locus-tag	class	description
FSC10_RS00010	COG0592	DNA-directed DNA polymerase activity
FSC10_RS00020	COG0187	DNA topoisomerase II activity
FSC10_RS00030	COG1063	alcohol dehydrogenase
FSC10_RS00035	COG0488	(ABC) transporter
FSC10_RS00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSC10_RS00130	COG2814	Major facilitator Superfamily
FSC10_RS00135	COG2814	Major facilitator Superfamily
FSC10_RS00150	COG0693	protein deglycase activity
FSC10_RS00160	COG1012	belongs to the aldehyde dehydrogenase family
FSC10_RS00165	COG0733	neurotransmitter:sodium symporter activity
FSC10_RS00175	COG0428	transporter
FSC10_RS00180	COG3293	Transposase
FSC10_RS00205	COG0129	dihydroxy-acid dehydratase activity
FSC10_RS00230	COG2233	PERMEase
FSC10_RS00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC10_RS00265	COG0783	Belongs to the Dps family
FSC10_RS00275	COG0675	Transposase, IS605 OrfB family
FSC10_RS00290	COG2814	Major facilitator Superfamily
FSC10_RS00295	COG0656	L-ascorbic acid biosynthetic process
FSC10_RS00300	COG0583	DNA-binding transcription factor activity
FSC10_RS00305	COG1064	alcohol dehydrogenase
FSC10_RS00310	COG2818	Glycosylase
FSC10_RS00325	COG1194	a g-specific adenine glycosylase
FSC10_RS00340	COG0545	Peptidyl-prolyl cis-trans isomerase
FSC10_RS00365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FSC10_RS00380	COG0438	transferase activity, transferring glycosyl groups
FSC10_RS00405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC10_RS00415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSC10_RS00425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSC10_RS00440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC10_RS00445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC10_RS00490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSC10_RS00500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FSC10_RS00505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FSC10_RS00510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSC10_RS00535	COG0589	response to stress
FSC10_RS00540	COG2072	flavoprotein involved in K transport
FSC10_RS00545	COG0492	ferredoxin-NADP+ reductase activity
FSC10_RS00550	COG0431	NADPH-dependent FMN reductase
FSC10_RS00555	COG0798	PFAM Bile acid sodium symporter
FSC10_RS00565	COG0640	Transcriptional regulator
FSC10_RS00670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC10_RS00675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC10_RS00710	COG4628	conserved protein (DUF2132)
FSC10_RS00795	COG3756	Protein conserved in bacteria
FSC10_RS00840	COG1192	Involved in chromosome partitioning
FSC10_RS00855	COG0586	Pfam SNARE associated Golgi protein
FSC10_RS00860	COG2259	Doxx family
FSC10_RS00870	COG0519	Catalyzes the synthesis of GMP from XMP
FSC10_RS00870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC10_RS00875	COG3706	GGDEF domain
FSC10_RS00880	COG3706	GGDEF domain
FSC10_RS00935	COG0534	Mate efflux family protein
FSC10_RS00940	COG0436	Aminotransferase
FSC10_RS00945	COG3501	Rhs element vgr protein
FSC10_RS00960	COG2837	iron assimilation
FSC10_RS00970	COG3123	guanosine phosphorylase activity
FSC10_RS00975	COG1683	Conserved Protein
FSC10_RS00980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSC10_RS00985	COG1121	(ABC) transporter
FSC10_RS01035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSC10_RS01045	COG1012	belongs to the aldehyde dehydrogenase family
FSC10_RS01060	COG0386	Belongs to the glutathione peroxidase family
FSC10_RS01065	COG0697	spore germination
FSC10_RS01075	COG0758	DNA mediated transformation
FSC10_RS01125	COG2814	Major facilitator Superfamily
FSC10_RS01145	COG0477	Major facilitator Superfamily
FSC10_RS01150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC10_RS01185	COG1253	flavin adenine dinucleotide binding
FSC10_RS01195	COG2860	membrane
FSC10_RS01200	COG0477	Major facilitator Superfamily
FSC10_RS01210	COG0318	PFAM AMP-dependent synthetase and ligase
FSC10_RS01225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSC10_RS01250	COG0606	chelatase, subunit chli
FSC10_RS01260	COG0347	Belongs to the P(II) protein family
FSC10_RS01265	COG0004	ammonium transporteR
FSC10_RS01275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC10_RS01275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC10_RS01290	COG0586	Pfam SNARE associated Golgi protein
FSC10_RS01310	COG0795	lipopolysaccharide-transporting ATPase activity
FSC10_RS01315	COG0795	lipopolysaccharide-transporting ATPase activity
FSC10_RS01320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSC10_RS01325	COG0793	Belongs to the peptidase S41A family
FSC10_RS01335	COG5002	protein histidine kinase activity
FSC10_RS01340	COG2197	response regulator
FSC10_RS01350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSC10_RS01360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC10_RS01365	COG4974	Belongs to the 'phage' integrase family
FSC10_RS01390	COG0772	Belongs to the SEDS family
FSC10_RS01400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC10_RS01405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSC10_RS01410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSC10_RS01415	COG0494	nUDIX hydrolase
FSC10_RS01420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FSC10_RS01430	COG1538	Outer membrane efflux protein
FSC10_RS01445	COG1132	(ABC) transporter
FSC10_RS01455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSC10_RS01465	COG0497	DNA recombination
FSC10_RS01470	COG3123	guanosine phosphorylase activity
FSC10_RS01475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC10_RS01485	COG0237	dephospho-CoA kinase activity
FSC10_RS01510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FSC10_RS01540	COG0779	Required for maturation of 30S ribosomal subunits
FSC10_RS01545	COG0195	Participates in both transcription termination and antitermination
FSC10_RS01555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSC10_RS01565	COG2212	antiporter activity
FSC10_RS01570	COG1863	multisubunit Na H antiporter MnhE subunit
FSC10_RS01575	COG0651	ATP synthesis coupled electron transport
FSC10_RS01580	COG1006	Multisubunit Na H antiporter MnhC subunit
FSC10_RS01585	COG2111	Na H antiporter
FSC10_RS01585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC10_RS01600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSC10_RS01605	COG4221	oxidoreductase activity
FSC10_RS01615	COG0488	(ABC) transporter
FSC10_RS01655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC10_RS01675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSC10_RS01680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSC10_RS01685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSC10_RS01690	COG2226	methyltransferase
FSC10_RS01740	COG0067	glutamate synthase
FSC10_RS01740	COG0070	glutamate synthase
FSC10_RS01740	COG0069	glutamate synthase activity
FSC10_RS01745	COG0493	'glutamate synthase
FSC10_RS01750	COG1704	LemA family
FSC10_RS01785	COG3307	-O-antigen
FSC10_RS01805	COG0675	Transposase, IS605 OrfB family
FSC10_RS01810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC10_RS01815	COG1758	RNA polymerase activity
FSC10_RS01820	COG0194	GDP metabolic process
FSC10_RS01825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FSC10_RS01870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSC10_RS01880	COG0335	large ribosomal subunit rRNA binding
FSC10_RS01895	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC10_RS01900	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC10_RS01905	COG5380	lipid catabolic process
FSC10_RS01910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSC10_RS01930	COG5006	permease, DMT superfamily
FSC10_RS01935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSC10_RS01940	COG0277	FAD linked oxidase domain protein
FSC10_RS01955	COG2814	Major facilitator Superfamily
FSC10_RS01965	COG0628	permease
FSC10_RS01985	COG2226	methyltransferase
FSC10_RS02000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSC10_RS02005	COG0254	rRNA binding
FSC10_RS02010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC10_RS02025	COG0534	Mate efflux family protein
