locus-tag	class	description
DOM24_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOM24_RS00010	COG0592	DNA-directed DNA polymerase activity
DOM24_RS00020	COG0187	DNA topoisomerase II activity
DOM24_RS00025	COG1063	alcohol dehydrogenase
DOM24_RS00035	COG0488	(ABC) transporter
DOM24_RS00060	COG0596	Alpha beta hydrolase
DOM24_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DOM24_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOM24_RS00085	COG1047	Peptidyl-prolyl cis-trans
DOM24_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOM24_RS00095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOM24_RS00100	COG0196	riboflavin kinase activity
DOM24_RS00120	COG1116	anion transmembrane transporter activity
DOM24_RS00125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOM24_RS00130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOM24_RS00135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DOM24_RS00140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DOM24_RS00145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DOM24_RS00145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DOM24_RS00160	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS00165	COG0546	phosphoglycolate phosphatase activity
DOM24_RS00180	COG1309	transcriptional regulator
DOM24_RS00190	COG0543	2 iron, 2 sulfur cluster binding
DOM24_RS00200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DOM24_RS00215	COG3023	N-Acetylmuramoyl-L-alanine amidase
DOM24_RS00250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DOM24_RS00265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DOM24_RS00290	COG0438	transferase activity, transferring glycosyl groups
DOM24_RS00295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DOM24_RS00305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOM24_RS00315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DOM24_RS00330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DOM24_RS00335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOM24_RS00350	COG0271	Belongs to the BolA IbaG family
DOM24_RS00365	COG0586	Pfam SNARE associated Golgi protein
DOM24_RS00370	COG0519	Catalyzes the synthesis of GMP from XMP
DOM24_RS00370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DOM24_RS00400	COG0281	malic enzyme
DOM24_RS00410	COG5632	N-Acetylmuramoyl-L-alanine amidase
DOM24_RS00410	COG3409	Peptidoglycan-binding domain 1 protein
DOM24_RS00410	COG1388	LysM domain
DOM24_RS00430	COG2837	iron assimilation
DOM24_RS00435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DOM24_RS00440	COG1121	(ABC) transporter
DOM24_RS00500	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS00515	COG0386	Belongs to the glutathione peroxidase family
DOM24_RS00530	COG0697	spore germination
DOM24_RS00540	COG0758	DNA mediated transformation
DOM24_RS00545	COG1652	LysM domain
DOM24_RS00590	COG2814	Major facilitator Superfamily
DOM24_RS00600	COG2814	Major facilitator Superfamily
DOM24_RS00620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOM24_RS00645	COG1253	flavin adenine dinucleotide binding
DOM24_RS00650	COG3012	SEC-C Motif Domain Protein
DOM24_RS00655	COG2860	membrane
DOM24_RS00660	COG0477	Major facilitator Superfamily
DOM24_RS00670	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS00685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DOM24_RS00700	COG0606	chelatase, subunit chli
DOM24_RS00710	COG0347	Belongs to the P(II) protein family
DOM24_RS00715	COG0004	ammonium transporteR
DOM24_RS00725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOM24_RS00725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOM24_RS00755	COG0795	lipopolysaccharide-transporting ATPase activity
DOM24_RS00760	COG0795	lipopolysaccharide-transporting ATPase activity
DOM24_RS00765	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOM24_RS00770	COG0793	Belongs to the peptidase S41A family
DOM24_RS00780	COG2205	protein histidine kinase activity
DOM24_RS00785	COG2197	response regulator
DOM24_RS00795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DOM24_RS00810	COG4974	Belongs to the 'phage' integrase family
DOM24_RS00835	COG0772	Belongs to the SEDS family
DOM24_RS00845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOM24_RS00850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DOM24_RS00860	COG0494	nUDIX hydrolase
DOM24_RS00895	COG3275	phosphorelay sensor kinase activity
DOM24_RS00905	COG0181	hydroxymethylbilane synthase activity
DOM24_RS00950	COG1716	ATPase activity
DOM24_RS00955	COG0546	phosphoglycolate phosphatase activity
DOM24_RS01025	COG0085	RNA polymerase activity
DOM24_RS01030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOM24_RS01045	COG2056	Na+-H+ antiporter family
DOM24_RS01055	COG0326	Molecular chaperone. Has ATPase activity
DOM24_RS01075	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DOM24_RS01105	COG0322	excinuclease ABC activity
DOM24_RS01115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOM24_RS01120	COG1132	(ABC) transporter
DOM24_RS01150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOM24_RS01160	COG0497	DNA recombination
DOM24_RS01170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOM24_RS01175	COG0697	spore germination
DOM24_RS01180	COG0237	dephospho-CoA kinase activity
DOM24_RS01225	COG0779	Required for maturation of 30S ribosomal subunits
DOM24_RS01230	COG0195	Participates in both transcription termination and antitermination
DOM24_RS01245	COG1320	monovalent cation:proton antiporter activity
DOM24_RS01250	COG2212	antiporter activity
DOM24_RS01255	COG1863	multisubunit Na H antiporter MnhE subunit
DOM24_RS01260	COG0651	ATP synthesis coupled electron transport
DOM24_RS01265	COG1006	Multisubunit Na H antiporter MnhC subunit
DOM24_RS01270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DOM24_RS01270	COG2111	Na H antiporter
DOM24_RS01285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DOM24_RS01290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DOM24_RS01320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DOM24_RS01325	COG1074	ATP-dependent DNA helicase activity
DOM24_RS01330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DOM24_RS01340	COG1185	polyribonucleotide nucleotidyltransferase activity
DOM24_RS01345	COG0598	Magnesium transport protein CorA
DOM24_RS01355	COG0484	heat shock protein binding
DOM24_RS01365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOM24_RS01375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOM24_RS01400	COG4535	Mg2 and Co2 transporter CorC
DOM24_RS01410	COG0425	Belongs to the sulfur carrier protein TusA family
DOM24_RS01420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DOM24_RS01420	COG0644	oxidoreductase
DOM24_RS01430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DOM24_RS01445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOM24_RS01460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DOM24_RS01470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DOM24_RS01470	COG0493	'glutamate synthase
DOM24_RS01485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOM24_RS01495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DOM24_RS01500	COG0534	Mate efflux family protein
DOM24_RS01510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DOM24_RS01515	COG1280	lysine exporter protein (LysE YggA)
DOM24_RS01540	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS01545	COG1530	ribonuclease E activity
DOM24_RS01560	COG0546	phosphoglycolate phosphatase activity
DOM24_RS01565	COG3971	2-oxopent-4-enoate hydratase activity
DOM24_RS01570	COG4569	acetaldehyde dehydrogenase (acetylating) activity
DOM24_RS01600	COG0583	DNA-binding transcription factor activity
DOM24_RS01605	COG4638	Rieske (2fe-2S)
DOM24_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS01625	COG3384	dioxygenase
DOM24_RS01630	COG0446	pyridine nucleotide-disulphide oxidoreductase
DOM24_RS01655	COG0753	catalase activity
DOM24_RS01665	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS01680	COG0494	nUDIX hydrolase
