locus-tag	class	description
IC763_RS00010	COG0592	DNA-directed DNA polymerase activity
IC763_RS00020	COG0187	DNA topoisomerase II activity
IC763_RS00030	COG0586	Pfam SNARE associated Golgi protein
IC763_RS00035	COG0488	(ABC) transporter
IC763_RS00065	COG3328	transposase activity
IC763_RS00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC763_RS00110	COG0625	glutathione transferase activity
IC763_RS00160	COG2233	PERMEase
IC763_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_RS00215	COG2814	Major facilitator Superfamily
IC763_RS00220	COG0656	L-ascorbic acid biosynthetic process
IC763_RS00225	COG0583	DNA-binding transcription factor activity
IC763_RS00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_RS00245	COG1064	alcohol dehydrogenase
IC763_RS00250	COG2818	Glycosylase
IC763_RS00265	COG1194	a g-specific adenine glycosylase
IC763_RS00280	COG5487	UPF0391 membrane protein
IC763_RS00285	COG2983	Belongs to the UPF0260 family
IC763_RS00290	COG2133	pyrroloquinoline quinone binding
IC763_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC763_RS00300	COG2116	formate transmembrane transporter activity
IC763_RS00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC763_RS00325	COG1335	isochorismatase
IC763_RS00330	COG0385	Bile acid
IC763_RS00335	COG0534	Mate efflux family protein
IC763_RS00340	COG1683	Conserved Protein
IC763_RS00355	COG0346	lactoylglutathione lyase activity
IC763_RS00360	COG0625	glutathione transferase activity
IC763_RS00370	COG1113	amino acid transport
IC763_RS00380	COG0523	cobalamin synthesis protein
IC763_RS00390	COG2188	Transcriptional regulator
IC763_RS00420	COG0010	Belongs to the arginase family
IC763_RS00450	COG3328	transposase activity
IC763_RS00475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC763_RS00485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC763_RS00490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC763_RS00585	COG0534	Mate efflux family protein
IC763_RS00590	COG0436	Aminotransferase
IC763_RS00595	COG2733	membrane
IC763_RS00610	COG2918	glutathione biosynthetic process
IC763_RS00670	COG3150	esterase
IC763_RS00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_RS00700	COG2233	PERMEase
IC763_RS00705	COG2351	hydroxyisourate hydrolase activity
IC763_RS00765	COG1393	Belongs to the ArsC family
IC763_RS00770	COG0708	Exodeoxyribonuclease III
IC763_RS00795	COG0189	ligase activity
IC763_RS00815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC763_RS00825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC763_RS00840	COG4942	peptidase
IC763_RS00850	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_RS00860	COG2119	membrane
IC763_RS00865	COG0426	domain, Protein
IC763_RS00865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_RS00915	COG1902	pentaerythritol trinitrate reductase activity
IC763_RS00925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC763_RS00930	COG0668	transmembrane transport
IC763_RS00940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC763_RS00945	COG1335	isochorismatase
IC763_RS00950	COG1522	sequence-specific DNA binding
IC763_RS00980	COG3162	membrane
IC763_RS00985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC763_RS01015	COG1309	transcriptional regulator
IC763_RS01035	COG4221	oxidoreductase activity
IC763_RS01045	COG0351	phosphomethylpyrimidine kinase
IC763_RS01045	COG0352	thiamine-phosphate diphosphorylase activity
IC763_RS01045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC763_RS01055	COG2814	Major facilitator Superfamily
IC763_RS01070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC763_RS01080	COG1113	amino acid transport
IC763_RS01090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC763_RS01095	COG1012	belongs to the aldehyde dehydrogenase family
IC763_RS01105	COG1335	isochorismatase
IC763_RS01165	COG0667	Aldo Keto reductase
IC763_RS01215	COG1733	regulation of RNA biosynthetic process
IC763_RS01220	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC763_RS01235	COG3177	Filamentation induced by cAMP protein fic
IC763_RS01305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC763_RS01365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC763_RS01380	COG2329	Antibiotic biosynthesis monooxygenase
IC763_RS01415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC763_RS01445	COG0427	acetyl-CoA hydrolase
IC763_RS01470	COG0659	secondary active sulfate transmembrane transporter activity
IC763_RS01475	COG4221	oxidoreductase activity
IC763_RS01485	COG0028	Belongs to the TPP enzyme family
IC763_RS01490	COG0488	(ABC) transporter
IC763_RS01565	COG0833	amino acid
IC763_RS01610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC763_RS01615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC763_RS01630	COG2226	methyltransferase
IC763_RS01685	COG0493	'glutamate synthase
IC763_RS01695	COG1704	LemA family
IC763_RS01700	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC763_RS01710	COG4969	Belongs to the N-Me-Phe pilin family
IC763_RS01720	COG3307	-O-antigen
IC763_RS01740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC763_RS01755	COG0194	GDP metabolic process
IC763_RS01770	COG4969	Belongs to the N-Me-Phe pilin family
IC763_RS01795	COG4969	Belongs to the N-Me-Phe pilin family
IC763_RS01810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC763_RS01820	COG0335	large ribosomal subunit rRNA binding
IC763_RS01830	COG5380	lipid catabolic process
IC763_RS01835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC763_RS01860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC763_RS01875	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC763_RS01880	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC763_RS01895	COG1289	transmembrane transporter activity
IC763_RS01905	COG0628	permease
IC763_RS01910	COG1192	Involved in chromosome partitioning
IC763_RS01945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC763_RS01950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC763_RS01960	COG1012	belongs to the aldehyde dehydrogenase family
IC763_RS02005	COG1794	racemase activity, acting on amino acids and derivatives
IC763_RS02010	COG0583	DNA-binding transcription factor activity
IC763_RS02030	COG0752	glycyl-tRNA synthetase alpha subunit
IC763_RS02055	COG0517	IMP dehydrogenase activity
IC763_RS02055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC763_RS02055	COG0617	tRNA 3'-terminal CCA addition
IC763_RS02060	COG1983	PspC domain protein
IC763_RS02070	COG1960	acyl-CoA dehydrogenase activity
IC763_RS02085	COG0408	coproporphyrinogen oxidase activity
IC763_RS02105	COG0513	Belongs to the DEAD box helicase family
IC763_RS02110	COG1127	ABC transporter
IC763_RS02115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC763_RS02125	COG2854	intermembrane phospholipid transfer
IC763_RS02135	COG0598	Magnesium transport protein CorA
IC763_RS02145	COG0494	nUDIX hydrolase
IC763_RS02150	COG1040	competence protein
IC763_RS02155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC763_RS02170	COG2937	Belongs to the GPAT DAPAT family
IC763_RS02175	COG1946	Acyl-CoA thioesterase
IC763_RS02180	COG1301	dicarboxylic acid transport
IC763_RS02195	COG1959	2 iron, 2 sulfur cluster binding
IC763_RS02205	COG0433	COG0433 Predicted ATPase
IC763_RS02210	COG0626	cystathionine gamma-synthase activity
IC763_RS02225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC763_RS02230	COG0088	Forms part of the polypeptide exit tunnel
IC763_RS02365	COG1960	acyl-CoA dehydrogenase activity
IC763_RS02400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC763_RS02405	COG0339	signal peptide processing
IC763_RS02410	COG0557	exoribonuclease II activity
IC763_RS02455	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC763_RS02460	COG2169	Transcriptional regulator
IC763_RS02470	COG1295	ribonuclease BN
IC763_RS02505	COG1702	phosphate starvation-inducible protein PhoH
IC763_RS02515	COG0739	heme binding
IC763_RS02515	COG0741	lytic transglycosylase activity
IC763_RS02515	COG1196	nuclear chromosome segregation
IC763_RS02545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC763_RS02550	COG1183	phosphatidylcholine synthase activity
IC763_RS02600	COG1960	acyl-CoA dehydrogenase activity
IC763_RS02605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC763_RS02610	COG1309	transcriptional regulator
IC763_RS02625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC763_RS02630	COG1960	acyl-CoA dehydrogenase activity
IC763_RS02635	COG1024	Enoyl-CoA hydratase
IC763_RS02635	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC763_RS02670	COG2969	positive regulation of protein catabolic process
IC763_RS02680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC763_RS02690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC763_RS02695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC763_RS02700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC763_RS02720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC763_RS02735	COG1408	metallophosphoesterase