FSC10_RS02035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC10_RS02045	COG1278	Cold shock
FSC10_RS02050	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS02065	COG0408	coproporphyrinogen oxidase activity
FSC10_RS02070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC10_RS02095	COG1127	ABC transporter
FSC10_RS02100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSC10_RS02105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSC10_RS02110	COG2854	intermembrane phospholipid transfer
FSC10_RS02120	COG0598	Magnesium transport protein CorA
FSC10_RS02130	COG0494	nUDIX hydrolase
FSC10_RS02135	COG1040	competence protein
FSC10_RS02140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSC10_RS02150	COG2937	Belongs to the GPAT DAPAT family
FSC10_RS02155	COG1946	Acyl-CoA thioesterase
FSC10_RS02160	COG1301	dicarboxylic acid transport
FSC10_RS02180	COG1959	2 iron, 2 sulfur cluster binding
FSC10_RS02190	COG0433	COG0433 Predicted ATPase
FSC10_RS02195	COG0626	cystathionine gamma-synthase activity
FSC10_RS02215	COG0088	Forms part of the polypeptide exit tunnel
FSC10_RS02220	COG0089	rRNA binding
FSC10_RS02230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FSC10_RS02280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSC10_RS02285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSC10_RS02295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSC10_RS02320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSC10_RS02330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSC10_RS02335	COG0202	RNA polymerase activity
FSC10_RS02340	COG0203	ribosomal protein L17
FSC10_RS02345	COG2072	flavoprotein involved in K transport
FSC10_RS02350	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS02355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FSC10_RS02390	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FSC10_RS02395	COG0339	signal peptide processing
FSC10_RS02405	COG0557	exoribonuclease II activity
FSC10_RS02440	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSC10_RS02455	COG1295	ribonuclease BN
FSC10_RS02520	COG1702	phosphate starvation-inducible protein PhoH
FSC10_RS02525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSC10_RS02530	COG1196	nuclear chromosome segregation
FSC10_RS02530	COG0741	lytic transglycosylase activity
FSC10_RS02530	COG0739	heme binding
FSC10_RS02570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FSC10_RS02575	COG1183	phosphatidylcholine synthase activity
FSC10_RS02640	COG1607	acyl-coa hydrolase
FSC10_RS02670	COG2350	Protein conserved in bacteria
FSC10_RS02690	COG3781	membrane
FSC10_RS02695	COG2003	Belongs to the UPF0758 family
FSC10_RS02700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSC10_RS02710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSC10_RS02720	COG2814	Major facilitator Superfamily
FSC10_RS02740	COG0004	ammonium transporteR
FSC10_RS02755	COG3622	Belongs to the hyi family
FSC10_RS02760	COG2084	Dehydrogenase
FSC10_RS02765	COG1024	Enoyl-CoA hydratase
FSC10_RS02770	COG0784	Response regulator, receiver
FSC10_RS02770	COG2205	protein histidine kinase activity
FSC10_RS02770	COG5002	protein histidine kinase activity
FSC10_RS02775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC10_RS02790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC10_RS02800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSC10_RS02810	COG1862	Preprotein translocase
FSC10_RS02825	COG1704	LemA family
FSC10_RS02835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSC10_RS02865	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS02870	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS02880	COG2205	protein histidine kinase activity
FSC10_RS02885	COG0745	RESPONSE REGULATOR receiver
FSC10_RS02890	COG1113	amino acid transport
FSC10_RS02920	COG2096	Adenosyltransferase
FSC10_RS02925	COG4206	TonB-dependent receptor
FSC10_RS02960	COG0159	tryptophan synthase activity
FSC10_RS02970	COG0285	dihydrofolate synthase activity
FSC10_RS02985	COG0450	alkyl hydroperoxide reductase
FSC10_RS03000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSC10_RS03005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSC10_RS03075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSC10_RS03080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSC10_RS03125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC10_RS03130	COG1408	metallophosphoesterase
FSC10_RS03140	COG0477	Major facilitator Superfamily
FSC10_RS03145	COG1272	protein, Hemolysin III
FSC10_RS03155	COG2153	protein acetylation
FSC10_RS03165	COG1024	Enoyl-CoA hydratase
FSC10_RS03165	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC10_RS03170	COG0183	Belongs to the thiolase family
FSC10_RS03175	COG2207	Transcriptional regulator
FSC10_RS03185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC10_RS03200	COG0183	Belongs to the thiolase family
FSC10_RS03220	COG0833	amino acid
FSC10_RS03230	COG2233	PERMEase
FSC10_RS03245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC10_RS03260	COG1902	pentaerythritol trinitrate reductase activity
FSC10_RS03280	COG0354	folic acid binding
FSC10_RS03285	COG2132	Multicopper oxidase
FSC10_RS03350	COG0564	pseudouridine synthase activity
FSC10_RS03365	COG2824	Alkylphosphonate utilization operon protein PhnA
FSC10_RS03380	COG0351	phosphomethylpyrimidine kinase
FSC10_RS03380	COG0352	thiamine-phosphate diphosphorylase activity
FSC10_RS03380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC10_RS03415	COG4772	TonB-dependent receptor
FSC10_RS03420	COG0431	NADPH-dependent FMN reductase
FSC10_RS03425	COG0798	PFAM Bile acid sodium symporter
FSC10_RS03430	COG0640	Transcriptional regulator
FSC10_RS03450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC10_RS03455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FSC10_RS03455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC10_RS03460	COG0745	RESPONSE REGULATOR receiver
FSC10_RS03465	COG2205	protein histidine kinase activity
FSC10_RS03475	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC10_RS03495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSC10_RS03510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC10_RS03520	COG0713	ATP synthesis coupled electron transport
FSC10_RS03525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC10_RS03545	COG1278	Cold shock
FSC10_RS03555	COG0583	DNA-binding transcription factor activity
FSC10_RS03570	COG0531	amino acid
FSC10_RS03575	COG4303	Ethanolamine ammonia lyase large subunit
FSC10_RS03580	COG4302	ethanolamine ammonia-lyase activity
FSC10_RS03590	COG0668	transmembrane transport
FSC10_RS03595	COG2081	HI0933 family
FSC10_RS03605	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FSC10_RS03620	COG0004	ammonium transporteR
FSC10_RS03625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FSC10_RS03640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC10_RS03640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC10_RS03655	COG0489	protein tyrosine kinase activity
FSC10_RS03690	COG0442	prolyl-tRNA aminoacylation
FSC10_RS03700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC10_RS03725	COG0840	transmembrane signaling receptor activity
FSC10_RS03815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSC10_RS03825	COG1289	transmembrane transporter activity
FSC10_RS03830	COG2814	Major facilitator Superfamily
FSC10_RS03840	COG0786	glutamate:sodium symporter activity
FSC10_RS03845	COG1115	amino acid carrier protein
FSC10_RS03855	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC10_RS03860	COG1607	acyl-coa hydrolase
FSC10_RS03870	COG2814	Major facilitator Superfamily
FSC10_RS03875	COG0583	DNA-binding transcription factor activity
FSC10_RS03895	COG0523	cobalamin synthesis protein
FSC10_RS03905	COG1285	pathogenesis
FSC10_RS03915	COG4251	negative regulation of phosphorylation
FSC10_RS03915	COG5001	Diguanylate cyclase
FSC10_RS03915	COG2203	Gaf domain
FSC10_RS03915	COG3706	GGDEF domain
FSC10_RS03945	COG0242	peptide deformylase activity
FSC10_RS03950	COG0393	Putative heavy-metal-binding
