locus-tag	class	description
IC772_RS00010	COG0592	DNA-directed DNA polymerase activity
IC772_RS00020	COG0187	DNA topoisomerase II activity
IC772_RS00030	COG0586	Pfam SNARE associated Golgi protein
IC772_RS00035	COG0488	(ABC) transporter
IC772_RS00060	COG0596	Alpha beta hydrolase
IC772_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC772_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC772_RS00105	COG0625	glutathione transferase activity
IC772_RS00115	COG0733	neurotransmitter:sodium symporter activity
IC772_RS00155	COG2233	PERMEase
IC772_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS00205	COG2814	Major facilitator Superfamily
IC772_RS00210	COG0656	L-ascorbic acid biosynthetic process
IC772_RS00215	COG0583	DNA-binding transcription factor activity
IC772_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC772_RS00235	COG1064	alcohol dehydrogenase
IC772_RS00255	COG1194	a g-specific adenine glycosylase
IC772_RS00270	COG5487	UPF0391 membrane protein
IC772_RS00275	COG2983	Belongs to the UPF0260 family
IC772_RS00280	COG2133	pyrroloquinoline quinone binding
IC772_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC772_RS00290	COG2116	formate transmembrane transporter activity
IC772_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC772_RS00315	COG1335	isochorismatase
IC772_RS00320	COG0385	Bile acid
IC772_RS00325	COG0534	Mate efflux family protein
IC772_RS00330	COG1683	Conserved Protein
IC772_RS00345	COG0346	lactoylglutathione lyase activity
IC772_RS00350	COG0625	glutathione transferase activity
IC772_RS00360	COG1113	amino acid transport
IC772_RS00370	COG0523	cobalamin synthesis protein
IC772_RS00380	COG2188	Transcriptional regulator
IC772_RS00410	COG0010	Belongs to the arginase family
IC772_RS00420	COG0546	phosphoglycolate phosphatase activity
IC772_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC772_RS00430	COG1280	lysine exporter protein (LysE YggA)
IC772_RS00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC772_RS00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC772_RS00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC772_RS00565	COG0534	Mate efflux family protein
IC772_RS00570	COG0436	Aminotransferase
IC772_RS00575	COG2733	membrane
IC772_RS00590	COG2918	glutathione biosynthetic process
IC772_RS00625	COG3150	esterase
IC772_RS00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC772_RS00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC772_RS00660	COG2351	hydroxyisourate hydrolase activity
IC772_RS00695	COG3706	GGDEF domain
IC772_RS00710	COG1393	Belongs to the ArsC family
IC772_RS00715	COG0708	Exodeoxyribonuclease III
IC772_RS00765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC772_RS00775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC772_RS00790	COG4942	peptidase
IC772_RS00800	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC772_RS00810	COG2119	membrane
IC772_RS00815	COG4774	siderophore transport
IC772_RS00820	COG0426	domain, Protein
IC772_RS00820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC772_RS00845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC772_RS00865	COG1902	pentaerythritol trinitrate reductase activity
IC772_RS00870	COG1519	Transferase
IC772_RS00875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC772_RS00880	COG0668	transmembrane transport
IC772_RS00890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC772_RS00895	COG1335	isochorismatase
IC772_RS00900	COG1522	sequence-specific DNA binding
IC772_RS00925	COG2205	protein histidine kinase activity
IC772_RS00925	COG0784	Response regulator, receiver
IC772_RS00925	COG2198	Histidine kinase
IC772_RS00930	COG3162	membrane
IC772_RS00935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC772_RS00945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC772_RS00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IC772_RS00965	COG1309	transcriptional regulator
IC772_RS00985	COG0300	oxidoreductase activity
IC772_RS00995	COG0352	thiamine-phosphate diphosphorylase activity
IC772_RS00995	COG0351	phosphomethylpyrimidine kinase
IC772_RS00995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC772_RS01005	COG2814	Major facilitator Superfamily
IC772_RS01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC772_RS01040	COG1113	amino acid transport
IC772_RS01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC772_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS01065	COG1335	isochorismatase
IC772_RS01135	COG2814	Major facilitator Superfamily
IC772_RS01140	COG0583	DNA-binding transcription factor activity
IC772_RS01165	COG0667	Aldo Keto reductase
IC772_RS01195	COG1733	regulation of RNA biosynthetic process
IC772_RS01200	COG1733	regulation of RNA biosynthetic process
IC772_RS01215	COG1733	regulation of RNA biosynthetic process
IC772_RS01220	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC772_RS01240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IC772_RS01245	COG2207	Transcriptional regulator
IC772_RS01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC772_RS01315	COG2329	Antibiotic biosynthesis monooxygenase
IC772_RS01345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC772_RS01375	COG0427	acetyl-CoA hydrolase
IC772_RS01405	COG0659	secondary active sulfate transmembrane transporter activity
IC772_RS01410	COG4221	oxidoreductase activity
IC772_RS01420	COG0028	Belongs to the TPP enzyme family
IC772_RS01425	COG0488	(ABC) transporter
IC772_RS01605	COG0582	viral genome integration into host DNA
IC772_RS01625	COG0833	amino acid
IC772_RS01670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC772_RS01675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC772_RS01690	COG2226	methyltransferase
IC772_RS01740	COG0069	glutamate synthase activity
IC772_RS01740	COG0070	glutamate synthase
IC772_RS01740	COG0067	glutamate synthase
IC772_RS01745	COG0493	'glutamate synthase
IC772_RS01755	COG1704	LemA family
IC772_RS01760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC772_RS01770	COG4969	Belongs to the N-Me-Phe pilin family
IC772_RS01780	COG3307	-O-antigen
IC772_RS01800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC772_RS01815	COG0194	GDP metabolic process
IC772_RS01865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC772_RS01875	COG0335	large ribosomal subunit rRNA binding
IC772_RS01885	COG5380	lipid catabolic process
IC772_RS01890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC772_RS01910	COG5006	permease, DMT superfamily
IC772_RS01915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC772_RS01920	COG0277	FAD linked oxidase domain protein
IC772_RS01930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC772_RS01935	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC772_RS01955	COG1289	transmembrane transporter activity
IC772_RS01965	COG0628	permease
IC772_RS01970	COG1192	Involved in chromosome partitioning
IC772_RS02000	COG0833	amino acid
IC772_RS02005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC772_RS02010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC772_RS02020	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS02045	COG1404	Belongs to the peptidase S8 family
IC772_RS02060	COG0583	DNA-binding transcription factor activity
IC772_RS02065	COG1794	racemase activity, acting on amino acids and derivatives
IC772_RS02070	COG0583	DNA-binding transcription factor activity
IC772_RS02105	COG0752	glycyl-tRNA synthetase alpha subunit
IC772_RS02130	COG0517	IMP dehydrogenase activity
IC772_RS02135	COG1983	PspC domain protein
IC772_RS02145	COG1960	acyl-CoA dehydrogenase activity
IC772_RS02160	COG0408	coproporphyrinogen oxidase activity
IC772_RS02180	COG0513	Belongs to the DEAD box helicase family
IC772_RS02185	COG1127	ABC transporter
IC772_RS02190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC772_RS02200	COG2854	intermembrane phospholipid transfer
IC772_RS02210	COG0598	Magnesium transport protein CorA
IC772_RS02220	COG0494	nUDIX hydrolase
IC772_RS02225	COG1040	competence protein
IC772_RS02230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC772_RS02245	COG2937	Belongs to the GPAT DAPAT family
IC772_RS02250	COG1946	Acyl-CoA thioesterase
IC772_RS02255	COG1301	dicarboxylic acid transport
IC772_RS02270	COG1959	2 iron, 2 sulfur cluster binding
IC772_RS02275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC772_RS02275	COG1017	nitric oxide dioxygenase activity
IC772_RS02280	COG0433	COG0433 Predicted ATPase
IC772_RS02285	COG0626	cystathionine gamma-synthase activity
IC772_RS02300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC772_RS02305	COG0088	Forms part of the polypeptide exit tunnel
IC772_RS02440	COG1960	acyl-CoA dehydrogenase activity
IC772_RS02445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC772_RS02475	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC772_RS02480	COG0339	signal peptide processing
IC772_RS02485	COG0557	exoribonuclease II activity
IC772_RS02530	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC772_RS02535	COG2169	Transcriptional regulator
IC772_RS02545	COG1295	ribonuclease BN
IC772_RS02580	COG1702	phosphate starvation-inducible protein PhoH
IC772_RS02590	COG0739	heme binding
IC772_RS02590	COG0741	lytic transglycosylase activity
IC772_RS02590	COG1196	nuclear chromosome segregation
IC772_RS02620	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC772_RS02625	COG1183	phosphatidylcholine synthase activity