IC763_RS02745	COG2199	diguanylate cyclase activity
IC763_RS02780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC763_RS02805	COG1607	acyl-coa hydrolase
IC763_RS02840	COG2350	Protein conserved in bacteria
IC763_RS02855	COG3781	membrane
IC763_RS02865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC763_RS02870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC763_RS02880	COG1862	Preprotein translocase
IC763_RS02930	COG0629	single-stranded DNA binding
IC763_RS02980	COG3646	Phage regulatory protein
IC763_RS03135	COG4695	Portal protein
IC763_RS03150	COG3328	transposase activity
IC763_RS03160	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC763_RS03175	COG2194	sulfuric ester hydrolase activity
IC763_RS03185	COG0726	polysaccharide deacetylase
IC763_RS03195	COG0438	transferase activity, transferring glycosyl groups
IC763_RS03235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC763_RS03270	COG1960	acyl-CoA dehydrogenase activity
IC763_RS03285	COG2205	protein histidine kinase activity
IC763_RS03290	COG0745	RESPONSE REGULATOR receiver
IC763_RS03300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC763_RS03325	COG4206	TonB-dependent receptor
IC763_RS03395	COG0450	alkyl hydroperoxide reductase
IC763_RS03410	COG0477	Major facilitator Superfamily
IC763_RS03415	COG1272	protein, Hemolysin III
IC763_RS03425	COG2153	protein acetylation
IC763_RS03450	COG2207	Transcriptional regulator
IC763_RS03470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_RS03485	COG0183	Belongs to the thiolase family
IC763_RS03495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC763_RS03495	COG2885	chlorophyll binding
IC763_RS03505	COG1690	Belongs to the RtcB family
IC763_RS03520	COG2233	PERMEase
IC763_RS03550	COG2094	Belongs to the DNA glycosylase MPG family
IC763_RS03560	COG1902	pentaerythritol trinitrate reductase activity
IC763_RS03565	COG0679	Auxin Efflux Carrier
IC763_RS03580	COG0354	folic acid binding
IC763_RS03595	COG2233	PERMEase
IC763_RS03600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_RS03605	COG0251	oxidation-reduction process
IC763_RS03610	COG1335	isochorismatase
IC763_RS03615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS03620	COG0778	Nitroreductase
IC763_RS03625	COG0596	Alpha beta hydrolase
IC763_RS03630	COG3189	MarR family transcriptional regulator
IC763_RS03635	COG2824	Alkylphosphonate utilization operon protein PhnA
IC763_RS03640	COG3422	double-strand break repair
IC763_RS03680	COG0840	transmembrane signaling receptor activity
IC763_RS03695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC763_RS03720	COG2832	Protein of unknown function (DUF454)
IC763_RS03725	COG1376	ErfK ybiS ycfS ynhG family protein
IC763_RS03775	COG1289	transmembrane transporter activity
IC763_RS03780	COG2814	Major facilitator Superfamily
IC763_RS03800	COG1115	amino acid carrier protein
IC763_RS03805	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC763_RS03810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC763_RS03815	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC763_RS03845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC763_RS03855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC763_RS03860	COG1077	Cell shape determining protein MreB Mrl
IC763_RS03865	COG1792	Involved in formation and maintenance of cell shape
IC763_RS03870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC763_RS03875	COG0424	maF-like protein
IC763_RS03880	COG1530	ribonuclease E activity
IC763_RS03890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC763_RS03910	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC763_RS03935	COG2207	Transcriptional regulator
IC763_RS04275	COG0582	viral genome integration into host DNA
IC763_RS04295	COG3046	protein related to deoxyribodipyrimidine photolyase
IC763_RS04300	COG2816	NAD+ diphosphatase activity
IC763_RS04315	COG0142	geranyltranstransferase activity
IC763_RS04320	COG2315	Protein conserved in bacteria
IC763_RS04335	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC763_RS04355	COG2194	sulfuric ester hydrolase activity
IC763_RS04360	COG0745	RESPONSE REGULATOR receiver
IC763_RS04365	COG0642	Histidine kinase
IC763_RS04375	COG0004	ammonium transporteR
IC763_RS04400	COG0525	valine-tRNA ligase activity
IC763_RS04410	COG0525	valine-tRNA ligase activity
IC763_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS04430	COG0393	Putative heavy-metal-binding
IC763_RS04435	COG0393	Putative heavy-metal-binding
IC763_RS04440	COG1538	Outer membrane efflux protein
IC763_RS04450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_RS04455	COG0671	phosphoesterase, PA-phosphatase related
IC763_RS04485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC763_RS04500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC763_RS04500	COG1648	precorrin-2 dehydrogenase activity
IC763_RS04505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC763_RS04520	COG0531	amino acid
IC763_RS04535	COG0321	lipoyl(octanoyl) transferase activity
IC763_RS04540	COG2921	Belongs to the UPF0250 family
IC763_RS04575	COG2009	succinate dehydrogenase
IC763_RS04585	COG1053	succinate dehydrogenase
IC763_RS04590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC763_RS04640	COG2321	neutral zinc metallopeptidase
IC763_RS04665	COG2843	Capsule synthesis protein
IC763_RS04685	COG0589	response to stress
IC763_RS04705	COG0505	Belongs to the CarA family
IC763_RS04730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC763_RS04735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC763_RS04785	COG0477	Major facilitator Superfamily
IC763_RS04790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC763_RS04930	COG0732	type I restriction modification DNA specificity domain
IC763_RS04965	COG0584	glycerophosphoryl diester phosphodiesterase
IC763_RS04985	COG0741	lytic transglycosylase activity
IC763_RS05005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC763_RS05010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC763_RS05055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC763_RS05075	COG3811	Belongs to the UPF0386 family
IC763_RS05130	COG1309	transcriptional regulator
IC763_RS05135	COG1902	pentaerythritol trinitrate reductase activity
IC763_RS05140	COG0596	Alpha beta hydrolase
IC763_RS05140	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_RS05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_RS05145	COG0596	Alpha beta hydrolase
IC763_RS05150	COG0596	Alpha beta hydrolase
IC763_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS05160	COG0583	DNA-binding transcription factor activity
IC763_RS05165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC763_RS05170	COG1012	belongs to the aldehyde dehydrogenase family
IC763_RS05190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_RS05195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_RS05200	COG0778	Nitroreductase
IC763_RS05215	COG1929	Belongs to the glycerate kinase type-1 family
IC763_RS05220	COG0243	molybdopterin cofactor binding
IC763_RS05225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC763_RS05230	COG3339	Conserved Protein
IC763_RS05260	COG1113	amino acid transport
IC763_RS05270	COG0019	diaminopimelate decarboxylase activity
IC763_RS05285	COG1280	lysine exporter protein (LysE YggA)
IC763_RS05290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC763_RS05310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC763_RS05330	COG0463	Glycosyl transferase, family 2
IC763_RS05350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_RS05385	COG1136	(ABC) transporter
IC763_RS05400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC763_RS05400	COG0616	signal peptide processing
IC763_RS05405	COG0596	Alpha beta hydrolase
IC763_RS05410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC763_RS05420	COG0628	permease
IC763_RS05455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC763_RS05475	COG0823	Involved in the tonB-independent uptake of proteins
IC763_RS05495	COG0824	Thioesterase
IC763_RS05525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC763_RS05525	COG0047	phosphoribosylformylglycinamidine synthase activity
IC763_RS05535	COG2814	Major facilitator Superfamily
IC763_RS05555	COG1024	Enoyl-CoA hydratase
IC763_RS05560	COG1056	cytidyltransferase-related domain
IC763_RS05560	COG1051	belongs to the nudix hydrolase family
IC763_RS05575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC763_RS05590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC763_RS05595	COG0602	queuosine metabolic process
IC763_RS05605	COG4625	pathogenesis
IC763_RS05610	COG0583	DNA-binding transcription factor activity
