locus-tag	class	description
FSC11_RS00010	COG0592	DNA-directed DNA polymerase activity
FSC11_RS00020	COG0187	DNA topoisomerase II activity
FSC11_RS00030	COG1063	alcohol dehydrogenase
FSC11_RS00035	COG0488	(ABC) transporter
FSC11_RS00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSC11_RS00130	COG2814	Major facilitator Superfamily
FSC11_RS00135	COG2814	Major facilitator Superfamily
FSC11_RS00145	COG3293	Transposase
FSC11_RS00160	COG0693	protein deglycase activity
FSC11_RS00170	COG1012	belongs to the aldehyde dehydrogenase family
FSC11_RS00180	COG0733	neurotransmitter:sodium symporter activity
FSC11_RS00190	COG0428	transporter
FSC11_RS00215	COG0129	dihydroxy-acid dehydratase activity
FSC11_RS00235	COG0583	DNA-binding transcription factor activity
FSC11_RS00240	COG2233	PERMEase
FSC11_RS00255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC11_RS00260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC11_RS00275	COG0783	Belongs to the Dps family
FSC11_RS00295	COG1064	alcohol dehydrogenase
FSC11_RS00300	COG2818	Glycosylase
FSC11_RS00315	COG1194	a g-specific adenine glycosylase
FSC11_RS00330	COG0545	Peptidyl-prolyl cis-trans isomerase
FSC11_RS00355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FSC11_RS00380	COG0438	transferase activity, transferring glycosyl groups
FSC11_RS00390	COG0463	Glycosyl transferase, family 2
FSC11_RS00395	COG0438	transferase activity, transferring glycosyl groups
FSC11_RS00400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC11_RS00410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSC11_RS00420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSC11_RS00435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC11_RS00440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC11_RS00485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSC11_RS00495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FSC11_RS00500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FSC11_RS00505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSC11_RS00550	COG1192	Involved in chromosome partitioning
FSC11_RS00565	COG0586	Pfam SNARE associated Golgi protein
FSC11_RS00570	COG2259	Doxx family
FSC11_RS00580	COG0519	Catalyzes the synthesis of GMP from XMP
FSC11_RS00580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC11_RS00585	COG1715	Restriction endonuclease
FSC11_RS00590	COG3706	GGDEF domain
FSC11_RS00595	COG3706	GGDEF domain
FSC11_RS00640	COG0534	Mate efflux family protein
FSC11_RS00645	COG0436	Aminotransferase
FSC11_RS00650	COG3501	Rhs element vgr protein
FSC11_RS00680	COG2837	iron assimilation
FSC11_RS00690	COG3123	guanosine phosphorylase activity
FSC11_RS00695	COG1683	Conserved Protein
FSC11_RS00700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSC11_RS00705	COG1121	(ABC) transporter
FSC11_RS00755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSC11_RS00775	COG1012	belongs to the aldehyde dehydrogenase family
FSC11_RS00790	COG0386	Belongs to the glutathione peroxidase family
FSC11_RS00795	COG0697	spore germination
FSC11_RS00805	COG0758	DNA mediated transformation
FSC11_RS00855	COG2814	Major facilitator Superfamily
FSC11_RS00875	COG0477	Major facilitator Superfamily
FSC11_RS00880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC11_RS00910	COG1253	flavin adenine dinucleotide binding
FSC11_RS00920	COG2860	membrane
FSC11_RS00925	COG0477	Major facilitator Superfamily
FSC11_RS00935	COG0318	PFAM AMP-dependent synthetase and ligase
FSC11_RS00950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSC11_RS00970	COG0606	chelatase, subunit chli
FSC11_RS00980	COG0347	Belongs to the P(II) protein family
FSC11_RS00985	COG0004	ammonium transporteR
FSC11_RS00995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC11_RS00995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC11_RS01010	COG0586	Pfam SNARE associated Golgi protein
FSC11_RS01030	COG0795	lipopolysaccharide-transporting ATPase activity
FSC11_RS01035	COG0795	lipopolysaccharide-transporting ATPase activity
FSC11_RS01040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSC11_RS01045	COG0793	Belongs to the peptidase S41A family
FSC11_RS01055	COG5002	protein histidine kinase activity
FSC11_RS01060	COG2197	response regulator
FSC11_RS01070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSC11_RS01080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC11_RS01085	COG4974	Belongs to the 'phage' integrase family
FSC11_RS01110	COG0772	Belongs to the SEDS family
FSC11_RS01120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC11_RS01125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSC11_RS01130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSC11_RS01135	COG0494	nUDIX hydrolase
FSC11_RS01140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FSC11_RS01150	COG1538	Outer membrane efflux protein
FSC11_RS01155	COG1216	Glycosyl transferase, family 2
FSC11_RS01165	COG1132	(ABC) transporter
FSC11_RS01175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSC11_RS01185	COG0497	DNA recombination
FSC11_RS01190	COG3123	guanosine phosphorylase activity
FSC11_RS01195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC11_RS01205	COG0237	dephospho-CoA kinase activity
FSC11_RS01230	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FSC11_RS01260	COG0779	Required for maturation of 30S ribosomal subunits
FSC11_RS01265	COG0195	Participates in both transcription termination and antitermination
FSC11_RS01270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSC11_RS01275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSC11_RS01285	COG2212	antiporter activity
FSC11_RS01290	COG1863	multisubunit Na H antiporter MnhE subunit
FSC11_RS01295	COG0651	ATP synthesis coupled electron transport
FSC11_RS01300	COG1006	Multisubunit Na H antiporter MnhC subunit
FSC11_RS01305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC11_RS01305	COG2111	Na H antiporter
FSC11_RS01320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSC11_RS01325	COG4221	oxidoreductase activity
FSC11_RS01335	COG0488	(ABC) transporter
FSC11_RS01375	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC11_RS01395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSC11_RS01400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSC11_RS01405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSC11_RS01410	COG2226	methyltransferase
FSC11_RS01460	COG0069	glutamate synthase activity
FSC11_RS01460	COG0070	glutamate synthase
FSC11_RS01460	COG0067	glutamate synthase
FSC11_RS01465	COG0493	'glutamate synthase
FSC11_RS01470	COG1704	LemA family
FSC11_RS01485	COG4969	Belongs to the N-Me-Phe pilin family
FSC11_RS01495	COG3307	-O-antigen
FSC11_RS01515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC11_RS01520	COG1758	RNA polymerase activity
FSC11_RS01525	COG0194	GDP metabolic process
FSC11_RS01570	COG0228	four-way junction DNA binding
FSC11_RS01575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSC11_RS01585	COG0335	large ribosomal subunit rRNA binding
FSC11_RS01600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC11_RS01605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC11_RS01610	COG5380	lipid catabolic process
FSC11_RS01615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSC11_RS01635	COG5006	permease, DMT superfamily
FSC11_RS01640	COG5006	permease, DMT superfamily
FSC11_RS01645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSC11_RS01650	COG0277	FAD linked oxidase domain protein
FSC11_RS01665	COG2814	Major facilitator Superfamily
FSC11_RS01675	COG0628	permease
FSC11_RS01680	COG1192	Involved in chromosome partitioning
FSC11_RS01695	COG2226	methyltransferase
FSC11_RS01710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSC11_RS01715	COG0254	rRNA binding
FSC11_RS01720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC11_RS01735	COG0534	Mate efflux family protein
FSC11_RS01745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC11_RS01755	COG1278	Cold shock
FSC11_RS01760	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS01775	COG0408	coproporphyrinogen oxidase activity
FSC11_RS01780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC11_RS01805	COG1127	ABC transporter