FSC10_RS03955	COG0393	Putative heavy-metal-binding
FSC10_RS03960	COG1538	Outer membrane efflux protein
FSC10_RS03970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC10_RS03985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSC10_RS03995	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FSC10_RS04005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSC10_RS04010	COG1648	precorrin-2 dehydrogenase activity
FSC10_RS04010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSC10_RS04015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FSC10_RS04025	COG0531	amino acid
FSC10_RS04040	COG0321	lipoyl(octanoyl) transferase activity
FSC10_RS04045	COG2921	Belongs to the UPF0250 family
FSC10_RS04050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSC10_RS04075	COG0586	Pfam SNARE associated Golgi protein
FSC10_RS04100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSC10_RS04130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSC10_RS04160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FSC10_RS04175	COG0358	DNA primase activity
FSC10_RS04185	COG0564	pseudouridine synthase activity
FSC10_RS04210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC10_RS04235	COG0251	oxidation-reduction process
FSC10_RS04240	COG1309	transcriptional regulator
FSC10_RS04250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSC10_RS04255	COG0505	Belongs to the CarA family
FSC10_RS04280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FSC10_RS04285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC10_RS04295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSC10_RS04330	COG1253	flavin adenine dinucleotide binding
FSC10_RS04350	COG2239	Acts as a magnesium transporter
FSC10_RS04360	COG0501	Belongs to the peptidase M48B family
FSC10_RS04365	COG0739	heme binding
FSC10_RS04365	COG0741	lytic transglycosylase activity
FSC10_RS04365	COG1196	nuclear chromosome segregation
FSC10_RS04370	COG0037	tRNA processing
FSC10_RS04380	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FSC10_RS04385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC10_RS04400	COG0583	DNA-binding transcription factor activity
FSC10_RS04405	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS04410	COG2814	Major facilitator Superfamily
FSC10_RS04415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSC10_RS04425	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FSC10_RS04450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC10_RS04455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSC10_RS04460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSC10_RS04470	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FSC10_RS04505	COG1115	amino acid carrier protein
FSC10_RS04510	COG1113	amino acid transport
FSC10_RS04530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSC10_RS04545	COG1280	lysine exporter protein (LysE YggA)
FSC10_RS04590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC10_RS04610	COG1671	Belongs to the UPF0178 family
FSC10_RS04625	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC10_RS04630	COG1136	(ABC) transporter
FSC10_RS04635	COG2333	competence protein COMEC
FSC10_RS04635	COG0658	competence protein
FSC10_RS04655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSC10_RS04660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSC10_RS04665	COG0628	permease
FSC10_RS04670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC10_RS04700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC10_RS04715	COG2885	chlorophyll binding
FSC10_RS04720	COG0823	Involved in the tonB-independent uptake of proteins
FSC10_RS04740	COG0824	Thioesterase
FSC10_RS04750	COG1473	amidohydrolase
FSC10_RS04770	COG2255	four-way junction helicase activity
FSC10_RS04785	COG0047	phosphoribosylformylglycinamidine synthase activity
FSC10_RS04785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSC10_RS04800	COG0583	DNA-binding transcription factor activity
FSC10_RS04810	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FSC10_RS04815	COG0778	Nitroreductase
FSC10_RS04820	COG1024	Enoyl-CoA hydratase
FSC10_RS04825	COG1051	belongs to the nudix hydrolase family
FSC10_RS04825	COG1056	cytidyltransferase-related domain
FSC10_RS04830	COG2353	YceI-like domain
FSC10_RS04840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSC10_RS04850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSC10_RS04855	COG0602	queuosine metabolic process
FSC10_RS04870	COG0583	DNA-binding transcription factor activity
FSC10_RS04875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSC10_RS04880	COG4208	sulfate ABC transporter
FSC10_RS04895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC10_RS04900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC10_RS04910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSC10_RS04930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC10_RS04955	COG0571	ribonuclease III activity
FSC10_RS04960	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSC10_RS04970	COG1381	Involved in DNA repair and RecF pathway recombination
FSC10_RS04975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSC10_RS05005	COG0436	Aminotransferase
FSC10_RS05010	COG0024	Methionine aminopeptidase
FSC10_RS05015	COG0052	Belongs to the universal ribosomal protein uS2 family
FSC10_RS05040	COG2951	lytic endotransglycosylase activity
FSC10_RS05055	COG0842	Transport permease protein
FSC10_RS05060	COG1131	(ABC) transporter
FSC10_RS05140	COG1414	Transcriptional regulator
FSC10_RS05145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC10_RS05150	COG1414	Transcriptional regulator
FSC10_RS05155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC10_RS05160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC10_RS05165	COG0183	Belongs to the thiolase family
FSC10_RS05170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSC10_RS05175	COG0596	Alpha beta hydrolase
FSC10_RS05180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSC10_RS05185	COG3485	protocatechuate 3,4-dioxygenase
FSC10_RS05190	COG3485	protocatechuate 3,4-dioxygenase
FSC10_RS05210	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS05220	COG1012	belongs to the aldehyde dehydrogenase family
FSC10_RS05225	COG1024	Enoyl-CoA hydratase
FSC10_RS05230	COG2814	Major facilitator Superfamily
FSC10_RS05245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC10_RS05255	COG0583	DNA-binding transcription factor activity
FSC10_RS05260	COG1053	succinate dehydrogenase
FSC10_RS05310	COG1278	Cold shock
FSC10_RS05325	COG1380	Effector of murein hydrolase LrgA
FSC10_RS05330	COG0583	DNA-binding transcription factor activity
FSC10_RS05335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSC10_RS05380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC10_RS05400	COG3634	alkyl hydroperoxide reductase activity
FSC10_RS05405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC10_RS05415	COG0789	Transcriptional regulator
FSC10_RS05430	COG1720	tRNA m6t6A37 methyltransferase activity
FSC10_RS05440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSC10_RS05450	COG0745	RESPONSE REGULATOR receiver
FSC10_RS05455	COG0642	Histidine kinase
FSC10_RS05465	COG0352	thiamine-phosphate diphosphorylase activity
FSC10_RS05475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC10_RS05480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSC10_RS05485	COG3139	Protein of unknown function (DUF1315)
FSC10_RS05495	COG1301	dicarboxylic acid transport
FSC10_RS05500	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS05505	COG0693	protein deglycase activity
FSC10_RS05515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSC10_RS05520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSC10_RS05545	COG2252	PERMEase
FSC10_RS05550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSC10_RS05565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSC10_RS05575	COG0527	aspartate kinase activity
FSC10_RS05585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSC10_RS05600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSC10_RS05615	COG1047	Peptidyl-prolyl cis-trans