IC763_RS05615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC763_RS05620	COG4208	sulfate ABC transporter
IC763_RS05625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC763_RS05635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC763_RS05645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC763_RS05665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC763_RS05675	COG0481	GTPase activity
IC763_RS05680	COG0681	Belongs to the peptidase S26 family
IC763_RS05695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC763_RS05705	COG1381	Involved in DNA repair and RecF pathway recombination
IC763_RS05710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC763_RS05720	COG4221	oxidoreductase activity
IC763_RS05745	COG0436	Aminotransferase
IC763_RS05765	COG3706	GGDEF domain
IC763_RS05770	COG0556	nucleotide-excision repair
IC763_RS05825	COG2070	2-Nitropropane dioxygenase
IC763_RS05840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC763_RS05880	COG1252	NADH dehydrogenase
IC763_RS05885	COG1686	Belongs to the peptidase S11 family
IC763_RS05900	COG1187	pseudouridine synthase activity
IC763_RS06015	COG0305	Participates in initiation and elongation during chromosome replication
IC763_RS06130	COG3328	transposase activity
IC763_RS06150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IC763_RS06185	COG0477	Major facilitator Superfamily
IC763_RS06195	COG1823	symporter activity
IC763_RS06230	COG0352	thiamine-phosphate diphosphorylase activity
IC763_RS06265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_RS06290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC763_RS06310	COG3961	Belongs to the TPP enzyme family
IC763_RS06315	COG1113	amino acid transport
IC763_RS06325	COG0573	inorganic phosphate transmembrane transporter activity
IC763_RS06335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC763_RS06355	COG3647	Membrane
IC763_RS06380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC763_RS06385	COG1686	Belongs to the peptidase S11 family
IC763_RS06410	COG0583	DNA-binding transcription factor activity
IC763_RS06415	COG1067	ATP-dependent peptidase activity
IC763_RS06455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC763_RS06460	COG1966	Carbon starvation protein
IC763_RS06465	COG2879	small protein
IC763_RS06505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC763_RS06535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC763_RS06540	COG2423	ornithine cyclodeaminase activity
IC763_RS06550	COG2964	Protein conserved in bacteria
IC763_RS06565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC763_RS06575	COG1741	Belongs to the pirin family
IC763_RS06610	COG0302	gtp cyclohydrolase
IC763_RS06620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC763_RS06630	COG2840	Smr protein MutS2
IC763_RS06645	COG0512	Glutamine amidotransferase of anthranilate synthase
IC763_RS06660	COG0174	glutamine synthetase
IC763_RS06670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC763_RS06705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC763_RS06710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC763_RS06715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC763_RS06740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC763_RS06760	COG1960	acyl-CoA dehydrogenase activity
IC763_RS06765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC763_RS06770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC763_RS06780	COG2223	nitrite transmembrane transporter activity
IC763_RS06790	COG0024	Methionine aminopeptidase
IC763_RS06795	COG0052	Belongs to the universal ribosomal protein uS2 family
IC763_RS06835	COG2951	lytic endotransglycosylase activity
IC763_RS06840	COG0772	Belongs to the SEDS family
IC763_RS06855	COG0842	Transport permease protein
IC763_RS06865	COG0582	viral genome integration into host DNA
IC763_RS07020	COG1538	Outer membrane efflux protein
IC763_RS07030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_RS07045	COG4215	(ABC) transporter
IC763_RS07050	COG4160	amino acid transport
IC763_RS07055	COG4598	ABC transporter
IC763_RS07065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC763_RS07070	COG0826	peptidase U32
IC763_RS07075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_RS07085	COG2801	Transposase and inactivated derivatives
IC763_RS07125	COG0642	Histidine kinase
IC763_RS07135	COG0494	nUDIX hydrolase
IC763_RS07145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC763_RS07150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC763_RS07155	COG3139	Protein of unknown function (DUF1315)
IC763_RS07165	COG1301	dicarboxylic acid transport
IC763_RS07170	COG1960	acyl-CoA dehydrogenase activity
IC763_RS07190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC763_RS07200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC763_RS07205	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC763_RS07225	COG1690	Belongs to the RtcB family
IC763_RS07230	COG1234	tRNA 3'-trailer cleavage
IC763_RS07260	COG2363	Small membrane protein
IC763_RS07290	COG0778	Nitroreductase
IC763_RS07350	COG1610	YqeY-like protein
IC763_RS07380	COG0515	serine threonine protein kinase
IC763_RS07380	COG2815	serine threonine protein kinase
IC763_RS07405	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IC763_RS07500	COG1335	isochorismatase
IC763_RS07505	COG0583	DNA-binding transcription factor activity
IC763_RS07520	COG0596	Alpha beta hydrolase
IC763_RS07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC763_RS07540	COG0786	glutamate:sodium symporter activity
IC763_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS07655	COG2985	domain, Protein
IC763_RS07680	COG2995	paraquat-inducible protein a
IC763_RS07685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC763_RS07685	COG3008	intermembrane lipid transfer
IC763_RS07695	COG2351	hydroxyisourate hydrolase activity
IC763_RS07710	COG5002	protein histidine kinase activity
IC763_RS07755	COG0745	RESPONSE REGULATOR receiver
IC763_RS07780	COG2175	clavaminate synthase activity
IC763_RS07785	COG3246	L-lysine catabolic process to acetate
IC763_RS07790	COG2814	Major facilitator Superfamily
IC763_RS07805	COG2855	membrane
IC763_RS07850	COG1301	dicarboxylic acid transport
IC763_RS07865	COG2011	ABC-type metal ion transport system permease component
IC763_RS07870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC763_RS07875	COG1464	Belongs to the NlpA lipoprotein family
IC763_RS07880	COG0151	Belongs to the GarS family
IC763_RS07885	COG0138	bifunctional purine biosynthesis protein purh
IC763_RS07890	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC763_RS07920	COG2308	Evidence 4 Homologs of previously reported genes of
IC763_RS07930	COG1305	Transglutaminase-like
IC763_RS07940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC763_RS07945	COG0305	Participates in initiation and elongation during chromosome replication
IC763_RS07970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC763_RS07980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC763_RS08015	COG0726	polysaccharide deacetylase
IC763_RS08015	COG1649	PFAM Uncharacterised BCR, COG1649
IC763_RS08020	COG1215	transferase activity, transferring glycosyl groups
IC763_RS08025	COG3658	cytochrome
IC763_RS08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS08060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_RS08065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_RS08080	COG1960	acyl-CoA dehydrogenase activity
IC763_RS08090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_RS08115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC763_RS08120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC763_RS08125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC763_RS08130	COG2205	protein histidine kinase activity
IC763_RS08135	COG0745	RESPONSE REGULATOR receiver
IC763_RS08140	COG0174	glutamine synthetase
IC763_RS08160	COG0729	surface antigen
IC763_RS08190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC763_RS08195	COG2814	Major facilitator Superfamily
IC763_RS08205	COG0583	DNA-binding transcription factor activity
IC763_RS08220	COG1187	pseudouridine synthase activity
IC763_RS08240	COG0802	atpase or kinase
IC763_RS08245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC763_RS08255	COG1923	regulation of RNA biosynthetic process
IC763_RS08260	COG0697	spore germination
IC763_RS08285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC763_RS08290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC763_RS08290	COG0519	Catalyzes the synthesis of GMP from XMP
IC763_RS08295	COG4302	ethanolamine ammonia-lyase activity
IC763_RS08300	COG4303	Ethanolamine ammonia lyase large subunit
IC763_RS08325	COG1454	alcohol dehydrogenase
IC763_RS08330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_RS08340	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC763_RS08360	COG0308	aminopeptidase N