FSC11_RS01810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSC11_RS01815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSC11_RS01820	COG2854	intermembrane phospholipid transfer
FSC11_RS01830	COG0598	Magnesium transport protein CorA
FSC11_RS01840	COG0494	nUDIX hydrolase
FSC11_RS01845	COG1040	competence protein
FSC11_RS01850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSC11_RS01860	COG2937	Belongs to the GPAT DAPAT family
FSC11_RS01865	COG1946	Acyl-CoA thioesterase
FSC11_RS01870	COG1301	dicarboxylic acid transport
FSC11_RS01890	COG1959	2 iron, 2 sulfur cluster binding
FSC11_RS01900	COG0433	COG0433 Predicted ATPase
FSC11_RS01905	COG0626	cystathionine gamma-synthase activity
FSC11_RS01925	COG0088	Forms part of the polypeptide exit tunnel
FSC11_RS01930	COG0089	rRNA binding
FSC11_RS01940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FSC11_RS01990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSC11_RS01995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSC11_RS02005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSC11_RS02030	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSC11_RS02040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSC11_RS02045	COG0202	RNA polymerase activity
FSC11_RS02050	COG0203	ribosomal protein L17
FSC11_RS02055	COG2072	flavoprotein involved in K transport
FSC11_RS02065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FSC11_RS02100	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FSC11_RS02105	COG0339	signal peptide processing
FSC11_RS02115	COG0557	exoribonuclease II activity
FSC11_RS02150	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSC11_RS02165	COG1295	ribonuclease BN
FSC11_RS02230	COG1702	phosphate starvation-inducible protein PhoH
FSC11_RS02235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSC11_RS02240	COG1196	nuclear chromosome segregation
FSC11_RS02240	COG0741	lytic transglycosylase activity
FSC11_RS02240	COG0739	heme binding
FSC11_RS02280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FSC11_RS02285	COG1183	phosphatidylcholine synthase activity
FSC11_RS02320	COG1283	sodium-dependent phosphate transmembrane transporter activity
FSC11_RS02350	COG1607	acyl-coa hydrolase
FSC11_RS02380	COG2350	Protein conserved in bacteria
FSC11_RS02400	COG3781	membrane
FSC11_RS02405	COG2003	Belongs to the UPF0758 family
FSC11_RS02410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSC11_RS02420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSC11_RS02540	COG1802	Transcriptional regulator
FSC11_RS02540	COG4626	Terminase
FSC11_RS02660	COG2814	Major facilitator Superfamily
FSC11_RS02680	COG0004	ammonium transporteR
FSC11_RS02695	COG3622	Belongs to the hyi family
FSC11_RS02700	COG2084	Dehydrogenase
FSC11_RS02705	COG1024	Enoyl-CoA hydratase
FSC11_RS02710	COG0784	Response regulator, receiver
FSC11_RS02710	COG5002	protein histidine kinase activity
FSC11_RS02710	COG2205	protein histidine kinase activity
FSC11_RS02715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC11_RS02730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC11_RS02740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSC11_RS02750	COG1862	Preprotein translocase
FSC11_RS02765	COG1704	LemA family
FSC11_RS02775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSC11_RS02805	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS02810	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS02820	COG2205	protein histidine kinase activity
FSC11_RS02825	COG0745	RESPONSE REGULATOR receiver
FSC11_RS02830	COG1113	amino acid transport
FSC11_RS02860	COG2096	Adenosyltransferase
FSC11_RS02865	COG4206	TonB-dependent receptor
FSC11_RS02900	COG0159	tryptophan synthase activity
FSC11_RS02910	COG0285	dihydrofolate synthase activity
FSC11_RS02925	COG0450	alkyl hydroperoxide reductase
FSC11_RS02940	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSC11_RS02945	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSC11_RS03015	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSC11_RS03020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSC11_RS03065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC11_RS03070	COG1408	metallophosphoesterase
FSC11_RS03080	COG0477	Major facilitator Superfamily
FSC11_RS03085	COG1272	protein, Hemolysin III
FSC11_RS03105	COG1024	Enoyl-CoA hydratase
FSC11_RS03105	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC11_RS03110	COG0183	Belongs to the thiolase family
FSC11_RS03115	COG2207	Transcriptional regulator
FSC11_RS03125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC11_RS03140	COG0183	Belongs to the thiolase family
FSC11_RS03160	COG0833	amino acid
FSC11_RS03170	COG2233	PERMEase
FSC11_RS03185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC11_RS03200	COG1902	pentaerythritol trinitrate reductase activity
FSC11_RS03220	COG0354	folic acid binding
FSC11_RS03225	COG2132	Multicopper oxidase
FSC11_RS03275	COG0564	pseudouridine synthase activity
FSC11_RS03290	COG2824	Alkylphosphonate utilization operon protein PhnA
FSC11_RS03305	COG0351	phosphomethylpyrimidine kinase
FSC11_RS03305	COG0352	thiamine-phosphate diphosphorylase activity
FSC11_RS03305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC11_RS03320	COG2826	transposase and inactivated derivatives, IS30 family
FSC11_RS03335	COG4772	TonB-dependent receptor
FSC11_RS03340	COG0431	NADPH-dependent FMN reductase
FSC11_RS03345	COG0798	PFAM Bile acid sodium symporter
FSC11_RS03350	COG0640	Transcriptional regulator
FSC11_RS03360	COG2801	Transposase and inactivated derivatives
FSC11_RS03380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC11_RS03395	COG0745	RESPONSE REGULATOR receiver
FSC11_RS03400	COG2205	protein histidine kinase activity
FSC11_RS03410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC11_RS03430	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSC11_RS03445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC11_RS03455	COG0713	ATP synthesis coupled electron transport
FSC11_RS03460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC11_RS03490	COG0583	DNA-binding transcription factor activity
FSC11_RS03505	COG0531	amino acid
FSC11_RS03510	COG4303	Ethanolamine ammonia lyase large subunit
FSC11_RS03515	COG4302	ethanolamine ammonia-lyase activity
FSC11_RS03525	COG0668	transmembrane transport
FSC11_RS03530	COG2081	HI0933 family
FSC11_RS03540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FSC11_RS03555	COG0004	ammonium transporteR
FSC11_RS03585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC11_RS03585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC11_RS03600	COG0489	protein tyrosine kinase activity
FSC11_RS03635	COG0442	prolyl-tRNA aminoacylation
FSC11_RS03645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC11_RS03670	COG0840	transmembrane signaling receptor activity
FSC11_RS03675	COG2198	Histidine kinase
FSC11_RS03675	COG0643	Histidine kinase
FSC11_RS03675	COG0784	Response regulator, receiver
FSC11_RS03760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSC11_RS03770	COG1289	transmembrane transporter activity
FSC11_RS03775	COG2814	Major facilitator Superfamily
FSC11_RS03785	COG0786	glutamate:sodium symporter activity
FSC11_RS03790	COG1115	amino acid carrier protein
FSC11_RS03800	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC11_RS03805	COG1607	acyl-coa hydrolase
FSC11_RS03815	COG2814	Major facilitator Superfamily
FSC11_RS03820	COG0583	DNA-binding transcription factor activity
FSC11_RS03840	COG0523	cobalamin synthesis protein
FSC11_RS03850	COG1285	pathogenesis
FSC11_RS03860	COG3706	GGDEF domain
FSC11_RS03860	COG2203	Gaf domain
FSC11_RS03860	COG5001	Diguanylate cyclase
FSC11_RS03860	COG4251	negative regulation of phosphorylation
FSC11_RS03890	COG0242	peptide deformylase activity
FSC11_RS03895	COG0393	Putative heavy-metal-binding
FSC11_RS03900	COG0393	Putative heavy-metal-binding
FSC11_RS03905	COG1538	Outer membrane efflux protein
FSC11_RS03915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC11_RS03930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSC11_RS03940	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FSC11_RS03950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSC11_RS03955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSC11_RS03955	COG1648	precorrin-2 dehydrogenase activity