IC772_RS02675	COG1960	acyl-CoA dehydrogenase activity
IC772_RS02680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC772_RS02685	COG1309	transcriptional regulator
IC772_RS02700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC772_RS02705	COG1960	acyl-CoA dehydrogenase activity
IC772_RS02745	COG2969	positive regulation of protein catabolic process
IC772_RS02755	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC772_RS02760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC772_RS02765	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC772_RS02770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC772_RS02775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC772_RS02795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC772_RS02805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC772_RS02810	COG1408	metallophosphoesterase
IC772_RS02820	COG2199	diguanylate cyclase activity
IC772_RS02880	COG1607	acyl-coa hydrolase
IC772_RS02915	COG2350	Protein conserved in bacteria
IC772_RS02930	COG3781	membrane
IC772_RS02940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC772_RS02945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC772_RS02955	COG1862	Preprotein translocase
IC772_RS03010	COG2194	sulfuric ester hydrolase activity
IC772_RS03020	COG0726	polysaccharide deacetylase
IC772_RS03025	COG0463	Glycosyl transferase, family 2
IC772_RS03030	COG0438	transferase activity, transferring glycosyl groups
IC772_RS03070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC772_RS03105	COG1960	acyl-CoA dehydrogenase activity
IC772_RS03110	COG1960	acyl-CoA dehydrogenase activity
IC772_RS03120	COG2205	protein histidine kinase activity
IC772_RS03125	COG0745	RESPONSE REGULATOR receiver
IC772_RS03135	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC772_RS03155	COG2096	Adenosyltransferase
IC772_RS03210	COG0285	dihydrofolate synthase activity
IC772_RS03230	COG0450	alkyl hydroperoxide reductase
IC772_RS03245	COG0477	Major facilitator Superfamily
IC772_RS03250	COG1272	protein, Hemolysin III
IC772_RS03260	COG2153	protein acetylation
IC772_RS03280	COG0183	Belongs to the thiolase family
IC772_RS03290	COG2207	Transcriptional regulator
IC772_RS03310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC772_RS03325	COG0183	Belongs to the thiolase family
IC772_RS03335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC772_RS03335	COG2885	chlorophyll binding
IC772_RS03345	COG1690	Belongs to the RtcB family
IC772_RS03350	COG0833	amino acid
IC772_RS03360	COG2233	PERMEase
IC772_RS03365	COG1217	gtp-binding protein TYPA
IC772_RS03395	COG2094	Belongs to the DNA glycosylase MPG family
IC772_RS03400	COG4772	TonB-dependent receptor
IC772_RS03405	COG1902	pentaerythritol trinitrate reductase activity
IC772_RS03410	COG0679	Auxin Efflux Carrier
IC772_RS03420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC772_RS03425	COG0354	folic acid binding
IC772_RS03435	COG3189	MarR family transcriptional regulator
IC772_RS03440	COG2824	Alkylphosphonate utilization operon protein PhnA
IC772_RS03445	COG3422	double-strand break repair
IC772_RS03485	COG0840	transmembrane signaling receptor activity
IC772_RS03500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC772_RS03525	COG2832	Protein of unknown function (DUF454)
IC772_RS03530	COG1376	ErfK ybiS ycfS ynhG family protein
IC772_RS03580	COG1289	transmembrane transporter activity
IC772_RS03585	COG2814	Major facilitator Superfamily
IC772_RS03605	COG1115	amino acid carrier protein
IC772_RS03610	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC772_RS03615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC772_RS03620	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC772_RS03640	COG1132	(ABC) transporter
IC772_RS03665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC772_RS03675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC772_RS03680	COG1077	Cell shape determining protein MreB Mrl
IC772_RS03685	COG1792	Involved in formation and maintenance of cell shape
IC772_RS03690	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC772_RS03695	COG0424	maF-like protein
IC772_RS03700	COG1530	ribonuclease E activity
IC772_RS03710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC772_RS03730	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC772_RS03755	COG2207	Transcriptional regulator
IC772_RS03800	COG3046	protein related to deoxyribodipyrimidine photolyase
IC772_RS03805	COG2816	NAD+ diphosphatase activity
IC772_RS03815	COG2828	Protein conserved in bacteria
IC772_RS03820	COG0142	geranyltranstransferase activity
IC772_RS03825	COG2315	Protein conserved in bacteria
IC772_RS03840	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC772_RS03865	COG2194	sulfuric ester hydrolase activity
IC772_RS03870	COG0745	RESPONSE REGULATOR receiver
IC772_RS03875	COG0642	Histidine kinase
IC772_RS03885	COG0004	ammonium transporteR
IC772_RS03890	COG0583	DNA-binding transcription factor activity
IC772_RS03910	COG0525	valine-tRNA ligase activity
IC772_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS03930	COG0393	Putative heavy-metal-binding
IC772_RS03935	COG0393	Putative heavy-metal-binding
IC772_RS03940	COG1538	Outer membrane efflux protein
IC772_RS03950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS03955	COG0671	phosphoesterase, PA-phosphatase related
IC772_RS03985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC772_RS04000	COG1648	precorrin-2 dehydrogenase activity
IC772_RS04000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC772_RS04005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC772_RS04010	COG1733	regulation of RNA biosynthetic process
IC772_RS04020	COG0531	amino acid
IC772_RS04035	COG0321	lipoyl(octanoyl) transferase activity
IC772_RS04040	COG2921	Belongs to the UPF0250 family
IC772_RS04075	COG2009	succinate dehydrogenase
IC772_RS04080	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC772_RS04085	COG1053	succinate dehydrogenase
IC772_RS04090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC772_RS04115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC772_RS04135	COG2354	Protein conserved in bacteria
IC772_RS04140	COG2321	neutral zinc metallopeptidase
IC772_RS04160	COG2843	Capsule synthesis protein
IC772_RS04180	COG0589	response to stress
IC772_RS04200	COG0505	Belongs to the CarA family
IC772_RS04225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC772_RS04275	COG0477	Major facilitator Superfamily
IC772_RS04280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC772_RS04295	COG1597	lipid kinase activity
IC772_RS04360	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC772_RS04365	COG0210	DNA helicase
IC772_RS04385	COG1196	nuclear chromosome segregation
IC772_RS04400	COG0582	viral genome integration into host DNA
IC772_RS04410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC772_RS04415	COG0584	glycerophosphoryl diester phosphodiesterase
IC772_RS04435	COG0741	lytic transglycosylase activity
IC772_RS04455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC772_RS04460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC772_RS04475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS04495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC772_RS04530	COG3811	Belongs to the UPF0386 family
IC772_RS04560	COG1309	transcriptional regulator
IC772_RS04565	COG1902	pentaerythritol trinitrate reductase activity
IC772_RS04570	COG0596	Alpha beta hydrolase
IC772_RS04570	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC772_RS04575	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC772_RS04575	COG0596	Alpha beta hydrolase
IC772_RS04580	COG0596	Alpha beta hydrolase
IC772_RS04590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS04595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC772_RS04600	COG0778	Nitroreductase
IC772_RS04615	COG1929	Belongs to the glycerate kinase type-1 family
IC772_RS04620	COG0243	molybdopterin cofactor binding
IC772_RS04625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC772_RS04655	COG1115	amino acid carrier protein
IC772_RS04660	COG1113	amino acid transport
IC772_RS04670	COG0019	diaminopimelate decarboxylase activity
IC772_RS04680	COG1280	lysine exporter protein (LysE YggA)
IC772_RS04685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC772_RS04705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC772_RS04715	COG0463	Glycosyl transferase, family 2
IC772_RS04735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS04770	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC772_RS04775	COG1136	(ABC) transporter
IC772_RS04780	COG0658	competence protein
IC772_RS04780	COG2333	competence protein COMEC
IC772_RS04790	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC772_RS04790	COG0616	signal peptide processing
IC772_RS04795	COG0596	Alpha beta hydrolase
IC772_RS04800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC772_RS04810	COG0628	permease
IC772_RS04845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC772_RS04865	COG0823	Involved in the tonB-independent uptake of proteins
IC772_RS04885	COG0824	Thioesterase
IC772_RS04890	COG1473	amidohydrolase
IC772_RS04920	COG0047	phosphoribosylformylglycinamidine synthase activity
IC772_RS04920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC772_RS04930	COG2814	Major facilitator Superfamily