FSC10_RS05620	COG1252	NADH dehydrogenase
FSC10_RS05640	COG2351	hydroxyisourate hydrolase activity
FSC10_RS05660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC10_RS05660	COG2755	lipolytic protein G-D-S-L family
FSC10_RS05665	COG0436	Aminotransferase
FSC10_RS05670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSC10_RS05675	COG0386	Belongs to the glutathione peroxidase family
FSC10_RS05690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSC10_RS05710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FSC10_RS05730	COG0012	GTP binding
FSC10_RS05735	COG2011	ABC-type metal ion transport system permease component
FSC10_RS05740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC10_RS05745	COG1464	Belongs to the NlpA lipoprotein family
FSC10_RS05750	COG1464	Belongs to the NlpA lipoprotein family
FSC10_RS05810	COG1454	alcohol dehydrogenase
FSC10_RS05840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSC10_RS05840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSC10_RS05845	COG1254	Belongs to the acylphosphatase family
FSC10_RS05875	COG3634	alkyl hydroperoxide reductase activity
FSC10_RS05905	COG1643	Atp-dependent helicase
FSC10_RS05925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC10_RS05930	COG2707	UPF0756 membrane protein
FSC10_RS05950	COG0564	pseudouridine synthase activity
FSC10_RS05955	COG0802	atpase or kinase
FSC10_RS05960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSC10_RS05970	COG1923	regulation of RNA biosynthetic process
FSC10_RS05975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC10_RS05985	COG3178	'Phosphotransferase
FSC10_RS05990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSC10_RS06000	COG1192	Involved in chromosome partitioning
FSC10_RS06005	COG1475	DNA binding
FSC10_RS06010	COG0811	peptide transport
FSC10_RS06020	COG1132	(ABC) transporter
FSC10_RS06025	COG1663	tetraacyldisaccharide 4'-kinase activity
FSC10_RS06045	COG0084	hydrolase, TatD family'
FSC10_RS06080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSC10_RS06110	COG0776	regulation of translation
FSC10_RS06130	COG2431	L-lysine efflux transmembrane transporter activity
FSC10_RS06145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSC10_RS06170	COG1253	flavin adenine dinucleotide binding
FSC10_RS06200	COG0308	aminopeptidase N
FSC10_RS06210	COG0589	response to stress
FSC10_RS06215	COG0589	response to stress
FSC10_RS06225	COG3135	benzoate transporter
FSC10_RS06235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSC10_RS06250	COG0183	Belongs to the thiolase family
FSC10_RS06275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSC10_RS06280	COG0824	Thioesterase
FSC10_RS06285	COG1454	alcohol dehydrogenase
FSC10_RS06290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSC10_RS06295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FSC10_RS06310	COG0069	glutamate synthase activity
FSC10_RS06320	COG2308	Evidence 4 Homologs of previously reported genes of
FSC10_RS06330	COG1305	Transglutaminase-like
FSC10_RS06345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSC10_RS06365	COG0360	Binds together with S18 to 16S ribosomal RNA
FSC10_RS06375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FSC10_RS06380	COG1845	cytochrome c oxidase, subunit III
FSC10_RS06385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSC10_RS06390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSC10_RS06415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC10_RS06430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSC10_RS06435	COG2890	protein-(glutamine-N5) methyltransferase activity
FSC10_RS06440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC10_RS06445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC10_RS06485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSC10_RS06510	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FSC10_RS06515	COG0477	Major facilitator Superfamily
FSC10_RS06520	COG0729	surface antigen
FSC10_RS06535	COG1570	exodeoxyribonuclease VII activity
FSC10_RS06570	COG0786	glutamate:sodium symporter activity
FSC10_RS06575	COG3300	MHYT domain
FSC10_RS06575	COG5001	Diguanylate cyclase
FSC10_RS06600	COG0024	Methionine aminopeptidase
FSC10_RS06605	COG0583	DNA-binding transcription factor activity
FSC10_RS06610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSC10_RS06625	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC10_RS06625	COG1902	pentaerythritol trinitrate reductase activity
FSC10_RS06655	COG0148	phosphopyruvate hydratase activity
FSC10_RS06660	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FSC10_RS06670	COG0772	Belongs to the SEDS family
FSC10_RS06690	COG4890	Cyd operon protein YbgT
FSC10_RS06695	COG1294	oxidase, subunit
FSC10_RS06745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSC10_RS06765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC10_RS06775	COG0133	tryptophan synthase activity
FSC10_RS06780	COG0517	IMP dehydrogenase activity
FSC10_RS06810	COG0612	Peptidase, M16
FSC10_RS06815	COG0552	protein localization to endoplasmic reticulum
FSC10_RS06890	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS06895	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS06950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC10_RS06955	COG0730	response to heat
FSC10_RS06960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC10_RS06965	COG2207	Transcriptional regulator
FSC10_RS06970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC10_RS06975	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS06980	COG2169	Transcriptional regulator
FSC10_RS07000	COG1525	nuclease
FSC10_RS07065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC10_RS07070	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSC10_RS07080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC10_RS07095	COG2814	Major facilitator Superfamily
FSC10_RS07100	COG0509	glycine decarboxylation via glycine cleavage system
FSC10_RS07115	COG1132	(ABC) transporter
FSC10_RS07120	COG0668	transmembrane transport
FSC10_RS07135	COG3122	Protein conserved in bacteria
FSC10_RS07140	COG3619	membrane
FSC10_RS07155	COG0640	Transcriptional regulator
FSC10_RS07160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC10_RS07170	COG0789	Transcriptional regulator
FSC10_RS07195	COG0830	nickel cation binding
FSC10_RS07210	COG0831	urea catabolic process
FSC10_RS07220	COG0804	urea catabolic process
FSC10_RS07235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC10_RS07240	COG0183	Belongs to the thiolase family
FSC10_RS07245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC10_RS07250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC10_RS07255	COG3135	benzoate transporter
FSC10_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS07265	COG0633	Ferredoxin
FSC10_RS07265	COG0543	2 iron, 2 sulfur cluster binding
FSC10_RS07270	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FSC10_RS07275	COG4638	Rieske (2fe-2S)
FSC10_RS07285	COG4829	muconolactone delta-isomerase
FSC10_RS07290	COG4948	Mandelate Racemase Muconate Lactonizing
FSC10_RS07295	COG0583	DNA-binding transcription factor activity
FSC10_RS07300	COG2814	Major facilitator Superfamily
FSC10_RS07310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSC10_RS07315	COG0318	PFAM AMP-dependent synthetase and ligase
FSC10_RS07320	COG1017	nitric oxide dioxygenase activity
FSC10_RS07320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC10_RS07335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC10_RS07340	COG0583	DNA-binding transcription factor activity
FSC10_RS07355	COG0439	Biotin carboxylase
FSC10_RS07365	COG0864	Transcriptional regulator
FSC10_RS07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSC10_RS07400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC10_RS07410	COG1116	anion transmembrane transporter activity
FSC10_RS07410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC10_RS07420	COG2223	nitrite transmembrane transporter activity
FSC10_RS07425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC10_RS07430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC10_RS07435	COG0243	molybdopterin cofactor binding