DOM24_RS01690	COG0583	DNA-binding transcription factor activity
DOM24_RS01695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOM24_RS01710	COG0473	3-isopropylmalate dehydrogenase activity
DOM24_RS01765	COG1560	Kdo2-lipid A biosynthetic process
DOM24_RS01775	COG0488	(ABC) transporter
DOM24_RS01780	COG2900	Belongs to the SlyX family
DOM24_RS01810	COG1929	Belongs to the glycerate kinase type-1 family
DOM24_RS01815	COG0210	DNA helicase
DOM24_RS01820	COG0724	RNA recognition motif
DOM24_RS01835	COG4651	solute:proton antiporter activity
DOM24_RS01835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DOM24_RS01860	COG0788	formyltetrahydrofolate deformylase activity
DOM24_RS01895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOM24_RS01915	COG0500	methyltransferase
DOM24_RS01980	COG2813	Specifically methylates the guanine in position
DOM24_RS01980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOM24_RS01985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOM24_RS01990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DOM24_RS02000	COG4774	siderophore transport
DOM24_RS02010	COG0740	serine-type endopeptidase activity
DOM24_RS02025	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DOM24_RS02025	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DOM24_RS02030	COG4106	trans-aconitate 2-methyltransferase activity
DOM24_RS02035	COG0857	belongs to the CobB CobQ family
DOM24_RS02035	COG0280	phosphate acetyltransferase
DOM24_RS02040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOM24_RS02055	COG2267	carboxylic ester hydrolase activity
DOM24_RS02070	COG0793	Belongs to the peptidase S41A family
DOM24_RS02105	COG1426	Protein conserved in bacteria
DOM24_RS02115	COG0124	histidyl-tRNA synthetase
DOM24_RS02125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOM24_RS02150	COG1862	Preprotein translocase
DOM24_RS02160	COG1704	LemA family
DOM24_RS02185	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DOM24_RS02205	COG0726	polysaccharide deacetylase
DOM24_RS02210	COG0463	Glycosyl transferase, family 2
DOM24_RS02215	COG0438	transferase activity, transferring glycosyl groups
DOM24_RS02240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DOM24_RS02285	COG1136	(ABC) transporter
DOM24_RS02285	COG0577	efflux transmembrane transporter activity
DOM24_RS02290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM24_RS02315	COG0028	Belongs to the TPP enzyme family
DOM24_RS02325	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DOM24_RS02335	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOM24_RS02350	COG0084	hydrolase, TatD family'
DOM24_RS02360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DOM24_RS02365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOM24_RS02375	COG2814	Major facilitator Superfamily
DOM24_RS02380	COG0697	spore germination
DOM24_RS02405	COG3622	Belongs to the hyi family
DOM24_RS02410	COG2084	Dehydrogenase
DOM24_RS02415	COG1024	Enoyl-CoA hydratase
DOM24_RS02420	COG2205	protein histidine kinase activity
DOM24_RS02420	COG0784	Response regulator, receiver
DOM24_RS02420	COG5002	protein histidine kinase activity
DOM24_RS02440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOM24_RS02450	COG3956	TIGRFAM MazG family protein
DOM24_RS02455	COG1555	photosystem II stabilization
DOM24_RS02460	COG0617	tRNA 3'-terminal CCA addition
DOM24_RS02465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DOM24_RS02475	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DOM24_RS02480	COG1660	Displays ATPase and GTPase activities
DOM24_RS02485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOM24_RS02490	COG3028	Belongs to the UPF0307 family
DOM24_RS02505	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS02525	COG0625	glutathione transferase activity
DOM24_RS02530	COG1238	metal cluster binding
DOM24_RS02570	COG0072	phenylalanine-tRNA ligase activity
DOM24_RS02595	COG0248	Ppx GppA phosphatase
DOM24_RS02605	COG0037	tRNA processing
DOM24_RS02645	COG1764	response to oxidative stress
DOM24_RS02650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DOM24_RS02700	COG2969	positive regulation of protein catabolic process
DOM24_RS02705	COG0625	glutathione transferase activity
DOM24_RS02710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DOM24_RS02725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DOM24_RS02730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DOM24_RS02735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DOM24_RS02745	COG1346	cytolysis
DOM24_RS02755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOM24_RS02765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOM24_RS02770	COG1408	metallophosphoesterase
DOM24_RS02775	COG0477	Major facilitator Superfamily
DOM24_RS02780	COG1272	protein, Hemolysin III
DOM24_RS02790	COG4667	esterase of the alpha-beta hydrolase superfamily
DOM24_RS02800	COG1250	3-hydroxyacyl-CoA dehydrogenase
DOM24_RS02800	COG1024	Enoyl-CoA hydratase
DOM24_RS02805	COG0183	Belongs to the thiolase family
DOM24_RS02810	COG2207	Transcriptional regulator
DOM24_RS02820	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOM24_RS02830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOM24_RS02840	COG1289	transmembrane transporter activity
DOM24_RS02845	COG2814	Major facilitator Superfamily
DOM24_RS02860	COG0786	glutamate:sodium symporter activity
DOM24_RS02865	COG1115	amino acid carrier protein
DOM24_RS02870	COG2059	Chromate
DOM24_RS02875	COG1752	Esterase of the alpha-beta hydrolase superfamily
DOM24_RS02895	COG4770	biotin carboxylase activity
DOM24_RS02900	COG1024	Enoyl-CoA hydratase
DOM24_RS02905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DOM24_RS02910	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS02915	COG1309	transcriptional regulator
DOM24_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS02925	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DOM24_RS02950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOM24_RS02960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOM24_RS02965	COG1077	Cell shape determining protein MreB Mrl
DOM24_RS02970	COG1792	Involved in formation and maintenance of cell shape
DOM24_RS02975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DOM24_RS02980	COG0424	maF-like protein
DOM24_RS02990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOM24_RS03000	COG0560	Phosphoserine phosphatase
DOM24_RS03020	COG0642	Histidine kinase
DOM24_RS03030	COG2194	sulfuric ester hydrolase activity
DOM24_RS03040	COG1113	amino acid transport
DOM24_RS03045	COG2828	Protein conserved in bacteria
DOM24_RS03050	COG2824	Alkylphosphonate utilization operon protein PhnA
DOM24_RS03055	COG0142	geranyltranstransferase activity
DOM24_RS03070	COG1752	Esterase of the alpha-beta hydrolase superfamily
DOM24_RS03080	COG2814	Major facilitator Superfamily
DOM24_RS03095	COG1309	transcriptional regulator
DOM24_RS03115	COG0004	ammonium transporteR
DOM24_RS03120	COG1126	abc transporter atp-binding protein
DOM24_RS03125	COG0765	amino acid transport
DOM24_RS03130	COG0765	amino acid transport
DOM24_RS03150	COG2852	Protein conserved in bacteria
DOM24_RS03160	COG0525	valine-tRNA ligase activity
DOM24_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS03180	COG0393	Putative heavy-metal-binding
DOM24_RS03185	COG1538	Outer membrane efflux protein
DOM24_RS03195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM24_RS03200	COG0671	phosphoesterase, PA-phosphatase related
DOM24_RS03215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DOM24_RS03220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DOM24_RS03225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DOM24_RS03250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM24_RS03260	COG1648	precorrin-2 dehydrogenase activity
DOM24_RS03260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DOM24_RS03265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DOM24_RS03270	COG0531	amino acid