IC772_RS04950	COG1024	Enoyl-CoA hydratase
IC772_RS04955	COG1051	belongs to the nudix hydrolase family
IC772_RS04955	COG1056	cytidyltransferase-related domain
IC772_RS04970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC772_RS04985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC772_RS04990	COG0602	queuosine metabolic process
IC772_RS05000	COG4625	pathogenesis
IC772_RS05005	COG0583	DNA-binding transcription factor activity
IC772_RS05010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC772_RS05015	COG4208	sulfate ABC transporter
IC772_RS05020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC772_RS05030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC772_RS05035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC772_RS05040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC772_RS05060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC772_RS05075	COG0481	GTPase activity
IC772_RS05080	COG0681	Belongs to the peptidase S26 family
IC772_RS05095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC772_RS05105	COG1381	Involved in DNA repair and RecF pathway recombination
IC772_RS05110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC772_RS05120	COG4221	oxidoreductase activity
IC772_RS05165	COG3706	GGDEF domain
IC772_RS05170	COG0556	nucleotide-excision repair
IC772_RS05225	COG2070	2-Nitropropane dioxygenase
IC772_RS05255	COG1215	transferase activity, transferring glycosyl groups
IC772_RS05270	COG0415	Belongs to the DNA photolyase family
IC772_RS05285	COG1686	Belongs to the peptidase S11 family
IC772_RS05300	COG1187	pseudouridine synthase activity
IC772_RS05365	COG0477	Major facilitator Superfamily
IC772_RS05370	COG0583	DNA-binding transcription factor activity
IC772_RS05375	COG1823	symporter activity
IC772_RS05385	COG0612	Peptidase, M16
IC772_RS05410	COG0352	thiamine-phosphate diphosphorylase activity
IC772_RS05445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC772_RS05460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC772_RS05465	COG0076	glutamate decarboxylase activity
IC772_RS05475	COG1522	sequence-specific DNA binding
IC772_RS05480	COG3961	Belongs to the TPP enzyme family
IC772_RS05485	COG1113	amino acid transport
IC772_RS05490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC772_RS05495	COG0573	inorganic phosphate transmembrane transporter activity
IC772_RS05505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC772_RS05525	COG3647	Membrane
IC772_RS05550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC772_RS05555	COG1686	Belongs to the peptidase S11 family
IC772_RS05580	COG0583	DNA-binding transcription factor activity
IC772_RS05585	COG1067	ATP-dependent peptidase activity
IC772_RS05610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC772_RS05625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC772_RS05630	COG1966	Carbon starvation protein
IC772_RS05635	COG2879	small protein
IC772_RS05700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC772_RS05705	COG2423	ornithine cyclodeaminase activity
IC772_RS05715	COG2964	Protein conserved in bacteria
IC772_RS05725	COG1741	Belongs to the pirin family
IC772_RS05740	COG3739	integral membrane protein
IC772_RS05760	COG0302	gtp cyclohydrolase
IC772_RS05770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC772_RS05780	COG2840	Smr protein MutS2
IC772_RS05795	COG0512	Glutamine amidotransferase of anthranilate synthase
IC772_RS05810	COG1876	peptidase activity
IC772_RS05830	COG0174	glutamine synthetase
IC772_RS05840	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC772_RS05875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC772_RS05880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC772_RS05885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC772_RS05905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC772_RS05910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC772_RS05915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC772_RS05930	COG1960	acyl-CoA dehydrogenase activity
IC772_RS05935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC772_RS05940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC772_RS05950	COG2223	nitrite transmembrane transporter activity
IC772_RS05960	COG0024	Methionine aminopeptidase
IC772_RS05965	COG0052	Belongs to the universal ribosomal protein uS2 family
IC772_RS05980	COG2207	Transcriptional regulator
IC772_RS06005	COG2951	lytic endotransglycosylase activity
IC772_RS06010	COG0772	Belongs to the SEDS family
IC772_RS06025	COG0842	Transport permease protein
IC772_RS06030	COG1131	(ABC) transporter
IC772_RS06070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS06085	COG4215	(ABC) transporter
IC772_RS06090	COG4160	amino acid transport
IC772_RS06095	COG4598	ABC transporter
IC772_RS06105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC772_RS06110	COG0826	peptidase U32
IC772_RS06115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC772_RS06130	COG1720	tRNA m6t6A37 methyltransferase activity
IC772_RS06140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC772_RS06155	COG0642	Histidine kinase
IC772_RS06165	COG0494	nUDIX hydrolase
IC772_RS06175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC772_RS06180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC772_RS06185	COG3139	Protein of unknown function (DUF1315)
IC772_RS06190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC772_RS06195	COG1301	dicarboxylic acid transport
IC772_RS06200	COG1960	acyl-CoA dehydrogenase activity
IC772_RS06220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC772_RS06230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC772_RS06235	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC772_RS06255	COG1690	Belongs to the RtcB family
IC772_RS06260	COG1234	tRNA 3'-trailer cleavage
IC772_RS06265	COG4650	regulator
IC772_RS06290	COG2363	Small membrane protein
IC772_RS06310	COG0513	Belongs to the DEAD box helicase family
IC772_RS06320	COG0778	Nitroreductase
IC772_RS06380	COG1610	YqeY-like protein
IC772_RS06410	COG0515	serine threonine protein kinase
IC772_RS06410	COG2815	serine threonine protein kinase
IC772_RS06435	COG2831	hemolysin activation secretion protein
IC772_RS06440	COG3210	domain, Protein
IC772_RS06575	COG0786	glutamate:sodium symporter activity
IC772_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS06630	COG2169	Transcriptional regulator
IC772_RS06630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC772_RS06645	COG2985	domain, Protein
IC772_RS06670	COG2995	paraquat-inducible protein a
IC772_RS06675	COG3008	intermembrane lipid transfer
IC772_RS06675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC772_RS06685	COG2351	hydroxyisourate hydrolase activity
IC772_RS06700	COG5002	protein histidine kinase activity
IC772_RS06725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC772_RS06735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC772_RS06740	COG0642	Histidine kinase
IC772_RS06745	COG0745	RESPONSE REGULATOR receiver
IC772_RS06765	COG1794	racemase activity, acting on amino acids and derivatives
IC772_RS06795	COG1301	dicarboxylic acid transport
IC772_RS06810	COG2011	ABC-type metal ion transport system permease component
IC772_RS06815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC772_RS06820	COG1464	Belongs to the NlpA lipoprotein family
IC772_RS06825	COG0151	Belongs to the GarS family
IC772_RS06830	COG0138	bifunctional purine biosynthesis protein purh
IC772_RS06835	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC772_RS06865	COG2308	Evidence 4 Homologs of previously reported genes of
IC772_RS06875	COG1305	Transglutaminase-like
IC772_RS06885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC772_RS06890	COG0305	Participates in initiation and elongation during chromosome replication
IC772_RS06915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC772_RS06925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC772_RS06955	COG1649	PFAM Uncharacterised BCR, COG1649
IC772_RS06955	COG0726	polysaccharide deacetylase
IC772_RS06960	COG1215	transferase activity, transferring glycosyl groups
IC772_RS06965	COG3658	cytochrome
IC772_RS06975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC772_RS06995	COG2890	protein-(glutamine-N5) methyltransferase activity
IC772_RS07010	COG1960	acyl-CoA dehydrogenase activity
IC772_RS07015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC772_RS07020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC772_RS07035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IC772_RS07045	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC772_RS07050	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC772_RS07055	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC772_RS07060	COG2205	protein histidine kinase activity
IC772_RS07065	COG0745	RESPONSE REGULATOR receiver
IC772_RS07070	COG0174	glutamine synthetase
IC772_RS07090	COG0729	surface antigen
IC772_RS07120	COG0471	metal ion transport
IC772_RS07130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC772_RS07135	COG2814	Major facilitator Superfamily
IC772_RS07145	COG0583	DNA-binding transcription factor activity
IC772_RS07160	COG1187	pseudouridine synthase activity
IC772_RS07180	COG0802	atpase or kinase