FSC11_RS03960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FSC11_RS03970	COG0531	amino acid
FSC11_RS03985	COG0321	lipoyl(octanoyl) transferase activity
FSC11_RS03995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSC11_RS04020	COG0586	Pfam SNARE associated Golgi protein
FSC11_RS04045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSC11_RS04075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSC11_RS04105	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FSC11_RS04115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FSC11_RS04120	COG0358	DNA primase activity
FSC11_RS04130	COG0564	pseudouridine synthase activity
FSC11_RS04155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC11_RS04175	COG0110	maltose O-acetyltransferase activity
FSC11_RS04180	COG0251	oxidation-reduction process
FSC11_RS04185	COG1309	transcriptional regulator
FSC11_RS04195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSC11_RS04200	COG0505	Belongs to the CarA family
FSC11_RS04225	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FSC11_RS04230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC11_RS04240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSC11_RS04275	COG1253	flavin adenine dinucleotide binding
FSC11_RS04295	COG2239	Acts as a magnesium transporter
FSC11_RS04305	COG0501	Belongs to the peptidase M48B family
FSC11_RS04310	COG0739	heme binding
FSC11_RS04310	COG1196	nuclear chromosome segregation
FSC11_RS04310	COG0741	lytic transglycosylase activity
FSC11_RS04315	COG0037	tRNA processing
FSC11_RS04325	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FSC11_RS04330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC11_RS04345	COG0583	DNA-binding transcription factor activity
FSC11_RS04350	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS04355	COG2814	Major facilitator Superfamily
FSC11_RS04360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSC11_RS04370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FSC11_RS04395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC11_RS04400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSC11_RS04405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSC11_RS04410	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FSC11_RS04445	COG1115	amino acid carrier protein
FSC11_RS04450	COG1113	amino acid transport
FSC11_RS04460	COG0019	diaminopimelate decarboxylase activity
FSC11_RS04470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSC11_RS04475	COG0154	amidase activity
FSC11_RS04490	COG1280	lysine exporter protein (LysE YggA)
FSC11_RS04530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC11_RS04555	COG1671	Belongs to the UPF0178 family
FSC11_RS04570	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC11_RS04575	COG1136	(ABC) transporter
FSC11_RS04580	COG0658	competence protein
FSC11_RS04580	COG2333	competence protein COMEC
FSC11_RS04600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSC11_RS04605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSC11_RS04610	COG0628	permease
FSC11_RS04615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC11_RS04645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC11_RS04660	COG2885	chlorophyll binding
FSC11_RS04665	COG0823	Involved in the tonB-independent uptake of proteins
FSC11_RS04685	COG0824	Thioesterase
FSC11_RS04695	COG1473	amidohydrolase
FSC11_RS04710	COG2255	four-way junction helicase activity
FSC11_RS04725	COG0047	phosphoribosylformylglycinamidine synthase activity
FSC11_RS04725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSC11_RS04740	COG0583	DNA-binding transcription factor activity
FSC11_RS04750	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FSC11_RS04755	COG0778	Nitroreductase
FSC11_RS04760	COG1024	Enoyl-CoA hydratase
FSC11_RS04765	COG1051	belongs to the nudix hydrolase family
FSC11_RS04765	COG1056	cytidyltransferase-related domain
FSC11_RS04770	COG2353	YceI-like domain
FSC11_RS04775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSC11_RS04785	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSC11_RS04790	COG0602	queuosine metabolic process
FSC11_RS04805	COG0583	DNA-binding transcription factor activity
FSC11_RS04810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSC11_RS04815	COG4208	sulfate ABC transporter
FSC11_RS04830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC11_RS04835	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC11_RS04845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSC11_RS04870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC11_RS04895	COG0571	ribonuclease III activity
FSC11_RS04900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSC11_RS04910	COG1381	Involved in DNA repair and RecF pathway recombination
FSC11_RS04915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSC11_RS04945	COG0436	Aminotransferase
FSC11_RS04950	COG0024	Methionine aminopeptidase
FSC11_RS04955	COG0052	Belongs to the universal ribosomal protein uS2 family
FSC11_RS04980	COG2951	lytic endotransglycosylase activity
FSC11_RS04995	COG0842	Transport permease protein
FSC11_RS05000	COG1131	(ABC) transporter
FSC11_RS05055	COG1414	Transcriptional regulator
FSC11_RS05060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC11_RS05065	COG1414	Transcriptional regulator
FSC11_RS05070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC11_RS05075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC11_RS05080	COG0183	Belongs to the thiolase family
FSC11_RS05085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSC11_RS05090	COG0596	Alpha beta hydrolase
FSC11_RS05095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSC11_RS05100	COG3485	protocatechuate 3,4-dioxygenase
FSC11_RS05105	COG3485	protocatechuate 3,4-dioxygenase
FSC11_RS05135	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS05145	COG1012	belongs to the aldehyde dehydrogenase family
FSC11_RS05150	COG1024	Enoyl-CoA hydratase
FSC11_RS05155	COG2814	Major facilitator Superfamily
FSC11_RS05170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC11_RS05180	COG0583	DNA-binding transcription factor activity
FSC11_RS05185	COG1053	succinate dehydrogenase
FSC11_RS05230	COG1278	Cold shock
FSC11_RS05285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC11_RS05305	COG3634	alkyl hydroperoxide reductase activity
FSC11_RS05310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC11_RS05320	COG0789	Transcriptional regulator
FSC11_RS05335	COG1720	tRNA m6t6A37 methyltransferase activity
FSC11_RS05345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSC11_RS05355	COG0745	RESPONSE REGULATOR receiver
FSC11_RS05360	COG0642	Histidine kinase
FSC11_RS05370	COG0494	nUDIX hydrolase
FSC11_RS05380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC11_RS05385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSC11_RS05390	COG3139	Protein of unknown function (DUF1315)
FSC11_RS05400	COG1301	dicarboxylic acid transport
FSC11_RS05405	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS05410	COG0693	protein deglycase activity
FSC11_RS05420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSC11_RS05425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSC11_RS05450	COG2252	PERMEase
FSC11_RS05455	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSC11_RS05470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSC11_RS05480	COG0527	aspartate kinase activity
FSC11_RS05495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSC11_RS05510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSC11_RS05525	COG1047	Peptidyl-prolyl cis-trans
FSC11_RS05530	COG1252	NADH dehydrogenase
FSC11_RS05550	COG2351	hydroxyisourate hydrolase activity
FSC11_RS05570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC11_RS05570	COG2755	lipolytic protein G-D-S-L family
FSC11_RS05575	COG0436	Aminotransferase
FSC11_RS05580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSC11_RS05585	COG0386	Belongs to the glutathione peroxidase family
FSC11_RS05595	COG0436	Aminotransferase