DOM24_RS03285	COG0321	lipoyl(octanoyl) transferase activity
DOM24_RS03310	COG0586	Pfam SNARE associated Golgi protein
DOM24_RS03330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DOM24_RS03350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOM24_RS03380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DOM24_RS03395	COG0358	DNA primase activity
DOM24_RS03405	COG0564	pseudouridine synthase activity
DOM24_RS03425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DOM24_RS03475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DOM24_RS03480	COG1053	succinate dehydrogenase
DOM24_RS03500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOM24_RS03510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DOM24_RS03520	COG2354	Protein conserved in bacteria
DOM24_RS03525	COG2321	neutral zinc metallopeptidase
DOM24_RS03620	COG0110	maltose O-acetyltransferase activity
DOM24_RS03630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DOM24_RS03635	COG0505	Belongs to the CarA family
DOM24_RS03660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOM24_RS03665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DOM24_RS03700	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DOM24_RS03705	COG1597	lipid kinase activity
DOM24_RS03710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DOM24_RS03720	COG0459	protein refolding
DOM24_RS03735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOM24_RS03740	COG2239	Acts as a magnesium transporter
DOM24_RS03750	COG0501	Belongs to the peptidase M48B family
DOM24_RS03755	COG0741	lytic transglycosylase activity
DOM24_RS03755	COG1196	nuclear chromosome segregation
DOM24_RS03755	COG0739	heme binding
DOM24_RS03760	COG0037	tRNA processing
DOM24_RS03775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DOM24_RS03805	COG1215	transferase activity, transferring glycosyl groups
DOM24_RS03830	COG0439	Biotin carboxylase
DOM24_RS03845	COG0864	Transcriptional regulator
DOM24_RS03880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOM24_RS03885	COG2814	Major facilitator Superfamily
DOM24_RS03900	COG1250	3-hydroxyacyl-CoA dehydrogenase
DOM24_RS03910	COG0154	amidase activity
DOM24_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS03950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM24_RS04065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DOM24_RS04070	COG3739	integral membrane protein
DOM24_RS04085	COG3706	GGDEF domain
DOM24_RS04090	COG0302	gtp cyclohydrolase
DOM24_RS04105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DOM24_RS04110	COG0512	Glutamine amidotransferase of anthranilate synthase
DOM24_RS04115	COG0174	glutamine synthetase
DOM24_RS04130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DOM24_RS04165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DOM24_RS04170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOM24_RS04175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOM24_RS04190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DOM24_RS04200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DOM24_RS04205	COG0415	Belongs to the DNA photolyase family
DOM24_RS04215	COG1252	NADH dehydrogenase
DOM24_RS04220	COG1686	Belongs to the peptidase S11 family
DOM24_RS04260	COG1823	symporter activity
DOM24_RS04265	COG0612	Peptidase, M16
DOM24_RS04270	COG3618	amidohydrolase
DOM24_RS04285	COG3025	triphosphatase activity
DOM24_RS04295	COG0352	thiamine-phosphate diphosphorylase activity
DOM24_RS04350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOM24_RS04355	COG0076	glutamate decarboxylase activity
DOM24_RS04360	COG1522	sequence-specific DNA binding
DOM24_RS04365	COG3961	Belongs to the TPP enzyme family
DOM24_RS04370	COG1113	amino acid transport
DOM24_RS04380	COG0573	inorganic phosphate transmembrane transporter activity
DOM24_RS04390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DOM24_RS04400	COG0616	signal peptide processing
DOM24_RS04420	COG2915	High frequency lysogenization protein hflD homolog
DOM24_RS04435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DOM24_RS04440	COG1686	Belongs to the peptidase S11 family
DOM24_RS04465	COG0583	DNA-binding transcription factor activity
DOM24_RS04470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DOM24_RS04475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DOM24_RS04480	COG1067	ATP-dependent peptidase activity
DOM24_RS04525	COG1966	Carbon starvation protein
DOM24_RS04530	COG2879	small protein
DOM24_RS04535	COG0714	Associated with various cellular activities
DOM24_RS04570	COG0659	secondary active sulfate transmembrane transporter activity
DOM24_RS04580	COG2252	PERMEase
DOM24_RS04585	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DOM24_RS04595	COG1215	transferase activity, transferring glycosyl groups
DOM24_RS04605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOM24_RS04615	COG0527	aspartate kinase activity
DOM24_RS04625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DOM24_RS04640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOM24_RS04655	COG0667	Aldo Keto reductase
DOM24_RS04665	COG1765	OsmC-like protein
DOM24_RS04685	COG0540	Belongs to the ATCase OTCase family
DOM24_RS04695	COG2885	chlorophyll binding
DOM24_RS04695	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DOM24_RS04710	COG2226	methyltransferase
DOM24_RS04710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOM24_RS04710	COG0596	Alpha beta hydrolase
DOM24_RS04715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DOM24_RS04750	COG1278	Cold shock
DOM24_RS04755	COG0513	Belongs to the DEAD box helicase family
DOM24_RS04765	COG0778	Nitroreductase
DOM24_RS04795	COG1286	toxin biosynthetic process
DOM24_RS04820	COG4783	chaperone-mediated protein folding
DOM24_RS04825	COG1610	YqeY-like protein
DOM24_RS04935	COG2308	Evidence 4 Homologs of previously reported genes of
DOM24_RS04955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOM24_RS04960	COG0305	Participates in initiation and elongation during chromosome replication
DOM24_RS04970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOM24_RS04975	COG0360	Binds together with S18 to 16S ribosomal RNA
DOM24_RS04985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DOM24_RS04990	COG1845	cytochrome c oxidase, subunit III
DOM24_RS04995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DOM24_RS05000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DOM24_RS05025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DOM24_RS05045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOM24_RS05060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOM24_RS05065	COG2890	protein-(glutamine-N5) methyltransferase activity
DOM24_RS05080	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS05090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DOM24_RS05110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOM24_RS05130	COG0729	surface antigen
DOM24_RS05135	COG2911	Protein conserved in bacteria
DOM24_RS05170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOM24_RS05175	COG4605	iron ion homeostasis
DOM24_RS05180	COG4604	ABC transporter, ATP-binding protein
DOM24_RS05185	COG4607	ABC-type enterochelin transport system periplasmic component
DOM24_RS05190	COG2814	Major facilitator Superfamily
DOM24_RS05195	COG0786	glutamate:sodium symporter activity
DOM24_RS05200	COG0583	DNA-binding transcription factor activity
DOM24_RS05205	COG2707	UPF0756 membrane protein
DOM24_RS05220	COG0564	pseudouridine synthase activity
DOM24_RS05225	COG0802	atpase or kinase
DOM24_RS05230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOM24_RS05240	COG1923	regulation of RNA biosynthetic process
DOM24_RS05245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOM24_RS05260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DOM24_RS05270	COG1192	Involved in chromosome partitioning
DOM24_RS05275	COG1475	DNA binding
DOM24_RS05280	COG0811	peptide transport
DOM24_RS05290	COG1132	(ABC) transporter