IC772_RS07185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC772_RS07195	COG1923	regulation of RNA biosynthetic process
IC772_RS07200	COG0697	spore germination
IC772_RS07225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC772_RS07230	COG0519	Catalyzes the synthesis of GMP from XMP
IC772_RS07230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC772_RS07235	COG4302	ethanolamine ammonia-lyase activity
IC772_RS07240	COG4303	Ethanolamine ammonia lyase large subunit
IC772_RS07245	COG0531	amino acid
IC772_RS07265	COG1454	alcohol dehydrogenase
IC772_RS07270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC772_RS07280	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC772_RS07300	COG0308	aminopeptidase N
IC772_RS07335	COG0625	glutathione transferase activity
IC772_RS07350	COG1605	Chorismate mutase
IC772_RS07360	COG1280	lysine exporter protein (LysE YggA)
IC772_RS07365	COG1082	Xylose isomerase domain protein TIM barrel
IC772_RS07400	COG4264	IucA IucC family
IC772_RS07410	COG4264	IucA IucC family
IC772_RS07415	COG2423	ornithine cyclodeaminase activity
IC772_RS07420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC772_RS07430	COG0668	transmembrane transport
IC772_RS07475	COG0488	(ABC) transporter
IC772_RS07480	COG0589	response to stress
IC772_RS07505	COG3135	benzoate transporter
IC772_RS07510	COG1522	sequence-specific DNA binding
IC772_RS07520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC772_RS07525	COG0583	DNA-binding transcription factor activity
IC772_RS07535	COG0183	Belongs to the thiolase family
IC772_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS07545	COG2030	dehydratase
IC772_RS07550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC772_RS07575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC772_RS07585	COG0824	Thioesterase
IC772_RS07590	COG1454	alcohol dehydrogenase
IC772_RS07615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC772_RS07645	COG0069	glutamate synthase activity
IC772_RS07685	COG2814	Major facilitator Superfamily
IC772_RS07700	COG0511	ligase activity, forming carbon-carbon bonds
IC772_RS07720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC772_RS07720	COG1116	anion transmembrane transporter activity
IC772_RS07725	COG0745	RESPONSE REGULATOR receiver
IC772_RS07735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC772_RS07735	COG2146	nitrite reductase [NAD(P)H] activity
IC772_RS07740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC772_RS07745	COG0243	molybdopterin cofactor binding
IC772_RS07755	COG0243	molybdopterin cofactor binding
IC772_RS07760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC772_RS07775	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC772_RS07775	COG0315	cyclic pyranopterin monophosphate synthase activity
IC772_RS07780	COG0303	'Molybdopterin
IC772_RS07790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC772_RS07795	COG0697	spore germination
IC772_RS07815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC772_RS07820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC772_RS07875	COG2204	response regulator
IC772_RS07880	COG3852	Histidine kinase
IC772_RS07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC772_RS07905	COG0575	Belongs to the CDS family
IC772_RS07940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC772_RS07955	COG2137	regulation of response to DNA damage stimulus
IC772_RS07965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC772_RS07970	COG1011	Hydrolase
IC772_RS07985	COG1522	sequence-specific DNA binding
IC772_RS07995	COG1113	amino acid transport
IC772_RS08020	COG5001	Diguanylate cyclase
IC772_RS08020	COG3300	MHYT domain
IC772_RS08040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC772_RS08040	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC772_RS08040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC772_RS08045	COG1105	Belongs to the carbohydrate kinase PfkB family
IC772_RS08050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC772_RS08050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC772_RS08080	COG0024	Methionine aminopeptidase
IC772_RS08085	COG0583	DNA-binding transcription factor activity
IC772_RS08095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC772_RS08100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC772_RS08105	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC772_RS08130	COG0552	protein localization to endoplasmic reticulum
IC772_RS08140	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IC772_RS08155	COG4890	Cyd operon protein YbgT
IC772_RS08160	COG1294	oxidase, subunit
IC772_RS08175	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC772_RS08185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC772_RS08190	COG4774	siderophore transport
IC772_RS08205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC772_RS08210	COG0569	domain protein
IC772_RS08215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC772_RS08245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC772_RS08250	COG0542	response to heat
IC772_RS08275	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC772_RS08275	COG1902	pentaerythritol trinitrate reductase activity
IC772_RS08315	COG0148	phosphopyruvate hydratase activity
IC772_RS08320	COG2323	membrane
IC772_RS08330	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC772_RS08340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC772_RS08345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC772_RS08350	COG0183	Belongs to the thiolase family
IC772_RS08355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC772_RS08360	COG0596	Alpha beta hydrolase
IC772_RS08365	COG2271	Major facilitator Superfamily
IC772_RS08370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC772_RS08375	COG3485	protocatechuate 3,4-dioxygenase
IC772_RS08380	COG3485	protocatechuate 3,4-dioxygenase
IC772_RS08385	COG0710	3-dehydroquinate dehydratase activity
IC772_RS08390	COG3420	alginic acid biosynthetic process
IC772_RS08395	COG3659	wide pore channel activity
IC772_RS08400	COG4993	Dehydrogenase
IC772_RS08410	COG2391	methyltransferase activity
IC772_RS08425	COG1414	Transcriptional regulator
IC772_RS08430	COG0583	DNA-binding transcription factor activity
IC772_RS08435	COG1960	acyl-CoA dehydrogenase activity
IC772_RS08460	COG2814	Major facilitator Superfamily
IC772_RS08470	COG0154	amidase activity
IC772_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS08510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC772_RS08520	COG3733	amine oxidase
IC772_RS08530	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS08535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC772_RS08540	COG0183	Belongs to the thiolase family
IC772_RS08545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC772_RS08550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC772_RS08560	COG4829	muconolactone delta-isomerase
IC772_RS08565	COG4948	Mandelate Racemase Muconate Lactonizing
IC772_RS08570	COG0583	DNA-binding transcription factor activity
IC772_RS08600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC772_RS08625	COG1309	transcriptional regulator
IC772_RS08650	COG4689	acetoacetate decarboxylase
IC772_RS08660	COG1902	pentaerythritol trinitrate reductase activity
IC772_RS08670	COG2831	hemolysin activation secretion protein
IC772_RS08675	COG3210	domain, Protein
IC772_RS08710	COG2188	Transcriptional regulator
IC772_RS08725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC772_RS08740	COG2271	Major facilitator Superfamily
IC772_RS08750	COG1566	PFAM secretion protein HlyD family protein
IC772_RS08780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC772_RS08785	COG1120	ATPase activity
IC772_RS08805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC772_RS08945	COG0583	DNA-binding transcription factor activity
IC772_RS08960	COG2706	6-phosphogluconolactonase activity
IC772_RS08975	COG2851	Citrate transporter
IC772_RS09035	COG3539	Fimbrial protein
IC772_RS09060	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC772_RS09070	COG0753	catalase activity
IC772_RS09080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC772_RS09085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC772_RS09095	COG2205	protein histidine kinase activity
IC772_RS09100	COG0745	RESPONSE REGULATOR receiver
IC772_RS09105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS09110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC772_RS09170	COG4771	TonB-dependent receptor
IC772_RS09180	COG3433	isochorismatase activity
IC772_RS09180	COG1535	isochorismatase
IC772_RS09185	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC772_RS09190	COG1169	isochorismate synthase
IC772_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS09205	COG3251	PFAM MbtH domain protein
IC772_RS09210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC772_RS09235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC772_RS09240	COG4149	molybdate abc transporter
IC772_RS09245	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC772_RS09255	COG4638	Rieske (2fe-2S)
IC772_RS09260	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC772_RS09265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC772_RS09265	COG0543	2 iron, 2 sulfur cluster binding
IC772_RS09280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC772_RS09290	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS09310	COG2207	Transcriptional regulator