FSC10_RS07445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSC10_RS07455	COG0314	molybdopterin synthase activity
FSC10_RS07460	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSC10_RS07460	COG0315	cyclic pyranopterin monophosphate synthase activity
FSC10_RS07465	COG0303	'Molybdopterin
FSC10_RS07470	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSC10_RS07475	COG4149	molybdate abc transporter
FSC10_RS07480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FSC10_RS07485	COG2223	nitrite transmembrane transporter activity
FSC10_RS07495	COG0347	Belongs to the P(II) protein family
FSC10_RS07515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC10_RS07520	COG1309	transcriptional regulator
FSC10_RS07540	COG1944	ATP diphosphatase activity
FSC10_RS07555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC10_RS07570	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FSC10_RS07575	COG1877	trehalose-phosphatase activity
FSC10_RS07585	COG0583	DNA-binding transcription factor activity
FSC10_RS07595	COG0583	DNA-binding transcription factor activity
FSC10_RS07650	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FSC10_RS07655	COG2116	formate transmembrane transporter activity
FSC10_RS07695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSC10_RS07700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC10_RS07715	COG2194	sulfuric ester hydrolase activity
FSC10_RS07720	COG0745	RESPONSE REGULATOR receiver
FSC10_RS07725	COG0642	Histidine kinase
FSC10_RS07755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSC10_RS07775	COG3550	peptidyl-serine autophosphorylation
FSC10_RS07780	COG2188	Transcriptional regulator
FSC10_RS07785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FSC10_RS07795	COG4521	taurine ABC transporter
FSC10_RS07800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC10_RS07905	COG0596	Alpha beta hydrolase
FSC10_RS07935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC10_RS07940	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FSC10_RS07965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FSC10_RS07980	COG0439	Biotin carboxylase
FSC10_RS07990	COG3706	GGDEF domain
FSC10_RS08000	COG2814	Major facilitator Superfamily
FSC10_RS08035	COG1058	Belongs to the CinA family
FSC10_RS08035	COG1546	Belongs to the CinA family
FSC10_RS08045	COG0372	Belongs to the citrate synthase family
FSC10_RS08065	COG0477	Major facilitator Superfamily
FSC10_RS08080	COG0542	response to heat
FSC10_RS08085	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSC10_RS08110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC10_RS08120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSC10_RS08125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSC10_RS08130	COG0569	domain protein
FSC10_RS08135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSC10_RS08155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSC10_RS08165	COG1585	Membrane protein implicated in regulation of membrane protease activity
FSC10_RS08185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC10_RS08190	COG0776	regulation of translation
FSC10_RS08215	COG0822	iron-sulfur transferase activity
FSC10_RS08220	COG0316	Belongs to the HesB IscA family
FSC10_RS08250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSC10_RS08260	COG1027	Aspartate ammonia-lyase
FSC10_RS08265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC10_RS08275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC10_RS08275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC10_RS08275	COG0506	proline dehydrogenase activity
FSC10_RS08295	COG3781	membrane
FSC10_RS08300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC10_RS08330	COG0697	spore germination
FSC10_RS08355	COG0424	maF-like protein
FSC10_RS08365	COG2850	peptidyl-arginine hydroxylation
FSC10_RS08370	COG0625	glutathione transferase activity
FSC10_RS08375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC10_RS08380	COG0702	epimerase
FSC10_RS08385	COG0268	Binds directly to 16S ribosomal RNA
FSC10_RS08400	COG1011	Hydrolase
FSC10_RS08405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSC10_RS08415	COG2137	regulation of response to DNA damage stimulus
FSC10_RS08430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC10_RS08435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSC10_RS08440	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC10_RS08450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC10_RS08465	COG0575	Belongs to the CDS family
FSC10_RS08470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSC10_RS08490	COG3852	Histidine kinase
FSC10_RS08505	COG2814	Major facilitator Superfamily
FSC10_RS08510	COG0445	tRNA wobble uridine modification
FSC10_RS08540	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FSC10_RS08545	COG0138	bifunctional purine biosynthesis protein purh
FSC10_RS08570	COG1464	Belongs to the NlpA lipoprotein family
FSC10_RS08575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC10_RS08580	COG2011	ABC-type metal ion transport system permease component
FSC10_RS08610	COG5001	Diguanylate cyclase
FSC10_RS08610	COG4251	negative regulation of phosphorylation
FSC10_RS08610	COG2203	Gaf domain
FSC10_RS08610	COG3706	GGDEF domain
FSC10_RS08620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSC10_RS08630	COG4122	O-methyltransferase activity
FSC10_RS08635	COG0589	response to stress
FSC10_RS08665	COG1137	ATPase activity
FSC10_RS08670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FSC10_RS08680	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FSC10_RS08685	COG0517	IMP dehydrogenase activity
FSC10_RS08685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSC10_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS08730	COG0519	Catalyzes the synthesis of GMP from XMP
FSC10_RS08730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC10_RS08740	COG2353	YceI-like domain
FSC10_RS08745	COG0456	acetyltransferase
FSC10_RS08755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSC10_RS08760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSC10_RS08770	COG2391	methyltransferase activity
FSC10_RS08840	COG3179	chitinase
FSC10_RS08965	COG5410	chromosome segregation
FSC10_RS09115	COG1309	transcriptional regulator
FSC10_RS09175	COG0352	thiamine-phosphate diphosphorylase activity
FSC10_RS09190	COG3025	triphosphatase activity
FSC10_RS09210	COG3618	amidohydrolase
FSC10_RS09215	COG0612	Peptidase, M16
FSC10_RS09225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC10_RS09235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC10_RS09285	COG0515	serine threonine protein kinase
FSC10_RS09285	COG2815	serine threonine protein kinase
FSC10_RS09340	COG4783	chaperone-mediated protein folding
FSC10_RS09395	COG0778	Nitroreductase
FSC10_RS09405	COG0513	Belongs to the DEAD box helicase family
FSC10_RS09410	COG1278	Cold shock
FSC10_RS09425	COG2363	Small membrane protein
FSC10_RS09450	COG0659	secondary active sulfate transmembrane transporter activity
FSC10_RS09455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSC10_RS09475	COG3047	cAMP biosynthetic process
FSC10_RS09475	COG2885	chlorophyll binding
FSC10_RS09485	COG0540	Belongs to the ATCase OTCase family
FSC10_RS09505	COG0667	Aldo Keto reductase
FSC10_RS09515	COG1765	OsmC-like protein
FSC10_RS09520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC10_RS09540	COG1136	(ABC) transporter
FSC10_RS09550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC10_RS09555	COG0281	malic enzyme
FSC10_RS09580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FSC10_RS09605	COG1401	restriction endodeoxyribonuclease activity
FSC10_RS09605	COG1401	restriction endodeoxyribonuclease activity
FSC10_RS09645	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FSC10_RS09650	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FSC10_RS09700	COG3620	sequence-specific DNA binding
FSC10_RS09735	COG0582	viral genome integration into host DNA
FSC10_RS09755	COG0714	Associated with various cellular activities