DOM24_RS05295	COG1663	tetraacyldisaccharide 4'-kinase activity
DOM24_RS05315	COG0084	hydrolase, TatD family'
DOM24_RS05320	COG1309	transcriptional regulator
DOM24_RS05325	COG2165	general secretion pathway protein
DOM24_RS05380	COG0776	regulation of translation
DOM24_RS05400	COG1396	sequence-specific DNA binding
DOM24_RS05410	COG2431	L-lysine efflux transmembrane transporter activity
DOM24_RS05425	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DOM24_RS05430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DOM24_RS05435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOM24_RS05450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DOM24_RS05455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DOM24_RS05460	COG0022	dehydrogenase e1 component
DOM24_RS05465	COG0508	dehydrogenase complex catalyzes the overall conversion of
DOM24_RS05470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOM24_RS05475	COG1063	alcohol dehydrogenase
DOM24_RS05510	COG1114	Component of the transport system for branched-chain amino acids
DOM24_RS05515	COG0024	Methionine aminopeptidase
DOM24_RS05520	COG0583	DNA-binding transcription factor activity
DOM24_RS05530	COG0583	DNA-binding transcription factor activity
DOM24_RS05535	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS05540	COG2814	Major facilitator Superfamily
DOM24_RS05550	COG1585	Membrane protein implicated in regulation of membrane protease activity
DOM24_RS05560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOM24_RS05575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DOM24_RS05580	COG0569	domain protein
DOM24_RS05585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DOM24_RS05590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOM24_RS05600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DOM24_RS05610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DOM24_RS05615	COG0542	response to heat
DOM24_RS05645	COG0372	Belongs to the citrate synthase family
DOM24_RS05655	COG2204	response regulator
DOM24_RS05660	COG3852	Histidine kinase
DOM24_RS05675	COG0233	cytoplasmic translational termination
DOM24_RS05680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOM24_RS05685	COG0575	Belongs to the CDS family
DOM24_RS05700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOM24_RS05720	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOM24_RS05735	COG2137	regulation of response to DNA damage stimulus
DOM24_RS05740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOM24_RS05745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DOM24_RS05750	COG1011	Hydrolase
DOM24_RS05765	COG0268	Binds directly to 16S ribosomal RNA
DOM24_RS05770	COG0702	epimerase
DOM24_RS05775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DOM24_RS05790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOM24_RS05820	COG0316	Belongs to the HesB IscA family
DOM24_RS05825	COG0822	iron-sulfur transferase activity
DOM24_RS05850	COG0776	regulation of translation
DOM24_RS05855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOM24_RS05865	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS05870	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS05930	COG1278	Cold shock
DOM24_RS05935	COG2323	membrane
DOM24_RS05940	COG0671	phosphoesterase, PA-phosphatase related
DOM24_RS05950	COG2819	hydrolase of the alpha beta superfamily
DOM24_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS06030	COG0439	Biotin carboxylase
DOM24_RS06040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DOM24_RS06065	COG0582	viral genome integration into host DNA
DOM24_RS06215	COG1783	phage Terminase large subunit
DOM24_RS06255	COG4387	Mu-like prophage protein GP36
DOM24_RS06370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DOM24_RS06430	COG1271	oxidase subunit
DOM24_RS06435	COG1294	oxidase, subunit
DOM24_RS06450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOM24_RS06495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOM24_RS06500	COG1027	Aspartate ammonia-lyase
DOM24_RS06510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOM24_RS06520	COG1448	Aminotransferase
DOM24_RS06525	COG1113	amino acid transport
DOM24_RS06540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DOM24_RS06545	COG2814	Major facilitator Superfamily
DOM24_RS06550	COG0509	glycine decarboxylation via glycine cleavage system
DOM24_RS06565	COG1132	(ABC) transporter
DOM24_RS06570	COG2203	Gaf domain
DOM24_RS06570	COG2199	diguanylate cyclase activity
DOM24_RS06585	COG3706	GGDEF domain
DOM24_RS06590	COG3706	GGDEF domain
DOM24_RS06595	COG0668	transmembrane transport
DOM24_RS06600	COG3122	Protein conserved in bacteria
DOM24_RS06620	COG0640	Transcriptional regulator
DOM24_RS06625	COG0783	Belongs to the Dps family
DOM24_RS06650	COG0235	Class ii aldolase
DOM24_RS06660	COG1024	Enoyl-CoA hydratase
DOM24_RS06680	COG3781	membrane
DOM24_RS06690	COG2985	domain, Protein
DOM24_RS06710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM24_RS06725	COG0583	DNA-binding transcription factor activity
DOM24_RS06730	COG0477	Major facilitator Superfamily
DOM24_RS06735	COG1024	Enoyl-CoA hydratase
DOM24_RS06740	COG1024	Enoyl-CoA hydratase
DOM24_RS06745	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS06750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DOM24_RS06765	COG0583	DNA-binding transcription factor activity
DOM24_RS06775	COG3327	negative regulation of DNA-templated transcription, initiation
DOM24_RS06780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DOM24_RS06785	COG1024	Enoyl-CoA hydratase
DOM24_RS06790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOM24_RS06795	COG2151	metal-sulfur cluster biosynthetic enzyme
DOM24_RS06800	COG3396	Phenylacetate-CoA oxygenase
DOM24_RS06805	COG3460	Phenylacetate-CoA oxygenase
DOM24_RS06810	COG3396	Phenylacetate-CoA oxygenase
DOM24_RS06815	COG2030	dehydratase
DOM24_RS06815	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS06825	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DOM24_RS06830	COG4149	molybdate abc transporter
DOM24_RS06835	COG0725	ABC transporter, periplasmic molybdate-binding protein
DOM24_RS06840	COG0303	'Molybdopterin
DOM24_RS06845	COG0315	cyclic pyranopterin monophosphate synthase activity
DOM24_RS06845	COG0521	Mo-molybdopterin cofactor biosynthetic process
DOM24_RS06850	COG0314	molybdopterin synthase activity
DOM24_RS06860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DOM24_RS06870	COG0243	molybdopterin cofactor binding
DOM24_RS06875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOM24_RS06880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOM24_RS06885	COG2223	nitrite transmembrane transporter activity
DOM24_RS06915	COG1570	exodeoxyribonuclease VII activity
DOM24_RS06940	COG2814	Major facilitator Superfamily
DOM24_RS06950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DOM24_RS06960	COG2814	Major facilitator Superfamily
DOM24_RS06965	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS06970	COG0183	Belongs to the thiolase family
DOM24_RS06980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DOM24_RS06985	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS06990	COG2814	Major facilitator Superfamily
DOM24_RS06995	COG2814	Major facilitator Superfamily
DOM24_RS07005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DOM24_RS07010	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS07015	COG2814	Major facilitator Superfamily
DOM24_RS07020	COG0644	oxidoreductase
DOM24_RS07020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DOM24_RS07045	COG0583	DNA-binding transcription factor activity
DOM24_RS07050	COG1380	Effector of murein hydrolase LrgA
DOM24_RS07065	COG0406	alpha-ribazole phosphatase activity
DOM24_RS07070	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DOM24_RS07120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOM24_RS07165	COG1294	oxidase, subunit
DOM24_RS07170	COG4890	Cyd operon protein YbgT
DOM24_RS07190	COG0552	protein localization to endoplasmic reticulum