IC772_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS09320	COG2610	gluconate transmembrane transporter activity
IC772_RS09325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC772_RS09370	COG0583	DNA-binding transcription factor activity
IC772_RS09390	COG0183	Belongs to the thiolase family
IC772_RS09395	COG0583	DNA-binding transcription factor activity
IC772_RS09400	COG0583	DNA-binding transcription factor activity
IC772_RS09415	COG1027	Aspartate ammonia-lyase
IC772_RS09425	COG0477	Major facilitator Superfamily
IC772_RS09435	COG2207	Transcriptional regulator
IC772_RS09435	COG1609	Transcriptional regulator
IC772_RS09450	COG0730	response to heat
IC772_RS09460	COG3453	Protein conserved in bacteria
IC772_RS09460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC772_RS09470	COG3781	membrane
IC772_RS09475	COG1063	alcohol dehydrogenase
IC772_RS09485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC772_RS09490	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC772_RS09495	COG0022	dehydrogenase e1 component
IC772_RS09500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC772_RS09505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC772_RS09520	COG3706	GGDEF domain
IC772_RS09535	COG0133	tryptophan synthase activity
IC772_RS09545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC772_RS09580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC772_RS09605	COG2226	methyltransferase
IC772_RS09655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC772_RS09660	COG4773	Receptor
IC772_RS09680	COG0730	response to heat
IC772_RS09685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC772_RS09700	COG0406	alpha-ribazole phosphatase activity
IC772_RS09705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC772_RS09725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC772_RS09740	COG1960	acyl-CoA dehydrogenase activity
IC772_RS09745	COG1960	acyl-CoA dehydrogenase activity
IC772_RS09750	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC772_RS09755	COG2207	Transcriptional regulator
IC772_RS09760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC772_RS09765	COG0776	regulation of translation
IC772_RS09790	COG0822	iron-sulfur transferase activity
IC772_RS09795	COG0316	Belongs to the HesB IscA family
IC772_RS09825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC772_RS09845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC772_RS09850	COG0702	epimerase
IC772_RS09880	COG4172	Belongs to the ABC transporter superfamily
IC772_RS09885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC772_RS09890	COG0601	transmembrane transport
IC772_RS09915	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC772_RS09940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC772_RS09945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC772_RS09960	COG2431	L-lysine efflux transmembrane transporter activity
IC772_RS09975	COG0776	regulation of translation
IC772_RS10040	COG0084	hydrolase, TatD family'
IC772_RS10060	COG1663	tetraacyldisaccharide 4'-kinase activity
IC772_RS10065	COG1132	(ABC) transporter
IC772_RS10075	COG0811	peptide transport
IC772_RS10080	COG1475	DNA binding
IC772_RS10085	COG1192	Involved in chromosome partitioning
IC772_RS10095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC772_RS10135	COG0424	maF-like protein
IC772_RS10140	COG2850	peptidyl-arginine hydroxylation
IC772_RS10150	COG0640	Transcriptional regulator
IC772_RS10160	COG3619	membrane
IC772_RS10165	COG3122	Protein conserved in bacteria
IC772_RS10170	COG1132	(ABC) transporter
IC772_RS10190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC772_RS10195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC772_RS10205	COG0506	proline dehydrogenase activity
IC772_RS10205	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC772_RS10205	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC772_RS10210	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC772_RS10225	COG3698	Phosphodiester glycosidase
IC772_RS10235	COG2353	YceI-like domain
IC772_RS10250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC772_RS10290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC772_RS10290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC772_RS10330	COG0697	spore germination
IC772_RS10340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC772_RS10350	COG0583	DNA-binding transcription factor activity
IC772_RS10370	COG2197	response regulator
IC772_RS10395	COG1522	sequence-specific DNA binding
IC772_RS10405	COG1126	abc transporter atp-binding protein
IC772_RS10410	COG0765	amino acid transport
IC772_RS10415	COG0765	amino acid transport
IC772_RS10445	COG1464	Belongs to the NlpA lipoprotein family
IC772_RS10450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC772_RS10455	COG2011	ABC-type metal ion transport system permease component
IC772_RS10460	COG0012	GTP binding
IC772_RS10485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC772_RS10525	COG0386	Belongs to the glutathione peroxidase family
IC772_RS10535	COG0436	Aminotransferase
IC772_RS10540	COG1301	dicarboxylic acid transport
IC772_RS10575	COG3634	alkyl hydroperoxide reductase activity
IC772_RS10590	COG0583	DNA-binding transcription factor activity
IC772_RS10595	COG0431	NADPH-dependent FMN reductase
IC772_RS10600	COG0798	PFAM Bile acid sodium symporter
IC772_RS10605	COG0640	Transcriptional regulator
IC772_RS10620	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IC772_RS10630	COG0583	DNA-binding transcription factor activity
IC772_RS10640	COG1953	Uracil, thiamine, allantoin
IC772_RS10650	COG2175	clavaminate synthase activity
IC772_RS10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC772_RS10660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC772_RS10665	COG4521	taurine ABC transporter
IC772_RS10675	COG0477	Major facilitator Superfamily
IC772_RS10695	COG1271	oxidase subunit
IC772_RS10700	COG1294	oxidase, subunit
IC772_RS10710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC772_RS10730	COG1346	cytolysis
IC772_RS10740	COG0583	DNA-binding transcription factor activity
IC772_RS10745	COG0625	glutathione transferase activity
IC772_RS10750	COG0625	glutathione transferase activity
IC772_RS10770	COG0583	DNA-binding transcription factor activity
IC772_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS10785	COG1045	serine acetyltransferase
IC772_RS10790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC772_RS10795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC772_RS10800	COG1280	lysine exporter protein (LysE YggA)
IC772_RS10805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IC772_RS10825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC772_RS10840	COG0765	amino acid transport
IC772_RS10860	COG0784	Response regulator, receiver
IC772_RS10860	COG2205	protein histidine kinase activity
IC772_RS10880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC772_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS10940	COG0583	DNA-binding transcription factor activity
IC772_RS10950	COG2814	Major facilitator Superfamily
IC772_RS10965	COG0318	PFAM AMP-dependent synthetase and ligase
IC772_RS10970	COG1309	transcriptional regulator
IC772_RS10975	COG1960	acyl-CoA dehydrogenase activity
IC772_RS10980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC772_RS10985	COG1024	Enoyl-CoA hydratase
IC772_RS10990	COG4770	biotin carboxylase activity
IC772_RS11000	COG0583	DNA-binding transcription factor activity
IC772_RS11015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC772_RS11020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC772_RS11040	COG1840	ABC-type Fe3 transport system, periplasmic component
IC772_RS11055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC772_RS11060	COG1414	Transcriptional regulator
IC772_RS11070	COG0583	DNA-binding transcription factor activity
IC772_RS11075	COG3038	cytochrome b561
IC772_RS11080	COG0753	catalase activity
IC772_RS11085	COG0531	amino acid
IC772_RS11090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC772_RS11105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC772_RS11110	COG1309	transcriptional regulator
IC772_RS11135	COG0406	alpha-ribazole phosphatase activity
IC772_RS11145	COG2050	protein possibly involved in aromatic compounds catabolism
IC772_RS11155	COG3327	negative regulation of DNA-templated transcription, initiation
IC772_RS11160	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC772_RS11165	COG0183	Belongs to the thiolase family
IC772_RS11170	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC772_RS11175	COG1024	Enoyl-CoA hydratase
IC772_RS11180	COG1024	Enoyl-CoA hydratase
IC772_RS11185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC772_RS11190	COG2151	metal-sulfur cluster biosynthetic enzyme
IC772_RS11195	COG3396	Phenylacetate-CoA oxygenase
IC772_RS11200	COG3460	Phenylacetate-CoA oxygenase
IC772_RS11205	COG3396	Phenylacetate-CoA oxygenase
IC772_RS11210	COG2030	dehydratase
IC772_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS11215	COG1760	l-serine dehydratase
IC772_RS11230	COG0789	Transcriptional regulator
IC772_RS11240	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC772_RS11245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC772_RS11260	COG2807	transmembrane transport
IC772_RS11265	COG0590	tRNA wobble adenosine to inosine editing
