_RS11625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6I29_RS11655	COG0564	pseudouridine synthase activity
C6I29_RS11695	COG1902	pentaerythritol trinitrate reductase activity
C6I29_RS11700	COG2094	Belongs to the DNA glycosylase MPG family
C6I29_RS11715	COG1970	mechanosensitive ion channel activity
C6I29_RS11720	COG1217	gtp-binding protein TYPA
C6I29_RS11725	COG2233	PERMEase
C6I29_RS11735	COG0833	amino acid
C6I29_RS11750	COG0183	Belongs to the thiolase family
C6I29_RS11790	COG1376	ErfK ybiS ycfS ynhG family protein
C6I29_RS11795	COG2832	Protein of unknown function (DUF454)
C6I29_RS11805	COG5510	response to toxic substance
C6I29_RS11810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6I29_RS11825	COG0840	transmembrane signaling receptor activity
C6I29_RS11860	COG0442	prolyl-tRNA aminoacylation
C6I29_RS11895	COG0489	protein tyrosine kinase activity
C6I29_RS11900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6I29_RS11900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6I29_RS11935	COG2081	HI0933 family
C6I29_RS11945	COG0668	transmembrane transport
C6I29_RS11965	COG0583	DNA-binding transcription factor activity
C6I29_RS11980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6I29_RS11985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6I29_RS11990	COG0713	ATP synthesis coupled electron transport
C6I29_RS12000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6I29_RS12015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6I29_RS12035	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6I29_RS12050	COG2205	protein histidine kinase activity
C6I29_RS12055	COG0745	RESPONSE REGULATOR receiver
C6I29_RS12070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6I29_RS12075	COG0583	DNA-binding transcription factor activity
C6I29_RS12080	COG4773	Receptor
C6I29_RS12095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6I29_RS12105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6I29_RS12130	COG1968	undecaprenyl-diphosphatase activity
C6I29_RS12135	COG1214	PFAM Peptidase M22, glycoprotease
C6I29_RS12140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6I29_RS12145	COG0494	nUDIX hydrolase
C6I29_RS12185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6I29_RS12195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6I29_RS12200	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C6I29_RS12205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C6I29_RS12275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C6I29_RS12290	COG0450	alkyl hydroperoxide reductase
C6I29_RS12305	COG0285	dihydrofolate synthase activity
C6I29_RS12310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C6I29_RS12355	COG4206	TonB-dependent receptor
C6I29_RS12360	COG2096	Adenosyltransferase
C6I29_RS12380	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C6I29_RS12385	COG0745	RESPONSE REGULATOR receiver
C6I29_RS12390	COG2205	protein histidine kinase activity
C6I29_RS12400	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS12405	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS12410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C6I29_RS12415	COG1162	GTPase activity
C6I29_RS12425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6I29_RS12430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C6I29_RS12435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6I29_RS12440	COG2003	Belongs to the UPF0758 family
C6I29_RS12445	COG3781	membrane
C6I29_RS12460	COG2350	Protein conserved in bacteria
C6I29_RS12480	COG1666	GTP binding
C6I29_RS12490	COG1607	acyl-coa hydrolase
C6I29_RS12515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6I29_RS12555	COG1183	phosphatidylcholine synthase activity
C6I29_RS12560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6I29_RS12590	COG0739	heme binding
C6I29_RS12590	COG0741	lytic transglycosylase activity
C6I29_RS12590	COG1196	nuclear chromosome segregation
C6I29_RS12595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C6I29_RS12600	COG1702	phosphate starvation-inducible protein PhoH
C6I29_RS12640	COG1295	ribonuclease BN
C6I29_RS12645	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6I29_RS12680	COG0557	exoribonuclease II activity
C6I29_RS12685	COG0339	signal peptide processing