FSC11_RS05600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSC11_RS05620	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FSC11_RS05640	COG0012	GTP binding
FSC11_RS05645	COG2011	ABC-type metal ion transport system permease component
FSC11_RS05650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC11_RS05655	COG1464	Belongs to the NlpA lipoprotein family
FSC11_RS05705	COG1454	alcohol dehydrogenase
FSC11_RS05735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSC11_RS05735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSC11_RS05770	COG3634	alkyl hydroperoxide reductase activity
FSC11_RS05800	COG1643	Atp-dependent helicase
FSC11_RS05820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC11_RS05825	COG2707	UPF0756 membrane protein
FSC11_RS05845	COG0564	pseudouridine synthase activity
FSC11_RS05850	COG0802	atpase or kinase
FSC11_RS05855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSC11_RS05865	COG1923	regulation of RNA biosynthetic process
FSC11_RS05870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC11_RS05880	COG3178	'Phosphotransferase
FSC11_RS05885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSC11_RS05895	COG1192	Involved in chromosome partitioning
FSC11_RS05900	COG1475	DNA binding
FSC11_RS05905	COG0811	peptide transport
FSC11_RS05915	COG1132	(ABC) transporter
FSC11_RS05920	COG1663	tetraacyldisaccharide 4'-kinase activity
FSC11_RS05940	COG0084	hydrolase, TatD family'
FSC11_RS05975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSC11_RS06005	COG0776	regulation of translation
FSC11_RS06025	COG2431	L-lysine efflux transmembrane transporter activity
FSC11_RS06040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSC11_RS06065	COG1253	flavin adenine dinucleotide binding
FSC11_RS06095	COG0308	aminopeptidase N
FSC11_RS06105	COG0589	response to stress
FSC11_RS06110	COG0589	response to stress
FSC11_RS06120	COG3135	benzoate transporter
FSC11_RS06130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSC11_RS06145	COG0183	Belongs to the thiolase family
FSC11_RS06170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSC11_RS06175	COG0824	Thioesterase
FSC11_RS06180	COG1454	alcohol dehydrogenase
FSC11_RS06185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSC11_RS06205	COG0069	glutamate synthase activity
FSC11_RS06215	COG2308	Evidence 4 Homologs of previously reported genes of
FSC11_RS06225	COG1305	Transglutaminase-like
FSC11_RS06240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSC11_RS06260	COG0360	Binds together with S18 to 16S ribosomal RNA
FSC11_RS06270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FSC11_RS06275	COG1845	cytochrome c oxidase, subunit III
FSC11_RS06280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSC11_RS06285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSC11_RS06310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC11_RS06325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSC11_RS06330	COG2890	protein-(glutamine-N5) methyltransferase activity
FSC11_RS06335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC11_RS06340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC11_RS06370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSC11_RS06395	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FSC11_RS06400	COG0477	Major facilitator Superfamily
FSC11_RS06405	COG0729	surface antigen
FSC11_RS06420	COG1570	exodeoxyribonuclease VII activity
FSC11_RS06445	COG0444	Belongs to the ABC transporter superfamily
FSC11_RS06465	COG0786	glutamate:sodium symporter activity
FSC11_RS06470	COG3300	MHYT domain
FSC11_RS06470	COG5001	Diguanylate cyclase
FSC11_RS06495	COG0024	Methionine aminopeptidase
FSC11_RS06500	COG0583	DNA-binding transcription factor activity
FSC11_RS06505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSC11_RS06520	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC11_RS06520	COG1902	pentaerythritol trinitrate reductase activity
FSC11_RS06550	COG0148	phosphopyruvate hydratase activity
FSC11_RS06555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FSC11_RS06565	COG0772	Belongs to the SEDS family
FSC11_RS06585	COG4890	Cyd operon protein YbgT
FSC11_RS06590	COG1294	oxidase, subunit
FSC11_RS06640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSC11_RS06660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC11_RS06670	COG0133	tryptophan synthase activity
FSC11_RS06675	COG0517	IMP dehydrogenase activity
FSC11_RS06705	COG0612	Peptidase, M16
FSC11_RS06710	COG0552	protein localization to endoplasmic reticulum
FSC11_RS06785	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS06790	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS06850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC11_RS06855	COG0730	response to heat
FSC11_RS06860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC11_RS06865	COG2207	Transcriptional regulator
FSC11_RS06870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC11_RS06875	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS06880	COG2169	Transcriptional regulator
FSC11_RS06900	COG1525	nuclease
FSC11_RS06950	COG2076	Multidrug Resistance protein
FSC11_RS06980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC11_RS06985	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSC11_RS06995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC11_RS07010	COG2814	Major facilitator Superfamily
FSC11_RS07015	COG0509	glycine decarboxylation via glycine cleavage system
FSC11_RS07025	COG2030	dehydratase
FSC11_RS07030	COG1132	(ABC) transporter
FSC11_RS07035	COG0668	transmembrane transport
FSC11_RS07050	COG3122	Protein conserved in bacteria
FSC11_RS07055	COG3619	membrane
FSC11_RS07070	COG0640	Transcriptional regulator
FSC11_RS07075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC11_RS07085	COG0789	Transcriptional regulator
FSC11_RS07110	COG0830	nickel cation binding
FSC11_RS07120	COG0829	nickel cation binding
FSC11_RS07135	COG0804	urea catabolic process
FSC11_RS07150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC11_RS07155	COG0183	Belongs to the thiolase family
FSC11_RS07160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC11_RS07165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC11_RS07170	COG3135	benzoate transporter
FSC11_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS07180	COG0543	2 iron, 2 sulfur cluster binding
FSC11_RS07180	COG0633	Ferredoxin
FSC11_RS07185	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FSC11_RS07190	COG4638	Rieske (2fe-2S)
FSC11_RS07200	COG4829	muconolactone delta-isomerase
FSC11_RS07205	COG4948	Mandelate Racemase Muconate Lactonizing
FSC11_RS07210	COG0583	DNA-binding transcription factor activity
FSC11_RS07215	COG2814	Major facilitator Superfamily
FSC11_RS07225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSC11_RS07230	COG0318	PFAM AMP-dependent synthetase and ligase
FSC11_RS07235	COG1017	nitric oxide dioxygenase activity
FSC11_RS07235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC11_RS07250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC11_RS07255	COG0583	DNA-binding transcription factor activity
FSC11_RS07270	COG0439	Biotin carboxylase
FSC11_RS07285	COG0864	Transcriptional regulator
FSC11_RS07310	COG1064	alcohol dehydrogenase
FSC11_RS07330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC11_RS07335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC11_RS07340	COG1116	anion transmembrane transporter activity
FSC11_RS07340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC11_RS07350	COG2223	nitrite transmembrane transporter activity
FSC11_RS07355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC11_RS07360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC11_RS07365	COG0243	molybdopterin cofactor binding
FSC11_RS07375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSC11_RS07385	COG0314	molybdopterin synthase activity
FSC11_RS07390	COG0315	cyclic pyranopterin monophosphate synthase activity
FSC11_RS07390	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSC11_RS07395	COG0303	'Molybdopterin
FSC11_RS07400	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSC11_RS07405	COG4149	molybdate abc transporter