FSC10_RS09760	COG2879	small protein
FSC10_RS09765	COG1966	Carbon starvation protein
FSC10_RS09770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSC10_RS09810	COG1067	ATP-dependent peptidase activity
FSC10_RS09815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FSC10_RS09820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSC10_RS09825	COG0583	DNA-binding transcription factor activity
FSC10_RS09850	COG1686	Belongs to the peptidase S11 family
FSC10_RS09855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSC10_RS09870	COG2351	hydroxyisourate hydrolase activity
FSC10_RS09885	COG5002	protein histidine kinase activity
FSC10_RS09925	COG0616	signal peptide processing
FSC10_RS09935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSC10_RS09945	COG0573	inorganic phosphate transmembrane transporter activity
FSC10_RS09955	COG0076	glutamate decarboxylase activity
FSC10_RS09960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSC10_RS09970	COG0671	phosphoesterase, PA-phosphatase related
FSC10_RS09975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSC10_RS09985	COG2814	Major facilitator Superfamily
FSC10_RS09990	COG1733	regulation of RNA biosynthetic process
FSC10_RS10015	COG0556	nucleotide-excision repair
FSC10_RS10050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC10_RS10055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC10_RS10060	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS10070	COG2084	Dehydrogenase
FSC10_RS10075	COG2233	PERMEase
FSC10_RS10080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC10_RS10085	COG0251	oxidation-reduction process
FSC10_RS10090	COG1335	isochorismatase
FSC10_RS10095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC10_RS10100	COG0596	Alpha beta hydrolase
FSC10_RS10110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC10_RS10120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSC10_RS10165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FSC10_RS10180	COG0174	glutamine synthetase
FSC10_RS10185	COG0512	Glutamine amidotransferase of anthranilate synthase
FSC10_RS10190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSC10_RS10205	COG0302	gtp cyclohydrolase
FSC10_RS10220	COG3706	GGDEF domain
FSC10_RS10235	COG3739	integral membrane protein
FSC10_RS10250	COG1741	Belongs to the pirin family
FSC10_RS10265	COG2197	response regulator
FSC10_RS10270	COG4585	Histidine kinase
FSC10_RS10290	COG0640	Transcriptional regulator
FSC10_RS10305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSC10_RS10315	COG0745	RESPONSE REGULATOR receiver
FSC10_RS10320	COG0642	Histidine kinase
FSC10_RS10330	COG1902	pentaerythritol trinitrate reductase activity
FSC10_RS10330	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC10_RS10340	COG0277	FAD linked oxidase domain protein
FSC10_RS10350	COG2186	Transcriptional regulator
FSC10_RS10355	COG1620	l-lactate permease
FSC10_RS10370	COG4251	negative regulation of phosphorylation
FSC10_RS10370	COG2203	Gaf domain
FSC10_RS10370	COG3706	GGDEF domain
FSC10_RS10370	COG5001	Diguanylate cyclase
FSC10_RS10375	COG0418	dihydroorotase activity
FSC10_RS10380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSC10_RS10390	COG0833	amino acid
FSC10_RS10400	COG0833	amino acid
FSC10_RS10440	COG4172	Belongs to the ABC transporter superfamily
FSC10_RS10445	COG4239	(ABC) transporter, permease
FSC10_RS10450	COG4174	ABC transporter (Permease)
FSC10_RS10455	COG4166	transmembrane transport
FSC10_RS10460	COG0741	lytic transglycosylase activity
FSC10_RS10460	COG1388	LysM domain
FSC10_RS10510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC10_RS10515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC10_RS10540	COG2155	Conserved Protein
FSC10_RS10550	COG0006	proline dipeptidase activity
FSC10_RS10585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSC10_RS10595	COG2234	aminopeptidase activity
FSC10_RS10605	COG3384	dioxygenase
FSC10_RS10615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSC10_RS10620	COG2878	Part of a membrane complex involved in electron transport
FSC10_RS10625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSC10_RS10650	COG0768	penicillin binding
FSC10_RS10655	COG0742	ribosomal rna small subunit methyltransferase
FSC10_RS10725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSC10_RS10745	COG4221	oxidoreductase activity
FSC10_RS10745	COG0604	alcohol dehydrogenase
FSC10_RS10745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC10_RS10745	COG3321	synthase
FSC10_RS10790	COG2268	Band 7 protein
FSC10_RS10795	COG1649	PFAM Uncharacterised BCR, COG1649
FSC10_RS10795	COG0726	polysaccharide deacetylase
FSC10_RS10805	COG1215	transferase activity, transferring glycosyl groups
FSC10_RS10810	COG1649	PFAM Uncharacterised BCR, COG1649
FSC10_RS10810	COG0726	polysaccharide deacetylase
FSC10_RS10820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSC10_RS10830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC10_RS10845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSC10_RS10850	COG1053	succinate dehydrogenase
FSC10_RS10855	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FSC10_RS10875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC10_RS10875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSC10_RS10910	COG2321	neutral zinc metallopeptidase
FSC10_RS10915	COG2354	Protein conserved in bacteria
FSC10_RS10935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSC10_RS10940	COG1773	rubredoxin
FSC10_RS10945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC10_RS10955	COG0583	DNA-binding transcription factor activity
FSC10_RS10965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC10_RS10975	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FSC10_RS10980	COG4181	ATPase activity
FSC10_RS11005	COG4771	TonB-dependent receptor
FSC10_RS11025	COG0306	phosphate transporter
FSC10_RS11050	COG2376	Dihydroxyacetone kinase
FSC10_RS11055	COG2066	Belongs to the glutaminase family
FSC10_RS11060	COG0300	oxidoreductase activity
FSC10_RS11070	COG0525	valine-tRNA ligase activity
FSC10_RS11090	COG2828	Protein conserved in bacteria
FSC10_RS11095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC10_RS11100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FSC10_RS11105	COG0583	DNA-binding transcription factor activity
FSC10_RS11115	COG3384	dioxygenase
FSC10_RS11150	COG2323	membrane
FSC10_RS11175	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC10_RS11190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC10_RS11195	COG0142	geranyltranstransferase activity
FSC10_RS11200	COG2828	Protein conserved in bacteria
FSC10_RS11205	COG1113	amino acid transport
FSC10_RS11235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC10_RS11240	COG1530	ribonuclease E activity
FSC10_RS11245	COG0424	maF-like protein
FSC10_RS11250	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FSC10_RS11255	COG1792	Involved in formation and maintenance of cell shape
FSC10_RS11260	COG1077	Cell shape determining protein MreB Mrl
FSC10_RS11265	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC10_RS11275	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC10_RS11295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FSC10_RS11310	COG1294	oxidase, subunit
FSC10_RS11315	COG1271	oxidase subunit
FSC10_RS11335	COG4106	trans-aconitate 2-methyltransferase activity
FSC10_RS11350	COG0596	Alpha beta hydrolase
FSC10_RS11355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FSC10_RS11375	COG1113	amino acid transport
FSC10_RS11380	COG1448	Aminotransferase
FSC10_RS11400	COG0625	glutathione transferase activity
FSC10_RS11415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC10_RS11430	COG3177	Filamentation induced by cAMP protein fic
FSC10_RS11490	COG1785	Belongs to the alkaline phosphatase family
FSC10_RS11495	COG1785	Belongs to the alkaline phosphatase family
FSC10_RS11505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FSC10_RS11595	COG0582	viral genome integration into host DNA