IC772_RS11370	COG0477	Major facilitator Superfamily
IC772_RS11385	COG1116	anion transmembrane transporter activity
IC772_RS11390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC772_RS11400	COG0864	Transcriptional regulator
IC772_RS11415	COG1733	regulation of RNA biosynthetic process
IC772_RS11420	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC772_RS11425	COG0439	Biotin carboxylase
IC772_RS11480	COG0038	chloride channel
IC772_RS11485	COG4770	biotin carboxylase activity
IC772_RS11505	COG1914	H( )-stimulated, divalent metal cation uptake system
IC772_RS11510	COG0583	DNA-binding transcription factor activity
IC772_RS11520	COG1595	DNA-templated transcription, initiation
IC772_RS11530	COG3220	belongs to the UPF0276 family
IC772_RS11560	COG2076	Multidrug Resistance protein
IC772_RS11575	COG3713	MltA-interacting MipA family protein
IC772_RS11580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC772_RS11660	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC772_RS11680	COG1309	transcriptional regulator
IC772_RS11685	COG1278	Cold shock
IC772_RS11695	COG0626	cystathionine gamma-synthase activity
IC772_RS11700	COG1522	sequence-specific DNA binding
IC772_RS11725	COG2814	Major facilitator Superfamily
IC772_RS11740	COG0402	S-adenosylhomocysteine deaminase activity
IC772_RS11745	COG0583	DNA-binding transcription factor activity
IC772_RS11755	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IC772_RS11785	COG0653	protein targeting
IC772_RS11790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS11825	COG1271	oxidase subunit
IC772_RS11830	COG1294	oxidase, subunit
IC772_RS11840	COG1469	GTP cyclohydrolase I activity
IC772_RS11965	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC772_RS11975	COG4122	O-methyltransferase activity
IC772_RS12005	COG1538	Outer membrane efflux protein
IC772_RS12010	COG1137	ATPase activity
IC772_RS12015	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC772_RS12025	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC772_RS12030	COG0517	IMP dehydrogenase activity
IC772_RS12030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC772_RS12060	COG0667	Aldo Keto reductase
IC772_RS12070	COG2814	Major facilitator Superfamily
IC772_RS12100	COG1278	Cold shock
IC772_RS12105	COG1280	lysine exporter protein (LysE YggA)
IC772_RS12135	COG1570	exodeoxyribonuclease VII activity
IC772_RS12165	COG3791	Glutathione-dependent formaldehyde-activating
IC772_RS12220	COG2871	sodium ion transport
IC772_RS12230	COG0583	DNA-binding transcription factor activity
IC772_RS12240	COG4638	Rieske (2fe-2S)
IC772_RS12245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC772_RS12250	COG0543	2 iron, 2 sulfur cluster binding
IC772_RS12250	COG0633	Ferredoxin
IC772_RS12255	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS12260	COG3135	benzoate transporter
IC772_RS12265	COG2814	Major facilitator Superfamily
IC772_RS12280	COG1643	Atp-dependent helicase
IC772_RS12295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC772_RS12305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IC772_RS12315	COG3634	alkyl hydroperoxide reductase activity
IC772_RS12335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC772_RS12340	COG0625	glutathione transferase activity
IC772_RS12385	COG0542	response to heat
IC772_RS12405	COG1765	OsmC-like protein
IC772_RS12415	COG0667	Aldo Keto reductase
IC772_RS12430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC772_RS12440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC772_RS12450	COG0582	viral genome integration into host DNA
IC772_RS12580	COG1598	PFAM Uncharacterised protein family UPF0150
IC772_RS12670	COG5410	chromosome segregation
IC772_RS12820	COG0527	aspartate kinase activity
IC772_RS12830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC772_RS12840	COG3038	cytochrome b561
IC772_RS12845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC772_RS12850	COG2252	PERMEase
IC772_RS12860	COG2072	flavoprotein involved in K transport
IC772_RS12875	COG1741	Belongs to the pirin family
IC772_RS12880	COG1309	transcriptional regulator
IC772_RS12895	COG2072	flavoprotein involved in K transport
IC772_RS12900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC772_RS12930	COG1944	ATP diphosphatase activity
IC772_RS12950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC772_RS12965	COG2814	Major facilitator Superfamily
IC772_RS12970	COG1024	Enoyl-CoA hydratase
IC772_RS12975	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS12985	COG1960	acyl-CoA dehydrogenase activity
IC772_RS13010	COG0697	spore germination
IC772_RS13025	COG1113	amino acid transport
IC772_RS13045	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS13065	COG0531	amino acid
IC772_RS13075	COG1113	amino acid transport
IC772_RS13110	COG1846	Transcriptional regulator
IC772_RS13165	COG4269	membrane
IC772_RS13185	COG0583	DNA-binding transcription factor activity
IC772_RS13195	COG0251	oxidation-reduction process
IC772_RS13270	COG5383	Protein conserved in bacteria
IC772_RS13275	COG0644	oxidoreductase
IC772_RS13275	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC772_RS13280	COG0277	FAD linked oxidase domain protein
IC772_RS13285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC772_RS13285	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IC772_RS13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC772_RS13295	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS13300	COG4638	Rieske (2fe-2S)
IC772_RS13305	COG2271	Major facilitator Superfamily
IC772_RS13345	COG1201	RNA secondary structure unwinding
IC772_RS13430	COG1902	pentaerythritol trinitrate reductase activity
IC772_RS13430	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC772_RS13450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC772_RS13480	COG4172	Belongs to the ABC transporter superfamily
IC772_RS13485	COG4239	(ABC) transporter, permease
IC772_RS13490	COG4174	ABC transporter (Permease)
IC772_RS13495	COG4166	transmembrane transport
IC772_RS13500	COG1388	LysM domain
IC772_RS13500	COG0741	lytic transglycosylase activity
IC772_RS13500	COG0741	lytic transglycosylase activity
IC772_RS13500	COG1388	LysM domain
IC772_RS13545	COG0583	DNA-binding transcription factor activity
IC772_RS13550	COG1279	arginine transmembrane transporter activity
IC772_RS13570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC772_RS13575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC772_RS13580	COG0006	proline dipeptidase activity
IC772_RS13615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC772_RS13660	COG3384	dioxygenase
IC772_RS13670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC772_RS13675	COG2878	Part of a membrane complex involved in electron transport
IC772_RS13680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC772_RS13705	COG0768	penicillin binding
IC772_RS13710	COG0742	ribosomal rna small subunit methyltransferase
IC772_RS13730	COG0830	nickel cation binding
IC772_RS13740	COG0804	urea catabolic process
IC772_RS13780	COG1253	flavin adenine dinucleotide binding
IC772_RS13785	COG2851	Citrate transporter
IC772_RS13835	COG1773	rubredoxin
IC772_RS13840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC772_RS13850	COG0583	DNA-binding transcription factor activity
IC772_RS13880	COG4181	ATPase activity
IC772_RS13925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC772_RS13945	COG0306	phosphate transporter
IC772_RS13975	COG2223	nitrite transmembrane transporter activity
IC772_RS13980	COG2207	Transcriptional regulator
IC772_RS13985	COG2066	Belongs to the glutaminase family
IC772_RS13990	COG0242	peptide deformylase activity
IC772_RS13995	COG0477	Major facilitator Superfamily
IC772_RS14005	COG0028	Belongs to the TPP enzyme family
IC772_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS14025	COG2267	carboxylic ester hydrolase activity
IC772_RS14035	COG2271	Major facilitator Superfamily
IC772_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS14070	COG1414	Transcriptional regulator
IC772_RS14100	COG1024	Enoyl-CoA hydratase
IC772_RS14110	COG1215	transferase activity, transferring glycosyl groups
IC772_RS14115	COG0726	polysaccharide deacetylase
IC772_RS14115	COG1649	PFAM Uncharacterised BCR, COG1649
IC772_RS14125	COG4681	YaeQ
IC772_RS14135	COG0523	cobalamin synthesis protein
IC772_RS14145	COG1607	acyl-coa hydrolase
IC772_RS14155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC772_RS14160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC772_RS14165	COG1309	transcriptional regulator
IC772_RS14190	COG2040	homocysteine
IC772_RS14195	COG0531	amino acid
IC772_RS14225	COG0477	Major facilitator Superfamily
IC772_RS14235	COG1404	Belongs to the peptidase S8 family
IC772_RS14320	COG0405	Gamma-glutamyltransferase
IC772_RS14325	COG2814	Major facilitator Superfamily
IC772_RS14335	COG2050	protein possibly involved in aromatic compounds catabolism
IC772_RS14350	COG1090	epimerase
IC772_RS14370	COG0420	3'-5' exonuclease activity
IC772_RS14380	COG1968	undecaprenyl-diphosphatase activity
IC772_RS14400	COG0735	belongs to the Fur family
IC772_RS14405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC772_RS14410	COG2914	Belongs to the UPF0125 (RnfH) family
IC772_RS14425	COG0121	glutamine amidotransferase
IC772_RS14440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC772_RS14450	COG0210	DNA helicase