IC763_RS08390	COG1605	Chorismate mutase
IC763_RS08430	COG4264	IucA IucC family
IC763_RS08435	COG2423	ornithine cyclodeaminase activity
IC763_RS08440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC763_RS08450	COG0668	transmembrane transport
IC763_RS08525	COG1522	sequence-specific DNA binding
IC763_RS08535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC763_RS08540	COG0583	DNA-binding transcription factor activity
IC763_RS08560	COG2030	dehydratase
IC763_RS08565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC763_RS08600	COG0824	Thioesterase
IC763_RS08605	COG1454	alcohol dehydrogenase
IC763_RS08615	COG1335	isochorismatase
IC763_RS08630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC763_RS08695	COG2814	Major facilitator Superfamily
IC763_RS08710	COG0511	ligase activity, forming carbon-carbon bonds
IC763_RS08725	COG1116	anion transmembrane transporter activity
IC763_RS08725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_RS08730	COG0745	RESPONSE REGULATOR receiver
IC763_RS08740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_RS08740	COG2146	nitrite reductase [NAD(P)H] activity
IC763_RS08745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_RS08765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC763_RS08780	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC763_RS08780	COG0315	cyclic pyranopterin monophosphate synthase activity
IC763_RS08785	COG0303	'Molybdopterin
IC763_RS08795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_RS08820	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC763_RS08825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC763_RS08880	COG2204	response regulator
IC763_RS08910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC763_RS08915	COG0575	Belongs to the CDS family
IC763_RS08930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC763_RS08950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC763_RS08965	COG2137	regulation of response to DNA damage stimulus
IC763_RS08975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC763_RS08980	COG1011	Hydrolase
IC763_RS08995	COG1522	sequence-specific DNA binding
IC763_RS09065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC763_RS09065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC763_RS09065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC763_RS09070	COG1105	Belongs to the carbohydrate kinase PfkB family
IC763_RS09075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC763_RS09075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC763_RS09105	COG0024	Methionine aminopeptidase
IC763_RS09110	COG0583	DNA-binding transcription factor activity
IC763_RS09120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC763_RS09125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC763_RS09155	COG0552	protein localization to endoplasmic reticulum
IC763_RS09180	COG4890	Cyd operon protein YbgT
IC763_RS09185	COG1294	oxidase, subunit
IC763_RS09200	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC763_RS09210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC763_RS09215	COG4774	siderophore transport
IC763_RS09230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC763_RS09235	COG0569	domain protein
IC763_RS09240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC763_RS09270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC763_RS09275	COG0542	response to heat
IC763_RS09300	COG1902	pentaerythritol trinitrate reductase activity
IC763_RS09300	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC763_RS09340	COG0148	phosphopyruvate hydratase activity
IC763_RS09345	COG2323	membrane
IC763_RS09355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC763_RS09365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC763_RS09370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC763_RS09375	COG0183	Belongs to the thiolase family
IC763_RS09385	COG0596	Alpha beta hydrolase
IC763_RS09390	COG2271	Major facilitator Superfamily
IC763_RS09395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC763_RS09405	COG3485	protocatechuate 3,4-dioxygenase
IC763_RS09415	COG3420	alginic acid biosynthetic process
IC763_RS09420	COG3659	wide pore channel activity
IC763_RS09425	COG4993	Dehydrogenase
IC763_RS09435	COG2391	methyltransferase activity
IC763_RS09450	COG1414	Transcriptional regulator
IC763_RS09455	COG0583	DNA-binding transcription factor activity
IC763_RS09460	COG1960	acyl-CoA dehydrogenase activity
IC763_RS09485	COG2814	Major facilitator Superfamily
IC763_RS09495	COG0154	amidase activity
IC763_RS09515	COG4638	Rieske (2fe-2S)
IC763_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS09535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_RS09545	COG3733	amine oxidase
IC763_RS09565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC763_RS09570	COG0183	Belongs to the thiolase family
IC763_RS09575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC763_RS09580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC763_RS09590	COG4829	muconolactone delta-isomerase
IC763_RS09595	COG4948	Mandelate Racemase Muconate Lactonizing
IC763_RS09600	COG0583	DNA-binding transcription factor activity
IC763_RS09655	COG1309	transcriptional regulator
IC763_RS09740	COG2271	Major facilitator Superfamily
IC763_RS09780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC763_RS09785	COG1120	ATPase activity
IC763_RS09805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC763_RS09885	COG2431	L-lysine efflux transmembrane transporter activity
IC763_RS10030	COG2801	Transposase and inactivated derivatives
IC763_RS10060	COG0667	Aldo Keto reductase
IC763_RS10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS10080	COG2175	clavaminate synthase activity
IC763_RS10110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_RS10115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS10120	COG4771	TonB-dependent receptor
IC763_RS10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS10160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_RS10165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_RS10180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC763_RS10185	COG0805	protein transport
IC763_RS10195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS10220	COG1132	(ABC) transporter
IC763_RS10245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC763_RS10250	COG0601	transmembrane transport
IC763_RS10280	COG3539	Fimbrial protein
IC763_RS10305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC763_RS10325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC763_RS10330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC763_RS10340	COG2205	protein histidine kinase activity
IC763_RS10345	COG0745	RESPONSE REGULATOR receiver
IC763_RS10350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_RS10355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_RS10415	COG4771	TonB-dependent receptor
IC763_RS10420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_RS10435	COG1169	isochorismate synthase
IC763_RS10445	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS10455	COG3251	PFAM MbtH domain protein
IC763_RS10485	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC763_RS10495	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC763_RS10505	COG4638	Rieske (2fe-2S)
IC763_RS10510	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC763_RS10515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_RS10515	COG0543	2 iron, 2 sulfur cluster binding
IC763_RS10530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS10560	COG2207	Transcriptional regulator
IC763_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS10570	COG2610	gluconate transmembrane transporter activity
IC763_RS10575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC763_RS10610	COG2814	Major facilitator Superfamily
IC763_RS10630	COG0583	DNA-binding transcription factor activity
IC763_RS10645	COG2031	fatty acid transporter
IC763_RS10650	COG0183	Belongs to the thiolase family
IC763_RS10655	COG0583	DNA-binding transcription factor activity
IC763_RS10660	COG0583	DNA-binding transcription factor activity
IC763_RS10675	COG1027	Aspartate ammonia-lyase
IC763_RS10685	COG0477	Major facilitator Superfamily
IC763_RS10695	COG2207	Transcriptional regulator
IC763_RS10695	COG3708	Transcriptional regulator
IC763_RS10710	COG0730	response to heat
IC763_RS10720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC763_RS10720	COG3453	Protein conserved in bacteria
IC763_RS10730	COG3781	membrane
IC763_RS10735	COG1063	alcohol dehydrogenase
IC763_RS10750	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_RS10755	COG0022	dehydrogenase e1 component
IC763_RS10760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC763_RS10770	COG3293	Transposase