FSC10_RS11605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSC10_RS11610	COG2050	protein possibly involved in aromatic compounds catabolism
FSC10_RS11635	COG0420	3'-5' exonuclease activity
FSC10_RS11665	COG0735	belongs to the Fur family
FSC10_RS11670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC10_RS11675	COG2914	Belongs to the UPF0125 (RnfH) family
FSC10_RS11690	COG0121	glutamine amidotransferase
FSC10_RS11700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC10_RS11705	COG0756	dUTP diphosphatase activity
FSC10_RS11715	COG2885	chlorophyll binding
FSC10_RS11720	COG0204	Acyl-transferase
FSC10_RS11750	COG1674	ftsk spoiiie
FSC10_RS11750	COG0531	amino acid
FSC10_RS11755	COG0492	ferredoxin-NADP+ reductase activity
FSC10_RS11760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSC10_RS11770	COG0456	acetyltransferase
FSC10_RS11780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSC10_RS11785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSC10_RS11795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSC10_RS11815	COG1113	amino acid transport
FSC10_RS11820	COG0251	oxidation-reduction process
FSC10_RS11840	COG1652	LysM domain
FSC10_RS11845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSC10_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS11865	COG1399	metal-binding, possibly nucleic acid-binding protein
FSC10_RS11870	COG3101	peptidyl-lysine hydroxylation
FSC10_RS11875	COG0009	L-threonylcarbamoyladenylate synthase
FSC10_RS11895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSC10_RS11900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSC10_RS11915	COG2193	ferroxidase activity
FSC10_RS11920	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FSC10_RS11925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSC10_RS11935	COG1196	nuclear chromosome segregation
FSC10_RS11945	COG0730	response to heat
FSC10_RS11950	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FSC10_RS11950	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FSC10_RS11960	COG3545	Serine hydrolase
FSC10_RS11965	COG3545	Serine hydrolase
FSC10_RS11970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSC10_RS12015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSC10_RS12025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSC10_RS12040	COG4269	membrane
FSC10_RS12060	COG1968	undecaprenyl-diphosphatase activity
FSC10_RS12065	COG1214	PFAM Peptidase M22, glycoprotease
FSC10_RS12075	COG0494	nUDIX hydrolase
FSC10_RS12090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSC10_RS12115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC10_RS12120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC10_RS12130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSC10_RS12135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSC10_RS12140	COG0625	glutathione transferase activity
FSC10_RS12145	COG2969	positive regulation of protein catabolic process
FSC10_RS12195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC10_RS12200	COG1764	response to oxidative stress
FSC10_RS12245	COG0037	tRNA processing
FSC10_RS12280	COG0072	phenylalanine-tRNA ligase activity
FSC10_RS12285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSC10_RS12315	COG1238	metal cluster binding
FSC10_RS12325	COG0625	glutathione transferase activity
FSC10_RS12335	COG0546	phosphoglycolate phosphatase activity
FSC10_RS12360	COG0318	PFAM AMP-dependent synthetase and ligase
FSC10_RS12380	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSC10_RS12465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSC10_RS12480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSC10_RS12485	COG1660	Displays ATPase and GTPase activities
FSC10_RS12500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSC10_RS12505	COG0617	tRNA 3'-terminal CCA addition
FSC10_RS12510	COG1555	photosystem II stabilization
FSC10_RS12515	COG3956	TIGRFAM MazG family protein
FSC10_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS12535	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC10_RS12545	COG0124	histidyl-tRNA synthetase
FSC10_RS12555	COG1426	Protein conserved in bacteria
FSC10_RS12575	COG2975	iron-sulfur cluster assembly
FSC10_RS12610	COG0440	acetolactate synthase activity
FSC10_RS12615	COG0028	Belongs to the TPP enzyme family
FSC10_RS12640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC10_RS12645	COG1136	(ABC) transporter
FSC10_RS12645	COG0577	efflux transmembrane transporter activity
FSC10_RS12650	COG1538	Outer membrane efflux protein
FSC10_RS12660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FSC10_RS12670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSC10_RS12675	COG1162	GTPase activity
FSC10_RS12705	COG0084	hydrolase, TatD family'
FSC10_RS12720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSC10_RS12735	COG0793	Belongs to the peptidase S41A family
FSC10_RS12760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSC10_RS12765	COG0280	phosphate acetyltransferase
FSC10_RS12765	COG0857	belongs to the CobB CobQ family
FSC10_RS12775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC10_RS12775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC10_RS12790	COG0740	serine-type endopeptidase activity
FSC10_RS12800	COG4771	TonB-dependent receptor
FSC10_RS12805	COG4774	siderophore transport
FSC10_RS12810	COG4774	siderophore transport
FSC10_RS12815	COG3128	pkhd-type hydroxylase
FSC10_RS12825	COG4774	siderophore transport
FSC10_RS12830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSC10_RS12835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC10_RS12840	COG2813	Specifically methylates the guanine in position
FSC10_RS12840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC10_RS12890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FSC10_RS12895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSC10_RS12935	COG0788	formyltetrahydrofolate deformylase activity
FSC10_RS12960	COG4651	solute:proton antiporter activity
FSC10_RS12960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSC10_RS12975	COG0724	RNA recognition motif
FSC10_RS12980	COG0210	DNA helicase
FSC10_RS12985	COG1929	Belongs to the glycerate kinase type-1 family
FSC10_RS13015	COG2900	Belongs to the SlyX family
FSC10_RS13025	COG1560	Kdo2-lipid A biosynthetic process
FSC10_RS13055	COG0252	asparaginase activity
FSC10_RS13085	COG0473	3-isopropylmalate dehydrogenase activity
FSC10_RS13100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSC10_RS13150	COG1960	acyl-CoA dehydrogenase activity
FSC10_RS13155	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FSC10_RS13165	COG0519	Catalyzes the synthesis of GMP from XMP
FSC10_RS13175	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC10_RS13180	COG3384	dioxygenase
FSC10_RS13185	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS13200	COG4638	Rieske (2fe-2S)
FSC10_RS13205	COG0583	DNA-binding transcription factor activity
FSC10_RS13225	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSC10_RS13230	COG3971	2-oxopent-4-enoate hydratase activity
FSC10_RS13235	COG0546	phosphoglycolate phosphatase activity
FSC10_RS13250	COG1530	ribonuclease E activity
FSC10_RS13255	COG0318	PFAM AMP-dependent synthetase and ligase
FSC10_RS13280	COG1983	PspC domain protein
FSC10_RS13290	COG0471	metal ion transport
FSC10_RS13310	COG0751	glycine-tRNA ligase activity
FSC10_RS13340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC10_RS13370	COG0493	'glutamate synthase
FSC10_RS13380	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FSC10_RS13395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC10_RS13410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSC10_RS13420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSC10_RS13420	COG0644	oxidoreductase
FSC10_RS13455	COG3501	Rhs element vgr protein
FSC10_RS13465	COG4535	Mg2 and Co2 transporter CorC
FSC10_RS13470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSC10_RS13490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSC10_RS13500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSC10_RS13515	COG0789	Transcriptional regulator
FSC10_RS13520	COG2841	Protein conserved in bacteria