IC772_RS14455	COG2885	chlorophyll binding
IC772_RS14460	COG0204	Acyl-transferase
IC772_RS14475	COG2894	cell division
IC772_RS14490	COG1280	lysine exporter protein (LysE YggA)
IC772_RS14495	COG1674	ftsk spoiiie
IC772_RS14500	COG0492	ferredoxin-NADP+ reductase activity
IC772_RS14505	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC772_RS14515	COG0456	acetyltransferase
IC772_RS14535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC772_RS14545	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC772_RS14560	COG1981	membrane
IC772_RS14570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC772_RS14570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC772_RS14590	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS14595	COG4638	Rieske (2fe-2S)
IC772_RS14600	COG0657	acetylesterase activity
IC772_RS14610	COG0473	3-isopropylmalate dehydrogenase activity
IC772_RS14615	COG0583	DNA-binding transcription factor activity
IC772_RS14635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC772_RS14660	COG0564	pseudouridine synthase activity
IC772_RS14670	COG0358	DNA primase activity
IC772_RS14685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC772_RS14715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC772_RS14745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC772_RS14755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC772_RS14755	COG0352	thiamine-phosphate diphosphorylase activity
IC772_RS14755	COG0351	phosphomethylpyrimidine kinase
IC772_RS14760	COG1652	LysM domain
IC772_RS14785	COG1399	metal-binding, possibly nucleic acid-binding protein
IC772_RS14790	COG3101	peptidyl-lysine hydroxylation
IC772_RS14795	COG0009	L-threonylcarbamoyladenylate synthase
IC772_RS14800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC772_RS14805	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC772_RS14820	COG4106	trans-aconitate 2-methyltransferase activity
IC772_RS14835	COG0596	Alpha beta hydrolase
IC772_RS14835	COG2226	methyltransferase
IC772_RS14835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC772_RS14840	COG1877	trehalose-phosphatase activity
IC772_RS14845	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC772_RS14850	COG2223	nitrite transmembrane transporter activity
IC772_RS14870	COG1196	nuclear chromosome segregation
IC772_RS14880	COG0730	response to heat
IC772_RS14895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC772_RS14905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC772_RS14950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC772_RS14955	COG0489	protein tyrosine kinase activity
IC772_RS14965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC772_RS14965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC772_RS15000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC772_RS15005	COG2081	HI0933 family
IC772_RS15015	COG0668	transmembrane transport
IC772_RS15035	COG0583	DNA-binding transcription factor activity
IC772_RS15060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC772_RS15065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC772_RS15080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC772_RS15095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC772_RS15120	COG3706	GGDEF domain
IC772_RS15135	COG0745	RESPONSE REGULATOR receiver
IC772_RS15155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC772_RS15260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC772_RS15265	COG0583	DNA-binding transcription factor activity
IC772_RS15270	COG0604	alcohol dehydrogenase
IC772_RS15275	COG1309	transcriptional regulator
IC772_RS15285	COG0384	phenazine biosynthesis protein PhzF
IC772_RS15375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC772_RS15390	COG0583	DNA-binding transcription factor activity
IC772_RS15410	COG0583	DNA-binding transcription factor activity
IC772_RS15425	COG0583	DNA-binding transcription factor activity
IC772_RS15430	COG1053	succinate dehydrogenase
IC772_RS15445	COG1309	transcriptional regulator
IC772_RS15455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC772_RS15460	COG2814	Major facilitator Superfamily
IC772_RS15465	COG1960	acyl-CoA dehydrogenase activity
IC772_RS15470	COG0583	DNA-binding transcription factor activity
IC772_RS15475	COG1063	alcohol dehydrogenase
IC772_RS15510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC772_RS15515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC772_RS15535	COG2132	Multicopper oxidase
IC772_RS15545	COG0561	phosphatase activity
IC772_RS15550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC772_RS15560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC772_RS15575	COG1214	PFAM Peptidase M22, glycoprotease
IC772_RS15625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC772_RS15635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC772_RS15640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC772_RS15645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC772_RS15705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC772_RS15715	COG1846	Transcriptional regulator
IC772_RS15720	COG1764	response to oxidative stress
IC772_RS15745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IC772_RS15745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IC772_RS15760	COG0037	tRNA processing
IC772_RS15770	COG0248	Ppx GppA phosphatase
IC772_RS15800	COG0072	phenylalanine-tRNA ligase activity
IC772_RS15830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC772_RS15840	COG1238	metal cluster binding
IC772_RS15845	COG0625	glutathione transferase activity
IC772_RS15860	COG0318	PFAM AMP-dependent synthetase and ligase
IC772_RS15865	COG3028	Belongs to the UPF0307 family
IC772_RS15890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC772_RS15895	COG0617	tRNA 3'-terminal CCA addition
IC772_RS15900	COG1555	photosystem II stabilization
IC772_RS15905	COG3956	TIGRFAM MazG family protein
IC772_RS15935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC772_RS15955	COG0784	Response regulator, receiver
IC772_RS15955	COG5002	protein histidine kinase activity
IC772_RS15955	COG2205	protein histidine kinase activity
IC772_RS15960	COG1024	Enoyl-CoA hydratase
IC772_RS15965	COG2084	Dehydrogenase
IC772_RS15970	COG3622	Belongs to the hyi family
IC772_RS16000	COG0697	spore germination
IC772_RS16010	COG2814	Major facilitator Superfamily
IC772_RS16015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC772_RS16025	COG0583	DNA-binding transcription factor activity
IC772_RS16035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC772_RS16050	COG0084	hydrolase, TatD family'
IC772_RS16065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC772_RS16090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC772_RS16095	COG0440	acetolactate synthase activity
IC772_RS16100	COG0028	Belongs to the TPP enzyme family
IC772_RS16125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC772_RS16130	COG0577	efflux transmembrane transporter activity
IC772_RS16130	COG1136	(ABC) transporter
IC772_RS16135	COG1538	Outer membrane efflux protein
IC772_RS16150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC772_RS16155	COG1162	GTPase activity
IC772_RS16165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC772_RS16185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC772_RS16190	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS16240	COG1216	Glycosyl transferase, family 2
IC772_RS16255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC772_RS16300	COG1426	Protein conserved in bacteria
IC772_RS16335	COG0793	Belongs to the peptidase S41A family
IC772_RS16350	COG2267	carboxylic ester hydrolase activity
IC772_RS16360	COG1012	belongs to the aldehyde dehydrogenase family
IC772_RS16365	COG3265	gluconokinase activity
IC772_RS16375	COG0800	Aldolase
IC772_RS16385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC772_RS16390	COG0857	belongs to the CobB CobQ family
IC772_RS16390	COG0280	phosphate acetyltransferase
IC772_RS16395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC772_RS16395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC772_RS16415	COG0740	serine-type endopeptidase activity
IC772_RS16425	COG4774	siderophore transport
IC772_RS16435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC772_RS16445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC772_RS16445	COG2813	Specifically methylates the guanine in position
IC772_RS16540	COG0788	formyltetrahydrofolate deformylase activity
IC772_RS16585	COG0724	RNA recognition motif
IC772_RS16590	COG0210	DNA helicase
IC772_RS16615	COG1733	regulation of RNA biosynthetic process
IC772_RS16625	COG2900	Belongs to the SlyX family
IC772_RS16630	COG0488	(ABC) transporter
IC772_RS16640	COG1280	lysine exporter protein (LysE YggA)
IC772_RS16645	COG1560	Kdo2-lipid A biosynthetic process
IC772_RS16655	COG1301	dicarboxylic acid transport
IC772_RS16710	COG0473	3-isopropylmalate dehydrogenase activity
IC772_RS16735	COG0583	DNA-binding transcription factor activity
IC772_RS16780	COG0583	DNA-binding transcription factor activity
IC772_RS16790	COG0625	glutathione transferase activity
IC772_RS16795	COG2378	regulation of single-species biofilm formation
IC772_RS16810	COG1530	ribonuclease E activity
IC772_RS16815	COG0318	PFAM AMP-dependent synthetase and ligase
IC772_RS16830	COG0583	DNA-binding transcription factor activity