DOM24_RS07195	COG0612	Peptidase, M16
DOM24_RS07225	COG0517	IMP dehydrogenase activity
DOM24_RS07225	COG0516	GMP reductase activity
DOM24_RS07230	COG0133	tryptophan synthase activity
DOM24_RS07260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOM24_RS07285	COG0798	PFAM Bile acid sodium symporter
DOM24_RS07290	COG0640	Transcriptional regulator
DOM24_RS07345	COG1278	Cold shock
DOM24_RS07350	COG1560	Kdo2-lipid A biosynthetic process
DOM24_RS07365	COG0537	adenosine 5'-monophosphoramidase activity
DOM24_RS07390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOM24_RS07410	COG0730	response to heat
DOM24_RS07445	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DOM24_RS07450	COG0148	phosphopyruvate hydratase activity
DOM24_RS07485	COG1902	pentaerythritol trinitrate reductase activity
DOM24_RS07485	COG0446	pyridine nucleotide-disulphide oxidoreductase
DOM24_RS07500	COG0583	DNA-binding transcription factor activity
DOM24_RS07505	COG4948	Mandelate Racemase Muconate Lactonizing
DOM24_RS07510	COG4829	muconolactone delta-isomerase
DOM24_RS07520	COG4638	Rieske (2fe-2S)
DOM24_RS07525	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DOM24_RS07530	COG0543	2 iron, 2 sulfur cluster binding
DOM24_RS07530	COG0633	Ferredoxin
DOM24_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS07540	COG3135	benzoate transporter
DOM24_RS07545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DOM24_RS07550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DOM24_RS07555	COG0183	Belongs to the thiolase family
DOM24_RS07560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOM24_RS07565	COG2814	Major facilitator Superfamily
DOM24_RS07575	COG0477	Major facilitator Superfamily
DOM24_RS07580	COG0596	Alpha beta hydrolase
DOM24_RS07590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOM24_RS07610	COG2351	hydroxyisourate hydrolase activity
DOM24_RS07615	COG4772	TonB-dependent receptor
DOM24_RS07630	COG2084	Dehydrogenase
DOM24_RS07635	COG2233	PERMEase
DOM24_RS07640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM24_RS07645	COG0251	oxidation-reduction process
DOM24_RS07650	COG1335	isochorismatase
DOM24_RS07655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOM24_RS07670	COG0596	Alpha beta hydrolase
DOM24_RS07685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOM24_RS07695	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOM24_RS07705	COG0697	spore germination
DOM24_RS07730	COG0424	maF-like protein
DOM24_RS07735	COG2850	peptidyl-arginine hydroxylation
DOM24_RS07740	COG0069	glutamate synthase activity
DOM24_RS07765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOM24_RS07770	COG1454	alcohol dehydrogenase
DOM24_RS07775	COG0824	Thioesterase
DOM24_RS07780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOM24_RS07805	COG0183	Belongs to the thiolase family
DOM24_RS07820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DOM24_RS07830	COG3135	benzoate transporter
DOM24_RS07835	COG2076	Multidrug Resistance protein
DOM24_RS07850	COG0589	response to stress
DOM24_RS07855	COG0308	aminopeptidase N
DOM24_RS07875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DOM24_RS07880	COG1454	alcohol dehydrogenase
DOM24_RS07900	COG0531	amino acid
DOM24_RS07905	COG4303	Ethanolamine ammonia lyase large subunit
DOM24_RS07910	COG4302	ethanolamine ammonia-lyase activity
DOM24_RS07915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DOM24_RS07915	COG0519	Catalyzes the synthesis of GMP from XMP
DOM24_RS07920	COG2353	YceI-like domain
DOM24_RS07930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOM24_RS07965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DOM24_RS07965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOM24_RS08030	COG1464	Belongs to the NlpA lipoprotein family
DOM24_RS08035	COG1464	Belongs to the NlpA lipoprotein family
DOM24_RS08040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOM24_RS08045	COG2011	ABC-type metal ion transport system permease component
DOM24_RS08050	COG0012	GTP binding
DOM24_RS08065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DOM24_RS08080	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DOM24_RS08090	COG0386	Belongs to the glutathione peroxidase family
DOM24_RS08100	COG0436	Aminotransferase
DOM24_RS08105	COG1464	Belongs to the NlpA lipoprotein family
DOM24_RS08110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOM24_RS08115	COG2011	ABC-type metal ion transport system permease component
DOM24_RS08150	COG0242	peptide deformylase activity
DOM24_RS08165	COG0028	Belongs to the TPP enzyme family
DOM24_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS08185	COG2267	carboxylic ester hydrolase activity
DOM24_RS08195	COG2271	Major facilitator Superfamily
DOM24_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS08230	COG1414	Transcriptional regulator
DOM24_RS08235	COG4638	Rieske (2fe-2S)
DOM24_RS08240	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DOM24_RS08245	COG0543	2 iron, 2 sulfur cluster binding
DOM24_RS08245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOM24_RS08255	COG2271	Major facilitator Superfamily
DOM24_RS08260	COG2207	Transcriptional regulator
DOM24_RS08285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DOM24_RS08305	COG3052	prosthetic group binding
DOM24_RS08310	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DOM24_RS08325	COG0583	DNA-binding transcription factor activity
DOM24_RS08365	COG3706	GGDEF domain
DOM24_RS08370	COG1280	lysine exporter protein (LysE YggA)
DOM24_RS08375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM24_RS08415	COG0583	DNA-binding transcription factor activity
DOM24_RS08425	COG2814	Major facilitator Superfamily
DOM24_RS08430	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS08440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DOM24_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS08490	COG4264	IucA IucC family
DOM24_RS08495	COG4264	IucA IucC family
DOM24_RS08510	COG4264	IucA IucC family
DOM24_RS08515	COG0789	Transcriptional regulator
DOM24_RS08535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DOM24_RS08545	COG4122	O-methyltransferase activity
DOM24_RS08560	COG1739	Uncharacterized protein family UPF0029
DOM24_RS08575	COG1538	Outer membrane efflux protein
DOM24_RS08580	COG1137	ATPase activity
DOM24_RS08585	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DOM24_RS08595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DOM24_RS08615	COG1683	Conserved Protein
DOM24_RS08625	COG1228	amidohydrolase
DOM24_RS08635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOM24_RS08660	COG0830	nickel cation binding
DOM24_RS08680	COG0804	urea catabolic process
DOM24_RS08695	COG0829	nickel cation binding
DOM24_RS08705	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS08710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM24_RS08715	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS08735	COG4232	protein-disulfide reductase activity
DOM24_RS08740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOM24_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS08750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOM24_RS08755	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS08775	COG0531	amino acid
DOM24_RS08800	COG1643	Atp-dependent helicase
DOM24_RS08815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DOM24_RS08825	COG3634	alkyl hydroperoxide reductase activity
DOM24_RS08860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DOM24_RS08870	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS08875	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS08880	COG1301	dicarboxylic acid transport
DOM24_RS08895	COG3139	Protein of unknown function (DUF1315)
DOM24_RS08900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOM24_RS08905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOM24_RS08915	COG0494	nUDIX hydrolase
DOM24_RS08925	COG0642	Histidine kinase
DOM24_RS08935	COG3111	PFAM Bacterial OB fold (BOF) protein