IC763_RS10790	COG3706	GGDEF domain
IC763_RS10805	COG0133	tryptophan synthase activity
IC763_RS10815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC763_RS10850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC763_RS10875	COG2226	methyltransferase
IC763_RS10925	COG0842	Transport permease protein
IC763_RS10930	COG0842	Transport permease protein
IC763_RS10935	COG1131	(ABC) transporter
IC763_RS10950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC763_RS10955	COG4773	Receptor
IC763_RS10975	COG0730	response to heat
IC763_RS10995	COG0406	alpha-ribazole phosphatase activity
IC763_RS11020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC763_RS11035	COG1960	acyl-CoA dehydrogenase activity
IC763_RS11040	COG1960	acyl-CoA dehydrogenase activity
IC763_RS11045	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_RS11050	COG2207	Transcriptional regulator
IC763_RS11060	COG0776	regulation of translation
IC763_RS11085	COG0822	iron-sulfur transferase activity
IC763_RS11090	COG0316	Belongs to the HesB IscA family
IC763_RS11140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC763_RS11145	COG0702	epimerase
IC763_RS11175	COG4172	Belongs to the ABC transporter superfamily
IC763_RS11180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC763_RS11185	COG0601	transmembrane transport
IC763_RS11210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC763_RS11240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC763_RS11255	COG2431	L-lysine efflux transmembrane transporter activity
IC763_RS11270	COG0776	regulation of translation
IC763_RS11335	COG0084	hydrolase, TatD family'
IC763_RS11360	COG1132	(ABC) transporter
IC763_RS11375	COG1475	DNA binding
IC763_RS11380	COG1192	Involved in chromosome partitioning
IC763_RS11390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC763_RS11430	COG0424	maF-like protein
IC763_RS11455	COG3619	membrane
IC763_RS11465	COG3328	transposase activity
IC763_RS11470	COG1132	(ABC) transporter
IC763_RS11505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC763_RS11515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC763_RS11515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC763_RS11515	COG0506	proline dehydrogenase activity
IC763_RS11520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC763_RS11535	COG3698	Phosphodiester glycosidase
IC763_RS11545	COG2353	YceI-like domain
IC763_RS11560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC763_RS11600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC763_RS11600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC763_RS11625	COG3539	Fimbrial protein
IC763_RS11630	COG3121	Chaperone
IC763_RS11650	COG0697	spore germination
IC763_RS11660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC763_RS11670	COG0583	DNA-binding transcription factor activity
IC763_RS11690	COG2197	response regulator
IC763_RS11715	COG1522	sequence-specific DNA binding
IC763_RS11725	COG1126	abc transporter atp-binding protein
IC763_RS11730	COG0765	amino acid transport
IC763_RS11735	COG0765	amino acid transport
IC763_RS11765	COG1464	Belongs to the NlpA lipoprotein family
IC763_RS11775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC763_RS11780	COG2011	ABC-type metal ion transport system permease component
IC763_RS11785	COG0012	GTP binding
IC763_RS11810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC763_RS11850	COG0386	Belongs to the glutathione peroxidase family
IC763_RS11860	COG0436	Aminotransferase
IC763_RS11865	COG1301	dicarboxylic acid transport
IC763_RS11900	COG3634	alkyl hydroperoxide reductase activity
IC763_RS11915	COG0583	DNA-binding transcription factor activity
IC763_RS11925	COG0210	DNA helicase
IC763_RS12045	COG3328	transposase activity
IC763_RS12065	COG0640	Transcriptional regulator
IC763_RS12080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC763_RS12090	COG0583	DNA-binding transcription factor activity
IC763_RS12100	COG1953	Uracil, thiamine, allantoin
IC763_RS12110	COG2175	clavaminate synthase activity
IC763_RS12115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_RS12120	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC763_RS12125	COG4521	taurine ABC transporter
IC763_RS12135	COG0477	Major facilitator Superfamily
IC763_RS12155	COG1271	oxidase subunit
IC763_RS12160	COG1294	oxidase, subunit
IC763_RS12170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_RS12190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC763_RS12210	COG3052	prosthetic group binding
IC763_RS12215	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC763_RS12240	COG1346	cytolysis
IC763_RS12250	COG0583	DNA-binding transcription factor activity
IC763_RS12255	COG0625	glutathione transferase activity
IC763_RS12260	COG0625	glutathione transferase activity
IC763_RS12265	COG0583	DNA-binding transcription factor activity
IC763_RS12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC763_RS12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC763_RS12310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC763_RS12320	COG0765	amino acid transport
IC763_RS12325	COG0765	amino acid transport
IC763_RS12385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC763_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS12450	COG0583	DNA-binding transcription factor activity
IC763_RS12470	COG0318	PFAM AMP-dependent synthetase and ligase
IC763_RS12475	COG1309	transcriptional regulator
IC763_RS12485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC763_RS12495	COG4770	biotin carboxylase activity
IC763_RS12505	COG0583	DNA-binding transcription factor activity
IC763_RS12520	COG1960	acyl-CoA dehydrogenase activity
IC763_RS12530	COG2814	Major facilitator Superfamily
IC763_RS12540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC763_RS12545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC763_RS12550	COG2814	Major facilitator Superfamily
IC763_RS12560	COG1024	Enoyl-CoA hydratase
IC763_RS12570	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC763_RS12575	COG0183	Belongs to the thiolase family
IC763_RS12585	COG2814	Major facilitator Superfamily
IC763_RS12600	COG1024	Enoyl-CoA hydratase
IC763_RS12610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC763_RS12615	COG1960	acyl-CoA dehydrogenase activity
IC763_RS12620	COG2814	Major facilitator Superfamily
IC763_RS12625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC763_RS12630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC763_RS12665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_RS12680	COG0583	DNA-binding transcription factor activity
IC763_RS12695	COG3038	cytochrome b561
IC763_RS12705	COG0531	amino acid
IC763_RS12710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC763_RS12725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC763_RS12730	COG1309	transcriptional regulator
IC763_RS12770	COG3179	chitinase
IC763_RS12790	COG0406	alpha-ribazole phosphatase activity
IC763_RS12800	COG2050	protein possibly involved in aromatic compounds catabolism
IC763_RS12810	COG3327	negative regulation of DNA-templated transcription, initiation
IC763_RS12815	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC763_RS12830	COG1024	Enoyl-CoA hydratase
IC763_RS12840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_RS12845	COG2151	metal-sulfur cluster biosynthetic enzyme
IC763_RS12850	COG3396	Phenylacetate-CoA oxygenase
IC763_RS12855	COG3460	Phenylacetate-CoA oxygenase
IC763_RS12860	COG3396	Phenylacetate-CoA oxygenase
IC763_RS12880	COG0789	Transcriptional regulator
IC763_RS12890	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC763_RS12895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_RS12910	COG2807	transmembrane transport
IC763_RS12915	COG0590	tRNA wobble adenosine to inosine editing
IC763_RS13020	COG0477	Major facilitator Superfamily
IC763_RS13035	COG1116	anion transmembrane transporter activity
IC763_RS13040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC763_RS13050	COG0864	Transcriptional regulator
IC763_RS13065	COG1733	regulation of RNA biosynthetic process
IC763_RS13075	COG0439	Biotin carboxylase
IC763_RS13090	COG1063	alcohol dehydrogenase
IC763_RS13125	COG0038	chloride channel
IC763_RS13130	COG4770	biotin carboxylase activity
IC763_RS13150	COG1914	H( )-stimulated, divalent metal cation uptake system
IC763_RS13155	COG0583	DNA-binding transcription factor activity
IC763_RS13165	COG1595	DNA-templated transcription, initiation
IC763_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS13205	COG2076	Multidrug Resistance protein
IC763_RS13220	COG3713	MltA-interacting MipA family protein
IC763_RS13290	COG1011	Hydrolase
IC763_RS13350	COG1309	transcriptional regulator
IC763_RS13355	COG1278	Cold shock
IC763_RS13365	COG0626	cystathionine gamma-synthase activity
IC763_RS13370	COG1522	sequence-specific DNA binding