IC772_RS16835	COG4221	oxidoreductase activity
IC772_RS16840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC772_RS16850	COG0534	Mate efflux family protein
IC772_RS16865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC772_RS16890	COG0493	'glutamate synthase
IC772_RS16890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC772_RS16900	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC772_RS16905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC772_RS16920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC772_RS16930	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC772_RS16930	COG0644	oxidoreductase
IC772_RS16945	COG4535	Mg2 and Co2 transporter CorC
IC772_RS16955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC772_RS16980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC772_RS16985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC772_RS16985	COG0475	glutathione-regulated potassium exporter activity
IC772_RS16990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC772_RS17000	COG0484	heat shock protein binding
IC772_RS17005	COG0789	Transcriptional regulator
IC772_RS17010	COG0598	Magnesium transport protein CorA
IC772_RS17015	COG1185	polyribonucleotide nucleotidyltransferase activity
IC772_RS17025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC772_RS17030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC772_RS17035	COG1074	ATP-dependent DNA helicase activity
IC772_RS17040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC772_RS17065	COG2226	methyltransferase
IC772_RS17085	COG1279	arginine transmembrane transporter activity
IC772_RS17095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC772_RS17110	COG2111	Na H antiporter
IC772_RS17110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC772_RS17115	COG1006	Multisubunit Na H antiporter MnhC subunit
IC772_RS17120	COG0651	ATP synthesis coupled electron transport
IC772_RS17125	COG1863	multisubunit Na H antiporter MnhE subunit
IC772_RS17130	COG2212	antiporter activity
IC772_RS17135	COG1320	monovalent cation:proton antiporter activity
IC772_RS17140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC772_RS17150	COG0195	Participates in both transcription termination and antitermination
IC772_RS17200	COG0237	dephospho-CoA kinase activity
IC772_RS17210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC772_RS17220	COG0497	DNA recombination
IC772_RS17230	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC772_RS17245	COG1289	transmembrane transporter activity
IC772_RS17260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC772_RS17325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC772_RS17340	COG0326	Molecular chaperone. Has ATPase activity
IC772_RS17355	COG2056	Na+-H+ antiporter family
IC772_RS17360	COG0596	Alpha beta hydrolase
IC772_RS17455	COG0546	phosphoglycolate phosphatase activity
IC772_RS17460	COG1716	ATPase activity
IC772_RS17505	COG0181	hydroxymethylbilane synthase activity
IC772_RS17515	COG3275	phosphorelay sensor kinase activity
IC772_RS17535	COG1538	Outer membrane efflux protein
IC772_RS17540	COG0697	spore germination
IC772_RS17560	COG0494	nUDIX hydrolase
IC772_RS17570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC772_RS17575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC772_RS17580	COG0772	Belongs to the SEDS family
IC772_RS17605	COG4974	Belongs to the 'phage' integrase family
IC772_RS17610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC772_RS17620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC772_RS17630	COG2197	response regulator
IC772_RS17645	COG0793	Belongs to the peptidase S41A family
IC772_RS17650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC772_RS17655	COG0795	lipopolysaccharide-transporting ATPase activity
IC772_RS17660	COG0795	lipopolysaccharide-transporting ATPase activity
IC772_RS17695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC772_RS17695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC772_RS17705	COG0004	ammonium transporteR
IC772_RS17710	COG0347	Belongs to the P(II) protein family
IC772_RS17720	COG0606	chelatase, subunit chli
IC772_RS17725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC772_RS17730	COG0235	Class ii aldolase
IC772_RS17735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC772_RS17750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC772_RS17765	COG0318	PFAM AMP-dependent synthetase and ligase
IC772_RS17775	COG0477	Major facilitator Superfamily
IC772_RS17780	COG2860	membrane
IC772_RS17790	COG1253	flavin adenine dinucleotide binding
IC772_RS17800	COG2814	Major facilitator Superfamily
IC772_RS17810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC772_RS17845	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC772_RS17860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC772_RS17895	COG1309	transcriptional regulator
IC772_RS17930	COG0758	DNA mediated transformation
IC772_RS17940	COG0697	spore germination
IC772_RS17945	COG1309	transcriptional regulator
IC772_RS17960	COG0386	Belongs to the glutathione peroxidase family
IC772_RS17970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC772_RS17975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC772_RS18025	COG1121	(ABC) transporter
IC772_RS18030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC772_RS18035	COG1280	lysine exporter protein (LysE YggA)
IC772_RS18040	COG2837	iron assimilation
IC772_RS18050	COG0281	malic enzyme
IC772_RS18085	COG0735	belongs to the Fur family
IC772_RS18105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IC772_RS18110	COG0519	Catalyzes the synthesis of GMP from XMP
IC772_RS18110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC772_RS18115	COG4399	Belongs to the UPF0754 family
IC772_RS18120	COG2259	Doxx family
IC772_RS18125	COG0586	Pfam SNARE associated Golgi protein
IC772_RS18140	COG1192	Involved in chromosome partitioning
IC772_RS18150	COG0271	Belongs to the BolA IbaG family
IC772_RS18190	COG3321	synthase
IC772_RS18190	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC772_RS18190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC772_RS18190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC772_RS18195	COG1960	acyl-CoA dehydrogenase activity
IC772_RS18200	COG0318	PFAM AMP-dependent synthetase and ligase
IC772_RS18205	COG2197	response regulator
IC772_RS18215	COG3916	Acyl-homoserine-lactone synthase
IC772_RS18220	COG0477	Major facilitator Superfamily
IC772_RS18225	COG1024	Enoyl-CoA hydratase
IC772_RS18230	COG1024	Enoyl-CoA hydratase
IC772_RS18235	COG1960	acyl-CoA dehydrogenase activity
IC772_RS18240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC772_RS18260	COG1113	amino acid transport
IC772_RS18265	COG1113	amino acid transport
IC772_RS18270	COG0251	oxidation-reduction process
IC772_RS18310	COG0564	pseudouridine synthase activity
IC772_RS18440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC772_RS18455	COG1802	Transcriptional regulator
IC772_RS18465	COG1448	Aminotransferase
IC772_RS18470	COG0277	FAD linked oxidase domain protein
IC772_RS18480	COG2186	Transcriptional regulator
IC772_RS18485	COG1620	l-lactate permease
IC772_RS18490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC772_RS18500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC772_RS18515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC772_RS18520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC772_RS18525	COG1216	Glycosyl transferase, family 2
IC772_RS18540	COG1215	transferase activity, transferring glycosyl groups
IC772_RS18540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IC772_RS18545	COG1442	glycosyl transferase family 8
IC772_RS18545	COG1216	Glycosyl transferase, family 2
IC772_RS18555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC772_RS18560	COG1596	polysaccharide export
IC772_RS18590	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC772_RS18650	COG0546	phosphoglycolate phosphatase activity
IC772_RS18655	COG1028	Short-chain dehydrogenase reductase Sdr
IC772_RS18670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC772_RS18670	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC772_RS18675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC772_RS18680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC772_RS18685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC772_RS18690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC772_RS18695	COG1116	anion transmembrane transporter activity
IC772_RS18700	COG1309	transcriptional regulator
IC772_RS18705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC772_RS18715	COG0196	riboflavin kinase activity
IC772_RS18720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC772_RS18730	COG1047	Peptidyl-prolyl cis-trans
IC772_RS18770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC772_RS18775	COG0657	acetylesterase activity
IC772_RS18825	COG2951	lytic endotransglycosylase activity
IC772_RS18830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC772_RS18845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC772_RS18855	COG0671	phosphoesterase, PA-phosphatase related
IC772_RS18860	COG0861	Integral membrane protein TerC family
IC772_RS18875	COG0402	S-adenosylhomocysteine deaminase activity
IC772_RS18890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process