DOM24_RS08940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DOM24_RS08945	COG2199	diguanylate cyclase activity
DOM24_RS08945	COG2203	Gaf domain
DOM24_RS08950	COG1720	tRNA m6t6A37 methyltransferase activity
DOM24_RS08960	COG0826	peptidase U32
DOM24_RS08965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DOM24_RS08970	COG3634	alkyl hydroperoxide reductase activity
DOM24_RS08990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DOM24_RS09080	COG1131	(ABC) transporter
DOM24_RS09085	COG0842	Transport permease protein
DOM24_RS09100	COG0772	Belongs to the SEDS family
DOM24_RS09105	COG2951	lytic endotransglycosylase activity
DOM24_RS09125	COG0052	Belongs to the universal ribosomal protein uS2 family
DOM24_RS09130	COG0024	Methionine aminopeptidase
DOM24_RS09145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOM24_RS09150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DOM24_RS09165	COG2391	methyltransferase activity
DOM24_RS09200	COG3706	GGDEF domain
DOM24_RS09205	COG1253	flavin adenine dinucleotide binding
DOM24_RS09230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOM24_RS09260	COG3040	lipid binding
DOM24_RS09265	COG0556	nucleotide-excision repair
DOM24_RS09275	COG2199	diguanylate cyclase activity
DOM24_RS09280	COG0436	Aminotransferase
DOM24_RS09310	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DOM24_RS09315	COG1381	Involved in DNA repair and RecF pathway recombination
DOM24_RS09325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOM24_RS09330	COG0571	ribonuclease III activity
DOM24_RS09340	COG0681	Belongs to the peptidase S26 family
DOM24_RS09355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOM24_RS09370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOM24_RS09375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOM24_RS09380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DOM24_RS09390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DOM24_RS09395	COG4208	sulfate ABC transporter
DOM24_RS09400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DOM24_RS09405	COG0583	DNA-binding transcription factor activity
DOM24_RS09420	COG0602	queuosine metabolic process
DOM24_RS09425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DOM24_RS09435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DOM24_RS09440	COG1056	cytidyltransferase-related domain
DOM24_RS09440	COG1051	belongs to the nudix hydrolase family
DOM24_RS09445	COG1024	Enoyl-CoA hydratase
DOM24_RS09460	COG0300	oxidoreductase activity
DOM24_RS09465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOM24_RS09465	COG0047	phosphoribosylformylglycinamidine synthase activity
DOM24_RS09480	COG2255	four-way junction helicase activity
DOM24_RS09485	COG2072	flavoprotein involved in K transport
DOM24_RS09500	COG0824	Thioesterase
DOM24_RS09520	COG0823	Involved in the tonB-independent uptake of proteins
DOM24_RS09540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOM24_RS09580	COG0628	permease
DOM24_RS09585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DOM24_RS09590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOM24_RS09610	COG2333	competence protein COMEC
DOM24_RS09610	COG0658	competence protein
DOM24_RS09615	COG1136	(ABC) transporter
DOM24_RS09635	COG1671	Belongs to the UPF0178 family
DOM24_RS09655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOM24_RS09685	COG1280	lysine exporter protein (LysE YggA)
DOM24_RS09705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOM24_RS09710	COG0019	diaminopimelate decarboxylase activity
DOM24_RS09720	COG1113	amino acid transport
DOM24_RS09745	COG0174	glutamine synthetase
DOM24_RS09750	COG0745	RESPONSE REGULATOR receiver
DOM24_RS09765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DOM24_RS09770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DOM24_RS09780	COG0833	amino acid
DOM24_RS09790	COG3724	N-succinylarginine dihydrolase activity
DOM24_RS09795	COG1012	belongs to the aldehyde dehydrogenase family
DOM24_RS09800	COG3138	arginine N-succinyltransferase
DOM24_RS09805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DOM24_RS09810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOM24_RS09825	COG1902	pentaerythritol trinitrate reductase activity
DOM24_RS09825	COG0446	pyridine nucleotide-disulphide oxidoreductase
DOM24_RS09830	COG0277	FAD linked oxidase domain protein
DOM24_RS09840	COG2186	Transcriptional regulator
DOM24_RS09855	COG3706	GGDEF domain
DOM24_RS09855	COG2203	Gaf domain
DOM24_RS09855	COG5001	Diguanylate cyclase
DOM24_RS09855	COG4251	negative regulation of phosphorylation
DOM24_RS09860	COG0418	dihydroorotase activity
DOM24_RS09865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DOM24_RS09880	COG0833	amino acid
DOM24_RS09905	COG4172	Belongs to the ABC transporter superfamily
DOM24_RS09910	COG4239	(ABC) transporter, permease
DOM24_RS09915	COG4174	ABC transporter (Permease)
DOM24_RS09920	COG4166	transmembrane transport
DOM24_RS09925	COG0741	lytic transglycosylase activity
DOM24_RS09925	COG0741	lytic transglycosylase activity
DOM24_RS09925	COG1388	LysM domain
DOM24_RS09925	COG1388	LysM domain
DOM24_RS09930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DOM24_RS09940	COG2816	NAD+ diphosphatase activity
DOM24_RS09960	COG3107	peptidoglycan biosynthetic process
DOM24_RS09975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOM24_RS09980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOM24_RS09985	COG0006	proline dipeptidase activity
DOM24_RS10010	COG1522	sequence-specific DNA binding
DOM24_RS10030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOM24_RS10035	COG2169	Transcriptional regulator
DOM24_RS10035	COG1917	Cupin 2, conserved barrel domain protein
DOM24_RS10045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOM24_RS10055	COG2234	aminopeptidase activity
DOM24_RS10060	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOM24_RS10065	COG3384	dioxygenase
DOM24_RS10075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOM24_RS10080	COG2878	Part of a membrane complex involved in electron transport
DOM24_RS10085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOM24_RS10110	COG0768	penicillin binding
DOM24_RS10115	COG0742	ribosomal rna small subunit methyltransferase
DOM24_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS10160	COG1253	flavin adenine dinucleotide binding
DOM24_RS10170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOM24_RS10170	COG3321	synthase
DOM24_RS10170	COG4221	oxidoreductase activity
DOM24_RS10170	COG0604	alcohol dehydrogenase
DOM24_RS10175	COG0584	glycerophosphoryl diester phosphodiesterase
DOM24_RS10205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOM24_RS10210	COG1773	rubredoxin
DOM24_RS10215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOM24_RS10225	COG0583	DNA-binding transcription factor activity
DOM24_RS10245	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DOM24_RS10250	COG4181	ATPase activity
DOM24_RS10260	COG0288	reversible hydration of carbon dioxide
DOM24_RS10295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DOM24_RS10305	COG0306	phosphate transporter
DOM24_RS10320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOM24_RS10325	COG0477	Major facilitator Superfamily
DOM24_RS10340	COG0477	Major facilitator Superfamily
DOM24_RS10370	COG1285	pathogenesis
DOM24_RS10375	COG4681	YaeQ
DOM24_RS10380	COG0523	cobalamin synthesis protein
DOM24_RS10390	COG1607	acyl-coa hydrolase
DOM24_RS10405	COG1309	transcriptional regulator
DOM24_RS10410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DOM24_RS10420	COG1741	Belongs to the pirin family
DOM24_RS10430	COG2132	Multicopper oxidase
DOM24_RS10445	COG0625	glutathione transferase activity
DOM24_RS10465	COG2031	fatty acid transporter
DOM24_RS10470	COG0183	Belongs to the thiolase family
DOM24_RS10480	COG0589	response to stress
DOM24_RS10505	COG0154	amidase activity
DOM24_RS10510	COG0477	Major facilitator Superfamily
DOM24_RS10515	COG1522	sequence-specific DNA binding