FSC10_RS13525	COG1185	polyribonucleotide nucleotidyltransferase activity
FSC10_RS13530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSC10_RS13545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC10_RS13550	COG1074	ATP-dependent DNA helicase activity
FSC10_RS13555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSC10_RS13590	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC10_RS13630	COG0745	RESPONSE REGULATOR receiver
FSC10_RS13635	COG2205	protein histidine kinase activity
FSC10_RS13640	COG0427	acetyl-CoA hydrolase
FSC10_RS13650	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSC10_RS13680	COG0326	Molecular chaperone. Has ATPase activity
FSC10_RS13695	COG2056	Na+-H+ antiporter family
FSC10_RS13725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSC10_RS13730	COG0085	RNA polymerase activity
FSC10_RS13745	COG0081	regulation of translation
FSC10_RS13750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSC10_RS13770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSC10_RS13800	COG0546	phosphoglycolate phosphatase activity
FSC10_RS13830	COG0824	Thioesterase
FSC10_RS13850	COG0181	hydroxymethylbilane synthase activity
FSC10_RS13860	COG3275	phosphorelay sensor kinase activity
FSC10_RS13875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSC10_RS13885	COG0322	excinuclease ABC activity
FSC10_RS13900	COG3706	GGDEF domain
FSC10_RS13905	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC10_RS13905	COG1024	Enoyl-CoA hydratase
FSC10_RS13965	COG0131	Imidazoleglycerol-phosphate dehydratase
FSC10_RS13970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSC10_RS14015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FSC10_RS14020	COG0107	imidazoleglycerol-phosphate synthase activity
FSC10_RS14050	COG3158	transport of potassium into the cell
FSC10_RS14080	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FSC10_RS14110	COG2814	Major facilitator Superfamily
FSC10_RS14120	COG0352	thiamine-phosphate diphosphorylase activity
FSC10_RS14120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC10_RS14120	COG0351	phosphomethylpyrimidine kinase
FSC10_RS14125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSC10_RS14130	COG3706	GGDEF domain
FSC10_RS14145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC10_RS14155	COG3162	membrane
FSC10_RS14160	COG2205	protein histidine kinase activity
FSC10_RS14160	COG0784	Response regulator, receiver
FSC10_RS14175	COG0431	NADPH-dependent FMN reductase
FSC10_RS14185	COG0307	riboflavin synthase, alpha
FSC10_RS14200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC10_RS14210	COG0668	transmembrane transport
FSC10_RS14215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC10_RS14220	COG1519	Transferase
FSC10_RS14225	COG1902	pentaerythritol trinitrate reductase activity
FSC10_RS14230	COG0640	Transcriptional regulator
FSC10_RS14250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSC10_RS14260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC10_RS14275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC10_RS14275	COG0426	domain, Protein
FSC10_RS14280	COG2119	membrane
FSC10_RS14310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSC10_RS14320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FSC10_RS14345	COG0189	ligase activity
FSC10_RS14360	COG2132	Multicopper oxidase
FSC10_RS14370	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS14385	COG0708	Exodeoxyribonuclease III
FSC10_RS14390	COG1393	Belongs to the ArsC family
FSC10_RS14440	COG2351	hydroxyisourate hydrolase activity
FSC10_RS14445	COG2233	PERMEase
FSC10_RS14460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC10_RS14465	COG4266	Belongs to the allantoicase family
FSC10_RS14490	COG0784	Response regulator, receiver
FSC10_RS14490	COG2205	protein histidine kinase activity
FSC10_RS14520	COG0410	ABC transporter
FSC10_RS14550	COG3150	esterase
FSC10_RS14560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FSC10_RS14565	COG2918	glutathione biosynthetic process
FSC10_RS14580	COG2733	membrane
FSC10_RS14620	COG0753	catalase activity
FSC10_RS14640	COG3830	Belongs to the UPF0237 family
FSC10_RS14640	COG0560	Phosphoserine phosphatase
FSC10_RS14650	COG0385	Bile acid
FSC10_RS14655	COG1335	isochorismatase
FSC10_RS14660	COG2814	Major facilitator Superfamily
FSC10_RS14665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSC10_RS14675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSC10_RS14690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSC10_RS14695	COG3300	MHYT domain
FSC10_RS14695	COG5001	Diguanylate cyclase
FSC10_RS14700	COG2983	Belongs to the UPF0260 family
FSC10_RS14705	COG5487	UPF0391 membrane protein
FSC10_RS14710	COG0728	peptidoglycan biosynthetic process
FSC10_RS14715	COG3023	N-Acetylmuramoyl-L-alanine amidase
FSC10_RS14725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSC10_RS14730	COG1309	transcriptional regulator
FSC10_RS14735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC10_RS14740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC10_RS14745	COG0546	phosphoglycolate phosphatase activity
FSC10_RS14750	COG1028	Short-chain dehydrogenase reductase Sdr
FSC10_RS14770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FSC10_RS14770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSC10_RS14775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC10_RS14780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC10_RS14785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC10_RS14790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC10_RS14795	COG1116	anion transmembrane transporter activity
FSC10_RS14800	COG1309	transcriptional regulator
FSC10_RS14810	COG0196	riboflavin kinase activity
FSC10_RS14815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSC10_RS14825	COG1047	Peptidyl-prolyl cis-trans
FSC10_RS14835	COG2133	pyrroloquinoline quinone binding
FSC10_RS14870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSC10_RS14875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FSC10_RS14880	COG2951	lytic endotransglycosylase activity
FSC10_RS14885	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSC10_RS14905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC10_RS14930	COG2388	GCN5-related N-acetyl-transferase
FSC10_RS14940	COG0861	Integral membrane protein TerC family
FSC10_RS14945	COG0402	S-adenosylhomocysteine deaminase activity
FSC10_RS14985	COG0706	membrane insertase activity
FSC10_RS14990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSC10_RS14995	COG0594	ribonuclease P activity
FSC10_RS15010	COG1192	Involved in chromosome partitioning
FSC10_RS15070	COG4372	Transposase
FSC10_RS15100	COG4372	Transposase
FSC10_RS15170	COG0582	viral genome integration into host DNA
FSC10_RS15185	COG1230	cation diffusion facilitator family transporter
FSC10_RS15220	COG1683	Conserved Protein
FSC10_RS15270	COG4974	Belongs to the 'phage' integrase family
FSC10_RS15295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FSC10_RS15300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC10_RS15380	COG1373	ATPase (AAA superfamily
FSC10_RS15460	COG2826	transposase and inactivated derivatives, IS30 family
FSC10_RS15485	COG1324	tolerance protein
FSC10_RS15490	COG0673	inositol 2-dehydrogenase activity
FSC10_RS15510	COG2826	transposase and inactivated derivatives, IS30 family
FSC10_RS15535	COG1660	Displays ATPase and GTPase activities
FSC10_RS15605	COG2963	transposase activity
FSC10_RS15825	COG3451	type IV secretory pathway VirB4
FSC10_RS15845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FSC10_RS15895	COG1192	Involved in chromosome partitioning
FSC10_RS15985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC10_RS16010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSC10_RS16020	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FSC10_RS16040	COG2076	Multidrug Resistance protein
FSC10_RS16100	COG0488	(ABC) transporter
FSC10_RS16110	COG3173	Aminoglycoside phosphotransferase
FSC10_RS16160	COG3173	Aminoglycoside phosphotransferase
FSC10_RS16250	COG2076	Multidrug Resistance protein