FSC11_RS07410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FSC11_RS07415	COG2223	nitrite transmembrane transporter activity
FSC11_RS07425	COG0347	Belongs to the P(II) protein family
FSC11_RS07445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC11_RS07450	COG1309	transcriptional regulator
FSC11_RS07470	COG1944	ATP diphosphatase activity
FSC11_RS07485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC11_RS07500	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FSC11_RS07505	COG1877	trehalose-phosphatase activity
FSC11_RS07515	COG0583	DNA-binding transcription factor activity
FSC11_RS07525	COG0583	DNA-binding transcription factor activity
FSC11_RS07570	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FSC11_RS07575	COG2116	formate transmembrane transporter activity
FSC11_RS07580	COG0515	serine threonine protein kinase
FSC11_RS07600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSC11_RS07605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC11_RS07620	COG2194	sulfuric ester hydrolase activity
FSC11_RS07625	COG0745	RESPONSE REGULATOR receiver
FSC11_RS07630	COG0642	Histidine kinase
FSC11_RS07675	COG3550	peptidyl-serine autophosphorylation
FSC11_RS07680	COG2801	Transposase and inactivated derivatives
FSC11_RS07690	COG0596	Alpha beta hydrolase
FSC11_RS07720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC11_RS07725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FSC11_RS07750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FSC11_RS07760	COG0511	ligase activity, forming carbon-carbon bonds
FSC11_RS07765	COG0439	Biotin carboxylase
FSC11_RS07775	COG3706	GGDEF domain
FSC11_RS07785	COG2814	Major facilitator Superfamily
FSC11_RS07820	COG1546	Belongs to the CinA family
FSC11_RS07820	COG1058	Belongs to the CinA family
FSC11_RS07830	COG0372	Belongs to the citrate synthase family
FSC11_RS07850	COG0477	Major facilitator Superfamily
FSC11_RS07865	COG0542	response to heat
FSC11_RS07870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSC11_RS07895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC11_RS07905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSC11_RS07910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSC11_RS07915	COG0569	domain protein
FSC11_RS07920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSC11_RS07940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSC11_RS07950	COG1585	Membrane protein implicated in regulation of membrane protease activity
FSC11_RS07970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC11_RS07975	COG0776	regulation of translation
FSC11_RS08000	COG0822	iron-sulfur transferase activity
FSC11_RS08005	COG0316	Belongs to the HesB IscA family
FSC11_RS08035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSC11_RS08045	COG1027	Aspartate ammonia-lyase
FSC11_RS08050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC11_RS08060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC11_RS08060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC11_RS08060	COG0506	proline dehydrogenase activity
FSC11_RS08080	COG3781	membrane
FSC11_RS08085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC11_RS08120	COG0697	spore germination
FSC11_RS08145	COG0424	maF-like protein
FSC11_RS08155	COG2850	peptidyl-arginine hydroxylation
FSC11_RS08160	COG0625	glutathione transferase activity
FSC11_RS08165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC11_RS08170	COG0702	epimerase
FSC11_RS08175	COG0268	Binds directly to 16S ribosomal RNA
FSC11_RS08190	COG1011	Hydrolase
FSC11_RS08195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSC11_RS08205	COG2137	regulation of response to DNA damage stimulus
FSC11_RS08220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC11_RS08225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSC11_RS08230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC11_RS08240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC11_RS08255	COG0575	Belongs to the CDS family
FSC11_RS08260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSC11_RS08280	COG3852	Histidine kinase
FSC11_RS08300	COG0445	tRNA wobble uridine modification
FSC11_RS08330	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FSC11_RS08335	COG0138	bifunctional purine biosynthesis protein purh
FSC11_RS08355	COG1464	Belongs to the NlpA lipoprotein family
FSC11_RS08360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC11_RS08365	COG2011	ABC-type metal ion transport system permease component
FSC11_RS08395	COG4251	negative regulation of phosphorylation
FSC11_RS08395	COG2203	Gaf domain
FSC11_RS08395	COG3706	GGDEF domain
FSC11_RS08395	COG5001	Diguanylate cyclase
FSC11_RS08415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FSC11_RS08525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSC11_RS08535	COG4122	O-methyltransferase activity
FSC11_RS08540	COG0589	response to stress
FSC11_RS08565	COG1538	Outer membrane efflux protein
FSC11_RS08570	COG1137	ATPase activity
FSC11_RS08575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FSC11_RS08585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FSC11_RS08590	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSC11_RS08590	COG0517	IMP dehydrogenase activity
FSC11_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS08635	COG0519	Catalyzes the synthesis of GMP from XMP
FSC11_RS08635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC11_RS08640	COG2353	YceI-like domain
FSC11_RS08645	COG0456	acetyltransferase
FSC11_RS08655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSC11_RS08660	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSC11_RS08750	COG2755	lipolytic protein G-D-S-L family
FSC11_RS08750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC11_RS08845	COG2369	cell adhesion
FSC11_RS08850	COG3567	Phage-associated protein, HI1409 family
FSC11_RS08855	COG5410	chromosome segregation
FSC11_RS09040	COG1309	transcriptional regulator
FSC11_RS09095	COG0352	thiamine-phosphate diphosphorylase activity
FSC11_RS09110	COG3025	triphosphatase activity
FSC11_RS09130	COG3618	amidohydrolase
FSC11_RS09135	COG0612	Peptidase, M16
FSC11_RS09145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC11_RS09150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC11_RS09200	COG2815	serine threonine protein kinase
FSC11_RS09200	COG0515	serine threonine protein kinase
FSC11_RS09255	COG4783	chaperone-mediated protein folding
FSC11_RS09310	COG0778	Nitroreductase
FSC11_RS09320	COG0513	Belongs to the DEAD box helicase family
FSC11_RS09325	COG1278	Cold shock
FSC11_RS09340	COG2363	Small membrane protein
FSC11_RS09360	COG0659	secondary active sulfate transmembrane transporter activity
FSC11_RS09365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSC11_RS09385	COG3047	cAMP biosynthetic process
FSC11_RS09385	COG2885	chlorophyll binding
FSC11_RS09395	COG0540	Belongs to the ATCase OTCase family
FSC11_RS09415	COG0667	Aldo Keto reductase
FSC11_RS09425	COG1765	OsmC-like protein
FSC11_RS09430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC11_RS09450	COG1136	(ABC) transporter
FSC11_RS09455	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC11_RS09460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC11_RS09465	COG0281	malic enzyme
FSC11_RS09485	COG0714	Associated with various cellular activities
FSC11_RS09490	COG2879	small protein
FSC11_RS09495	COG1966	Carbon starvation protein
FSC11_RS09500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSC11_RS09540	COG1067	ATP-dependent peptidase activity
FSC11_RS09545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FSC11_RS09550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSC11_RS09555	COG0583	DNA-binding transcription factor activity
FSC11_RS09580	COG1686	Belongs to the peptidase S11 family
FSC11_RS09585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSC11_RS09600	COG2351	hydroxyisourate hydrolase activity
FSC11_RS09615	COG5002	protein histidine kinase activity
FSC11_RS09655	COG0616	signal peptide processing
FSC11_RS09665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSC11_RS09675	COG0573	inorganic phosphate transmembrane transporter activity