DOM24_RS10550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DOM24_RS10555	COG1335	isochorismatase
DOM24_RS10600	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DOM24_RS10600	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DOM24_RS10625	COG0514	ATP-dependent DNA helicase (RecQ)
DOM24_RS10705	COG0582	viral genome integration into host DNA
DOM24_RS10730	COG3179	chitinase
DOM24_RS10845	COG4695	Portal protein
DOM24_RS10900	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DOM24_RS10940	COG0305	Participates in initiation and elongation during chromosome replication
DOM24_RS11030	COG0582	viral genome integration into host DNA
DOM24_RS11040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOM24_RS11045	COG2814	Major facilitator Superfamily
DOM24_RS11050	COG1566	PFAM secretion protein HlyD family protein
DOM24_RS11060	COG2050	protein possibly involved in aromatic compounds catabolism
DOM24_RS11070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOM24_RS11075	COG1090	epimerase
DOM24_RS11085	COG0420	3'-5' exonuclease activity
DOM24_RS11110	COG0735	belongs to the Fur family
DOM24_RS11115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOM24_RS11135	COG0121	glutamine amidotransferase
DOM24_RS11145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOM24_RS11150	COG0756	dUTP diphosphatase activity
DOM24_RS11160	COG2885	chlorophyll binding
DOM24_RS11165	COG0204	Acyl-transferase
DOM24_RS11180	COG2894	cell division
DOM24_RS11185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DOM24_RS11195	COG1674	ftsk spoiiie
DOM24_RS11200	COG0492	ferredoxin-NADP+ reductase activity
DOM24_RS11205	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DOM24_RS11255	COG1981	membrane
DOM24_RS11265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DOM24_RS11265	COG0352	thiamine-phosphate diphosphorylase activity
DOM24_RS11265	COG0351	phosphomethylpyrimidine kinase
DOM24_RS11270	COG1652	LysM domain
DOM24_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS11295	COG1399	metal-binding, possibly nucleic acid-binding protein
DOM24_RS11300	COG3101	peptidyl-lysine hydroxylation
DOM24_RS11305	COG0009	L-threonylcarbamoyladenylate synthase
DOM24_RS11315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOM24_RS11320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOM24_RS11335	COG4106	trans-aconitate 2-methyltransferase activity
DOM24_RS11350	COG0596	Alpha beta hydrolase
DOM24_RS11355	COG2193	ferroxidase activity
DOM24_RS11365	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DOM24_RS11370	COG2223	nitrite transmembrane transporter activity
DOM24_RS11375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOM24_RS11385	COG1196	nuclear chromosome segregation
DOM24_RS11395	COG0730	response to heat
DOM24_RS11415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOM24_RS11425	COG2226	methyltransferase
DOM24_RS11430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOM24_RS11460	COG0564	pseudouridine synthase activity
DOM24_RS11490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DOM24_RS11505	COG1902	pentaerythritol trinitrate reductase activity
DOM24_RS11510	COG2094	Belongs to the DNA glycosylase MPG family
DOM24_RS11520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOM24_RS11525	COG1970	mechanosensitive ion channel activity
DOM24_RS11530	COG1217	gtp-binding protein TYPA
DOM24_RS11535	COG2233	PERMEase
DOM24_RS11545	COG0833	amino acid
DOM24_RS11560	COG0183	Belongs to the thiolase family
DOM24_RS11600	COG1376	ErfK ybiS ycfS ynhG family protein
DOM24_RS11605	COG2832	Protein of unknown function (DUF454)
DOM24_RS11615	COG5510	response to toxic substance
DOM24_RS11620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOM24_RS11630	COG2198	Histidine kinase
DOM24_RS11630	COG0643	Histidine kinase
DOM24_RS11635	COG0840	transmembrane signaling receptor activity
DOM24_RS11670	COG0442	prolyl-tRNA aminoacylation
DOM24_RS11705	COG0489	protein tyrosine kinase activity
DOM24_RS11710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOM24_RS11710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOM24_RS11745	COG2081	HI0933 family
DOM24_RS11755	COG0668	transmembrane transport
DOM24_RS11770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOM24_RS11775	COG0583	DNA-binding transcription factor activity
DOM24_RS11790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOM24_RS11795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DOM24_RS11800	COG0713	ATP synthesis coupled electron transport
DOM24_RS11810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOM24_RS11825	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DOM24_RS11845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOM24_RS11860	COG2205	protein histidine kinase activity
DOM24_RS11865	COG0745	RESPONSE REGULATOR receiver
DOM24_RS11880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOM24_RS11885	COG5290	Psort location Cytoplasmic, score
DOM24_RS11950	COG0583	DNA-binding transcription factor activity
DOM24_RS11955	COG4773	Receptor
DOM24_RS11970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOM24_RS11980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DOM24_RS12005	COG1968	undecaprenyl-diphosphatase activity
DOM24_RS12010	COG1214	PFAM Peptidase M22, glycoprotease
DOM24_RS12015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DOM24_RS12020	COG0494	nUDIX hydrolase
DOM24_RS12060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOM24_RS12070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DOM24_RS12075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DOM24_RS12080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOM24_RS12150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DOM24_RS12165	COG0450	alkyl hydroperoxide reductase
DOM24_RS12180	COG0285	dihydrofolate synthase activity
DOM24_RS12185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOM24_RS12230	COG4206	TonB-dependent receptor
DOM24_RS12235	COG2096	Adenosyltransferase
DOM24_RS12260	COG0745	RESPONSE REGULATOR receiver
DOM24_RS12265	COG2205	protein histidine kinase activity
DOM24_RS12275	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS12280	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS12285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DOM24_RS12290	COG1162	GTPase activity
DOM24_RS12300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DOM24_RS12305	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DOM24_RS12310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOM24_RS12315	COG2003	Belongs to the UPF0758 family
DOM24_RS12320	COG3781	membrane
DOM24_RS12335	COG2350	Protein conserved in bacteria
DOM24_RS12355	COG1666	GTP binding
DOM24_RS12365	COG1607	acyl-coa hydrolase
DOM24_RS12430	COG1183	phosphatidylcholine synthase activity
DOM24_RS12435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DOM24_RS12465	COG0739	heme binding
DOM24_RS12465	COG1196	nuclear chromosome segregation
DOM24_RS12465	COG0741	lytic transglycosylase activity
DOM24_RS12470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOM24_RS12475	COG1702	phosphate starvation-inducible protein PhoH
DOM24_RS12515	COG1295	ribonuclease BN
DOM24_RS12555	COG0557	exoribonuclease II activity
DOM24_RS12560	COG0339	signal peptide processing
DOM24_RS12565	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DOM24_RS12595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DOM24_RS12600	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS12605	COG2072	flavoprotein involved in K transport
DOM24_RS12610	COG0203	ribosomal protein L17
DOM24_RS12615	COG0202	RNA polymerase activity
DOM24_RS12620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOM24_RS12655	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOM24_RS12670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOM24_RS12685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOM24_RS12690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOM24_RS12695	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOM24_RS12710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOM24_RS12720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOM24_RS12730	COG0089	rRNA binding