C6I29_RS12690	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6I29_RS12720	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6I29_RS12725	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS12730	COG2072	flavoprotein involved in K transport
C6I29_RS12735	COG0203	ribosomal protein L17
C6I29_RS12740	COG0202	RNA polymerase activity
C6I29_RS12745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C6I29_RS12780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C6I29_RS12795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C6I29_RS12810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C6I29_RS12815	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C6I29_RS12820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C6I29_RS12835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C6I29_RS12845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C6I29_RS12855	COG0089	rRNA binding
C6I29_RS12860	COG0088	Forms part of the polypeptide exit tunnel
C6I29_RS12865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C6I29_RS12880	COG0626	cystathionine gamma-synthase activity
C6I29_RS12885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6I29_RS12885	COG1017	nitric oxide dioxygenase activity
C6I29_RS12890	COG1959	2 iron, 2 sulfur cluster binding
C6I29_RS12900	COG1301	dicarboxylic acid transport
C6I29_RS12905	COG1946	Acyl-CoA thioesterase
C6I29_RS12910	COG2937	Belongs to the GPAT DAPAT family
C6I29_RS12920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6I29_RS12925	COG1040	competence protein
C6I29_RS12940	COG0598	Magnesium transport protein CorA
C6I29_RS12950	COG2854	intermembrane phospholipid transfer
C6I29_RS12955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6I29_RS12960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6I29_RS12965	COG1127	ABC transporter
C6I29_RS12980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C6I29_RS12990	COG0408	coproporphyrinogen oxidase activity
C6I29_RS13010	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS13020	COG1983	PspC domain protein
C6I29_RS13035	COG0752	glycyl-tRNA synthetase alpha subunit
C6I29_RS13040	COG0751	glycine-tRNA ligase activity
C6I29_RS13060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6I29_RS13100	COG0628	permease
C6I29_RS13105	COG2032	superoxide dismutase activity
C6I29_RS13120	COG0277	FAD linked oxidase domain protein
C6I29_RS13125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6I29_RS13130	COG5006	permease, DMT superfamily
C6I29_RS13135	COG5006	permease, DMT superfamily
C6I29_RS13150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C6I29_RS13155	COG5380	lipid catabolic process
C6I29_RS13160	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C6I29_RS13170	COG0335	large ribosomal subunit rRNA binding
C6I29_RS13180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C6I29_RS13185	COG0228	four-way junction DNA binding
C6I29_RS13230	COG0194	GDP metabolic process
C6I29_RS13235	COG1758	RNA polymerase activity
C6I29_RS13240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6I29_RS13265	COG4969	Belongs to the N-Me-Phe pilin family
C6I29_RS13275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6I29_RS13280	COG1704	LemA family
C6I29_RS13290	COG0493	'glutamate synthase
C6I29_RS13295	COG0067	glutamate synthase
C6I29_RS13295	COG0069	glutamate synthase activity
C6I29_RS13295	COG0070	glutamate synthase
C6I29_RS13345	COG2226	methyltransferase
C6I29_RS13355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6I29_RS13360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6I29_RS13375	COG0275	rRNA processing
C6I29_RS13380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6I29_RS13390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6I29_RS13415	COG0488	(ABC) transporter
C6I29_RS13425	COG4221	oxidoreductase activity
C6I29_RS13455	COG0427	acetyl-CoA hydrolase
C6I29_RS13485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6I29_RS13500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C6I29_RS13505	COG0697	spore germination
C6I29_RS13520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6I29_RS13565	COG0582	viral genome integration into host DNA
C6I29_RS13675	COG3177	Filamentation induced by cAMP protein fic
C6I29_RS13695	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C6I29_RS13705	COG1546	Belongs to the CinA family