FSC11_RS09685	COG0076	glutamate decarboxylase activity
FSC11_RS09690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSC11_RS09700	COG0671	phosphoesterase, PA-phosphatase related
FSC11_RS09705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSC11_RS09715	COG2814	Major facilitator Superfamily
FSC11_RS09725	COG1733	regulation of RNA biosynthetic process
FSC11_RS09750	COG0556	nucleotide-excision repair
FSC11_RS09785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC11_RS09790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC11_RS09795	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS09805	COG2084	Dehydrogenase
FSC11_RS09810	COG2233	PERMEase
FSC11_RS09815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC11_RS09820	COG0251	oxidation-reduction process
FSC11_RS09825	COG1335	isochorismatase
FSC11_RS09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC11_RS09835	COG0596	Alpha beta hydrolase
FSC11_RS09845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC11_RS09850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FSC11_RS09855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSC11_RS09895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FSC11_RS09900	COG3161	chorismate lyase activity
FSC11_RS09910	COG0174	glutamine synthetase
FSC11_RS09915	COG0512	Glutamine amidotransferase of anthranilate synthase
FSC11_RS09920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSC11_RS09935	COG0302	gtp cyclohydrolase
FSC11_RS09950	COG3706	GGDEF domain
FSC11_RS09965	COG3739	integral membrane protein
FSC11_RS09980	COG1741	Belongs to the pirin family
FSC11_RS09995	COG2197	response regulator
FSC11_RS10000	COG4585	Histidine kinase
FSC11_RS10020	COG0640	Transcriptional regulator
FSC11_RS10035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSC11_RS10040	COG4232	protein-disulfide reductase activity
FSC11_RS10050	COG0642	Histidine kinase
FSC11_RS10060	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC11_RS10060	COG1902	pentaerythritol trinitrate reductase activity
FSC11_RS10070	COG0277	FAD linked oxidase domain protein
FSC11_RS10080	COG2186	Transcriptional regulator
FSC11_RS10085	COG1620	l-lactate permease
FSC11_RS10100	COG5001	Diguanylate cyclase
FSC11_RS10100	COG3706	GGDEF domain
FSC11_RS10100	COG4251	negative regulation of phosphorylation
FSC11_RS10100	COG2203	Gaf domain
FSC11_RS10105	COG0418	dihydroorotase activity
FSC11_RS10110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSC11_RS10120	COG4771	TonB-dependent receptor
FSC11_RS10130	COG0833	amino acid
FSC11_RS10175	COG4172	Belongs to the ABC transporter superfamily
FSC11_RS10180	COG4239	(ABC) transporter, permease
FSC11_RS10185	COG4174	ABC transporter (Permease)
FSC11_RS10190	COG4166	transmembrane transport
FSC11_RS10195	COG0741	lytic transglycosylase activity
FSC11_RS10195	COG1388	LysM domain
FSC11_RS10245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC11_RS10250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC11_RS10265	COG2155	Conserved Protein
FSC11_RS10275	COG0006	proline dipeptidase activity
FSC11_RS10310	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSC11_RS10320	COG2234	aminopeptidase activity
FSC11_RS10330	COG3384	dioxygenase
FSC11_RS10340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSC11_RS10345	COG2878	Part of a membrane complex involved in electron transport
FSC11_RS10350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSC11_RS10375	COG0768	penicillin binding
FSC11_RS10380	COG0742	ribosomal rna small subunit methyltransferase
FSC11_RS10450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSC11_RS10470	COG4221	oxidoreductase activity
FSC11_RS10470	COG3321	synthase
FSC11_RS10470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC11_RS10470	COG0604	alcohol dehydrogenase
FSC11_RS10515	COG2268	Band 7 protein
FSC11_RS10520	COG0726	polysaccharide deacetylase
FSC11_RS10520	COG1649	PFAM Uncharacterised BCR, COG1649
FSC11_RS10530	COG1215	transferase activity, transferring glycosyl groups
FSC11_RS10535	COG0726	polysaccharide deacetylase
FSC11_RS10535	COG1649	PFAM Uncharacterised BCR, COG1649
FSC11_RS10545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSC11_RS10555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC11_RS10570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSC11_RS10575	COG1053	succinate dehydrogenase
FSC11_RS10580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FSC11_RS10600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC11_RS10600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSC11_RS10635	COG2321	neutral zinc metallopeptidase
FSC11_RS10640	COG2354	Protein conserved in bacteria
FSC11_RS10660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSC11_RS10665	COG1773	rubredoxin
FSC11_RS10670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC11_RS10680	COG0583	DNA-binding transcription factor activity
FSC11_RS10690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC11_RS10700	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FSC11_RS10705	COG4181	ATPase activity
FSC11_RS10730	COG0500	methyltransferase
FSC11_RS10735	COG4771	TonB-dependent receptor
FSC11_RS10755	COG0306	phosphate transporter
FSC11_RS10775	COG2376	Dihydroxyacetone kinase
FSC11_RS10780	COG2066	Belongs to the glutaminase family
FSC11_RS10785	COG0300	oxidoreductase activity
FSC11_RS10795	COG0525	valine-tRNA ligase activity
FSC11_RS10805	COG2852	Protein conserved in bacteria
FSC11_RS10820	COG2323	membrane
FSC11_RS10825	COG0546	phosphoglycolate phosphatase activity
FSC11_RS10845	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC11_RS10860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC11_RS10865	COG0142	geranyltranstransferase activity
FSC11_RS10870	COG2828	Protein conserved in bacteria
FSC11_RS10875	COG1113	amino acid transport
FSC11_RS10905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC11_RS10910	COG1530	ribonuclease E activity
FSC11_RS10915	COG0424	maF-like protein
FSC11_RS10920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FSC11_RS10925	COG1792	Involved in formation and maintenance of cell shape
FSC11_RS10930	COG1077	Cell shape determining protein MreB Mrl
FSC11_RS10935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC11_RS10945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC11_RS10965	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FSC11_RS10980	COG1294	oxidase, subunit
FSC11_RS10985	COG1271	oxidase subunit
FSC11_RS11005	COG4106	trans-aconitate 2-methyltransferase activity
FSC11_RS11020	COG0596	Alpha beta hydrolase
FSC11_RS11025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FSC11_RS11045	COG1113	amino acid transport
FSC11_RS11050	COG1448	Aminotransferase
FSC11_RS11065	COG0625	glutathione transferase activity
FSC11_RS11080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC11_RS11085	COG3177	Filamentation induced by cAMP protein fic
FSC11_RS11160	COG3586	endonuclease activity
FSC11_RS11225	COG0582	viral genome integration into host DNA
FSC11_RS11235	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSC11_RS11240	COG2050	protein possibly involved in aromatic compounds catabolism
FSC11_RS11265	COG0420	3'-5' exonuclease activity
FSC11_RS11295	COG0735	belongs to the Fur family
FSC11_RS11300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC11_RS11305	COG2914	Belongs to the UPF0125 (RnfH) family
FSC11_RS11320	COG0121	glutamine amidotransferase
FSC11_RS11330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC11_RS11335	COG0756	dUTP diphosphatase activity
FSC11_RS11345	COG2885	chlorophyll binding
FSC11_RS11350	COG0204	Acyl-transferase
FSC11_RS11380	COG0531	amino acid
FSC11_RS11380	COG1674	ftsk spoiiie
FSC11_RS11385	COG0492	ferredoxin-NADP+ reductase activity
FSC11_RS11390	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSC11_RS11395	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FSC11_RS11400	COG0456	acetyltransferase
FSC11_RS11410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSC11_RS11415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSC11_RS11425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSC11_RS11445	COG1113	amino acid transport