DOM24_RS12735	COG0088	Forms part of the polypeptide exit tunnel
DOM24_RS12740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOM24_RS12755	COG0626	cystathionine gamma-synthase activity
DOM24_RS12760	COG1017	nitric oxide dioxygenase activity
DOM24_RS12760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOM24_RS12765	COG1959	2 iron, 2 sulfur cluster binding
DOM24_RS12775	COG1301	dicarboxylic acid transport
DOM24_RS12780	COG1946	Acyl-CoA thioesterase
DOM24_RS12785	COG2937	Belongs to the GPAT DAPAT family
DOM24_RS12795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOM24_RS12800	COG1040	competence protein
DOM24_RS12815	COG0598	Magnesium transport protein CorA
DOM24_RS12825	COG2854	intermembrane phospholipid transfer
DOM24_RS12830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DOM24_RS12835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DOM24_RS12840	COG1127	ABC transporter
DOM24_RS12855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOM24_RS12865	COG0408	coproporphyrinogen oxidase activity
DOM24_RS12885	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS12895	COG1983	PspC domain protein
DOM24_RS12910	COG0752	glycyl-tRNA synthetase alpha subunit
DOM24_RS12915	COG0751	glycine-tRNA ligase activity
DOM24_RS12935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOM24_RS12975	COG0628	permease
DOM24_RS12980	COG2032	superoxide dismutase activity
DOM24_RS12995	COG0277	FAD linked oxidase domain protein
DOM24_RS13000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DOM24_RS13005	COG5006	permease, DMT superfamily
DOM24_RS13010	COG5006	permease, DMT superfamily
DOM24_RS13025	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOM24_RS13030	COG5380	lipid catabolic process
DOM24_RS13035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DOM24_RS13045	COG0335	large ribosomal subunit rRNA binding
DOM24_RS13055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOM24_RS13060	COG0228	four-way junction DNA binding
DOM24_RS13105	COG0194	GDP metabolic process
DOM24_RS13110	COG1758	RNA polymerase activity
DOM24_RS13115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOM24_RS13165	COG0463	Glycosyl transferase, family 2
DOM24_RS13185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DOM24_RS13190	COG1704	LemA family
DOM24_RS13200	COG0493	'glutamate synthase
DOM24_RS13205	COG0069	glutamate synthase activity
DOM24_RS13205	COG0067	glutamate synthase
DOM24_RS13205	COG0070	glutamate synthase
DOM24_RS13255	COG2226	methyltransferase
DOM24_RS13265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DOM24_RS13270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOM24_RS13285	COG0275	rRNA processing
DOM24_RS13290	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DOM24_RS13300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOM24_RS13325	COG0488	(ABC) transporter
DOM24_RS13335	COG4221	oxidoreductase activity
DOM24_RS13365	COG0427	acetyl-CoA hydrolase
DOM24_RS13395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DOM24_RS13410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DOM24_RS13415	COG0697	spore germination
DOM24_RS13430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DOM24_RS13435	COG0107	imidazoleglycerol-phosphate synthase activity
DOM24_RS13490	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DOM24_RS13500	COG1058	Belongs to the CinA family
DOM24_RS13500	COG1546	Belongs to the CinA family
DOM24_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
DOM24_RS13525	COG0629	single-stranded DNA binding
DOM24_RS13530	COG2814	Major facilitator Superfamily
DOM24_RS13545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DOM24_RS13545	COG0352	thiamine-phosphate diphosphorylase activity
DOM24_RS13545	COG0351	phosphomethylpyrimidine kinase
DOM24_RS13565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DOM24_RS13585	COG3162	membrane
DOM24_RS13590	COG2205	protein histidine kinase activity
DOM24_RS13590	COG2198	Histidine kinase
DOM24_RS13590	COG0784	Response regulator, receiver
DOM24_RS13620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DOM24_RS13625	COG3152	Membrane
DOM24_RS13630	COG0668	transmembrane transport
DOM24_RS13640	COG1519	Transferase
DOM24_RS13645	COG1902	pentaerythritol trinitrate reductase activity
DOM24_RS13660	COG0586	Pfam SNARE associated Golgi protein
DOM24_RS13675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DOM24_RS13700	COG0426	domain, Protein
DOM24_RS13700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOM24_RS13705	COG2119	membrane
DOM24_RS13735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOM24_RS13745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DOM24_RS13755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DOM24_RS13770	COG0189	ligase activity
DOM24_RS13780	COG0708	Exodeoxyribonuclease III
DOM24_RS13805	COG0666	response to abiotic stimulus
DOM24_RS13805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DOM24_RS13825	COG3150	esterase
DOM24_RS13840	COG2918	glutathione biosynthetic process
DOM24_RS13860	COG0436	Aminotransferase
DOM24_RS13865	COG0534	Mate efflux family protein
DOM24_RS13890	COG0688	phosphatidylethanolamine metabolic process
DOM24_RS13910	COG0753	catalase activity
DOM24_RS13930	COG3830	Belongs to the UPF0237 family
DOM24_RS13930	COG0560	Phosphoserine phosphatase
DOM24_RS13945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DOM24_RS13950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOM24_RS13960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DOM24_RS13970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DOM24_RS14030	COG0697	spore germination
DOM24_RS14035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOM24_RS14040	COG0385	Bile acid
DOM24_RS14045	COG1335	isochorismatase
DOM24_RS14050	COG2814	Major facilitator Superfamily
DOM24_RS14055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOM24_RS14075	COG2155	Conserved Protein
DOM24_RS14080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DOM24_RS14085	COG2133	pyrroloquinoline quinone binding
DOM24_RS14090	COG0789	Transcriptional regulator
DOM24_RS14100	COG2983	Belongs to the UPF0260 family
DOM24_RS14105	COG5487	UPF0391 membrane protein
DOM24_RS14120	COG1194	a g-specific adenine glycosylase
DOM24_RS14135	COG2818	Glycosylase
DOM24_RS14140	COG1064	alcohol dehydrogenase
DOM24_RS14155	COG0583	DNA-binding transcription factor activity
DOM24_RS14160	COG0656	L-ascorbic acid biosynthetic process
DOM24_RS14165	COG2814	Major facilitator Superfamily
DOM24_RS14205	COG1309	transcriptional regulator
DOM24_RS14215	COG2233	PERMEase
DOM24_RS14220	COG0583	DNA-binding transcription factor activity
DOM24_RS14230	COG0546	phosphoglycolate phosphatase activity
DOM24_RS14240	COG0129	dihydroxy-acid dehydratase activity
DOM24_RS14255	COG0428	transporter
DOM24_RS14265	COG0733	neurotransmitter:sodium symporter activity
DOM24_RS14315	COG1846	Transcriptional regulator
DOM24_RS14350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOM24_RS14360	COG0657	acetylesterase activity
DOM24_RS14375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOM24_RS14390	COG2951	lytic endotransglycosylase activity
DOM24_RS14395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOM24_RS14410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DOM24_RS14415	COG0318	PFAM AMP-dependent synthetase and ligase
DOM24_RS14420	COG1960	acyl-CoA dehydrogenase activity
DOM24_RS14430	COG2814	Major facilitator Superfamily
DOM24_RS14440	COG1250	3-hydroxyacyl-CoA dehydrogenase
DOM24_RS14455	COG0402	S-adenosylhomocysteine deaminase activity
DOM24_RS14475	COG1230	cation diffusion facilitator family transporter
DOM24_RS14495	COG0706	membrane insertase activity
DOM24_RS14500	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DOM24_RS14505	COG0594	ribonuclease P activity