IC763_RS13380	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS13390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC763_RS13395	COG4774	siderophore transport
IC763_RS13430	COG0402	S-adenosylhomocysteine deaminase activity
IC763_RS13435	COG0583	DNA-binding transcription factor activity
IC763_RS13450	COG1294	oxidase, subunit
IC763_RS13455	COG1469	GTP cyclohydrolase I activity
IC763_RS13520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC763_RS13530	COG4122	O-methyltransferase activity
IC763_RS13570	COG1538	Outer membrane efflux protein
IC763_RS13575	COG1137	ATPase activity
IC763_RS13580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC763_RS13590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC763_RS13595	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC763_RS13595	COG0517	IMP dehydrogenase activity
IC763_RS13635	COG2814	Major facilitator Superfamily
IC763_RS13665	COG1278	Cold shock
IC763_RS13670	COG1280	lysine exporter protein (LysE YggA)
IC763_RS13790	COG2871	sodium ion transport
IC763_RS13800	COG0583	DNA-binding transcription factor activity
IC763_RS13810	COG4638	Rieske (2fe-2S)
IC763_RS13815	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC763_RS13820	COG0633	Ferredoxin
IC763_RS13820	COG0543	2 iron, 2 sulfur cluster binding
IC763_RS13825	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS13830	COG3135	benzoate transporter
IC763_RS13865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_RS13875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IC763_RS13885	COG3634	alkyl hydroperoxide reductase activity
IC763_RS13905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC763_RS13910	COG0625	glutathione transferase activity
IC763_RS13970	COG1765	OsmC-like protein
IC763_RS13980	COG0667	Aldo Keto reductase
IC763_RS13995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC763_RS14010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC763_RS14020	COG0527	aspartate kinase activity
IC763_RS14030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC763_RS14040	COG3038	cytochrome b561
IC763_RS14050	COG2252	PERMEase
IC763_RS14075	COG1741	Belongs to the pirin family
IC763_RS14080	COG1309	transcriptional regulator
IC763_RS14095	COG2072	flavoprotein involved in K transport
IC763_RS14100	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC763_RS14105	COG0583	DNA-binding transcription factor activity
IC763_RS14120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC763_RS14170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_RS14190	COG1024	Enoyl-CoA hydratase
IC763_RS14195	COG1012	belongs to the aldehyde dehydrogenase family
IC763_RS14205	COG1960	acyl-CoA dehydrogenase activity
IC763_RS14225	COG0697	spore germination
IC763_RS14245	COG1113	amino acid transport
IC763_RS14285	COG0531	amino acid
IC763_RS14295	COG1113	amino acid transport
IC763_RS14330	COG3209	COG3209 Rhs family protein
IC763_RS14375	COG3293	Transposase
IC763_RS14405	COG0583	DNA-binding transcription factor activity
IC763_RS14415	COG0251	oxidation-reduction process
IC763_RS14430	COG1902	pentaerythritol trinitrate reductase activity
IC763_RS14430	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC763_RS14440	COG4251	negative regulation of phosphorylation
IC763_RS14440	COG3706	GGDEF domain
IC763_RS14440	COG5001	Diguanylate cyclase
IC763_RS14440	COG2203	Gaf domain
IC763_RS14450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC763_RS14475	COG4172	Belongs to the ABC transporter superfamily
IC763_RS14480	COG4239	(ABC) transporter, permease
IC763_RS14485	COG4174	ABC transporter (Permease)
IC763_RS14495	COG1388	LysM domain
IC763_RS14495	COG0741	lytic transglycosylase activity
IC763_RS14540	COG0583	DNA-binding transcription factor activity
IC763_RS14565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_RS14570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_RS14575	COG0006	proline dipeptidase activity
IC763_RS14610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC763_RS14635	COG3384	dioxygenase
IC763_RS14645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC763_RS14650	COG2878	Part of a membrane complex involved in electron transport
IC763_RS14655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC763_RS14680	COG0768	penicillin binding
IC763_RS14685	COG0742	ribosomal rna small subunit methyltransferase
IC763_RS14705	COG0830	nickel cation binding
IC763_RS14715	COG0804	urea catabolic process
IC763_RS14755	COG1253	flavin adenine dinucleotide binding
IC763_RS14760	COG2851	Citrate transporter
IC763_RS14810	COG1773	rubredoxin
IC763_RS14815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_RS14825	COG0583	DNA-binding transcription factor activity
IC763_RS14855	COG4181	ATPase activity
IC763_RS14910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC763_RS14930	COG0306	phosphate transporter
IC763_RS14975	COG2223	nitrite transmembrane transporter activity
IC763_RS14985	COG2066	Belongs to the glutaminase family
IC763_RS14990	COG0242	peptide deformylase activity
IC763_RS14995	COG0477	Major facilitator Superfamily
IC763_RS15005	COG0028	Belongs to the TPP enzyme family
IC763_RS15020	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS15025	COG2267	carboxylic ester hydrolase activity
IC763_RS15070	COG1414	Transcriptional regulator
IC763_RS15105	COG3328	transposase activity
IC763_RS15120	COG1215	transferase activity, transferring glycosyl groups
IC763_RS15125	COG1649	PFAM Uncharacterised BCR, COG1649
IC763_RS15125	COG0726	polysaccharide deacetylase
IC763_RS15135	COG4681	YaeQ
IC763_RS15145	COG0523	cobalamin synthesis protein
IC763_RS15155	COG1607	acyl-coa hydrolase
IC763_RS15165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC763_RS15170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC763_RS15175	COG1309	transcriptional regulator
IC763_RS15200	COG2040	homocysteine
IC763_RS15205	COG0531	amino acid
IC763_RS15225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC763_RS15310	COG0405	Gamma-glutamyltransferase
IC763_RS15315	COG2814	Major facilitator Superfamily
IC763_RS15325	COG2050	protein possibly involved in aromatic compounds catabolism
IC763_RS15340	COG1090	epimerase
IC763_RS15360	COG0420	3'-5' exonuclease activity
IC763_RS15370	COG1968	undecaprenyl-diphosphatase activity
IC763_RS15390	COG0735	belongs to the Fur family
IC763_RS15395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC763_RS15400	COG2914	Belongs to the UPF0125 (RnfH) family
IC763_RS15415	COG0121	glutamine amidotransferase
IC763_RS15430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC763_RS15445	COG2885	chlorophyll binding
IC763_RS15450	COG0204	Acyl-transferase
IC763_RS15465	COG2894	cell division
IC763_RS15480	COG1280	lysine exporter protein (LysE YggA)
IC763_RS15485	COG1674	ftsk spoiiie
IC763_RS15490	COG0492	ferredoxin-NADP+ reductase activity
IC763_RS15495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC763_RS15505	COG0456	acetyltransferase
IC763_RS15525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC763_RS15535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC763_RS15550	COG1981	membrane
IC763_RS15560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC763_RS15560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC763_RS15580	COG1012	belongs to the aldehyde dehydrogenase family
IC763_RS15585	COG4638	Rieske (2fe-2S)
IC763_RS15600	COG0473	3-isopropylmalate dehydrogenase activity
IC763_RS15605	COG0583	DNA-binding transcription factor activity
IC763_RS15625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC763_RS15650	COG0564	pseudouridine synthase activity
IC763_RS15660	COG0358	DNA primase activity
IC763_RS15675	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC763_RS15705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC763_RS15735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC763_RS15750	COG1652	LysM domain
IC763_RS15775	COG1399	metal-binding, possibly nucleic acid-binding protein
IC763_RS15780	COG3101	peptidyl-lysine hydroxylation
IC763_RS15785	COG0009	L-threonylcarbamoyladenylate synthase
IC763_RS15790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC763_RS15795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC763_RS15810	COG4106	trans-aconitate 2-methyltransferase activity
IC763_RS15825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC763_RS15825	COG0596	Alpha beta hydrolase
IC763_RS15825	COG2226	methyltransferase
IC763_RS15830	COG1877	trehalose-phosphatase activity
IC763_RS15835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC763_RS15840	COG2223	nitrite transmembrane transporter activity
IC763_RS15870	COG0730	response to heat
IC763_RS15885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC763_RS15895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC763_RS15940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC763_RS15945	COG0489	protein tyrosine kinase activity