C6I29_RS13705	COG1058	Belongs to the CinA family
C6I29_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
C6I29_RS13730	COG0629	single-stranded DNA binding
C6I29_RS13735	COG2814	Major facilitator Superfamily
C6I29_RS13750	COG0352	thiamine-phosphate diphosphorylase activity
C6I29_RS13750	COG0351	phosphomethylpyrimidine kinase
C6I29_RS13750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6I29_RS13770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6I29_RS13790	COG3162	membrane
C6I29_RS13795	COG2205	protein histidine kinase activity
C6I29_RS13795	COG0784	Response regulator, receiver
C6I29_RS13795	COG2198	Histidine kinase
C6I29_RS13825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6I29_RS13830	COG3152	Membrane
C6I29_RS13835	COG0668	transmembrane transport
C6I29_RS13845	COG1519	Transferase
C6I29_RS13850	COG1902	pentaerythritol trinitrate reductase activity
C6I29_RS13865	COG0586	Pfam SNARE associated Golgi protein
C6I29_RS13880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6I29_RS13905	COG0426	domain, Protein
C6I29_RS13905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6I29_RS13910	COG2119	membrane
C6I29_RS13940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6I29_RS13950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6I29_RS13960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6I29_RS13970	COG2814	Major facilitator Superfamily
C6I29_RS13975	COG0189	ligase activity
C6I29_RS13985	COG0708	Exodeoxyribonuclease III
C6I29_RS14010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6I29_RS14010	COG0666	response to abiotic stimulus
C6I29_RS14030	COG3150	esterase
C6I29_RS14045	COG2918	glutathione biosynthetic process
C6I29_RS14065	COG0436	Aminotransferase
C6I29_RS14070	COG0534	Mate efflux family protein
C6I29_RS14095	COG0688	phosphatidylethanolamine metabolic process
C6I29_RS14115	COG0753	catalase activity
C6I29_RS14135	COG0560	Phosphoserine phosphatase
C6I29_RS14135	COG3830	Belongs to the UPF0237 family
C6I29_RS14155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C6I29_RS14165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6I29_RS14175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6I29_RS14180	COG0697	spore germination
C6I29_RS14185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6I29_RS14195	COG1335	isochorismatase
C6I29_RS14200	COG2814	Major facilitator Superfamily
C6I29_RS14205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6I29_RS14225	COG2155	Conserved Protein
C6I29_RS14230	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6I29_RS14235	COG2133	pyrroloquinoline quinone binding
C6I29_RS14240	COG0789	Transcriptional regulator
C6I29_RS14250	COG2983	Belongs to the UPF0260 family
C6I29_RS14255	COG5487	UPF0391 membrane protein
C6I29_RS14270	COG1194	a g-specific adenine glycosylase
C6I29_RS14285	COG2818	Glycosylase
C6I29_RS14290	COG1064	alcohol dehydrogenase
C6I29_RS14305	COG0583	DNA-binding transcription factor activity
C6I29_RS14310	COG0656	L-ascorbic acid biosynthetic process
C6I29_RS14315	COG2814	Major facilitator Superfamily
C6I29_RS14355	COG1309	transcriptional regulator
C6I29_RS14365	COG2233	PERMEase
C6I29_RS14370	COG0583	DNA-binding transcription factor activity
C6I29_RS14380	COG0546	phosphoglycolate phosphatase activity
C6I29_RS14390	COG0129	dihydroxy-acid dehydratase activity
C6I29_RS14405	COG0428	transporter
C6I29_RS14415	COG0733	neurotransmitter:sodium symporter activity
C6I29_RS14465	COG1846	Transcriptional regulator
C6I29_RS14500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6I29_RS14510	COG0657	acetylesterase activity
C6I29_RS14525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C6I29_RS14540	COG2951	lytic endotransglycosylase activity
C6I29_RS14545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6I29_RS14560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6I29_RS14565	COG0318	PFAM AMP-dependent synthetase and ligase
C6I29_RS14570	COG1960	acyl-CoA dehydrogenase activity
C6I29_RS14580	COG2814	Major facilitator Superfamily
C6I29_RS14590	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6I29_RS14605	COG0402	S-adenosylhomocysteine deaminase activity
C6I29_RS14645	COG0706	membrane insertase activity
C6I29_RS14650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C6I29_RS14655	COG0594	ribonuclease P activity