FSC11_RS11450	COG0251	oxidation-reduction process
FSC11_RS11470	COG1652	LysM domain
FSC11_RS11475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSC11_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS11495	COG1399	metal-binding, possibly nucleic acid-binding protein
FSC11_RS11500	COG3101	peptidyl-lysine hydroxylation
FSC11_RS11505	COG0009	L-threonylcarbamoyladenylate synthase
FSC11_RS11525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSC11_RS11530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSC11_RS11545	COG2193	ferroxidase activity
FSC11_RS11550	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FSC11_RS11555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSC11_RS11565	COG1196	nuclear chromosome segregation
FSC11_RS11575	COG0730	response to heat
FSC11_RS11580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FSC11_RS11580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FSC11_RS11590	COG3545	Serine hydrolase
FSC11_RS11595	COG3545	Serine hydrolase
FSC11_RS11600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSC11_RS11645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSC11_RS11655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSC11_RS11670	COG4269	membrane
FSC11_RS11690	COG1968	undecaprenyl-diphosphatase activity
FSC11_RS11695	COG1214	PFAM Peptidase M22, glycoprotease
FSC11_RS11705	COG0494	nUDIX hydrolase
FSC11_RS11720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSC11_RS11745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC11_RS11750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC11_RS11760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSC11_RS11765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSC11_RS11770	COG0625	glutathione transferase activity
FSC11_RS11775	COG2969	positive regulation of protein catabolic process
FSC11_RS11825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC11_RS11830	COG1764	response to oxidative stress
FSC11_RS11875	COG0037	tRNA processing
FSC11_RS11885	COG0248	Ppx GppA phosphatase
FSC11_RS11910	COG0072	phenylalanine-tRNA ligase activity
FSC11_RS11915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSC11_RS11945	COG1238	metal cluster binding
FSC11_RS11955	COG0625	glutathione transferase activity
FSC11_RS11965	COG0546	phosphoglycolate phosphatase activity
FSC11_RS11990	COG0318	PFAM AMP-dependent synthetase and ligase
FSC11_RS12010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSC11_RS12025	COG1215	transferase activity, transferring glycosyl groups
FSC11_RS12055	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSC11_RS12105	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSC11_RS12125	COG1660	Displays ATPase and GTPase activities
FSC11_RS12140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSC11_RS12145	COG0617	tRNA 3'-terminal CCA addition
FSC11_RS12150	COG1555	photosystem II stabilization
FSC11_RS12155	COG3956	TIGRFAM MazG family protein
FSC11_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS12175	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC11_RS12185	COG0124	histidyl-tRNA synthetase
FSC11_RS12195	COG1426	Protein conserved in bacteria
FSC11_RS12215	COG2975	iron-sulfur cluster assembly
FSC11_RS12250	COG0440	acetolactate synthase activity
FSC11_RS12255	COG0028	Belongs to the TPP enzyme family
FSC11_RS12280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC11_RS12285	COG0577	efflux transmembrane transporter activity
FSC11_RS12285	COG1136	(ABC) transporter
FSC11_RS12290	COG1538	Outer membrane efflux protein
FSC11_RS12300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FSC11_RS12310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSC11_RS12315	COG1162	GTPase activity
FSC11_RS12345	COG0084	hydrolase, TatD family'
FSC11_RS12360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSC11_RS12375	COG0793	Belongs to the peptidase S41A family
FSC11_RS12400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSC11_RS12405	COG0280	phosphate acetyltransferase
FSC11_RS12405	COG0857	belongs to the CobB CobQ family
FSC11_RS12410	COG2610	gluconate transmembrane transporter activity
FSC11_RS12415	COG1454	alcohol dehydrogenase
FSC11_RS12425	COG1414	Transcriptional regulator
FSC11_RS12435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC11_RS12435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC11_RS12450	COG0740	serine-type endopeptidase activity
FSC11_RS12460	COG4771	TonB-dependent receptor
FSC11_RS12465	COG4774	siderophore transport
FSC11_RS12470	COG4774	siderophore transport
FSC11_RS12475	COG3128	pkhd-type hydroxylase
FSC11_RS12485	COG4774	siderophore transport
FSC11_RS12490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSC11_RS12500	COG2813	Specifically methylates the guanine in position
FSC11_RS12500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC11_RS12550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FSC11_RS12565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FSC11_RS12575	COG0411	ABC transporter
FSC11_RS12595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC11_RS12615	COG4638	Rieske (2fe-2S)
FSC11_RS12635	COG0154	amidase activity
FSC11_RS12645	COG0583	DNA-binding transcription factor activity
FSC11_RS12650	COG4948	Mandelate Racemase Muconate Lactonizing
FSC11_RS12655	COG4829	muconolactone delta-isomerase
FSC11_RS12665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC11_RS12670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC11_RS12680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC11_RS12690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSC11_RS12725	COG0788	formyltetrahydrofolate deformylase activity
FSC11_RS12750	COG4651	solute:proton antiporter activity
FSC11_RS12750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSC11_RS12770	COG0724	RNA recognition motif
FSC11_RS12775	COG0210	DNA helicase
FSC11_RS12780	COG1929	Belongs to the glycerate kinase type-1 family
FSC11_RS12810	COG2900	Belongs to the SlyX family
FSC11_RS12820	COG1560	Kdo2-lipid A biosynthetic process
FSC11_RS12850	COG0252	asparaginase activity
FSC11_RS12880	COG0473	3-isopropylmalate dehydrogenase activity
FSC11_RS12895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSC11_RS12940	COG1960	acyl-CoA dehydrogenase activity
FSC11_RS12945	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FSC11_RS12955	COG0519	Catalyzes the synthesis of GMP from XMP
FSC11_RS12965	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC11_RS12970	COG3384	dioxygenase
FSC11_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS12990	COG4638	Rieske (2fe-2S)
FSC11_RS12995	COG0583	DNA-binding transcription factor activity
FSC11_RS13015	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSC11_RS13020	COG3971	2-oxopent-4-enoate hydratase activity
FSC11_RS13025	COG0546	phosphoglycolate phosphatase activity
FSC11_RS13035	COG1530	ribonuclease E activity
FSC11_RS13040	COG0318	PFAM AMP-dependent synthetase and ligase
FSC11_RS13065	COG1983	PspC domain protein
FSC11_RS13075	COG0471	metal ion transport
FSC11_RS13095	COG0751	glycine-tRNA ligase activity
FSC11_RS13120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC11_RS13150	COG0493	'glutamate synthase
FSC11_RS13160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FSC11_RS13175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC11_RS13190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSC11_RS13200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSC11_RS13200	COG0644	oxidoreductase
FSC11_RS13220	COG3501	Rhs element vgr protein
FSC11_RS13230	COG4535	Mg2 and Co2 transporter CorC
FSC11_RS13235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSC11_RS13255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSC11_RS13265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSC11_RS13280	COG0789	Transcriptional regulator
FSC11_RS13285	COG2841	Protein conserved in bacteria
FSC11_RS13290	COG1185	polyribonucleotide nucleotidyltransferase activity
FSC11_RS13295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSC11_RS13300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC11_RS13305	COG1074	ATP-dependent DNA helicase activity