IC763_RS15955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC763_RS15955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC763_RS15990	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC763_RS15995	COG2081	HI0933 family
IC763_RS16005	COG0668	transmembrane transport
IC763_RS16025	COG0583	DNA-binding transcription factor activity
IC763_RS16050	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC763_RS16055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC763_RS16070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC763_RS16085	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC763_RS16110	COG3706	GGDEF domain
IC763_RS16125	COG0745	RESPONSE REGULATOR receiver
IC763_RS16145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC763_RS16175	COG3328	transposase activity
IC763_RS16180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC763_RS16195	COG0384	phenazine biosynthesis protein PhzF
IC763_RS16210	COG3128	pkhd-type hydroxylase
IC763_RS16240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_RS16265	COG0583	DNA-binding transcription factor activity
IC763_RS16285	COG1053	succinate dehydrogenase
IC763_RS16300	COG1309	transcriptional regulator
IC763_RS16310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC763_RS16315	COG2814	Major facilitator Superfamily
IC763_RS16320	COG1960	acyl-CoA dehydrogenase activity
IC763_RS16325	COG0583	DNA-binding transcription factor activity
IC763_RS16365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC763_RS16385	COG2132	Multicopper oxidase
IC763_RS16395	COG0561	phosphatase activity
IC763_RS16400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC763_RS16410	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC763_RS16425	COG1214	PFAM Peptidase M22, glycoprotease
IC763_RS16475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC763_RS16485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC763_RS16490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC763_RS16495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC763_RS16555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC763_RS16565	COG1846	Transcriptional regulator
IC763_RS16570	COG1764	response to oxidative stress
IC763_RS16610	COG0037	tRNA processing
IC763_RS16620	COG0248	Ppx GppA phosphatase
IC763_RS16650	COG0072	phenylalanine-tRNA ligase activity
IC763_RS16680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC763_RS16690	COG1238	metal cluster binding
IC763_RS16695	COG0625	glutathione transferase activity
IC763_RS16710	COG0318	PFAM AMP-dependent synthetase and ligase
IC763_RS16715	COG3028	Belongs to the UPF0307 family
IC763_RS16740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC763_RS16745	COG0617	tRNA 3'-terminal CCA addition
IC763_RS16750	COG1555	photosystem II stabilization
IC763_RS16755	COG3956	TIGRFAM MazG family protein
IC763_RS16765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC763_RS16785	COG0784	Response regulator, receiver
IC763_RS16785	COG5002	protein histidine kinase activity
IC763_RS16785	COG2205	protein histidine kinase activity
IC763_RS16790	COG1024	Enoyl-CoA hydratase
IC763_RS16795	COG2084	Dehydrogenase
IC763_RS16800	COG3622	Belongs to the hyi family
IC763_RS16835	COG0697	spore germination
IC763_RS16845	COG2814	Major facilitator Superfamily
IC763_RS16855	COG3328	transposase activity
IC763_RS16865	COG0492	ferredoxin-NADP+ reductase activity
IC763_RS16870	COG0431	NADPH-dependent FMN reductase
IC763_RS16875	COG0798	PFAM Bile acid sodium symporter
IC763_RS16885	COG0640	Transcriptional regulator
IC763_RS16945	COG2205	protein histidine kinase activity
IC763_RS16980	COG3328	transposase activity
IC763_RS16990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC763_RS17000	COG0583	DNA-binding transcription factor activity
IC763_RS17010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC763_RS17090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC763_RS17100	COG1061	Type III restriction enzyme res subunit
IC763_RS17105	COG1002	Type II restriction enzyme, methylase subunits
IC763_RS17110	COG0084	hydrolase, TatD family'
IC763_RS17220	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC763_RS17225	COG0440	acetolactate synthase activity
IC763_RS17260	COG0577	efflux transmembrane transporter activity
IC763_RS17260	COG1136	(ABC) transporter
IC763_RS17265	COG1538	Outer membrane efflux protein
IC763_RS17280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC763_RS17295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC763_RS17370	COG0793	Belongs to the peptidase S41A family
IC763_RS17400	COG3265	gluconokinase activity
IC763_RS17410	COG0800	Aldolase
IC763_RS17425	COG0857	belongs to the CobB CobQ family
IC763_RS17425	COG0280	phosphate acetyltransferase
IC763_RS17430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC763_RS17430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC763_RS17450	COG0740	serine-type endopeptidase activity
IC763_RS17460	COG4774	siderophore transport
IC763_RS17470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC763_RS17480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC763_RS17480	COG2813	Specifically methylates the guanine in position
IC763_RS17575	COG0788	formyltetrahydrofolate deformylase activity
IC763_RS17600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC763_RS17600	COG4651	solute:proton antiporter activity
IC763_RS17620	COG0724	RNA recognition motif
IC763_RS17625	COG0210	DNA helicase
IC763_RS17650	COG1733	regulation of RNA biosynthetic process
IC763_RS17660	COG2900	Belongs to the SlyX family
IC763_RS17665	COG0488	(ABC) transporter
IC763_RS17675	COG1280	lysine exporter protein (LysE YggA)
IC763_RS17680	COG1560	Kdo2-lipid A biosynthetic process
IC763_RS17690	COG1301	dicarboxylic acid transport
IC763_RS17745	COG0473	3-isopropylmalate dehydrogenase activity
IC763_RS17770	COG0583	DNA-binding transcription factor activity
IC763_RS17815	COG0583	DNA-binding transcription factor activity
IC763_RS17825	COG0625	glutathione transferase activity
IC763_RS17830	COG2378	regulation of single-species biofilm formation
IC763_RS17845	COG1530	ribonuclease E activity
IC763_RS17850	COG0318	PFAM AMP-dependent synthetase and ligase
IC763_RS17865	COG0583	DNA-binding transcription factor activity
IC763_RS17870	COG4221	oxidoreductase activity
IC763_RS17885	COG0534	Mate efflux family protein
IC763_RS17900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC763_RS17930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC763_RS17930	COG0493	'glutamate synthase
IC763_RS17940	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC763_RS17960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC763_RS17970	COG0644	oxidoreductase
IC763_RS17970	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC763_RS17990	COG4535	Mg2 and Co2 transporter CorC
IC763_RS18000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC763_RS18025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC763_RS18030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC763_RS18030	COG0475	glutathione-regulated potassium exporter activity
IC763_RS18035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC763_RS18045	COG0484	heat shock protein binding
IC763_RS18050	COG0789	Transcriptional regulator
IC763_RS18055	COG0598	Magnesium transport protein CorA
IC763_RS18060	COG1185	polyribonucleotide nucleotidyltransferase activity
IC763_RS18070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC763_RS18075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_RS18080	COG1074	ATP-dependent DNA helicase activity
IC763_RS18085	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC763_RS18110	COG2226	methyltransferase
IC763_RS18125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_RS18140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC763_RS18155	COG2111	Na H antiporter
IC763_RS18155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC763_RS18160	COG1006	Multisubunit Na H antiporter MnhC subunit
IC763_RS18165	COG0651	ATP synthesis coupled electron transport
IC763_RS18170	COG1863	multisubunit Na H antiporter MnhE subunit
IC763_RS18175	COG2212	antiporter activity
IC763_RS18180	COG1320	monovalent cation:proton antiporter activity
IC763_RS18185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC763_RS18195	COG0195	Participates in both transcription termination and antitermination
IC763_RS18255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC763_RS18265	COG0497	DNA recombination
IC763_RS18275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC763_RS18290	COG1289	transmembrane transporter activity
IC763_RS18305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC763_RS18370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC763_RS18385	COG0326	Molecular chaperone. Has ATPase activity
IC763_RS18405	COG0596	Alpha beta hydrolase
IC763_RS18500	COG0546	phosphoglycolate phosphatase activity
IC763_RS18505	COG1716	ATPase activity
IC763_RS18550	COG0181	hydroxymethylbilane synthase activity
IC763_RS18580	COG1538	Outer membrane efflux protein
IC763_RS18590	COG0697	spore germination
IC763_RS18610	COG0494	nUDIX hydrolase
IC763_RS18620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC763_RS18625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC763_RS18630	COG0772	Belongs to the SEDS family
IC763_RS18655	COG4974	Belongs to the 'phage' integrase family
IC763_RS18670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC763_RS18680	COG2197	response regulator
IC763_RS18700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC763_RS18705	COG0795	lipopolysaccharide-transporting ATPase activity
IC763_RS18710	COG0795	lipopolysaccharide-transporting ATPase activity
IC763_RS18745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC763_RS18745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC763_RS18755	COG0004	ammonium transporteR
IC763_RS18760	COG0347	Belongs to the P(II) protein family
IC763_RS18770	COG0606	chelatase, subunit chli
IC763_RS18775	COG0431	NADPH-dependent FMN reductase
IC763_RS18780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_RS18785	COG0235	Class ii aldolase
IC763_RS18790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC763_RS18805	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC763_RS18830	COG0477	Major facilitator Superfamily
IC763_RS18835	COG2860	membrane
IC763_RS18845	COG1253	flavin adenine dinucleotide binding
IC763_RS18855	COG2814	Major facilitator Superfamily
IC763_RS18865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC763_RS18900	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC763_RS18915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC763_RS18950	COG1309	transcriptional regulator
IC763_RS18985	COG0758	DNA mediated transformation
IC763_RS18995	COG0697	spore germination
IC763_RS19000	COG1309	transcriptional regulator
IC763_RS19015	COG0386	Belongs to the glutathione peroxidase family
IC763_RS19025	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC763_RS19030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC763_RS19080	COG1121	(ABC) transporter
IC763_RS19085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC763_RS19090	COG1280	lysine exporter protein (LysE YggA)
IC763_RS19095	COG2837	iron assimilation
IC763_RS19105	COG0281	malic enzyme
IC763_RS19140	COG0735	belongs to the Fur family
IC763_RS19150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC763_RS19155	COG0519	Catalyzes the synthesis of GMP from XMP
IC763_RS19155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC763_RS19160	COG4399	Belongs to the UPF0754 family
IC763_RS19165	COG2259	Doxx family
IC763_RS19170	COG0586	Pfam SNARE associated Golgi protein
IC763_RS19185	COG1192	Involved in chromosome partitioning
IC763_RS19195	COG0271	Belongs to the BolA IbaG family
IC763_RS19230	COG3756	Protein conserved in bacteria
IC763_RS19240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC763_RS19305	COG3550	peptidyl-serine autophosphorylation
IC763_RS19310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC763_RS19315	COG2963	transposase activity
IC763_RS19325	COG4372	Transposase
IC763_RS19405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC763_RS19405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC763_RS19405	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC763_RS19405	COG3321	synthase
IC763_RS19410	COG1960	acyl-CoA dehydrogenase activity
IC763_RS19425	COG2197	response regulator
IC763_RS19435	COG3916	Acyl-homoserine-lactone synthase
IC763_RS19440	COG0477	Major facilitator Superfamily
IC763_RS19445	COG1024	Enoyl-CoA hydratase
IC763_RS19450	COG1024	Enoyl-CoA hydratase
IC763_RS19455	COG1960	acyl-CoA dehydrogenase activity
IC763_RS19460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC763_RS19480	COG1113	amino acid transport
IC763_RS19485	COG1113	amino acid transport
IC763_RS19490	COG0251	oxidation-reduction process
IC763_RS19530	COG0564	pseudouridine synthase activity
IC763_RS19550	COG3328	transposase activity
IC763_RS19605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC763_RS19620	COG1802	Transcriptional regulator
IC763_RS19630	COG1448	Aminotransferase
IC763_RS19635	COG0277	FAD linked oxidase domain protein
IC763_RS19645	COG2186	Transcriptional regulator
IC763_RS19655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC763_RS19665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC763_RS19680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC763_RS19690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IC763_RS19750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC763_RS19770	COG1596	polysaccharide export
IC763_RS19795	COG0728	peptidoglycan biosynthetic process
IC763_RS19800	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC763_RS19855	COG0546	phosphoglycolate phosphatase activity
IC763_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_RS19875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC763_RS19875	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC763_RS19880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_RS19885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_RS19890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_RS19895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_RS19900	COG1116	anion transmembrane transporter activity
IC763_RS19905	COG1309	transcriptional regulator
IC763_RS19910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC763_RS19920	COG0196	riboflavin kinase activity
IC763_RS19925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC763_RS19935	COG1047	Peptidyl-prolyl cis-trans
IC763_RS19975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC763_RS19980	COG0657	acetylesterase activity
IC763_RS20035	COG2951	lytic endotransglycosylase activity
IC763_RS20040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC763_RS20055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC763_RS20065	COG0671	phosphoesterase, PA-phosphatase related
IC763_RS20070	COG0861	Integral membrane protein TerC family
IC763_RS20080	COG0402	S-adenosylhomocysteine deaminase activity
IC763_RS20095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC763_RS20305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC763_RS20385	COG2826	transposase and inactivated derivatives, IS30 family
IC763_RS20395	COG2826	transposase and inactivated derivatives, IS30 family
IC763_RS20560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC763_RS20615	COG1525	nuclease
IC763_RS20625	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IC763_RS20630	COG3421	Type III restriction
IC763_RS20695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC763_RS20780	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC763_RS20840	COG1538	Outer membrane efflux protein
IC763_RS20845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_RS20855	COG0745	RESPONSE REGULATOR receiver
IC763_RS20880	COG0488	(ABC) transporter
IC763_RS20900	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_RS20905	COG3657	addiction module killer protein
IC763_RS20955	COG0659	secondary active sulfate transmembrane transporter activity
IC763_RS20960	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_RS20965	COG3657	addiction module killer protein
IC763_RS21020	COG2814	Major facilitator Superfamily
IC763_RS21035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC763_RS21040	COG2076	Multidrug Resistance protein
IC763_RS21075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC763_RS21095	COG4372	Transposase
IC763_RS21390	COG1192	Involved in chromosome partitioning
IC763_RS21395	COG1475	DNA binding
IC763_RS21620	COG0789	Transcriptional regulator
IC763_RS21795	COG3328	transposase activity
IC763_RS21865	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC763_RS21895	COG4221	oxidoreductase activity
IC763_RS21900	COG0583	DNA-binding transcription factor activity
IC763_RS21910	COG0604	alcohol dehydrogenase
IC763_RS21910	COG3321	synthase
IC763_RS21915	COG0583	DNA-binding transcription factor activity
IC763_RS21925	COG3657	addiction module killer protein
IC763_RS21930	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_RS21950	COG3657	addiction module killer protein
IC763_RS21955	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_RS21975	COG1063	alcohol dehydrogenase
IC763_RS22005	COG1979	alcohol dehydrogenase
IC763_RS22015	COG1902	pentaerythritol trinitrate reductase activity
IC763_RS22025	COG1309	transcriptional regulator
IC763_RS22030	COG2130	NADP-dependent
IC763_RS22045	COG0582	viral genome integration into host DNA
IC763_RS22115	COG0589	response to stress