FSC11_RS13310	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSC11_RS13345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC11_RS13375	COG0745	RESPONSE REGULATOR receiver
FSC11_RS13380	COG2205	protein histidine kinase activity
FSC11_RS13385	COG0427	acetyl-CoA hydrolase
FSC11_RS13395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSC11_RS13420	COG0326	Molecular chaperone. Has ATPase activity
FSC11_RS13435	COG2056	Na+-H+ antiporter family
FSC11_RS13475	COG4372	Transposase
FSC11_RS13480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSC11_RS13485	COG0085	RNA polymerase activity
FSC11_RS13490	COG0222	ribosome binding
FSC11_RS13495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FSC11_RS13500	COG0081	regulation of translation
FSC11_RS13505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSC11_RS13525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSC11_RS13555	COG0546	phosphoglycolate phosphatase activity
FSC11_RS13585	COG0824	Thioesterase
FSC11_RS13605	COG0181	hydroxymethylbilane synthase activity
FSC11_RS13615	COG3275	phosphorelay sensor kinase activity
FSC11_RS13630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSC11_RS13640	COG0322	excinuclease ABC activity
FSC11_RS13655	COG3706	GGDEF domain
FSC11_RS13660	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC11_RS13660	COG1024	Enoyl-CoA hydratase
FSC11_RS13720	COG0131	Imidazoleglycerol-phosphate dehydratase
FSC11_RS13725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSC11_RS13770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FSC11_RS13775	COG0107	imidazoleglycerol-phosphate synthase activity
FSC11_RS13805	COG3158	transport of potassium into the cell
FSC11_RS13835	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FSC11_RS13865	COG2814	Major facilitator Superfamily
FSC11_RS13875	COG0352	thiamine-phosphate diphosphorylase activity
FSC11_RS13875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC11_RS13875	COG0351	phosphomethylpyrimidine kinase
FSC11_RS13880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSC11_RS13885	COG3706	GGDEF domain
FSC11_RS13900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC11_RS13905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC11_RS13910	COG3162	membrane
FSC11_RS13915	COG0784	Response regulator, receiver
FSC11_RS13915	COG2205	protein histidine kinase activity
FSC11_RS13930	COG0431	NADPH-dependent FMN reductase
FSC11_RS13940	COG0307	riboflavin synthase, alpha
FSC11_RS13955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC11_RS13965	COG0668	transmembrane transport
FSC11_RS13970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC11_RS13975	COG1519	Transferase
FSC11_RS13980	COG1902	pentaerythritol trinitrate reductase activity
FSC11_RS13985	COG0640	Transcriptional regulator
FSC11_RS14005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSC11_RS14015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC11_RS14030	COG0426	domain, Protein
FSC11_RS14030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC11_RS14035	COG2119	membrane
FSC11_RS14065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSC11_RS14075	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FSC11_RS14100	COG0189	ligase activity
FSC11_RS14115	COG2132	Multicopper oxidase
FSC11_RS14125	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS14140	COG0708	Exodeoxyribonuclease III
FSC11_RS14145	COG1393	Belongs to the ArsC family
FSC11_RS14195	COG2351	hydroxyisourate hydrolase activity
FSC11_RS14200	COG2233	PERMEase
FSC11_RS14215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC11_RS14220	COG4266	Belongs to the allantoicase family
FSC11_RS14245	COG2205	protein histidine kinase activity
FSC11_RS14245	COG0784	Response regulator, receiver
FSC11_RS14275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC11_RS14300	COG3150	esterase
FSC11_RS14315	COG2918	glutathione biosynthetic process
FSC11_RS14330	COG2733	membrane
FSC11_RS14370	COG0753	catalase activity
FSC11_RS14390	COG0560	Phosphoserine phosphatase
FSC11_RS14390	COG3830	Belongs to the UPF0237 family
FSC11_RS14400	COG0385	Bile acid
FSC11_RS14405	COG1335	isochorismatase
FSC11_RS14410	COG2814	Major facilitator Superfamily
FSC11_RS14415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSC11_RS14425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSC11_RS14440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSC11_RS14445	COG5001	Diguanylate cyclase
FSC11_RS14445	COG3300	MHYT domain
FSC11_RS14450	COG2983	Belongs to the UPF0260 family
FSC11_RS14455	COG5487	UPF0391 membrane protein
FSC11_RS14460	COG0728	peptidoglycan biosynthetic process
FSC11_RS14465	COG3023	N-Acetylmuramoyl-L-alanine amidase
FSC11_RS14475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSC11_RS14480	COG1309	transcriptional regulator
FSC11_RS14485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC11_RS14490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC11_RS14495	COG0546	phosphoglycolate phosphatase activity
FSC11_RS14500	COG1028	Short-chain dehydrogenase reductase Sdr
FSC11_RS14520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FSC11_RS14520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSC11_RS14525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC11_RS14530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC11_RS14535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC11_RS14540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC11_RS14545	COG1116	anion transmembrane transporter activity
FSC11_RS14550	COG1309	transcriptional regulator
FSC11_RS14560	COG0196	riboflavin kinase activity
FSC11_RS14565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSC11_RS14575	COG1047	Peptidyl-prolyl cis-trans
FSC11_RS14585	COG2133	pyrroloquinoline quinone binding
FSC11_RS14620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSC11_RS14625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FSC11_RS14630	COG2951	lytic endotransglycosylase activity
FSC11_RS14635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSC11_RS14655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC11_RS14680	COG2388	GCN5-related N-acetyl-transferase
FSC11_RS14690	COG0861	Integral membrane protein TerC family
FSC11_RS14695	COG0402	S-adenosylhomocysteine deaminase activity
FSC11_RS14735	COG0706	membrane insertase activity
FSC11_RS14740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSC11_RS14745	COG0594	ribonuclease P activity
FSC11_RS14835	COG2963	transposase activity
FSC11_RS14910	COG2826	transposase and inactivated derivatives, IS30 family
FSC11_RS14930	COG0673	inositol 2-dehydrogenase activity
FSC11_RS14945	COG1846	Transcriptional regulator
FSC11_RS14950	COG1764	response to oxidative stress
FSC11_RS14955	COG2801	Transposase and inactivated derivatives
FSC11_RS14985	COG3657	addiction module killer protein
FSC11_RS14990	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC11_RS15000	COG2801	Transposase and inactivated derivatives
FSC11_RS15025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC11_RS15085	COG1373	ATPase (AAA superfamily
FSC11_RS15165	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC11_RS15190	COG4974	Belongs to the 'phage' integrase family
FSC11_RS15240	COG1683	Conserved Protein
FSC11_RS15275	COG1230	cation diffusion facilitator family transporter
FSC11_RS15290	COG0582	viral genome integration into host DNA
FSC11_RS15390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FSC11_RS15415	COG3451	type IV secretory pathway VirB4
FSC11_RS15550	COG2026	Addiction module toxin, RelE StbE family
FSC11_RS15565	COG3121	Chaperone
FSC11_RS15585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FSC11_RS15590	COG1335	isochorismatase
FSC11_RS15595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSC11_RS15620	COG2963	transposase activity
FSC11_RS15705	COG1192	Involved in chromosome partitioning
FSC11_RS15755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FSC11_RS15860	COG3657	addiction module killer protein
FSC11_RS15865	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC11_RS15875	COG0488	(ABC) transporter
FSC11_RS15980	COG3173	Aminoglycoside phosphotransferase
FSC11_RS16040	COG4115	mRNA cleavage